Researcher Profile and Settings

Master

Affiliation (Master)

• Faculty of Medicine　Surgery　Surgery

Affiliation (Master)

• Faculty of Medicine　Surgery　Surgery

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Profile and Settings

Profile and Settings

• Name (Japanese)

  Kato

• Name (Kana)

  Nobuyasu

• Name

  201901007868497262

Achievement

Research Areas

• Life sciences / Cardiovascular surgery

Published Papers

• Reconstruction of right ventricular outflow tract with severe calcification: lantern procedure.

  Takahiro Ishigaki, Satoru Wakasa, Koji Sato, Nobuyasu Kato, Yasuhiro Kamikubo

  General thoracic and cardiovascular surgery 2023/08/24 

  Right ventricular outflow tract reconstruction is repeatedly required after the Rastelli procedure. However, standard right ventricular outflow tract reconstruction using direct anastomosis on the posterior right ventricular outflow tract wall is unfeasible in cases with severe calcification. Herein, we present a novel technique called the "lantern procedure," which can fix the prosthetic pulmonary valve without anastomosis to the calcified right ventricular outflow tract wall.
• A Noonan-like pediatric patient with a de novo CBL pathogenic variant and an RNF213 polymorphism p.R4810K presenting with cardiopulmonary arrest due to left main coronary artery ostial atresia.

  Ayako Chida-Nagai, Hidefumi Tonoki, Naomasa Makita, Hiroyuki Ishiyama, Masafumi Ihara, Yuji Maruo, Takao Tsujioka, Daisuke Sasaki, Gaku Izumi, Hirokuni Yamazawa, Nobuyasu Kato, Masaki Ito, Miki Fujimura, Osamu Sasaki, Atsuhito Takeda

  American journal of medical genetics. Part A 2023/08/09 

  Left main coronary artery ostial atresia (LMCAOA) is an extremely rare condition. Here, we report the case of a 14-year-old boy with Noonan syndrome-like disorder in whom LMCAOA was detected following cardiopulmonary arrest. The patient had been diagnosed with Noonan syndrome-like disorder with a pathogenic splice site variant of CBL c.1228-2 A > G. He suddenly collapsed when he was running. After administering two electric shocks using an automated external defibrillator, the patient's heartbeat resumed. Cardiac catheterization confirmed the diagnosis of LMCAOA. Left main coronary artery angioplasty was performed. The patient was discharged without neurological sequelae. Brain magnetic resonance imaging revealed asymptomatic Moyamoya disease. In addition, RNF213 c.14429 G > A p.R4810K was identified. There are no reports on congenital coronary malformations of compound variations of RNF213 and CBL. In contrast, the RNF213 p.R4810K polymorphism has been established as a risk factor for angina pectoris and myocardial infarction in adults, and several congenital coronary malformations due to genetic abnormalities within the RAS/MAPK signaling pathway have been reported. This report aims to highlight the risk of sudden death in patients with RASopathy and RNF213 p.R4810K polymorphism and emphasize the significance of actively searching for coronary artery morphological abnormalities in these patients.
• 左冠動脈口閉鎖症による心肺停止を呈した、RNF213 p.R4810K多型とCBL病的バリアントの両方を有する小児例

  永井 礼子, 佐々木 理, 丸尾 優爾, 辻岡 孝郎, 佐々木 大輔, 泉 岳, 山澤 弘州, 加藤 伸康, 武田 充人

  日本小児循環器学会総会・学術集会抄録集 (NPO)日本小児循環器学会 59回 [I - 02] 2023/07
• 当科における冠動脈に対する外科介入

  加藤 伸康, 阿部 慎司, 新宮 康栄, 大岡 智学, 加藤 裕貴, 山澤 弘州, 武田 充人, 若狭 哲

  日本小児循環器学会総会・学術集会抄録集 (NPO)日本小児循環器学会 59回 [II - 03] 2023/07
• Staged definitive repair for pulmonary atresia and ventricular septal defect 40 years after palliative surgery: a case report

  Noriyoshi Ebuoka, Norihiro Ando, Hidetsugu Asai, Nobuyasu Kato, Tsuyoshi Tachibana, Satoru Wakasa

  General Thoracic and Cardiovascular Surgery Cases 2023/06/05
• 大動脈縮窄・離断症に対する大動脈弓形成手術後気道出血発症のリスク因子

  泉 岳, 斉藤 仁志, 加藤 裕貴, 水野谷 和之, 糸洲 佑介, 西川 直樹, 武田 充人, 山澤 弘州, 加藤 伸康, 森本 裕二

  日本集中治療医学会雑誌 (一社)日本集中治療医学会 30 (Suppl.1) S648 - S648 1340-7988 2023/06
• 大動脈縮窄・離断症に対する大動脈弓形成手術後気道出血発症のリスク因子

  泉 岳, 斉藤 仁志, 加藤 裕貴, 水野谷 和之, 糸洲 佑介, 西川 直樹, 武田 充人, 山澤 弘州, 加藤 伸康, 森本 裕二

  日本集中治療医学会雑誌 (一社)日本集中治療医学会 30 (Suppl.1) S648 - S648 1340-7988 2023/06
• Usefulness of Prolonged PR Interval to Predict Atrial Tachyarrhythmia Development Following Surgical Repair of Tetralogy of Fallot.

  Gaku Izumi, Atsuhito Takeda, Hirokuni Yamazawa, Ayako Nagai, Daisuke Sasaki, Itsumi Sato, Nobuyasu Kato, Tsuyoshi Tachibana

  The American journal of cardiology 184 127 - 132 2022/09/17 

  Atrial tachyarrhythmias (ATAs), which may occur after tetralogy of Fallot (TOF) surgery, can cause sudden cardiac death. However, ATAs may also develop in response to electrical substrates. This study aims to examine the predictive factors for ATAs by identifying electrical substrates in the atrium obtained from 12-lead electrocardiogram in patients who underwent TOF repair. A total of 144 patients aged >15 years (median, 31.6 years) who underwent TOF repair at Hokkaido University were enrolled. We investigated the correlation between the development of ATAs with age, time interval after initial corrective surgery, brain natriuretic peptide levels, cardiac magnetic resonance parameters (right ventricular end-diastolic volume index, right ventricular end-systolic volume index, right ventricular ejection fraction, right atrial volume index, left ventricular end-diastolic volume index, left ventricular ejection fraction), and 12-lead electrocardiogram parameters (P wave maximum voltage, PR interval, QRS width, number of fragmented QRS). Of the 144 patients, 44 patients (30.6%) developed ATAs. Multivariate analysis revealed time interval after initial corrective surgery (odds ratio 6.7, 95% confidence interval 1.78 to 12.6) and PR interval (odds ratio 2.7, 95% confidence interval: 1.17 to 4.20) as independent risk factors for the development of ATAs. The receiver operating characteristic curve revealed a PR interval cut-off value of >200 milliseconds as predictive of the development of ATAs in patients more than 15 years after initial corrective surgery (area under the curve, 0.658; sensitivity, 71.4%; specificity, 66.4%). The present study demonstrated that a prolonged PR interval is a simple and convenient predictor for the development of ATAs in patients who underwent TOF repair.
• Changes in Cerebral Hemodynamics During Systemic Pulmonary Shunt and Pulmonary Artery Banding in Infants with Congenital Heart Disease.

  Yoshifumi Takeda, Masataka Yamamoto, Koji Hoshino, Yoichi M Ito, Nobuyasu Kato, Satoru Wakasa, Yuji Morimoto

  Pediatric cardiology 2022/09/01 

  Palliative surgery is often performed in the treatment of congenital heart disease. Two representative palliative procedures are the systemic pulmonary shunt and pulmonary artery banding. Dramatic changes in cerebral hemodynamics may occur in these operations due to changes in the pulmonary-to-systemic blood flow ratio and systemic oxygenation. However, there seem to be almost no studies evaluating them. Accordingly, we evaluated cerebral perfusion by transcranial Doppler ultrasonography and cerebral oxygenation by near infrared spectroscopy during these procedures. In the post hoc analysis of a previous prospective observational study, cerebral blood flow velocities of the middle cerebral artery measured by transcranial Doppler were compared between the start and end of surgery as were the pulsatility index and resistance index. The cerebral oxygenation values were also compared between the start and end of surgery. Twenty-two infants with systemic pulmonary shunt and 20 infants with pulmonary artery banding were evaluated. There were no significant differences of the flow velocities between the start and end of surgery in either procedure. The pulsatility index significantly increased after pulmonary artery banding, which may compete with the increase in cerebral perfusion due to the increase in systemic blood flow. The cerebral oxygenation decreased in both procedures, possibly due to an increase in body temperature. Arterial oxygen saturation was almost the same before and after both procedures. Contrary to our expectation, the changes in cerebral hemodynamics in the palliative operations were small if the management of physiological indices such as arterial oxygen saturation was properly performed during the procedures.
• 当院の体肺動脈短絡手術の治療成績

