Researcher basic information

• Ph.D., Hokkaido University, Jun. 2022

• https://researchmap.jp/kazuyoshi_sasaoka?lang=en

• https://orcid.org/0000-0002-2990-7808
• https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201901001153172864
• https://www.vetmed.hokudai.ac.jp/VMTH/department/neurology/

• https://orcid.org/0000-0002-2990-7808

• ABA-2872-2021

• 201901001153172864

• Neurosonology
• Neurology
• Dogs, Cats
• Diagnostic Imaging
• Clinical veterinary science
• Infection Control

• Life Science, Veterinary medical science, Clinical veterinary science
• Life Science, Veterinary medical science, Clinical veterinary neurology
• Life Science, Veterinary medical science, Infection Control

• Doctoral (PhD) degree program, Graduate School of Veterinary Medicine

Research activity information

• Aug. 2025, The Hokkaido Veterinary Medical Association, President's Award
  A Cat with White Matter Atrophy Evaluated Using Diffusion Tensor Imaging (DTI)
  Kana Nakamura;Kazuyoshi Sasaoka;Genya Shimbo;Yoshihisa Yamane;Kensuke Nakamura;Mitsuyoshi Takiguchi, Japan society, Japan
• Aug. 2025, The Hokkaido Veterinary Medical Association, President's Award
  A Case of Gliomatosis Cerebri in a French Bulldog Presenting with Behavioral Abnormalities
  Fumi Kato;Kazuyoshi Sasaoka;Genya Shimbo;Ai Koshikawa;Takashi Kimura;Mitsuyoshi Takiguchi, Japan society, Japan
• Jun. 2025, Japanese Society of Veterinary Neurology, TOKURIKI Award
  Assessment of Cerebral Blood Flow by Transcranial Ultrasonography in Comatose Cases Suspected of Brain Death
  Kazuyoshi Sasaoka, 32431100;32431104
• May 2025, The Japanese Society of Veterinary Science, Veterinary Science Young Investigator Award
  Studies on the clinical usefulness of the evaluation of cerebral blood flow by Transcranial Doppler ultrasonography in dogs
  Kazuyoshi Sasaoka, 32431100;13227274;13227273
• Sep. 2024, The Hokkaido Veterinary Medical Association, Chairperson’s Award
  Impaired Consciousness Is Associated with Poor Prognosis in Meningoencephalomyelitis of Unknown Origin (MUO): A Retrospective Study of 82 Cases (2014–2022)
  Kazuyoshi Sasaoka;Tomoki Fuke;Takafumi Sunaga;Hiroshi Ohta;Mitsuyoshi Takiguchi, Japan society, Japan
• Sep. 2023, The Japanese Society of Veterinary Science, Excellent Presentation Award (Clinical Section)
  A Standard Infection Control Program Contributes to Improved Hand Hygiene Compliance and Suppression of Multidrug-Resistant Bacteria in Veterinary Hospitals
  Kazuyoshi Sasaoka
• Aug. 2023, The Hokkaido Veterinary Medical Association, President's Award
  A Retrospective Study of 23 Dogs with Paroxysmal Dyskinesia
  Yuki Kawakami;Kazuyoshi Sasaoka;Hiroshi Ohta;Yoshihisa Yamane;Genya Shimbo;Nozomu Yokoyama;Noboru Sasaki;Keitaro Morishita;Kensuke Nakamura;Mitsuyoshi Takiguchi
• Jun. 2023, The Japanese Society of Veterinary Science, 2022 JVMS Excellent Paper Award
  Local cerebral blood flow assessment using transcranial Doppler ultrasonography in a dog with brain infarction in the right middle cerebral artery territory
  Kazuyoshi Sasaoka, 32431100
• Sep. 2022, The Hokkaido Veterinary Medical Association, President's Award
  Alert on Moist Environments in an Animal Hospital: Results of Environmental Surveillance at the Hokkaido University Veterinary Teaching Hospital
  Kazuyoshi Sasaoka;Yurika Nitta;Toyotaka Sato;Motohiro Horiuchi;Mitsuyoshi Takiguchi
• Sep. 2021, The Japanese Society of Veterinary Science, 2020 JVMS Excellent Paper Award
  An area ratio of thyroid gland to common carotid artery for evaluating the thyroid gland size.
  Sasaki N.;Nagata N.;Morishita K.;Osuga T.;Sasaoka K.;Yokoyama N.;Ohta H.;Takiguchi M.
• Sep. 2021, The Japanese Society of Veterinary Science, Good Reviewer Award in 2020
  Kazuyoshi Sasaoka
• Mar. 2018, Japanese Society of Veterinary Clinical Nutrition, Best Research Award
  Trace Elemental Profiles of Serum and Cerebrospinal Fluid in Dogs with Idiopathic Epilepsy
  笹岡一慶, Publisher, Japan
• Nov. 2017, Asian Meeting of Animal Medicine Specialties 2017, Best Poster Award
  Relationship between transcranial Doppler ultrasound vascular resistance parameters and intracranial hypertension in clinical dogs
  笹岡一慶, International society, Korea, Republic of
• Feb. 2013, Japan College of Veterinary Internal Medicine, Clinical Study Award
  The usefulness of transcranial Doppler ultrasound for the diagnosis of canine intracranial disease
  笹岡一慶, Japan society, Japan
• Jul. 2008, Hokkaido University, Nitobe award
  笹岡一慶, Others, Japan

• Impact of Thawing Conditions on Microstructure, Texture, and Sensory Quality of Frozen‑Thawed Rainbow Trout Sashimi: A Machine Learning‑Assisted Microstructural Analysis
  Yukiho Sasaoka; Kazuyoshi Sasaoka; Shotaro Sakimura; Yumi Hamakawa; Akiko Miyazaki; Shingo Aso
  Food and Humanity, Apr. 2026, [Peer-reviewed], [Lead author], [International Magazine]
  Scientific journal
• Potential human health risk of carbapenem-non-susceptible Pseudomonas aeruginosa from companion animals
  Jirachaya Toyting-Hiraishi; Toyotaka Sato; Mana Tohyama; Taro Fujino; Kaho Okada; Kazuyoshi Sasaoka; Nozomu Yokoyama; Kana Torii; Akio Suzuki; Yuzo Tsuyuki; Kensuke Nakamura; Mitsuyoshi Takiguchi; Motohiro Horiuchi
  Journal of Antimicrobial Chemotherapy, 80, 11, 3043, 3056, Oxford University Press (OUP), 19 Sep. 2025, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Abstract
  
  Background and objectives
  
  The close bond between companion animals and humans may accelerate the spread of antimicrobial-resistant bacteria. Pseudomonas aeruginosa, an opportunistic pathogen in both, poses a public health threat due to antimicrobial resistance (AMR) and diverse virulence factors. However, One Health-based comparison remains limited. This study investigated the current AMR status and molecular characteristics of P. aeruginosa in companion animals in Japan to assess potential human health risks.
  
  Methods
  
  We examined 197 P. aeruginosa clinical isolates from companion animals [dogs (n = 99) and cats (n = 98)] across Japan in 2024. Antimicrobial susceptibility to human clinical antibiotics was evaluated. In carbapenem-non-susceptible isolates, multilocus sequence typing and detection of resistance genes and virulence factors were performed.
  
  Results
  
  Ciprofloxacin (20.3%) and piperacillin (10.7%) showed the highest resistance rates, with 5.6% of isolates being multidrug-resistant. Carbapenem resistance rates were 6.1% for imipenem and 1.0% for meropenem. Thirty-five isolates (17.8%) exhibited carbapenem non-susceptibility but remained susceptible to cefepime, ciprofloxacin, or amikacin. Of 27 identified sequence types, 20 (77.1% of carbapenem-non-susceptible isolates) were known in humans, including two high-risk clones (ST233 and ST298; 8.6%) reported for the first time in Japanese companion animals. These isolates carried mutations in efflux pump-related genes and multiple virulence factors. One showed close genetic relatedness to a human isolate, suggesting possible interspecies transmission.
  
  Conclusions
  
  Our findings highlight the potential cross-species transmission risk of antimicrobial-resistant P. aeruginosa. Identification of shared high-risk clones with multiple virulence factors emphasizes the need for continuous vigilance and actions within the One Health framework.
• Outcomes and Prognostic Factors in Dogs With Presumed Intracranial Gliomas Treated With Definitive‐Intent Intensity Modulated Radiation Therapy: 55 Cases (2014–2023)
  Yohichi Fukuyama; Kenji Hosoya; Sangho Kim; Koangyong Sung; Tatsuya Deguchi; Genya Shimbo; Kazuyoshi Sasaoka; Ryouhei Kinoshita; Mitsuyoshi Takiguchi
  Veterinary and Comparative Oncology, 25 Aug. 2025, [Peer-reviewed]
  Scientific journal
• Evaluation of the course of improvement with molnupiravir treatment for feline infectious peritonitis
  Shino Yoshida; Mei Sugawara-Suda; Kazuyoshi Sasaoka; Noboru Sasaki; Nozomu Yokoyama; Kensuke Nakamura; Keitaro Morishita; Sangho Kim; Takafumi Sunaga; Mitsuyoshi Takiguchi
  Canadian Veterinary Journal, 66, 5, 546, 554, May 2025, [Peer-reviewed], [International Magazine]
  English, Scientific journal
• Case report: Echinococcus multilocularis infection in a dog showing gastrointestinal signs in Hokkaido, Japan
  Izumi Kida; Naoki Hayashi; Nozomu Yokoyama; Noriyuki Nagata; Kazuyoshi Sasaoka; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hirokazu Kouguchi; Kinpei Yagi; Ryo Nakao; Mitsuyoshi Takiguchi; Nariaki Nonaka
  Frontiers in Veterinary Science, 11, Frontiers Media SA, 13 Jun. 2024, [Peer-reviewed]
  Scientific journal, Echinococcus multilocularis is a cestode that causes human alveolar echinococcosis, a lethal zoonotic disease distributed in the northern hemisphere. The life cycle of this parasite is maintained in nature by voles as intermediate hosts and foxes as definitive hosts in Hokkaido, Japan. Although dogs are also susceptible to the parasite, the infection has been considered typically asymptomatic. We report the detection of E. multilocularis eggs in the diarrheal feces of a dog with chronic gastrointestinal signs, which disappeared after anthelmintic treatment. The mitochondrial genome sequence constructed by sequencing of the overlapping PCRs using DNA from the eggs was identical to the most predominant haplotype previously reported in red foxes in Hokkaido. This case highlights that Echinococcus infection should be considered as a differential diagnosis for diarrheal dogs in the disease endemic areas. Further efforts are needed to accumulate parasite genotypes in domestic dogs as well as humans to assess the risk of human infection from dogs.
• Antimicrobial resistance and self-reported hand hygiene awareness before and after an infection prevention and control programme: a 7-year analysis in a small animal veterinary teaching hospital
  K. Sasaoka; T. Sato; K. Morishita; K. Hosoya; N. Yokoyama; T. Sato; M. Horiuchi; M. Takiguchi
  The Veterinary Journal, 106154, 106154, Elsevier BV, May 2024, [Peer-reviewed], [Lead author], [International Magazine]
  English, Scientific journal
• Successful treatment of sclerosing encapsulating peritonitis in a cat using bioresorbable hyaluronate-carboxymethylcellulose membrane after surgical adhesiolysis and long-term prednisolone
  Nozomu Yokoyama; Ryohei Kinoshita; Hiroshi Ohta; Kazuki Okada; Genya Shimbo; Kazuyoshi Sasaoka; Noriyuki Nagata; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Yumiko Kagawa; Mitsuyoshi Takiguchi
  Journal of Feline Medicine and Surgery Open Reports, 9, 2, SAGE Publications, Jul. 2023, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Case summary
  
  An 8-year-old neutered male domestic shorthair indoor cat was presented with an 8-week history of intermittent vomiting, anorexia and weight loss that had been unresponsive to supportive treatment. Abdominal ultrasound revealed plication of the small intestine and fluid accumulation proximal to the lesion, and a linear foreign body was suspected. An exploratory celiotomy showed cocoon-like encapsulation of the entire intestine. Surgical adhesiolysis and full-thickness biopsy were performed, and histopathologic examination revealed mild thickening of the visceral peritoneum with fibrin deposition, as well as mild neutrophil and lymphocyte infiltration. These findings were compatible with sclerosing encapsulating peritonitis (SEP). The cat recovered well postoperatively and was discharged the next day. Prednisolone was administered for 7 weeks to prevent recurrence of SEP. Five months after surgery, the cat was re-presented with anorexia and chronic vomiting. Based on the clinical examination findings, recurrent SEP was suspected. At the second surgery, surgical adhesiolysis was repeated and a bioresorbable hyaluronate-carboxymethylcellulose membrane was used to cover the serosal surface and thus prevent adhesion formation. Histopathologic findings of the peritoneal biopsy specimen confirmed SEP. Long-term prednisolone treatment (1 mg/kg for the first dose and 0.5 mg/kg every 48 h for maintenance) was administered postoperatively. The cat survived for more than 1239 days without recurrence.
  
  Relevance and novel information
  
  To our knowledge, this is the first report of SEP in a cat with long-term survival. The use of a bioresorbable hyaluronate-carboxymethylcellulose membrane and long-term prednisolone treatment may have prevented short-term and long-term recurrence, respectively, in this case.
• Local cerebral blood flow assessment using transcranial Doppler ultrasonography in a dog with brain infarction in the right middle cerebral artery territory
  Kazuyoshi SASAOKA; Hiroshi OHTA; Tomohito ISHIZUKA; Tatsuyuki OSUGA; Keitaro MORISHITA; Noboru SASAKI; Mitsuyoshi TAKIGUCHI
  Journal of Veterinary Medical Science, 84, 10, 1385, 1390, Japanese Society of Veterinary Science, Oct. 2022, [Peer-reviewed], [Lead author], [Domestic magazines]
  English, Scientific journal, A 12-year-old neutered male Chihuahua was diagnosed with acute brain infarction in the right middle cerebral artery (MCA) territory. Transcranial Doppler ultrasonography (TCD) was performed to assess the local cerebral blood flow at the time of diagnosis and after 4 and 31 hr. Initially, the right MCA retained blood flow but with a lower cerebral blood flow velocity (CBFV; 14.9 cm/sec) than the left MCA (27.9 cm/sec). The TCD vascular resistance variables were higher in the right than in the left MCA. An increase in the CBFV and a decrease in TCD vascular resistance variables were observed, consistent with improvements in neurological symptoms. TCD can be a non-invasive, and easy-to-use modality for bedside monitoring of cerebral edema and infarction., 32431100
• Serum steroid profiling of hepatocellular carcinoma associated with hyperadrenocorticism in dogs: A preliminary study
  Thandar Oo; Noboru Sasaki; Yoshinori Ikenaka; Takahiro Ichise; Noriyuki Nagata; Nozomu Yokoyama; Kazuyoshi Sasaoka; Keitaro Morishita; Kensuke Nakamura; Mitsuyoshi Takiguchi
  Frontiers in Veterinary Science, 9, 1014792, 1014792, Frontiers Media SA, Sep. 2022, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Background
  
  Hepatocellular carcinoma (HCC) is one of the most common primary liver tumors in humans and dogs. Excessive adrenocortical hormone exposure may cause steroid hepatopathy, which may develop into HCC. In our previous study, hyperadrenocorticism (HAC) was a highly concurrent disease in dogs with HCC. Therefore, this study hypothesized that adrenal steroid alterations might be involved in hepatocarcinogenesis and aimed to specify the relationship between HAC and HCC in dogs.
  
