Researcher Database

KUGE Yuji
Central Institute of Isotope Science
Professor

Researcher Profile and Settings

Affiliation

  • Central Institute of Isotope Science

Job Title

    Professor

Research funding number

  • 70321958

Research Interests

  • inflammation   Radiopharmaceutical   Molecular Imaging   Nuclear Medicine   Pathofunctional Bioanalysis   

Research Areas

  • Pharmacy / Physical pharmacy
  • Clinical internal medicine / Radiation science

Education

  •        - 1987  Kyoto University  Graduate School, Division of Pharmaceutical Sciences  Division of Pharmacy and Biomedicinal Sciences  japan
  •        - 1985  Kyoto University  Faculty of Pharmaceutical Science  japan

Association Memberships

  • Japanese radioactive medicine science society   Japanese Society for Molecular Imaging   JAPANESE SOCIETY OF RADIATION SAFETY MANAGEMENT   The American Society of Nuclear Medicine   Cerebral Blood Flow and Metabolism   THE JAPANESE PHARMACOLOGICAL SOCIETY   THE PHARMACEUTICAL SOCIETY OF JAPAN   THE JAPANESE SOCIETY OF NUCLEAR MEDICINE   

Research Activities

Published Papers

Books etc

  • Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy
    Kuge Y, Shiga T, Tamaki N ()
    Springer 2016 Joint Editor
  • Semiconductor Detector-Based Scanners for Nuclear Medicine
    Takeuchi W, Suzuki A, Ueno Y, Shiga T, Hirata K, Okamoto S, Zhao S, Kuge Y, Kubo N, Kobayashi K, Watanabe S, Kobashi K, Umegaki K, Tamaki N (pp.51-65)
    Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. (Kuge Y, Shiga T, Tamaki N, eds.), Springer  2016 Joint Work
  • Development of a Microreactor for Synthesis of 18F-Labeled Positron Emission Tomography Probe
    Kuno N, Manri N, Abo N, Asano Y, Nishijima K, Tamaki N, Kuge Y (pp.113-124)
    Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. (Kuge Y, Shiga T, Tamaki N, eds.), Springer  2016 Joint Work
  • Preclinical Evaluation of a Thymidine Phosphorylase Imaging Probe, [123I]IIMU, for Translational Research
    Nishijima K, Zhao S, Feng F, Shimizu Y, Akizawa H, Ohkura K, Tamaki N, Kuge Y (pp.125-130)
    Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. (Kuge Y, Shiga T, Tamaki N, eds.), Springer  2016 Joint Work
  • Discovery and Evaluation of Biomarkers for Atherosclerosis
    Sakamoto T, Hanzawa H, Manri N, Sakakibara M, Shimizu Y, Zhao Y, Zhao S, Yamada S, Kamiya K, Eki Y, Suzuki A, Higuchi H, Sugano C, Tsutsui H, Tamaki N, Kuge Y (pp.131-139)
    Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. (Kuge Y, Shiga T, Tamaki N, eds.), Springer  2016 Joint Work
  • Radioimmunodetection of Atherosclerotic Lesions Focusing on the Accumulation Mechanism of Immunoglobulin G
    Shimizu Y, Hanzawa H, Zhao Y, Nishijima K, Fukura S, Sakamoto T, Zhao S, Tamaki N, Kuge Y (pp.141-150)
    Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. (Kuge Y, Shiga T, Tamaki N, eds.), Springer  2016 Joint Work
  • Molecular imaging for integrated medical therapy and drug development
    Tamaki N, Kuge Y ()
    Springer 2010 Joint Editor
  • Advances in Molecular Imaging
    Tamaki N, Kuge Y (pp.1-4)
    Molecular imaging for integrated medical therapy and drug development. (Tamaki N, Kuge Y, eds), Springer  2010 Joint Work
  • Molecular Imaging for the Assessment of Tumor Malignancy and Response to Therapy
    Kuge Y, Zhao S, Takei T, Tamaki N (pp.19-29)
    Molecular imaging for integrated medical therapy and drug development. (Tamaki N, Kuge Y, eds), Springer  2010 Joint Work
  • Initial Performance Measurement of an Integrated PET/SPECT/CT System for Small Animal Imaging
    Magota K, Kubo N, Narihiro K, Suzuki K, Nishijima K, Zhao S, Kuge Y, TamakiN (pp.60-68)
