研究者データベース

澁川 敦史(シブカワ アツシ)
電子科学研究所 生命科学研究部門
准教授

基本情報

所属

  • 電子科学研究所 生命科学研究部門

職名

  • 准教授

学位

  • 博士(情報科学)(2014年03月 北海道大学)

J-Global ID

研究キーワード

  • ホログラフィ,光波面制御,光遺伝学,ロドプシン   

研究分野

  • ものづくり技術(機械・電気電子・化学工学) / 電子デバイス、電子機器

研究活動情報

論文

  • Masuzu Kikuchi, Keiichi Kojima, Shin Nakao, Susumu Yoshizawa, Shiho Kawanishi, Atsushi Shibukawa, Takashi Kikukawa, Yuki Sudo
    Scientific reports 11 1 14765 - 14765 2021年07月20日 [査読有り]
     
    Microbial rhodopsins are photoswitchable seven-transmembrane proteins that are widely distributed in three domains of life, archaea, bacteria and eukarya. Rhodopsins allow the transport of protons outwardly across the membrane and are indispensable for light-energy conversion in microorganisms. Archaeal and bacterial proton pump rhodopsins have been characterized using an Escherichia coli expression system because that enables the rapid production of large amounts of recombinant proteins, whereas no success has been reported for eukaryotic rhodopsins. Here, we report a phylogenetically distinct eukaryotic rhodopsin from the dinoflagellate Oxyrrhis marina (O. marina rhodopsin-2, OmR2) that can be expressed in E. coli cells. E. coli cells harboring the OmR2 gene showed an outward proton-pumping activity, indicating its functional expression. Spectroscopic characterization of the purified OmR2 protein revealed several features as follows: (1) an absorption maximum at 533 nm with all-trans retinal chromophore, (2) the possession of the deprotonated counterion (pKa = 3.0) of the protonated Schiff base and (3) a rapid photocycle through several distinct photointermediates. Those features are similar to those of known eukaryotic proton pump rhodopsins. Our successful characterization of OmR2 expressed in E. coli cells could build a basis for understanding and utilizing eukaryotic rhodopsins.
  • Keiichi Kojima, Natsuki Miyoshi, Atsushi Shibukawa, Srikanta Chowdhury, Masaki Tsujimura, Tomoyasu Noji, Hiroshi Ishikita, Akihiro Yamanaka, Yuki Sudo
    The Journal of Physical Chemistry Letters 11 15 6214 - 6218 2020年07月22日 [査読有り]
     
    Anion channelrhodopsin-2 (GtACR2) was identified from the alga Guillardia theta as a light-gated anion channel, providing a powerful neural silencing tool for optogenetics. To expand its molecular properties, we produced here GtACR2 variants by strategic mutations on the four residues around the retinal chromophore (i.e., R129, G152, P204, and C233). After the screening with the Escherichia coli expression system, we estimated spectral sensitivities and the anion channeling function by using the HEK293 expression system. Among the mutants, triple (R129M/G152S/C233A) and quadruple (R129M/G152S/P204T/C233A) mutants showed the significantly red-shifted absorption maxima (λmax = 498 and 514 nm, respectively) and the long-lived channel-conducting states (the half-life times were 3.4 and 5.4 s, respectively). In addition, both mutants can be activated and inactivated by different wavelengths, representing their step-functional ability. We nicknamed the quadruple mutant "GLaS-ACR2" from its green-sensitive, long-lived, step-functional properties. The unique characteristics of GLaS-ACR2 suggest its high potential as a neural silencing tool.
  • The Unlimited Potential of Microbial Rhodopsins as Optical Tools
    K. Kojima, A. Shibukawa, Y. Sudo
    Biochemistry 59 3 218 - 229 2019年12月 [査読有り][招待有り]
  • Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination
    T. Yamanashi, M. Maki, K. Kojima, A. Shibukawa, T. Tsukamoto, S. Chowdhury, A. Yamanaka, S. Takagi, Y. Sudo
    Scientific Reports 9 7863 2019年05月 [査読有り][通常論文]
  • Photochemical Characterization of a New Heliorhodopsin from the Gram-Negative Eubacterium Bellilinea caldifistulae (BcHeR) and Comparison with Heliorhodopsin-48C12
    A. Shibukawa, K. Kojima, Y. Nakajima, Y. Nishimura, S. Yoshizawa, Y. Sudo
    Biochemistry 58 26 2934 - 2943 2019年05月 [査読有り][通常論文]
  • Virtual phase conjugation based optical tomography for single-shot three-dimensional imaging
    Yuta Goto, Atsushi Okamoto, Atsushi Shibukawa, Kazuhisa Ogawa, Akihisa Tomita
    Optics Express 26 3779 - 3790 2018年02月 [査読有り][通常論文]
  • Mooseok Jang†, Yu Horie†, Atsushi Shibukawa†, Joshua Brake, Yan Liu, Seyedeh Mahsa Kamali, Amir Arbabi, HaowenRuan, Andrei Faraon, Changhuei Yang
    Nature Photonics 12 84 - 90 2018年02月 [査読有り][通常論文]
  • Edward Haojiang Zhou, Atsushi Shibukawa, Joshua Brake, Haowen Ruan, Changhuei Yang
    OPTICA 3 10 1107 - 1113 2016年10月 [査読有り][通常論文]
     
