NAM Jin-Minresearchmap個人ページ

Last Updated : 2018/05/03

Basic Information

Profile

Affiliation
Global Institute for Collaborative Research and Education Global Station for Quantum Medical Science and Engineering
Job TitleLecturer 
Degree
E-mail
URL
Research funding number

Research Keywords

Cell movement, Cell adhesion

Research Areas

Clinical internal medicine / Radiation science
Biological science / Structural biochemistry
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Clinical internal medicine / Radiation science
Biological science / Structural biochemistry

Career

2008/02
-
2010/05
Lawrence Berkeley National Laboratory
2007/09
-
2008/01
Japan Society for the promotion of Science
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2008/02
-
2010/05
Lawrence Berkeley National Laboratory
2007/09
-
2008/01
Japan Society for the promotion of Science

Academic Background

-
2002
Kyoto University Department of Synthetic Chemistry and Biological Chemistry
-
1999
Sogang University Chemistry
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-
2002
Kyoto University Department of Synthetic Chemistry and Biological Chemistry
-
1999
Sogang University Chemistry

Academic Societies

THE JAPANESE CANCER ASSOCIATION
The Molecular Biology Society of Japan.
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THE JAPANESE CANCER ASSOCIATION
The Molecular Biology Society of Japan.

Research Activities

Papers

Toll-like receptor 3 signal augments radiation-induced tumor growth retardation in a murine model.
Yoshida S, Shime H, Takeda Y, Nam JM, Takashima K, Matsumoto M, Shirato H, Kasahara M, Seya T.
Cancer Sci 2018
Targeting integrins with RGD-conjugated gold nanoparticles in radiotherapy decreases the invasive activity of breast cancer cells.
Wu PH, Onodera Y, Ichikawa Y, Rankin EB, Giaccia AJ, Watanabe Y, Qian W, Hashimoto T, Shirato H, Nam JM*.
Int J Nanomedicine. 14(12) 5069-5085 2017/07
Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes.
Kon S, Ishibashi K, Katoh H, Kitamoto S, Shirai T, Tanaka S, Kajita M, Ishikawa S, Yamauchi H, Yako Y, Kamasaki T, Matsumoto T, Watanabe H, Egami R, Sasaki A, Nishikawa A, Kameda I, Maruyama T, Narumi R, Morita T, Sasaki Y, Enoki R, Honma S, Imamura H, Oshima M, Soga T, Miyazaki JI, Duchen MR, Nam JM, Onodera Y, Yoshioka S, Kikuta J, Ishii M, Imajo M, Nishida E, Fujioka Y, Ohba Y, Sato T, Fujita Y
Nature cell biology 19(5) 530-541 2017/05
Nik-related kinase regulates trophoblast proliferation and placental development by modulating AKT phosphorylation.
Morioka Y, Nam JM, Ohashi T
PloS one 12(2) e0171503 2017
High expression of EPB41L5, an integral component of the Arf6-driven mesenchymal program, correlates with poor prognosis of squamous cell carcinoma of the tongue.
Otsuka Y, Sato H, Oikawa T, Onodera Y, Nam JM, Hashimoto A, Fukunaga K, Hatanaka KC, Hatanaka Y, Matsuno Y, Fukuda S, Sabe H
Cell communication and signaling : CCS 14(1) 1-9 2016/11
Hypoxia: Signaling the Metastatic Cascade.
Rankin EB, Nam JM, Giaccia AJ.
2(6) 295-304 2016/06
Evaluation of the relative biological effectiveness of spot-scanning proton irradiation in vitro.
Maeda K, Yasui H, Matsuura T, Yamamori T, Suzuki M, Nagane M, Nam JM, Inanami O, Shirato H
Journal of radiation research 57(3) 311 2016/06
P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.
Hashimoto A, Oikawa T, Hashimoto S, Sugino H, Yoshikawa A, Otsuka Y, Handa H, Onodera Y, Nam JM, Oneyama C, Okada M, Fukuda M, Sabe H
The Journal of cell biology 213(1) 81-95 2016/04
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways.
Onodera Y, Nam JM, Bissell MJ
The Journal of clinical investigation 124(1) 367-384 2014/01
Intracellular trafficking of integrins in cancer cells.
Onodera Y, Nam JM, Sabe H
Pharmacology & therapeutics 140(1) 1-9 2013/10
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Toll-like receptor 3 signal augments radiation-induced tumor growth retardation in a murine model.
Yoshida S, Shime H, Takeda Y, Nam JM, Takashima K, Matsumoto M, Shirato H, Kasahara M, Seya T.
Cancer Sci 2018
Targeting integrins with RGD-conjugated gold nanoparticles in radiotherapy decreases the invasive activity of breast cancer cells.