  Materials and methods
  
  This study included 46 dogs brought to the Hokkaido University Veterinary Teaching Hospital between March 2019 and December 2020. Owners gave their signed consent for blood collection on their first visit. A total of 19 steroids (14 steroids and 5 metabolites) in the baseline serum of 15 dogs with HCC, 15 dogs with HAC, and 10 dogs with both diseases were quantitatively measured using the developed liquid chromatography coupled with tandem mass spectrometry (LC/MS/MS) method.
  
  Results
  
  In each group, 11 steroids were detected higher than 50%. The detection rate of steroid hormones did not significantly differ between the groups (p > 0.05). Principle component analysis (PCA) showed that the steroid profiles of the three groups were comparable. Median steroid hormone concentrations were not significantly different between the study diseases (p > 0.05).
  
  Conclusion
  
  The developed LC/MS/MS was useful for measuring steroid hormones. Although it was clear that HAC was concurrent in dogs with HCC, none of the serum steroids was suggested to be involved in HCC.
• Malignant oligoastrocytoma in the spinal cord of a cat
  Dai HASEGAWA; Keisuke AOSHIMA; Kazuyoshi SASAOKA; Atsushi KOBAYASHI; Mitsuyoshi TAKIGUCHI; Takashi KIMURA
  Journal of Veterinary Medical Science, 84, 9, 1277, 1282, Japanese Society of Veterinary Science, Sep. 2022, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, A 12-year and 3-month spayed female mixed cat was presented with severe lumbar pain. Magnetic resonance imaging and postmortem examination revealed a swollen lesion in the spinal cord at L3 level. Histologic examination identified extensive neoplastic cell proliferation with massive necrosis in the tumor tissue. Two types of neoplastic cells were recognized. One type of neoplastic cells were large cells characterized by round to polygonal shape and abundant eosinophilic cytoplasm (referred to as "large cells"). The other neoplastic cells were small, densely proliferated, and had round to irregular shape and scant eosinophilic cytoplasm (referred to as "small cells"). Both types of cells were positive for oligodendrocyte transcription factor 2 and SRY-box transcription factor 10. Glial fibrillary acidic protein was positive in large cells but negative in most small cells. Digital analysis for Ki-67-stained tumor tissues found that total 21.1% ± 6.5% of tumor cells were positive for Ki-67. Based on these findings, we diagnosed malignant oligoastrocytoma in the spinal cord.
• Urinary corticoid to creatinine ratios using IMMULITE 2000 XPi for diagnosis of canine hypercortisolism.
  Noriyuki Nagata; Hiryu Sawamura; Keitaro Morishita; Kenji Hosoya; Nozomu Yokoyama; Kazuyoshi Sasaoka; Noboru Sasaki; Kensuke Nakamura; Yoshinori Ikenaka; Mitsuyoshi Takiguchi
  The Journal of veterinary medical science, 84, 7, 954, 959, May 2022, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, The urinary corticoid to creatinine ratio (UCCR) is one of the most commonly used screening tests for canine hypercortisolism (HC). In this study, a reference interval was established for UCCR using IMMULITE 2000 XPi, the latest chemiluminescence enzyme immunoassay. The diagnostic performance of this method for UCCR in canine HC was also evaluated. The median UCCR was 1.06 × 10-5 (range: 0.28-2.49) for 58 healthy dogs, and an upper reference limit of 1.98 × 10-5 (90% confidence interval: 1.76-2.15) was determined. The median UCCR in the 12 dogs with HC (7.38 × 10-5, range 1.86-29.98) was significantly higher than that in the 16 dogs with mimic-HC (1.59 × 10-5, range 0.47-3.42, P<0.001). The area under the curve for UCCR to differentiate HC dogs from mimic-HC dogs was 0.971, with a sensitivity of 91.7% and specificity of 100% when the cut-off value was set at 3.77 × 10-5. The UCCR of 16 paired urine samples collected at home and in hospital showed that the UCCR of samples collected in the hospital was significantly higher than that of samples collected at home (mean difference 3.30 × 10-5, 95% confidence interval: 0.70-5.90, P=0.001). In summary, we established the upper reference limit for UCCR using IMMULITE 2000 XPi in dogs and confirmed that UCCR is a useful diagnostic test for HC in dogs if urine samples are collected at home.
• Transcranial Doppler ultrasonography detects the elevation of cerebral blood flow during ictal-phase of pentetrazol-induced seizures in dogs
  Kazuyoshi Sasaoka; Hiroshi Ohta; Tomohito Ishizuka; Kazuki Kojima; Noboru Sasaki; Mitsuyoshi Takiguchi
  American Journal of Veterinary Research, 83, 4, 331, 338, American Veterinary Medical Association (AVMA), Apr. 2022, [Peer-reviewed], [Lead author], [International Magazine]
  English, Scientific journal, Objective: To investigate the association between changes in cerebral blood flow and electrographic epileptic seizure in dogs using transcranial Doppler ultrasonography (TCD).
  
  Animals: 6 healthy Beagle dogs.
  
  Procedures: Each dog was administered pentetrazol (1.5 mg/kg/min) or saline (0.9% NaCl) solution under general anesthesia with continuous infusion of propofol. Both pentetrazol and saline solution were administered to all 6 dogs, with at least 28 days interval between the experiments. Blood flow waveforms in the middle cerebral artery and the basilar artery were obtained using TCD at baseline, after pentetrazol administration, and after diazepam administration. TCD velocities, including peak systolic velocity, end-diastolic velocity, and mean velocity and resistance variables, were determined from the Doppler waveforms.
  
  Results: During ictal-phase of pentetrazol-induced seizures, the TCD velocities significantly increased in the basilar and middle cerebral arteries while TCD vascular resistance variables did not change in either artery. The TCD velocities significantly decreased after diazepam administration. Systemic parameters, such as the heart rate, mean arterial pressure, systemic vascular resistance, cardiac index, end-tidal carbon dioxide, oxygen saturation, and body temperature, did not change significantly during seizures.
  