  加藤 伸康, 阿部 慎司, 新宮 康栄, 加藤 裕貴, 大岡 智学, 泉 岳, 山澤 弘州, 武田 充人, 若狭 哲

  日本小児循環器学会総会・学術集会抄録集 (NPO)日本小児循環器学会 58回 [III - 04] 2022/07
• 胎児診断を行ったCantrell症候群の臨床経験

  佐々木 大輔, 辻岡 孝郎, 永井 礼子, 泉 岳, 山澤 弘州, 武田 充人, 稗田 哲也, 加藤 伸康, 佐々木 理

  日本小児循環器学会総会・学術集会抄録集 (NPO)日本小児循環器学会 58回 [I - 03] 2022/07
• 植込型補助人工心臓治療におけるunmet medical needsの考察

  渡部 克将, 大岡 智学, 松本 嶺, 東 亮太, 須野 賢一郎, 稗田 哲也, 石垣 隆弘, 村瀬 亮太, 阿部 慎司, 加藤 伸康, 加藤 裕貴, 新宮 康栄, 若狭 哲

  北海道外科雑誌 北海道外科学会 67 (1) 92 - 92 0288-7509 2022/06
• Bronchial artery hypertrophy-associated perioperative pulmonary hemorrhage in cardiovascular surgery: a case report.

  Shinji Abe, Yasuhiro Kamikubo, Nobuyasu Kato, Hiroki Kato, Tomonori Ooka, Yasushige Shingu, Satoru Wakasa

  Surgical case reports 8 (1) 80 - 80 2022/04/29 

  BACKGROUND: Pulmonary hemorrhage is a life-threatening complication of cardiovascular surgery. Bronchial artery hypertrophy, a rare pathology associated with inflammatory and ischemic respiratory diseases, increases the risk of pulmonary hemorrhage; however, its involvement in cardiovascular surgery is not well known. We present two cardiovascular surgical cases in which embolization of the hypertrophied bronchial artery was effective in controlling perioperative pulmonary hemorrhage. CASE PRESENTATION: The first case was a 51-year-old man with chronic obstructive pulmonary disease who developed acute type A aortic dissection. After emergent surgery, his blood pressure suddenly dropped in the intensive care unit; computed tomography revealed a right hemothorax. Because a 4-mm dilated bronchial artery was identified on preoperative computed tomography, the hemothorax was suspected to be associated with bronchial artery hypertrophy. Selective bronchial arteriography was emergently performed and revealed a right pulmonary parenchymal blush. After subsequent coil embolization of the bronchial artery, the parenchymal blush disappeared, and his hemodynamic condition stabilized. The second case was a 66-year-old man with bronchiectasis who was referred for redo aortic valve replacement due to structural valve deterioration. A bioprosthesis was previously implanted to avoid permanent anticoagulation because the patient had repeated episodes of hemoptysis; however, he still had persistent hemosputum during admission for the redo aortic valve replacement. A dilated bronchial artery 3.7 mm in size was incidentally identified on preoperative computed tomography, and hence, the repeated hemosputum was suspected to be associated with bronchial artery hypertrophy. Bronchial arteriography revealed a right pulmonary parenchymal blush, and prophylactic embolization of the bronchial artery was performed. The hemosputum disappeared after the procedure, and redo aortic valve replacement was performed uneventfully 8 days later. CONCLUSION: In cardiovascular surgery, the risk of pulmonary hemorrhage associated with bronchial artery hypertrophy should be considered, especially in patients with inflammatory and ischemic respiratory diseases.
• Perioperative junctional ectopic tachycardia associated with congenital heart disease: risk factors and appropriate interventions.

  Gaku Izumi, Atsuhito Takeda, Hirokuni Yamazawa, Nobuyasu Kato, Hiroki Kato, Tsuyoshi Tachibana, Osamu Sagae, Ryogo Yahagi, Motoki Maeno, Koji Hoshino, Hitoshi Saito

  Heart and vessels 37 (10) 1792 - 1800 2022/04/25 

  The risk factors and the appropriate interventions for perioperative junctional ectopic tachycardia (JET) in congenital heart disease (CHD) surgery have not been sufficiently investigated despite the severity of this complication. This study aimed to examine the risk factors and interventions for perioperative JET. From 2013 to 2020, 1062 surgeries for CHD (median patient age: 4.3 years, range 0.0-53.0) with or without a cardiopulmonary bypass (CPB) were performed at Hokkaido University, Japan. We investigated the correlation between perioperative JET morbidity factors, such as age, genetic background, CPB/aortic cross-clamp (ACC) time, use of inotropes and dexmedetomidine, STAT score, and laboratory indices. The efficacy of JET therapies was also evaluated. Of the 1062 patients, 86 (8.1%) developed JET. The 30-day mortality was significantly high in JET groups (7% vs. 0.8%). The independent risk factors for JET included heterotaxy syndrome [odds ratio (OR) 4.83; 95% confidence interval (CI) 2.18-10.07], ACC time exceeding 90 min (OR 1.90; CI 1.27-2.39), and the use of 3 or more inotropes (OR 4.11; CI 3.02-5.60). The combination of anti-arrhythmic drugs and a temporary pacemaker was the most effective therapy for intractable JET. Perioperative JET after CHD surgery remains a common cause of mortality. Inotrope use was a risk factor for developing JET overall surgery risk. In short ACC surgeries, heterotaxy syndrome could increase the risk of JET, which could develop even without inotrope use in long ACC surgeries. It is crucial not to delay the treatment in cases with unstable hemodynamics caused by this arrhythmia. It is recommended to reduce numbers not dose of inotropes.
• 人工知能を用いた心大血管手術後長期リハビリ症例予測モデルの構築と検証

  村瀬 亮太, 新宮 康栄, 加藤 伸康, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本臨床外科学会雑誌 日本臨床外科学会 83 (3) 600 - 600 1345-2843 2022/03
• 幼少期に留置した肺動脈ステント内狭窄に対する外科治療の経験

  加藤 伸康, 新宮 康栄, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本成人先天性心疾患学会雑誌 日本成人先天性心疾患学会 11 (1) 195 - 195 2022/01
• L-Carnitine supplementation for the prevention of postoperative atrial fibrillation in aortic valve surgery.

  Yasushige Shingu, Nobuyasu Katoh, Tomonori Ooka, Hiroki Katoh, Satoru Wakasa

  General thoracic and cardiovascular surgery 69 (11) 1460 - 1466 2021/11 

  OBJECTIVES: L-Carnitine, a quaternary amine, improves fatty acid metabolism in the heart and has anti-inflammatory effects. Several studies have reported the efficacy of L-carnitine for the prophylaxis of arrhythmia. We assessed the clinical effectiveness of L-carnitine in preventing postoperative atrial fibrillation (POAF) in aortic valve surgery. METHODS: Thirty patients who underwent aortic valve surgery were included. Fifteen patients had no prophylaxis other than conventional measures (control), while 15 patients received oral L-carnitine for 9 days (daily dose of 3 g). The incidence of POAF during 1 week after surgery was compared between the two groups. The multivariable logistic regression analysis for POAF was performed using the pre- and intraoperative parameters. RESULTS: Preoperative characteristics and operative data were comparable between the groups. The POAF rate was significantly lower in the L-carnitine group than in the control (20% and 60%, respectively; P = 0.025). L-Carnitine use was an independently negative predictor for POAF (odds ratio 0.067; 95% confidence interval 0.006-0.768). CONCLUSIONS: L-Carnitine administration may have potential for the prevention of POAF in aortic valve surgery.
• 低左心機能を伴う虚血性閉鎖不全症〜外科手術vs Mitraclip〜 虚血性僧帽弁閉鎖不全症に対する外科治療戦略

  若狭 哲, 新宮 康栄, 加藤 伸康, 阿部 慎司, 大岡 智学, 松居 喜郎

  日本胸部外科学会定期学術集会 (一社)日本胸部外科学会 74回 CWS2 - 3 2021/10
• 混合型TAPVC術後の遺残病変修復に際して垂直静脈を遊離グラフトとして用いた1例

  渡部 克将, 加藤 伸康, 庭野 陽樹, 松本 嶺, 東 亮太, 須野 賢一郎, 石垣 隆弘, 稗田 哲也, 村瀬 亮太, 阿部 慎司, 新宮 康栄, 大岡 智学, 若狭 哲

  日本胸部外科学会定期学術集会 (一社)日本胸部外科学会 74回 CCPA3 - 8 2021/10
• クロロキンの心筋虚血再灌流障害抑制効果の実験的検討

  村瀬 亮太, 新宮 康栄, 加藤 伸康, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本胸部外科学会定期学術集会 (一社)日本胸部外科学会 74回 COP35 - 4 2021/10
• ファロー四徴症に対するValve slicingを用いた肺動脈弁温存の検討

  稗田 哲也, 加藤 伸康, 新宮 康栄, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本胸部外科学会定期学術集会 (一社)日本胸部外科学会 74回 COD38 - 3 2021/10
• Intralobar pulmonary sequestration associated with left main coronary artery obstruction and mitral regurgitation.

