研究者データベース

笹岡 一慶(ササオカ カズヨシ)
獣医学研究院 附属動物病院
特任助教

基本情報

所属

  • 獣医学研究院 附属動物病院

職名

  • 特任助教

学位

  • 学士(北海道大学)

J-Global ID

研究キーワード

  • 脳神経内科   犬   画像診断   臨床獣医学   

研究分野

  • ライフサイエンス / 獣医学 / 臨床獣医学
  • ライフサイエンス / 獣医学 / 臨床獣医学
  • ライフサイエンス / 獣医学 / 臨床獣医学

職歴

  • 2019年04月 - 現在 北海道大学大学院 附属動物病院 特任助教
  • 2018年04月 - 2019年03月 北海道大学大学院 獣医学研究科 日本学術振興会 特別研究員DC2
  • 2013年04月 - 2016年03月 田口動物病院 勤務獣医師

学歴

  • 2016年04月 - 2019年03月   北海道大学大学院   獣医学研究科   獣医内科学教室
  • 2007年04月 - 2013年03月   北海道大学   獣医学部   獣医学科
  • 2004年04月 - 2007年03月   群馬県立高崎高等学校   普通科

所属学協会

  • 獣医神経病学会   

研究活動情報

論文

  • Noboru Sasaki, Noriyuki Nagata, Keitaro Morishita, Tatsuyuki Osuga, Kazuyoshi Sasaoka, Nozomu Yokoyama, Hiroshi Ohta, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 82 7 1012 - 1016 2020年07月31日 [査読有り][通常論文]
     
    The feasibility of ultrasonographic measurement of thyroid gland area to common carotid artery (TG:CCA) was investigated. Twenty-one healthy, 12 hypothyroid and 18 non-thyroid illness (NTI) dogs were evaluated. The area of thyroid lobe and common carotid artery in right and left sides were measured using the same ultrasonographic images in transverse plane. The average of the right and left ratio was calculated as TG:CCA. The median TG:CCA of 21 healthy dogs was 1.53, and it did not correlate either body weight or age. The median TG:CCA of 12 hypothyroid dogs was 0.81, which was significantly lower than that of 18 NTI dogs (1.81, P<0.001). If the cut off value <1.12 was used, TG:CCA indicated hypothyroidism with a sensitivity of 100%, specificity of 83%, and accuracy of 90%. Our data indicated that TG:CCA was independent of both body weight, which may contribute to consistent measurement of thyroid size. The results of this study suggest that TG:CCA is a promising tool for diagnosing canine hypothyroidism.
  • Nisa K, Ohta H, Yokoyama N, Tamura M, Nagata N, Sasaoka K, Dermlim A, Leela-Arporn R, Morita T, Osuga T, Sasaki N, Morishita K, Nakamura K, Kagawa Y, Takiguchi M
    The Japanese journal of veterinary research 67 3 221 - 227 2019年08月 [査読有り][通常論文]
     
    Ultra low fat diet (ULFD) has shown a good therapeutic effect in dogs with intestinal lymphangiectasia secondary to CE (IL-CE). As we hypothesized that the mechanism of ULFD may involve the resolution of immunological impairment in IL-CE dogs, our study aimed to investigate the effect of ULFD on the circulating regulatory T cell (Treg) of IL-CE dogs. Treg frequency of pre- and post-ULFD blood samples from dogs with IL-CE (n = 3) were measured using flow cytometry. Treg frequency in IL-CE group before ULFD treatment showed lower tendency when compared to healthy control (mean +/- SD; 2.0 +/- 1.6% and 4.3 +/- 1.4%, respectively), and showed increased tendency after ULFD (mean +/- SD; 4.5 +/- 3.5%). The results suggested that ULFD might restore circulating Treg frequency of IL-CE dogs.
  • Angkhana Dermlim, Tatsuyuki Osuga, Kensuke Nakamura, Tomoya Morita, Khoirun Nisa, Kazuyoshi Sasaoka, Rommaneeya Leela-Arporn, Noriyuki Nagata, Masahiro Tamura, Noboru Sasaki, Hiroshi Ohta, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 81 7 949 - 957 2019年07月11日 [査読有り][通常論文]
     
    The purpose of this study was to evaluate the cardiac acute volume loading effect on left atrial (LA) strain and strain rate (SR) parameters derived from two-dimensional speckle tracking echocardiography (2D-STE) in healthy dogs. Six healthy beagles were anesthetized and subjected to increase cardiac preload by intravenous infusion with lactated Ringer solution at 150 ml/kg/hr for 90 min. A Swan-Ganz catheter was placed to directly measure the mean pulmonary capillary wedge pressure (PCWP). Echocardiography was performed before (baseline) and at 15, 30, 45, 60, 75, and 90 min after acute volume loading began. Apical 4-chamber images focused on the LA were digitally recorded for later strain and SR analysis via 2D-STE. Acute volume loading significantly increased from baseline during LA strain and SR as assessed by the speckle tracking-based technique during reservoir and conduit function at 15 to 90 min after volume load began, and strain indices representing booster pump function were enhanced at 45 to 90 min. In addition, acute volume loading resulted in a significantly greater PCWP after fluid infusion. On multiple regression analysis, quadratic regression analysis was a better fit for the relationship between PCWP and all LA functional indices. Our findings indicated that LA function analyzed by strain and SR was enhanced during cardiac acute volume loading in healthy dogs. The change in strain and SR during acute volume loading should be interpreted with caution during the diagnosis of heart diseases related to volume overload.
  • Rommaneeya Leela-Arporn, Hiroshi Ohta, Masahiro Tamura, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Khoirun Nisa, Tatsuyuki Osuga, Keitaro Morishita, Noboru Sasaki, Mitsuyoshi Takiguchi
    Journal of veterinary internal medicine 33 4 1653 - 1659 2019年07月 [査読有り][通常論文]
     