  Clinical relevance: This study showed that cerebral blood flow, as obtained from TCD velocities, increased by 130% during ictal-phase of pentetrazol-induced seizures in dogs. The elevated velocities returned to baseline after seizure suppression. Thus, TCD may be used to detect electrographic seizures during the treatment of status epilepticus in dogs, and further clinical studies clarifying the association between changes in cerebral blood flow and non-convulsive seizure cases are needed., 32431104
• Systemic mucoid degeneration of the arterial tunica intima in a young dog.
  Yoshiki Ichikawa; Mizuki Heishima; Kristin Vyhnal; Keisuke Aoshima; Kazuyoshi Sasaoka; Ryohei Kinoshita; Atsushi Kobayashi; Mitsuyoshi Takiguchi; Takashi Kimura
  Journal of veterinary diagnostic investigation, 34, 1, 94, 97, 04 Sep. 2021, [Peer-reviewed], [International Magazine]
  English, Scientific journal, A 27-mo-old, spayed female mixed-breed dog was presented with left forelimb pain, which progressed to full thickness necrosis of the soft tissues of multiple limbs. Clinical imaging and postmortem examination suggested multiple large arterial thromboemboli. Histologic examination of vascular lesions revealed markedly thickened tunica intima with polypoid intraluminal projections, which partially to entirely occluded the arterial lumen. The expanded tunica intima was comprised of intimal accumulation of Alcian blue-positive matrix with scattered spindle-to-satellite cells. These cells were positive for von Willebrand factor and vimentin but negative for α-smooth muscle actin, suggesting endothelial origin. Deposition of the intimal mucoid matrix was observed in the elastic and muscular arteries associated with regional ischemic changes. Mucoid emboli, likely from fragmentation of proliferative intimal tissue, were identified in smaller vessels supplied by affected arteries. Based on these findings, we diagnosed systemic mucoid degeneration of the arterial tunica intima. Such systemic arterial degeneration characterized by deposition of mucoid matrix in the tunica intima has not been reported previously in dogs, to our knowledge, and should be distinguished from thromboembolism and other degenerative vascular diseases.
• Simultaneous steroids measurement in dogs with hyperadrenocorticism using a column-switching liquid chromatography-tandem mass spectrometry method.
  Noboru Sasaki; Thandar Oo; Yoshikazu Yasuda; Takahiro Ichise; Noriyuki Nagata; Nozomu Yokoyama; Kazuyoshi Sasaoka; Keitaro Morishita; Shouta Mm Nakayama; Mayumi Ishizuka; Kensuke Nakamura; Mitsuyoshi Takiguchi; Yoshinori Ikenaka
  The Journal of veterinary medical science, 83, 11, 1634, 1642, Sep. 2021, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, We developed an analytical method using an on-line column-switching liquid chromatography with triple quadrupole mass spectrometry (LC/MS/MS) for quantifying multiple steroids in serum. Using the developed method, we evaluated the serum concentration of nine steroids (cortisol, corticosterone, cortisone, 11-deoxycortisol, 21-deoxycortisol, deoxycorticosterone, progesterone, 17α-OH-progesterone and aldosterone) in dogs with hyperadrenocorticism (HAC). Serum was mixed with stable isotope internal standards and thereafter purified by the automated column-switching system. The limit of detection ranged 2-16 pg/ml for nine steroids. In the baseline samples, five steroids (cortisol, corticosterone, cortisone, 11-deoxycortisol, and 17α-OH-progesterone) were detected in all dogs. The concentrations of cortisone, 11-deoxycortisol, and 17α-OH-progesterone in dogs with HAC (n=19) were significantly higher those in dogs without HAC (n=15, P<0.02). After the adrenocorticotropic hormone stimulation test, six steroids (cortisol, corticosterone, cortisone, 11-deoxycortisol, 17α-OH-progesterone, and deoxycorticosterone) were above the limit of quantification in all dogs. Cortisol, corticosterone, cortisone, and deoxycorticosterone concentrations of dogs with HAC were significantly higher than those of dogs without HAC (P<0.02). In addition, 11-deoxycortisol and 17α-OH-progesterone concentration was higher in dogs with HAC than in dogs without HAC (P=0.044 and P=0.048, respectively). The on-line column-switching LC/MS/MS would be feasible for measuring multiple steroids in dog serum. The results suggest that cortisone, 11-deoxycortisol, and 17α-OH-progesterone would be related to HAC. Further studies are warranted to assess the clinical feasibility of steroid profile in dogs with HAC.
• The effects of fipronil on emotional and cognitive behaviors in mammals
  Tomohiro Suzuki; Anri Hirai; Kraisiri Khidkhan; Collins Nimako; Takahiro Ichise; Kazuki Takeda; Hazuki Mizukawa; Shouta M.M. Nakayama; Kei Nomiyama; Nobuhiko Hoshi; Mizuki Maeda; Tetsushi Hirano; Kazuyoshi Sasaoka; Noboru Sasaki; Mitsuyoshi Takiguchi; Mayumi Ishizuka; Yoshinori Ikenaka
  Pesticide Biochemistry and Physiology, 175, 104847, 104847, Elsevier BV, Jun. 2021, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Fipronil is a phenylpyrazole insecticide that is widely used as a pesticide and a veterinary drug, although studies suggest that it could be toxic to mammals. The objectives of this study were to examine the pharmacokinetic profile of fipronil in mice, dogs, and cats, and to evaluate its effects on emotional and cognitive behaviors of dogs and cats using the data obtained from mice. The assessment of in vivo kinetics of fipronil was conducted in mice and dogs. We also performed behavioral tests (elevated plus-maze and Y-maze) and measured the levels of neurotransmitters in mice exposed to fipronil. In addition, the in vitro metabolism of fipronil were evaluated using liver microsomes of rats, mice, dogs, and cats. The results revealed that fipronil is distributed throughout the body (blood, brain, adipose tissue, and liver) of mice after dermal application. It was metabolized to fipronil sulfone primarily in the liver. The data on kinetics show that both fipronil and fipronil sulfone have a longer half-life in dogs and cats than in mice. The behavioral tests indicated that fipronil and fipronil sulfone could affect emotional and cognitive behaviors and alter the levels of neurotransmitters (dopamine in the striatum and serotonin in the hippocampus) in mice. Furthermore, we found that dogs and cats have a low ability to metabolize fipronil than mice and rats. However, further comprehensive studies are needed to determine whether fipronil affects the emotional and cognitive behaviors when administered to dogs and cats. To the best of our knowledge, this is the first study to examine the pharmacokinetic data and verify the effects of fipronil on emotional and cognitive behaviors of dogs and cats using the data obtained from mice.
• Acute effects of intravenous pimobendan administration in dog models of chronic precapillary pulmonary hypertension
  T. Morita; K. Nakamura; T. Osuga; S. Kawamoto; S. Miki; K. Sasaoka; M. Takiguchi
  Journal of Veterinary Cardiology, 32, 16, 27, Dec. 2020, [Peer-reviewed]
  Scientific journal
• An area ratio of thyroid gland to common carotid artery for evaluating the thyroid gland size.
  Noboru Sasaki; Noriyuki Nagata; Keitaro Morishita; Tatsuyuki Osuga; Kazuyoshi Sasaoka; Nozomu Yokoyama; Hiroshi Ohta; Mitsuyoshi Takiguchi
  The Journal of veterinary medical science, 82, 7, 1012, 1016, 31 Jul. 2020, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, The feasibility of ultrasonographic measurement of thyroid gland area to common carotid artery (TG:CCA) was investigated. Twenty-one healthy, 12 hypothyroid and 18 non-thyroid illness (NTI) dogs were evaluated. The area of thyroid lobe and common carotid artery in right and left sides were measured using the same ultrasonographic images in transverse plane. The average of the right and left ratio was calculated as TG:CCA. The median TG:CCA of 21 healthy dogs was 1.53, and it did not correlate either body weight or age. The median TG:CCA of 12 hypothyroid dogs was 0.81, which was significantly lower than that of 18 NTI dogs (1.81, P<0.001). If the cut off value <1.12 was used, TG:CCA indicated hypothyroidism with a sensitivity of 100%, specificity of 83%, and accuracy of 90%. Our data indicated that TG:CCA was independent of both body weight, which may contribute to consistent measurement of thyroid size. The results of this study suggest that TG:CCA is a promising tool for diagnosing canine hypothyroidism.
• Endothelial Cells, First Target of Drug Delivery Using Microbubble-Assisted Ultrasound.
  Antoine Presset; Corentin Bonneau; Sasaoka Kazuyoshi; Lydie Nadal-Desbarats; Takigucho Mitsuyoshi; Ayache Bouakaz; Nobuki Kudo; Jean-Michel Escoffre; Noboru Sasaki
  Ultrasound in medicine & biology, 46, 7, 1565, 1583, Jul. 2020, [International Magazine]
  English, Scientific journal, Microbubble-assisted ultrasound has emerged as a promising method for local drug delivery. Microbubbles are intravenously injected and locally activated by ultrasound, thus increasing the permeability of vascular endothelium for facilitating extravasation and drug uptake into the treated tissue. Thereby, endothelial cells are the first target of the effects of ultrasound-driven microbubbles. In this review, the in vitro and in vivo bioeffects of this method on endothelial cells are described and discussed, including aspects on the permeabilization of biologic barriers (endothelial cell plasma membranes and endothelial barriers), the restoration of their integrity, the molecular and cellular mechanisms involved in both these processes, and the resulting intracellular and intercellular consequences. Finally, the influence of the acoustic settings, microbubble parameters, treatment schedules and flow parameters on these bioeffects are also reviewed.
• Effect of ultra low fat diet on regulatory T cells of dogs with intestinal limphangiectasia secondary to chronic enteropathy: A pilot study
  Nisa K; Ohta H; Yokoyama N; Tamura M; Nagata N; Sasaoka K; Dermlim A; Leela-Arporn R; Morita T; Osuga T; Sasaki N; Morishita K; Nakamura K; Kagawa Y; Takiguchi M
  The Japanese journal of veterinary research, 67, 3, 221, 227, Aug. 2019, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal
• Effect of acute volume loading on left atrial strain values derived from two-dimensional speckle tracking echocardiography in dogs.
  Angkhana Dermlim; Tatsuyuki Osuga; Kensuke Nakamura; Tomoya Morita; Khoirun Nisa; Kazuyoshi Sasaoka; Rommaneeya Leela-Arporn; Noriyuki Nagata; Masahiro Tamura; Noboru Sasaki; Hiroshi Ohta; Mitsuyoshi Takiguchi
  The Journal of veterinary medical science, 81, 7, 949, 957, 11 Jul. 2019, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, The purpose of this study was to evaluate the cardiac acute volume loading effect on left atrial (LA) strain and strain rate (SR) parameters derived from two-dimensional speckle tracking echocardiography (2D-STE) in healthy dogs. Six healthy beagles were anesthetized and subjected to increase cardiac preload by intravenous infusion with lactated Ringer solution at 150 ml/kg/hr for 90 min. A Swan-Ganz catheter was placed to directly measure the mean pulmonary capillary wedge pressure (PCWP). Echocardiography was performed before (baseline) and at 15, 30, 45, 60, 75, and 90 min after acute volume loading began. Apical 4-chamber images focused on the LA were digitally recorded for later strain and SR analysis via 2D-STE. Acute volume loading significantly increased from baseline during LA strain and SR as assessed by the speckle tracking-based technique during reservoir and conduit function at 15 to 90 min after volume load began, and strain indices representing booster pump function were enhanced at 45 to 90 min. In addition, acute volume loading resulted in a significantly greater PCWP after fluid infusion. On multiple regression analysis, quadratic regression analysis was a better fit for the relationship between PCWP and all LA functional indices. Our findings indicated that LA function analyzed by strain and SR was enhanced during cardiac acute volume loading in healthy dogs. The change in strain and SR during acute volume loading should be interpreted with caution during the diagnosis of heart diseases related to volume overload.
• Plasma-free amino acid profiles in dogs with hepatocellular carcinoma.
  Rommaneeya Leela-Arporn; Hiroshi Ohta; Masahiro Tamura; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Khoirun Nisa; Tatsuyuki Osuga; Keitaro Morishita; Noboru Sasaki; Mitsuyoshi Takiguchi
  Journal of veterinary internal medicine, 33, 4, 1653, 1659, Jul. 2019, [Peer-reviewed], [International Magazine]
  English, Scientific journal, BACKGROUND: Metabolomic analysis using blood samples has been suggested to be useful for the early detection of cancer. Among metabolites, plasma-free amino acid (PFAA) profiles are potential diagnostic biomarkers for several diseases including cancer. However, the relationship between PFAA concentrations and liver tumors in dogs remains unknown. OBJECTIVE: To determine the characteristics of PFAA profiles of dogs with hepatocellular carcinoma (HCC) and correlated clinical features. ANIMALS: Thirty-four client-owned dogs diagnosed with HCC (n = 26) and benign liver diseases (n = 8) and 11 age-matched healthy dogs. METHODS: Prospective study using heparinized blood samples from fasted dogs. Plasma was deproteinized, and the concentrations of 21 amino acids were measured using an automated high-performance liquid chromatography amino acid analyzer. RESULTS: Plasma glutamic acid concentrations were significantly different among groups (P < .0024 after Bonferroni correction). Compared to healthy dogs, dogs with HCC and benign liver diseases had significantly higher concentrations of glutamic acid by post hoc analysis. However, no significant difference in the PFAA profiles of HCC and benign liver diseases were detected. In addition, preoperative and postoperative PFAA profiles of dogs with HCC were not significantly different. CONCLUSIONS AND CLINICAL IMPORTANCE: Increased glutamic acid concentrations might play a role in the development or be a consequence of liver tumor formation. However, PFAA profiles of HCC could not be differentiated from those of benign lesions. In addition, glutamic acid concentrations did not change after surgical resection. These results indicate that PFAA profiles may not be useful biomarkers for detecting HCC in dogs.
• Epidemiology of massive hepatocellular carcinoma in dogs: A 4-year retrospective study.
  Leela-Arporn R; Ohta H; Nagata N; Sasaoka K; Tamura M; Dermlim A; Nisa K; Morishita K; Sasaki N; Nakamura K; Takagi S; Hosoya K; Takiguchi M
  Veterinary journal (London, England : 1997), 248, 74, 78, Elsevier BV, Jun. 2019, [Peer-reviewed], [International Magazine]
  Scientific journal
• The Repeatability and Left Atrial Strain Analysis Obtained via Speckle Tracking Echocardiography in healthy Dogs.
  Dermlim A; Nakamura K; Morita T; Osuga T; Nisa K; Sasaoka K; Leela-arporn R; Sasaki N; Ohta H; Takiguchi M
  Journal of Veterinary Cardiology, 23, 69, 80, Elsevier BV, Jun. 2019, [Peer-reviewed], [International Magazine]
  English, Scientific journal
• Predictive factors of malignancy in dogs with focal liver lesions using clinical data and ultrasonographic features.
  Rommaneeya Leela-Arporn; Hiroshi Ohta; Masahiro Tamura; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Khoirun Nisa; Keitaro Morishita; Noboru Sasaki; Kensuke Nakamura; Satoshi Takagi; Kenji Hosoya; Mitsuyoshi Takiguchi
  The Journal of veterinary medical science, 81, 5, 723, 729, 31 May 2019, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, A definitive diagnosis of focal liver lesions (FLLs) requires invasive procedures for histopathologic examination. Thus, a simpler noninvasive diagnostic method, such as conventional ultrasonography combined with clinical data, is needed for the prediction of liver malignancy. The objective of this study was to examine the diagnostic accuracy of clinical data and ultrasonographic (US) features to differentiate benign and malignant liver lesions. Medical records and US images from dogs with FLLs that underwent abdominal US and histopathologic examinations following surgery or liver biopsy were retrospectively reviewed. Clinical data, including signalment, clinical signs and laboratory findings, and the US features of liver lesions that could act as predictive factors were assessed using univariate and multivariate analyses to evaluate the associations between predictive factors and liver malignancy. Based on the histopathologic results, 55 dogs with malignant lesions and 28 dogs with benign lesions were included in the study. The results of univariate analysis showed that several US features and platelet count were significantly associated with liver malignancy. Multivariate analysis revealed that the platelet count (thrombocytosis; odds ratio [OR]: 4.13, 95% confidence intervals [CI]: 1.81-9.41), lesion size (4.1 cm or greater; OR: 23.83, 95% CI: 3.74-151.95) and echotexture of FLLs (heterogenous; OR: 8.44; 95% CI: 1.37-51.91) were independent predictors for differentiating benign and malignant liver lesions, suggesting that a combination of clinical data and US findings of FLLs could predict liver malignancy in dogs.
• Evaluation of duodenal perfusion by contrast-enhanced ultrasonography in dogs with chronic inflammatory enteropathy and intestinal lymphoma.
  Khoirun Nisa; Sue Yee Lim; Masayoshi Shinohara; Tatsuyuki Osuga; Nozomu Yokoyama; Masahiro Tamura; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Rommaneeya Leela-Arporn; Tomoya Morita; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hiroshi Ohta; Mitsuyoshi Takiguchi
  Journal of veterinary internal medicine, 33, 2, 559, 568, Mar. 2019, [Peer-reviewed], [International Magazine]
  English, Scientific journal, BACKGROUND: Contrast-enhanced ultrasonography (CEUS) can be used to evaluate intestinal perfusion in healthy dogs. It is helpful for diagnosing and monitoring inflammatory bowel disease in humans and could be useful for dogs with chronic intestinal diseases. OBJECTIVES: To examine duodenal perfusion in dogs with chronic inflammatory enteropathy (CIE) and intestinal lymphoma. ANIMALS: Client-owned dogs with CIE (n = 26) or intestinal lymphoma (n = 7) and dogs with gastrointestinal signs but histopathologically normal duodenum (controls, n = 14). METHODS: In this cross-sectional study, dogs with CIE were classified into remission (n = 16) and symptomatic (n = 10) groups based on clinical scores determined at the time of CEUS. The duodenum was scanned after IV injection of Sonazoid® (0.01 mL/kg). CEUS-derived perfusion parameters, including time-to-peak, peak intensity (PI), area under the curve (AUC), and wash-in and wash-out rates were evaluated. RESULTS: The PI was significantly higher in the symptomatic CIE group (median (range); 105.4 (89.3-128.8) MPV) than in the control group (89.9 (68.5-112.2) MPV). The AUC was significantly higher in the symptomatic CIE group (4847.9 (3824.3-8462.8) MPV.sec) than in the control (3448.9 (1559.5-4736.9) MPV.sec) and remission CIE (3862.3 (2094.5-6899.0) MPV.sec) groups. The PI and clinical score were positively correlated in the CIE group. No significant differences in perfusion parameters were detected between the lymphoma and CIE groups or the lymphoma and control groups. CONCLUSIONS AND CLINICAL IMPORTANCE: The PI and AUC can detect duodenal inflammation and hence are potentially useful for excluding a diagnosis of CIE.
• The effect of sedation with a combination of butorphanol and midazolam on quantitative contrast-enhanced ultrasonography of duodenum in healthy dogs.
  Khoirun Nisa; Sue Yee Lim; Tatsuyuki Osuga; Nozomu Yokoyama; Masahiro Tamura; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Rommaneeya Leela-Arporn; Tomoya Morita; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hiroshi Ohta; Mitsuyoshi Takiguchi
  The Journal of veterinary medical science, 80, 3, 453, 459, 24 Mar. 2018, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal
• Transcranial Doppler Ultrasound Examination in Dogs with Suspected Intracranial Hypertension Caused by Neurologic Diseases
  K. Sasaoka; K. Nakamura; T. Osuga; T. Morita; N. Yokoyama; K. Morishita; N. Sasaki; H. Ohta; M. Takiguchi
  Journal of Veterinary Internal Medicine, 32, 1, 314, 323, Blackwell Publishing Inc., 01 Jan. 2018, [Peer-reviewed], [Lead author], [International Magazine]
  English, Scientific journal, 13227273
• Repeatability and reproducibility of quantitative contrast-enhanced ultrasonography for assessing duodenal perfusion in healthy dogs.
  Khoirun Nisa; Sue Yee Lim; Masayoshi Shinohara; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Rommaneeya Leela-Arporn; Tomoya Morita; Nozomu Yokoyama; Tatsuyuki Osuga; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hiroshi Ohta; Mitsuyoshi Takiguchi
  The Journal of veterinary medical science, 79, 9, 1585, 1590, 29 Sep. 2017, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, Contrast-enhanced ultrasonography (CEUS) with microbubbles as a contrast agent allows the visualization and quantification of tissue perfusion. The assessment of canine intestinal perfusion by quantitative CEUS may provide valuable information for diagnosing and monitoring chronic intestinal disorders. This study aimed to assess the repeatability (intraday variability) and reproducibility (interday variability) of quantitative duodenal CEUS in healthy dogs. Six healthy beagles underwent CEUS three times within one day (4-hr intervals) and on two different days (1-week interval). All dogs were sedated with a combination of butorphanol (0.2 mg/kg) and midazolam (0.1 mg/kg) prior to CEUS. The contrast agent (Sonazoid®) was administered using the intravenous bolus method (0.01 ml/kg) for imaging of the duodenum. Time-intensity curves (TIC) were created by drawing multiple regions of interest (ROIs) in the duodenal mucosa, and perfusion parameters, including the time-to-peak (TTP), peak intensity (PI), area under the curve (AUC), and wash-in and wash-out rates (WiR and WoR, respectively), were generated. Intraday and interday coefficients of variation (CVs) for TTP, PI, AUC, WiR and WoR were <25% (range, 2.27-23.41%), which indicated that CEUS was feasible for assessing duodenal perfusion in healthy sedated dogs. A further study of CEUS in dogs with chronic intestinal disorders is necessary to evaluate its clinical applicability.
• Two Feline Cases of Dilated Cardiomyopathy-Like Disease Caused by Feline Infectious Peritonitis Virus.
  Yoshida T; Ichikawa N; Koike M; Hirokawa T; Sasaoka K; Machida N; Taguchi M
  Journal of Animal Clinical Medicine, 25, 4, 148, 152, Sep. 2016, [Peer-reviewed], [Domestic magazines]
  Japanese, Scientific journal
• Clinical usefulness of Transcranial Doppler ultrasound in dogs.
  Kazusyohi Sasaoka
  Japanese Journal of Veterinary Research, 61, 51, 52, 2013, [Lead author], [Domestic magazines]
  English