  Yusuke Motohashi, Tatsuya Kato, Nobuyasu Kato, Masato Aragaki, Aki Fujiwara-Kuroda, Tsuyoshi Tachibana, Yasuhiro Hida, Kichizo Kaga, Satoru Wakasa

  General thoracic and cardiovascular surgery 69 (12) 1575 - 1579 2021/09/21 [Refereed]
   

  A 4-year-old boy with left intralobar pulmonary sequestration associated with left main coronary artery obstruction (LMCAO) and severe mitral regurgitation (MR) was admitted to our hospital. Since the patient presented with dyskinesia of the cardiac apex and increased left ventricular end-diastolic volume (LVEDV), left main coronary artery reconstruction and mitral annuloplasty were performed. The enlargement of the left ventricle was improved after sequential surgeries. There was a risk of deterioration of MR and regrowth of LVEDV due to shunt blood flow; therefore, left lower lobectomy and aberrant artery division were performed. This is a very rare case of a patient with pulmonary sequestration associated with LMCAO and severe MR.
• Left ventricular inflow obstruction due to a coronary arteriovenous fistula: a paediatric case report.

  Ayako Chida-Nagai, Hirokuni Yamazawa, Takao Tsujioka, Kota Taniguchi, Osamu Sasaki, Gaku Izumi, Nobuyasu Kato, Atsuhito Takeda

  BMC cardiovascular disorders 21 (1) 389 - 389 2021/08/11 [Refereed]
   

  BACKGROUND: We report a rare case of left ventricular inflow obstruction from a branch of the left circumflex coronary artery to the right atrium caused by a coronary arteriovenous fistula (CAVF) in a young Japanese male child. CASE PRESENTATION: The patient was diagnosed with CAVF following a heart murmur shortly after birth. The left-to-right shunt caused right ventricular volume overload and pulmonary congestion. An emergency surgical intervention was performed for the CAVF on day 6 after birth. However, by 5 years of age, his left ventricular inflow obstruction worsened. We found an abnormal blood vessel originating from the proximal part of a branch of the left circumflex coronary artery, circling the outside of the mitral valve annulus along the medial side of the coronary sinus. As the child gets older, the blood inflow into the left ventricle might get restricted further, resulting in left-sided heart failure. CONCLUSION: Our findings suggest that even after CAVF closure surgery, it is essential to monitor for complications caused by progressive dilatation of a persistent CAVF.
• Intra-Atrial Rerouting of Anomalous Systemic Venous Connection and Septation of Common Atrium in Intracardiac Repair of Complete Atrioventricular Septal Defect with Left Isomerism and Dextrocardia: A Case Report

  Kato Nobuyasu, Takeda Atsuhito, Arai Yosuke, Hatta Eiichiro, Yakuwa Satoshi, Shingu Yasushige, Ooka Tomonori, Wakasa Satoru

  Pediatric Cardiology and Cardiac Surgery 特定非営利活動法人 日本小児循環器学会 37 (2) 126 - 132 0911-1794 2021/08/01 [Not refereed]
   

  Left isomerism is frequently associated with anomalous systemic venous connection and common atrium, requiring systemic venous abnormality correction and common-atrium septation in biventricular repair. Our case was a 4-year-old girl diagnosed with left isomerism, dextrocardia, complete atrioventricular septal defect, common atrium, bilateral superior vena cava, and interruption of the inferior vena cava with hemiazygos vein connection. She underwent intracardiac repair with intra-atrial rerouting. Preoperative computed tomography suggested that extracardiac reconstruction of the anomalous systemic vein was inappropriate, and showed that all the pulmonary veins drain to the common chamber in the common atrium. Thus, the blood flow from the right superior vena cava was diverted into the left side of the common atrium through an intra-atrial tunnel. Complete atrioventricular septal defect was repaired with modified one-patch method, and the patch divided the common atrium into the right and left atria. She was discharged on postoperative day 11 without obstruction in systemic and pulmonary venous return. Therefore, if all the pulmonary veins drain to the common chamber, intra-atrial rerouting may effectively correct anomalous systemic venous connection in the septation of the common atrium.
• ファロー四徴症術後のPQ時間延長は頻脈性心房性不整脈発症の予測因子となる

  泉 岳, 武田 充人, 山澤 弘州, 永井 礼子, 佐々木 大輔, 佐藤 逸美, 加藤 伸康

  日本小児循環器学会総会・学術集会抄録集 (NPO)日本小児循環器学会 57回 [OR26 - 2] 2021/07
• ファロー四徴症術後のPQ時間延長は頻脈性心房性不整脈発症の予測因子となる

  泉 岳, 武田 充人, 山澤 弘州, 永井 礼子, 佐々木 大輔, 佐藤 逸美, 加藤 伸康

  日本小児循環器学会総会・学術集会抄録集 (NPO)日本小児循環器学会 57回 [OR26 - 2] 2021/07
• About a definition of the persistent fifth aortic arch.

  Nobuyasu Kato

  The Annals of thoracic surgery 2021/02/08
• 心室拡大による機能性僧帽弁閉鎖不全症の外科治療 左室リモデリングを中心に考える機能性僧帽弁閉鎖不全症に対する外科治療

  若狭 哲, 新宮 康栄, 石垣 隆弘, 加藤 伸康, 加藤 裕貴, 大岡 智学

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 51回 SY3 - 4 2021/02
• 小児房室弁(単心室共通房室弁を含む)形成術 右側房室弁にEbstein病様の異形成を合併した共通房室弁閉鎖不全に対する弁形成

  加藤 伸康, 新宮 康栄, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 51回 VS2 - 4 2021/02
• Arterial switch operation後の死亡・再介入関連因子の検討

  稗田 哲也, 加藤 伸康, 新宮 康栄, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 51回 OP28 - 1 2021/02
• Frozen elephant trunk術後早期SINE発生のリスク因子

  佐藤 公治, 加藤 伸康, 新宮 康栄, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 51回 OP32 - 4 2021/02
• Frozen elephant trunk術後dSINEリスクの検討

  佐藤 公治, 加藤 伸康, 新宮 康栄, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本血管外科学会雑誌 (NPO)日本血管外科学会 30 (Suppl.) O24 - 1 0918-6778 2021
• 止血デバイスを用いた経皮的腹部ステントグラフト内挿術の創合併症予防効果の検討

  鍋島 龍一, 石垣 隆弘, 加藤 伸康, 加藤 裕貴, 新宮 康栄, 大岡 智学, 若狭 哲

  日本血管外科学会雑誌 (NPO)日本血管外科学会 30 (Suppl.) O37 - 1 0918-6778 2021
• Total Anomalous Pulmonary Venous Connection with Lethal Pulmonary Venous Obstruction Managed by Multidisciplinary Cooperation.

  Kana Ito, Ayako Chida-Nagai, Osamu Sasaki, Nobuyasu Kato, Takeshi Umazume, Satoshi Kawaguchi, Kazutoshi Cho, Gaku Izumi, Hirokuni Yamazawa, Atsuhito Takeda

  Case reports in pediatrics 2021 6619458 - 6619458 2021 [Refereed]
   

  Background: Total anomalous pulmonary venous connection (TAPVC) is a critical congenital heart disease for which emergency surgery is required after birth. In cases of no intervention, TAPVC is associated with a high mortality rate in the first year of life. Although foetal echocardiographic techniques for diagnosing TAPVC have improved, TAPVC remains one of the most difficult congenital heart diseases to diagnose via foetal echocardiography. Here, we report a case of TAPVC with pulmonary venous obstruction (PVO), which was diagnosed via foetal echocardiography. Case Presentation. On foetal echocardiography at 32 weeks' gestation, a large atrial septal defect, enlarged superior vena cava, and continuous flow pattern in the vertical vein from the common chamber were observed in the foetus. Paediatric cardiologists and cardiac surgeons, neonatologists, and obstetricians planned to perform a caesarean section and emergency heart surgery. The male infant was born at 37 weeks' gestation via caesarean section, and postnatal echocardiography revealed PVO at the confluence of the superior vena cava and common chamber. Similarly, chest computed tomography confirmed the foetal diagnosis. The postnatal diagnoses were TAPVC type Ib, PVO, atrial septal defect, and patent ductus arteriosus. Surgical repair of the TAPVC was initiated within the first 3 hours of life. Screening brain echocardiography and head computed tomography revealed intracranial haemorrhage and hydrocephalus. Therefore, the patient underwent emergency bilateral external drainage on day 13. On day 48, a ventriculoperitoneal shunt was inserted owing to progressive brain ventricular dilatation. The patient was discharged home on postoperative day 68. Conclusions: Although the prognosis of TAPVC with PVO remains poor, continuous observation through foetal echocardiography and early interdepartmental collaboration can result in good outcomes.
• 先天性心疾患周術期接合部頻拍のリスク因子

