Researcher basic information

• PhD, Hokkaido University

• https://researchmap.jp/ebiebi0113?lang=en

• https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201001054175181964
• https://hokmmwlab.org/

• 201001054175181964

• network analysis
• network psychometrics
• 女性のメンタルヘルス
• 月経前症候群
• 産後うつ病
• 更年期障害
• 心身症
• ウイメンズヘルス
• HPVワクチン
• がん予防
• 思春期
• 性教育
• 月経随伴症
• 周産期医学
• 特定妊婦
• 社会的ハイリスク妊婦
• 母乳育児
• 婦人科腫瘍学
• 臨床遺伝学
• 生殖免疫学
• 細胞診断学

• Life Science, Obstetrics and gynecology
• Life Science, Lifelong developmental nursing
• Humanities & Social Sciences, Clinical psychology
• Natural Science, Applied mathematics and statistics
• Life Science, Human pathology

• Bachelor's degree program, Departments of Health Sciences, School of Medicine
• Master's degree program, Graduate School of Health Sciences
• Doctoral (PhD) degree program, Graduate School of Health Sciences

Research activity information

• Jun. 2015, 平成27年度兵庫県産科婦人科学会賞
  The IgG avidity value for the prediction of congenital cytomegalovirus infection in a prospective cohort study
  YASUHIKO EBINA

• Development and Psychometric Testing of the Self-Management Difficulty Scale for Pregnant Nurses
  Marie Hino; Yasuhiko Ebina; Rika Yano
  Pacific Rim International Journal of Nursing Research, 01 Oct. 2025, [Peer-reviewed]
  Scientific journal
• Feasibility and Acceptability of a Deep-Learning-Based Nipple Trauma Assessment System for Postpartum Breastfeeding Support
  Maya Nakamura; Hiroyuki Sugimori; Yasuhiko Ebina
  Healthcare, 22 Aug. 2025, [Peer-reviewed]
  Scientific journal
• Role of Silver Nipple Protectors in Treating Nipple Trauma: A Non-Randomized Comparative Trial.
  Maya Nakamura; Hiroyuki Sugimori; Yoko Asaka; Yasuhiko Ebina
  Journal of human lactation : official journal of International Lactation Consultant Association, 41, 3, 382, 391, Aug. 2025, [Peer-reviewed], [International Magazine]
  English, Scientific journal, BACKGROUND: Breastfeeding is crucial for infant health, but nipple trauma remains a common challenge. In particular, nipple trauma can lead to the onset of mastitis and psychological distress for mothers. Silver nipple protectors have been suggested to alleviate this issue, but detailed research is needed. RESEARCH AIM: This study aims to clarify the effectiveness of silver nipple protectors in treating nipple trauma in Japanese women. METHODS: A non-randomized comparative trial compared 47 participants (94 nipples) using silver nipple protectors with a control group of 50 participants (100 nipples) from historical data. The assessment included chronological changes in nipple condition, level of nipple pain, and safety, among other factors. Data collection spanned from 2023 to 2024. RESULTS: The group using silver protectors experienced fewer instances of severe nipple trauma and showed a higher frequency of healing patterns. Many of these patterns involved a transition from mild erythema or swelling toward a healing state. Specifically, the level of nipple pain on the 4th postpartum day was significantly lower. No safety issues from the use of silver protectors were noted. CONCLUSION: This study suggests that silver nipple protectors may prevent the occurrence of severe nipple trauma and are safe and beneficial for Japanese women. Future research should focus on the mechanism of silver protectors, their long-term effects, regional differences, practical challenges for implementation, and comparisons with other common treatments.
• Stability and variability of Edinburgh Postnatal Depression Scale networks among postpartum women: Insights from the Japan Environment and Children's Study.
  Yasuhiko Ebina; Sachiko Ito; Takeshi Yamaguchi; Hiroyoshi Iwata; Reiko Kishi
  Journal of affective disorders, 391, 119992, 119992, 31 Jul. 2025, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
  English, Scientific journal, BACKGROUND: This study aimed to clarify the network structure of the Edinburgh Postnatal Depression Scale (EPDS) in postpartum women using data from the Japan Environment and Children's Study (JECS), a large-scale nationwide birth cohort. METHODS: Network analysis was performed on EPDS data from 89,151 participants at 1 and 6 months postpartum. Gaussian graphical models (GGM) were employed to estimate the direct relationships between EPDS items; predictability measures were used to assess the degree of variance in each item that could be explained by the network. Subgroup analyses were conducted for groups with high (≥9) and low (<9) EPDS scores based on the Japanese cutoff for postpartum depression screening. RESULTS: The EPDS network structure was well-preserved from 1 month to 6 months postpartum. In both periods, "Sad" and "Anxious" demonstrated high centrality, playing key roles in the psychological network. Strong associations between "Hard to sleep" and "Self-harm" were observed in the high-score group at 1 month postpartum, but not at 6 months. Overall predictability was lower in the high-score group, suggesting greater involvement of external factors such as social support, economic conditions, and childcare burden. CONCLUSIONS: This study provides the first insights into the EPDS network structure among postpartum women. Anxiety, sadness, and sleep disturbances emerged as key symptoms, underscoring the need for early intervention. Lower predictability in the high-score group suggests the influence of external factors, emphasizing the need for comprehensive support programs. Future research should consider other populations and time points, such as pregnancy and beyond 1 year postpartum.

  
  
• 高等学校における月経教育:実態と教育提供者の困難感
  和高 一希; 蝦名 康彦
  母性衛生, 66, 1, 71, 79, Apr. 2025, [Peer-reviewed], [Corresponding author]
  Scientific journal
• Pregnant nurses' occupational stress and associated factors: A comparative cross-sectional study with other healthcare workers, physical workers, and desk workers.
  Marie Hino; Yasuhiko Ebina; Rika Yano
  Japan journal of nursing science : JJNS, 22, 2, e70000, Apr. 2025, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, AIM: To examine occupational stress levels and associated factors among pregnant nurses through a comparison with pregnant non-nurses. METHODS: This cross-sectional study included 1060 working pregnant women. Participants completed questionnaires including the Brief Job Stress Questionnaire, work conditions, obstetric conditions, Sense of Coherence Scale, and self-management behaviors questionnaire. The participants were categorized into four groups: nurses, other healthcare workers, physical workers, and desk workers. Comparisons were made between the four groups and by gestational ages using Dunnett's test and chi-squared test, and associated factors were examined using ordinal logistic regression analysis. RESULTS: Analysis of 847 valid responses showed that the nurse group had a higher occupational stress, higher job demand, and lower job control at any gestational age than the other profession groups. Nurses' occupational stress was associated with factors such as frequent overtime work, fewer break times, lower manager support, and lower prioritizing the fetus. Particularly, fewer break times and lower prioritizing the fetus were nurse-specific associated factors. CONCLUSIONS: The study showed that pregnant nurses are exposed to higher occupational stress throughout the entire pregnancy than other occupations. The stress was related to modifiable factors such as fewer break times and lower prioritizing the fetus. To manage occupational stress, pregnant nurses should avoid overtime, take breaks, and prioritize the fetus in the workplace. Hospital administrators would need to provide work coordination support and consider certain regulations regarding hazardous work restrictions for pregnant nurses. Future cohort studies are required to better understand occupational stress among pregnant nurses.
• Development of Nipple Trauma Evaluation System With Deep Learning
  Maya Nakamura; Hiroyuki Sugimori; Yasuhiko Ebina
  Journal of Human Lactation, Feb. 2025, [Peer-reviewed]
  English, Scientific journal
• Systematic Review on the Efficacy of Moisturizing Therapy in Treating Nipple Trauma and Nipple Pain
  Maya Nakamura; Yunjie Luo; Yasuhiko Ebina
  Journal of Human Lactation, Feb. 2025, [Peer-reviewed]
  English, Scientific journal
• 不妊治療中の就労女性のストレス状況,対処法および求めているメンタルヘルスケア
  生田 寿波; 蝦名 康彦
  母性衛生, 65, 4, 454, 461, Jan. 2025, [Peer-reviewed], [Corresponding author]
  Scientific journal
• 統合失調症をもつ女性に対する産前・産後の精神科訪問看護 ケア内容の実態と看護職の困難感
  金内 里美; 蝦名 康彦
  母性衛生, 65, 4, 436, 444, Jan. 2025, [Peer-reviewed], [Corresponding author]
  Scientific journal
• The Effects of Active Stretching Exercise on Mood and Autonomic Modulation in Middle-Aged Women
  Miho Komatsuzaki; Yuta Koshino; Tomoya Ishida; Satoshi Kasahara; Fiorella Apolo Soria; Yasuhiko Ebina; Harukazu Tohyama; Mina Samukawa
  Women's Health Reports, 5, 1, 680, 688, Mary Ann Liebert Inc, 16 Sep. 2024, [Peer-reviewed]
  Scientific journal
• Effectiveness of moisturising therapy in treating nipple trauma: a systematic review protocol.