• General Internal Medicine Guidelines: Anorexia “A Dog with a Macro Pituitary Tumor Presenting with Anorexia”
  Kazuyoshi Sasaoka, Small Animal Internal Medicine, 3, 2, 28, 33, Apr. 2026, [Invited], [Lead author], [Domestic magazines]
  EDUWARD Press, Japanese, Introduction commerce magazine
• Understanding Encephalitis: Part 4 – Prognosis of Meningoencephalomyelitis of Unknown Origin (MUO) and Feline MUO
  Kazuyoshi Sasaoka, JSAVA NEWS, 188, 13, 25, Mar. 2026, [Invited], [Lead author, Corresponding author], [Domestic magazines]
  Japan Small Animal Veterinary Association, Japanese, Introduction commerce magazine
• Understanding Encephalitis: Part 3 – The Treatment of Meningoencephalomyelitis of Unknown Origin (MUO)
  Kazuyoshi Sasaoka, JSAVA NEWS, 187, 19, 27, Jan. 2026, [Invited], [Lead author, Corresponding author], [Domestic magazines]
  Japan Small Animal Veterinary Association, Japanese, Introduction commerce magazine
• Clinical Reasoning in Neurology: Tremors
  Kazuyoshi Sasaoka, Daisuke Ito, Small Animal Internal Medicine, 2, 5, 55, 65, Oct. 2025, [Invited], [Lead author], [Domestic magazines]
  EDUWARD Press, Japanese, Introduction commerce magazine
• Practical Tips for Selecting Among Drugs: Neurology – Maintenance-Phase Antiepileptic Drugs (Part 2)
  Kazuyoshi Sasaoka; Daisuke Ito, CAP: Companion Animal Practice, 40, 10, 62, 69, Oct. 2025, [Invited], [Lead author], [Domestic magazines]
  Midori Shobo, Japanese, Introduction commerce magazine
• Understanding Encephalitis: Part 2 – Diagnostic Criteria and Practical Diagnosis of Meningoencephalomyelitis of Unknown Origin (MUO)
  Kazuyoshi Sasaoka, JSAVA NEWS, 186, 14, 21, Oct. 2025, [Invited], [Lead author, Corresponding author], [Domestic magazines]
  Japan Small Animal Veterinary Association
• Practical Tips for Selecting Among Drugs: Neurology – Maintenance-Phase Antiepileptic Drugs (Part 1)
  Kazuyoshi Sasaoka; Daisuke Ito, CAP: Companion Animal Practice, 40, 9, 62, 68, Sep. 2025, [Invited], [Lead author], [Domestic magazines]
  Midori Shobo, Japanese, Introduction commerce magazine
• Understanding Encephalitis: Part 1 – The Background Behind the Emergence of Meningoencephalomyelitis of Unknown Origin (MUO)
  Kazuyoshi Sasaoka, JSAVA NEWS, 185, 30, 36, Jul. 2025, [Invited], [Lead author, Corresponding author]
  Japan Small Animal Veterinary Association, Japanese, Introduction commerce magazine
• 獣医師生涯研修事業 Q&A小動物編
  日本獣医師会雑誌, 78, 4, 147, 149, Apr. 2025, [Invited], [Lead author, Corresponding author]
  Japanese, Introduction scientific journal
• 意識障害は起源不明髄膜脳脊髄炎(MUO)の予後不良に関連する MUO82例の回顧的検討(2014～2022)
  笹岡 一慶; 福家 知樹; 須永 隆文; 大田 寛; 滝口 満喜, 北海道獣医師会雑誌, 68, 8, 313, 313, Aug. 2024
  (公社)北海道獣医師会, Japanese
• ラブラドール・レトリーバーのコロニーで集団発生したサルファ剤過敏症とCYPB5Rの遺伝子型頻度解析
  岸原 果子; 横山 望; 山崎 淳平; 笹岡 一慶; 森下 啓太郎; 中村 健介; 宮原 和郎; 近藤 厚; 滝口 満喜; 高橋 徹, 北海道獣医師会雑誌, 68, 8, 314, 314, Aug. 2024
  (公社)北海道獣医師会, Japanese
• I’d Like to Ask About Client Communication: Episode 1 – Idiopathic Epilepsy
  Kazuyoshi Sasaoka, CAP: Companion Animal Practice, 39, 7, 44, 49, Jul. 2024, [Invited], [Lead author], [Domestic magazines]
  Midori Shobo, Japanese, Introduction commerce magazine
• 猫の画像診断を究める「MRI診断を究める」
  笹岡一慶, Felis フェーリス Journal of Feline Practice, 20, 81, 100, Feb. 2024, [Lead author], [Domestic magazines]
  Japanese, Introduction commerce magazine
• 猫の心筋症における左房ブースターストレインの有用性の検討
  佐藤景; 中村健介; 川元誠; 菅原芽伊; 笹岡一慶; 横山望; 佐々木東; 森下啓太郎; 滝口満喜, 日本獣医循環器学会抄録(CD-ROM), 121st, 2024
• 標準的感染症対策プログラムは動物病院において手指衛生コンプライアンス向上と多剤耐性菌出現抑制に貢献する
  笹岡 一慶; 森下 啓太郎; 細谷 謙次; 佐藤 敬近; 佐藤 豊孝; 堀内 基広; 滝口 満喜, 日本獣医学会学術集会講演要旨集, 166回, 174, 174, Sep. 2023
  (公社)日本獣医学会, Japanese
• こんなところにも超音波検査「脳」
  笹岡一慶, 月刊CAP: Companion Animal Practice, 38, 6, 8, 17, Jun. 2023, [Lead author]
• 獣医師生涯研修事業 Q&A小動物編
  笹岡一慶, 日本獣医師会雑誌, 76, 3, 179, 181, Mar. 2023, [Invited], [Lead author]
  Japanese, Introduction commerce magazine
• 犬の発作性ジスキネジア23例の回顧的検討
  川上侑記; 笹岡一慶; 大田寛; 山根由久; 新坊弦也; 横山望; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜, 北海道獣医師会雑誌, 67, 8, 2023
• この症例あなたならどうする？「発作の続く特発性てんかん症例」
  笹岡一慶, 月刊CAP: Companion Animal Practice, 37, 12, 72, 77, Dec. 2022
• 2次診療動物病院に来院した犬の糞便真核生物叢解析
  横山 望; 川口 剛; 中尾 亮; 森下 啓太郎; 細谷 謙次; 永田 矩之; 笹岡 一慶; 新坊 弦也; 佐々木 東; 中村 健介; 滝口 満喜, 日本獣医学会学術集会講演要旨集, 165回, [HS1P, 16], Sep. 2022
  (公社)日本獣医学会, Japanese
• 磁気共鳴スペクトロスコピーは犬の起源不明髄膜脳脊髄炎の予後指標となり得るか
  山口 敬央; 笹岡 一慶; 新坊 弦也; 山根 由久; 永田 矩之; 横山 望; 森下 啓太郎; 佐々木 東; 中村 健介; 滝口 満喜, 北海道獣医師会雑誌, 66, 8, 287, 287, Aug. 2022
  (公社)北海道獣医師会, Japanese
• 院内湿潤環境に対する注意喚起 北大附属動物病院における環境サーベイランス結果
  笹岡 一慶; 新田 優里香; 佐藤 豊孝; 堀内 基広; 滝口 満喜, 北海道獣医師会雑誌, 66, 8, 287, 287, Aug. 2022
  (公社)北海道獣医師会, Japanese
• 洞停止を認めた咳嗽失神の犬の1例
  幸野 瑠美; 中村 健介; 笹岡 一慶; 塩原 希; 小幡 祐路; 滝口 満喜, 北海道獣医師会雑誌, 66, 8, 284, 284, Aug. 2022
  (公社)北海道獣医師会, Japanese
• 犬尿中コルチゾール/クレアチニン比の基準値の確立とクッシング症候群の診断への応用
  永田 矩之; 澤村 飛龍; 五日市 大介; 森下 啓太郎; 細谷 謙次; 横山 望; 笹岡 一慶; 佐々木 東; 中村 健介; 池中 良徳; 滝口 満喜, 北海道獣医師会雑誌, 66, 8, 286, 286, Aug. 2022
  (公社)北海道獣医師会, Japanese
• 磁気共鳴スペクトロスコピーは犬の起源不明髄膜脳脊髄炎の予後指標となり得るか
  山口 敬央; 笹岡 一慶; 新坊 弦也; 山根 由久; 永田 矩之; 横山 望; 森下 啓太郎; 佐々木 東; 中村 健介; 滝口 満喜, 北海道獣医師会雑誌, 66, 8, 287, 287, Aug. 2022
  (公社)北海道獣医師会, Japanese
• 低コレステロール血症は犬の膵外分泌不全を予測できるのか?
  横山 望; 大田 寛; 永田 矩之; 笹岡 一慶; 新坊 弦也; 佐々木 東; 森下 啓太郎; 中村 健介; 滝口 満喜, 北海道獣医師会雑誌, 66, 8, 284, 284, Aug. 2022
  (公社)北海道獣医師会, Japanese
• 院内湿潤環境に対する注意喚起 北大附属動物病院における環境サーベイランス結果
  笹岡 一慶; 新田 優里香; 佐藤 豊孝; 堀内 基広; 滝口 満喜, 北海道獣医師会雑誌, 66, 8, 287, 287, Aug. 2022
  (公社)北海道獣医師会, Japanese
• Analysis of variation of serum metabolites in cats by BDE209 long-term exposure test using Smart Metabolite Database
  野見山桂; 林多聞; 江口哲史; 水川葉月; 高口倖暉; 横山望; 市居修; 滝口満喜; 笹岡一慶; 中山翔太; 池中良徳; 石塚真由美; 国末達也, 環境化学討論会要旨集(CD-ROM), 29th, 2021
• 私の心に残るあの症例「てんかん重積状態を集中管理で乗り切った脳炎症例」
  笹岡 一慶, 月刊CAP: Companion Animal Practice, 35, 12, 72, 78, Dec. 2020
  (株)緑書房, Japanese
• 体内動態および行動毒性試験から見た動物用医薬品フィプロニルの影響評価
  鈴木智裕; 池中良徳; 中山翔太; 水川葉月; 一瀬貴大; 佐々木東; 笹岡一慶; 石塚真由美, 日本獣医学会学術集会講演要旨集, 162nd, 501, 501, 20 Aug. 2019
  (公社)日本獣医学会, Japanese
• 詳細な病理学的解析に基づいて治療方針を決定した免疫複合体性糸球体腎炎の犬の1例
  新井田 篤; 大田 寛; 笹岡 一慶; 細谷 謙次; 市居 修; 賀川 由美子; 大菅 辰幸; 佐々木 東; 森下 啓太郎; 滝口 満喜, 北海道獣医師会雑誌, 63, 8, 336, 336, Aug. 2019
  (公社)北海道獣医師会, Japanese
• 犬の僧帽弁疾患における2D Speckle Tracking心エコー図法を用いた左心房stiffnessの推定
  黒田 杏子; 大菅 辰幸; 笹岡 一慶; 森下 啓太郎; 佐々木 東; 大田 寛; 滝口 満喜, 日本獣医学会学術集会講演要旨集, 162回, 464, 464, Aug. 2019
  (公社)日本獣医学会, Japanese
• 猫の新規炎症マーカー、ロイシンリッチα2糖蛋白質(LRG)の測定系構築の試み
  坂本 暁彦; 大田 寛; 好井 健太朗; 矢吹 悠久美; 笹岡 一慶; 大菅 辰幸; 佐々木 東; 森下 啓太郎; 滝口 満喜, 日本獣医学会学術集会講演要旨集, 162回, 475, 475, Aug. 2019
  (公社)日本獣医学会, Japanese
• LC‐MS/MSを用いたイヌ尿中メタネフリンおよびノルメタネフリン測定
  井上裕美子; 佐々木東; 池中良徳; 一瀬貴大; 笹岡一慶; 大菅辰幸; 中山翔太; 森下啓太郎; 大田寛; 石塚真由美; 滝口満喜, 日本獣医学会学術集会講演要旨集, 162回, 470, 470, Aug. 2019
  (公社)日本獣医学会, Japanese
• 小動物の神経疾患に対する超音波検査の応用
  笹岡 一慶, MPアグロジャーナル, 38, 38, 14, 17, Jul. 2019
  MPアグロ, Japanese, Introduction commerce magazine
• デカブロモジフェニルエーテル(BDE209)の長期曝露がイエネコへ及ぼす影響
  田中啓介; 野見山桂; 水川葉月; 水川葉月; 高口倖暉; 田上瑠美; 横山望; 市居修; 滝口満喜; 笹岡一慶; 中山翔太; 池中良徳; 石塚真由美; 国末達也; 田辺信介, 環境化学討論会要旨集(CD-ROM), 28th, ROMBUNNO.1C‐09, 11 Jun. 2019
  Japanese
• ロンドン大学王立獣医科大学神経・神経外科での短期留学をおえて
  笹岡 一慶, 月刊CAP: Companion Animal Practice, 359, 104, 107, May 2019
  Japanese, Introduction commerce magazine
• ロジックで学ぶ 犬と猫の臨床テクニック 第15回 脳脊髄液を安全に採取する
  笹岡一慶; 大田寛, 月刊CAP: Companion Animal Practice, 356, 108‐115, Feb. 2019
  Japanese, Introduction commerce magazine
• 猫の疾患|総まとめ(前編)猫の糖尿病,糖尿病性ケトアシドーシスをまとめ直す
  笹岡一慶, Clinic Note, 15, 1, 54, 64, Jan. 2019
  Japanese, Introduction commerce magazine
• 神経筋接合部検査としてアイスパックテストを試みた重症筋無力症の犬の1例
  山田 有紗; 笹岡 一慶; 大田 寛; 立花 由莉加; 大菅 辰幸; 佐々木 東; 森下 啓太郎; 滝口 満喜, 北海道獣医師会雑誌, 62, 8, 335, 335, Aug. 2018
  (公社)北海道獣医師会, Japanese
• 神経症状を主訴とした悪性中皮腫の猫の1例
  大村 侑己; 大田 寛; 小林 篤史; 笹岡 一慶; 道下 明日香; 大菅 辰幸; 佐々木 東; 森下 啓太郎; 滝口 満喜, 北海道獣医師会雑誌, 62, 8, 340, 340, Aug. 2018
  (公社)北海道獣医師会, Japanese
• 経頭蓋超音波ドプラ法により局所的な脳循環動態を評価し得た右中大脳動脈梗塞の犬の1例
  笹岡 一慶; 大田 寛; 石塚 友人; 大菅 辰幸; 立花 由莉加; 森下 啓太郎; 佐々木 東; 滝口 満喜, 北海道獣医師会雑誌, 62, 8, 341, 341, Aug. 2018
  (公社)北海道獣医師会, Japanese
• 健康な犬における二次元スペックルトラッキング心エコーによる左心室長軸方向ストレイン解析に与える心臓容積負荷の影響(Effect of cardiac volume loading on left atrial longitudinal strain analysis derived from two-dimensional Speckle Tracking Echocardiography in healthy dogs)
  Dermlim Angkhana; 中村 健介; 森田 智也; 大菅 辰幸; Nisa Khoirun; Leela-arporn Rommaneeya; 笹岡 一慶; 永田 矩之; 田村 昌大; 佐々木 東; 大田 寛; 森下 啓太郎; 滝口 満喜, 日本獣医学会学術集会講演要旨集, 161回, 435, 435, Aug. 2018
  (公社)日本獣医学会, English
• 神経筋接合部検査としてアイスパックテストを試みた重症筋無力症の犬の1例
  山田有紗; 笹岡一慶; 大田寛; 立花由莉加; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜, 北海道獣医師会雑誌, 62, 8, 335, 335, Aug. 2018
  (公社)北海道獣医師会, Japanese
• 経頭蓋超音波ドプラ法により局所的な脳循環動態を評価し得た右中大脳動脈梗塞の犬の1例
  笹岡一慶; 大田寛; 石塚友人; 大菅辰幸; 立花由莉加; 森下啓太郎; 佐々木東; 滝口満喜, 北海道獣医師会雑誌, 62, 8, 341, 341, Aug. 2018
  (公社)北海道獣医師会, Japanese
• 神経症状を主訴とした悪性中皮腫の猫の1例
  大村侑己; 大田寛; 小林篤史; 笹岡一慶; 道下明日香; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜, 北海道獣医師会雑誌, 62, 8, 340, 340, Aug. 2018
  (公社)北海道獣医師会, Japanese
• 有機ハロゲン化合物曝露によるネコの生化学マーカーの変化および甲状腺機能に及ぼす影響評価
  水川葉月; KHIDKHAN Kraisiri; 高口倖暉; 横山望; 市居修; 滝口満喜; 笹岡一慶; 池中良徳; 池中良徳; 中山翔太; TSEND‐AYUSH Sainnoxoi; 野見山桂; 田辺信介; 石塚真由美, 環境化学討論会要旨集(CD-ROM), 27th, ROMBUNNO.2A‐10, 11 May 2018
  Japanese
• ネコのin vivo BDE209長期曝露試験による体内動態の解明および甲状腺ホルモンへの影響評価
  田中啓介; 野見山桂; 水川葉月; 高口倖暉; 田上瑠美; 横山望; 市居修; 滝口満喜; 笹岡一慶; 中山翔太; 池中良徳; 石塚真由美; 国末達也; 田辺信介, 環境化学討論会要旨集(CD-ROM), 27th, ROMBUNNO.1A‐03(PA‐13), 11 May 2018
  Japanese
• 不明熱の診断プロセス:ケースレポート 4)腸管の化膿性肉芽腫と多発性関節炎を併発し発熱を呈した犬の1例
  笹岡一慶, Clinic Note, 13, 12, 39, 45, Dec. 2017
  Japanese, Introduction commerce magazine
• 犬慢性腸症の十二指腸粘膜におけるロイシンリッチα2糖蛋白の発現とその臨床的意義
  奥朋哉; 大田寛; 田村昌大; 永田矩之; 笹岡一慶; LEELA‐ARPORN Rommaneeya; DERMLIM Angkhana; NISA Khoirun; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜, 日本獣医学会学術集会講演要旨集, 160回, 477, 477, Aug. 2017
  (公社)日本獣医学会, Japanese
• 全エクソームシーケンスを用いたミニチュア・ダックスフントの炎症性結直腸ポリープ感受性遺伝子の探索
  永田矩之; 大田寛; 横山望; 田村昌大; 笹岡一慶; LEELA‐ARPORN Rommaneeya; DERMLIM Angkhana; NISA Khoirun; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜, 日本獣医学会学術集会講演要旨集, 160回, 477, 477, Aug. 2017
  (公社)日本獣医学会, Japanese
• 犬虚血性脳血管障害における脳底動脈血流の経頭蓋超音波ドプラ法による評価
  笹岡一慶; 大田寛; 田村昌大; 永田矩之; LEELA‐ARPORN Rommaneeya; DERMLIM Angkhana; KHOIRUN Nisa; 森田智也; 佐々木東; 森下啓太郎; 滝口満喜, 日本獣医学会学術集会講演要旨集, 160回, 465, 465, Aug. 2017
  (公社)日本獣医学会, Japanese
• 慢性腸疾患の犬における十二指腸の定量的造影超音波法(Quantitative contrast-enhanced ultrasonography of duodenum in dogs with chronic enteropathy)
  Khoirun Nisa; 大田 寛; 横山 望; 田村 昌大; 永田 矩之; 笹岡 一慶; Dermlim Angkhana; Leela-Arporn Rommaneeya; 森田 智也; 大菅 辰幸; 佐々木 東; 森下 啓太郎; 滝口 満喜, 日本獣医学会学術集会講演要旨集, 160回, 477, 477, Aug. 2017
  (公社)日本獣医学会, English
• イエネコのin vivo長期曝露試験:デカブロモジフェニルエーテル(BDE209)は甲状腺機能亢進症を引き起こすのか?
  水川葉月; 野見山桂; 池中良徳; 池中良徳; 中山翔太; SAENGTIENCHAI Aksorn; SAINNOXOI Tsendayush; 横山望; 笹岡一慶; 市居修; KHIDKHAN Kraisiri; 高居名菜; 滝口満喜; 田辺信介; 石塚真由美, 環境化学討論会要旨集(CD-ROM), 26th, ROMBUNNO.2A‐03, 05 Jun. 2017
  Japanese
• ミニチュア・ダックスフンドの炎症性結直腸ポリープにおけるCOX‐2発現とToll‐like receptorとの関連性の解析
  長谷川純也; 大田寛; 横山望; 笹岡一慶; NISA Khoirun; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜, 日本獣医学会学術集会講演要旨集, 159回, 456, 456, Aug. 2016
  (公社)日本獣医学会, Japanese
• 猫伝染性腹膜炎ウイルスの関与が疑われた拡張型心筋症様疾患の猫2例
  吉田 智彦; 市川 直紀; 小池 仁彦; 笹岡 一慶; 町田 登; 田口 正行, 動物臨床医学会年次大会プロシーディング, 36回, 2, 33, 34, Nov. 2015
  動物臨床医学会, Japanese
• 三尖弁異形成と診断した幼猫の1例
  吉田 智彦; 市川 直紀; 小池 仁彦; 笹岡 一慶; 町田 登; 田口 正行, 動物臨床医学会年次大会プロシーディング, 35回, 2, 37, 38, Nov. 2014
  動物臨床医学会, Japanese
• 犬の乳腺腫瘍と卵巣子宮疾患の併発状況
  吉田 智彦; 市川 直紀; 小池 仁彦; 笹岡 一慶; 田口 正行, 動物臨床医学会年次大会プロシーディング, 34回, 2, 329, 330, Nov. 2013
  動物臨床医学会, Japanese
• 犬の精巣腫瘍63例における局所浸潤と疫学的検討
  笹岡 一慶; 市川 直紀; 小池 仁彦; 吉田 智彦; 田口 正行, 動物臨床医学会年次大会プロシーディング, 34回, 2, 331, 332, Nov. 2013
  動物臨床医学会, Japanese
• 犬の頭蓋内疾患診断における経頭蓋超音波ドプラ法の有用性の検討
  SASAOKA KAZUYOSHI; NAKAMURA KENSUKE; MORISHITA KEITARO; OSUGA TATSUYUKI; LIM SUE YEE; OTA HIROSHI; YAMASAKI MASAHIRO; TAKIGUCHI MITSUYOSHI, 獣医麻酔外科学雑誌, 43, Suppl.1, 270, 270, Jun. 2012
  (一社)日本獣医麻酔外科学会, Japanese

