研究者データベース

新坊 弦也(シンボウ ゲンヤ)
獣医学研究院 附属動物病院
特任助教

基本情報

所属

  • 獣医学研究院 附属動物病院

職名

  • 特任助教

学位

  • 博士(獣医学)

研究キーワード

  • 臨床獣医学   画像診断   

職歴

  • 2018年04月 - 現在 北海道大学 大学院獣医学研究院 特任助教

所属学協会

  • 日本獣医学会   日本獣医師会   日本獣医画像診断学会   

研究活動情報

論文

  • Michihito Tagawa, Genya Shimbo, Ken-Ichi Watanabe, Noriyuki Horiuchi, Yoshiyasu Kobayashi, Masaki Maezawa, Kotaro Matsumoto, Kazuro Miyahara
    The Journal of veterinary medical science 82 7 1000 - 1005 2020年07月31日 [査読有り][通常論文]
     
    A 12-year-old female domestic short-haired cat was presented due to weight loss, anorexia, and tachypnea. Complete blood count revealed severe anemia, leukocytosis with massive undifferentiated blast cells, and thrombocytopenia. Bone marrow aspiration showed acute myeloid leukemia, subclassified as monoblastic leukemia (M5a) based on the outcomes of the cytochemistry examinations. The SNAP feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) test using whole blood was negative. In addition, FeLV/FIV proviral polymerase chain reaction test using bone marrow aspirate was also negative. Although the cat was treated with doxorubicin, cytosine arabinoside, and prednisolone, anemia did not improve without blood transfusion. The owner declined further treatment after 2 months, and the cat died a few days later.
  • Michihito Tagawa, Genya Shimbo, Mizuki Tomihari, Masashi Yanagawa, Ken-Ichi Watanabe, Noriyuki Horiuchi, Yoshiyasu Kobayashi, Kazuro Miyahara
    The Journal of veterinary medical science 2020年05月18日 [査読有り][通常論文]
     
    A 1-year-old male mixed breed dog presented for the evaluation of progressive hindlimb paresis. Neurological examination indicated a spinal cord lesion between the 3rd thoracic and 3rd lumbar vertebrae. Magnetic resonance imaging (MRI) revealed an intramedullary spinal cord lesion located at the level of the 1st and 2nd lumbar vertebrae. Following cytoreductive surgery of the mass, palliative radiation therapy was administered. A diagnosis of nephroblastoma was made based on histological examination. After radiation therapy, the disappearance of the spinal lesion was confirmed by MRI. The dog was improved from gait abnormality and alive at 16 months postoperatively, with slight signs of neurological dysfunction.
  • Rommaneeya Leela-Arporn, Hiroshi Ohta, Genya Shimbo, Kiwamu Hanazono, Tatsuyuki Osuga, Keitaro Morishita, Noboru Sasaki, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 81 12 1697 - 1704 2019年12月18日 [査読有り][通常論文]
     
    Thus far, there are few computed tomography (CT) characteristics that can distinguish benign and malignant etiologies. The criteria are complex, subjective, and difficult to use in clinical applications due to the high level of experience needed. This study aimed to identify practical CT variables and their clinical relevance for broadly classifying histopathological diagnoses as benign or malignant. In this prospective study, all dogs with liver nodules or masses that underwent CT examination and subsequent histopathological diagnosis were included. Signalments, CT findings and histopathological diagnoses were recorded. Seventy liver nodules or masses in 57 dogs were diagnosed, comprising 18 benign and 52 malignant lesions. Twenty-three qualitative and quantitative CT variables were evaluated using univariate and stepwise multivariate analyses, respectively. Two variables, namely, the postcontrast enhancement pattern of the lesion in the delayed phase (heterogeneous; odds ratio (OR): 14.7, 95% confidence interval (CI): 0.82-262.03, P=0.0429) and the maximal transverse diameter of the lesion (>4.5 cm; OR: 33.3, 95% CI: 2.29-484.18, P=0.0006), were significantly related to the differentiation of benign from malignant liver lesions, with an area under the curve of 0.8910, representing an accuracy of 88.6%. These findings indicate that features from triple-phase CT can provide information for distinguishing pathological varieties of focal liver lesions and for clinical decision making. Evaluations of the maximal transverse diameter and postcontrast enhancement pattern of the lesion included simple CT features for predicting liver malignancy with high accuracy in clinical settings.
  • Michihito Tagawa, Genya Shimbo, Hisashi Inokuma, Kazuro Miyahara
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 31 6 836 - 843 2019年11月 [査読有り][通常論文]
     