  泉 岳, 武田 充人, 山澤 弘州, 永井 礼子, 阿部 二郎, 谷口 宏太, 加藤 伸康, 荒木 大

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 36 (Suppl.2) s2 - 212 0911-1794 2020/11
• 予防的DKS術後の大動脈弁逆流・旧肺動脈弁逆流に対する検討

  谷口 宏太, 永井 礼子, 阿部 次郎, 泉 岳, 山澤 弘州, 武田 充人, 加藤 伸康

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 36 (Suppl.2) s2 - 246 0911-1794 2020/11
• 二心室修復可能な心疾患に対する姑息的右室流出路再建術8例の検討

  加藤 伸康, 橘 剛, 新宮 康栄, 若狭 哲, 加藤 裕貴, 大岡 智学, 山澤 弘州, 武田 充人

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 36 (Suppl.2) s2 - 383 0911-1794 2020/11
• 胸腹部大動脈瘤手術時の肋間動脈再建法の工夫と脊髄保護 internal cuff reimplantation法の有用性

  佐藤 公治, 杉本 聡, 加藤 伸康, 新宮 康栄, 杉木 宏司, 加藤 裕貴, 大岡 智学, 若狭 哲

  日本胸部外科学会定期学術集会 (一社)日本胸部外科学会 73回 CTA1 - 5 2020/10
• 感染症対策を見据えたVAD治療の進歩と臨床展開 VAD関連感染症の治療戦略 大網と局所閉鎖陰圧療法の適用と有効性

  大岡 智学, 布施川 真哲, 鍋島 龍二, 小市 裕太, 稗田 哲也, 石垣 隆弘, 佐藤 公治, 加藤 伸康, 新宮 康栄, 若狭 哲

  人工臓器 (一社)日本人工臓器学会 49 (2) S - 53 0300-0818 2020/10
• Persistent Fifth Aortic Arch with Left Ventricular Dysfunction and Left Bronchial Obstruction.

  Nobuyasu Kato, Tsuyoshi Tachibana, Hidetsugu Asai, Noriyoshi Ebuoka, Yasushige Shingu, Tomonori Ooka, Hiroki Kato, Satoru Wakasa

  The Annals of thoracic surgery 110 (5) e361-e363  2020/04/18 [Refereed][Not invited]
   

  Persistent fifth aortic arch is a rare anomaly in congenital heart disease, which is often associated with aortic obstructive diseases. We report a 7-month-old infant diagnosed persistent fifth aortic arch (AA) with left ventricular dysfunction along with left bronchial malacia due to compression from own heart. Surgical repair was performed including AA reconstruction using the 5th-AA as an in-situ flap to enlarge the 4th-AA with end-to-end anastomosis, and external stenting for the left bronchial malacia. Postoperative courses were uneventful. On computed tomography, a reconstructed aortic arch without obstruction and an expanded left bronchus were seen.
• Type IIエンドリークに対する腰動脈結紮・ステントグラフト温存瘤縫縮術

  小市 裕太, 新宮 康栄, 新井 洋輔, 石垣 隆弘, 安東 悟央, 稗田 哲也, 佐藤 公治, 加藤 伸康, 関 達也, 加藤 裕貴, 若狭 哲, 大岡 智学

  日本インターベンショナルラジオロジー学会雑誌 (一社)日本インターベンショナルラジオロジー学会 34 (4) 298 - 298 1340-4520 2020/04
• Forns Index is a predictor of cardiopulmonary bypass time and outcomes in Fontan conversion.

  Gaku Izumi, Atsuhito Takeda, Hirokuni Yamazawa, Osamu Sasaki, Nobuyasu Kato, Hidetsugu Asai, Tsuyoshi Tachibana, Yoshiro Matsui

  Heart and vessels 35 (4) 586 - 592 2020/04 [Refereed][Not invited]
   

  Recent reports suggested that cardiopulmonary bypass (CPB) time is one of the risk factors for postoperative complications after Fontan conversion. Although Fontan conversion may be performed for the patients with hepatic fibrosis after initial Fontan procedure, there is no predictive indicator regarding the liver function associated with hemostasis which can affects CPB time. Thirty-one patients who underwent Fontan conversion using the same surgical procedure (extracardiac conduit conversion with right atrium exclusion) were enrolled. In multivariate analyses including age at Fontan conversion, interval from initial Fontan to conversion, hemodynamic data such as right atrial pressure, ventricular end-diastolic pressure, and cardiac index, hepatic data such as platelet count, prothrombin time international normalized ratios, serum total bilirubin, hyaluronic acid levels, five known indices for hepatic fibrosis (Forns Index, APRI, FIB4, FibroIndex, and MELD-XI), and liver stiffness measured by ultrasound elastography, only the Forns Index remained independently associated with the CPB time (P < 0.01) and blood transfusions (plasma transfusions and platelet concentrations: P < 0.01 for both). The cutoff level for Forns Index to predict the prolonged CPB time (exceeding 240 min) was 4.85 by receiver-operating characteristic curve (area under the curve 0.823, sensitivity 76.9%, and specificity 72.2%). Three patients with Forns Index > 7.0 had poor outcomes with long CPB time and massive blood transfusions in contrast with the other 28 patients. In conclusion, Forns Index could serve as a practical predictor of CPB time and is associated with blood transfusion volume in Fontan conversion.
• 心筋症に対する外科的左室負荷軽減と「アジュバント治療」の可能性

  新宮 康栄, 稗田 哲也, 加藤 伸康, 若狭 哲, 大岡 智学

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 50回 PR20 - 1 2020/03
• 機能性僧帽弁逆流に対する置換術式による左室内エネルギー損失の違い VFMによる検討

  石垣 隆弘, 新宮 康栄, 加藤 伸康, 若狭 哲, 大岡 智学, 大川 洋平, 山田 陽, 高橋 順一郎, 松居 喜郎

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 50回 O9 - 1 2020/03
• 肺動脈血栓内膜摘除は慢性血栓塞栓性肺高血圧症に対する標準治療であり続けられるか?

  大岡 智学, 小市 裕太, 稗田 哲也, 荒木 大, 石垣 隆弘, 安東 悟央, 佐藤 公治, 加藤 伸康, 新宮 康栄, 若狭 哲, 加藤 裕貴

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 50回 O11 - 4 2020/03
• 当院における完全型房室中隔欠損症に対する二心室修復の成績

  稗田 哲也, 加藤 伸康, 小市 裕太, 安東 悟央, 荒木 大, 石垣 隆弘, 佐藤 公治, 新宮 康栄, 若狭 哲, 加藤 裕貴, 大岡 智学, 橘 剛

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 50回 P2 - 3 2020/03
• Perioperative changes of the slope in the preload recruitable stroke work relationship by a single-beat technique after mitral valve surgery in functional mitral regurgitation with non-ischemic dilated cardiomyopathy.