    BACKGROUND: Metabolomic analysis using blood samples has been suggested to be useful for the early detection of cancer. Among metabolites, plasma-free amino acid (PFAA) profiles are potential diagnostic biomarkers for several diseases including cancer. However, the relationship between PFAA concentrations and liver tumors in dogs remains unknown. OBJECTIVE: To determine the characteristics of PFAA profiles of dogs with hepatocellular carcinoma (HCC) and correlated clinical features. ANIMALS: Thirty-four client-owned dogs diagnosed with HCC (n = 26) and benign liver diseases (n = 8) and 11 age-matched healthy dogs. METHODS: Prospective study using heparinized blood samples from fasted dogs. Plasma was deproteinized, and the concentrations of 21 amino acids were measured using an automated high-performance liquid chromatography amino acid analyzer. RESULTS: Plasma glutamic acid concentrations were significantly different among groups (P < .0024 after Bonferroni correction). Compared to healthy dogs, dogs with HCC and benign liver diseases had significantly higher concentrations of glutamic acid by post hoc analysis. However, no significant difference in the PFAA profiles of HCC and benign liver diseases were detected. In addition, preoperative and postoperative PFAA profiles of dogs with HCC were not significantly different. CONCLUSIONS AND CLINICAL IMPORTANCE: Increased glutamic acid concentrations might play a role in the development or be a consequence of liver tumor formation. However, PFAA profiles of HCC could not be differentiated from those of benign lesions. In addition, glutamic acid concentrations did not change after surgical resection. These results indicate that PFAA profiles may not be useful biomarkers for detecting HCC in dogs.
  • Leela-Arporn R, Ohta H, Nagata N, Sasaoka K, Tamura M, Dermlim A, Nisa K, Morishita K, Sasaki N, Nakamura K, Takagi S, Hosoya K, Takiguchi M
    Veterinary journal (London, England : 1997) 248 74 - 78 2019年06月 [査読有り][通常論文]
  • Dermlim A, Nakamura K, Morita T, Osuga T, Nisa K, Sasaoka K, Leela-arporn R, Sasaki N, Ohta H, Takiguchi M
    Journal of Veterinary Cardiology 23 69 - 80 2019年06月 [査読有り][通常論文]
  • Rommaneeya Leela-Arporn, Hiroshi Ohta, Masahiro Tamura, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Khoirun Nisa, Keitaro Morishita, Noboru Sasaki, Kensuke Nakamura, Satoshi Takagi, Kenji Hosoya, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 81 5 723 - 729 2019年05月31日 [査読有り][通常論文]
     
    A definitive diagnosis of focal liver lesions (FLLs) requires invasive procedures for histopathologic examination. Thus, a simpler noninvasive diagnostic method, such as conventional ultrasonography combined with clinical data, is needed for the prediction of liver malignancy. The objective of this study was to examine the diagnostic accuracy of clinical data and ultrasonographic (US) features to differentiate benign and malignant liver lesions. Medical records and US images from dogs with FLLs that underwent abdominal US and histopathologic examinations following surgery or liver biopsy were retrospectively reviewed. Clinical data, including signalment, clinical signs and laboratory findings, and the US features of liver lesions that could act as predictive factors were assessed using univariate and multivariate analyses to evaluate the associations between predictive factors and liver malignancy. Based on the histopathologic results, 55 dogs with malignant lesions and 28 dogs with benign lesions were included in the study. The results of univariate analysis showed that several US features and platelet count were significantly associated with liver malignancy. Multivariate analysis revealed that the platelet count (thrombocytosis; odds ratio [OR]: 4.13, 95% confidence intervals [CI]: 1.81-9.41), lesion size (4.1 cm or greater; OR: 23.83, 95% CI: 3.74-151.95) and echotexture of FLLs (heterogenous; OR: 8.44; 95% CI: 1.37-51.91) were independent predictors for differentiating benign and malignant liver lesions, suggesting that a combination of clinical data and US findings of FLLs could predict liver malignancy in dogs.
  • Khoirun Nisa, Sue Yee Lim, Masayoshi Shinohara, Tatsuyuki Osuga, Nozomu Yokoyama, Masahiro Tamura, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Rommaneeya Leela-Arporn, Tomoya Morita, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Hiroshi Ohta, Mitsuyoshi Takiguchi
    Journal of veterinary internal medicine 33 2 559 - 568 2019年03月 [査読有り][通常論文]
     