  Maya Nakamura; Yunjie Luo; Yasuhiko Ebina
  BMJ open, 14, 9, e083389, 13 Sep. 2024, [Peer-reviewed], [International Magazine]
  English, Scientific journal, INTRODUCTION: Breastfeeding is crucial in infant nutrition and bonding, recommended for at least 6 months and up to 2 years postpartum, providing health benefits for both infants and mothers. However, nipple trauma is common among lactating mothers. Moisturising therapies, such as hydrogel application, aim to promote the healing of nipple wounds. Despite various interventions proposed, comprehensive reviews evaluating the efficacy of moisturising therapies for nipple trauma are lacking. This review aims to appraise the effectiveness of moisturising therapy, particularly tailored for nipple trauma in lactating women. METHODS AND ANALYSIS: This systematic review protocol adheres to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines and is registered in the International Prospective Register of Systematic Reviews. The focus will be on both randomised and non-randomised controlled trials addressing the treatment of nipple trauma in lactating women. In this context, 'moisturising therapy' is categorised as a non-pharmacological intervention applied directly to the nipple, excluding treatments for bacterial or fungal infections. The primary outcomes will include measures of the healing efficiency of nipple trauma and reduction in nipple pain. Searches will be conducted without date restrictions across multiple databases, including PubMed, CINAHL, the Cochrane Library, Web of Science, CiNii Research and Ichushi-Web, in addition to exploration of grey literature. Two independent reviewers will manage all stages of the review process, under the supervision of a third reviewer. Data extraction will encompass participant demographics, study methodologies, sample specifics and measured outcomes. Quality assessment will be conducted using the Joanna Briggs Institute Appraisal Checklist Tools. ETHICS AND DISSEMINATION: Ethics approval is not required for this study. The findings of this review will be disseminated through academic publications, detailed reports and presentations at relevant conferences. PROSPERO REGISTRATION NUMBER: CRD42023481761.
• Effect of an Internet-based mental health promotion intervention among immigrant Chinese women: A quasi-experimental study
  Yunjie Luo; Yasuhiko Ebina; Yoko Sato
  SSM - Population Health, 26, 101686, 101686, Elsevier BV, Jun. 2024, [Peer-reviewed]
  Scientific journal
• 統合失調症をもつ妊産褥婦への支援方法に関する文献検討
  金内 里美; 蝦名 康彦
  母性衛生, 64, 4, 756, 762, (公社)日本母性衛生学会, Jan. 2024, [Peer-reviewed], [Corresponding author]
  Japanese
• 自己採取HPV検査の導入が女子大学生の子宮頸がん検診における受診意識に及ぼす影響
  藤澤 玲花; 竹内 瑞季; 蝦名 康彦
  看護総合科学研究会誌, 21, 1, 3, 10, 看護総合科学研究会, Dec. 2023, [Peer-reviewed], [Corresponding author]
  Japanese
• Toward Better Care of Rare Ovarian Tumors
  Yasuhiko Ebina
  Clinical and Experimental Obstetrics & Gynecology, 50, 9, 186, 186, IMR Press, 19 Sep. 2023, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal

  
  Preprint
• 妊産婦のメンタルヘルス支援における多職種連携に関する文献検討
  小林 后; 蝦名 康彦
  母性衛生, 64, 1, 196, 203, (公社)日本母性衛生学会, Apr. 2023, [Peer-reviewed], [Corresponding author]
  Japanese
• 産後うつ病に対する妊娠期の予防的介入の実施状況と実施に影響を与える因子に関する検討
  竹内 瑞季; 蝦名 康彦
  母性衛生, 63, 4, 747, 757, (公社)日本母性衛生学会, Jan. 2023, [Peer-reviewed], [Corresponding author]
  Japanese
• Promotion of Parenting and Mental Health Needs among Chinese Women Living in Japan: A Qualitative Study.
  Yunjie Luo; Yoko Sato; Tianyue Zhai; Hiromi Kagamiyama; Yasuhiko Ebina
  International journal of environmental research and public health, 19, 20, 19 Oct. 2022, [Peer-reviewed], [Corresponding author], [International Magazine]
  English, Scientific journal, Chinese women raising children in Japan tend to experience high parenting stress and poor mental well-being. However, their specific parenting and mental health promotion needs remain unknown. This study aimed to explore the parenting and mental health promotion needs of Chinese women living in Japan and provide recommendations to guide interventions. Semi-structured in-depth interviews were conducted. Participants included 15 women aged 28-39 years who were pregnant or rearing a child younger than six years old. Thematic analysis was performed for data analysis. More than half of the participants experienced mental health problems, such as depressive symptoms and child-rearing stress. Four themes relating to their needs were identified: concrete support, information provision, caring and understanding, and social network building. Information provision and social network building should be emphasized as practical social support mechanisms to improve these women's mental health. Furthermore, a mental health promotion intervention should be developed to address this vulnerable population's needs. Healthcare providers and public health workers should help improve the social support systems of Chinese women in Japan to prevent mental health problems. Potential transcultural education can, arguably, help healthcare providers better understand transcultural care.
• Impact of adjuvant chemotherapy on the overall survival of patients with resectable bulky small cell neuroendocrine cervical cancer: a JSGO-JSOG joint study.
  Manabu Seino; Satoru Nagase; Tsuyoshi Ohta; Wataru Yamagami; Yasuhiko Ebina; Yoichi Kobayashi; Tsutomu Tabata; Masanori Kaneuchi; Takayuki Enomoto; Mikio Mikami
  Journal of gynecologic oncology, 34, 1, e4, 29 Sep. 2022, [Peer-reviewed], [International Magazine]
  English, Scientific journal, OBJECTIVE: The aim of this study was to review the clinicopathological characteristics of small cell neuroendocrine cervical cancer (SCNEC) and to identify the optimal treatment. METHODS: The Japanese Society of Gynecologic Oncology conducted a retrospective cohort study of SCNECs enrolled in the Gynecological Tumor Registry of the Japan Society of Obstetrics and Gynecology between 2004 and 2015. All cases were modified and unified by International Federation of Gynecology and Obstetrics 2008 (Union for International Cancer Control 7th edition). RESULTS: There were 822 registered patients diagnosed with SCNEC from 2004 to 2015 which comprised 1.1% (822/73,698) of all uterine cervical cancer cases. Rates of lymph-node and distant metastasis were significantly higher in T1b2 (38.9% and 13.7%, respectively) than T1b1 (14.2% and 4.4%, respectively) (p<0.01). In IB2 and T1bN1M0 SCNEC, the 5-year survival rate with surgery followed by chemotherapy was significantly higher than that with surgery followed by radiation therapy/concurrent chemoradiation therapy (p<0.01). CONCLUSION: SNCEC tumors >4 cm in size had greater rates of lymph-node and distant metastasis when compared with tumors ≤4 cm. Adjuvant chemotherapy, rather than radiotherapy, may improve prognosis after surgery in T1bN1M0 SCNEC.
• 特定妊婦の特徴 夜間産婦人科救急相談電話における432件の分析
  大川 加奈; 蝦名 康彦
  母性衛生, 63, 2, 474, 482, (公社)日本母性衛生学会, Jul. 2022, [Peer-reviewed], [Corresponding author]
  Japanese
• Interventions to improve immigrant women's mental health: A systematic review
  Yunjie Luo; Yasuhiko Ebina; Hiromi Kagamiyama; Yoko Sato
  Journal of Clinical Nursing, Wiley, 02 Jun. 2022, [Peer-reviewed]
  English, Scientific journal
• 高校生の妊娠成立後の受診行動に関連する因子
  吉田 ひかる; 蝦名 康彦
  母性衛生, 63, 1, 43, 52, (公社)日本母性衛生学会, Apr. 2022, [Peer-reviewed], [Corresponding author]
  Japanese
• 妊婦のやせ願望の要因と出生体重の関連
  水口 実咲; 蝦名 康彦
  母性衛生, 63, 1, 53, 62, (公社)日本母性衛生学会, Apr. 2022, [Peer-reviewed], [Corresponding author]
  Japanese
• わが国の産後うつ病に対する妊娠期の予防的介入についての文献検討
  竹内 瑞季; 蝦名 康彦
  母性衛生, 63, 1, 165, 179, (公社)日本母性衛生学会, Apr. 2022, [Peer-reviewed], [Corresponding author]
  Japanese
• Significance of histology and nodal status on the survival of women with early-stage cervical cancer: validation of the 2018 FIGO cervical cancer staging system.