  Takahiro Ishigaki, Yasushige Shingu, Nobuyasu Katoh, Satoru Wakasa, Hiroki Katoh, Tomonori Ooka, Suguru Kubota, Yoshiro Matsui

  General thoracic and cardiovascular surgery 68 (1) 30 - 37 2020/01 [Refereed][Not invited]
   

  OBJECTIVES: The slope in the preload recruitable stroke work relationship is a highly linear, load-insensitive contractile parameter. However, the perioperative change of the slope has not been reported before. We examined the perioperative slope from a steady-state single beat in patients with functional mitral regurgitation and assessed the correlation with brain natriuretic peptide (BNP) levels. METHODS: The study included 16 patients with non-ischemic dilated cardiomyopathy and refractory heart failure: 10 patients underwent mitral valve plasty and left ventricular plasty (MVP + LVP group) and 6 patients who underwent mitral valve replacement and papillary muscle tugging approximation (MVR + PMTA group). The left ventricular ejection fraction was assessed by the modified Simpson method; the slope was assessed by the single-beat technique using transthoracic echocardiography. BNP levels were measured by chemiluminescent immunoassay. RESULTS: The left ventricular ejection fraction and slope did not significantly change from pre- to early post-surgery in the MVP + LVP group. Both the left ventricular ejection fraction and slope significantly increased 6 months after surgery in the MVR + PMTA group. Postoperative BNP level was low in the MVR + PMTA group. While the postoperative left ventricular ejection fraction did not correlate with BNP levels, the postoperative slope significantly correlated with BNP level after surgery in the MVP + LVP group and in the total functional mitral regurgitation group. CONCLUSIONS: The change of slope was dependent on surgical procedures. In functional mitral regurgitation, the slope may be a more sensitive parameter in reflecting the left ventricular contractile function than the left ventricular ejection fraction.
• 肉眼的に乳頭状線維弾性腫と鑑別が困難であったvilloustype左房粘液腫の1例

  石垣 隆弘, 新宮 康栄, 加藤 伸康, 若狭 哲, 大岡 智学, 加藤 裕貴, 若林 健人, 三橋 智子, 松居 喜郎

  北海道外科雑誌 北海道外科学会 64 (2) 207 - 207 0288-7509 2019/12
• カルニチンによる心臓弁膜症手術後の心房細動の予防(単群介入試験)

  新宮 康栄, 小市 裕太, 稗田 哲也, 新井 洋輔, 安東 悟央, 石垣 隆弘, 佐藤 公治, 加藤 伸康, 若狭 哲, 大岡 智学

  北海道外科雑誌 北海道外科学会 64 (2) 209 - 209 0288-7509 2019/12
• 肉眼的に乳頭状線維弾性腫と鑑別が困難であったvillous type左房粘液腫の1例

  石垣 隆弘, 新宮 康栄, 加藤 伸康, 若狭 哲, 大岡 智学, 加藤 裕貴, 松居 喜郎

  日本心臓血管外科学会雑誌 (NPO)日本心臓血管外科学会 48 (6) 405 - 410 0285-1474 2019/11 [Refereed][Not invited]
   

  症例は60代女性。冠攣縮性狭心症で他院に通院加療中であった。経胸壁心エコー検査で左房内に心房中隔からバルサルバ洞後方の左房壁に至る広基性の可動性に富む腫瘍を指摘され、当院に紹介となった。CT検査やMRI検査の結果からは粘液腫が疑われた。手術は胸骨正中切開で行い、経心房中隔アプローチで左房腫瘍に到達した。左房内には同一の基部をもつ20×12×10mm大と40×30×15mm大の2つの腫瘍を認めた。粘液腫を念頭に約5mmのマージンを確保して腫瘍を切除した。小さい腫瘍は充実性で粘液腫を疑った。大きい腫瘍は乳頭状で、生理食塩水に浸したところイソギンチャク様の特徴的な形態を示したことから乳頭状線維弾性腫を疑った。ウシ心膜パッチを用いて心房中隔欠損部を補填した。病理診断では、小さい腫瘍は索状、管腔様構造を形成する腫瘍細胞を認め典型的な粘液腫の像を認めた。大きい腫瘍の乳頭状構造部分にはcalretinin染色に陽性を示す腫瘍細胞を少数認め、villous typeの粘液腫と診断された。術前検査や肉眼所見で両者を鑑別することは困難であり、判断に迷う場合はマージンを設けて全層切除するべきである。(著者抄録)
• 長期(3年以上)VAD治療の課題と対策 長期植込型補助人工心臓治療の現状、課題、そして対策

  大岡 智学, 加藤 伸康, 新宮 康栄, 若狭 哲, 加藤 裕貴, 松居 喜朗, 寒河江 磨, 矢萩 亮児, 櫛引 勝年, 加藤 美香

  人工臓器 (一社)日本人工臓器学会 48 (2) S - 75 0300-0818 2019/10
• Risk factors for residual mitral regurgitation after aortic valve replacement in patients with severe aortic valve stenosis and moderate mitral regurgitation.

  Yasushige Shingu, Hiroyuki Iwano, Tatsuya Murakami, Nobuyasu Katoh, Tomonori Ooka, Hiroki Katoh, Suguru Kubota, Yoshiro Matsui

  General thoracic and cardiovascular surgery 67 (10) 849 - 854 2019/10 [Refereed][Not invited]
   

  OBJECTIVES: While it was reported that patients with residual moderate mitral regurgitation (MR) after surgical aortic valve replacement (SAVR) had a poorer prognosis than those without it, the risk factors for residual MR have not been fully elucidated. The aim of the study was to evaluate risk factors for residual MR after SAVR. METHODS: Of the 222 patients who underwent isolated SAVR from 2001 to 2018, 33 (11 men; age: 74 ± 7 years) had functional moderate MR before surgery. The risk factors for residual MR were evaluated by comparing patients with residual moderate MR (n = 11, 33%) with those who exhibited improved post-surgery MR (n = 22, 67%). RESULTS: The left atrial diameter was significantly larger in the residual MR group (51 ± 7 mm) than in the improved MR group (46 ± 5 mm; P = 0.049). The mean pressure gradient at the aortic valve was significantly smaller in the residual MR group (52 ± 18 mmHg) than in the improved MR group (69 ± 22 mmHg; P = 0.043). A ratio of left atrial diameter (mm) and mean aortic valve pressure gradient (mmHg) greater than 0.9 predicted residual MR with a sensitivity of 70% and a specificity of 74% (area under the ROC curve: 0.779; P = 0.015). CONCLUSIONS: In patients with severe aortic valve stenosis and moderate MR, a high ratio of preoperative left atrial diameter and mean aortic valve pressure gradient would be a parameter predicting residual moderate MR post-SAVR.
• 修正大血管転位における肺動脈絞扼術の成績とDouble Switch Operationの要否

  谷口 宏太, 武田 充人, 辻岡 孝郎, 藤本 隆憲, 永井 礼子, 佐々木 理, 泉 岳, 山澤 弘州, 加藤 伸康, 橘 剛

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 35 (Suppl.1) s1 - 222 0911-1794 2019/06 [Not refereed][Not invited]
  
• フォンタン手術適応の大血管転位型心疾患に対する肺動脈絞扼術とBTシャント手術併用の有用性

  辻岡 孝郎, 藤本 隆憲, 谷口 宏太, 永井 礼子, 泉 岳, 佐々木 理, 山澤 弘州, 武田 充人, 新井 洋輔, 加藤 伸康, 橘 剛

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 35 (Suppl.1) s1 - 347 0911-1794 2019/06 [Not refereed][Not invited]
  
• 不整脈カテーテルアブレーション:治療困難症例に対する戦略 Fontan術後心房頻拍に対するアブレーション成功部位の電位的特徴

  泉 岳, 武田 充人, 山澤 弘州, 佐々木 理, 谷口 宏太, 佐々木 大輔, 藤本 隆憲, 辻岡 孝郎, 永井 礼子, 加藤 伸康, 新井 洋輔

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 35 (Suppl.1) s1 - 121 0911-1794 2019/06
• 体肺血管抵抗バランスの崩れたFontan患者における神経体液性因子の反応

  泉 岳, 山澤 弘州, 武田 充人, 佐々木 理, 谷口 宏太, 佐々木 大輔, 藤本 隆憲, 辻岡 孝郎, 永井 礼子, 加藤 伸康, 新井 洋輔

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 35 (Suppl.1) s1 - 196 0911-1794 2019/06
• 心外導管型Fontan conversionの治療成績と中遠隔期の効果

  加藤 伸康, 橘 剛, 新宮 康栄, 大岡 智学, 加藤 裕貴, 久保田 卓, 泉 学, 山澤 弘州, 武田 充人, 松居 喜郎

  日本外科学会定期学術集会抄録集 (一社)日本外科学会 119回 PS - 5 2019/04 [Refereed][Not invited]
  
• 乳児期・小児期に僧帽弁への手術介入を必要としたMarfan症候群4例の経験

  加藤 伸康, 橘 剛, 新宮 康栄, 大岡 智学, 加藤 裕貴, 久保田 卓, 山澤 弘州, 武田 充人, 松居 喜郎

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 49回 [PP - 011] 2019/02 [Refereed][Not invited]
  
• 先天性左冠動脈開口部閉鎖に対して左冠動脈主幹部再建を施行した2例

  新井 洋輔, 加藤 伸康, 橘 剛, 新宮 康栄, 大岡 智学, 加藤 裕貴, 久保田 卓, 武田 充人, 山澤 弘州, 泉 岳, 佐々木 理, 松居 喜郎

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 49回 [PP - 024] 2019/02 [Refereed][Not invited]
  
• 狭窄病変の定量における問題点と意義(Evaluation of stenotic lesions in the patient with ACHD)