    BACKGROUND: Contrast-enhanced ultrasonography (CEUS) can be used to evaluate intestinal perfusion in healthy dogs. It is helpful for diagnosing and monitoring inflammatory bowel disease in humans and could be useful for dogs with chronic intestinal diseases. OBJECTIVES: To examine duodenal perfusion in dogs with chronic inflammatory enteropathy (CIE) and intestinal lymphoma. ANIMALS: Client-owned dogs with CIE (n = 26) or intestinal lymphoma (n = 7) and dogs with gastrointestinal signs but histopathologically normal duodenum (controls, n = 14). METHODS: In this cross-sectional study, dogs with CIE were classified into remission (n = 16) and symptomatic (n = 10) groups based on clinical scores determined at the time of CEUS. The duodenum was scanned after IV injection of Sonazoid® (0.01 mL/kg). CEUS-derived perfusion parameters, including time-to-peak, peak intensity (PI), area under the curve (AUC), and wash-in and wash-out rates were evaluated. RESULTS: The PI was significantly higher in the symptomatic CIE group (median (range); 105.4 (89.3-128.8) MPV) than in the control group (89.9 (68.5-112.2) MPV). The AUC was significantly higher in the symptomatic CIE group (4847.9 (3824.3-8462.8) MPV.sec) than in the control (3448.9 (1559.5-4736.9) MPV.sec) and remission CIE (3862.3 (2094.5-6899.0) MPV.sec) groups. The PI and clinical score were positively correlated in the CIE group. No significant differences in perfusion parameters were detected between the lymphoma and CIE groups or the lymphoma and control groups. CONCLUSIONS AND CLINICAL IMPORTANCE: The PI and AUC can detect duodenal inflammation and hence are potentially useful for excluding a diagnosis of CIE.
  • Khoirun Nisa, Sue Yee Lim, Masayoshi Shinohara, Tatsuyuki Osuga, Nozomu Yokoyama, Masahiro Tamura, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Rommaneeya Leela-Arporn, Tomoya Morita, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Hiroshi Ohta, Mitsuyoshi Takiguchi
    Journal of veterinary internal medicine 33 2 559 - 568 2019年03月 [査読有り][通常論文]
     
    BACKGROUND: Contrast-enhanced ultrasonography (CEUS) can be used to evaluate intestinal perfusion in healthy dogs. It is helpful for diagnosing and monitoring inflammatory bowel disease in humans and could be useful for dogs with chronic intestinal diseases. OBJECTIVES: To examine duodenal perfusion in dogs with chronic inflammatory enteropathy (CIE) and intestinal lymphoma. ANIMALS: Client-owned dogs with CIE (n = 26) or intestinal lymphoma (n = 7) and dogs with gastrointestinal signs but histopathologically normal duodenum (controls, n = 14). METHODS: In this cross-sectional study, dogs with CIE were classified into remission (n = 16) and symptomatic (n = 10) groups based on clinical scores determined at the time of CEUS. The duodenum was scanned after IV injection of Sonazoid® (0.01 mL/kg). CEUS-derived perfusion parameters, including time-to-peak, peak intensity (PI), area under the curve (AUC), and wash-in and wash-out rates were evaluated. RESULTS: The PI was significantly higher in the symptomatic CIE group (median (range); 105.4 (89.3-128.8) MPV) than in the control group (89.9 (68.5-112.2) MPV). The AUC was significantly higher in the symptomatic CIE group (4847.9 (3824.3-8462.8) MPV.sec) than in the control (3448.9 (1559.5-4736.9) MPV.sec) and remission CIE (3862.3 (2094.5-6899.0) MPV.sec) groups. The PI and clinical score were positively correlated in the CIE group. No significant differences in perfusion parameters were detected between the lymphoma and CIE groups or the lymphoma and control groups. CONCLUSIONS AND CLINICAL IMPORTANCE: The PI and AUC can detect duodenal inflammation and hence are potentially useful for excluding a diagnosis of CIE.
  • Khoirun Nisa, Sue Yee Lim, Tatsuyuki Osuga, Nozomu Yokoyama, Masahiro Tamura, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Rommaneeya Leela-Arporn, Tomoya Morita, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Hiroshi Ohta, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 80 3 453 - 459 2018年03月24日 [査読有り][通常論文]
     