  Hiroko Machida; Koji Matsuo; Yoichi Kobayashi; Mai Momomura; Fumiaki Takahashi; Tsutomu Tabata; Eiji Kondo; Wataru Yamagami; Yasuhiko Ebina; Masanori Kaneuchi; Satoru Nagase; Mikio Mikami
  Journal of gynecologic oncology, 33, 3, e26, 03 Feb. 2022, [Peer-reviewed], [International Magazine]
  English, Scientific journal, OBJECTIVE: To assess the efficacy of the FIGO 2018 classification system for nodal-specific classifications for early-stage cervical cancer; specifically, to examine the impact of nodal metastasis on survival and the effect of postoperative treatments, according to histological subtypes. METHODS: This society-based retrospective observational study in Japan examined 16,539 women with the 2009 FIGO stage IB1 cervical cancer who underwent primary surgical treatment from 2004 to 2015. Associations of cause-specific survival (CSS) with nodal metastasis and postoperative adjuvant therapy were examined according to histology type (squamous cell carcinoma [SCC], n=10,315; and non-SCC, n=6,224). RESULTS: The nodal metastasis rate for SCC was higher than that for non-SCC (10.7% vs. 8.3%, p<0.001). In multivariable analysis, the impact of nodal metastasis on CSS was greater for non-SCC tumors (adjusted-hazard ratio [HR], 3.11; 95% confidence interval [CI], 2.40-4.02) than for SCC tumors (adjusted-HR, 2.20; 95% CI, 1.70-2.84; p<0.001). Propensity score matching analysis showed significantly lower CSS rates for women with pelvic nodal metastasis from non-SCC tumors than from SCC tumors (5-year CSS rate, 75.4% vs. 90.3%, p<0.001). The CSS rates for women with nodal metastasis in SCC histology were similar between the postoperative concurrent chemoradiotherapy/radiotherapy and chemotherapy groups (89.2% vs. 86.1%, p=0.42), whereas those in non-SCC histology who received postoperative chemotherapy improved the CSS (74.1% vs. 67.7%, p=0.043). CONCLUSION: The node-specific staging system in the 2018 FIGO cervical cancer classification is applicable to both non-SCC tumors and SCC tumors; however, the prognostic significance of nodal metastases and efficacy of postoperative therapies vary according to histology.
• Impact of the COVID-19 pandemic on the policies and practices of delivery facilities in Japan
  Yasuhiko Ebina; Mizuki Takeuchi; Maya Nakamura
  Clinical and Experimental Obstetrics & Gynecology, 49, 1, 1, 1, IMR Press, 10 Jan. 2022, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal, Background: To clarify the impact of the COVID-19 pandemic on the policies and practices of delivery facilities in Japan from April 2020 to March 2021. Methods: We conducted an online survey of midwives working in obstetric wards nationwide between May 15, 2021, and July 31, 2021. We analyzed the 376 valid responses. Results: With the COVID-19 pandemic, most facilities have barred or partially restricted families and other visitors from being present (patient companions) in outpatient clinics, prenatal classes, during delivery, inpatient care, and inpatient visits. These changes were implemented nationwide, regardless of regional differences in the pandemic state of COVID-19. Meanwhile, by facility classification, prenatal classes, companion at birth, and inpatient visits were more likely to be canceled at perinatal centers than at clinics. The acceptance of “satogaeri deliveries” (a custom in Japan where pregnant women return to their natal homes for labor and childbirth) was partially restricted to about 40% of facilities, although this rate was lower in the four Kanto prefectures (Tokyo, Kanagawa, Saitama, and Chiba). Conclusions: With the COVID-19 pandemic, the differences in Japan’s policies and practices of delivery facilities were attributed more to the role played by facilities in the regional perinatal system than to regional pandemic status.
• Comparison of treatment outcomes of surgery and radiotherapy, including concurrent chemoradiotherapy for stage Ib2-IIb cervical adenocarcinoma patients: a retrospective study.
  Eiji Kondo; Kenta Yoshida; Tsutomu Tabata; Yoichi Kobayashi; Wataru Yamagami; Yasuhiko Ebina; Masanori Kaneuchi; Satoru Nagase; Hiroko Machida; Mikio Mikami
  Journal of gynecologic oncology, 33, 2, e14, 06 Dec. 2021, [Peer-reviewed], [International Magazine]
  English, Scientific journal, OBJECTIVE: The study compared the treatment outcomes of surgery versus radiotherapy, including concurrent chemoradiotherapy, in stage Ib2-IIb cervical adenocarcinoma patients in Japan. METHODS: Of 57,470 patients diagnosed with stage I-IV cervical cancer from January 2001-December 2011, 1,932 patients with stage Ib2-IIb cervical adenocarcinoma were initially treated by surgery or radiotherapy. The primary endpoint was 5-year overall survival (OS) in all and 614 propensity score-matched (PSM) patients (307 per group). We compared OS and prognosis factors based on age, primary stage, and treatment arm. RESULTS: In Japan, >80% (n=1,573) of stage Ib2-IIb cervical adenocarcinoma patients underwent surgery. The 5-year OS of surgery vs. radiotherapy groups were 82.1% (n=704) vs. 79.7% (n=59) (hazard ratio [HR]=1.494; 95% confidence interval [CI]=0.826-2.702; p=0.181) for stage Ib2, 76.6% (n=239) vs. 66.7% (n=54) (HR=1.679; 95% CI=0.986-2.858; p=0.053) for stage IIa, and 71.1% (n=630) vs. 58.9% (n=246) (HR=1.711; 95% CI=1.341-2.184; p<0.001) for stage IIb. In 614 PSM patients balanced for age and carcinoma stage Ib2-IIb, the 5-year OS of surgery vs. radiation groups was 73.0% (n=307) vs. 65.5% (n=307) (HR=1.394; 95% CI=1.044-1.860; p=0.023). In multivariable analysis, age (HR=1.293; 95% CI=1.045-1.601; p=0.018), treatment arm, radiotherapy (HR=1.556; 95% CI=1.253-1.933; p<0.001), and stage IIb (HR=1.783; 95% CI=1.443-2.203; p=0.018) were independent prognosis factors for 5-year OS in stage Ib2-IIb adenocarcinoma patients. CONCLUSION: Age (>65 years), treatment arm (radiotherapy), and stage IIb significantly affect OS in cervical adenocarcinoma patients. Surgery may be considered for <65-year-old patients with stage IIb adenocarcinoma.
• Clinicopathological characteristics and prognostic factors of ovarian granulosa cell tumors: A JSGO-JSOG joint study.
  Yasuhiko Ebina; Wataru Yamagami; Yoichi Kobayashi; Tsutomu Tabata; Masanori Kaneuchi; Satoru Nagase; Takayuki Enomoto; Mikio Mikami
  Gynecologic oncology, 25 Aug. 2021, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
  English, Scientific journal, OBJECTIVES: The aim of this study was to elucidate the clinicopathological features of ovarian granulosa cell tumors (GCTs) and to identify the prognostic factors. METHODS: The Japanese Society of Gynecologic Oncology (JSGO) conducted an observational retrospective cohort study of women with GCTs enrolled in the Gynecological Tumor Registry of the Japan Society of Obstetrics and Gynecology (JSOG) between 2002 and 2015. Clinicopathological features, including lymph node metastasis, were evaluated. In addition, we performed a prognostic analysis of patients between 2002 and 2011 for whom survival data were available. Kaplan-Meier and multivariate Cox proportional hazards analyses were performed. RESULTS: We identified 1426 patients with GCTs. Of the 222 patients who underwent lymph node dissection, 10 (4.5%) had lymph node metastasis. The incidence of lymph node metastasis in patients with pT1, pT2, and pT3 was 2.1%, 13.3%, and 26.7%, respectively (p < 0.001). Prognostic analysis was performed on 674 patients. In the multivariate Cox regression analysis, residual disease after initial surgery (hazard ratio (HR) = 10.39, 95% confidence interval (CI) = 3.15-34.29) and lymph node metastasis (HR = 5.58, 95% CI = 1.62-19.19) were independent risk factors for cancer-specific survival. CONCLUSIONS: In the initial surgery for GCTs, lymph node dissection can be omitted if the operative finding is pT1. In cases of pT2 or higher, lymph node dissection should be considered. Debulking is critical for achieving no gross residual tumor at the end of the surgery.
• A retrospective study for investigating the outcomes of endometrial cancer treated with radiotherapy.
  Kensuke Sakai; Wataru Yamagami; Hiroko Machida; Yasuhiko Ebina; Yoichi Kobayashi; Tsutomu Tabata; Masanori Kaneuchi; Satoru Nagase; Takayuki Enomoto; Daisuke Aoki; Mikio Mikami
  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 156, 2, 262, 269, 29 Apr. 2021, [Peer-reviewed], [International Magazine]
  English, Scientific journal, OBJECTIVE: To clarify the role of radiotherapy for endometrial cancer. METHODS: Data were analyzed for 39 247 patients with endometrial cancer registered with the Gynecologic Cancer Registry of the Japan Society of Obstetrics and Gynecology from 2004 to 2011. RESULTS: The rates of 5-year overall survival (5y-OS) in the radiotherapy and surgery groups were 53.6% and 94.5% in stage I or II, and 15.5% and 67.5% in stage III or IV, respectively. The prognosis in the radiotherapy group was significantly poorer than that in the surgery group. In multivariate analysis, age, advanced stage, histological type, risk of recurrence, and initial radiotherapy were independent prognostic factors. The rates of 5y-OS with no adjuvant therapy, adjuvant chemotherapy, and adjuvant radiotherapy were 95.3%, 92.9%, and 87.1% for stage I or II, respectively, with significant differences among all groups (P < 0.001), and 60.0%, 70.4%, and 55.5% for stage III or IV, respectively, with significant differences of adjuvant chemotherapy with no adjuvant therapy (P < 0.001) and with adjuvant radiotherapy (P < 0.001). In multivariate analysis, age, advanced stage, histological type, lymphadenectomy, and adjuvant radiotherapy were independent prognostic factors. CONCLUSION: Patients treated with radiotherapy had a significantly poorer prognosis and the appropriate indication of radiotherapy for endometrial cancer requires further study.
• Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort study.
  Emi Hirayama; Yasuhiko Ebina; Kei Kato; Kinuko Akabane-Nakagawa; Kazuhiko Okuyama
  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 20 Jan. 2021, [Peer-reviewed], [Corresponding author], [International Magazine]
  English, Scientific journal, OBJECTIVE: To determine the association between cervical polyps in early pregnancy and late abortion and spontaneous preterm birth (SPTB). We also aimed to explore the relationship between cervical polyps and cervical insufficiency in the second trimester. METHODS: We conducted a retrospective cohort study of 2941 singleton pregnant women between January 2010 and December 2015. The frequency of late abortion and SPTB (before 28, 34, or 37 weeks of pregnancy) was compared between the two groups of 142 (4.8%) patients who had cervical polyps early in the pregnancy (P group) and 2799 who did not (non-P group). Multivariate analysis was performed to identify risk factors for late abortion and SPTB. RESULTS: The incidence of late abortion and SPTB was significantly higher in the P group than in the non-P group. Cervical polyps in early pregnancy were selected as independent risk factors for late abortion and SPTB before 28, 34, or 37 weeks of pregnancy. The P group had a significantly higher rate of cases requiring therapeutic cervical cerclage than the non-P group. CONCLUSION: Cervical polyps in early pregnancy are risk factors for late abortion and SPTB. They are also associated with the occurrence of cervical insufficiency.
• Impact of lymphadenectomy on the treatment of endometrial cancer using data from the JSOG cancer registry.
  Keiko Saotome; Wataru Yamagami; Hiroko Machida; Yasuhiko Ebina; Yoichi Kobayashi; Tsutomu Tabata; Masanori Kaneuchi; Satoru Nagase; Takayuki Enomoto; Daisuke Aoki; Mikio Mikami
  Obstetrics & gynecology science, 64, 1, 80, 89, Jan. 2021, [Peer-reviewed], [International Magazine]
  English, Scientific journal, OBJECTIVE: Regional lymph node (LN) dissection is a standard surgical procedure for endometrial cancer, but there is currently no clear consensus on its therapeutic significance. We aimed to determine the impact of regional LN dissection on the outcome of endometrial cancer. METHODS: Study subjects comprised 36,813 patients who were registered in the gynecological tumor registry of the Japan Society of Obstetrics and Gynecology, had undergone initial surgery for endometrial cancer between 2004 and 2011, and whose clinicopathological factors and prognosis were appropriate for our investigation. The following clinicopathological factors were obtained from the registry: age, surgical stage classification, Union for International Cancer Control tumor, node, metastasis classification, histological type, histological differentiation, presence or absence of LN dissection, and postoperative treatment. We retrospectively analyzed the clinicopathological factors and therapeutic outcomes for patients with endometrial cancer. RESULTS: Analysis of all subjects showed that the group that underwent LN dissection had a significantly better overall survival than the group that did not undergo dissection. Analysis based on stage showed similar results across groups, except for stage Ia. Analysis based on stage and histological type showed similar results across groups, except for stage Ia endometrial carcinoma G1 or Ia G2. Multivariate analysis of prognostic factors indicated that LN dissection is an independent prognostic factor and that it has a greater impact on prognosis than adjuvant chemotherapy. CONCLUSION: Despite the limitations of a retrospective study with some biases, the results suggest that LN dissection in endometrial cancer has a prognostic effect.
• Proposal of a Two-Tier System in Grouping Adenocarcinoma of the Uterine Cervix.
  Hiroko Machida; Koji Matsuo; Shinya Matsuzaki; Wataru Yamagami; Yasuhiko Ebina; Yoichi Kobayashi; Tsutomu Tabata; Masanori Kaneuchi; Satoru Nagase; Takayuki Enomoto; Mikio Mikami
  Cancers, 12, 5, 15 May 2020, [Peer-reviewed], [International Magazine]
  English, Scientific journal, (1) Background: This study examined the use of a two-tier system in grouping cervical adenocarcinoma for survival discrimination. (2) Methods: A nationwide retrospective observational cohort study was conducted using the Japan Society of Gynecologic Oncology tumor registry database from 2001 to 2015 (n = 86,754). Adenocarcinoma subtypes were grouped as type 1 (endocervical usual type and endometrioid) or type 2 (serous, clear, mucinous, and not otherwise specified), based on their relative survival compared with that of squamous tumors. (3) Results: The majority of the adenocarcinoma cases were type 1 (n = 10,121) versus type 2 tumors (n = 5157). Type 2 tumors were more likely to be old and have stage IV disease than those with squamous tumors. The number of type 2 tumors increased from 2001 to 2014 (106.1% relative increase, p < 0.001). Type 2 tumors had disproportionally poorer survival compared to other types (5-year survival rates: 68.9% for type 2, 75.4% for type 1, and 78.0% for squamous; p < 0.001). On multivariate analysis, type 2 tumors remained an independent prognostic factor associated with decreased survival compared with squamous (adjusted hazard ratio 2.00, 95% CI 1.84-2.15, p < 0.001). (4) Conclusion: The survival of cervical adenocarcinoma varies largely across the histological subtypes, and the proposed two-tier grouping may be useful for survival discrimination.
• Intraoperative Capsule Rupture, Postoperative Chemotherapy, and Survival of Women With Stage I Epithelial Ovarian Cancer.
  Koji Matsuo; Hiroko Machida; Wataru Yamagami; Yasuhiko Ebina; Yoichi Kobayashi; Tsutomu Tabata; Masanori Kaneuchi; Satoru Nagase; Takayuki Enomoto; Mikio Mikami
  Obstetrics and gynecology, 134, 5, 1017, 1026, Nov. 2019, [Peer-reviewed], [International Magazine]
  English, Scientific journal, OBJECTIVE: To examine the incidence and prognostic effects of intraoperative capsule rupture and to assess the effectiveness of postoperative chemotherapy for intraoperative tumor rupture in apparent stage I epithelial ovarian cancer. METHODS: This is a society-based retrospective observational study in Japan that examined 15,163 women with stage IA-IC1 epithelial ovarian cancer who underwent primary surgical treatment between 2002 and 2015. Associations between intraoperative capsule rupture and cause-specific survival, and between postoperative chemotherapy and cause-specific survival among intraoperatively ruptured cases were examined by histology type (clear cell n=6,107, endometrioid n=3,910, mucinous n=3,382, and serous n=1,764). RESULTS: Clear cell histology had the highest risk of intraoperative capsule rupture (57.3%), followed by endometrioid (48.8%), serous (41.8%), and mucinous (32.0%) histologies (P<.001). On multivariable analysis, clear cell type exhibited the largest effect of intraoperative capsule rupture on cause-specific survival (adjusted hazard ratio [HR] 1.99, 95% CI 1.45-2.75), followed by serous (adjusted HR, 1.61, 95% CI 0.84-3.11), mucinous (adjusted HR 1.28, 95% CI 0.79-2.09), and endometrioid (adjusted HR, 1.14, 95% CI 0.64-2.01) tumors. Postoperative chemotherapy for intraoperatively ruptured cases did not improve cause-specific survival in any histologic types in multivariable analysis: clear cell, adjusted HR 0.86, 95% CI 0.56-1.31; serous, adjusted HR 1.08, 95% CI 0.42-2.74; mucinous, adjusted HR 1.11, 95% CI 0.55-2.27; and endometrioid, adjusted HR 2.81, 95% CI 0.85-9.30 (all, P>.05). In the cohort-level analysis of ruptured cases (n=7,227), postoperative chemotherapy use has significantly decreased in mucinous (16.3% relative decrease), endometrioid (13.1% relative decrease), and clear cell (9.3% relative decrease) (all, P<.05); but, the cohort-level 5-year cause-specific survival rate did not change over time (all, P>.05). CONCLUSION: Among apparent stage I epithelial ovarian cancer, the clear cell type possesses a disproportionally high risk of capsule rupture during adnexectomy and is associated with the most adverse effect on survival. A decrease in the use of postoperative chemotherapy for intraoperatively ruptured cases in Japan is likely the result of increasing awareness of the absence of survival benefits.
• Clinical factors associated with pregnancy outcome in women with recurrent pregnancy loss.
