Researcher Database

Akihiro SUZUKI
Research Institute for Electronic Science Photonics and Optical Science
Assistant Professor

Researcher Profile and Settings


  • Research Institute for Electronic Science Photonics and Optical Science

Job Title

  • Assistant Professor

Research funding number

  • 20781850

J-Global ID

Research Interests

  • Ptychography   Coherent diffraction imaging   X-ray microscopy   

Research Areas

  • Nanotechnology/Materials / Nanobioscience

Academic & Professional Experience

  • 2016/04 - Today Hokkaido University Research Institute for Electronic Science
  • 2013/04 - 2016/03 日本学術振興会 特別研究員(DC1)


  • 2013/04 - 2016/03  Osaka University  Graduate School of Engineering  Division of Precision Science & Technology and Applied Physics
  • 2011/04 - 2013/03  Osaka University  Graduate School of Engineering  Division of Precision Science & Technology and Applied Physics
  • 2007/04 - 2011/03  Osaka University  School of Engineering  Department of Applied Science

Association Memberships


Research Activities

Published Papers

  • Takashi Kimura, Akihiro Suzuki, Ying Yang, Yoshiya Niida, Akiko Nishioka, Masashi Takei, Jinjian Wei, Hideyuki Mitomo, Yasutaka Matsuo, Kenichi Niikura, Kuniharu Ijiro, Kensuke Tono, Makina Yabashi, Tetsuya Ishikawa, Tairo Oshima, Yoshitaka Bessho, Yasumasa Joti, Yoshinori Nishino
    Review of Scientific Instruments 91 (8) 083706 - 083706 0034-6748 2020/08/01 [Refereed][Not invited]
  • Chi-Feng Huang, Wei-Hau Chang, Ting-Kuo Lee, Yasumasa Joti, Yoshinori Nishino, Takashi Kimura, Akihiro Suzuki, Yoshitaka Bessho, Tsung-Tse Lee, Mei-Chun Chen, Shun-Min Yang, Yeukuang Hwu, Shih-Hsin Huang, Po-Nan Li, Peilin Chen, Yung-Chieh Tseng, Che Ma, Tsui-Ling Hsu, Chi-Huey Wong, Kensuke Tono, Tetsuya Ishikawa, Keng S. Liang
    AIP Advances 10 (055219) 055219-1 - 055219-11 2020/05/20 [Refereed][Not invited]
  • Yoko Takeo, Akihiro Suzuki, Hiroto Motoyama, Yoshinori Takei, Takehiro Kume, Yusuke Matsuzawa, Yasunori Senba, Hikaru Kishimoto, Haruhiko Ohashi, Hidekazu Mimura
    Applied Physics Letters 116 (12) 121102-1 - 121102-4 2020/03 [Refereed][Not invited]
  • Akihiro Suzuki, Takashi Kimura, Ying Yang, Yoshiya Niida, Akiko Nishioka, Tatsuro Tachibana, Masashi Takei, Kensuke Tono, Makina Yabashi, Tetsuya Ishikawa, Tairo Oshima, Yoshitaka Bessho, Yasumasa Joti, Yoshinori Nishino
    Physical Chemistry Chemical Physics 22 2622 - 2628 2020/02 [Refereed][Not invited]
  • T. Koyama, H. Yumoto, T. Kimura, A Suzuki, T. Kameshima, Y. Joti, K. Tono, N. Tani, T. Tachibana, Y. Konishi, Y. Bessho, Y. Nishino, M. Yabashi, H. Ohashi
    Microscopy and Microanalysis 24 294 - 295 2018 [Refereed][Not invited]
  • Akihiro Suzuki, Kei Shimomura, Makoto Hirose, Nicolas Burdet, Yukio Takahashi
    SCIENTIFIC REPORTS 6 35060  2045-2322 2016/10 [Refereed][Not invited]
    The phase shift of light or electrons in objects is now necessary for probing weak-phase objects such as unstained biological specimens. Optical microscopy (OM) and transmission electron microscopy (TEM) have been used to observe weak-phase objects. However, conventional OM has low spatial resolution and TEM is limited to thin specimens. Here, we report on the development of dark-field X-ray ptychography, which combines X-ray ptychography and X-ray in-line holography, to observe weak-phase objects with a phase resolution better than 0.01 rad, a spatial resolution better than 15 nm, and a field of view larger than 5 mu m. We apply this method to the observation of both the outline and magnetosomes of the magnetotactic bacteria MO-1. Observation of thick samples with high resolution is expected to find broad applications in not only biology but also materials science.
  • Makoto Hirose, Kei Shimomura, Akihiro Suzuki, Nicolas Burdet, Yukio Takahashi
    OPTICS EXPRESS 24 (11) 1917 - 1925 1094-4087 2016/05 [Refereed][Not invited]