    Quantitative contrast-enhanced ultrasonography (CEUS) enables non-invasive and objective evaluation of intestinal perfusion by quantifying the intensity of enhancement on the intestine after microbubble contrast administration. During CEUS scanning, sedation is sometimes necessary to maintain animal cooperation. Nevertheless, the effect of sedative administration on the canine intestinal CEUS is unknown. This study aimed to investigate the effect of sedation with a combination of butorphanol and midazolam on the duodenal CEUS-derived perfusion parameters of healthy dogs. For this purpose, duodenum was imaged following contrast administration (Sonazoid®, 0.01 ml/kg) in six healthy beagles before and after intravenous injection of a combination of butorphanol (0.2 mg/kg) and midazolam (0.1 mg/kg). Furthermore, hemodynamic parameters including blood pressure and heart rate were recorded during the procedure. Five CEUS derived perfusion parameters including time-to-peak (TTP), peak intensity (PI), area under the curve (AUC), wash-in and wash-out rates (WiR and WoR, respectively) before and after sedation were statistically compared. The result showed that no significant change was detected in any of perfusion parameters. Systolic and mean arterial pressures significantly reduced after sedative administration, but diastolic arterial pressure and heart rate did not significantly change. Moreover, no significant partial correlation was observed between perfusion parameters and hemodynamic parameters. Thus, we concluded that the combination did not cause significant influence in duodenal CEUS perfusion parameters and could be a good option for sedation prior to duodenal CEUS in debilitated dogs.
  • Khoirun Nisa, Sue Yee Lim, Tatsuyuki Osuga, Nozomu Yokoyama, Masahiro Tamura, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Rommaneeya Leela-Arporn, Tomoya Morita, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Hiroshi Ohta, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 80 3 453 - 459 2018年03月24日 [査読有り][通常論文]
     
    Quantitative contrast-enhanced ultrasonography (CEUS) enables non-invasive and objective evaluation of intestinal perfusion by quantifying the intensity of enhancement on the intestine after microbubble contrast administration. During CEUS scanning, sedation is sometimes necessary to maintain animal cooperation. Nevertheless, the effect of sedative administration on the canine intestinal CEUS is unknown. This study aimed to investigate the effect of sedation with a combination of butorphanol and midazolam on the duodenal CEUS-derived perfusion parameters of healthy dogs. For this purpose, duodenum was imaged following contrast administration (Sonazoid®, 0.01 ml/kg) in six healthy beagles before and after intravenous injection of a combination of butorphanol (0.2 mg/kg) and midazolam (0.1 mg/kg). Furthermore, hemodynamic parameters including blood pressure and heart rate were recorded during the procedure. Five CEUS derived perfusion parameters including time-to-peak (TTP), peak intensity (PI), area under the curve (AUC), wash-in and wash-out rates (WiR and WoR, respectively) before and after sedation were statistically compared. The result showed that no significant change was detected in any of perfusion parameters. Systolic and mean arterial pressures significantly reduced after sedative administration, but diastolic arterial pressure and heart rate did not significantly change. Moreover, no significant partial correlation was observed between perfusion parameters and hemodynamic parameters. Thus, we concluded that the combination did not cause significant influence in duodenal CEUS perfusion parameters and could be a good option for sedation prior to duodenal CEUS in debilitated dogs.
  • K. Sasaoka, K. Nakamura, T. Osuga, T. Morita, N. Yokoyama, K. Morishita, N. Sasaki, H. Ohta, M. Takiguchi
    Journal of Veterinary Internal Medicine 32 1 314 - 323 2018年01月01日 [査読有り][通常論文]
     
    Background: Transcranial Doppler ultrasound examination (TCD) is a rapid, noninvasive technique used to evaluate cerebral blood flow and is useful for the detection of intracranial hypertension in humans. However, the clinical usefulness of TCD in diagnosing intracranial hypertension has not been demonstrated for intracranial diseases in dogs. Objectives: To determine the association between the TCD variables and intracranial hypertension in dogs with intracranial diseases. Animals: Fifty client-owned dogs with neurologic signs. Methods: Cross-sectional study. All dogs underwent TCD of the basilar artery under isoflurane anesthesia after magnetic resonance imaging (MRI). Dogs were classified into 3 groups based on MRI findings: no structural diseases (group I), structural disease without MRI evidence of intracranial hypertension (group II), and structural disease with MRI evidence of intracranial hypertension (group III). The TCD vascular resistance variables (resistive index [RI], pulsatility index [PI], and the ratio of systolic to diastolic mean velocity [Sm/Dm]) were measured. Results: Fifteen, 22, and 13 dogs were classified into groups I, II, and III, respectively. Dogs in group III had significantly higher Sm/Dm (median, 1.78 range, 1.44–2.58) than those in group I (median, 1.63 range, 1.43–1.75) and group II (median, 1.62 range, 1.27–2.10). No significant differences in RI and PI were identified among groups. Conclusions and Clinical Importance: Our findings suggest that increased Sm/Dm is associated with MRI findings of suspected intracranial hypertension in dogs with intracranial diseases and that TCD could be a useful tool to help to diagnose intracranial hypertension.
  • Khoirun Nisa, Sue Yee Lim, Masayoshi Shinohara, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Rommaneeya Leela-Arporn, Tomoya Morita, Nozomu Yokoyama, Tatsuyuki Osuga, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Hiroshi Ohta, Mitsuyoshi Takiguchi
    The Journal of veterinary medical science 79 9 1585 - 1590 2017年09月29日 [査読有り][通常論文]
     