  Maho Miyaji; Masashi Deguchi; Kenji Tanimura; Yuki Sasagawa; Mayumi Morizane; Yasuhiko Ebina; Hideto Yamada
  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 35, 10, 913, 918, Oct. 2019, [Peer-reviewed], [International Magazine]
  English, Scientific journal, The aim of this prospective cohort study was to evaluate clinical factors associated with pregnancy outcomes in women with recurrent pregnancy loss (RPL). Women with a history of two or more pregnancy losses underwent workups for clinical factors of RPL and their pregnancies were followed-up with informed consent. Two hundred eleven (81.5%) of 259 women with RPL became pregnant. The multivariable analyses demonstrated that age (p < .01, OR 0.9, 95%CI 0.97-0.83), uterine abnormality (p < .05, OR 0.3, 95%CI 0.11-0.8), and protein C (PC) deficiency (p < .01, OR 0.14, 95%CI 0.03-0.6) were independent factors for becoming pregnancy in women with RPL. The number of previous pregnancy loss (p < .01, OR 0.57, 95%CI 0.43-0.75) and natural killer (NK) cell activity ≥33% (p < .01, OR 0.31, 95%CI 0.13-0.73) were independent factors for live birth in the subsequent pregnancy. Advanced age, the presence of uterine abnormality, and PC deficiency were risk factors for reduced pregnancy rate in women with RPL. Increased number of previous pregnancy loss and high NK cell activity were risk factors for miscarriage in the subsequent pregnancy. These results involve important information and are helpful for clinical practitioners.
• 子宮頸部細胞診ASC-H判定例の臨床的取り扱い 病理組織診断および転帰に関する検討
  今福 仁美; 蝦名 康彦
  日本臨床細胞学会雑誌, 58, 4, 162, 166, (公社)日本臨床細胞学会, Jul. 2019, [Peer-reviewed], [Corresponding author]
  Japanese
• A cohort study of maternal screening for congenital Toxoplasma gondii infection: 12 years' experience.
  Hideto Yamada; Kenji Tanimura; Masashi Deguchi; Shinya Tairaku; Mayumi Morizane; Akiko Uchida; Yasuhiko Ebina; Akira Nishikawa
  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 25, 6, 427, 430, Jun. 2019, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Primary infection with Toxoplasma gondii (T. gondii) during pregnancy may cause congenital infection of the infant. This study evaluated whether screening using IgG avidity and multiplex-nested polymerase chain reaction (PCR) methods was effective for detecting a high-risk pregnancy for congenital T. gondii infection. In a prospective cohort study serum T. gondii IgG avidity was measured in 469 pregnant women who had a positive test for T. gondii antibody plus a positive or equivocal test for IgM. Multiplex-nested PCR for T. gondii DNA on amniotic fluid, maternal blood, and neonatal blood was performed with informed consent. Low (<30%), borderline (30-35%), and high (>35%) IgG avidity indices were found in 104 (22.2%), 30 (6.4%), and 305 (71.4%), respectively. A total of 12 cases had a positive PCR test for amniotic fluids of the prenatal amniocentesis or at birth, or neonatal blood. Seven of the 12 cases were diagnosed as having congenital T. gondii infection, and they had low IgG avidity indices. Congenital T. gondii infection screening using of IgG avidity and multiplex-nested PCR methods for pregnant women with a positive test for T. gondii antibody plus a positive or equivocal test for T. gondii IgM was useful for detecting a high-risk pregnancy and diagnosing congenital T. gondii infection.
• Trends and characteristics of epithelial ovarian cancer in Japan between 2002 and 2015: A JSGO-JSOG joint study.
  Hiroko Machida; Koji Matsuo; Wataru Yamagami; Yasuhiko Ebina; Yoichi Kobayashi; Tsutomu Tabata; Masanori Kanauchi; Satoru Nagase; Takayuki Enomoto; Mikio Mikami
  Gynecologic oncology, 153, 3, 589, 596, Jun. 2019, [Peer-reviewed], [International Magazine]
  English, Scientific journal, OBJECTIVE: To examine the trends of epithelial ovarian cancer histologic subtypes in Japan. METHODS: A nationwide retrospective registry study was performed between 2002 and 2015 (Japan cohort, n = 48,640). Trends were also examined in The Surveillance, Epidemiology, and End Results Program (US cohort, n = 49,936). Time-specific proportional changes of four major histological subtypes (serous, clear cell, endometrioid, and mucinous) were examined. RESULTS: The Japan cohort had more stage I disease (44.1% versus 24.9%) and less stage IV disease (10.0% versus 23.1%) than the US cohort (P < 0.001). The Japan cohort had more non-serous histology, particularly clear cell carcinoma (26.9% versus 8.4%), than the US cohort (P < 0.001). In the Japan cohort, proportion of clear cell carcinoma increased significantly from 23.4% to 29.1% between 2002 and 2010 (P < 0.001). Among stage I disease, clear cell carcinoma increased significantly in the Japan cohort from 32.9% to 40.3% between 2002 and 2015 (P < 0.001), whereas mucinous carcinoma increased significantly in the US cohort from 15.0% to 24.8% (P = 0.01). In 2015, clear cell carcinoma was most common among women aged <50 years from the Japan cohort (30.2%) versus serous carcinoma in the US cohort (50.8%). In the Japan cohort, the peak age was 75 years for serous, 57 for clear cell, and 45 for endometrioid carcinoma (P < 0.001). Mucinous carcinoma decreased until 43 years and increased again after age 73 years (P < 0.001). CONCLUSION: Characteristics of epithelial ovarian cancer in Japan are largely different compared to the US. In Japan, clear cell carcinoma has increased significantly in recent years to account for nearly 30% of epithelial ovarian cancer.
• Neonatal Alloimmune Thrombocytopenia: A Report of Four Cases.
  Mizuki Uenaka; Mayumi Morizane; Kenji Tanimura; Masashi Deguchi; Yasuhiko Ebina; Makoto Hashimoto; Ichiro Morioka; Hideto Yamada
  The Kobe journal of medical sciences, 64, 6, E197-E199, E199, 05 Mar. 2019, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, Antibodies against fetal platelet alloantigens in maternal blood cause neonatal alloimmune thrombocytopenia (NAIT). We encountered four newborns with NAIT from three women. A woman carried anti-human platelet antigen (HPA)-1a antibody, and vaginally delivered a newborn who had subarachnoid hemorrhage and platelet transfusions. She delivered the second newborn by a cesarean section who had no symptom. The second woman carried anti-human leukocyte antigen-A2 antibody and vaginally delivered a newborn who had no symptom. The third woman with a history of recurrent pregnancy losses carried anti-HPA-4b antibody, and delivered a newborn by a cesarean section who received platelet transfusions and immunoglobulin infusions. Antiplatelet antibody screening may be helpful in women who have a history of blood transfusion, or previous neonates with thrombocytopenia or intracranial hemorrhage.
• Japan Society of Gynecologic Oncology guidelines 2017 for the treatment of uterine cervical cancer.
  Yasuhiko Ebina; Mikio Mikami; Satoru Nagase; Tsutomu Tabata; Masanori Kaneuchi; Hironori Tashiro; Masaki Mandai; Takayuki Enomoto; Yoichi Kobayashi; Hidetaka Katabuchi; Nobuo Yaegashi; Yasuhiro Udagawa; Daisuke Aoki
  International journal of clinical oncology, 24, 1, 1, 19, Jan. 2019, [Peer-reviewed], [Lead author, Corresponding author], [Domestic magazines]
  English, Scientific journal, The Japan Society of Gynecologic Oncology (JSGO) Guidelines 2017 for the Treatment of Uterine Cervical Cancer are for the purpose of providing standard treatment strategies for cervical cancer, indicating treatment methods currently considered appropriate for cervical cancer, minimizing variances in treatment methods among institutions, improving the safety of treatment and prognosis of diseases, reducing the economic and psychosomatic burden of patients by promoting performance of appropriate treatment, and enhancing mutual understanding between patients and healthcare professionals. The guidelines were prepared through consensus of the JSGO Guideline Committee, based on careful review of evidence gathered through the literature searches and in view of the medical health insurance system and actual clinical practice situations in Japan. The guidelines comprise eight chapters and five algorithms. The main features of the 2017 revision are as follows: (1) evidence was collected using a search formula and with cooperation of the Japan Library Association. The bibliographical search formula was placed at the end of the book; (2) regarding clinical questions (CQs) where evidence or clinical inspection in Japan was lacking, opinions of the Guidelines Committee were described as "proposals for future directions"; (3) cervical intraepithelial neoplasia (CIN) 3 and adenocarcinoma in situ (AIS) were treated as a cervical precancerous lesion; (4) the CQs of endoscopic surgery, radical trachelectomy, and sentinel node biopsy were newly added in Chapter 3, "primary treatment for stage IB-II cervical cancer"; and (5) the CQ about hormone replacement therapy after cancer treatment was newly established. Each recommendation is accompanied by a classification of recommendation categories based on the consensus reached by the Guideline Committee members. Here, we present the English version of the JSGO Guidelines 2017 for the Treatment of Uterine Cervical Cancer.
• A retrospective analysis of giant ovarian tumors weighing more than 5,000 grams
  Yoshiya Miyahara; Hitomi Imafuku; Yuka Murata; Yasuhiko Ebina; Hideto Yamada
  European Journal of Gynaecological Oncology, 40, 4, 563, 566, S.O.G. CANADA Inc., 2019
  English, Scientific journal
• Clinical factor associated with congenital cytomegalovirus infection in pregnant women with non-primary infection.