    Imaging of a weak target hidden behind a scattering medium can be significantly confounded by glare. We report a method, termed coherence gated negation (CGN), that uses destructive optical interference to suppress glare and allow improved imaging of a weak target. As a demonstration, we show that by permuting through a set range of amplitude and phase values for a reference beam interfering with the optical field from the glare and target reflection, we can suppress glare by an order of magnitude, even when the optical wavefront is highly disordered. This strategy significantly departs from conventional coherence gating methods in that CGN actively "gates out" the unwanted optical contributions while conventional methods "gate in" the target optical signal. We further show that the CGN method can outperform conventional coherence gating image quality in certain scenarios by more effectively rejecting unwanted optical contributions. (C) 2016 Optical Society of America
  • Nicolino Stasio†, Atsushi Shibukawa†, Ioannis N, Papadopoulos, Salma Farahi, Olivier Simandoux, Jean-Pierre Huignard, Emmanuel Bossy, Christophe Moser, Demetri Psaltis
    BIOMEDICAL OPTICS EXPRESS 6 12 4619 - 4631 2015年12月 [査読有り][通常論文]
     
    In this paper we demonstrate the enhancement of the sensing capabilities of glass capillaries. We exploit their properties as optical and acoustic waveguides to transform them potentially into high resolution minimally invasive endoscopic devices. We show two possible applications of silica capillary waveguides demonstrating fluorescence and optical-resolution photoacoustic imaging using a single 330 mu m-thick silica capillary. A nanosecond pulsed laser is focused and scanned in front of a capillary by digital phase conjugation through the silica annular ring of the capillary, used as an optical waveguide. We demonstrate optical-resolution photoacoustic images of a 30 mu m-thick nylon thread using the water-filled core of the same capillary as an acoustic waveguide, resulting in a fully passive endoscopic device. Moreover, fluorescence images of 1.5 mu m beads are obtained collecting the fluorescence signal through the optical waveguide. This kind of silica-capillary waveguide together with wavefront shaping techniques such as digital phase conjugation, paves the way to minimally invasive multi-modal endoscopy. (C) 2015 Optical Society of America
  • Yuta Goto, Atsushi Okamoto, Atsushi Shibukawa, Akihisa Tomita, Masanori Takabayashi
    2015 20th Microoptics Conference (MOC) 2015年10月
  • Jin Nozawa, Atsushi Okamoto, Atsushi Shibukawa, Masanori Takabayashi, Akihisa Tomita
    APPLIED OPTICS 54 29 8644 - 8652 2015年10月 [査読有り][通常論文]
     
    We propose a two-channel holographic diversity interferometer (2ch-HDI) system for single-shot and highly accurate measurements of complex amplitude fields with a simple optical setup. In this method, two phase-shifted interference patterns are generated, without requiring a phase-shifting device, by entering a circularly polarized reference beam into a polarizing beam splitter, and the resulting patterns are captured simultaneously using two image sensors. However, differences in the intensity distributions of the two image sensors may lead to serious measurement errors. Thus, we also develop a two-channel algorithm optimized for the 2ch-HDI to compensate for these differences. Simulation results show that this algorithm can compensate for such differences in the intensity distributions in the two image sensors. Experimental results confirm that the combination of the 2ch-HDI and the calculation algorithm significantly enhances measurement accuracy. (c) 2015 Optical Society of America
  • Kaori Nishimaki, Atsushi Okamoto, Atsushi Shibukawa, Akihisa Tomita, Yoshihisa Takayama, Masatoshi Bunsen
    JAPANESE JOURNAL OF APPLIED PHYSICS 53 8 08MB13  2014年07月 [査読有り][通常論文]
     