    Circulating cell-free DNA (cfDNA) is extracellular DNA released into the bloodstream by apoptotic or necrotic tumor cells, with cfDNA determination proposed as a noninvasive, sensitive marker for the diagnosis of human cancer. We evaluated cfDNA quantification as a diagnostic and prognostic tool in dogs with various tumors. We quantified plasma cfDNA concentration by absolute real-time PCR of long interspersed nuclear elements in 50 dogs with malignant tumors, 13 dogs with benign tumors or nodules, and 11 healthy controls. Six patients with malignant tumors were followed-up, and plasma cfDNA was quantified throughout disease progression. We found that plasma cfDNA concentrations were significantly elevated in dogs with malignant tumors compared with dogs with benign nodules or healthy controls. The DNA integrity index (the ratio between long and short cfDNA fragments) was significantly lower in dogs with malignant tumors compared to healthy controls. Significantly higher cfDNA levels and a lower DNA integrity index were observed in dogs with lymphoma or leukemia, hemangiosarcoma, and distant metastasis; cfDNA levels correlated well with clinical stage and tended to increase during or before periods of disease progression, suggesting potential efficacy of cfDNA for the detection of distant metastasis and to monitor the clinical stage of neoplasia.
  • Masahiro Tamura, Hiroshi Ohta, Genya Shimbo, Tatsuyuki Osuga, Noboru Sasaki, Keitaro Morishita, Yumiko Kagawa, Mitsuyoshi Takiguchi
    Journal of veterinary internal medicine 33 5 2067 - 2074 2019年09月 [査読有り][通常論文]
     
    BACKGROUND: Two-dimensional shear wave elastography (2D-SWE) can noninvasively evaluate hepatic elastic modulus as shear wave velocity (SWV). Additionally, it may predict the presence of clinical relevant hepatic fibrosis (≥F2) in dogs with hepatic disease. OBJECTIVES: To investigate whether SWV measured by 2D-SWE can differentiate between dogs with (≥F2) and without (F0-1) clinically relevant hepatic fibrosis. ANIMALS: Twenty-eight client-owned dogs with hepatic disease and 8 normal healthy Beagle dogs were enrolled. METHODS: In this cross-sectional prospective study, SWVs were measured using 2D-SWE in all dogs. Hepatic fibrosis stages and necroinflammatory activity grades were histopathologically evaluated using a histological scoring scheme that was adapted from the Ishak schema used in human medicine. RESULTS: Median SWVs were significantly higher in dogs with clinically relevant hepatic fibrosis (2.04 m/s; range, 1.81-2.26 m/s) than in healthy dogs (1.51 m/s; range, 1.44-1.66 m/s; P = .007), and dogs without clinically relevant hepatic fibrosis (1.56 m/s; range, 1.37-1.67 m/s; P < .001). However, no significant difference was found in the SWVs between dogs without clinically relevant hepatic fibrosis and healthy dogs (P = .99). Furthermore, median SWVs were not significantly different among dogs with necroinflammatory activity, those without necroinflammatory activity, and healthy dogs (Kruskal-Wallis test, P = .12). CONCLUSIONS AND CLINICAL IMPORTANCE: The 2D-SWE may be useful for predicting the presence of hepatic fibrosis in dogs with hepatic disease.
  • Masahiro Tamura, Kensuke Nakamura, Tatsuyuki Osuga, Genya Shimbo, Noboru Sasaki, Keitaro Morishita, Hiroshi Ohta, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 81 8 1104 - 1108 2019年08月09日 [査読有り][通常論文]
     