  山澤 弘州, 武田 充人, 泉 岳, 佐々木 理, 谷口 宏太, 岩野 弘幸, 石森 直樹, 加藤 伸康

  日本成人先天性心疾患学会雑誌 8 (1) 97 - 97 2019/01 [Refereed][Not invited]
  
• 心外導管型フォンタンへの移行に加えて自己弁温存大動脈基部置換を併施した一例(A successful surgical case of extra-cardiac Fontan conversion combined with valve-sparing aortic root replacement for PA/IVS and aortic root aneurysm)

  加藤 伸康, 橘 剛, 新井 洋輔, 新宮 康栄, 加藤 裕貴, 大岡 智学, 久保田 卓, 泉 学, 山澤 弘州, 武田 充人, 松居 喜郎

  日本成人先天性心疾患学会雑誌 8 (1) 159 - 159 2019/01 [Refereed][Not invited]
  
• Cantrell症候群にDORV、AS、hypo archを合併した1例に対する外科治療経験

  伊藤 和, 橘 剛, 浅井 英嗣, 加藤 伸康, 藤本 隆憲, 阿部 二郎, 佐々木 理, 泉 岳, 山澤 弘州, 武田 充人, 松居 喜郎

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 34 (Suppl.1) s1 - 323 0911-1794 2018/07 [Refereed][Not invited]
  
• Marfan症候群に対する外科治療

  加藤 伸康, 橘 剛, 武田 充人, 山澤 弘州, 泉 岳, 佐々木 理, 阿部 二郎, 松居 喜郎

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 34 (Suppl.1) s1 - 328 0911-1794 2018/07 [Refereed][Not invited]
  
• 当院の心外導管型Fontan conversionの治療成績の検討

  加藤 伸康, 橘 剛, 浅井 英嗣, 新宮 康栄, 大岡 智学, 加藤 裕貴, 久保田 卓, 山澤 弘州, 武田 充人, 松居 喜郎

  日本心臓血管外科学会学術総会抄録集 (NPO)日本心臓血管外科学会 48回 716 - 716 2018/02 [Refereed][Not invited]
  
• Effects of blood flow dynamics on autologous pericardial degeneration in reconstructed pulmonary arteries.

  Nobuyasu Kato, Masaaki Yamagishi, Keiichi Itatani, Takako Miyazaki, Yoshinobu Maeda, Satoshi Asada, Yoshiro Matsui, Hitoshi Yaku

  Interactive cardiovascular and thoracic surgery 26 (2) 293 - 300 2018/02/01 [Refereed][Not invited]
   

  OBJECTIVES: To clarify the risk factors for abnormal degeneration of autologous pericardium, the mechanical stress on the endothelial tissue caused by turbulent blood flow in the pulmonary artery (PA) reconstructed with autologous pericardium and major aortopulmonary collateral arteries was assumed in pulmonary atresia and ventricular septal defect. METHODS: Patient-specific PA models were created for 6 patients based on their past computed tomography images taken after unifocalization of major aortopulmonary collateral arteries. Computational fluid dynamics models were created to simulate the physiological pulsatile flow including the peripheral reflection wave, characteristic impedance and autonomous regulation system. Flow streamline, wall shear stress (WSS) and the oscillatory shear index (OSI) were calculated from the simulated result. PA degeneration was evaluated with the computed tomography images before the intracardiac repair. RESULTS: Regions with physiological high WSS had fewer abnormal changes. Excessively high WSS was often detected at the anastomosis site of the reconstructed PA, and intimal thickening was found in these regions during intracardiac repair. Regions with high OSI and low WSS had dilated change within several months. In 1 patient, in particular, detached vortex flow occurred at the rectangular angle anastomosis site of the right PA in flow streamline, resulting in high OSI and low WSS with abnormal enlargement in the pericardium. CONCLUSIONS: Endothelial stress caused by blood flow would affect the degeneration of autologous pericardium and major aortopulmonary collateral arteries in the reconstructed PA. High OSI and low WSS might induce enlargement or dilatation, and excessively high WSS in the anastomosis site might induce intimal thickening.
• Ligation of Lumbar Arteries and Stent Graft-Conserving Aneurysmorrhaphy for Type II Endoleak

  Sato Koji, Matsui Yoshiro, Shingu Yasushige, Wakasa Satoru, Kato Nobuyasu, Seki Tatsuya, Ooka Tomonori, Kato Hiroki, Tachibana Tsuyoshi, Kubota Suguru

  Japanese Journal of Cardiovascular Surgery 特定非営利活動法人 日本心臓血管外科学会 47 (6) 257 - 262 0285-1474 2018 

  Background : Persistent endoleak is a major cause of aneurysmal enlargement or rupture after endovascular aneurysm repair (EVAR). Although several reports have described ligation of lumbar arteries and stent graft-conserving aneurysmorrhaphy as useful strategies, treatment for type II endoleak after EVAR is controversial. Objectives : We investigated the early results in 5 patients who underwent ligation of lumbar arteries and stent graft-conserving aneurysmorrhaphy for type II endoleak. Methods : A>10 mm increase in aneurysm diameter after primary EVAR or a maximum diameter>65 mm serve as indications for intervention for type II endoleak. Under general anesthesia, following transperitoneal exposure of the abdominal aorta, the infrarenal aorta was banded using a tape at the proximal landing zone. After the aorta was opened without clamping, the lumbar arteries were ligated, and a stent graft-conserving aneurysmorrhaphy was performed. Results : The mean interval from the primary EVAR was 47±17 months. The mean operation time was 215±76 min. Blood transfusion was necessary in 4 patients (estimated blood loss 1,260±710 ml). No in-hospital deaths were observed, and the mean postoperative hospital stay was 26±20 days. One patient developed aspiration pneumonia and 1 developed surgical site infection post-surgery. The diameter of the aneurysm changed from 68±8 to 47±5 mm during hospitalization and decreased further to 36±7 mm at the last follow-up. Conclusions : The early results of ligation of lumbar arteries and stent graft-conserving aneurysmorrhaphy were favorable. Although this strategy could be useful for aneurysmal dilatation secondary to persistent type II endoleak after EVAR, the indications for this approach should be determined following careful evaluation of the patient's status considering the invasiveness of the procedure.

• 肺動脈閉鎖症兼心室中隔欠損症に対するWaterston手術40年後の巨大肺動脈瘤に対する1治験例

  安東 悟央, 橘 剛, 加藤 伸康, 有村 聡士, 浅井 英嗣, 新宮 康栄, 若狭 哲, 加藤 裕貴, 大岡 智学, 松居 喜郎

  日本心臓血管外科学会雑誌 (NPO)日本心臓血管外科学会 47 (1) 13 - 17 0285-1474 2018/01 [Refereed][Not invited]
   

  非常に稀で、手術施行例の耐術例はほとんど報告がない、先天性心疾患姑息術後の肺動脈瘤の合併症例を経験した。症例は40代男性。肺動脈閉鎖症兼心室中隔欠損症に対して一歳時にWaterston手術を施行されたが、その後当時としては根治手術が困難と判断され、NYHA class I度のため数十年間近医で経過観察されていた。労作時の呼吸苦増悪を認め他院を受診、肺炎と心不全の疑いで入院加療されたが、胸部CT検査で95mmの右肺動脈瘤を認め、切迫破裂も疑われたため外科的加療目的に当科紹介となった。入院時、右胸水と右肺の広範な無気肺を認めた。胸水ドレナージを施行(800ml)した。胸水は漿液性で胸背部痛など認めず血行動態は安定していた。切迫破裂は否定的であったものの95mmと巨大な瘤径であり、利尿薬および抗生剤治療を数日間先行し、準緊急的に右肺動脈瘤に対して瘤切除および人工血管置換を施行した。術前NYHA I度であったことから、もともとの吻合部径や末梢の肺動脈径にならい24×12mm Y-graft人工血管を用いてcentral shuntとして肺動脈を再建した。PCPS装着のままICU入室、翌日離脱した。術後4日目に人工呼吸器離脱、術後38日目に退院となった。現在術後一年になるが、NYHA class I度で経過している。Waterston術後約40年後に発症した巨大肺動脈瘤に対し手術を施行し良好な結果を得たので報告する。(著者抄録)
• ファロー四徴症心内修復術におけるSkeletonization法を用いた肺動脈弁輪温存術式の術後成績

  佐々木 大輔, 阿部 二郎, 佐々木 理, 泉 岳, 山澤 弘州, 武田 充人, 加藤 伸康, 橘 剛

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 33 (Suppl.1) s1 - 190 0911-1794 2017/07 [Refereed][Not invited]
  