    Molecular imaging for integrated medical therapy and drug development. (Tamaki N, Kuge Y, eds), Springer  2010 Joint Work
  • Molecular Imaging of Atherosclerotic Plaque Vulnerability: Comparison between 18F-FDG and 99mTc-Annexin A5
    Zhao Y, Kuge Y, Zhao S, Strauss HW, Blankenberg FG, Tamaki N (pp.69-77)
    Molecular imaging for integrated medical therapy and drug development. (Tamaki N, Kuge Y, eds), Springer  2010 Joint Work
  • Bone Marrow Stromal Cell Transplantation for Central Nervous System Disorders ?Perspective for Translational Research and Clinical Application
    Kuroda S, Kuge Y, Tamaki N, Iwasaki Y (pp.126-138)
    Molecular imaging for integrated medical therapy and drug development. (Tamaki N, Kuge Y, eds), Springer  2010 Joint Work
  • Non-invasive Optical Tracking of Bone Marrow Stromal Cells Transplanted into Rat Cerebral Infarct
    Sugiyama T, Kuroda S, Osanai T, Maruichi K, Chiba Y, Shichinohe H, Kuge Y, Tamaki N, Iwasaki Y (pp.139-144)
    Molecular imaging for integrated medical therapy and drug development. (Tamaki N, Kuge Y, eds), Springer  2010 Joint Work
  • IAEA RADIOISOTOPES AND RADIOPHARMACEUTICALS SERIES No. 1. Technetium-99m Radiopharmaceuticals: Status and Trends. Chapter 11 Technetium-99m Annexin-A5 for Apoptosis Imaging
    Kuge Y (pp.241-253)
    INTERNATIONAL ATOMIC ENERGY AGENCY 2009 Contributor
  • Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives
    Tamaki N, Kuge Y ()
    International Congress Series 1264, Elsevier Science B.V 2004 Joint Editor
  • Clinical Nuclear Cardiology --State of the Art and Future Directions-- (3rd Edition) Section VIII Tracer Specific Imaging Technique, Chapter 35 Fatty Acid Imaging
    Tamaki N, Morita K, Kuge Y (pp.559-575)
    Elsevier 2004 Contributor
  • Analysis of Neuronal and Glial Functions in Cerebral Ischemia: An Approach with Nuclear Medicine.
    Kuge Y, Kaji T, Hikosaka K, Yokota C, Seki K, Ohkura K, Shiga T, Minematsu K, Tamaki N (pp.44-52)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • The loss of neuronal integrity may be one of the causes of cognitive disturbances in the patients with brain traumatic injury and normal FLAIR and T2-weighted MRI.
    Shiga T, Ikoma K, Tsukamoto M, Katoh C, Matsuyama T, Kuge Y, Nakada K, Tamaki N (pp.177-180)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • Neuronal cyclooxygenase-2 induction associated with spreading depression and focal brain ischemia in primates.
    Yokota C, Kuge Y, Hasegawa Y, Inoue H, Tagaya M, Abumiya T, Kito G, Tamaki N, Minematsu K (pp.191-196)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • Methionine PET in differentiating recurrent brain tumor from radiation necrosis following cranial radiation.
    Katoh N, Nakada K, Takei N, Aoyama H, Shirato H, Kato C, Kuge Y, Tsukamoto E, Tamaki N (pp.217-221)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • Time course of apoptotic tumor response following a single dose of chemotherapy: Detection with 99mTc-annexin V and comparison with blood flow, caspase-3 expression and TUNEL staining in an experimental tumor model.
    Takei T, Kuge Y, Zhao S, Mochizuki T, Strauss HW, Blankenberg F, Tait JF, Tamaki N (pp.249-252)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • The impact of coronary stenosis and risk factors on myocardial flow reserve.
    Tsukamoto T, Morita K, Noriyasu K, Katoh C, Kageyama H, Mabuchi K, Kuge Y, Nakada K, Okamoto H, Kitabatake A, Tamaki N (pp.257-260)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • In vitro and in vivo characterization of high specific activity S-(-) [11C]CGP-12177, a radioligand for β-adrenoceptors, in rats.