    Contrast-enhanced ultrasonography (CEUS) is useful to distinguish benign and malignant focal liver lesions in dogs. Cholangiocellular adenoma is an extremely rare benign tumor in dogs and has not been examined using CEUS with Sonazoid. The aim of this study was to describe findings of CEUS with Sonazoid in three dogs with cholangiocellular adenoma. All three dogs showed contrast defects in the Kupffer phase and these findings mimicked malignant neoplasia during the Kupffer phase. Moreover, all dogs showed early washout and hypoechoic lesions relative to the surrounding normal liver parenchyma in the portal phase. To our knowledge, this is the first study to report that CEUS findings of cholangiocellular adenoma with Sonazoid mimicked malignancy in three dogs.
  • FeLV陰性であった急性単球性白血病の猫の2症例
    田川 道人, 新坊 弦也, 渡邉 謙一, 堀内 雅之, 古林 与志安, 宮原 和郎
    北海道獣医師会雑誌 63 8 338 - 338 (公社)北海道獣医師会 2019年08月 [査読有り][通常論文]
  • Genya Shimbo, Michihito Tagawa, Kotaro Matsumoto, Mizuki Tomihari, Masashi Yanagawa, Yuki Ueda, Hisashi Inokuma, Kazuro Miyahara
    The Journal of veterinary medical science 81 1 120 - 126 2019年01月25日 [査読有り][通常論文]
     
    This study proposed a novel radiographic positioning in order to image the cranioventral lung region using a portable X-ray unit and digital radiography system. In the novel position, calves were restrained in a chute and a unilateral forelimb was pulled cranially with the contralateral forelimb tied to the chute; the forelimbs were then spread cranio-caudally as in a scissor position (Three-legged view: TL view). In a preliminary study, we applied the TL view for imaging of 14 clinically healthy calves. In a clinical study, accuracy in detecting cranioventral lung lesions was compared between the standard standing view and the TL view for 19 calves, which were culled from herd; the results of postmortem examination were used as gold standard. Seven evaluators independently interpreted the images. The median (range) number of trials and the time for obtaining optimal position were 2 (1-7) and 263 sec (105-488), respectively in 14 healthy calves. Calves thicker than approximately 40 cm were not considered candidates for TL view in this setting because of difficulty in restraint and the low output of the portable X-ray unit. The TL view improved the detection of consolidation in the cranioventral lung region, compared with the standard view. The TL view was considered an optional view when the cranioventral lung region was an area of interest, because this view was relatively easy to perform and required a small number of personnel, even for large calves.
  • Shotaro Nakagun, Noriyuki Horiuchi, Kenichi Watanabe, Kotaro Matsumoto, Michihito Tagawa, Genya Shimbo, Yoshiyasu Kobayashi
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 30 5 779 - 783 2018年09月 [査読有り][通常論文]
     
    An 8-y 9-mo-old male Pug dog was presented because of anorexia, hindlimb ataxia, vomiting, and progressive weight loss. Clinical examinations revealed atrophic hindlimb muscles with decreased postural reaction, enlargement of the cardiac silhouette and megaesophagus on radiograph, and reduced cardiac contractility on ultrasonography. The dog died 10 d after the initial examination, and an autopsy was performed. Grossly, the heart was enlarged, with multifocal-to-coalescing extensive plaque-like areas of discoloration on the epicardial surface. On cross-section, the ventricles were moderately dilated, and discoloration extended into the myocardium. Peripheral lymph nodes were of normal size. Histologically, atypical lymphoid cells replaced the myocardium and also extensively infiltrated peripheral nerve bundles in various organs. With immunohistochemistry, the neoplastic cells exhibited strong immunoreactivity for CD3 and CD20, and were negative for CD8, granzyme B, CD79α, and Pax5. Double-label immunofluorescence confirmed co-expression of CD3 and CD20 by the neoplastic cells. Molecular clonality analysis presented a clonal T-cell receptor gamma gene rearrangement. The case was diagnosed as a CD3+/CD20+ peripheral T-cell lymphoma with prominent cardiac and peripheral nerve involvement, indicating neurolymphomatosis.
  • 脳梗塞を続発した脾梗塞の犬の1症例
    新坊弦也, 田川道人, 山本悠平, 宮原和郎
    日本獣医師会雑誌 71 8 443 - 448 (公社)日本獣医師会 2018年08月 [査読有り][通常論文]
     