• 〔主要な業績〕画像とシェーマで学ぶ犬と猫の超音波 Vol.4 頭頸胸部
  久保明; 笹岡一慶; 佐々木東; 新坊弦也; 中村健介, 脳
  学窓社, Aug. 2025, 9784873627991, 32431100;32431104, [Joint work]

• 〔Major achievements〕Infection Control Measures and Practical Examples in an Animal Hospital
  Kazuyoshi Sasaoka
  The 37th General Meeting of Japanese Society for Clinical Microbiology, 14 Feb. 2026, Japanese Society for Clinical Microbiology, Japanese, Nominated symposium
  13 Feb. 2026 - 15 Feb. 2026, Chiba, Japan, [Invited], [Domestic Conference]
• 〔Major achievements〕Differential diagnosis and treatment of Neurological disorders presenting with seizures in dogs and cats
  Kazuyoshi Sasaoka
  The 46th Annual Meeting of Japanese Society of Clinical Veterinary Medicine, 19 Oct. 2025, Animal Clinical Research Founfation, Japanese, Nominated symposium
  18 Oct. 2025 - 19 Oct. 2025, osaka, Japan, [Invited], [Domestic Conference]
• 〔主要な業績〕Google Formによる自己評価を利用した伴侶動物獣医療実習（ポリクリ）での取組
  笹岡一慶
  第74回東北・北海道地区高等教育研究会, 11 Sep. 2025, 東北・北海道地区高等教育研究会, Japanese, Oral presentation
  11 Sep. 2025 - 12 Sep. 2025, 札幌, Japan, [Domestic Conference]
• 〔主要な業績〕獣医学奨励賞受賞講演：犬における経頭蓋超音波ドプラ法を用いた脳血流評価の臨床的有用性に関する研究
  笹岡一慶
  第168回日本獣医学会学術集会, 04 Sep. 2025, 日本獣医学会, Japanese, Invited oral presentation
  03 Sep. 2025 - 06 Sep. 2025, 宮崎, Japan, 32431100;32431104;13227273;13227274, [Invited], [Domestic Conference]
• 〔主要な業績〕犬における経頭蓋超音波による脳および脳血管の描出性の検討
  昇良樹; 笹岡一慶; 新坊弦也; 横山望; 中村健介; 滝口満喜
  第168回日本獣医学会学術集会, 03 Sep. 2025, 日本獣医学会, Japanese, Oral presentation
  03 Sep. 2025 - 06 Sep. 2025, 宮崎, Japan, [Domestic Conference]
• 犬の肝臓におけるSuperb Microvascular Imagingの検者間信頼性の検討
  本田英俊; 横山望; 澤村飛龍; 菅原(須田; 芽伊; 川元誠; 新坊弦也; 笹岡一慶; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  第168回日本獣医学会学術集会, 03 Sep. 2025, 日本獣医学会, Japanese, Oral presentation
  03 Sep. 2025 - 06 Sep. 2025, 宮崎, Japan, [Domestic Conference]
• LC/Q-TOF/MSを用いたメタボロミクスによる犬大細胞性消化器型リンパ腫の血清バイオマーカー探索
  澤村飛龍; 横山 望; 池中良徳; 山崎淳平; 菅原(須田)芽伊; 笹岡一慶; 森下啓太郎; 中村健介; 滝口満喜
  第168回日本獣医学会学術集会, 03 Sep. 2025, 日本獣医学会, Japanese, Oral presentation
  03 Sep. 2025 - 06 Sep. 2025, 宮崎, Japan, [Domestic Conference]
• 〔主要な業績〕耳科処置により医原性気脳を発症した犬の1例
  川上侑記; 笹岡一慶; 田村純; 大山紀彦; 新坊弦也; 山根由久; 横山望; 中村健介; 滝口満喜
  令和7年度日本小動物獣医学会（北海道）, 28 Aug. 2025, 北海道獣医師会, Japanese, Oral presentation
  28 Aug. 2025 - 29 Aug. 2025, 帯広, Japan, [Domestic Conference]
• 〔主要な業績〕若齢期からの慢性的な運動失調を呈し、拡散テンソル画像（DTI）を用いて脳白質の萎縮を定量的に評価した猫の一例
  中村伽奈; 笹岡一慶; 新坊弦也; 山根由久; 中村健介; 滝口満喜
  令和7年度日本小動物獣医学会（北海道）, 28 Aug. 2025, 北海道獣医師会, Japanese, Oral presentation
  28 Aug. 2025 - 29 Aug. 2025, 帯広, Japan, [Domestic Conference]
• 〔主要な業績〕行動異常を主訴としたフレンチブルドッグの大脳膠腫症の一例
  加藤史; 笹岡一慶; 新坊弦也; 越川藍; 木村享史; 滝口満喜
  令和7年度日本小動物獣医学会（北海道）, 28 Aug. 2025, 北海道獣医師会, Japanese, Oral presentation
  28 Aug. 2025 - 29 Aug. 2025, 帯広, Japan, [Domestic Conference]
• 〔主要な業績〕感染症対策プログラムの前後における薬剤耐性菌と手指衛生意識の変化：大学附属動物病院での7年間での解析
  笹岡一慶
  獣医臨床感染症研究会 論文紹介セミナー, 16 Jul. 2025, 獣医臨床感染症研究会, Japanese, Public discourse
  オンライン, Japan, [Invited]
• Superb Micro-vascular Imagingを使用した心疾患犬における腎臓の微小血流評価
  安田 理紗; 中村 健介; 佐々木 東; 横山 望; 笹岡 一慶; 菅原 芽伊; 川元 誠; 塩原 希; 川上 侑記; 佐藤 景; 滝口満喜
  第122回日本獣医循環器学会定例大会, 29 Jun. 2025, 日本獣医循環器学会, Japanese, Oral presentation
  28 Jun. 2025 - 29 Jun. 2025, 東京、新橋, Japan, [Domestic Conference]
• 一過性の前庭徴候Episodic Vestibular Syndromeを呈した犬の特徴と診断
  山口敬央; 笹岡一慶; 大田寛; 新坊弦也; 菅原芽伊; 横山望; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  獣医神経病学会2025, 28 Jun. 2025, 獣医神経病学会, Japanese, Poster presentation
  28 Jun. 2025 - 29 Jun. 2025, 東京, Japan, [Domestic Conference]
• 〔主要な業績〕脳死疑いの昏睡症例における経頭蓋超音波検査による脳血流評価
  笹岡一慶; 山口敬央; 菅原芽伊; 新坊弦也; 大山紀彦; 田村純; 滝口満喜
  獣医神経病学会2025, 28 Jun. 2025, 獣医神経病学会, Japanese, Oral presentation
  28 Jun. 2025 - 29 Jun. 2025, 東京, Japan, [Domestic Conference]
• Detection of Congestive Heart Failure by Left Atrial Booster Strain in Cats with Cardiomyopathy
  Kei Sato; Kensuke Nakamura; Sei Kawamoto; Mei Sugawara; Kazuyoshi Sasaoka; Nozomu Yokoyama; Noboru Sasaki; Keitaro Morishita; Mitsuyoshi Takiguchi
  ACVIM FORUM 2025, 19 Jun. 2025, American College of Veterinary Internal Medicine, English, Oral presentation
  19 Jun. 2025 - 21 Jun. 2025, Louisville, Kentucky, United States, [International presentation]
• 〔主要な業績〕片側性大脳皮質形成異常症（脳室周囲異所性灰白質、多小脳回）の てんかん犬の一例
  郭 乃瑜; 笹岡 一慶; 福山 容一; 新坊 弦也; 菅原 芽伊; 横山 望; 佐々木 東; 森下 啓太郎; 中村 健介; 滝口 満喜
  日本獣医内科学アカデミー, 15 Feb. 2025, 日本獣医内科学アカデミー, Japanese, Oral presentation
  14 Feb. 2025 - 16 Feb. 2025, 東京, Japan, [Domestic Conference]
• 〔主要な業績〕動画で学ぶ神経疾患：レアな神経疾患
  笹岡一慶
  第21回日本獣医内科学アカデミー, 15 Feb. 2025, 日本獣医内科学アカデミー, Japanese, Public discourse
  14 Feb. 2025 - 16 Feb. 2025, 東京, Japan, [Invited], [Domestic Conference]
• 〔主要な業績〕てんかん重積の対応：2023ACVIMコンセンサス解説
  笹岡一慶
  第21回日本獣医内科学アカデミー学術大会, 15 Feb. 2025, 日本獣医内科学アカデミー, Japanese, Public discourse
  14 Feb. 2025 - 16 Feb. 2025, 東京, Japan, [Invited], [Domestic Conference]
• ラブラドール・レトリーバーのコロニーで集団発生したサルファ剤過敏症とCYPB5Rの遺伝子型頻度解析
  岸原果子; 横山望; 山崎淳平; 笹岡一慶; 森下啓太郎; 中村健介; 宮原和郎; 近藤厚; 滝口満喜; 高橋徹
  第42回日本獣医師会獣医学術学会年次大会, 24 Jan. 2025, 日本獣医師会, Japanese, Oral presentation
  24 Jan. 2025 - 26 Jan. 2025, 仙台, Japan, [Invited], [Domestic Conference]
• 〔主要な業績〕意識障害は起源不明髄膜脳脊髄炎（MUO）の予後不良に関連する： MUO82例の回顧的検討（2014～2022）
  笹岡一慶; 福家知樹; 須永隆文; 大田寛; 滝口満喜
  第42回日本獣医師会獣医学術学会年次大会, 24 Jan. 2025, 日本獣医師会, Japanese, Oral presentation
  24 Jan. 2025 - 26 Jan. 2025, 仙台, [Invited], [Domestic Conference]
• 〔主要な業績〕髄膜脳瘤と難治性てんかんの犬に対し内科療法と外科療法を併用し発作コントロールを得た一例
  山口敬央; 細谷謙次; 笹岡一慶; 大山紀彦; 田村 純; 新坊弦也; 大脇 綾; 竹内恭介; 木之下怜平; 金 尚昊; 奥村正裕
  2024年度第109回日本獣医麻酔外科学会学術集会, 21 Dec. 2024, 日本獣医麻酔外科学会, Japanese, Oral presentation
  20 Dec. 2024 - 20 Dec. 2024, 札幌市, Japan, [Domestic Conference]
• 猫の心筋症における左房ブースターストレインの有用性の検討
  佐藤景; 中村健介; 川元誠; 菅原芽伊; 笹岡一慶; 横山望; 佐々木東; 森下啓太郎; 滝口満喜
  第121回日本獣医循環器学会定例大会, 14 Dec. 2024, 日本獣医循環器学会, Japanese, Oral presentation
  14 Dec. 2024 - 15 Dec. 2024, 大阪, Japan, [Domestic Conference]
• ラブラドール・レトリーバーのコロニーで集団発生したサルファ剤過敏症とCYPB5Rの遺伝子型頻度解析
  岸原果子; 横山望; 山崎淳平; 笹岡一慶; 森下啓太郎; 中村健介; 宮原和郎; 近藤厚; 滝口満喜; 高橋徹
  令和6年度 日本小動物獣医学会（北海道）, 29 Aug. 2024, 北海道獣医師会, Japanese, Oral presentation
  29 Aug. 2024 - 30 Aug. 2024, 札幌市, [Domestic Conference]
• 意識障害は起源不明髄膜脳脊髄炎（MUO）の予後不良に関連する： MUO82例の回顧的検討（2014～2022）
  笹岡一慶; 福家知樹; 須永隆文; 大田寛; 滝口満喜
  令和6年度 日本小動物獣医学会（北海道）, 29 Aug. 2024, 北海道獣医師会, Japanese, Oral presentation
  29 Aug. 2024 - 30 Aug. 2024, 札幌, [Domestic Conference]
• 〔Major achievements〕Treatment Response, Course of Improvement, and Follow-up Information with Molnupiravir Treatment for Feline Infectious Peritonitis
  Shino Yoshida; Mei Sugawara; Kazuyoshi Sasaoka; Noboru Sasaki; Nozomu Yokoyama; Kensuke Nakamura; Keitaro Morishita; Sangho Kim; Takafumi Sunaga; Mitsuyoshi Takiguchi
  ACVIM FORUM 2024, 06 Jun. 2024, American College of Veterinary Internal Medicine, English, Oral presentation
  Minneapolis, United States, [International presentation]
• 〔主要な業績〕Prognostic factors for definitive-intent radiation therapy for the treatment of canine presumed intracranial meningiomas: A Retrospective Study of 90 cases
  Y. Fukuyama; K. Hosoya; S. Kim; T. Deguchi; S. Kanazono; G. Shimbo; K. Sasaoka; R. Kinoshita; K. Morishita; M. Takiguchi
  World Veterinary Cancer Congress Tokyo 2024, 23 Mar. 2024, English, Oral presentation
• 〔Major achievements〕Changes in MRI Findings During Molnupiravir Treatment in a Case of Neurotropic Feline Infectious Peritonitis
  片山 蒼; 笹岡一慶; 新坊弦也; 紀田 泉; 中村隼人; 前川直也; 松野啓太; 菅原芽伊; 横山 望; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  JCVIM2024, 23 Feb. 2024, JCVIM, Japanese, Oral presentation
  24 Feb. 2024 - 25 Feb. 2024, Tokyo, Japan, [Domestic Conference]