    Nishijima K, Kuge Y, Motoki N, Seki K, Ohkura K, Morita K, Tamaki N (pp.261-266)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • Reduction of myocardial oxidative metabolism in dilated cardiomyopathy but not in remote areas in myocardial infarction.
    Noriyasu K, Tsukamoto T, Morita K, Kageyama H, Mabuchi M, Katoh C, Kuge Y, Kitabatake A, Tamaki N (pp.271-274)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • An ultra-high-energy collimator for small animal imaging in dual-isotope study of 18F and 99mTc.
    Kubo N, Zhao S, Kinda A, Motomura N, Katoh C, Kuge Y, Tamaki N (pp.275-279)
    Positron Emission Tomography and Molecular Imaging: State of the Art and Future Perspectives, International Congress Series 1264 (Y. Kuge, N. Tamaki, eds), Elsevier Science B.V 2004 Joint Work
  • Brain ischemia and spreading depression in a primate model.
    Yokota C, Kuge Y, Tagaya M, Hasegawa Y, Abumiya T, Kito G, Yamaguchi T, Minematsu K (pp.127-144)
    Strategic medical science against brain attack (Kikuchi H, ed.), Springer-Verlag 2002 Joint Work
  • Positron Emission Tomography in the Millennium
    Tamaki N, Tsukamoto E, Kuge Y, Katoh C, Morita K ()
    International Congress Series 1197, Elsevier Science B.V 2000 Joint Editor
  • Clinical Utility of Combination of FDG-PET and CBF-SPECT in Extratemporal Lobe Epilepsy
    Takano A, Shiga T, Kobayashi J, Nakamura F, Adachi I, Katoh C, Kuge Y, Koyama T, Tsukamoto E, Tamaki N (pp. 73-78)
    Positron Emission Tomography in the Millennium”, International Congress Series 1197 (Tamaki N, Tsukamoto E, Kuge Y, Katoh C, Morita K, eds.), Elsevier Science B.V. 2000 Joint Work
  • Quantitative Analysis for Myocardial Glucose Utilization Using Positron Emission Tomography and F-18-Deoxyglucose
    Morita K, Katoh C, Yoshinaga K, Adachi I, Shiga T, Mabuchi M, Itoh Y, Konno M, Kohya T, Kitabatake A, Kuge Y, Tsukamoto E, Tamaki N (pp. 141-145)
    Positron Emission Tomography in the Millennium”, International Congress Series 1197 (Tamaki N, Tsukamoto E, Kuge Y, Katoh C, Morita K, eds.), Elsevier Science B.V. 2000 Joint Work
  • Clinical Usefulness of FDC-PET in the Patients with Differentiated Thyroid Cancer after Total Thyroidectomy
    Shiga T, Tsukamoto E, Kato T, Morita K, Adachi I, Mabuchi M, Yoshinaga K, Suginami Y, Takano A, Tamaki N, Katoh C, Kuge Y (pp. 181-185)
    Positron Emission Tomography in the Millennium”, International Congress Series 1197 (Tamaki N, Tsukamoto E, Kuge Y, Katoh C, Morita K, eds.), Elsevier Science B.V. 2000 Joint Work
  • Visualization of Normal Organs in Whole-Body PET Imaging with F-18 FDG
    Kato T, Tsukamoto E, Suginami Y, Mabuchi M, Yoshinaga K, Takano A, Adachi I, Shiga T, Morita K, Katoh C, Kuge Y, Tamaki N (pp.221-224)
    Positron Emission Tomography in the Millennium”, International Congress Series 1197 (Tamaki N, Tsukamoto E, Kuge Y, Katoh C, Morita K, eds.), Elsevier Science B.V. 2000 Joint Work
  • Modified Method for Quantifying Regional Myocardial Blood Flow Using 15O-water with PET
    Katoh C, Kuge Y, Morita K, Tsukamoto E, Tamaki N, Knuuti J (pp. 273-278)
    Positron Emission Tomography in the Millennium”, International Congress Series 1197 (Tamaki N, Tsukamoto E, Kuge Y, Katoh C, Morita K, eds.), Elsevier Science B.V. 2000 Joint Work
  • Animal PET Study in Development of Novel PET Tracers.
    Kuge Y, Kawashima H, Ejima N, Miyake Y, Hashimoto N, Hashimoto T, Imanishi M, Shiomi M, Minematsu K, Hasegawa Y, Yamaguchi T, Tamaki N (pp.297-304)
    Positron Emission Tomography in the Millennium”, International Congress Series 1197 (Tamaki N, Tsukamoto E, Kuge Y, Katoh C, Morita K, eds.), Elsevier Science B.V. 2000 Joint Work

