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Hironori Ohinata
Faculty of Health Sciences　Health Sciences　Fundamental Nursing
Assistant Professor
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Last Updated :2024/05/09

Researcher Profile and Settings

Affiliation

  • Faculty of Health Sciences　Health Sciences　Fundamental Nursing

Job Title

  • Assistant Professor

ORCID ID

J-Global ID

Research Areas

  • Life sciences / Clinical nursing

Education

  • 2020/04 - 2023/03  Tohoku University  Graduate School of Medicine  Department of Palliative Nursing
  • 2018/04 - 2020/03  Keio University  Graduate School of Health Management

Research Activities

Published Papers

  • Hironori Ohinata, Hideyuki Hirayama, Maho Aoyama, Eriko Satomi, Yoshiyuki Kizawa, Mayuko Miyazaki, Keita Tagami, Ryuichi Sekine, Kozue Suzuki, Nobuyuki Yotani, Koji Sugano, Hirofumi Abo, Akihiro Sakashita, Kazuki Sato, Sari Nakagawa, Yoko Nakazawa, Jun Hamano, Mitsunori Miyashita
    Progress in Palliative Care 2024/02/07
  • Shintaro Togashi, Hironori Ohinata, Taiji Noguchi, Hidetaka Wakabayashi, Mariko Nakamichi, Akio Shimizu, Shinta Nishioka, Ryo Momosaki
    Annals of geriatric medicine and research 2024/01/17 
    BACKGROUND: Although the relationship between medication status, symptomatology, and outcomes has been evaluated, data on the prevalence of polypharmacy and potentially inappropriate medications (PIMs) and the association of polypharmacy and PIMs with swallowing function during follow-up are limited among hospitalized patients aged ≥65 years with dysphagia. METHODS: In this 19-center cohort study, we registered 467 inpatients aged ≥65 years and evaluated those with the Food Intake LEVEL Scale (FILS) scores ≤8 between November 2019 and March 2021. Polypharmacy was defined as prescribing ≥5 medications and PIMs were identified based on the 2023 Updated Beers criteria®. We applied a generalized linear regression model to examine the association of polypharmacy and PIMs with FILS score at discharge. RESULTS: We analyzed 399 participants (median age, 83.0 years; males, 49.8%). The median follow-up was 51.0 days interquartile range, 22.0-84.0 days]. Polypharmacy and PIMs were present in 67.7% of and 56.1% of patients, respectively. After adjusting for covariates, neither polypharmacy (β = 0.05 [95% confidence interval (CI), -0.04-0.13], p = 0.30) nor non-steroidal anti-inflammatory medications (β = 0.09 [95%CI, -0.02-0.19], p = 0.10) were significantly associated with FILS score at discharge. CONCLUSIONS: The results of this study indicated a high proportion of polypharmacy and PIMs among inpatients aged ≥65 years with dysphagia. Although these prescribed conditions were not significantly associated with swallowing function at discharge, our findings suggest the importance of regularly reviewing medications to ensure the appropriateness of prescriptions when managing older inpatients.
  • 大日方裕紀, 大日方裕紀, 青山真帆, 宮下光令
    日本がん看護学会誌(Web) 37 2189-7565 2023
  • Hironori Ohinata, Maho Aoyama, Yusuke Hiratsuka, Masanori Mori, Ayako Kikuchi, Hiroaki Tsukuura, Yosuke Matsuda, Kozue Suzuki, Hiroyuki Kohara, Isseki Maeda, Tatsuya Morita, Mitsunori Miyashita
    BMJ supportive & palliative care 2022/10/27 
    OBJECTIVES: To clarify the relationship between Phase of Illness at the time of admission to palliative care units and symptoms of patients with advanced cancer. METHODS: This study was a secondary analysis of the East Asian collaborative cross-cultural Study to Elucidate the Dying process. Palliative physicians recorded data, including Phase of Illness, physical function and the Integrated Palliative care Outcome Scale. We used multinomial logistic regression to analyse ORs for factors associated with Phase of Illness. Twenty-three palliative care units in Japan participated from January 2017 to September 2018. RESULTS: In total, 1894 patients were analysed-50.9% were male, mean age was 72.4 (SD±12.3) years, and Phase of Illness at the time of admission to the palliative care unit comprised 177 (8.9%) stable, 579 (29.2%) unstable, 921 (46.4%) deteriorating and 217 (10.9%) terminal phases. Symptoms were most distressing in the terminal phase for all items, followed by deteriorating, unstable and stable (p<0.001). The stable phase had lower association with shortness of breath (OR 0.73, 95% CI 0.57 to 0.94) and felt at peace (OR 0.73, 95% CI 0.56 to 0.90) than the unstable phase. In the deteriorating phase, weakness or lack of energy (OR 1.20, 95% CI 1.02 to 1.40) were higher, while drowsiness (OR 0.82, 95% CI 0.71 to 0.97) and felt at peace (OR 0.81, 95% CI 0.71 to 0.94) were significantly lower. CONCLUSION: Our study is reflective of the situation in palliative care units in Japan. Future studies should consider the differences in patients' medical conditions and routinely investigate patients' Phase of Illness and symptoms. TRIAL REGISTRARION NUMBER: UMIN000025457.
  • Shintaro Togashi, Hidetaka Wakabayashi, Hironori Ohinata, Shinta Nishioka, Yoji Kokura, Ryo Momosaki