    11歳8ヵ月、避妊雌のミニチュア・ダックスフントが血小板減少、多発性の脾臓腫瘤の精査のために来院した。症例は、来院前日に突然の左前後肢の麻痺、左眼の視覚障害を呈した。血液凝固系検査ではD-ダイマーの上昇が認められた。腹部超音波検査では脾臓に低エコー性を呈する血流を欠く楔型の病変が複数認められた。頭部MRI検査では、右側頭葉を中心とした脳梗塞と合致する所見が得られた。以上より、脾梗塞、脳梗塞と診断し、血栓予防療法を行った。その後の経過は良好であり、第118病日に治療終了とし、その後11ヵ月経過した現在も再発は認められていない。本症例は、過去に膵炎に類似した臨床症状を呈しており、また血栓傾向を引き起こす他の疾患は否定的であったことから、多発性の梗塞病変は膵炎に起因する凝固亢進状態に伴うものであったと考えられた。(著者抄録)
  • Shimbo G, Tagawa M, Yanagawa M, Miyahara K
    JFMS open reports 4 2 2055116918801602  2018年07月 [査読有り][通常論文]
  • Genya Shimbo, Michihito Tagawa, Kotaro Matsumoto, Mizuki Tomihari, Kazuro Miyahara
    Japanese Journal of Veterinary Research 66 2 105 - 112 2018年05月01日 [査読有り][通常論文]
     
    Thoracic radiography provides diagnostic assistance in assessing the severity of lung lesions in bovine respiratory diseases. We investigated the effects of a novel scatter correction processing software on the image quality of portable thoracic radiography in calves: this scatter correction method was recently developed for mobile bedside chest radiography in humans. Thoracic radiographs of the caudodorsal region were obtained from 30 calves of various sizes. Scatter correction processing of a grid ratio of 3: 1 or 8: 1 was applied to each image. The delineation of caudal thoracic vertebral bodies, scapulae, proximal third of the ribs, pulmonary vessels, and the aortic arch, as well as overall image quality were graded by five veterinarians using 5-point scales. Three types of images (original and scatter-corrected with grid ratios of 3: 1 and 8: 1) were compared using visual grading characteristics analysis. Scatter correction with a grid ratio of 3: 1 improved the overall image quality, at least for calves with a body thickness of ≤40 cm, and improved the delineation of some anatomical structures for larger calves. Scatter correction with a grid ratio of 8: 1 did not improve the delineation of any anatomical structures examined for calves > 40 cm in thickness or the overall image quality for calves > 30 cm in thickness. The present findings support the efficacy of scatter correction processing with a grid ratio of 3: 1 for portable thoracic radiography in calves.
  • Genya Shimbo, Michihito Tagawa, Kotaro Matsumoto, Mizuki Tomihari, Kazuro Miyahara
    Japanese Journal of Veterinary Research 66 1 13 - 19 2018年 [査読有り][通常論文]
     
    Thoracic radiography provides diagnostic assistance in assessing the severity of lung lesions in bovine respiratory diseases. We investigated the effects of grid use on overall image quality for portable thoracic radiography in calves. Thoracic radiographs of the dorsocaudal region were made for 30 calves of various sizes, using three acquisition techniques (digital radiography with no grid, with a 3: 1 grid, and with an 8: 1 grid). Overall image quality was graded independently by five veterinarians using a 5-point scale based on the visibility of the thoracic vertebral bodies, thoracic spinous processes, scapulae, proximal third of the ribs, caudal lobar pulmonary vessels, and aortic arch and on the level of image noise. The results were evaluated using Visual Grading Characteristics analysis. The 3: 1 grid significantly improved overall image quality, regardless of body size. The 8: 1 grid improved image quality only for calves smaller than 30 cm in thickness. The results of this study support the value of a 3: 1 grid for portable thoracic radiography in calves.
  • Michihito Tagawa, Chihiro Kurashima, Satoshi Takagi, Naoya Maekawa, Satoru Konnai, Genya Shimbo, Kotaro Matsumoto, Hisashi Inokuma, Keiko Kawamoto, Kazuro Miyahara
    PloS one 13 7 e0201222  2018年 [査読有り][通常論文]
     