    Contrast-enhanced ultrasonography (CEUS) with microbubbles as a contrast agent allows the visualization and quantification of tissue perfusion. The assessment of canine intestinal perfusion by quantitative CEUS may provide valuable information for diagnosing and monitoring chronic intestinal disorders. This study aimed to assess the repeatability (intraday variability) and reproducibility (interday variability) of quantitative duodenal CEUS in healthy dogs. Six healthy beagles underwent CEUS three times within one day (4-hr intervals) and on two different days (1-week interval). All dogs were sedated with a combination of butorphanol (0.2 mg/kg) and midazolam (0.1 mg/kg) prior to CEUS. The contrast agent (Sonazoid®) was administered using the intravenous bolus method (0.01 ml/kg) for imaging of the duodenum. Time-intensity curves (TIC) were created by drawing multiple regions of interest (ROIs) in the duodenal mucosa, and perfusion parameters, including the time-to-peak (TTP), peak intensity (PI), area under the curve (AUC), and wash-in and wash-out rates (WiR and WoR, respectively), were generated. Intraday and interday coefficients of variation (CVs) for TTP, PI, AUC, WiR and WoR were <25% (range, 2.27-23.41%), which indicated that CEUS was feasible for assessing duodenal perfusion in healthy sedated dogs. A further study of CEUS in dogs with chronic intestinal disorders is necessary to evaluate its clinical applicability.
  • Khoirun Nisa, Sue Yee Lim, Masayoshi Shinohara, Noriyuki Nagata, Kazuyoshi Sasaoka, Angkhana Dermlim, Rommaneeya Leela-Arporn, Tomoya Morita, Nozomu Yokoyama, Tatsuyuki Osuga, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Hiroshi Ohta, Mitsuyoshi Takiguchi
    JOURNAL OF VETERINARY MEDICAL SCIENCE 79 9 1585 - 1590 2017年09月 [査読有り][通常論文]
     
    Contrast-enhanced ultrasonography (CEUS) with microbubbles as a contrast agent allows the visualization and quantification of tissue perfusion. The assessment of canine intestinal perfusion by quantitative CEUS may provide valuable information for diagnosing and monitoring chronic intestinal disorders. This study aimed to assess the repeatability (intraday variability) and reproducibility (interday variability) of quantitative duodenal CEUS in healthy dogs. Six healthy beagles underwent CEUS three times within one day (4-hr intervals) and on two different days (1-week interval). All dogs were sedated with a combination of butorphanol (0.2 mg/kg) and midazolam (0.1 mg/kg) prior to CEUS. The contrast agent (Sonazoid (R)) was administered using the intravenous bolus method (0.01 ml/kg) for imaging of the duodenum. Time-intensity curves (TIC) were created by drawing multiple regions of interest (ROIs) in the duodenal mucosa, and perfusion parameters, including the time-to-peak (TTP), peak intensity (PI), area under the curve (AUC), and wash-in and wash-out rates (WiR and WoR, respectively), were generated. Intraday and interday coefficients of variation (CVs) for TTP, PI, AUC, WiR and WoR were < 25% (range, 2.27-23.41%), which indicated that CEUS was feasible for assessing duodenal perfusion in healthy sedated dogs. A further study of CEUS in dogs with chronic intestinal disorders is necessary to evaluate its clinical applicability.
  • Yoshida T, Ichikawa N, Koike M, Hirokawa T, Sasaoka K, Machida N, Taguchi M
    Journal of Animal Clinical Medicine 25 4 148 - 152 2016年09月 [査読有り][通常論文]
  • Clinical usefulness of Transcranial Doppler ultrasound in dogs.
    Kazuyoshi Sasaoka
    Japanese Journal of Veterinary Research 61 51 - 52 2013年 [査読無し][通常論文]

講演・口頭発表等

  • 鈴木智裕, 池中良徳, 中山翔太, 水川葉月, 一瀬貴大, 佐々木東, 笹岡一慶, 石塚真由美
    第162回日本獣医学会学術集会 2019年09月 口頭発表(一般)
  • 坂本暁彦, 大田寛, 好井健太朗, 矢吹悠久美, 笹岡一慶, 大菅辰幸, 佐々木東, 森下啓太郎, 滝口満喜
    第162回日本獣医学会学術集会 2019年09月 口頭発表(一般)
  • 井上裕美子, 佐々木東, 池中良徳, 一瀬貴大, 笹岡一慶, 大菅辰幸, 中山翔太, 森下啓太郎, 大田寛, 石塚真由美, 滝口満喜
    第162回日本獣医学会学術集会 2019年09月 口頭発表(一般)
  • 黒田杏子, 大菅辰幸, 笹岡一慶, 森下啓太郎, 佐々木東, 大田寛, 滝口満喜
    第162回日本獣医学会学術集会 2019年09月
  • 笹岡一慶, 森下啓太郎, 細谷謙次, 滝口満喜
    令和元年小動物獣医学会(北海道) 2019年08月 口頭発表(一般)
  • 新井田篤, 大田寛, 笹岡一慶, 細谷謙次, 市居修, 賀川由美子, 大菅辰幸, 佐々木東, 森下啓太郎, 滝口満喜
    令和元年小動物獣医学会(北海道) 2019年08月 口頭発表(一般)
  • 田中啓介, 野見山桂, 水川葉月, 水川葉月, 高口倖暉, 田上瑠美, 横山望, 市居修, 滝口満喜, 笹岡一慶, 中山翔太, 池中良徳, 石塚真由美, 国末達也, 田辺信介
    環境化学討論会要旨集(CD-ROM) 2019年06月
  • 経頭蓋超音波ドプラ法による脳血流評価を行った脳梗塞の犬の1例:脳動脈のダイナミックな血流変化の検出.  [通常講演]
    笹岡 一慶, 大田 寛, 石塚 友人, 大菅 辰幸, 森下 啓太郎, 佐々木 東, 滝口 満喜
    第15回日本獣医内科学アカデミー学術大会 2019年02月 口頭発表(一般) 横浜
  • 一般診療エリアにおける院内感染対策:手術部位感染(SSI)対策を極める!〜院内感染症対策と外科医にできる工夫〜  [招待講演]
    笹岡 一慶
    日本獣医麻酔外科学会北海道地区講習会 2019年02月 公開講演,セミナー,チュートリアル,講習,講義等
  • 笹岡一慶, 大田寛, 石塚友人, 大菅辰幸, 立花由莉加, 森下啓太郎, 佐々木東, 滝口満喜
    平成30年度小動物獣医学会(北海道) 2018年09月 口頭発表(一般) 札幌
  • 大村侑己, 大田寛, 小林篤史, 笹岡一慶, 道下明日香, 大菅辰幸, 佐々木東, 森下啓太郎, 滝口満喜
    平成30年度小動物獣医学会(北海道) 2018年09月 口頭発表(一般) 札幌
  • 山田有紗, 笹岡一慶, 大田寛, 立花由莉加, 大菅辰幸, 佐々木東, 森下啓太郎, 滝口満喜
    平成30年度小動物獣医学会(北海道) 2018年09月 口頭発表(一般) 札幌
  • Coming back to the graduate school.  [通常講演]
    Kazuyoshi SASAOKA
    The 6th Sapporo Summer Seminar for One Health (Sapporo) 2018年09月 シンポジウム・ワークショップパネル(指名) Sapporo
  • Effect of cardiac volume loading on left atrial longitudinal strain analysis derived from two-dimensional Speckle Tracking Echocardiography in healthy dogs.  [通常講演]
    Angkhana Dermlim, 中村 健介, 森田 智也, 大菅 辰幸, Khoirun Nisa, Rommaneeya Leela-arporn, 笹岡 一慶, 永田 矩之, 田村 昌大, 佐々木 東, 大田 寛, 森下 啓太郎, 滝口 満喜
    第161回日本獣医学会学術集会 2018年09月 口頭発表(一般) 筑波
  • 佐々木東, 笹岡一慶, 大田寛, 大菅辰幸, 森下啓太郎, 滝口満喜
    日本超音波医学会平成28年度第1回超音波分子診断治療研究会 2018年08月 口頭発表(一般) 札幌
  • Demographic Features, Characteristics and Risk Factors in a Retrospective Study of Hepatocellular Carcinoma in Dogs.  [通常講演]
    Rommaneeya Leela-arporn, Hiroshi Ohta, Noriyuki Nagata, Kazuyoshi Sasaoka, Tatsuyuki Osuga, Keitaro Morishita, Noboru Sasaki, Kensuke Nakamura, Mitsuyoshi Takiguchi
    American College of Veterinary Internal Medicine Forum 2018 2018年06月 ポスター発表 Seattle
  • Trace Elemental Profiles of Serum and Cerebrospinal Fluid in Dogs with Idiopathic Epilepsy.  [通常講演]
    Kazuyoshi Sasaoka, Hiroshi Ohta, Hazuki Mizukawa, Shouta Nakayama, Noboru Sasaki, Keitaro Morishita, Yoshinori Ikenaka, Mayumi Ishizuka, Mitsuyoshi Takiguchi
    American College of Veterinary Internal Medicine Forum 2018 2018年06月 ポスター発表 Seattle
  • てんかん重積状態への対処 ICU管理の1例から.  [通常講演]
    笹岡 一慶
    北海道大学附属動物病院卒後教育セミナー 2018年06月 公開講演,セミナー,チュートリアル,講習,講義等
  • 水川葉月, KHIDKHAN Kraisiri, 高口倖暉, 横山望, 市居修, 滝口満喜, 笹岡一慶, 池中良徳, 池中良徳, 中山翔太, TSEND‐AYUSH Sainnoxoi, 野見山桂, 田辺信介, 石塚真由美
    第27回環境化学討論会 2018年05月 口頭発表(一般) 那覇
  • 田中啓介, 野見山桂, 水川葉月, 高口倖暉, 田上瑠美, 横山望, 市居修, 滝口満喜, 笹岡一慶, 中山翔太, 池中良徳, 石塚真由美, 国末達也, 田辺信介
    第27回環境化学討論会 2018年05月 口頭発表(一般) 那覇
  • Risk factors for hepatocellular carcinoma in dogs: a retrospective case-control study.  [通常講演]
    Rommaneeya Leela-arporn, Hiroshi Ohta, Noriyuki Nagata, Masahiro Tamura, Kazuyoshi Sasaoka, Angkhana Dermlim, Khoirun Nisa, Tomoya Morita, Tatsuyuki Osuga, Morishita Keitaro, Noboru Sasaki, Mitsuyoshi Takiguchi
    第14回日本獣医内科学アカデミー学術大会 2018年02月 口頭発表(一般) 横浜