    In optical intersatellite communication, the background light consisting mainly of sunlight decrease transmission rate with increasing bit error. A spatial filtering system using a double-phase-conjugate mirror (DPCM) and a phase plate is proposed to block the background light, which cannot be filtered out by using wavelength filters, polarization filters, or dousers. In this system, the effect of wavefront distortion caused by the phase plate and the compensation effect of the distortion by phase conjugate light from the DPCM are effectively combined for spatially separating signal light and background light. We demonstrated the reduction of the background light by the proposed system and optimized the phase plate for maximizing this reduction effect. As a result, it was clarified that the transmission rate can be drastically improved up to 11-fold. (C) 2014 The Japan Society of Applied Physics
  • Kaori Nishimaki, Atsushi Okamoto, Atsushi Shibukawa, Masanori Takabayashi, Akihisa Tomita, Yoshihisa Takayama
    OPTICAL REVIEW 21 3 415 - 424 2014年05月 [査読有り][通常論文]
     
    A double phase conjugate mirror (DPCM), created by two mutually incoherent beams entering photorefractive nonlinear materials, can generate a phase conjugate beam whose reflectivity may be greater than 100%. Even though the conditions of the incident beams are changed, the DPCM can be dynamically reconfigured by using a Sn2P2S6 crystal with a high response speed. These features of the DPCM are advantageous, particularly in an optical inter-satellite communication system. In particular, use of the phase conjugate beam from the DPCM offers wavefront compensation and amplification in satellite communication. In addition, the dynamically reconfigurable DPCM using a Sn2P2S6 crystal relaxes the acquisition accuracy of the signal beam in the system. In this study, the temporal and spatial operating characteristics of the DPCM using a Sn2P2S6 crystal were first clarified. Next, an inter-satellite system based on the DPCM was proposed, and it was demonstrated that our system significantly improves the tolerance of the acquisition accuracy and tracking time. (C) 2014 The Japan Society of Applied Physics
  • Atsushi Shibukawa, Atsushi Okamoto, Yuta Goto, Satoshi Honma, Akihisa Tomita
    OPTICS EXPRESS 22 10 11918 - 11929 2014年05月 [査読有り][通常論文]
     
    In a conventional digital phase conjugation system, only the phase of an input light is time-reversed. This deteriorates phase conjugation fidelity and restricts application fields to specific cases only when the input light has uniformly-distributed scattered wavefront. To overcome these difficulties, we present a digital phase conjugate mirror based on parallel alignment of two phase-only spatial light modulators (SLMs), in which both amplitude and phase of the input light can be time-reversed. Experimental result showed that, in the phase conjugation through a holographic diffuser with diffusion angle of 0.5 degree, background noises decrease to 65% by our digital phase conjugation mirror. (C)2014 Optical Society of America
  • 光複素振幅制御技術を用いた超高密度ホログラフィックメモリに関する研究
    渋川敦史
    北海道大学 2014年03月 [査読有り][招待有り]
  • Atsushi Shibukawa, Atsushi Okamoto, Masanori Takabayashi, Akihisa Tomita
    OPTICS EXPRESS 22 4 3968 - 3982 2014年02月 [査読有り][通常論文]
     
    We propose a spatial cross modulation method using a random diffuser and a phase-only spatial light modulator (SLM), by which arbitrary complex-amplitude fields can be generated with higher spatial resolution and diffraction efficiency than off-axis and double-phase computer-generated holograms. Our method encodes the original complex object as a phase-only diffusion image by scattering the complex object using a random diffuser. In addition, all incoming light to the SLM is consumed for a single diffraction order, making a diffraction efficiency of more than 90% possible. This method can be applied for holographic data storage, three-dimensional displays, and other such applications. (C) 2014 Optical Society of America
  • Keisuke Zukeran, Atsushi Okamoto, Masanori Takabayashi, Atsushi Shibukawa, Kunihiro Sato, Akihisa Tomita
    JAPANESE JOURNAL OF APPLIED PHYSICS 52 9 09LD13  2013年09月 [査読有り][通常論文]
     