• 犬の発作性ジスキネジア23例の回顧的検討
  川上侑記; 笹岡一慶; 大田寛; 山根由久; 新坊弦也; 横山 望; 佐々木東; 森下啓太; 中村健介; 滝口満喜
  第20回日本獣医内科学アカデミー, 23 Feb. 2024, 日本獣医内科学アカデミー, Japanese, Oral presentation
  24 Feb. 2024 - 25 Feb. 2024, 東京, Japan, [Domestic Conference]
• 〔Major achievements〕Clinical Features and Diagnosis of Episodic Vestibular Signs in 30 Dogs (2016-2023)
  山口敬央; 笹岡一慶; 大田寛; 新坊弦也; 菅原芽伊; 横山望; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  JCVIM2024, 23 Feb. 2024, JCVIM, Japanese, Oral presentation
  24 Feb. 2024 - 25 Feb. 2024, Tokyo, Japan, [Domestic Conference]
• Ultrasonographic Findings in 43 Dogs Diagnosed with Chronic Cholecystitis
  越田凜太郎; 横山望; 賀川由美子; 菅原芽伊; 笹岡一慶; 新坊弦也; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  JCVIM2024, 23 Feb. 2024, JCVIM, Japanese, Oral presentation
  24 Feb. 2024 - 25 Feb. 2024, Tokyo, Japan, [Domestic Conference]
• A Case of Non-Effusive Feline Infectious Peritonitis in a Cat Exhibiting Neurological Symptoms During Treatment and Achieving Remission with Molnupiravir Dose Escalation
  前田和花; 森下啓太郎; 笹岡一慶; 菅原芽伊; 横山望; 佐々木東; 中村健介; 滝口満喜
  JCVIM2024, 24 Feb. 2024, JCVIM, Japanese, Oral presentation
  23 Feb. 2024 - 25 Feb. 2024, Tokyo, Japan, [Domestic Conference]
• A Case of Feline Infectious Peritonitis Achieving Remission through Colonic Granuloma Resection and Molnupiravir
  澤村飛龍; 横山望; 尚昊; 菅原芽伊; 笹岡一慶; 新坊弦也; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  JCVIM 2024, 24 Feb. 2024, JCVIM, Japanese, Oral presentation
  23 Feb. 2024 - 25 Feb. 2024, Tokyo, Japan, [Domestic Conference]
• 〔Major achievements〕Think from the chief complaint, Sudden falling
  中村健介; 中村篤史; 高野裕史; 笹岡一慶; 森田智也
  JCVIM 2024, 24 Feb. 2024, JCVIM, Japanese, Nominated symposium
  23 Feb. 2024 - 25 Feb. 2024, Tokyo, Japan, [Invited], [Domestic Conference]
• 〔Major achievements〕Canine and feline encephalitis
  Kazuyoshi Sasaoka
  JCVIM 2024, 25 Feb. 2024, JCVIM, Japanese, Public discourse
  23 Jan. 2024 - 25 Feb. 2024, Tokyo, Japan, [Invited], [Domestic Conference]
• 〔Major achievements〕Magnetic Resonance Imaging Scoring System for Prognostic Prediction in Presumed Canine Intracranial Gliomas Treated With Radiation Therapy
  Yohichi Fukuyama; Kenji Hosoya; Sangho Kim; Tatsuya Deguchi; Shinichi Kanazono; Genya Shimbo; Kazuyoshi Sasaoka; Ryohei Kinoshita; Keitaro Morishita; Mitsuyoshi Takiguchi
  2023 Veterinary Cancer Society Conference, Oct. 2023, Veterinary Cancer Society, English, Oral presentation
  12 Oct. 2023 - 14 Oct. 2023, Reno, Nevada, United States, [International presentation]
• 〔主要な業績〕標準的感染症対策プログラムは動物病院において手指衛生コンプライアンス向上と多剤耐性菌出現抑制に貢献する
  笹岡一慶; 森下啓太郎; 細谷謙次; 佐藤敬近; 佐藤豊孝; 堀内基広; 滝口満喜
  第166回日本獣医学会学術集会, Sep. 2023, 日本獣医学会, Japanese, Oral presentation
  05 Sep. 2023 - 18 Sep. 2023, [Domestic Conference]
• 〔主要な業績〕犬の発作性ジスキネジア23例の回顧的検討
  川上侑記; 笹岡一慶; 大田寛; 山根由久; 新坊弦也; 横山望; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  令和5年度日本小動物獣医学会（北海道）, 31 Aug. 2023, 北海道獣医師会, Japanese, Oral presentation
  江別, [Domestic Conference]
• 〔主要な業績〕神経超音波Neurosonologyの獣医学領域における可能性
  笹岡 一慶
  獣医神経病学会2023, 24 Jun. 2023, Japanese, Invited oral presentation
  24 Jun. 2023 - 25 Jun. 2023, 32431100;32431104, [Invited]
• 〔主要な業績〕頭部MRI検査のT2＊強調画像低信号病変が石灰化転移病変と診断された犬の1例
  宮城沙妃; 笹岡一慶; 新坊弦也; 青島圭佑; 横山望; 永田矩之; 森下啓太郎; 佐々木東; 中村健介; 滝口満喜
  第19回日本獣医内科学アカデミー学術大会, 26 Feb. 2023, 日本獣医内科学アカデミー, Japanese, Oral presentation
  17 Feb. 2023 - 21 Mar. 2023, 東京
• 慢性消化器症状を主訴に2次診療施設に来院したエキノコックス症の犬の1例
  紀田泉; 横山望; 林直樹; 中尾亮; 野中成晃; 笹岡一慶; 永田矩之; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  第19回日本獣医内科学アカデミー学術大会, 26 Feb. 2023, 日本獣医内科学アカデミー, Japanese, Oral presentation
  17 Feb. 2023 - 21 Mar. 2023, 東京
• 〔主要な業績〕経頭蓋ドプラ超音波検査の臨床応用
  笹岡一慶
  第19回獣医内科学アカデミー学術大会, 26 Feb. 2023, 日本獣医内科学アカデミー, Japanese, Invited oral presentation
  17 Feb. 2023 - 21 Mar. 2023, 東京, 32431100, [Invited]
• 〔主要な業績〕ケーススタディ：食べない犬その2
  笹岡一慶
  第19回獣医内科学アカデミー学術大会, 26 Feb. 2023, 日本獣医内科学アカデミー, Japanese, Invited oral presentation
  17 Feb. 2023 - 21 Mar. 2023, 東京, Japan, [Invited]
• 2次診療動物病院に来院した犬の糞便真核生物叢解析
  横山 望; 川口 剛; 中尾 亮; 森下 啓太郎; 細谷 謙次; 永田 矩之; 笹岡 一慶; 新坊 弦也; 佐々木; 中村 健介; 滝口 満喜
  第165回日本獣医学会学術集会, 22 Sep. 2022, 日本獣医学会, Japanese, Oral presentation
  06 Sep. 2022 - 08 Sep. 2022, 神奈川, Japan
• 〔主要な業績〕院内湿潤環境に対する注意喚起 北大附属動物病院における環境サーベイランス結果
  笹岡 一慶; 新田 優里香; 佐藤 豊孝; 堀内 基広; 滝口 満喜
  令和4年度小動物獣医学会（北海道）, 01 Sep. 2022, 北海道獣医師会, Japanese
  01 Sep. 2022 - 01 Sep. 2022
• 低コレステロール血症は犬の膵外分泌不全を予測できるのか?
  横山 望; 大田 寛; 永田 矩之; 笹岡 一慶; 新坊 弦也; 佐々木 東; 森下 啓太郎; 中村 健介; 滝口 満喜
  令和4年度小動物獣医学会（北海道）, 01 Sep. 2022, 北海道獣医師会, Japanese, Oral presentation
  01 Sep. 2022 - 01 Sep. 2022
• 〔主要な業績〕磁気共鳴スペクトロスコピーは犬の起源不明髄膜脳脊髄炎の予後指標となり得るか
  山口 敬央; 笹岡 一慶; 新坊 弦也; 山根 由久; 永田 矩之; 横山 望; 森下 啓太郎; 佐々木 東; 中村 健介; 滝口 満喜
  令和4年度小動物獣医学会（北海道）, 01 Sep. 2022, 北海道獣医師会, Japanese, Oral presentation
  01 Sep. 2022 - 01 Sep. 2022
• 犬尿中コルチゾール/クレアチニン比の基準値の確立とクッシング症候群の診断への応用
  永田 矩之; 澤村 飛龍; 五日市 大介; 森下 啓太郎; 細谷 謙次; 横山 望; 笹岡 一慶; 佐々木 東; 中村 健介; 池中 良徳; 滝口 満喜
  令和4年度小動物獣医学会（北海道）, 01 Sep. 2022, 北海道獣医師会, Japanese, Oral presentation
  01 Sep. 2022 - 01 Sep. 2022
• 〔主要な業績〕洞停止を認めた咳嗽失神の犬の1例
  幸野 瑠美; 中村 健介; 笹岡 一慶; 塩原 希; 小幡 祐路; 滝口 満喜
  北海道獣医師会雑誌, 01 Sep. 2022, 北海道獣医師会, Japanese, Oral presentation
  01 Sep. 2022 - 01 Sep. 2022
• 体内動態および行動毒性試験から見た動物用医薬品フィプロニルの影響評価
  鈴木智裕; 池中良徳; 中山翔太; 水川葉月; 一瀬貴大; 佐々木東; 笹岡一慶; 石塚真由美
  第162回日本獣医学会学術集会, Sep. 2019, Japanese, Oral presentation
  [Domestic Conference]
• 猫の新規炎症マーカー,ロイシンリッチα2糖蛋白質(LRG)の測定系構築の試み
  坂本暁彦; 大田寛; 好井健太朗; 矢吹悠久美; 笹岡一慶; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜
  第162回日本獣医学会学術集会, Sep. 2019, Japanese, Oral presentation
  [Domestic Conference]
• LC‐MS/MSを用いたイヌ尿中メタネフリンおよびノルメタネフリン測定
  井上裕美子; 佐々木東; 池中良徳; 一瀬貴大; 笹岡一慶; 大菅辰幸; 中山翔太; 森下啓太郎; 大田寛; 石塚真由美; 滝口満喜
  第162回日本獣医学会学術集会, Sep. 2019, Japanese, Oral presentation
  [Domestic Conference]
• 犬の僧帽弁疾患における2D Speckle Tracking心エコー図法を用いた左心房stiffnessの推定
  黒田杏子; 大菅辰幸; 笹岡一慶; 森下啓太郎; 佐々木東; 大田寛; 滝口満喜
  第162回日本獣医学会学術集会, Sep. 2019, Japanese
• 〔Major achievements〕北大附属動物病院における薬剤耐性モニタリング調査結果2018
  笹岡一慶; 森下啓太郎; 細谷謙次; 滝口満喜
  令和元年小動物獣医学会（北海道）, 29 Aug. 2019, Japanese, Oral presentation
  [Domestic Conference]
• 詳細な病理学的解析に基づいて治療方針を決定した免疫複合体性糸球体腎炎の犬の1例
  新井田篤; 大田寛; 笹岡一慶; 細谷謙次; 市居修; 賀川由美子; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜
  令和元年小動物獣医学会（北海道）, 29 Aug. 2019, Japanese, Oral presentation
  [Domestic Conference]
• デカブロモジフェニルエーテル(BDE209)の長期曝露がイエネコへ及ぼす影響
  田中啓介; 野見山桂; 水川葉月; 水川葉月; 高口倖暉; 田上瑠美; 横山望; 市居修; 滝口満喜; 笹岡一慶; 中山翔太; 池中良徳; 石塚真由美; 国末達也; 田辺信介
  環境化学討論会要旨集(CD-ROM), 11 Jun. 2019, Japanese
• 〔Major achievements〕経頭蓋超音波ドプラ法による脳血流評価を行った脳梗塞の犬の1例：脳動脈のダイナミックな血流変化の検出.
  笹岡 一慶; 大田 寛; 石塚 友人; 大菅 辰幸; 森下 啓太郎; 佐々木 東; 滝口 満喜
  第15回日本獣医内科学アカデミー学術大会, 16 Feb. 2019, Japanese, Oral presentation
  横浜, [Domestic Conference]
• 〔Major achievements〕一般診療エリアにおける院内感染対策：手術部位感染（SSI）対策を極める！〜院内感染症対策と外科医にできる工夫〜
  笹岡 一慶
  日本獣医麻酔外科学会北海道地区講習会, 06 Feb. 2019, Japanese, Public discourse
  [Invited], [Domestic Conference]
• 〔Major achievements〕経頭蓋超音波ドプラ法により局所的な脳循環動態を評価し得た右中大脳動脈梗塞の犬の1例
  笹岡一慶; 大田寛; 石塚友人; 大菅辰幸; 立花由莉加; 森下啓太郎; 佐々木東; 滝口満喜
  平成30年度小動物獣医学会（北海道）, 27 Sep. 2018, Japanese, Oral presentation
  札幌, [Domestic Conference]
• 神経症状を主訴とした悪性中皮腫の猫の1例
  大村侑己; 大田寛; 小林篤史; 笹岡一慶; 道下明日香; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜
  平成30年度小動物獣医学会（北海道）, 26 Sep. 2018, Japanese, Oral presentation
  札幌, [Domestic Conference]
• 神経筋接合部検査としてアイスパックテストを試みた重症筋無力症の犬の1例
  山田有紗; 笹岡一慶; 大田寛; 立花由莉加; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜
  平成30年度小動物獣医学会（北海道）, 26 Sep. 2018, Japanese, Oral presentation
  札幌, [Domestic Conference]