MISC

  • Imaging modalities for drug-related osteonecrosis of the jaw (3), Positron emission tomography imaging for the diagnosis of medication-related osteonecrosis of the jaw.
    Kitagawa Y, Ohga N, Asaka T, Sato J, Hata H, Helman J, Tsuboi K, Amizuka N, Kuge Y, Shiga T  Jpn Dent Sci Rev.  55-  (1)  65  -67  2019   [Not refereed] [Invited]
  • The Roles of Hypoxia Imaging Using 18F-Fluoromisonidazole Positron Emission Tomography in Glioma Treatment.
    Hirata K, Yamaguchi S, Shiga T, Kuge Y, Tamaki N  J Clin Med.  8-  (8)  E1088  2019   [Refereed] [Invited]
  • Shimizu Y, Kuge Y  Nuclear Medicine and Molecular Imaging  50-  (4)  284  -291  2016   [Refereed] [Invited]
  • Molecular imaging in heart failure patients
    Tamaki N, Kuge Y, Yoshinaga K  Clin Transl Imaging  1-  (5)  341  -354  2013   [Not refereed] [Invited]
  • Kuge Y, Zhao S, Takei T, Tamaki N  Anti-Cancer Agents in Medicinal Chemistry  9-  1003  -1011  2009   [Refereed] [Invited]
  • Myocardial metabolic imaging in the clinical setting
    Tamaki N, Kuge Y, Yoshinaga K  Eur Cardiolgy  5-  (1)  15  -18  2009   [Not refereed] [Invited]
  • What is the clinical role of neuronal imaging? (INVITED COMMENTARY)
    Morita K, Kuge Y, Tamaki N  J Nucl Med  44-  (9)  1467  -1468  2003   [Not refereed] [Invited]
  • Tamaki N, Kuge Y, Katoh C  Nucl Med Com  22-  (8)  847  -850  2001   [Not refereed] [Invited]
  • Clinical roles of perfusion and metabolic imaging.
    Tamaki N, Kuge Y, Tsukamoto E  J Cardiol  37-  (Suppl I)  57  -64  2001   [Not refereed] [Invited]
  • The Road to Quantitation of Regional Myocardial Uptake of Tracer (INVITED COMMENTARY)
    Tamaki N, Kuge Y, Tsukamoto E  J Nucl Med  42-  780  -781  2001   [Not refereed] [Invited]
  • The role of fatty acids in cardiac imaging.
    Tamaki N, Morita K, Kuge Y, Tsukamoto E  J Nucl Med  41-  (9)  1525  -1534  2000   [Not refereed] [Invited]
  • Effects of Extracranial Radioactivity on Measurement of Cerebral Glucose Metabolism by Rat-PET with [18F]-2-fluoro-2-deoxy-D-glucose (Letter to the editor)
    Kuge Y, Miyake Y, Minematsu K, Yamaguchi T, Hasegawa Y  J. Cereb. Blood Flow Metab  17-  1261  1997   [Not refereed] [Not invited]

Awards & Honors

  • 2002   The 40th award of the Japanese Society of Nuclear Medicine
       japan

Research Grants & Projects

  • Ministry of Education, Culture, Sports, Science and Technology:Grants-in-Aid for Scientific Research(基盤研究(B))
    Date (from‐to) : 2008 -2010 
    Author : Yuji KUGE
     
    In the present study, we utilized molecular imaging technology that visualized tumor proliferation and hypoxia, and demonstrated the usefulness in the analyses of tumor pathological states and response to molecular-targeted/radiation therapies, in animal models and clinical settings. We also demonstrated, in animal models, potentials and safety profiles of our novel candidate compound for angiogenesis imaging. The present results could provide important evidences to develop novel diagnosis and treatment strategy taking advantages of molecular imaging technology that visualizes alteration in tumor pathological states at molecular/cellular levels.
  • Ministry of Education, Culture, Sports, Science and Technology:Grants-in-Aid for Scientific Research(基盤研究(B))
    Date (from‐to) : 2005 -2007 
    Author : Yuji KUGE
     
    Using positron emission tomography, we attempted to developed molecular imaging strategies that enable in vivo imaging of molecular mechanisms and/or characteristics of tumors, in order to contribute to personalized therapy of cancer patients. The results in the present study can be summarized as follows:1. Studies on molecular-targeted therapyIn our animal model, ^<18>F-FLT (a marker of DNA synthesis) can early detect the antiproliferative effects of the molecular-targeting therapy with gefitinib before significant changes in the tumor size, indicating the potential of FLT-PET in early monitoring of tumor response to the molecular-targeting therapy.2. Studies on radiation therapyThe results in an animal model indicated that post-radiation therapy response may be predicted by the accumulation of ^<18>F-FDG before complicated change, such as inflammation following irradiation, occurs.3. Development of molecular imaging probes that target molecular mechanisms of tumors.(1) For developing a thymidine phosphorylase (TP)-expression-based molecular imaging probe, we synthesized novel C-11 and I-123 labeled uracil derivatives, which were designed on the basis of one of the potent TP-inhibitors. The compounds synthesized possessed similar inhibitory potentials to the mother compounds.(2) A radioiodinated celecoxib derivative, ^<125I>-IMTP was synthesized. Our results showed a high inhibitory potency and selectivity of IMTP for COX-2, indicating its potential as a SPECT tracer for imaging cyclooxygenase-2 expression. In addition, we succeed to synthesizing a radioiodinated lumiracoxib derivative with reduced nonspecific bindings.(3) [^<99m>Tc-labeled anti-MT1-MMP (membrane-type-1 MMP) antibody accumulated in the tumor in time-dependent manner, indicating the potential of the labeled antibody for the imaging agent of tumor malignancy. In addition, the pre-targeting strategy improved S/N ratios.
  • Ministry of Education, Culture, Sports, Science and Technology:Grants-in-Aid for Scientific Research(基盤研究(B))
    Date (from‐to) : 2002 -2004 
    Author : Yuji KUGE
     
    In order to clarify 1)the roles of cyclooxygenase-2(COX-2) in the pathophysiology of cerebral ischemia and 2)the potentials of COX-2 molecular imaging in the patho-functional analysis of the disease, we planed the present project using molecular imaging technique. Our findings in this project were as follows :1.Temporal changes of cerebral blood flow, metabolism, and neuro-receptor in animal models of cerebral ischemiaIn ischemic regions where neuro-receptor function was preserved, neuronal DNA is still intact and cellular integrity is maintained. COX-2 expression was often observed in these regions.2.Cyclooxygenase-2 expression in animal models of stroke(1)The time course of COX-2 mRNA expression in the ischemic core was different from that of the peri-infarct area. The expression of COX-2 in focal ischemic tissues is determined by the depth and duration of CBF reduction.(2)Upregulation of bilateral S-100A9 and ipsi-lateral IL-1β and IL-6 genes, induced by the Spreading Depression(SD) elicitation were demonstrated to be downregulated by a selective COX-2 inhibitor JTE-522.3.Development of molecular probes for imaging COX-2 expressionWe intended to develop a radioiodinated coxib as a SPECT tracer for imaging COX-2 expression and designed 5-(4-iodophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole (IMTP). ^<125>I-IMTP was successfully synthesized with a high specific activity. Our results showed a high inhibitory potency and selectivity of IMTP for COX-2, indicating its potential as a SPECT tracer for imaging COX-2 expression.