    B cell high grade lymphoma is the most common hematopoietic malignancy in dogs. Although the immune checkpoint molecules, programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), and immune checkpoint inhibitors have been evaluated for the treatment of various human lymphoid malignancies, the expression of those molecules and their relationship with prognosis remain unknown in canine lymphoma. The objective of this study was to evaluate the expression of costimulatory molecules on peripheral blood lymphocytes and tumor infiltrating lymphocytes, in addition to associated ligand expression in the lymph nodes of patients with B cell multicentric high grade lymphoma. Eighteen patients diagnosed with B cell high grade lymphoma and nine healthy control dogs were enrolled. Flow cytometric analysis revealed that the expression of PD-1 on CD4+ peripheral and tumor infiltrating lymphocytes and CTLA-4 on CD4+ peripheral lymphocytes was significantly higher in the lymphoma group than in the control group. The expression level of CD80 mRNA was significantly lower in the lymphoma group than in the control group. In contrast, there were no significant differences in PD-L1, PD-L2, and CD86 expression between the groups. Dogs with CTLA-4 levels below the cutoff values, which were determined based on receiver operating characteristic curves, on peripheral CD4+, CD8+, and tumor infiltrating CD4+ lymphocytes had significantly longer survival than dogs with values above the cutoff. Although it is uncertain whether the expression of immune checkpoint molecules affect the biological behavior of canine lymphoma, one possible explanation is that PD-1 and CTLA-4 might be associated with the suppression of antitumor immunity in dogs with B cell high grade lymphoma, particularly through CD4+ T cells.
  • Genya Shimbo, Michihito Tagawa, Eiji Oohashi, Masashi Yanagawa, Kazuro Miyahara
    JOURNAL OF VETERINARY MEDICAL SCIENCE 79 10 1694 - 1697 2017年10月 [査読有り][通常論文]
     
    A 1-year-old neutered male Pekingese was presented for evaluation and further treatment of cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion was suspected following neurological examination. The dog showed signs of learning difficulty. Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex with a reduced number of gyri, as well as a cystic lesion associated with the quadrigeminal cistern. A diagnosis of lissencephaly, concurrent with a quadrigeminal cisternal cyst, was made. High-dose and multiple anticonvulsants were necessary to control the seizures. This is the first report of lissencephaly in a Pekingese.
  • Michihito Tagawa, Chihiro Kurashima, Genya Shimbo, Hiroshi Omura, Kenji Koyama, Noriyuki Horiuchi, Yoshiyasu Kobayashi, Keiko Kawamoto, Kazuro Miyahara
    JOURNAL OF VETERINARY MEDICAL SCIENCE 79 6 957 - 961 2017年06月 [査読有り][通常論文]
     
    A three-year-old spayed domestic short-haired cat presented for evaluation of weight loss, cardiomegaly and pleural effusion. Echocardiographic examination demonstrated a thickened pericardium with mild pericardial effusion and a large volume of pleural effusion characterized by exudate. Although the cat was treated with antibiotics, the clinical symptoms did not improve. The cat developed dyspnea and died on day 7. Necropsy revealed a large amount of modified transudates ascites, pleural effusion and markedly dilated pericardium. Histopathological examination revealed severe exudation of fibrin and granulation tissue in a thick layer of the epicardium. The cat was diagnosed with fibrinous pericarditis secondary to bacterial infection.
  • Michihito Tagawa, Yuhei Yamamoto, Genya Shimbo, Aiko Iguchi, Xuenan Xuan, Mizuki Tomihari, Kazuro Miyahara
    JOURNAL OF VETERINARY MEDICAL SCIENCE 79 5 871 - 875 2017年05月 [査読有り][通常論文]
     
    Cytotoxic T lymphocyte associated gene-4 (CTLA-4) is a costimulatory molecule, expressed on the surface of activated T cells that negatively regulates T cell activation. In humans, alternative splicing of the CTLA-4 gene generates two major isoforms of mRNA, and a soluble form of CTLA-4 (sCTLA-4) was detected in normal human serum. We describe alternatively spliced mRNA expressed in peripheral blood mononuclear cells obtained from a healthy dog lacking the transmembrane domain coded by exon 3 of the CTLA-4 gene. Immunoprecipitation and western blotting of dog serum revealed a band of approximately 23-kDa, which is consistent with the predicted size, based on the amino acid sequence of the canine sCTLA-4 obtained in this study.
  • Michihito Tagawa, Eiichi Kanai, Genya Shimbo, Mikiya Kano, Hideki Kayanuma
    JOURNAL OF VETERINARY MEDICAL SCIENCE 78 3 521 - 524 2016年03月 [査読有り][通常論文]
     