    The sample size must be less than the diffraction-limited focal spot size of the incident beam in single-shot coherent X-ray diffraction imaging (CXDI) based on a diffract-before-destruction scheme using X-ray free electron lasers (XFELs). This is currently a major limitation preventing its wider applications. We here propose multiple defocused CXDI, in which isolated objects are sequentially illuminated with a divergent beam larger than the objects and the coherent diffraction pattern of each object is recorded. This method can simultaneously reconstruct both objects and a probe from the coherent X-ray diffraction patterns without any a priori knowledge. We performed a computer simulation of the prposed method and then successfully demonstrated it in a proof-of-principle experiment at SPring-8. The prposed method allows us to not only observe broad samples but also characterize focused XFEL beams. (C) 2016 Optical Society of America
  • Nicolas Burdet, Kei Shimomura, Makoto Hirose, Akihiro Suzuki, Yukio Takahashi
    APPLIED PHYSICS LETTERS 108 (7) 071103-1 - 5 0003-6951 2016/02 [Refereed][Not invited]
    The efficient use of coherent X-rays is a crucial issue for ptychography at synchrotron facilities. We propose a method for optimizing the population of coherent modes for an optimal resolution. We show by a wave optical simulation that the intensity of a nearly diffraction-limited focusing X-ray beam can be described as an incoherent sum of a few orthogonal modes and that the first-mode flux significantly increases within a secondary source size by relaxing the requirement on the degree of coherence. We experimentally demonstrate it by means of multiple-mode ptychography with a synchrotron X-ray and achieve the high-resolution imaging of a weak-phase object. The present approach enables the high-resolution and high-throughput observation of weak-phase objects in materials science and biology. (C) 2016 Author(s).
  • Z. Huang, M. Bartels, R. Xu, M. Osterhoff, S. Kalbfleisch, M. Sprung, A. Suzuki, Y. Takahashi, T. N. Blanton, T. Salditt, J. Miao
    Nature Materials 14 691 - 695 2015 [Refereed][Not invited]
  • K. Shimomura, A. Suzuki, M. Hirose, Y. Takahashi
    Physical Review B 91 214114-1 - 5 2015 [Refereed][Not invited]
  • A. Suzuki, Y. Takahashi
    Optics Express 23 16429 - 16438 2015 [Refereed][Not invited]
  • Rui Xu, Huaidong Jiang, Changyong Song, Jose A. Rodriguez, Zhifeng Huang, Chien-Chun Chen, Daewoong Nam, Jaehyun Park, Marcus Gallagher-Jones, Sangsoo Kim, Sunam Kim, Akihiro Suzuki, Yuki Takayama, Tomotaka Oroguchi, Yukio Takahashi, Jiadong Fan, Yunfei Zou, Takaki Hatsui, Yuichi Inubushi, Takashi Kameshima, Koji Yonekura, Kensuke Tono, Tadashi Togashi, Takahiro Sato, Masaki Yamamoto, Masayoshi Nakasako, Makina Yabashi, Tetsuya Ishikawa, Jianwei Miao
    NATURE COMMUNICATIONS 5 4061-1 - 9 2041-1723 2014/06 [Refereed][Not invited]
    Conventional three-dimensional (3D) structure determination methods require either multiple measurements at different sample orientations or a collection of serial sections through a sample. Here we report the experimental demonstration of single-shot 3D structure determination of an object; in this case, individual gold nanocrystals at similar to 5.5 nm resolution using similar to 10 fs X-ray free-electron laser pulses. Coherent diffraction patterns are collected from high-index-faceted nanocrystals, each struck by an X-ray free-electron laser pulse. Taking advantage of the symmetry of the nanocrystal and the curvature of the Ewald sphere, we reconstruct the 3D structure of each nanocrystal from a single-shot diffraction pattern. By averaging a sufficient number of identical nanocrystals, this method may be used to determine the 3D structure of nanocrystals at atomic resolution. As symmetry exists in many virus particles, this method may also be applied to 3D structure studies of such particles at nanometer resolution on femtosecond time scales.
  • Akihiro Suzuki, Shin Furutaku, Kei Shimomura, Kazuto Yamauchi, Yoshiki Kohmura, Tetsuya Ishikawa, Yukio Takahashi