  Hideto Yamada; Kenji Tanimura; Shinya Tairaku; Ichiro Morioka; Masashi Deguchi; Mayumi Morizane; Satoshi Nagamata; Kana Ozaki; Yasuhiko Ebina; Toshio Minematsu
  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 24, 9, 702, 706, Sep. 2018, [Peer-reviewed], [International Magazine]
  English, Scientific journal, The aim of this nested case-control study was to evaluate clinical factors associated with the occurrence of congenital cytomegalovirus (CMV) infection in pregnant women with non-primary CMV infection. In a cohort study of CMV screening for 2193 pregnant women and their newborns, seven newborns with congenital CMV infection were identified among 1287 pregnant women with non-primary CMV infection that was defined as negative IgM and positive IgG with IgG avidity index >45%. In the 1287 women with non-primary CMV infection, clinical findings and complications were compared between pregnancies with and without congenital CMV infection. Clinical factors associated with the occurrence of congenital CMV infection were evaluated. The birth weight of newborns with congenital CMV infection was less than that of newborns without congenital infection (p < 0.05). Univariate logistic regression analyses demonstrated that threatened premature delivery (OR 10.6, 95%CI 2.0-55.0; p < 0.01) and multiple pregnancy (OR 7.1, 95%CI 1.4-37.4; p < 0.05) were associated with congenital infection. Multivariable logistic regression analyses demonstrated that threatened premature delivery (OR 8.4, 95%CI 1.5-48.1; p < 0.05) was a single risk factor for congenital CMV infection in pregnant women with non-primary CMV infection. This study revealed for the first time that threatened premature delivery was associated with the occurrence of congenital CMV infection in pregnant women with non-primary CMV infection, the pathophysiology of which may be closely associated with CMV reactivation during pregnancy.
• Risk factors for deep venous thrombosis in women with ovarian cancer.
  Yasuhiko Ebina; Mihoko Uchiyama; Hitomi Imafuku; Kaho Suzuki; Yoshiya Miyahara; Hideto Yamada
  Medicine, 97, 23, e11009, Jun. 2018, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
  English, Scientific journal, We aim to clarify the incidence of deep venous thrombosis (DVT) before treatment in women with ovarian cancer and identify risk factors for DVT.In this prospective study, 110 women underwent venous ultrasonography before cancer treatment and D-dimer levels were measured. We investigated factors predicting DVT by logistic regression.DVT was detected in 25 of 110 women (22.7%) and pulmonary thromboembolism was coexisted in 2 women (1.8%). A total of 21 women (84.4%) with DVT were asymptomatic. D-dimer levels in women with DVT (median, 10.9; range, <0.5-98.2 μg/mL) were significantly higher than those in women without DVT (2.0; <0.5-60.8 μg/mL; P < .01). When 10.9 μg/mL was used as a cutoff value for D-dimer levels to predict DVT, specificity, sensitivity, and positive and negative predictive values were 92.9%, 52.0%, 68.4%, and 86.8%, respectively. The multivariate analysis demonstrated that D-dimer level (odds ratio [OR], 19.7; 95% confidence interval [CI], 5.89-76.76) and clear cell histology (OR, 7.1; 95% CI, 2.12-25.67) were independent factors predicting DVT.Asymptomatic DVT occurred with great frequency before treatment in patients with ovarian cancer. High D-dimer level and clear cell pathology is associated with a higher DVT risk.
• Ultrasound and MRI Findings of Twin Pregnancies with Complete Hydatidiform Mole and Coexisting Normal Fetus: Two Case Reports.
  Hitomi Imafuku; Yoshiya Miyahara; Yasuhiko Ebina; Hideto Yamada
  The Kobe journal of medical sciences, 64, 1, E1-E5, E5, 28 May 2018, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, BACKGROUND: Both twin pregnancies with complete hydatidiform mole and coexisting normal fetus (CHMCF) and partial hydatidiform mole can be found in association with a live fetus and a placenta displaying a molar degeneration. Two cases of CHMCF using magnetic resonance imaging (MRI) for a diagnosis are reported. CASE: In the first, CHMCF was suspected at 12 weeks of gestation. At 18 weeks of gestation, the existence of molar placenta and a sac separating from fetus and normal placenta was clearly depicted on MRI. At 19 weeks of gestations, she had termination of pregnancy because of a development of gestational trophoblastic neoplasia (GTN) and started chemotherapy. In the second case, CHMCF was suspected at 14 weeks of gestation. MRI demonstrated the existence of molar placenta and a sac separating from fetus and normal placenta. She chose induced abortion and there was no evidence of GTN during the 1 year-follow up period. Pathological examination in both cases was consistent with a complete hydration mole and a coexisting normal female fetus. CONCLUSION: MRI was useful for an accurate diagnosis for CHMCF.
• Comparison of dosimetric parameters in the treatment planning of magnetic resonance imaging-based intracavitary image-guided adaptive brachytherapy with and without optimization using the central shielding technique.
  Ryo Nishikawa; Kenji Yoshida; Yasuhiko Ebina; Mayumi Omoteda; Daisuke Miyawaki; Takeaki Ishihara; Yasuo Ejima; Hiroaki Akasaka; Hitoaki Satoh; Katsusuke Kyotani; Satoru Takahashi; Ryohei Sasaki
  Journal of radiation research, 59, 3, 316, 326, 01 May 2018, [Peer-reviewed], [International Magazine]
  English, Scientific journal, This study aimed to compare dosimetric parameters between non-optimized and optimized treatment planning (NOP and OP, respectively) of magnetic resonance imaging (MRI) -based intracavitary (IC) image-guided adaptive brachytherapy (IGABT) using the central shielding (CS) technique for cervical cancer. Fifty-three patients treated with external beam radiotherapy using CS and MRI-based IGABT with the IC approach alone were evaluated. The total high-risk clinical target volume (HR-CTV) D90 was aimed at >70 Gy equivalent dose in 2 Gy fractions (EQD2). In the small HR-CTV group (≤30 cm3), the mean D90s for NOP/OP were 98.6/80.7 Gy. In the large (30.1-40 cm3) and extensive (>40 cm3) HR-CTV groups, the mean D90s were 81.9/77.5 and 71.1/73.6 Gy, respectively. The mean D2cc values for organs at risks (OARs) in OP were acceptable in all groups, despite the high bladder D2cc in the NOP. The correlation between HR-CTV at first brachytherapy (BT) and NOP D90 was stronger than that between HR-CTV at first BT and OP D90. The targeted HR-CTV D90 and dose constraints of D2cc for OARs were both achieved in 16 NOP/47 OP patients for the bladder, 39/50 for the rectum, and 47/50 for the sigmoid colon (P < 0.001, P = 0.007, and P = 0.34, respectively). For small tumors, the role of optimization was to reduce the D2cc for OARs while maintaining the targeted D90. However, optimization was of limited value for extensive tumors. Methods of optimization in IGABT with CS for cervical cancer should be standardized while considering its effectiveness and limitations.
• 卵巣過剰刺激症候群の加療中に腹膜妊娠が判明し、腹腔鏡下手術で治療し得た一例
  鈴木 嘉穂; 蝦名 康彦; 長又 哲史; 白川 得朗; 今福 仁美; 若橋 宣; 宮原 義也
  日本産科婦人科内視鏡学会雑誌, 34, 1, 174, 178, (一社)日本産科婦人科内視鏡学会, Apr. 2018
  Japanese, 36歳(0経妊)。前医にて不妊治療中であったが、周期20日目に気分不良、腹痛、腹部膨満、ふらつきを自覚し、当院へ救急搬送された。臨床経過および経腟超音波断層検査、腹部単純CT所見よりOHSS(卵巣過剰刺激症候群)と診断され、保存的加療を行ったが症状は改善せず、腫大卵巣の縮小を認めなかった。周期40日目に血中hCGを測定したところ上昇がみられ、経腟超音波断層検査および腹部単純MRIにて異所性妊娠が疑われ、全身麻酔下で審査腹腔鏡下手術を行ったところ、腹膜妊娠が判明した。術後は血中hCGの低下を認め、術後7日目に退院となった。
• A novel scoring system for predicting adherent placenta in women with placenta previa.
  Kenji Tanimura; Mayumi Morizane; Masashi Deguchi; Yasuhiko Ebina; Utaru Tanaka; Yoshiko Ueno; Kazuhiro Kitajima; Tetsuo Maeda; Kazuro Sugimura; Hideto Yamada
  Placenta, 64, 27, 33, Apr. 2018, [Peer-reviewed], [International Magazine]
  English, Scientific journal, INTRODUCTION: Placenta previa (PP) is one of the most significant risk factors for adherent placenta (AP). The aim of this study was to evaluate the diagnostic efficacy of a novel scoring system for predicting AP in pregnant women with PP. METHODS: This prospective cohort study enrolled 175 women with PP. The placenta previa with adherent placenta score (PPAP score) is composed of 2 categories: (1) past history of cesarean section (CS), surgical abortion, and/or uterine surgery; and (2) ultrasonography and magnetic resonance imaging findings. Each category is graded as 0, 1, 2, or 4 points, yielding a total score between 0 and 24. When women with PP had PPAP score ≥8, they were considered to be at a high risk for AP and received placement of preoperative internal iliac artery occlusion balloon catheters. If they were found to have AP during CS, they underwent hysterectomy or placenta removal using advanced bipolar with balloon catheter occlusion. The predictive accuracy of PPAP score was evaluated. RESULTS: In total, 23 of the 175 women with PP were diagnosed as having AP, histopathologically or clinically. Twenty-one of 24 women with PPAP score ≥8 had AP, whereas two of 151 women with PPAP score <8 had AP. The scoring system yielded 91.3% sensitivity, 98.0% specificity, 87.5% positive predictive value, and 98.7% negative predictive value for predicting AP in women with PP. DISCUSSION: This prospective study demonstrated that PPAP scoring system may be useful for predicting AP in women with PP.
• Effectiveness of high-dose i.v. immunoglobulin therapy for pregnant women with aspirin-heparin-resistant secondary antiphospholipid syndrome.
  Yoko Maesawa; Masashi Deguchi; Kenji Tanimura; Mayumi Morizane; Yasuhiko Ebina; Hideto Yamada
  Reproductive medicine and biology, 17, 2, 149, 154, Apr. 2018, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, Purpose: This study aimed to assess the efficacy of high-dose i.v. immunoglobulin (HIVIg) therapy in pregnant women with antiphospholipid syndrome (APS) secondary to systemic lupus erythematosus with a history of pregnancy failure, despite receiving low-dose aspirin plus unfractionated heparin therapy, of which condition being designated as "aspirin-heparin-resistant APS" (AHRAPS). Methods: The HIVIg therapy (20 g/d, 5 days) was performed for the pregnancies of five women with AHRAPS. Results: Five of the eight pregnancies ended in live births. The gestational ages of delivery in four of the five pregnancies were extended, compared with previous pregnancies. The HIVIg therapy was considered to be successful for these four pregnancies. Excluding one pregnancy that ended in miscarriage with an abnormal chromosome karyotype of the villi, the HIVIg therapy was considered to be successful in four (57.1%) of the seven pregnancies of the women with AHRAPS. Although all the live newborns were prematurely delivered, no adverse effect of the HIVIg therapy was observed. Conclusions: The HIVIg therapy might be beneficial as an immune modifier for pregnant women with AHRAPS. However, the precise indication of which women with AHRAPS who should receive HIVIg therapy remains unknown.
• Decidual CD68+ HLA-DR+ CD163- M1 macrophages increase in miscarriages with normal fetal chromosome.
  Shigeki Shimada; Yasuhiko Ebina; Norifumi Iijima; Masashi Deguchi; Hideto Yamada
  American journal of reproductive immunology (New York, N.Y. : 1989), 79, 2, Feb. 2018, [Peer-reviewed], [International Magazine]
  English, Scientific journal, PROBLEM: Is an abnormal increase or decrease of M1/M2 macrophages observed in the deciduae of miscarriages with normal fetal chromosome (MN)? METHODS OF STUDY: Deciduae of 18 MN and 26 miscarriages with abnormal fetal chromosome (MA) were obtained. Additionally, deciduae from 15 women whose pregnancies ended in induced abortions (IA) and endometriums at the mid-luteal phase from 19 non-pregnant women endomeriums of mid-luteal phases (EM) were obtained. Macrophages were analyzed by flow cytometry using monoclonal antibodies for CD68, HLA-DR, and CD163. RESULTS: M1 macrophages, defined as CD68+ HLA-DR+ CD163- cells, increased in MN compared with MA or IA. M2 macrophages, defined as CD68+ HLA-DR- CD163+ cells, increased in the deciduae of MA and IA compared with EM. However, this increase was not observed in the deciduae of MN. CONCLUSION: Our findings of phenotypic characters of decidual macrophages in MN provide additional evidence that M2 polarization is favorable for the maintenance of early stages of pregnancy.
• Factors associated with adverse pregnancy outcomes in women with systematic lupus erythematosus.
  Masashi Deguchi; Yoko Maesawa; Shino Kubota; Mayumi Morizane; Kenji Tanimura; Yasuhiko Ebina; Hideto Yamada
  Journal of reproductive immunology, 125, 39, 44, Feb. 2018, [Peer-reviewed], [International Magazine]
  English, Scientific journal, The aim of this prospective study was to determine clinical factors associated with adverse pregnancy outcomes in women with systematic lupus erythematosus (SLE). Fifty-six pregnancies from 46 women with SLE were enrolled. Risk factors for pregnancy loss, premature delivery, hypertensive disorders of pregnancy (HDP), and light-for-date neonate (LFD), were evaluated. Univariate and multivariate logistic regression analyses revealed a history of two or more pregnancy losses before 10 gestational weeks (GW) (OR 11.5, 95%CI 1.72-76.8) as a risk factor for pregnancy loss; low levels of blood complements (OR 7.55, 95%CI 1.10-51.9) and antiphospholipid syndrome (OR 26.5, 95%CI 3.17-219) as risk factors for premature delivery before 37 GW; SLEDAI score at conception (OR 1.68, 95%CI 1.05-2.68) and positive tests for two or more antiphospholipid antibodies (OR 6.89, 95%CI 1.13-41.9) as risk factors for premature delivery before 34 GW; prednisolone therapy >14mg/day (OR 7.55, 95%CI 1.10-51.9) as a risk factor for HDP; and low dose aspirin therapy (OR 0.21, 95%CI 0.05-0.97) decreased the risk for LFD neonate. These results have important implications for clinicians managing SLE complicated pregnancy.
• Universal Screening With Use of Immunoglobulin G Avidity for Congenital Cytomegalovirus Infection.
  Kenji Tanimura; Shinya Tairaku; Ichiro Morioka; Kana Ozaki; Satoshi Nagamata; Mayumi Morizane; Masashi Deguchi; Yasuhiko Ebina; Toshio Minematsu; Hideto Yamada
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 65, 10, 1652, 1658, 30 Oct. 2017, [Peer-reviewed], [International Magazine]
  English, Scientific journal
• PCR tests for uterine cervical secretion are promising noninvasive methods for predicting congenital cytomegalovirus infection.
  Kenji Tanimura; Yasuhiko Ebina; Hideto Yamada
  Expert review of molecular diagnostics, 17, 6, 535, 537, Jun. 2017, [Peer-reviewed], [Invited], [International Magazine]
  English, Scientific journal
• Natural killer cell activity in women with recurrent miscarriage: Etiology and pregnancy outcome.
  Yasuhiko Ebina; Yukari Nishino; Masashi Deguchi; Yoko Maesawa; Yuki Nakashima; Hideto Yamada
  Journal of reproductive immunology, 120, 42, 47, Apr. 2017, [Peer-reviewed], [Lead author], [International Magazine]
  English, Scientific journal
• A pregnant woman with a surgical site infection after mesh repair of an abdominal wall incisional hernia: A case report
  Kana Ozaki; Kenji Tanimura; Yasuhiko Ebina; Kiyonori Kanemitsu; Hideto Yamada
  Journal of Medical Case Reports, 11, 1, 66, BioMed Central Ltd., 11 Mar. 2017, [Peer-reviewed]
  English, Scientific journal
• Lymphangioleiomyomatosis observed in the dissected lymph node and myometrium in a patient that underwent radical operation for endometrial cancer
  H. Morita; Y. Miyahara; Y. Ueno; K. Otani; F. Kawakami; Y. Ebina; H. Yamada
  EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 38, 5, 815, 817, 2017, [Peer-reviewed]
  English, Scientific journal
• Prediction of Congenital Cytomegalovirus Infection in High-Risk Pregnant Women
  Kenji Tanimura; Shinya Tairaku; Yasuhiko Ebina; Ichiro Morioka; Satoshi Nagamata; Kana Deguchi; Mayumi Morizane; Masashi Deguchi; Toshio Minematsu; Hideto Yamada
  CLINICAL INFECTIOUS DISEASES, 64, 2, 159, 165, Jan. 2017, [Peer-reviewed]
  English, Scientific journal
• 【産婦人科感染症の最前線】 母子に影響を与える感染症 トキソプラズマ感染症
  山田秀人; Deguchi Masashi; Morioka Ichiro; Tanimura Kenji; Ebina Yasuhiko
  産婦人科の実際, 65, 13号, 1719, 1724, 金原出版, Dec. 2016, [Invited]
  Japanese, Scientific journal
• Divergence of helper, cytotoxic, and regulatory T cells in the decidua from miscarriage
  Yasuhiko Ebina; Shigeki Shimada; Masashi Deguchi; Yoko Maesawa; Norifumi Iijima; Hideto Yamada
  AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 76, 3, 199, 204, Sep. 2016, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Japan Society of Gynecologic Oncology guidelines 2013 for the treatment of uterine body neoplasms
  Yasuhiko Ebina; Hidetaka Katabuchi; Mikio Mikami; Satoru Nagase; Nobuo Yaegashi; Yasuhiro Udagawa; Hidenori Kato; Kaneyuki Kubushiro; Kiyoshi Takamatsu; Kazuhiko Ino; Hiroyuki Yoshikawa
  INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 21, 3, 419, 434, Jun. 2016, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal
• A case of uterine leiomyosarcoma with long-term disease control by pazopanib
  Satoshi Nagamata; Yasuhiko Ebina; Yumika Yamano; Takeo Miyamoto; Mitsuhiro Nishijima; Hideto Yamada
  Kobe Journal of Medical Sciences, 62, 2, E45, E48, Kobe University School of Medicine, 2016, [Peer-reviewed]
  English, Scientific journal
• Protein S deficiency complicated pregnancy in women with recurrent pregnancy loss
  Nanae Shinozaki; Yasuhiko Ebina; Masashi Deguchi; Kenji Tanimura; Mayumi Morizane; Hideto Yamada
  GYNECOLOGICAL ENDOCRINOLOGY, 32, 8, 672, 674, 2016, [Peer-reviewed]
  English, Scientific journal
• The IgG avidity value for the prediction of Toxoplasma gondii infection in the amniotic fluid
  Kenji Tanimura; Akira Nishikawa; Shinya Tairaku; Nanae Shinozaki; Masashi Deguchi; Mayumi Morizane; Yasuhiko Ebina; Ichiro Morioka; Hideto Yamada
  JOURNAL OF INFECTION AND CHEMOTHERAPY, 21, 9, 668, 671, Sep. 2015, [Peer-reviewed]
  English, Scientific journal
• Low levels of plasma protein S, protein C and coagulation factor XII during early pregnancy and adverse pregnancy outcome
  Yasuhiko Ebina; Masahiro Ieko; Sumiyoshi Naito; Gen Kobashi; Masashi Deguchi; Hisanori Minakami; Tatsuya Atsumi; Hideto Yamada
  THROMBOSIS AND HAEMOSTASIS, 114, 1, 65, 69, Jul. 2015, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Preoperative risk stratification using metabolic parameters of F-18-FDG PET/CT in patients with endometrial cancer
  Kazuhiro Kitajima; Yuko Suenaga; Yoshiko Ueno; Tetsuo Maeda; Yasuhiko Ebina; Hideto Yamada; Takashi Okunaga; Kazuhiro Kubo; Keitarou Sofue; Tomonori Kanda; Yukihisa Tamaki; Kazuro Sugimura
  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 42, 8, 1268, 1275, Jul. 2015, [Peer-reviewed]
  English, Scientific journal
• Medium-dose intravenous immunoglobulin therapy for women with six or more recurrent miscarriages
  Hideto Yamada; Masashi Deguchi; Yoko Maesawa; Yuki Nakajima; Yukari Nishino; Kenji Tanimura; Yasuhiko Ebina
  JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 109, 48, 51, Jun. 2015, [Peer-reviewed]
  English, Scientific journal
• Rapid increase in the serum Cytomegalovirus IgG avidity index in women with a congenitally infected fetus
  Yasuhiko Ebina; Toshio Minematsu; Ichiro Morioka; Masashi Deguchi; Shinya Tairaku; Kenji Tanimura; Ayako Sonoyama; Satoshi Nagamata; Mayumi Morizane; Hideto Yamada
  JOURNAL OF CLINICAL VIROLOGY, 66, 44, 47, May 2015, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal
• Japan Society of Gynecologic Oncology guidelines 2011 for the treatment of uterine cervical cancer
  Yasuhiko Ebina; Nobuo Yaegashi; Hidetaka Katabuchi; Satoru Nagase; Yasuhiro Udagawa; Toru Hachisuga; Tsuyoshi Saito; Mikio Mikami; Yoichi Aoki; Hiroyuki Yoshikawa
  INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 20, 2, 240, 248, Apr. 2015, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal
• Prediction of adherent placenta in pregnancy with placenta previa using ultrasonography and magnetic resonance imaging
  Kenji Tanimura; Yui Yamasaki; Yasuhiko Ebina; Masashi Deguchi; Yoshiko Ueno; Kazuhiro Kitajima; Hideto Yamada
  EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 187, 41, 44, Apr. 2015, [Peer-reviewed]
  English, Scientific journal
• beta 2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome
  Kenji Tanimura; Hui Jin; Tadahiro Suenaga; Satoko Morikami; Noriko Arase; Kazuki Kishida; Kouyuki Hirayasu; Masako Kohyama; Yasuhiko Ebina; Shinsuke Yasuda; Tetsuya Horita; Kiyoshi Takasugi; Koichiro Ohmura; Ken Yamamoto; Ichiro Katayama; Takehiko Sasazuki; Lewis L. Lanier; Tatsuya Atsumi; Hideto Yamada; Hisashi Arase
  BLOOD, 125, 18, 2835, 2844, Apr. 2015, [Peer-reviewed]
  English, Scientific journal
• History of biochemical pregnancy was associated with the subsequent reproductive failure among women with recurrent spontaneous abortion
  Yoko Maesawa; Hideto Yamada; Masashi Deguchi; Yasuhiko Ebina
  GYNECOLOGICAL ENDOCRINOLOGY, 31, 4, 306, 308, Apr. 2015, [Peer-reviewed]
  English, Scientific journal
• Human recombinant H2 relaxin induces AKT and GSK3β phosphorylation and HTR-8/SVneo cell proliferation.
  Yoni Astuti; Koji Nakabayashi; Masashi Deguchi; Yasuhiko Ebina; Hideto Yamada
  The Kobe journal of medical sciences, 61, 1, E1-8, 8, 1, 24 Mar. 2015, [Peer-reviewed], [Domestic magazines]
  English, Relaxin is essential for trophoblast development during pregnancy. Evidence shows that relaxin increases trophoblast cell migration capacity. Here, we show the effect of relaxin on protein kinase B (AKT) activation and glycogen synthase kinase 3-beta (GSK3β) inactivation as well as on the proliferation of HTR-8/SVneo cells, a model of human extravillous trophoblast (EVT). HTR-8/SVneo cells were treated with different doses of human recombinant (rH2) relaxin in serum-deprived conditions and treated for increasing time with 1 ng/mL of rH2 relaxin. Western blot analysis was performed to detect pAKT, AKT, pGSK3β, GSK3β, and actin expression. Proliferation of HTR-8/SVneo cells was analyzed by MTS assay. rH2 relaxin treatment increased the ratio of pAKT/AKT, pGSK3β/GSK3β, and proliferation in HTR-8/SVneo cells. Furthermore, AKT and GSK3β activation by rH2 relaxin was inhibited by a phosphoinositide 3-kinase (PI3K) inhibitor. This study suggests that rH2 relaxin induces AKT and GSK3β phosphorylation as well as proliferation in HTR-8/SVneo cells.
• Low total IgM values and high cytomegalovirus loads in the blood of newborns with symptomatic congenital cytomegalovirus infection
  Yoko Kobayashi; Ichiro Morioka; Tsubasa Koda; Yuji Nakamachi; Yoko Okazaki; Yoriko Noguchi; Miki Ogi; Masatsugu Chikahira; Kenji Tanimura; Yasuhiko Ebina; Toru Funakoshi; Masanobu Ohashi; Kazumoto Iijima; Naoki Inoue; Seiji Kawano; Hideto Yamada
  JOURNAL OF PERINATAL MEDICINE, 43, 2, 239, 243, Mar. 2015, [Peer-reviewed]
  English, Scientific journal
• Nationwide survey of mother-to-child infections in Japan
  Hideto Yamada; Shinya Tairaku; Ichiro Morioka; Ayako Sonoyama; Kenji Tanimura; Masashi Deguchi; Satoshi Nagamata; Yasuhiko Ebina
  JOURNAL OF INFECTION AND CHEMOTHERAPY, 21, 3-4, 161, 164, Mar. 2015, [Peer-reviewed]
  English, Scientific journal
• パルボウイルスB19母子感染－全国参加施設を対象とした実態調査
  蝦名康彦
  小児科, 56, 2, 191, 198, 金原出版, Feb. 2015, [Peer-reviewed], [Invited], [Lead author, Corresponding author]
  Japanese
• Viper bite during pregnancy: case report
  M. Nishimoto; Y. Miyahara; Y. Ebina; M. Deguchi; S. Matsuoka; H. Yamada
  CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, 42, 2, 243, 245, 2015, [Peer-reviewed]
  English, Scientific journal
• Role of Diffusion Weighted Imaging and Contrast-Enhanced MRI in the Evaluation of Intrapelvic Recurrence of Gynecological Malignant Tumor
  Kazuhiro Kitajima; Utaru Tanaka; Yoshiko Ueno; Tetsuo Maeda; Yuko Suenaga; Satoru Takahashi; Masashi Deguchi; Yoshiya Miyahara; Yasuhiko Ebina; Hideto Yamada; Masakatsu Tsurusaki; Yukihisa Tamaki; Kazuro Sugimura
  PLOS ONE, 10, 1, e0117411, Jan. 2015, [Peer-reviewed]
  English, Scientific journal
• Pathogenesis of combined high-grade squamous intraepithelial lesion and adenocarcinoma in situ of the uterine cervix: human papillomavirus genotype and methylation status and immunohistochemical study.
  Fumi Kawakami; Shuho Semba; Hiroe Itami; Noriko Oka; Tamotsu Sudo; Yasuhiko Ebina; Chiho Ohbayashi; