研究者情報

マスター

アカウント（マスター）

• 氏名

  坂本　圭太(サカモト　ケイタ), サカモト　ケイタ

所属（マスター）

• 北海道大学病院　放射線科

所属（マスター）

• 北海道大学病院　放射線科

独自項目

syllabus

• 2021, 基本医学研究, Master's Thesis Research in Medical Sciences, 修士課程, 医学院, 画像診断、CT、MRI、PET、SPECT、血管造影、超音波、IVR、RI内用療法
• 2021, 基本医学総論, Basic Principles of Medicine, 修士課程, 医学院, 画像診断、CT、MRI、PET、SPECT、血管造影、超音波、IVR、RI内用療法
• 2021, 医学総論, Principles of Medicine, 博士後期課程, 医学院, 画像診断、CT、MRI、PET、SPECT、血管造影、超音波、IVR、RI内用療法
• 2021, 基盤医学研究, Dissertation Research in Medical Sciences, 博士後期課程, 医学院, 画像診断、CT、MRI、PET、SPECT、血管造影、超音波、IVR、RI内用療法
• 2021, 臨床医学研究, Dissertation Research in Clinical Medicine, 博士後期課程, 医学院, 画像診断、CT、MRI、PET、SPECT、血管造影、超音波、IVR、RI内用療法

researchmap

プロフィール情報

学位

• 博士（医学）（北海道大学）

プロフィール情報

• 姓

  坂本

• 名

  圭太

• ID各種

  201801018750136618

業績リスト

研究分野

• ライフサイエンス / 放射線科学

論文

• 術前検査で偶発的に発見されたMinute pulmonary meningothelial-like nodulesの1例

  小林 圭太, 吉川 仁人, 高柳 歩, 常田 慧徳, 中川 純一, 木村 理奈, 西岡 典子, 坂本 圭太, 加藤 扶美, 岡崎 ななせ, 松野 吉宏, 氏家 秀樹, 工藤 與亮

  北海道放射線医学雑誌 4 25 - 29 (NPO)メディカルイメージラボ 2024年03月 

  症例は70代男性。肺癌に対する術前精査目的のCTで両肺に3mm前後のすりガラス状微小結節を多数認めた。一部の結節では内部に空洞を伴っていた。右上葉肺腺癌に対して右肺上葉切除術が施行され、病理組織学的にはMinute pulmonary meningothelial-like nodule(MPMN)の多発が確認された。MPMNは組織学的に髄膜腫細胞と類似の形態を示す比較的稀な肺良性病変であり、両肺にすりガラス状の微小結節を複数認めた場合には鑑別にあげるべき疾患の一つとして考慮する必要がある。病変が空洞を伴う場合にはMPMNがより示唆される可能性はあるが、MPMNはその他の特異的な画像所見に乏しく、一般に転移性肺腫瘍を含めた悪性病変との厳密な鑑別は画像のみでは困難であり、長期間の経過観察が望ましい。(著者抄録)
• 低血糖発作を合併した胸膜孤立性線維性腫瘍の1例

  村本 朋之, 中川 純一, 常田 慧徳, 高橋 文也, 木村 理奈, 西岡 典子, 坂本 圭太, 加藤 扶美, 氏家 秀樹, 加藤 達哉, 大藤 悠里, 亀田 啓, 中村 昭伸, 若林 健人, 松野 吉宏, 工藤 與亮

  Japanese Journal of Radiology 42 Suppl. 4 - 4 (公社)日本医学放射線学会 2024年02月
• 低血糖発作を合併した胸膜孤立性線維性腫瘍の1例

  村本 朋之, 中川 純一, 常田 慧徳, 高橋 文也, 木村 理奈, 西岡 典子, 坂本 圭太, 加藤 扶美, 氏家 秀樹, 加藤 達哉, 大藤 悠里, 亀田 啓, 中村 昭伸, 若林 健人, 松野 吉宏, 工藤 與亮

  Japanese Journal of Radiology 42 Suppl. 4 - 4 (公社)日本医学放射線学会 2024年02月
• Clinical utility of single-shot echo-planar diffusion-weighted imaging using L1-regularized iterative sensitivity encoding in prostate MRI.

  Noriko Nishioka, Noriyuki Fujima, Satonori Tsuneta, Masami Yoneyama, Ryuji Matsumoto, Takashige Abe, Rina Kimura, Keita Sakamoto, Fumi Kato, Kohsuke Kudo

  Medicine 102 17 e33639  2023年04月25日 

  We investigated the ability of echo-planar imaging with L1-regularized iterative sensitivity encoding-based diffusion-weighted imaging (DWI) to improve the image quality and reduce the scanning time in prostate magnetic resonance imaging. We retrospectively analyzed 109 cases of prostate magnetic resonance imaging. We compared variables in the quantitative and qualitative assessments among 3 imaging groups: conventional parallel imaging-based DWI (PI-DWI) with an acquisition time of 3 minutes 15 seconds; echo-planar imaging with L1-regularized iterative sensitivity encoding-based DWI (L1-DWI) with a normal acquisition time (L1-DWINEX12) of 3 minutes 15 seconds; and L1-DWI with a half acquisition time (L1-DWINEX6) of 1 minute 45 seconds. As a quantitative assessment, the signal-to-noise ratio (SNR) of DWI (SNR-DWI), the contrast-to-noise ratio (CNR) of DWI (CNR-DWI), and the CNR of apparent diffusion coefficient were measured. As a qualitative assessment, the image quality and visual detectability of prostate carcinoma were evaluated. In the quantitative analysis, L1-DWINEX12 showed significantly higher SNR-DWI than PI-DWI (P = .0058) and L1-DWINEX6 (P < .0001). In the qualitative analysis, the image quality score for L1-DWINEX12 was significantly higher than those of PI-DWI and L1-DWINEX6. A non-inferiority assessment demonstrated that L1-DWINEX6 was non-inferior to PI-DWI in terms of both quantitative CNR-DWI and qualitative grading of image quality with a <20% inferior margin. L1-DWI successfully demonstrated a reduced scanning time while maintaining good image quality.
• 胸膜孤立性線維性腫瘍に合併したDoege-potter症候群の一例

  村本 朋之, 中川 純一, 常田 慧徳, 高橋 文也, 木村 理奈, 西岡 典子, 坂本 圭太, 加藤 扶美, 氏家 秀樹, 加藤 達哉, 大藤 悠理, 亀田 啓, 中村 昭伸, 若林 健人, 松野 吉宏, 工藤 與亮

  北海道放射線医学雑誌 3 28 - 32 (NPO)メディカルイメージラボ 2023年03月 

  症例は60歳代女性。X-1年の検診で右胸部に異常影を指摘された。X年に胸部異常影増大と空腹時血糖38mg/dLの著明低値を認めたため前医を受診し、CTで右胸腔下部を占拠する巨大腫瘤を認めた。針生検で孤立性線維性腫瘍(solitary fibrous tumor:SFT)が疑われたため、手術目的に当院呼吸器外科に紹介受診となった。入院後低血糖時の採血でinsulinとC-peptideの低下を認めた。腫瘍はMRIではT2強調像で低信号を主体として高信号が混在し、内部にflow voidを認めた。造影後T1強調像では強く増強され、内部に血管が発達していた。腫瘍摘出術が施行され、SFTの確定診断となった。術前に頻発していた低血糖は術直後から消失し、SFTに伴う非膵島細胞腫瘍性低血糖症と考えられた。本病態はDoege-Potter症候群として知られ、SFTの5%以下の症例で生じるとされる。低血糖を合併した軟部腫瘍ではSFTが鑑別のひとつに挙げられる。(著者抄録)
• Rheumatologic manifestations with elevated levels of IL-6, IL-17A, and IL-23 in a patient with scurvy

  Masahiro Ueki, Keita Sakamoto, Noriko Nishioka, Hiroki Ohata, Takiko Nobuta, Shunichiro Takezaki, Atsushi Manabe, Masafumi Yamada

  Modern Rheumatology Case Reports 2022年08月09日 

  ABSTRACT Symptomatic vitamin C deficiency, scurvy, is a relatively rare disease in developed countries, but it has been reported in patients with autism spectrum disorder or developmental delay who tend to have selective diets. Patients with scurvy often demonstrate musculoskeletal manifestations with unknown pathophysiology. Herein, we report a case of scurvy in an 11-year-old boy who presented with iron-deficiency anaemia, systemic osteomyelitis, myositis predominantly in the lower extremities, and right ventricular volume overload with mild pulmonary hypertension and was diagnosed with scurvy. He had a mild developmental disorder and a selective diet, which resulted in severe vitamin C deficiency. He received intravenous and oral vitamin C supplementation, which relieved his arthralgia and muscle pain in a week. Following 4 months of vitamin C supplementation, he demonstrated no abnormal manifestations on laboratory or imaging examination and recovered without sequelae. Inflammatory cytokine and chemokine evaluations demonstrated elevated levels of interleukin (IL)-6, IL-17A, and IL-23, which are associated with T-helper (Th) 17 cell activation. This study is the first to suggest the association between the inflammation seen in scurvy, rheumatic manifestations in the patient, and Th17 cell activation. Further analysis of the association between the inflammation and vitamin C supplementation may contribute to new insights for the comprehension and treatment of other inflammatory diseases, such as rheumatic diseases.
• 腫瘍性骨軟化症に対してブロスマブを使用した3例

  宮崎 あすか, 亀田 啓, 大江 悠希, 泉原 里美, 重沢 郁美, 野本 博司, 曹 圭龍, 中村 昭伸, 坂本 圭太, 森田 亮, 曽山 武士, 阿保 大介, 工藤 與亮, 三好 秀明, 渥美 達也

  日本内分泌学会雑誌 97 2 521 - 521 (一社)日本内分泌学会 2021年10月
• Favorable Effects of Burosumab on Fibroblast Growth Factor 23-Related Osteomalacia: A Case Report

  Yuki Oe, Hiraku Kameda, Hiroshi Nomoto, Keita Sakamoto, Takeshi Soyama, Kyu Yong Cho, Akinobu Nakamura, Daisuke Abo, Kohsuke Kudo, Tatsuya Atsumi, Hideaki Miyoshi

  Journal of the Endocrine Society 5 Supplement_1 A194 - A194 2021年05月03日 

  Background: Fibroblast growth factor 23 (FGF23) decreases serum phosphate levels by inhibiting proximal tubular phosphate reabsorption and intestinal phosphate absorption by decreasing serum 1,25-dihydroxyvitamin D level, thereby regulating phosphate metabolism. Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by FGF23 overproduction by tumor tissue. Resecting the responsible tumor is a radical treatment for TIO. When the responsible tumor is undetectable, phosphate and active vitamin D administration is recommended. However, supplementation alone is frequently insufficient to maintain phosphate levels and it is difficult to prevent the complications associated with medical therapy, including hypercalciuria and nephrocalcinosis. Recently, burosumab, a human monoclonal anti-FGF23 antibody, has been approved in Japan as a therapeutic agent for FGF23-related hypophosphatemia. Here, we present a patient with TIO effectively treated with burosumab in the absence of identification of tumour location. Clinical case: A 47-year-old female developed pain and edema of the feet; however, the cause could not be determined at local hospitals. Afterwards, she developed marked bone atrophy in the feet and was referred to our hospital. Her age at symptom onset, hypophosphatemia (serum P, 1.9 mg/dl, 2.7 mg/dl &lt; n &lt; 4.6 mg/dl), high serum FGF23 level (630 pg/ml, 16 pg/ml &lt; n &lt; 69 pg/ml), and decreased 1,25-dihydroxyvitamin D level (12.9 pg/ml, 20 pg/ml &lt; n &lt; 60 pg/ml) indicated FGF23-related osteomalacia. She was not having any medication at the time of diagnosis, including saccharified iron oxide or iron polymaltose. Urinary phosphate excretion increased without renal tubular defect; therefore, hypophosphatemic osteomalacia was diagnosed. MRI showed high signal intensity in the talus, sacral, and L5 vertebral regions, indicating multiple pseudofractures. Comprehensive imaging studies, including systemic CT scan and 111In-pentetreotide scintigraphy, did not reveal any tumors despite the suspicion of TIO. Next, we performed systemic venous sampling, which revealed high FGF23 level in the left external iliac vein. Second venous sampling limited to the left lower limb exhibited high FGF23 level in the posterior tibial vein. However, an additional imaging study limited to the left foot could not identify any tumors. Genetic variation was negative for potentially responsible genes, including PHEX and FGF23. We decided to administer burosumab to normalize serum phosphate level without phosphate supplementation. Within 2 months, pain was relieved and the visual analog scale scores also improved from 10 to 6. Moreover, bone MRI showed improved pseudofractures. Conclusion: Burosumab administration was effective for TIO of unknown origin, and it improved not only laboratory findings but also clinical symptoms in this case.
• 全身MRI・骨シンチを用いた特発性大腿骨頭壊死症患者の多発骨壊死の評価

  横田 隼一, 清水 智弘, 坂本 圭太, 清水 幸衣, 浅野 毅, 高橋 大介, 工藤 與亮, 岩崎 倫政

  日本整形外科学会雑誌 95 3 S968 - S968 (公社)日本整形外科学会 2021年03月
• 全身MRI・骨シンチを用いた特発性大腿骨頭壊死症患者の多発骨壊死の評価

  横田 隼一, 清水 智弘, 坂本 圭太, 清水 幸衣, 中村 夢志郎, 高橋 要, 浅野 毅, 高橋 大介, 工藤 與亮, 岩崎 倫政

  日本リウマチ学会北海道・東北支部学術集会抄録集 30回 57 - 57 (一社)日本リウマチ学会-北海道・東北支部 2021年02月
• 全身MRI・骨シンチを用いた特発性大腿骨頭壊死症患者の多発骨壊死の評価

  横田 隼一, 清水 智弘, 浅野 毅, 高橋 大介, 岩崎 倫政, 坂本 圭太, 清水 幸衣, 工藤 與亮

  北海道整形災害外科学会雑誌 63 139th suppl 92 - 92 北海道整形災害外科学会 2021年
• 抗FGF23抗体が奏功したFGF23関連低リン血症性骨軟化症の一例

  大江 悠希, 亀田 啓, 家坂 光, 泉原 里美, 上垣 里紗, 亀田 玲奈, 野本 博司, 坂本 圭太, 曽山 武士, 曹 圭龍, 中村 昭伸, 阿保 大介, 工藤 與亮, 三好 秀明, 渥美 達也

  日本内分泌学会雑誌 96 2 529 - 529 (一社)日本内分泌学会 2020年10月
• 画像診断と病理 粘液線維肉腫

  原嶋 十考, 中川 純一, 原田 太以佑, 坂本 圭太, 工藤 與亮, 中里 信一, 清水 亜衣

  画像診断 40 12 1158 - 1159 (株)学研メディカル秀潤社 2020年09月
• AIDS患者に発症した肝EBV関連平滑筋腫の1例

  金谷 本真, 坂本 圭太, 加藤 扶美, 真鍋 徳子, 工藤 興亮, 笠原 耕平, 荒 隆英, 高桑 恵美, 桑原 健

  Japanese Journal of Radiology 38 Suppl. 8 - 8 (公社)日本医学放射線学会 2020年02月
• Myofascia-dominant involvement on whole-body MRI as a risk factor for rapidly progressive interstitial lung disease in dermatomyositis.

  Karino K, Kono M, Kono M, Sakamoto K, Fujieda Y, Kato M, Amengual O, Oku K, Yasuda S, Atsumi T

  Rheumatology (Oxford, England) 59 7 1734 - 1742 2020年01月 [査読有り][通常論文]
   

  OBJECTIVE: Rapidly progressive interstitial lung disease (RPILD) is a major cause of death in patients with DM. Although clinically amyopathic DM (CADM) represents risk for RPILD, the incidence rate of RPILD in patients with CADM varies widely. Whole-body (WB) MRI can reveal involvement of systemic muscle and myofascia. The objective of this study was to explore the risk factors for RPILD in patients with DM using WB-MRI. METHODS: This retrospective study comprised 41 patients with DM who underwent WB-MRI before the initiation of treatment in our hospital. Muscular and myofascial signals were scored on 42 muscular groups. The myofascia/muscle ratio was calculated and used to define the relevance of myofascia-dominant involvement. RPILD was defined as worsening of dyspnoea, hypoxaemia and radiographic ILD/fibrosis within 3 months from the onset of respiratory symptoms. RESULTS: Among the 41 patients, 17 had CADM and 30 had ILD, including 10 patients with RPILD. All patients including those with CADM showed abnormal signal intensity in both muscle and myofascia (median score: 15 and 23, respectively). Muscle signal scores positively correlated with the serum creatine kinase level (r = 0.714; P< 0.001). Patients with RPILD showed a significantly higher myofascia/muscle ratio than those without RPILD (1.929 vs 1.200; P= 0.027). Logistic regression analysis identified higher myofascia/muscle ratio as independent risk factors for developing RPILD. CONCLUSION: Myofascia-dominant involvement was defined and appreciated in patients with DM using WB-MRI. This may be one of the risk factors for RPILD.
• Heterogeneity of longitudinal and circumferential contraction in relation to late gadolinium enhancement in hypertrophic cardiomyopathy patients with preserved left ventricular ejection fraction.

  Keita Sakamoto, Noriko Oyama-Manabe, Osamu Manabe, Tadao Aikawa, Yasuka Kikuchi, Harue Sasai-Masuko, Masanao Naya, Kohsuke Kudo, Fumi Kato, Nagara Tamaki, Hiroki Shirato

  Japanese journal of radiology 36 2 103 - 112 2018年02月 [査読有り][通常論文]
   

  PURPOSE: To evaluate heterogeneity of myocardial contraction in relation to extensive late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM) patients with preserved left ventricular ejection fraction, using fast strain-encoded magnetic resonance imaging. MATERIALS AND METHODS: Twenty-two HCM patients and 24 age-matched control subjects were included in this retrospective study. The regional and global peak values of longitudinal and circumferential strain (LSregional, LSglobal, CSregional, CSglobal), and their regional heterogeneities were evaluated using coefficients of variation (LSCoV, CSCoV) in relation to LGE. Receiver operating characteristic curve analysis was performed to identify patients with a total left ventricular myocardial LGE ≥ 15%. RESULTS: LSglobal in HCM patients was significantly decreased compared to that in controls (- 14.4 ± 2.4% vs - 17.2 ± 2.0%; p = 0.0004), while CSglobal was not (p = 1.0). Negative LGE segments demonstrated decreased LSregional in HCM patients compared to in controls (p < 0.0001), while CSregional was not decreased. CSCoV demonstrated the largest area under the curve (AUC) (0.91), with high sensitivity (83%) and specificity (94%) for detection of HCM patients with extensive LGE, while the AUC of LSCoV was low (0.49). CONCLUSION: The heterogeneity in CSregional has a high diagnostic value for detection of HCM patients with extensive LGE.
• Relapsing Polychondritis With Increased Bone Marrow Signal on Magnetic Resonance Imaging in a 13-Year-Old Girl.

  Kanako Nakayama, Sayaka Yamamoto, Kimiaki Uetake, Masafumi Yamada, Yusuke Tozawa, Masahiro Ueki, Shunichiro Takezaki, Hiroki Nishimura, Yuji Nakamaru, Tomoko Mitsuhashi, Noriko Oyama-Manabe, Keita Sakamoto, Ryuta Arai, Tadashi Ariga

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 24 1 52 - 54 2018年01月 [査読有り][通常論文]
  
• Effectiveness of whole-body magnetic resonance imaging for the efficacy of biologic anti-rheumatic drugs in patients with rheumatoid arthritis: A retrospective pilot study

  Michihito Kono, Tamotsu Kamishima, Shinsuke Yasuda, Keita Sakamoto, Sawako Abe, Atsushi Noguchi, Toshiyuki Watanabe, Yuka Shimizu, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Tatsuya Atsumi

  MODERN RHEUMATOLOGY 27 6 953 - 960 2017年 [査読有り][通常論文]
   

  Objectives: To evaluate the scoring of whole-body magnetic resonance imaging (WBMRI) for efficacy assessment in rheumatoid arthritis (RA) patients receiving biological disease-modifying anti-rheumatic drugs (bDMARDs).Methods: Thirty consecutive RA patients receiving bDMARDs were included in this retrospective study. Contrast WBMRI was performed before and 1 year after bDMARDs initiation.Results: At baseline, mean age was 57.1 years and mean disease duration was 3.0 years. Median disease activity score in 28 joints improved from 5.1 to 2.1. Treatment with bDMARDs improved mean whole-body synovitis score from 31.2 to 23.2 and median whole-body bone-edema score from 11 to 3. Whole-body bone-erosion score improved in seven patients and deteriorated in 17 patients. Logistic regression analysis identified whole-body synovitis score as a poor prognostic factor for whole-body bone-erosion progression. Bone-edema score in individual bones was identified as a poor prognostic factor for the progression of bone-erosion. Changes in hand synovitis score correlated with those of other joints, but neither changes in bone-edema nor erosion score of hands correlated with those of other joints in WBMRI.Conclusions: WBMRI scoring may be a novel useful tool to evaluate the efficacy of anti-rheumatic drugs, as well as a potential predictor of joint prognosis, in patients with RA.
• CTが診断に有用であった繰り返す消化管出血症例

  亀田 浩之, 真鍋 徳子, 菊池 穏香, 坂本 圭太, 三村 理恵, 加藤 扶美, 工藤 與亮, 藪崎 哲史, 宮本 憲幸, 西田 睦, 畑中 佳奈子, 大野 正芳, 高橋 典彦

  Japanese Journal of Radiology 34 Suppl. 3 - 3 (公社)日本医学放射線学会 2016年02月
• Observational cohort study of first-line bevacizumab with oxaliplatin or irinotecan and fluoropyrimidines in metastatic colorectal cancer: HGCSG0802-Analysis of early tumor shrinkage (ETS).

  Yuki Satoshi, Nakatsumi Hiroshi, Sawada Kentaro, Kato Takashi, Meguro Takashi, Nakamura Michio, Iwanaga Ichiro, Ehira Nobuyuki, Sonoda Norikazu, Kudo Mineo, Kato Kanji, Sogabe Susumu, Amano Toraji, Ono Kota, Sakamoto Keita, Miyamoto Noriyuki, Kudo Kohsuke, Sakamoto Naoya, Sakata Yuh, Komatsu Yoshito

  JOURNAL OF CLINICAL ONCOLOGY 34 4 2016年02月01日 [査読有り][通常論文]
  
• Strategic Approach to the Splenic Artery in Laparoscopic Spleen-preserving Distal Pancreatectomy

  Kazuho Inoko, Yuma Ebihara, Keita Sakamoto, Noriyuki Miyamoto, Yo Kurashima, Eiji Tamoto, Toru Nakamura, Soichi Murakami, Takahiro Tsuchikawa, Keisuke Okamura, Toshiaki Shichinohe, Satoshi Hirano

  SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES 25 4 E122 - E125 2015年08月 [査読有り][通常論文]
   

  Background:Laparoscopic spleen-preserving distal pancreatectomy (LSPDP) is an ideal procedure in selected patients with benign or low-grade malignant tumors in the body/tail of the pancreas. We describe our procedure and experience with splenic vessel-preserving LSPDP (SVP-LSPDP) in a retrospective case series.Methods:Six consecutive patients underwent SVP-LSPDP from January 2011 to September 2013. We evaluated the courses of the splenic artery by preoperative computed tomography and applied an individualized approach (the superior approach or inferior approach) to the splenic artery.Results:All of the operations were successful. The median surgical duration was 249 minutes. The median blood loss was 0 mL. Pathologic examination revealed 4 cases of insulinoma, 1 case of solid pseudopapillary tumor, and 1 case of pancreatic metastasis from renal carcinoma.Conclusions:In performing SVP-LSPDP, it is effective to make a strategic choice between 2 different approaches according to the course of splenic artery.
• 発熱と骨病変が先行した小児白血病の1例

  藪崎 哲史, 宮本 憲幸, 白土 博樹, 真鍋 徳子, 藤間 憲幸, 菊池 穏香, 坂本 圭太, 三村 理恵, 加藤 芙美, 工藤 與亮, 佐藤 智信, 長 祐子, 井口 晶裕

  Japanese Journal of Radiology 33 Suppl. 2 - 2 (公社)日本医学放射線学会 2015年02月
• Prediction of pancreatic anastomotic failure after pancreatic head resection using preoperative diffusion-weighted MR imaging

  Noriyuki Miyamoto, Satoshi Yabusaki, Keita Sakamoto, Yasuka Kikuchi, Rie Mimura, Fumi Kato, Noriko Oyama-Manabe, Bunya Takahashi, Takeshi Soyama, Daisuke Abo, Yusuke Sakuhara, Kohsuke Kudo, Hiroki Shirato, Toru Nakamura, Takahiro Tsuchikawa, Keisuke Okamura, Satoshi Hirano

  JAPANESE JOURNAL OF RADIOLOGY 33 2 59 - 66 2015年02月 [査読有り][通常論文]
   

  To determine whether the preoperative pancreatic apparent diffusion coefficient (ADC) can be used to predict the development of postoperative pancreatic anastomotic failure (PAF). We retrospectively examined the cases of 79 patients who underwent pancreatic head resection between January 2010 and October 2013. The patients underwent 1.5-T MR imaging including diffusion-weighted imaging before surgery. The main pancreatic duct diameter (MPD), the pancreatic parenchymal thickness (PT), and the ADC of the pancreatic remnant parenchyma were measured. Two radiologists blinded to the patients' outcomes performed the measurements. The imaging parameters were compared between the patients who developed PAF and those who did not. The cut-off ADC for the development of PAF was calculated with a receiver operating characteristic analysis. The imaging parameters were highly correlated between the two observers. The MPD and PT did not differ significantly among the patients. The mean pancreatic ADCs were significantly higher in the patients with PAF than in those without PAF. An ADC higher than 1.50 x 10(-3) mm(2)/s (Az = 0.719, observer-1) or 1.35 x 10(-3) mm(2)/s (Az = 0.752, observer-2) was optimal for predicting the development of postoperative PAF. Measuring the preoperative non-tumorous pancreatic ADC may be useful for the prediction of a postoperative PAF.
• Association of early tumor shrinkage with progression-free survival in patients with metastatic colorectal cancer treated with bevacizumab-based chemotherapy: HGCSG0802.

  Nakatsumi Hiroshi, Yuki Satoshi, Muranaka Tetsuhito, Fukushima Hiraku, Kato Takashi, Meguro Takashi, Nakamura Michio, Iwanaga Ichiro, Ehira Nobuyuki, Sonoda Norikazu, Kudo Mineo, Kato Kanji, Miyashita Kencho, Abe Masakazu, Miyamoto Noriyuki, Sakamoto Keita, Kudo Kohsuke, Sakamoto Naoya, Sakata Yuh, Komatsu Yoshito

  JOURNAL OF CLINICAL ONCOLOGY 33 3 2015年01月20日 [査読有り][通常論文]
  
• 原因病変の多発が疑われた良性腫瘍性骨軟化症の1例 各種モダリティの中での超音波検査の役割

  曽山 武士, 作原 祐介, 坂本 圭太, 高橋 文也, 阿保 大介, 工藤 與亮, 堀江 達則, 西田 睦

  超音波医学 42 1 92 - 92 (公社)日本超音波医学会 2015年01月
• Efficacy of Tocilizumab in Patients with Rheumatoid Arthritis: Sequential Evaluation Using Whole-Body Magnetic Resonance Imaging.

  Michihito Kono, Shinsuke Yasuda, Kazumasa Ohmura, Tomoko Fukui, Sanae Shimamura, Ikuma Nakagawa, Atsushi Noguchi, Haruki Shida, Toshiyuki Watanabe, Yuka Shimizu, Takashi Kurita, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Keita Sakamoto, Tamotsu Kamishima, Tatsuya Atsumi

  ARTHRITIS & RHEUMATOLOGY 66 S518 - S518 2014年10月 [査読有り][通常論文]
  
• 腎腫瘤性病変における造影超音波検査による特徴的造影パターンの検討

  堀江 達則, 西田 睦, 坂本 圭太, 作原 祐介, 佐藤 恵美, 井上 真美子, 工藤 悠輔, 表原 里実, 和田 妙子, 岩井 孝仁, 篠原 信雄, 野々村 克也

  超音波医学 41 1 58 - 59 (公社)日本超音波医学会 2014年01月

MISC

• 術前検査で偶発的に発見されたMinute pulmonary meningothelial-like nodulesの1例

  小林 圭太, 吉川 仁人, 高柳 歩, 常田 慧徳, 中川 純一, 木村 理奈, 西岡 典子, 坂本 圭太, 加藤 扶美, 岡崎 ななせ, 松野 吉宏, 氏家 秀樹, 工藤 與亮 北海道放射線医学雑誌 4 25 -29 2024年03月 

  症例は70代男性。肺癌に対する術前精査目的のCTで両肺に3mm前後のすりガラス状微小結節を多数認めた。一部の結節では内部に空洞を伴っていた。右上葉肺腺癌に対して右肺上葉切除術が施行され、病理組織学的にはMinute pulmonary meningothelial-like nodule(MPMN)の多発が確認された。MPMNは組織学的に髄膜腫細胞と類似の形態を示す比較的稀な肺良性病変であり、両肺にすりガラス状の微小結節を複数認めた場合には鑑別にあげるべき疾患の一つとして考慮する必要がある。病変が空洞を伴う場合にはMPMNがより示唆される可能性はあるが、MPMNはその他の特異的な画像所見に乏しく、一般に転移性肺腫瘍を含めた悪性病変との厳密な鑑別は画像のみでは困難であり、長期間の経過観察が望ましい。(著者抄録)
• 術前診断に苦慮した、骨盤底部から臀部に発生した嚢胞性病変の1例

  中村 友亮, 菊池 穏香, 加藤 扶美, 藪崎 哲史, 坂本 圭太, 三村 理恵, 真鍋 徳子, 工藤 與亮, 岡田 宏美, 本間 重紀, 吉田 雅, 川村 秀樹 Japanese Journal of Radiology 36 (Suppl.) 17 -17 2018年02月 [査読無し][通常論文]
  
• 多彩な造影パターンが混在していた肝細胆管細胞癌の1例

  常田慧徳, 藪崎哲史, 加藤扶美, 菊池穏香, 坂本圭太, 三村理恵, 真鍋徳子, 工藤與亮, 畑中佳奈子 Japanese Journal of Radiology 36 (Supplement) 2018年
• 画像診断に苦慮したHHV8-unrelated primary effusion lymphoma-like lymphomaの1例

  中川 純一, 加藤 扶美, 三村 理恵, 藪崎 哲史, 坂本 圭太, 真鍋 徳子, 工藤 與亮, 菅野 宏美, 松野 吉宏, 豊嶋 崇徳, 金谷 穣, 渡利 英道, 櫻木 範明, 白土 博樹 Japanese Journal of Radiology 35 (Suppl.) 3 -3 2017年02月 [査読無し][通常論文]
  
• MDCTによる膵神経内分泌腫瘍(PNET)の組織学的grade、肝転移に関する検討

  宮本 憲幸, 坂本 圭太, 藪崎 哲史, 亀田 浩之, 豊永 拓哉, 吉野 裕紀, 木村 輔, 菊池 穏香, 三村 理恵, 加藤 扶美, 真鍋 徳子, 工藤 與亮, 土川 貴裕, 中村 透, 岡村 圭祐, 平野 聡 Japanese Journal of Radiology 34 (Suppl.) 13 -13 2016年02月 [査読無し][通常論文]
  
• 3T乳腺MRIにおける拡散尖度画像の検討

  加藤 扶美, 工藤 與亮, 三村 理恵, 藪崎 哲史, 坂本 圭太, 宮本 憲幸, 真鍋 徳子, 藤原 太郎, 杉森 博行, 山下 啓子, 細田 充主, Wang Jeff, 白土 博樹 Japanese Journal of Radiology 34 (Suppl.) 13 -13 2016年02月 [査読無し][通常論文]
  
• 原因病変の多発が疑われた良性腫瘍性骨軟化症の1例

  曽山武士, 作原祐介, 坂本圭太, 高橋文也, 阿保大介, 工藤與亮, 一山芽衣, 渥美達也, 新井隆太, 岩崎倫政 IVR 30 (3) 275 2015年09月20日 [査読無し][通常論文]
  
• 術前MRIによる膵頭部切除後膵液漏発生の検討

  宮本 憲幸, 坂本 圭太, 薮崎 哲史, 高橋 文也, 木村 輔, 亀田 浩之, 菊池 穏香, 三村 理恵, 加藤 扶美, 真鍋 徳子, 工藤 與亮, 白土 博樹, 中村 透, 松本 譲, 岡村 圭祐, 平野 聡 IVR: Interventional Radiology 30 (3) 271 -271 2015年09月 [査読無し][通常論文]
  
• A case of benign tumor-induced osteomalacia that multiple occurrence of the cause lesion was doubted

  SOYAMA Takeshi, SAKUHARA Yusuke, SAKAMOTO Keita, TAKAHASHI Fumiya, ABO Daisuke, KUDO Kosuke, ICHIYAMA Mei, ATSUMI Tatsuya, ARAI Ryuta, IWASAKI Norimasa 日本医学放射線学会秋季臨床大会抄録集 50th S676 2014年09月05日 [査読無し][通常論文]
  
• 正常人における1.5T MRI T2強調横断像での被殻外側の線状高信号の検討

  THA Khin Khin, 寺江聡, 塚原亜希子, 森田亮, 坂本圭太, 原田八重, 古田大介, 財津有里, 藤間憲幸, 白土博樹 Jpn J Radiol 30 (Supplement 1) 1 2012年02月25日 [査読無し][通常論文]
  
• 3次元シミュレーションソフトを用いた肺区域評価が有用だった肺切除2症例

  坂本圭太, 小野寺祐也, 寺江聡, 白土博樹 Jpn J Radiol 30 (Supplement 1) 9 2012年02月25日 [査読無し][通常論文]
  
• MRIを比較画像としたrealtime virtual sonographyを用いた生検が確定診断に有用だった悪性リンパ腫の1例

  坂本圭太, 作原祐介, 阿保大介, 長谷川悠, 曽山武士, 森田亮, 白土博樹, 寺江聡 IVR 27 (1) 72 2012年02月01日 [査読無し][通常論文]
  
• V‐Navi併用造影US下腎生検が確定診断に有用だった血管内リンパ腫(IVL)の1例

  曽山武士, 阿保大介, 作原祐介, 長谷川悠, 森田亮, 坂本圭太, 白土博樹, 寺江聡, 清水匡, 西田睦, 石坂香織 IVR 27 (1) 72 2012年02月01日 [査読無し][通常論文]
  
• ソフトウェアを用いたCT画像からの肺血管の自動描出の試み

  坂本圭太, 小野寺祐也, 寺江聡, 白土博樹 日本医学放射線学会総会抄録集 70th S340 2011年02月28日 [査読無し][通常論文]
  
• 腫瘍におけるtumor doubling timeと糖代謝能の関係

  坂本圭太, 神島保, 尾松徳彦, 小野寺祐也, 白土博樹, 寺江聡, 平田健司, 玉木長良 Jpn J Radiol 28 (Supplement 1) 12 2010年07月25日 [査読無し][通常論文]
  
• 新開発のsoftwareを用いた肺腫瘍のDT計測値の再現性と妥当性評価

  坂本圭太, 神島保, 平田健司, 尾松徳彦, 小野寺祐也, 寺江聡, 玉木長良, 白土博樹 日本医学放射線学会総会抄録集 68th S364-S365 2009年02月28日 [査読無し][通常論文]