    Depth-width ratio (D/W) is the only quantitative item in the criteria recommended by the Japanese Ultrasound Society for the evaluation of breast tumors in humans. However, the usefulness of the D/W has not been evaluated in dogs. Eighty-six mammary masses in 34 female dogs underwent ultrasonographic examination to determine the D/W and other characteristics. Results of ultrasonographic and histopathologic examinations were compared. The D/W of malignant tumors was significantly greater than that of benign tumors, and it had a sensitivity of 56.3% and a specificity of 92.9% for the diagnosis of malignancy when the threshold of D/W was 0.7. In addition, irregular margin, polymorphous shape and heterogeneous internal echographic characteristics were correlated with malignancy.
  • ラット脳腫瘍における間欠的低酸素の可視化と放射線感受性に与える影響
    安井博宣, 新坊弦也, 山盛徹, 永根大幹, 趙松吉, 久下祐司, 稲波修
    日本獣医学会学術集会講演要旨集 152nd 316  2011年 [査読無し][通常論文]

講演・口頭発表等

  • 胸部X線読影  [招待講演]
    新坊弦也
    第16回 日本獣医内科学アカデミー 2020年02月 公開講演,セミナー,チュートリアル,講習,講義等
  • 胸部レントゲン撮影!撮影技術から読影まで  [招待講演]
    第40回動物臨床医学会記念年次大会 2019年11月 公開講演,セミナー,チュートリアル,講習,講義等
  • 腹部・胸部レントゲン〜撮影と読影の基礎〜  [招待講演]
    新坊 弦也
    第15回獣医内科学アカデミー学術大会 2019年02月
  • 結果の出せる画像診断法  [招待講演]
    新坊弦也
    北海道獣医師会十勝支部主催小動物関連講習会 2016年11月 公開講演,セミナー,チュートリアル,講習,講義等

その他活動・業績

  • 肺病変を形成した猫骨髄腫関連疾患の1症例
    田川 道人, 上田 裕貴, 新坊 弦也, 松本 高太郎, 宮原 和郎 北海道獣医師会雑誌 64 (3) 1 -4 2020年03月 [査読無し][通常論文]
     
    8歳11ヵ月齢の雑種猫、避任雌が食欲不振と呼吸困難を主訴に近医を受診した。胸部レントゲン検査にて肺野の不透過性亢進を認め、精査を希望して帯広畜産大学動物医療センターに紹介された。胸部レントゲン検査にて肺前葉および中葉は無気肺化し、内部に気管支陰影が観察され、後葉にも綿毛状の不透過性亢進領域を認めた。超音波検査にて浸潤性肺病変が疑われ、無気肺化した肺の細針吸引細胞診所見およびモノクローナルガンモパシーの存在から骨髄腫関連疾患と診断した。症例はL-アスパラギナーゼとプレドニゾロンによる治療に良好に反応したが、治療開始後6ヵ月で腎臓に再発を認め斃死した。(著者抄録)
  • 本態性高ナトリウム血症を伴った分葉型全前脳胞症の猫の1症例
    新坊 弦也, 田川 道人, 柳川 将志, 宮原 和郎 日本獣医師会雑誌 72 (4) 233 -234 2019年04月 [査読無し][通常論文]
  • 田川 道人, 新坊 弦也, 柳川 将志, 岡田 一喜, 宮原 和郎 北海道獣医師会雑誌 62 (11) 467 -470 2018年11月 [査読無し][通常論文]
     