    PHYSICAL REVIEW LETTERS 112 (5) 053903-1 - 5 0031-9007 2014/02 [Refereed][Not invited]
    We report the first demonstration of hard x-ray ptychography using a multislice approach, which can solve the problem of the limited spatial resolution under the projection approximation. We measured ptychographic diffraction patterns of a two-layered object with a 105 mu m gap using 7 keV focused coherent x rays. We successfully reconstructed the phase map of each layer at similar to 50 nm resolution using a multislice approach, while the resolution was worse than similar to 192 nm under the projection approximation. The present method has the potential to enable the three-dimensional high-resolution observation of extended thick specimens in materials science and biology.
  • Y. Takahashi, A. Suzuki, S. Furutaku, K. Yamauchi, Y. Kohmura, T. Ishikawa
    Physical Review B Rapid Communications 87 121201-1 - 4 2013 [Refereed][Not invited]
  • Y. Takahashi, A. Suzuki, S. Furutaku, K. Yamauchi, Y. Kohmura, T. Ishikawa
    Applied Physics Letters 102 094102-1 - 4 2013 [Refereed][Not invited]
  • A. Suzuki, Y. Senba, H. Ohashi, Y. Kohmura, K. Yamauchi, T. Ishikawa, Y. Takahashi
    Journal of Physics: Conference Series 463 012039-1 - 4 2013 [Refereed][Not invited]
  • M. Nakasako, Y. Takayama, T. Oroguchi, Y. Sekiguchi, A. Kobayashi, K. Shirahama, M. Yamamoto, T. Hikima, K. Yonekura, S. Maki-Yonekura, Y. Kohmura, Y. Inubushi, Y. Takahashi, A. Suzuki, S. Matsunaga, Y. Inui, K. Tono, T. Kameshima, Y. Joti, T. Hoshi
    Review of Scientific Instruments 84 093705-1 - 11 2013 [Refereed][Not invited]
  • Y. Takahashi, A. Suzuki, N. Zettsu, T. Oroguchi, Y. Takayama, Y. Sekiguchi, A. Kobayashi, M. Yamamoto, M. Nakasako
    Nano Letters 13 6028 - 6032 2013 [Refereed][Not invited]
  • Yukio Takahashi, Akihiro Suzuki, Nobuyuki Zettsu, Yoshiki Kohmura, Kazuto Yamauchi, Tetsuya Ishikawa
    APPLIED PHYSICS LETTERS 99 (13) 131905-1 - 3 0003-6951 2011/09 [Refereed][Not invited]
    We propose an element mapping technique of nano-meso-microscale structures buried within large and/or thick objects by ptychographic x-ray diffraction microscopy using anomalous scattering. We performed quantitative imagings of both the electron density and Au element of Au/Ag nanoparticles at the pixel resolution of better than 10 nm in a field of view larger than 5 x 5 mu m(2) by directly phasing ptychographic coherent diffraction patterns acquired at two x-ray energies below the Au L-3 edge. This method provides us with multiscale structural and elemental information for understanding the element/property relationship linking nanoscale structures to macroscopic functional properties in material and biological systems. (C) 2011 American Institute of Physics. [doi:10.1063/1.3644396]
  • Yukio Takahashi, Akihiro Suzuki, Nobuyuki Zettsu, Yoshiki Kohmura, Yasunori Senba, Haruhiko Ohashi, Kazuto Yamauchi, Tetsuya Ishikawa
    PHYSICAL REVIEW B 83 (21) 214109-1 - 5 1098-0121 2011/06 [Refereed][Not invited]
    Ptychographic x-ray diffraction microscopy is a lensless imaging technique with a large field of view and high spatial resolution, which is also useful for characterizing the wavefront of an x-ray probe. The performance of this technique is degraded by positioning errors due to the drift between the sample and illumination optics. We propose an experimental approach for correcting the positioning errors and demonstrate success by two-dimensionally reconstructing both the wavefront of the focused x-ray beam and the complex transmissivity of the weakly scattering objects at the pixel resolution of better than 10 nm in the field of view larger than 5 mu m. This method is applicable to not only the observation of organelles inside cells or nano-mesoscale structures buried within bulk materials but also the characterization of probe for single-shot imaging with x-ray free electron lasers.