    We proposed a double-referential holography (DRH) that allows phase-detection without external additional beams. In the DRH, phantom beams, prepared in the same optical path as signal beams and preliminary multiplexed in a recording medium along with the signal, are used to produce interference fringes on an imager for converting a phase into an intensity distribution. The DRH enables stable and high-accuracy phase detection independent of the fluctuations and vibrations of the optical system owing to medium shift and temperature variation. Besides, the collinear arrangement of the signal and phantom beams leads to the compactness of the optical data storage system. We conducted an experiment using binary phase modulation signals for verifying the DRH operation. In addition, 38-level spatial quadrature amplitude modulation signals were successfully reproduced with the DRH by numerical simulation. Furthermore, we verified that the distributed phase-shifting method moderates the dynamic range consumption for the exposure of phantom beams. (c) 2013 The Japan Society of Applied Physics
  • Atsushi Shibukawa, Atsushi Okamoto, Yuta Wakayama, Akihisa Tomita, Hisatoshi Funakoshi, Kunihiro Sato
    JAPANESE JOURNAL OF APPLIED PHYSICS 52 9 09LD03  2013年09月 [査読有り][通常論文]
     
    To suppress interpage crosstalk that strongly restricts holographic data storage capacity, a digital image diffusion technique was proposed. In this technique, signal and crosstalk components are separated from the propagation angle difference produced by using a random diffuser and the nature of phase conjugate lights. The most attractive feature of the technique is that crosstalk suppression can be conducted while mostly keeping the conventional holographic data storage system unchanged by integrating optical processing and digital processing effectively. The connection between the two types of processing is realized by using two spatial light modulators for complex amplitude generation and phase detection methods for complex amplitude measurement. The simulation results showed that the proposed technique could increase the recording density 5.5-fold and reduce the shift pitch by a factor of 5 in comparison with conventional multiplexing methods when the diffusion angle of the diffuser is 10 degrees. (c) 2013 The Japan Society of Applied Physics
  • 多層化コリニアホログラムによる超高密度記録
    岡本淳, 渋川敦史
    光学 40 11 591 - 593 2011年11月 [査読無し][招待有り]
  • Atsushi Shibukawa, Atsushi Okamoto, Akihisa Tomita, Masanori Takabayashi, Kunihiro Sato
    JAPANESE JOURNAL OF APPLIED PHYSICS 50 9 09ME10  2011年09月 [査読有り][通常論文]
     
    We proposed a new multilayer collinear holographic memory (MCHM) with a movable random phase mask that can act as an interlayer crosstalk reducer. First, to clarify the feasibility of our proposed device, we showed that it has an extremely sharp shift selectivity along the thickness direction of medium of nearly 5.0 mu m when the numerical aperture of the objective lens is 0.60. Next, we demonstrated that the utilization of the movable random phase mask can suppress interlayer crosstalk sufficiently, resulting in the improvement in the quality of reconstructed signals. Moreover, we revealed that the MCHM, in which the parallel use of a multilayered technique and collinear shift multiplexing is performed, brings out the medium potential sufficiently in terms of signal to noise ratio and medium dynamic range consumption. Finally, we verified that the MCHM can achieve a nearly 2 times larger data density at least compared with a conventional collinear holographic memory. (C) 2011 The Japan Society of Applied Physics

講演・口頭発表等

  • Megahertz Wavefront Control through Scattering Media  [通常講演]
    Atsushi Shibukawa, Hideharu Mikami, Mooseok Jang, Yuki Sudo
    The 22nd RIES-Hokudai International Symposium 2021年12月 ポスター発表
  • コンプレックス波面整形による光散乱との共生  [招待講演]
    渋川敦史
    コニカミノルタカレッジ「先端光学」 2021年12月 公開講演,セミナー,チュートリアル,講習,講義等
  • Ultrafast wavefront control involving scattering media  [招待講演]
    Atsushi Shibukawa, Jang Mooseok, Hideharu Mikami, Yuki Sudo
    International Symposium on Imaging, Sensing, and Optical Memory 2021 2021年10月 口頭発表(招待・特別)
  • LED光源を用いたアーキロドプシン3由来の膜電位感受性蛍光の観察  [通常講演]
    川西志歩, 小島慧一, 渋川敦史, 坂本雅行, 須藤雄気
    第12回日本生物物理学会 中国四国支部大会 2021年05月 ポスター発表

その他活動・業績

  • 菅 悠太, 岡本 淳, 渋川 敦史, 舟越 久敏, 佐久間 大樹, 富田 章久 電子情報通信学会ソサイエティ大会講演論文集 2015 (1) 108 -108 2015年08月25日
  • 後藤 優太, 岡本 淳, 渋川 敦史 電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 114 (460) 9 -14 2015年02月23日
  • 後藤 優太, 岡本 淳, 渋川 敦史 電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 114 (459) 9 -14 2015年02月23日
  • NISHIMAKI Kaori, OKAMOTO Atsushi, SHIBUKAWA Atsushi, TOMITA Akihisa, TAKAYAMA Yoshihisa 電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 114 (124) 87 -92 2014年07月09日 
    We propose an optical satellite communication system which can dynamically compensate the signal beam wavefront using phase conjugation technique. The proposed system converts the signal beam wavefront into the phase conjugate wavefront using the double phase conjugate mirror formed by the photorefractive materials and communication beams. By using the time reversal wave and wavefront compensation effect produced by the phase conjugate wavefront, the automatic tracking of satellites and the background light reduction can be achieved at the same time. In addition, we consider the application of proposed method for the visible light communication on the ground.
  • NISHIMAKI Kaori, OKAMOTO Atsushi, SHIBUKAWA Atsushi, TOMITA Akihisa, TAKAYAMA Yoshihisa 電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 114 (125) 87 -92 2014年07月09日 
    We propose an optical satellite communication system which can dynamically compensate the signal beam wavefront using phase conjugation technique. The proposed system converts the signal beam wavefront into the phase conjugate wavefront using the double phase conjugate mirror formed by the photorefractive materials and communication beams. By using the time reversal wave and wavefront compensation effect produced by the phase conjugate wavefront, the automatic tracking of satellites and the background light reduction can be achieved at the same time. In addition, we consider the application of proposed method for the visible light communication on the ground.
  • 瑞慶覽 圭佑, 岡本 淳, 高林 正典, 渋川 敦史, 富田 章久 映像情報メディア学会技術報告 37 (10) 1 -7 2013年02月15日 
    再生時に干渉用の光波を生成・照射する機構を必要とせずに,参照光の照射のみで位相変調信号を復調できる新たなホログラフィックメモリとして2重参照型ホログラフィックメモリ(DRHM)を提案する.本技術では小型かつ正確な再生光の複素振幅検出によって,多値数の大きな位相変調信号や空間直交振幅変調(SQAM)信号の使用が可能になり,ホログラフィックメモリの大幅な高密度化,高速化が期待できる.本論文では,DRHMの基本原理を示すと共に,同技術による38値SQAM信号の記録再生シミュレーションを行う.さらに,DRHMの再生品質を高めることができる手法を新たに提案し,DRHMの再生エラーが大幅に低減されることを示す.

特許

  • 特願2021-153788:光変調装置及び集光装置  2021年09月22日
    渋川 敦史, 須藤 雄気, ムサク ジャング  渋川 敦史(北海道大学), 須藤 雄気(岡山大学), ムサク ジャング(韓国科学技術院)
  • 特開WO/2018/195309:HIGHLY SCATTERING METASURFACE PHASE MASKS FOR COMPLEX WAVEFRONT ENGINEERING  2018年10月25日
    JANG, Mooseok, US HORIE, Yu, US SHIBUKAWA, Atsushi, US FARAON, Andrei, US YANG, Changhuei, US
  • 特許第6230047号:複素振幅画像表示方法、散乱位相画像生成装置および散乱位相画像生成方法    2017年10月27日
    岡本淳, 渋川敦史, 後藤優太
  • 特許第6029167号:ノイズ除去方法およびノイズ除去装置、記録再生方法および記録再生装置、ならびに、画像計測方法および画像計測装置    2016年10月28日
    岡本 淳, 渋川 敦史, 若山 雄太
  • 特開WO2015068834:複素振幅像生成装置および複素振幅像生成方法  2015年05月14日
    岡本 淳, 渋川敦史
  • 特開WO/2013/008453:ホログラフィックメモリの記録方法および再生方法ならびにホログラフィックメモリの記録装置および再生装置  2013年01月17日
    岡本淳, 瑞慶覧圭佑, 高林正典, 渋川敦史

受賞

  • 2021年02月 公益財団法人コニカミノルタ科学技術振興財団 令和2年度コニカミノルタ画像科学奨励賞
     世界最速一次元空間光変調器の開発と光波面シェイピングへの応用 
    受賞者: 渋川 敦史

教育活動情報

主要な担当授業

  • 量子力学
    開講年度 : 2021年
    課程区分 : 学士課程
    開講学部 : 工学部
    キーワード : シュレーディンガー方程式、波動関数、ポテンシャル井戸内の粒子、フェルミ粒子とボーズ粒子、物理量演算子、角運動量とスピン、不確定性原理、状態密度


Copyright © MEDIA FUSION Co.,Ltd. All rights reserved.