• 1生日に循環不全で発症したDORV, severe PS, cervical aortic arch, CoA, MAPCAの1例

  古川 夕里香, 橘 剛, 加藤 伸康, 松居 喜郎, 武田 充人, 山澤 弘州, 泉 岳, 佐々木 理

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 33 (Suppl.1) s1 - 193 0911-1794 2017/07 [Refereed][Not invited]
  
• 準緊急的に介入した未根治チアノーゼ性成人先天性心疾患症例の検討

  古川 夕里香, 橘 剛, 加藤 伸康, 松居 喜郎, 武田 充人, 山澤 弘州, 泉 岳, 佐々木 理

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 33 (Suppl.1) s1 - 397 0911-1794 2017/07 [Refereed][Not invited]
  
• 大血管転位症3型に対する当院の治療戦略 体肺動脈短絡術+短周径肺動脈絞扼術(BT-shunt with tight PAB)の有効性

  加藤 伸康, 橘 剛, 佐々木 理, 泉 岳, 山澤 弘州, 武田 充人, 新宮 康栄, 若狭 哲, 加藤 裕貴, 大岡 智学, 松居 喜郎

  日本小児循環器学会雑誌 (NPO)日本小児循環器学会 33 (Suppl.1) s1 - 224 0911-1794 2017/07
• 冠動脈肺動脈起始症(ACAPA)と冠動脈肺動脈瘻の治療経験

  安東 悟央, 大岡 智学, 古川 夕里香, 有村 聡士, 村瀬 亮太, 杉本 聡, 佐藤 公治, 加藤 伸康, 新宮 康栄, 若狭 哲, 橘 剛, 松居 喜郎, 太安 孝允, 加藤 裕貴

  北海道外科雑誌 北海道外科学会 62 (1) 80 - 80 0288-7509 2017/06
• Waterston術後数十年後に発見された巨大肺動脈瘤の1例

  安東 悟央, 有村 聡士, 加藤 伸康, 浅井 英嗣, 橘 剛, 松居 喜郎

  日本成人先天性心疾患学会雑誌 日本成人先天性心疾患学会 6 (1) 108 - 108 2017/01
• Smaller-Sized Expanded Polytetrafluoroethylene Conduits With a Fan-Shaped Valve and Bulging Sinuses for Right Ventricular Outflow Tract Reconstruction.

  Eijiro Yamashita, Masaaki Yamagishi, Takako Miyazaki, Yoshinobu Maeda, Yusuke Yamamoto, Nobuyasu Kato, Satoshi Asada, Hisayuki Hongu, Hitoshi Yaku

  The Annals of thoracic surgery 102 (4) 1336 - 44 2016/10 [Refereed][Not invited]
   

  BACKGROUND: One of the critical factors limiting conduit longevity in right ventricular outflow tract (RVOT) reconstruction with homografts and xenografts is the small size of the conduit. The aim of our study was to assess the outcome of using smaller-sized expanded polytetrafluoroethylene (ePTFE) conduits with a fan-shaped valve and bulging sinuses for RVOT reconstruction. METHODS: This retrospective review examined 303 patients who underwent RVOT reconstruction with ePTFE conduits at 63 Japanese hospitals between 2003 and 2014. Inclusion criteria were a conduit size less than or equal to 16 mm and the use of operative treatment as the primary correction for underlying heart disease. Patients undergoing palliative procedures were excluded. RESULTS: Median follow-up was 1.7 years. Freedom from conduit replacement and freedom from conduit reintervention were 90.1% ± 4.8% and 77.2% ± 5.6%, respectively. The most common indication for conduit reintervention was pulmonary artery (PA) bifurcation stenosis (82%). Modeling z-scores as a dichotomous variable revealed that freedom from conduit reintervention for PA bifurcation stenosis was significantly decreased for conduits with a z-score greater than or equal to 1.4 compared with z-scores less than 1.4 (p = 0.036). There were 30 patients (9.9%) who experienced at least moderate conduit stenosis and 21 patients (6.9%) with at least moderate conduit insufficiency. Univariate Cox regression analysis showed that conduit size was a significant factor for conduit stenosis (p = 0.006). CONCLUSIONS: Excellent midterm outcomes were achieved with ePTFE valved conduits, even when using smaller sizes. Conduit z-scores around 1.4 were optimal for RVOT reconstruction in younger patients.
• First Successful Clinical Application of the In Vivo Tissue-Engineered Autologous Vascular Graft.

  Nobuyasu Kato, Masaaki Yamagishi, Keiichi Kanda, Takako Miyazaki, Yoshinobu Maeda, Masashi Yamanami, Taiji Watanabe, Hitoshi Yaku

  The Annals of thoracic surgery 102 (4) 1387 - 90 2016/10 [Refereed][Not invited]
   

  PURPOSE: The ideal material for pediatric pulmonary artery (PA) augmentation is autologous pericardium. However, its utility for multistaged operations is limited. In this study, we applied an in vivo tissue-engineered autologous Biotube graft to a patient with congenital heart disease for the first time. DESCRIPTION: For molds of the Biotubes, two silicone 19F drain tubes were embedded in the subcutaneous spaces of a 2-year-old girl with a diagnosis of pulmonary atresia and ventricular septal defect with major aortopulmonary collateral arteries during palliative surgical procedures. When definitive repair was performed after 8 months, the implants were removed to prepare Biotubes, one of which was cut open and autologously implanted into the PA for patch augmentation. EVALUATION: Seven months after implantation, the Biotube patch-augmented PA tolerated balloon angioplasty (BAP) for residual stenosis of the peripheral PA. Computed tomography images after BAP showed the well-preserved shape of the Biotube patch-augmented PA. Neither aneurysm formation nor stenosis was observed. CONCLUSIONS: The safety and feasibility of Biotubes for pediatric PA patch augmentation are described. Because Biotubes are completely autologous, they may be ideal material for pediatric PA augmentation.
• A Novel Surgical Technique for Right-Sided Interrupted Aortic Arch by Interposition of a Pulmonary Autograft Tube.

  Nobuyasu Kato, Masaaki Yamagishi, Takako Miyazaki, Yoshinobu Maeda, Satoshi Asada, Hisayuki Hongu, Eijiro Yamashita, Hitoshi Yaku

  The Annals of thoracic surgery 102 (2) e125-7  2016/08 [Refereed][Not invited]
   

  Right-sided interrupted aortic arch (IAA) is a rare cardiac anomaly. In general, the right bronchus sits higher than the left bronchus, so aortic arch reconstruction with a direct anastomosis has a risk of tracheal and bronchial obstruction. This report describes the successful definitive repair of a right-sided IAA in a 2.5-kg neonate by aortic arch reconstruction with a pulmonary autograft tube (PA tube). Postoperative three-dimensional multidetector computed tomography showed the reconstructed aortic arch without airway obstruction or aortic stenosis. The use of a PA tube is a simple and useful technique for aortic arch reconstruction in patients with a high risk of tracheal andbronchial obstruction, such as right-sided IAA.
• 感染性大動脈瘤の診断におけるFDG-PETの有用性

  飯島 誠, 浅井 英嗣, 澁谷 千英子, 加藤 伸康, 南田 大朗, 夷岡 徳彦, 小林 一哉, 内藤 祐嗣, 松井 欣哉, 若狭 哲, 杉木 宏司, 大岡 智学, 橘 剛, 久保田 卓, 松居 喜郎

  北海道外科雑誌 北海道外科学会 56 (1) 69 - 70 0288-7509 2011/06
• 感染性大動脈瘤の診断におけるFDG-PETの有用性

  飯島 誠, 浅井 英嗣, 澁谷 千英子, 加藤 伸康, 南田 太朗, 小林 一哉, 内藤 祐嗣, 夷岡 徳彦, 松井 欣哉, 若狭 哲, 杉木 宏司, 大岡 智学, 橘 剛, 久保田 卓, 松居 喜郎

  日本血管外科学会雑誌 (NPO)日本血管外科学会 20 (2) 341 - 341 0918-6778 2011/04
• 当科における感染性胸腹部大動脈瘤の外科治療

  飯島 誠, 澁谷 千英子, 河合 昭浩, 加藤 伸康, 南田 大朗, 内藤 祐嗣, 夷岡 徳彦, 松井 欣哉, 若狭 哲, 杉木 宏司, 大岡 智学, 橘 剛, 久保田 卓, 松居 喜郎

  北海道外科雑誌 北海道外科学会 55 (2) 183 - 183 0288-7509 2010/12

MISC

• Surgical repair of a residual lesion of mixed-type total anomalous pulmonary venous connection using a vertical vein as a free graft: a case report(タイトル和訳中)