  • アドレナリン持続点滴が心原性肺水腫の救急管理に有用であった犬の1例.  [通常講演]
    小島 一輝, 石塚 友人, 笹岡 一慶, 大菅 辰幸, 中村 健介, 滝口 満喜
    第14回日本獣医内科学アカデミー学術大会 2018年02月 口頭発表(一般) 横浜
  • 犬の特発性てんかんにおける血中及び脳脊髄液中微量元素濃度の検討.  [通常講演]
    笹岡 一慶, 大田 寛, 水川 葉月, 中山 翔太, 佐々木 東, 森下 啓太郎, 池中 良徳, 石塚 真由美, 滝口 満喜
    第14回日本獣医内科学アカデミー学術大会 2018年02月 口頭発表(一般) 横浜
  • Relationship between transcranial Doppler ultrasound vascular resistance parameters and intracranial hypertension in clinical dogs.  [通常講演]
    Kazuyoshi SASAOKA, Hiroshi OHTA, Noboru SASAKI, Mitsuyoshi TAKIGUCHI
    Asian Meeting of Animal Medicine Specialties 2017 2017年11月 ポスター発表 Taegu
  • 超音波診断装置を用いた脳圧・発作の診断 −容易に利用できる診断ツールを小動物獣医療から人医療へ−  [通常講演]
    笹岡一慶
    博士課程教育リーディングフォーラム2017 2017年10月 ポスター発表 名古屋
  • Effects of Organohalogen Compounds on Serum Biochemical Profiles in Cats.  [通常講演]
    Kraisiri KHIDKHAN, Hazuki MIZUKAWA, Yoshimori IKENAKA, Shota M, M. NAKAYAMA, Kei NOMIYAMA, Nozomu YOKOYAMA, Kazuyoshi SASAOKA, Osamu ICHII, Mitsuyoshi TAKIGUCHI, Shinsuke TANABE, Mayumi ISHIZUKA
    The 5th Sapporo Summer Seminar for One Health 2017年09月 ポスター発表 Sapporo
  • Elevation of transcranial Doppler ultrasound vascular resistance parameters are associated with intracranial hypertension in dogs with brain diseases.  [通常講演]
    Kazuyoshi SASAOKA, Hiroshi OHTA, Noboru SASAKI, Mitsuyoshi TAKIGUCHI
    The 5th Sapporo Summer Seminar for One Health 2017年09月 ポスター発表 Sapporo
  • Quantitative contrast-enhanced ultrasonography of duodenum in dogs with chronic enteropathy.  [通常講演]
    Khoirun Nisa, 大田 寛, 横山 望, 田村 昌大, 永田 矩之, 笹岡 一慶, Angkhana Dermlim, Rommaneeya Leela-Arporn, 森田 智也, 大菅 辰幸, 佐々木 東, 森下 啓太郎, 滝口 満喜
    第160回日本獣医学会学術集会 2017年09月 口頭発表(一般) 鹿児島
  • 笹岡一慶, 大田寛, 田村昌大, 永田矩之, LEELA‐ARPORN Rommaneeya, DERMLIM Angkhana, KHOIRUN Nisa, 森田智也, 佐々木東, 森下啓太郎, 滝口満喜
    第160回日本獣医学会学術集会 2017年09月 口頭発表(一般) 鹿児島
  • 奥朋哉, 大田寛, 田村昌大, 永田矩之, 笹岡一慶, LEELA‐ARPORN Rommaneeya, DERMLIM Angkhana, NISA Khoirun, 森田智也, 大菅辰幸, 佐々木東, 森下啓太郎, 滝口満喜
    第160回日本獣医学会学術集会 2017年09月 口頭発表(一般) 鹿児島
  • 永田矩之, 大田寛, 横山望, 田村昌大, 笹岡一慶, LEELA‐ARPORN Rommaneeya, DERMLIM Angkhana, NISA Khoirun, 森田智也, 大菅辰幸, 佐々木東, 森下啓太郎, 滝口満喜
    第160回日本獣医学会学術集会 2017年09月 口頭発表(一般) 鹿児島
  • 水川葉月, 野見山桂, 池中良徳, 池中良徳, 中山翔太, SAENGTIENCHAI Aksorn, SAINNOXOI Tsendayush, 横山望, 笹岡一慶, 市居修, KHIDKHAN Kraisiri, 高居名菜, 滝口満喜, 田辺信介, 石塚真由美
    第26回環境化学討論会 2017年06月 口頭発表(一般) 静岡
  • 犬における大脳白質病変の臨床的意義に関する検討: 高齢犬の側脳室周囲高信号は症状に関連するか?  [通常講演]
    笹岡 一慶, 大田 寛, 華園 究, 佐々木 東, 森下 啓太郎, 中村 健介, 滝口 満喜
    第13回日本獣医内科学アカデミー学術大会 2017年02月 口頭発表(一般) 横浜
  • 経頭蓋超音波ドプラ法を用いた犬の非侵襲的脳圧亢進診断.  [通常講演]
    笹岡 一慶, 大田 寛, 佐々木 東, 滝口 満喜
    北海道大学第3回部局横断シンポジウム 2017年01月 ポスター発表 札幌
  • 長谷川純也, 大田寛, 横山望, 笹岡一慶, NISA Khoirun, 森田智也, 大菅辰幸, 佐々木東, 森下啓太郎, 中村健介, 滝口満喜
    第159回日本獣医学会学術集会 2016年08月 口頭発表(一般) 藤沢
  • 吉田智彦, 市川直紀, 小池仁彦, 笹岡一慶, 町田登, 田口正行
    第36回動物臨床医学会 2015年11月 口頭発表(一般) 大阪
  • 吉田智彦, 市川直紀, 小池仁彦, 笹岡一慶, 町田登, 田口正行
    第35回動物臨床医学会 2014年11月 口頭発表(一般) 大阪
  • 消化管にクリプトコッカス病変が認められた猫の1例.  [通常講演]
    田口 正行, 市川 直紀, 小池 仁彦, 吉田 智彦, 笹岡 一慶
    第23回中部小動物臨床研究発表会 2014年10月 口頭発表(一般) 名古屋
  • 吉田智彦, 市川直紀, 小池仁彦, 笹岡一慶, 田口正行
    第34回動物臨床医学会 2013年11月 口頭発表(一般) 大阪
  • 笹岡一慶, 市川直紀, 小池仁彦, 吉田智彦, 田口正行
    第34回動物臨床医学会 2013年11月 口頭発表(一般) 大阪
  • 経頭蓋超音波ドプラ法の臨床的有用性に関する研究.  [通常講演]
    笹岡 一慶, 中村 健介, 森下 啓太郎, 大菅 辰幸, Lim Sue Yee, 横山 望, 大田 寛, 山_ 真大, 滝口 満喜
    第9回日本獣医内科学アカデミー学術大会 2013年02月 口頭発表(一般) 横浜
  • 笹岡一慶, 中村健介, 森下啓太郎, 大菅辰幸, LIM Sue Yee, 大田寛, 山崎真大, 滝口満喜
    第51回日本獣医画像診断学会 2012年06月 口頭発表(一般) 大宮