Wu PH, Onodera Y, Ichikawa Y, Rankin EB, Giaccia AJ, Watanabe Y, Qian W, Hashimoto T, Shirato H, Nam JM*.
Int J Nanomedicine. 14(12) 5069-5085 2017/07
Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes.
Kon S, Ishibashi K, Katoh H, Kitamoto S, Shirai T, Tanaka S, Kajita M, Ishikawa S, Yamauchi H, Yako Y, Kamasaki T, Matsumoto T, Watanabe H, Egami R, Sasaki A, Nishikawa A, Kameda I, Maruyama T, Narumi R, Morita T, Sasaki Y, Enoki R, Honma S, Imamura H, Oshima M, Soga T, Miyazaki JI, Duchen MR, Nam JM, Onodera Y, Yoshioka S, Kikuta J, Ishii M, Imajo M, Nishida E, Fujioka Y, Ohba Y, Sato T, Fujita Y
Nature cell biology 19(5) 530-541 2017/05
Nik-related kinase regulates trophoblast proliferation and placental development by modulating AKT phosphorylation.
Morioka Y, Nam JM, Ohashi T
PloS one 12(2) e0171503 2017
High expression of EPB41L5, an integral component of the Arf6-driven mesenchymal program, correlates with poor prognosis of squamous cell carcinoma of the tongue.
Otsuka Y, Sato H, Oikawa T, Onodera Y, Nam JM, Hashimoto A, Fukunaga K, Hatanaka KC, Hatanaka Y, Matsuno Y, Fukuda S, Sabe H
Cell communication and signaling : CCS 14(1) 1-9 2016/11
Hypoxia: Signaling the Metastatic Cascade.
Rankin EB, Nam JM, Giaccia AJ.
2(6) 295-304 2016/06
Evaluation of the relative biological effectiveness of spot-scanning proton irradiation in vitro.
Maeda K, Yasui H, Matsuura T, Yamamori T, Suzuki M, Nagane M, Nam JM, Inanami O, Shirato H
Journal of radiation research 57(3) 311 2016/06
P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.
Hashimoto A, Oikawa T, Hashimoto S, Sugino H, Yoshikawa A, Otsuka Y, Handa H, Onodera Y, Nam JM, Oneyama C, Okada M, Fukuda M, Sabe H
The Journal of cell biology 213(1) 81-95 2016/04
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways.
Onodera Y, Nam JM, Bissell MJ
The Journal of clinical investigation 124(1) 367-384 2014/01
Intracellular trafficking of integrins in cancer cells.
Onodera Y, Nam JM, Sabe H
Pharmacology & therapeutics 140(1) 1-9 2013/10
Co-overexpression of GEP100 and AMAP1 proteins correlates with rapid local recurrence after breast conservative therapy.
Kinoshita R, Nam JM, Ito YM, Hatanaka KC, Hashimoto A, Handa H, Otsuka Y, Hashimoto S, Onodera Y, Hosoda M, Onodera S, Shimizu S, Tanaka S, Shirato H, Tanino M, Sabe H
PloS one 8(10) 2013
β1-Integrin via NF-κB signaling is essential for acquisition of invasiveness in a model of radiation treated in situ breast cancer.
Nam JM, Ahmed KM, Costes S, Zhang H, Onodera Y, Olshen AB, Hatanaka KC, Kinoshita R, Ishikawa M, Sabe H, Shirato H, Park CC
Breast cancer research : BCR 15(4) 2013
Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.
Onodera Y, Nam JM, Hashimoto A, Norman JC, Shirato H, Hashimoto S, Sabe H
The Journal of cell biology 197(7) 983-996 2012/06
Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin.
Nam JM, Onodera Y, Bissell MJ, Park CC
Cancer research 70(13) 5238-5248 2010/07
beta1 integrin targeting to enhance radiation therapy.
Nam JM, Chung Y, Hsu HC, Park CC
International journal of radiation biology 85(11) 923-928 2009/11
The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.
Sabe H, Hashimoto S, Morishige M, Ogawa E, Hashimoto A, Nam JM, Miura K, Yano H, Onodera Y
Traffic (Copenhagen, Denmark) 10(8) 982-993 2009/08
EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts.
Miura K, Nam JM, Kojima C, Mochizuki N, Sabe H
Molecular biology of the cell 20(7) 1949-1959 2009/04
[Breast neoplasms: invasion and metastasis].
Onodera Y, Nam JM
Nihon rinsho. Japanese journal of clinical medicine 65 Suppl 6 33-38 2007/06
CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.
Nam JM, Onodera Y, Mazaki Y, Miyoshi H, Hashimoto S, Sabe H
The EMBO journal 26(3) 647-656 2007/02
Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2.
Mazaki Y, Hashimoto S, Tsujimura T, Morishige M, Hashimoto A, Aritake K, Yamada A, Nam JM, Kiyonari H, Nakao K, Sabe H
Nature immunology 7(7) 724-731 2006/07
Construction of engineered yeast with the ability of binding to cellulose
Nam JM, Fujita Y, Arai T, Kondo A, Morikawa Y, Okada H, Ueda M, Tanaka A
J Mol Cat B: Enzymatic 17(3-5) 197-202 2002

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