    4歳11ヵ月齢の雑種猫、去勢雄が食欲不振と呼吸困難を主訴に近医を受診した。対症療法を行うも改善せず、精査を希望して帯広畜産大学動物医療センターを紹介受診した。いびき様呼吸音(stertor)、頭部X線検査から鼻腔および鼻咽頭領域の疾患を疑い、頭部CT検査および組織生検により鼻咽頭道に発生したリンパ腫と診断した。症例は抗がん剤治療に良好に反応し、治療終了後2年経った現在まで臨床症状の再発は認められていない。(著者抄録)
  • 鼻咽頭道に発生したリンパ腫の猫の1症例
    田川道人, 新坊弦也, 柳川将志, 岡田一喜, 宮原和郎 北海道獣医師会雑誌 62 (11) 467 -470 2018年11月 [査読無し][通常論文]
     
    4歳11ヵ月齢の雑種猫、去勢雄が食欲不振と呼吸困難を主訴に近医を受診した。対症療法を行うも改善せず、精査を希望して帯広畜産大学動物医療センターを紹介受診した。いびき様呼吸音(stertor)、頭部X線検査から鼻腔および鼻咽頭領域の疾患を疑い、頭部CT検査および組織生検により鼻咽頭道に発生したリンパ腫と診断した。症例は抗がん剤治療に良好に反応し、治療終了後2年経った現在まで臨床症状の再発は認められていない。(著者抄録)
  • 竹内恭介, 金尚昊, 大田寛, 華園究, 新坊弦也, 石塚友人, 細谷謙次, 奥村正裕 北海道獣医師会雑誌 62 (8) 343 2018年08月24日 [査読無し][通常論文]
  • 田川道人, 新坊弦也, 新坊弦也, 富張瑞樹, 大石明広, 松本高太郎, 猪熊壽, 宮原和郎 日本獣医学会学術集会講演要旨集 161st 431 2018年08月21日 [査読無し][通常論文]
  • 中川 肇, 田川 道人, 新坊 弦也, 富張 瑞樹, 柳川 将志, 互野 佑香, 渡邉 謙一, 堀内 雅之, 古林 与志安, 宮原 和郎 北海道獣医師会雑誌 62 (8) 339 -339 2018年08月 [査読無し][通常論文]
  • 田川 道人, 新坊 弦也, 大村 寛, 柳川 将志, 田中 佑典, 渡邉 謙一, 堀内 雅之, 古林 与志安, 宮原 和郎 北海道獣医師会雑誌 62 (8) 333 -333 2018年08月 [査読無し][通常論文]
  • 新坊 弦也, 田川 道人, 柳川 将志, 宮原 和郎 北海道獣医師会雑誌 62 (8) 342 -342 2018年08月 [査読無し][通常論文]
  • 無症候性両側腎盂尿管移行部狭窄の猫の1例
    田川 道人, 新坊 弦也, 柳川 将志, 宮原 和郎 日本獣医麻酔外科学雑誌 49 (Suppl.1) 321 -321 2018年06月 [査読無し][通常論文]
  • 田川 道人, 新坊 弦也, 富張 瑞樹, 柳川 将志, 宮原 和郎 北海道獣医師会雑誌 62 (3) 73 -76 2018年03月 [査読無し][通常論文]
     
    15歳4ヵ月齢の雑種猫、避妊雌が皮膚腫瘤を主訴に近医を受診し、切除手術を受けアポクリン導管癌と診断された。しかし早期に再発を認めたため、帯広畜産大学動物医療センターを紹介受診した。CT検査にて皮下への広範囲の浸潤が確認され、前進皮弁を用いた拡大切除と術後の放射線治療を行った。術後は一時閉眼障害がみられたが大きな問題となることはなく、術後7ヵ月で慢性腎臓病にて斃死するまで明らかな再発、転移は認められなかった。(著者抄録)
  • 新坊 弦也, 猪狩 皓介, 三好 雅史, 田川 道人, 宮原 和郎 日本獣医師会雑誌 71 (1) 31 -35 2018年 [査読有り][通常論文]
  • 田川 道人, 倉島 千尋, 山本 悠平, 新坊 弦也, 柳川 将志, 小山 憲司, 堀内 雅之, 古林 与志安, 宮原 和郎 獣医畜産新報 70 (10) 763 -767 2017年10月 [査読有り][通常論文]
     