Educational Activities

Teaching Experience

  • 医学研究概論
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • Research and Development of Medical Devices
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医理工学院
    キーワード : 医療機器、医学物理、画像診断、機能診断、放射線治療、粒子線治療 Medical device, Medical physics, Medical imaging, Functional Imaging, Radiation therapy, Particle beam therapy
  • 研究発表技法Ⅰ
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • Radiation Protection for Biomedical Science and Engineering
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医理工学院
    キーワード : 放射線防護、国際的基準、国内法令、被ばく線量、リスク、安全取扱 Radiation Protection, International Standard, National Law, Exposed Dose, Risk, Safe Handling
  • 研究発表技法Ⅱ
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • Basic Principles of Medicine
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医学院
    キーワード : 分子イメージング・トレーサー・病態分析・薬物の体内動態 Molecular Imaging/Tracer/Patho-Functional Bioanalysis/Parmacokinetics
  • 基盤医学研究Ⅰ
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • General Research on Biomedical Science and Engineering I
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医理工学院
    キーワード : 分子プローブ、機能分子探索、プローブ合成・合成装置、病態分析、トランスレーション Molecular Probe, Bio-functional molecules, Synthesis and Synthetic Apparatus, Patho-Functional Bioanalysis, Translational Research
  • 基盤医学研究Ⅱ
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • General Research on Biomedical Science and Engineering II
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医理工学院
    キーワード : 分子プローブ、機能分子探索、プローブ合成・合成装置、病態分析、トランスレーション Molecular Probe, Bio-functional molecules, Synthesis and Synthetic Apparatus, Patho-Functional Bioanalysis, Translational Research
  • 臨床医学研究Ⅰ
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • Molecular Probe Science
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医理工学院
    キーワード : 分子プローブ、核医学(PET、SPECT)分子プローブ、放射性同位元素の製造、標識反応、自動合成装置 Molecular Probe, Nuclear Medicine (PET, SPECT) Probe, Production of Radioisotope, Radiolabeling Reaction, Automated Synthetic Apparatus,
  • 臨床医学研究Ⅱ
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • Master's Thesis Research in Medical Sciences
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医学院
    キーワード : ラジオアイソトープ,核医学,画像診断
  • 医学総論
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学研究科
  • Basic Principles of Medicine
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医学院
    キーワード : 放射性同位元素,分子バイオイメージング,PET radioisotope, molecular imaging, PET
  • Basic Principles of Medicine
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医学院
    キーワード : 分子イメージング,分子プローブ,トレーサー,分子・細胞機能 molecular imaging, molecular prove, tracer
  • Introduction to Biomedical Science and Engineering Research
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医理工学院
    キーワード : 動物実験、図書館、電子ジャーナル、共同利用施設、RI実験 Animal experiments, library, electric journals, common facilities, radioisotopic experiments
  • Introduction to Basic Medical Research
    開講年度 : 2017
    課程区分 : 修士課程
    開講学部 : 医学院
    キーワード : 動物実験、図書館、電子ジャーナル、共同利用施設、RI実験 Animal experiments, library, electric journals, common facilities, radioisotopic experiments
  • Principles of Medicine
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学院
    キーワード : トレーサー(分子プローブ)・生体機能/病態分析・マイクロドージング Tracer(Molecular Probe)/Patho-Functional Bioanalysis/Micro-dosing
  • Advanced Research on Biomedical Science and Engineering I
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医理工学院
    キーワード : 分子プローブ、機能分子探索、プローブ合成・合成装置、病態分析、トランスレーション Molecular Probe, Bio-functional molecules, Synthesis and Synthetic Apparatus, Patho-Functional Bioanalysis, Translational Research
  • Advanced Research on Biomedical Science and Engineering II
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医理工学院
    キーワード : 分子プローブ、機能分子探索、プローブ合成・合成装置、病態分析、トランスレーション Molecular Probe, Bio-functional molecules, Synthesis and Synthetic Apparatus, Patho-Functional Bioanalysis, Translational Research
  • Principles of Medicine
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学院
    キーワード : 放射性同位元素,分子バイオイメージング,PET,アイソトープ治療 radioisotope, PET
  • Principles of Medicine
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学院
    キーワード : 分子イメージング,分子プローブ,トレーサー,分子・細胞機能 molecular imaging, molecular prove, tracer
  • Dissertation Research in Medical Sciences
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学院
    キーワード : ラジオアイソトープ,核医学,画像診断 radioisotope, nuclear medicine, diagnostic imaging
  • Dissertation Research in Clinical Medicine
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学院
    キーワード : ラジオアイソトープ,核医学,画像診断 radioisotope, nuclear medicine, diagnostic imaging
  • Principles of Medicine
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学院
    キーワード : radiology,nuclear medicine,radiation oncology,English
  • Introduction to Medical Research
    開講年度 : 2017
    課程区分 : 博士後期課程
    開講学部 : 医学院
    キーワード : 動物実験、図書館、電子ジャーナル、共同利用施設、RI実験 Animal experiments, library, electric journals, common facilities, radioisotopic experiments
  • Health and Society
    開講年度 : 2017
    課程区分 : 学士課程
    開講学部 : 全学教育
    キーワード : アイソトープ・放射線の基礎, 社会生活に密接にかかわるアイソトープ・放射線, 先端医療におけるアイソトープ・放射線の利用,

Committee Membership

  • 2013 - Today   Japanese Society for Molecular Imaging   Director
  • 2013 - Today   The Japanese Society of Cerebral Blood Flow & Metabolism   Manager   The Japanese Society of Cerebral Blood Flow & Metabolism
  • 2011 - Today   Universities and other radiation facility Council   Director
  • 2010 - Today   Japanese Society of Radiation Safety Management   Director
  • 2001 - Today   The Japanese Society of Nuclear Medicine   Councilor   The Japanese Society of Nuclear Medicine


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