Conference Activities & Talks

  • Biological imaging: Short-and long-term requirements from users for hard X-ray beamlines  [Invited]
    Akihiro Suzuki
    SACLA Users' Meeting 2021  2021/03
  • SPring-8/SACLAを利用したコヒーレント回折イメージング  [Invited]
    第12回 日本放射光学会 若手研究会  2021/03
  • 回転体ミラーによる軟X線ナノビームを用いた磁区構造解析技術  [Invited]
    ISSP Workshop 2021  2021/03
  • Micro-liquid enclosure array for X-ray laser diffractive imaging of samples in solution  [Invited]
    Akihiro Suzuki
    A3 Foresight & 5 Star Alliance Joint Workshop on Organic/Inorganic Hybrid Nano Materials and Bio Imaging  2020/12
  • パルス状コヒーレントX線溶液散乱法の現状と高度化に向けた取り組み
    鈴木明大, 城地保昌, 別所義隆, 西野吉則
    第33回日本放射光学会年会・放射光科学合同シンポジウム  2020/01
  • 1粒子XFELイメージングのための超低バックグラウンド溶液試料セル開発に向けて  [Not invited]
    鈴木明大, 湯本博勝, 小山貴久, 城地保昌, 別所義隆, 登野健介, 矢橋牧名, 石川哲也, 大橋治彦, 西野吉則
    第33回日本放射光学会年会・放射光科学合同シンポジウム  2020/01
  • Feasibility study on solution sample holding technique for XFEL based single-particle imaging  [Not invited]
    Akihiro SUZUKI
    SACLA Users' Meeting 2019  2019/08
  • X線レーザー回折による溶液試料のナノ構造分析  [Invited]
    鈴木明大, 城地保昌, 別所義隆, 西野吉則
    日本放射光学会 第11回若手研究会  2019/08
  • X線レーザー回折による溶液中試料イメージング -高度化に向けた最新の取り組み-  [Invited]
    レーザー学会「レーザーバイオ医療」技術専門委員会  2019/07
  • Higher-Resolution XFEL-Based Coherent Diffractive Imaging with Multilayer Focusing Mirror System  [Not invited]
    Akihiro SUZUKI
    SACLA Users' Meeting 2018  2018/09
  • Recent Advances in XFEL-Based Coherent Diffractive Imaging at SACLA  [Invited]
    Akihiro Suzuki, Takashi Kimura, Yoshimasa Joti, Yoshitaka Bessho, Yoshinori Nishino
    Coherence 2018: International Workshop on Phase Retrieval and Coherent Scattering  2018/06
  • Imaging thermoresponsive gold nanoparticles in solution by X-ray laser diffraction  [Not invited]
    A. Suzuki, T. Kimura, R. Iida, H. Mitomo, Y. Joti, Y. Bessho, K. Niikura, K. Ijiro, Y. Nishino
    International Conference on X-ray Optics and Applications 2018  2018/04
  • X線レーザー回折による温度応答性金ナノ粒子の溶液中イメージング  [Not invited]
    鈴木明大, 木村隆志, 飯田良, 三友秀之, 城地保昌, 別所義隆, 新倉謙一, 居城邦治, 西野吉則
    第31回日本放射光学会・放射光科学合同シンポジウム  2018/01
  • 外部刺激応答性ナノ粒子のX線レーザーイメージング  [Invited]
    第14回X線結像光学シンポジウム  2017/11
  • X 線レーザー回折による温度応答性ナノ粒子の溶液中イメージング  [Invited]
    第五回アライアンス若手研究交流会​プログラム  2017/08
  • New design of environmental cells as a first step toward 3D imaging in solution by X-ray laser diffraction  [Not invited]
    Akihiro Suzuki, Tatsuro Tachibana, Naoya Tani, Yasumasa Joti, Yoshitaka Bessho, Takashi Kimura, Yoshinori Nishino
    International Conference on X-ray Optics and Applications 2017  2017/04
  • パルス状コヒーレントX線溶液散乱法による3次元イメージングに向けて  [Not invited]
    鈴木明大, 橘健朗, 谷直哉, 城地保昌, 別所義隆, 木村隆志, 西野吉則
    第30回日本放射光学会年会・放射光科学合同シンポジウム  2017/01