    Nutrients 14 (21) 2022/10/26 
    The accuracy of body mass index (BMI) for sarcopenic dysphagia diagnosis, which remains unknown, was evaluated in this study among patients with dysphagia. We conducted a 19-site cross-sectional study. We registered 467 dysphagic patients aged ≥ 20 years. Sarcopenic dysphagia was assessed using a reliable and validated diagnostic algorithm. BMI was assessed using the area under the curve (AUC) in the receiver operating characteristic analysis to determine diagnostic accuracy for sarcopenic dysphagia. The study included 460 patients (median age, 83.0 years (76.0-88.0); men, 49.8%). The median BMI was 19.9 (17.3-22.6) kg/m2. Two hundred eighty-four (61.7%) patients had sarcopenic dysphagia. The AUC for sarcopenic dysphagia was 0.60-0.62 in the overall patients, male, female, and patients aged ≥ 65 years The BMI cut-off value for sarcopenic dysphagia diagnosis was 20.1 kg/m2 in the overall patients (sensitivity, 58.1%; specificity, 60.2%) and patients aged ≥ 65 years (sensitivity, 59.8%; specificity, 61.8%). Conclusion: Although the AUC, sensitivity and specificity of BMI for sarcopenic dysphagia diagnosis was approximately 0.6, BMI < 20.0 kg/m2 might be a predictor for sarcopenic dysphagia. In clinical settings, if patients with dysphagia have a BMI < 20.0 kg/m2, then sarcopenic dysphagia should be suspected as early as possible after admission.
  • Hironori Ohinata, Maho Aoyama, Mitsunori Miyashita
    Annals of palliative medicine 2022/09/30 
    BACKGROUND: People receiving palliative care have complex, wide-ranging, and changing needs, not just physical distress, but also psychosocial, practical, and spiritual. Influences on complexity in palliative care are different among healthcare providers and may depend on diverse aspects of the patient's condition, time, and environment. Therefore, this study aimed to integrate and describe the perspective of complexity in palliative care. METHODS: We used an integrative review, which is a method of compiling, summarizing, and analyzing existing insights from previous studies. We conducted an electronic literature search in MEDLINE (Ovid), PsycINFO (EBSCOhost), Web of Science Core Collection, and CINAHL (EBSCOhost), examining literature from May 1972 to September 2020 and updated in December 2020. Subsequently, synthesis without meta-analysis of the findings was completed. RESULTS: We identified 32 peer-reviewed articles published in English. The included literature mainly originated in Europe and the United States. The research methods included quantitative studies (n=13), qualitative studies (n=12), case studies (n=3), and reviews (n=4). We identified 29 that influenced complexity in palliative care, 25 perceptions of the patient, including background and physical, psychological, social, and spiritual; two perceptions in the healthcare setting; and two perceptions in the socio-cultural setting. Above all, the perceptions of complexity in palliative care included younger age, prognosis, and spirituality. In addition, we added the identified perceptions of complexity with references to the complexity model in palliative care. DISCUSSION: Although this review was limited in its search strategy and some data sources may have been overlooked, it still provided perceptions that influenced complexity in palliative care. These complex influencing perceptions are necessary for patients to receive appropriate palliative care at the right time and for health care providers to conduct a multi-disciplinary team approach. Furthermore, longitudinal prospective data are needed to examine the changes and relationships among complexity over time.
  • Ohinata Hironori, Yagasaki Kaori, Hamamoto Yasuo, Hirata Kenro, Sukawa Yasutaka, Komatsu Hiroko
    Journal of Japan Academy of Nursing Science 公益社団法人 日本看護科学学会 42 254 - 262 0287-5330 2022 
    Aim: The study aimed to investigate the relationship between frailty and quality of life (QOL) in older patients with gastrointestinal cancer at the time when an anticancer drug regimen is changed. Methods: We conducted a cross-sectional observational study of gastrointestinal cancer patients aged 65 years or older at the time of anticancer drug change. Frailty and QOL were measured using G8 and EQ-5D-5L. Results: Fifty-one patients agreed to participate in this study. Data collection and analysis were conducted. Forty (78.4%) older patients with gastrointestinal cancer were considered frail. Flail group had a lower BMI (p < .001), thinner calf (p = .023), and lower quality of life (p = .04) compared to the non-frail group. Conclusion: This study showed the characteristics of frail patients with gastrointestinal cancer when changing anticancer drug regimen and the population that is vulnerable to falling into the frail cycle. The assessment of frailty in older cancer patients receiving anticancer drugs was an essential factor for QOL-conscious treatment decision.

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