  Watabe Yoshinobu, Kato Nobuyasu, Niwano Haruki, Shingu Yasushige, Ooka Tomonori, Kato Hiroki, Abe Shinji, Wakasa Satoru  General Thoracic and Cardiovascular Surgery Cases  2-  1 of 5  -5 of 5  2023/08
• 特集 ファロー四徴症に対する外科治療 : 新生児期・幼少期から成人期まで—Surgery for tetralogy of Fallot from infancy to adulthood

  加藤 伸康, 阿部 慎司, 新宮 康栄, 加藤 裕貴, 大岡 智学, 若狭 哲  北海道外科雑誌 = The Hokkaido journal of surgery / 北海道外科雑誌編集委員会 編  67-  (1)  2  -9  2022/06
• 小児画像診断のコツ II.読影のコツ(マネージメントのコツ含む)4.心大血管におけるコツ 先天性心疾患

  常田慧徳, 加藤伸康, 武田充人  小児科診療  85-  2022
• 川崎病冠動脈障害に対する冠動脈バイパス術

  安東 悟央, 若狭 哲, 加藤 伸康, 新宮 康栄, 加藤 裕貴, 大岡 智学  日本冠疾患学会誌  (Suppl.2019)  179  -179  2019/12  [Not refereed][Not invited]
  
• カルニチンによる心臓弁膜症手術後の心房細動の予防(単群介入試験)

  新宮 康栄, 小市 裕太, 稗田 哲也, 新井 洋輔, 安東 悟央, 石垣 隆弘, 佐藤 公治, 加藤 伸康, 若狭 哲, 大岡 智学  北海道外科雑誌  64-  (2)  209  -209  2019/12  [Not refereed][Not invited]
  
• 肉眼的に乳頭状線維弾性腫と鑑別が困難であったvilloustype左房粘液腫の1例

  石垣 隆弘, 新宮 康栄, 加藤 伸康, 若狭 哲, 大岡 智学, 加藤 裕貴, 若林 健人, 三橋 智子, 松居 喜郎  北海道外科雑誌  64-  (2)  207  -207  2019/12  [Not refereed][Not invited]
  
• 長期(3年以上)VAD治療の課題と対策 長期植込型補助人工心臓治療の現状、課題、そして対策

  大岡 智学, 加藤 伸康, 新宮 康栄, 若狭 哲, 加藤 裕貴, 松居 喜朗, 寒河江 磨, 矢萩 亮児, 櫛引 勝年, 加藤 美香  人工臓器  48-  (2)  S  -75  2019/10  [Not refereed][Not invited]
  
• 左冠動脈閉鎖・僧帽弁閉鎖不全を合併した肺葉内肺分画症の1例

  本橋 雄介, 藤原 晶, 新垣 雅人, 加藤 達哉, 樋田 泰浩, 加賀 基知三, 新井 洋輔, 加藤 伸康, 橘 剛, 松居 喜郎  日本臨床外科学会雑誌  80-  (5)  1029  -1029  2019/05  [Not refereed][Not invited]
  
• 胸郭出口症候群に対する治療経験

  安東 悟央, 新宮 康栄, 石垣 隆弘, 村瀬 亮太, 杉本 聡, 関 達也, 加藤 伸康, 浅井 英嗣, 太安 孝允, 加藤 裕貴, 大岡 智学, 橘 剛, 久保田 卓, 松居 喜郎  脈管学  57-  (Suppl.)  S228  -S229  2017/10  [Not refereed][Not invited]
  
• TypeIIエンドリークに対するステントグラフト温存直達手術

  佐藤 公治, 新宮 康栄, 太安 孝允, 加藤 伸康, 若狭 哲, 大岡 智学, 加藤 裕貴, 橘 剛, 松居 喜郎  日本血管外科学会雑誌  26-  (Suppl.)  V4  -10  2017/06  [Not refereed][Not invited]
  
• 右冠動脈肺動脈起始症に対しreimplantation法、肺動脈欠損壁自己心膜パッチ形成術を施行した1例

  安東 悟央, 大岡 智学, 古川 夕里香, 村瀬 亮太, 杉本 聡, 佐藤 公治, 加藤 伸康, 浅井 英嗣, 太安 孝允, 新宮 康栄, 若狭 哲, 加藤 裕貴, 橘 剛, 松居 喜郎  日本血管外科学会雑誌  26-  (Suppl.)  P37  -8  2017/06  [Not refereed][Not invited]
  
• 心膜で再建された肺動脈の変性から見たPA/VSD/MAPCAsに対する段階的治療戦略の妥当性

  加藤 伸康, 山岸 正明, 板谷 慶一, 宮崎 隆子, 前田 吉宣, 浅田 聡, 藤田 周平, 本宮 久之, 夜久 均  日本心臓血管外科学会学術総会抄録集  47回-  191  -191  2017/02
• PA/VSD/MAPCAにおける自己心膜による中心肺動脈再建後の血流動態シミュレーション 中心肺動脈の形態変化・内膜変性のリスク因子を探る

  加藤 伸康, 板谷 慶一, 山岸 正明, 宮崎 隆子, 前田 吉宣, 浅田 聡, 本宮 久之, 夜久 均  日本小児循環器学会雑誌  32-  (Suppl.1)  s1  -276  2016/07
• fan-shaped ePTFE valved conduit with bulging sinusのさらなる進化を目指して 新型導管の有効性に関する検討

  山本 裕介, 山岸 正明, 宮崎 隆子, 前田 吉宣, 加藤 伸康, 浅田 聡  日本小児循環器学会雑誌  31-  (Suppl.1)  s1  -177  2015/07
• Heterotaxy syndromeを合併したFontan candidateの外科治療成績

  前田 吉宣, 山岸 正明, 宮崎 隆子, 山本 裕介, 加藤 伸康, 浅田 聡  日本小児循環器学会雑誌  31-  (Suppl.1)  s1  -275  2015/07
• 先天性心疾患 再手術回避のための治療戦略と工夫 心臓血管 先天性心疾患再手術回避のための手術術式の工夫

  山岸 正明, 宮崎 隆子, 前田 吉宣, 山本 裕介, 浅田 聡, 加藤 伸康, 山下 英次郎, 夜久 均  日本外科学会定期学術集会抄録集  115回-  SY  -2  2015/04
• MAPCA形態分類によるPA/VSD/MAPCAに対する治療戦略

  宮崎 隆子, 山岸 正明, 前田 吉宣, 山本 裕介, 加藤 伸康, 浅田 聡, 山下 英次郎, 夜久 均  日本心臓血管外科学会雑誌  44-  (Suppl.)  249  -249  2015/01
• 大血管関係transpotitionのFontan candidateは一側肺動脈閉塞のリスクとなる

  泉 岳, 武田 充人, 阿部 二郎, 古川 卓朗, 山澤 弘州, 武井 黄太, 浅井 英嗣, 加藤 伸康, 橘 剛  日本小児循環器学会雑誌  30-  (Suppl.)  s230  -s230  2014/06  [Not refereed][Not invited]
  
• 当科におけるTOFの肺動脈二尖弁に対する自己弁温存の術式と変遷

  加藤 伸康, 橘 鹿, 浅井 英嗣, 安東 悟央, 関 達也, 小林 一哉, 内藤 裕嗣, 新宮 康栄, 若狭 哲, 加藤 裕貴, 大岡 智学, 久保田 卓, 武田 充人, 松居 喜郎  日本心臓血管外科学会雑誌  43-  (Suppl.)  443  -443  2014/01  [Not refereed][Not invited]
  
• Fontan循環を目指す先天性心疾患における無機能右室に対する手術の工夫

  浅井 英嗣, 加藤 伸康, 橘 剛, 上野 倫彦, 武田 充人  日本小児循環器学会雑誌  29-  (Suppl.)  s176  -s176  2013/06  [Not refereed][Not invited]
  
• 当科で施行したTOF術後成人期(16歳以上)での再手術症例の検討

  KATO NOBUYASU, ASAI HIDETSUGU, SEKI TATSUYA, MINAMIDA TARO, IIJIMA MAKOTO, NAITO YUJI, SHINGU YASUSHIGE, WAKASA SATORU, OOKA TOMONORI, TACHIBANA TSUYOSHI, KUBOTA SUGURU, MATSUI YOSHIRO  日本成人先天性心疾患学会雑誌  2-  (1)  83  -83  2013/01  [Not refereed][Not invited]
  
• TCPC conversion時にextra cardiac routeにおける工夫と右室縫縮を施行した一例

  浅井 英嗣, 加藤 伸康, 若狭 哲, 大岡 智学, 橘 剛, 久保田 卓, 松居 喜郎, 古川 卓朗, 武井 黄太, 山澤 弘州, 武田 充人, 上野 倫彦  日本成人先天性心疾患学会雑誌  2-  (1)  109  -109  2013/01  [Not refereed][Not invited]