• Coming back to the graduate school.
  Kazuyoshi SASAOKA
  The 6th Sapporo Summer Seminar for One Health (Sapporo), 20 Sep. 2018, English, Nominated symposium
  Sapporo, [International presentation]
• Effect of cardiac volume loading on left atrial longitudinal strain analysis derived from two-dimensional Speckle Tracking Echocardiography in healthy dogs.
  Angkhana Dermlim; 中村 健介; 森田 智也; 大菅 辰幸; Khoirun Nisa; Rommaneeya Leela-arporn; 笹岡 一慶; 永田 矩之; 田村 昌大; 佐々木 東; 大田 寛; 森下 啓太郎; 滝口 満喜
  第161回日本獣医学会学術集会, Sep. 2018, English, Oral presentation
  筑波, [Domestic Conference]
• コンベンショナルな超音波診断装置による頭蓋内病変検出の試み
  佐々木東; 笹岡一慶; 大田寛; 大菅辰幸; 森下啓太郎; 滝口満喜
  日本超音波医学会平成28年度第1回超音波分子診断治療研究会, Aug. 2018, Japanese, Oral presentation
  札幌, [Domestic Conference]
• Demographic Features, Characteristics and Risk Factors in a Retrospective Study of Hepatocellular Carcinoma in Dogs.
  Rommaneeya Leela-arporn; Hiroshi Ohta; Noriyuki Nagata; Kazuyoshi Sasaoka; Tatsuyuki Osuga; Keitaro Morishita; Noboru Sasaki; Kensuke Nakamura; Mitsuyoshi Takiguchi
  American College of Veterinary Internal Medicine Forum 2018, 16 Jun. 2018, English, Poster presentation
  Seattle, [International presentation]
• 〔Major achievements〕Trace Elemental Profiles of Serum and Cerebrospinal Fluid in Dogs with Idiopathic Epilepsy.
  Kazuyoshi Sasaoka; Hiroshi Ohta; Hazuki Mizukawa; Shouta Nakayama; Noboru Sasaki; Keitaro Morishita; Yoshinori Ikenaka; Mayumi Ishizuka; Mitsuyoshi Takiguchi
  American College of Veterinary Internal Medicine Forum 2018, 16 Jun. 2018, English, Poster presentation
  Seattle, [International presentation]
• 有機ハロゲン化合物曝露によるネコの生化学マーカーの変化および甲状腺機能に及ぼす影響評価
  水川葉月; KHIDKHAN Kraisiri; 高口倖暉; 横山望; 市居修; 滝口満喜; 笹岡一慶; 池中良徳; 池中良徳; 中山翔太; TSEND‐AYUSH Sainnoxoi; 野見山桂; 田辺信介; 石塚真由美
  第27回環境化学討論会, 23 May 2018, Japanese, Oral presentation
  那覇, [Domestic Conference]
• ネコのin vivo BDE209長期曝露試験による体内動態の解明および甲状腺ホルモンへの影響評価
  田中啓介; 野見山桂; 水川葉月; 高口倖暉; 田上瑠美; 横山望; 市居修; 滝口満喜; 笹岡一慶; 中山翔太; 池中良徳; 石塚真由美; 国末達也; 田辺信介
  第27回環境化学討論会, 23 May 2018, Japanese, Oral presentation
  那覇, [Domestic Conference]
• Risk factors for hepatocellular carcinoma in dogs: a retrospective case-control study.
  Rommaneeya Leela-arporn; Hiroshi Ohta; Noriyuki Nagata; Masahiro Tamura; Kazuyoshi Sasaoka; Angkhana Dermlim; Khoirun Nisa; Tomoya Morita; Tatsuyuki Osuga; Morishita Keitaro; Noboru Sasaki; Mitsuyoshi Takiguchi
  第14回日本獣医内科学アカデミー学術大会, 18 Feb. 2018, English, Oral presentation
  横浜, [Domestic Conference]
• アドレナリン持続点滴が心原性肺水腫の救急管理に有用であった犬の1例.
  小島 一輝; 石塚 友人; 笹岡 一慶; 大菅 辰幸; 中村 健介; 滝口 満喜
  第14回日本獣医内科学アカデミー学術大会, 18 Feb. 2018, Japanese, Oral presentation
  横浜, [Domestic Conference]
• 〔Major achievements〕犬の特発性てんかんにおける血中及び脳脊髄液中微量元素濃度の検討.
  笹岡 一慶; 大田 寛; 水川 葉月; 中山 翔太; 佐々木 東; 森下 啓太郎; 池中 良徳; 石塚 真由美; 滝口 満喜
  第14回日本獣医内科学アカデミー学術大会, 17 Feb. 2018, Japanese, Oral presentation
  横浜, [Domestic Conference]
• 〔Major achievements〕Relationship between transcranial Doppler ultrasound vascular resistance parameters and intracranial hypertension in clinical dogs.
  Kazuyoshi SASAOKA; Hiroshi OHTA; Noboru SASAKI; Mitsuyoshi TAKIGUCHI
  Asian Meeting of Animal Medicine Specialties 2017, 11 Nov. 2017, English, Poster presentation
  Taegu, [International presentation]
• 〔Major achievements〕Diagnosis of intracranial hypertension and seizure using ultrasound: from small animal medicine to human medicine
  Kazuyoshi SASAOKA
  博士課程教育リーディングフォーラム2017, 20 Oct. 2017, English, Poster presentation
  名古屋, [Domestic Conference]
• Effects of Organohalogen Compounds on Serum Biochemical Profiles in Cats.
  Kraisiri KHIDKHAN; Hazuki MIZUKAWA; Yoshimori IKENAKA; Shota M; M. NAKAYAMA; Kei NOMIYAMA; Nozomu YOKOYAMA; Kazuyoshi SASAOKA; Osamu ICHII; Mitsuyoshi TAKIGUCHI; Shinsuke TANABE; Mayumi ISHIZUKA
  The 5th Sapporo Summer Seminar for One Health, 20 Sep. 2017, English, Poster presentation
  Sapporo, [International presentation]
• Elevation of transcranial Doppler ultrasound vascular resistance parameters are associated with intracranial hypertension in dogs with brain diseases.
  Kazuyoshi SASAOKA; Hiroshi OHTA; Noboru SASAKI; Mitsuyoshi TAKIGUCHI
  The 5th Sapporo Summer Seminar for One Health, 20 Sep. 2017, English, Poster presentation
  Sapporo, [International presentation]
• Quantitative contrast-enhanced ultrasonography of duodenum in dogs with chronic enteropathy.
  Khoirun Nisa; 大田 寛; 横山 望; 田村 昌大; 永田 矩之; 笹岡 一慶; Angkhana Dermlim; Rommaneeya Leela-Arporn; 森田 智也; 大菅 辰幸; 佐々木 東; 森下 啓太郎; 滝口 満喜
  第160回日本獣医学会学術集会, 14 Sep. 2017, English, Oral presentation
  鹿児島, [Domestic Conference]
• 〔Major achievements〕犬虚血性脳血管障害における脳底動脈血流の経頭蓋超音波ドプラ法による評価
  笹岡一慶; 大田寛; 田村昌大; 永田矩之; LEELA‐ARPORN Rommaneeya; DERMLIM Angkhana; KHOIRUN Nisa; 森田智也; 佐々木東; 森下啓太郎; 滝口満喜
  第160回日本獣医学会学術集会, 14 Sep. 2017, Japanese, Oral presentation
  鹿児島, [Domestic Conference]
• 犬慢性腸症の十二指腸粘膜におけるロイシンリッチα2糖蛋白の発現とその臨床的意義
  奥朋哉; 大田寛; 田村昌大; 永田矩之; 笹岡一慶; LEELA‐ARPORN Rommaneeya; DERMLIM Angkhana; NISA Khoirun; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜
  第160回日本獣医学会学術集会, 14 Sep. 2017, Japanese, Oral presentation
  鹿児島, [Domestic Conference]
• 全エクソームシーケンスを用いたミニチュア・ダックスフントの炎症性結直腸ポリープ感受性遺伝子の探索
  永田矩之; 大田寛; 横山望; 田村昌大; 笹岡一慶; LEELA‐ARPORN Rommaneeya; DERMLIM Angkhana; NISA Khoirun; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 滝口満喜
  第160回日本獣医学会学術集会, 14 Sep. 2017, Japanese, Oral presentation
  鹿児島, [Domestic Conference]
• イエネコのin vivo長期曝露試験:デカブロモジフェニルエーテル(BDE209)は甲状腺機能亢進症を引き起こすのか?
  水川葉月; 野見山桂; 池中良徳; 池中良徳; 中山翔太; SAENGTIENCHAI Aksorn; SAINNOXOI Tsendayush; 横山望; 笹岡一慶; 市居修; KHIDKHAN Kraisiri; 高居名菜; 滝口満喜; 田辺信介; 石塚真由美
  第26回環境化学討論会, 05 Jun. 2017, Japanese, Oral presentation
  静岡, [Domestic Conference]
• 〔Major achievements〕犬における大脳白質病変の臨床的意義に関する検討： 高齢犬の側脳室周囲高信号は症状に関連するか?
  笹岡 一慶; 大田 寛; 華園 究; 佐々木 東; 森下 啓太郎; 中村 健介; 滝口 満喜
  第13回日本獣医内科学アカデミー学術大会, 18 Feb. 2017, Japanese, Oral presentation
  横浜, [Domestic Conference]
• 〔Major achievements〕経頭蓋超音波ドプラ法を用いた犬の非侵襲的脳圧亢進診断.
  笹岡 一慶; 大田 寛; 佐々木 東; 滝口 満喜
  北海道大学第3回部局横断シンポジウム, 26 Jan. 2017, English, Poster presentation
  札幌, [Domestic Conference]
• ミニチュア・ダックスフンドの炎症性結直腸ポリープにおけるCOX‐2発現とToll‐like receptorとの関連性の解析
  長谷川純也; 大田寛; 横山望; 笹岡一慶; NISA Khoirun; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
  第159回日本獣医学会学術集会, 30 Aug. 2016, Japanese, Oral presentation
  藤沢, [Domestic Conference]
• 猫伝染性腹膜炎ウイルスの関与が疑われた拡張型心筋症様疾患の猫2例
  吉田智彦; 市川直紀; 小池仁彦; 笹岡一慶; 町田登; 田口正行
  第36回動物臨床医学会, 20 Nov. 2015, Japanese, Oral presentation
  大阪, [Domestic Conference]
• 三尖弁異形成と診断した幼猫の1例
  吉田智彦; 市川直紀; 小池仁彦; 笹岡一慶; 町田登; 田口正行
  第35回動物臨床医学会, 14 Nov. 2014, Japanese, Oral presentation
  大阪, [Domestic Conference]
• 消化管にクリプトコッカス病変が認められた猫の１例.
  田口 正行; 市川 直紀; 小池 仁彦; 吉田 智彦; 笹岡 一慶
  第23回中部小動物臨床研究発表会, 05 Oct. 2014, Japanese, Oral presentation
  名古屋, [Domestic Conference]
• 犬の乳腺腫瘍と卵巣子宮疾患の併発状況
  吉田智彦; 市川直紀; 小池仁彦; 笹岡一慶; 田口正行
  第34回動物臨床医学会, 15 Nov. 2013, Japanese, Oral presentation
  大阪, [Domestic Conference]
• 〔Major achievements〕犬の精巣腫瘍63例における局所浸潤と疫学的検討
  笹岡一慶; 市川直紀; 小池仁彦; 吉田智彦; 田口正行
  第34回動物臨床医学会, 15 Nov. 2013, Japanese, Oral presentation
  大阪, [Domestic Conference]
• 〔Major achievements〕経頭蓋超音波ドプラ法の臨床的有用性に関する研究.
  笹岡 一慶; 中村 健介; 森下 啓太郎; 大菅 辰幸; Lim Sue Yee; 横山 望; 大田 寛; 山_ 真大; 滝口 満喜
  第9回日本獣医内科学アカデミー学術大会, 23 Feb. 2013, Japanese, Oral presentation
  横浜, [Domestic Conference]
• 〔Major achievements〕犬の頭蓋内疾患診断における経頭蓋超音波ドプラ法の有用性の検討
  笹岡一慶; 中村健介; 森下啓太郎; 大菅辰幸; LIM Sue Yee; 大田寛; 山崎真大; 滝口満喜
  第51回日本獣医画像診断学会, 01 Jun. 2012, Japanese, Oral presentation
  大宮, [Domestic Conference]