作品等

その他活動・業績

受賞

  • 2018年03月 2016年度クリニカルニュートリション研究会スカラーシッププログラム 優秀研究アワード
     犬の特発性てんかんにおける血中および脳脊髄液中の微量元素濃度の検討
  • 2017年11月 Asian Meeting of Animal Medicine Specialties 2017 Best Poster Award
     Relationship between transcranial Doppler ultrasound vascular resistance parameters and intracranial hypertension in clinical dogs
  • 2013年02月 第9回日本獣医内科学アカデミー学術大会 学術奨励賞<臨床研究AWARD>
     犬の頭蓋内疾患診断における経頭蓋超音波ドプラ法の有用性の検討
  • 2008年07月 北海道大学 北海道大学新渡戸賞

共同研究・競争的資金等の研究課題

  • 経頭蓋超音波ドプラ法を用いた脳血流評価:発作モニタリングの新規指標の確立へ
    日本学術振興会:特別研究員奨励費
    研究期間 : 2018年04月 -2019年03月 
    代表者 : 笹岡一慶
  • 経頭蓋超音波ドプラ法による犬の脳血流評価:発作モニタリングへの応用の検討
    北海道大学博士課程教育リーディングプログラム「One Healthに貢献する獣医科学グローバルリーダー育成プログラム」:平成29年度リーディングプログラム大学院学生科学研究費
    研究期間 : 2017年08月 -2018年03月 
    代表者 : 笹岡一慶
  • 犬の特発性てんかんにおける血中および脳脊髄液中微量元素濃度の検討
    クリニカルニュートリション研究会:クリニカルニュートリション研究会2016年度スカラーシッププログラム
    研究期間 : 2016年06月 -2017年10月 
    代表者 : 笹岡一慶
  • 経頭蓋超音波ドプラ法による犬の脳血流評価の臨床的有用性に関する研究
    北海道大学博士課程教育リーディングプログラム「One Healthに貢献する獣医科学グローバルリーダー育成プログラム」:平成28年度リーディングプログラム大学院学生科学研究費
    研究期間 : 2016年08月 -2017年03月 
    代表者 : 笹岡一慶


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