    12歳8ヵ月齢のミニチュア・ダックスフンド、避妊雌が口腔内腫瘤を主訴に帯広畜産大学動物医療センターを受診した。左下顎の第四前臼歯から第一後臼歯内側の歯肉より発生する黒色腫瘤を認め、一部を組織生検した結果、悪性黒色腫と診断された。そこで口腔内腫瘤および同側下顎リンパ節の外科的切除を行ったが、原発部位の切除縁において腫瘍巣が観察された。その後、補助療法として低分割放射線照射(1回8.0Gy×4回、1週間毎)およびピロキシカムの投与を行った。症例には、照射部位の口内炎、脱毛が認められたものの、術後1年まで再発転移はなく、1年8ヵ月後に他疾患にて死亡した。補助療法が有効であった可能性や、本腫瘍自体が良性の挙動を取った可能性が考えられた。(著者抄録)
  • 新坊弦也, 田川道人, 中川肇, 宮原和郎 日本獣医学会学術集会講演要旨集 160th 450 2017年08月30日 [査読無し][通常論文]
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  • バルーン拡張カテーテルにより緩和的尿路確保を行った前立腺癌の犬の1症例
    田川 道人, 倉島 千尋, 山本 悠平, 新坊 弦也, 元尾 空志, 宮原 和郎 北海道獣医師会雑誌 61 (2) 36 -40 2017年02月 [査読無し][通常論文]
     
    11歳7ヵ月齢のミニチュア・ダックスフンド、去勢オスが血尿を主訴に近医を受診した。対症療法が実施されたものの、排便痛と前立腺腫大が認められ、帯広畜産大学動物医療センターを紹介受診した。X線検査および超音波検査にて前立腺および内腸骨リンパ節を含む複数のリンパ節の腫大が確認され、前立腺尿道部の細胞診にて臨床的に前立腺癌と診断された。ミトキサントロン、ピロキシカム、リン酸トセラニブ等による内科治療を行ったが反応に乏しく、腫瘍浸潤による尿路閉塞が認められた。食道用バルーン拡張カテーテルを用いて緩和的バルーン拡張術を実施し、26日間自力排尿が可能となった。その後急速に転移が進行し、本学受診後第174病日に自宅にて斃死した。(著者抄録)
  • 山本悠平, 田川道人, 新坊弦也, 井口愛子, 玄学南, 富張瑞樹, 宮原和郎 日本獣医学会学術集会講演要旨集 159th 463 2016年08月30日 [査読無し][通常論文]
  • 倉島 千尋, 田川 道人, 高木 哲, 前川 直也, 今内 覚, 新坊 弦也, 富張 瑞樹, 松本 高太郎, 猪熊 壽, 川本 恵子, 宮原 和郎 日本獣医学会学術集会講演要旨集 159回 462 -462 2016年08月 [査読無し][通常論文]
  • 上田 裕貴, 薦岡 勇気, 中島 永実, 新保 sumire, 佐々木 基樹, 柳川 将志, 新坊 弦也, 田川 道人, 大村 寛, 富張 瑞樹, 宮原 和郎, 秋吉 秀保, 大石 明広 日本獣医学会学術集会講演要旨集 159回 447 -447 2016年08月 [査読無し][通常論文]
  • 新坊弦也, 宮林孝仁, 佐藤賢明, 石川温士 日本産業動物獣医学会(九州)・日本小動物獣医学会(九州)・日本獣医公衆衛生学会(九州) 2013 108 2013年 [査読無し][通常論文]

受賞

  • 2018年09月 北海道獣医師会 北海道地区学会長賞
     
    受賞者: 新坊 弦也
  • 2017年10月 十勝獣医師会 獣医学術奨励賞
     
    受賞者: 新坊 弦也

共同研究・競争的資金等の研究課題

  • 人工知能による伴侶動物のX線像におけるBone Suppression処理の開発
    日本学術振興会:科学研究費助成事業 若手研究
    研究期間 : 2020年04月 -2022年03月 
    代表者 : 新坊 弦也

大学運営

委員歴

  • 2018年06月 - 現在   日本獣医画像診断学会   検定委員

社会貢献活動

  • 下部呼吸器疾患のX線診断
    期間 : 2018年11月21日
    役割 : 講師
    主催者・発行元 : 北海道大学動物医療センター
    イベント・番組・新聞雑誌名 : 卒後教育セミナー


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