• 伴侶動物獣医療実習, 2024年, 学士課程, 獣医学部
• 総合専門臨床特論, 2024年, 博士後期課程, 獣医学院
• プレクリニカル実習, 2024年, 学士課程, 獣医学部
• 伴侶動物獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部
• 伴侶動物獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部
• 伴侶動物獣医療実習Ⅱ, 2024年, 学士課程, 獣医学部
• 伴侶動物獣医療実習Ⅱ, 2024年, 学士課程, 獣医学部
• 夜間・救急獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部
• 夜間・救急獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部
• 総合獣医療実習, 2024年, 学士課程, 獣医学部
• 総合獣医療実習, 2024年, 学士課程, 獣医学部
• アドバンスト演習, 2024年, 学士課程, 獣医学部
• アドバンスト演習, 2024年, 学士課程, 獣医学部
• アドバンスト演習, 2024年, 学士課程, 獣医学部
• 内科学各論, 2024年, 学士課程, 獣医学部
• プレクリニカル実習, 2024年, 学士課程, 獣医学部
• アドバンスト演習, 2024年, 学士課程, 獣医学部
• 内科学総論, 2024年, 学士課程, 獣医学部

• 2025 - Present
  日本臨床微生物学会
• 2025 - Present
  獣医臨床感染症研究会
• Present
  Japan Veterinary Medical Association
• Present
  The Japanese Society of Veterinary Science
• Present
  Japanese Society of Veterinary Neurology

• 北大獣医内科学教室Webページ
  Kazusyohi Sasaoka, Aug. 2018 - Present, [Web service]
• BM Counter (iOS)
  App Store, Kazusyohi Sasaoka, Feb. 2018 - Present, [Software]
• WBC Counter
  App Store, Kazusyohi Sasaoka, Feb. 2018 - Present, [Software]
• Bone marrow cells counter
  Google Play, Kazusyohi Sasaoka, Jan. 2018 - Present, [Software]
• WBC counter
  Google Play, Kazusyohi Sasaoka, Jan. 2018 - Present, [Software]

• ワンヘルスアプローチによるモンゴルにおける食中毒起因菌と薬剤耐性菌の調査研究
  科学研究費助成事業
  Sep. 2024 - Mar. 2028
  堀内 基広; 佐藤 豊孝; 笹岡 一慶
  日本学術振興会, 国際共同研究加速基金(海外連携研究), 北海道大学, ［Internationally co-authored］, 24KK0134
• 犬における臨床応用可能な脳血管反応性検査法の確立
  科学研究費助成事業 基盤研究(C)
  01 Apr. 2021 - 31 Mar. 2024
  笹岡 一慶
  本研究は脳循環の予備能力を示す脳血管反応性を対象とし、モダリティと負荷条件の検証により、超音波検査を用いた臨床応用可能な非侵襲的脳血管反応性検査法をイヌにおいて確立することを目的とした研究である。ヒトでは脳血管反応性は血管障害性疾患である脳梗塞のリスク因子に留まらず、認知機能不全や代謝性脳疾患など様々の脳疾患で低下することが明らかとなっており、脳疾患の根底に存在する脳血管反応性について注目が集まっている。しかしながら、犬や猫を実験動物として利用した基礎研究が過去に行われたものの、獣医臨床で利用できる侵襲性の低い脳血管反応性検査法は検討されておらず、いずれの疾患犬においても脳血管反応性は明らかにされていない。研究の初年度である本年は脳血管反応性検査法の条件検討に着手する計画であったが、新型コロナウイルス感染症の影響により実験健常犬の確保に当初の想定を大幅に超えて時間がかかっている。一方で、高磁場MRIと経頭蓋超音波ドプラ法による脳血流測定モダリティでは、臨床症例において安定した測定を実施できている。また、本期間中に実験計画の再検討を行い、超音波検査による脳血管反応性検査の再現性の検証を最初期に実施する計画に再編し、さらに統計的な実験計画の検討により必要頭数を再試算して削減することが可能となる統計的結果を得た。これらにより次年度初期からの検討開始が可能な状況を整備することが可能となった。本研究により、獣医臨床で利用できる検査法を確立するということは、実験動物としての犬だけではなく、自然発症の疾患犬を対象にできるということである。人と動物が同じ疾患を持ちながらも、異なる特性を持つことに着目する概念は、汎動物学として近年着目を浴びており、互いの疾患に対する病態解明や発症要因、新たな治療法に迫る手がかりとなり得る。
  日本学術振興会, 基盤研究(C), 北海道大学, 21K05913
• Evaluation of cerebral blood flow using transcranial Doppler ultrasound: establishment of the index to detect seizure activity
  Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows
  25 Apr. 2018 - 31 Mar. 2020
  笹岡 一慶
  獣医療において、重度なけいれん発作の治療モニタリングはほとんど行われてこなかった。脳波検査に基づく電気活動的な“Seizure Free”が治療の目標であるが、獣医療において現状利用可能な肉眼的観察では“Seizure Free”が達成されているかは分からない。本研究では近年獣医療で急速に普及している超音波診断装置を利用し、経頭蓋超音波ドプラ法による脳血流評価を用いたけいれん発作の新規治療モニタリング法を検討することとした。本研究では①実験的けいれん発作モデルにおける脳血流波形変化の解析、②集中治療中のけいれん発作症例犬における経時的な脳血流波形解析、のアプローチを計画した。
  2018年度は実験的けいれん発作モデル犬における脳血流波形変化の解析を目標とし、実験的にけいれん発作モデルを作出し、発作によって生じる脳血流波形の変化を経頭蓋超音波ドプラ法を用いて解析した。全身麻酔下の正常実験犬にペンテトラゾール持続点滴により実験的けいれん発作モデル犬を作出した。本モデルにおける発作時には脳底動脈平均血流速度の120-160%上昇、中大脳動脈平均血流速度の120-220%上昇を認め、経頭蓋超音波ドプラ法において脳血流速度上昇が発作の指標となることが示唆された。また、脳血管抵抗指標は脳底動脈で低下傾向を認め、発作時において脳血管拡張が生じていることを経頭蓋超音波ドプラ法が捉えているものと考えられた。今後、血流波形の更なる解析や他の生理的パラメータとの組み合わせにより、さらに鋭敏に発作時の血流変化を捉える指標を検討し、臨床症例において蓄積されたデータを検討する予定である。また、同手法の研究を通じて、犬の脳梗塞症例における経時的な脳血流変化を獣医学領域で初めて捉えることに成功した。学会報告および国際誌への投稿を予定している。
  今後も経頭蓋超音波ドプラ法の適応拡大を目標に研究を実施する。
  Japan Society for the Promotion of Science, Grant-in-Aid for JSPS Fellows, Hokkaido University, 18J11947
• 経頭蓋超音波ドプラ法による犬の脳血流評価：発作モニタリングへの応用の検討
  平成29年度リーディングプログラム大学院学生科学研究費
  Aug. 2017 - Mar. 2018
  笹岡一慶
  北海道大学博士課程教育リーディングプログラム「One Healthに貢献する獣医科学グローバルリーダー育成プログラム」, Principal investigator, Competitive research funding
• 犬の特発性てんかんにおける血中および脳脊髄液中微量元素濃度の検討
  クリニカルニュートリション研究会2016年度スカラーシッププログラム
  Jun. 2016 - Oct. 2017
  笹岡一慶
  クリニカルニュートリション研究会, Principal investigator, Competitive research funding
• 経頭蓋超音波ドプラ法による犬の脳血流評価の臨床的有用性に関する研究
  平成28年度リーディングプログラム大学院学生科学研究費
  Aug. 2016 - Mar. 2017
  笹岡一慶
  北海道大学博士課程教育リーディングプログラム「One Healthに貢献する獣医科学グローバルリーダー育成プログラム」, Principal investigator, Competitive research funding

• peer review
  Peer review
  Peer review etc
  Canadian Veterinary Journal, Frontiers in Neurology, Japanese Journal of Veterinary Research, Journal of Veterinary Emergency and Critical Care, Open Veterinary Journal, The Journal of Veterinary Medical Science, Veterinary Record Case Reports

• 〔Major achievements〕Medical Record Writing and Clinical Reasoning
  06 Aug. 2025
  Lecturer
  Hokkaido University Veterinary Teaching Hospital
  HUVTH Postgraduate Education Seminar
  General
• 〔Major achievements〕Infection Control Measures in Veterinary Hospitals: Initiatives at the Hokkaido University Veterinary Teaching Hospital
  20 Nov. 2024
  Lecturer
  Animal Products Safety Division, Ministry of Agriculture, Forestry and Fisherie
  Mini-Seminar on Antimicrobial Resistance (AMR) Countermeasures in the Veterinary Field
• 〔Major achievements〕Menigoencephalitis update 2024
  15 May 2024
  Lecturer
  Hokkaido University Veterinary Teaching Hospital
  HUVTH Postgraduate Education Seminar
  College students, Graduate students, Researchers, General
• 〔Major achievements〕Early explaination of ACVIM status epilepticus consensus 2023
  06 Dec. 2023
  Lecturer
  Hokkaido University Veterinary Teaching Hospital
  HUVTH Postgraduate Education Seminar
• 〔Major achievements〕Diagnosis of Epilepsy and Antiepileptic Drug Therapy: A Review from the Basics
  29 Oct. 2023
  Lecturer
  The Hokkaido Veterinary Medical Association
  Iburi Branch Small Animal Seminar
  General
• 〔Major achievements〕Basic lecture program: Brain diseases 3
  04 Sep. 2023 - 01 Oct. 2023
  Lecturer
  Japanese Society of Veterinary Neurology
  Basic lecture program
• 〔Major achievements〕Basic lecture program: Brain diseases 2
  04 Sep. 2023 - 01 Oct. 2023
  Lecturer
  Japanese Society of Veterinary Neurology
  Basic lecture program
• 〔Major achievements〕Basic lecture program: Brain diseases 1
  04 Sep. 2023 - 01 Oct. 2023
  Lecturer
  Japanese Society of Veterinary Neurology
  Basic lecture program
• 〔Major achievements〕Treatment to Status epilepticus; a dog in neuro ICU
  06 Jun. 2018
  Lecturer
  Hokkaido University Veterinary Teaching Hospital
  HUVTH卒後教育セミナー
  札幌

• Introduction of Hokkaido University Veterinary Teaching Hospital
  May 2024
  共立製薬
  Small Animal Clinic NAVI
  [Internet]

• Jan. 2026 - Present
  infection control doctor
• Sep. 2024 - Sep. 2024
  国際協力機構（JICA）短期派遣専門家
  ザンビア大学獣医学部臨床教育強化プロジェクトにおいて、獣医神経内科学を指導した。