  • X線自由電子レーザーを用いた自動車用ナノマテリアルの無損傷イメージング
    西野 吉則, 鈴木 明大, 折笠 有基, 山重 寿夫  月刊OPTRONICS  4-  2020/03  [Not refereed][Invited]
  • 西野 吉則, 鈴木 明大, 木村 隆志, 城地 保昌, 別所 義隆  光学  47-  (10)  413  -417  2018/10  [Not refereed][Invited]
  • 西野 吉則, 木村 隆志, 鈴木 明大, 城地 保昌, 別所 義隆  レーザー研究  45-  (8)  2017/08  [Refereed][Invited]
  • SACLAを用いたコヒーレントイメージング
    西野 吉則, 木村 隆志, 鈴木 明大, 城地 保昌, 別所 義隆  日本結晶学会誌  59-  (1)  18  -23  2017/02  [Refereed][Invited]
  • 西野吉則, 木村隆志, 鈴木明大, 城地保昌, 大島泰郎, 別所義隆  バイオイメージング  25-  (2)  74  2016/08/22  [Not refereed][Not invited]
  • 鈴木明大, 高橋幸生  Isotope News  725-  12  -14  2014/09  [Not refereed][Invited]

Industrial Property Rights

Awards & Honors

  • 2016/01 日本放射光学会年会・放射光科学合同シンポジウム 学生発表賞
    受賞者: 鈴木明大
  • 2015/01 日本放射光学会年会・放射光科学合同シンポジウム 学生発表賞
    受賞者: 鈴木明大
  • 2014/01 日本放射光学会年会・放射光科学合同シンポジウム 学生発表賞
    受賞者: 鈴木明大
  • 2011/11 日本金属学会秋期講演大会 優秀ポスター賞
    受賞者: 鈴木明大

Research Grants & Projects

  • 大開口回転体ミラーとマルチスライス法による厚い試料の3次元軟X線イメージング
    Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists
    Date (from‐to) : 2020/04 -2022/03 
    Author : 鈴木 明大
  • 高感度動的結晶構造解析のための超低バックグラウンド試料セル
    Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    Date (from‐to) : 2020/04 -2022/03 
    Author : 鈴木 明大
  • X線レーザーとナノ構造形成技術を駆使した高速電子密度マッピング
    Date (from‐to) : 2017/04 -2020/03 
    Author : 鈴木明大
  • X 線ナノイメージング技術を応用したシングル ショット波面計測
    Date (from‐to) : 2016/04 -2017/03 
    Author : 鈴木明大
  • 走査型X線回折トモグラフィーによる3 次元ナノメ ートル空間分解バイオイメージング
    Date (from‐to) : 2013/04 -2016/03 
    Author : 鈴木明大

Educational Activities

Teaching Experience

  • Nanoimaging
    開講年度 : 2020
    課程区分 : 修士課程
    開講学部 : 情報科学研究科
    キーワード : ナノイメージング、X線計測、物質とX線との相互作用、X線源
  • Nanoimaging
    開講年度 : 2020
    課程区分 : 修士課程
    開講学部 : 情報科学院
    キーワード : ナノイメージング、X線計測、物質とX線との相互作用、X線源
  • Nanoimaging
    開講年度 : 2020
    課程区分 : 博士後期課程
    開講学部 : 情報科学研究科
    キーワード : ナノイメージング、X線計測、物質とX線との相互作用、X線源
  • Nanoimaging
    開講年度 : 2020
    課程区分 : 博士後期課程
    開講学部 : 情報科学院
    キーワード : ナノイメージング、X線計測、物質とX線との相互作用、X線源
  • Bioengineering and Bioinformatics Laboratory Ⅱ
    開講年度 : 2020
    課程区分 : 学士課程
    開講学部 : 工学部
    キーワード : 遺伝情報,生体電気現象,生体機能情報,生体計測,バイオエレクトロニクス
  • Bioengineering and Bioinformatics Laboratory Ⅰ
    開講年度 : 2020
    課程区分 : 学士課程
    開講学部 : 工学部
    キーワード : 遺伝情報,物理計測とセンサ,電気・電子計測,ディジタル技術,力学運動

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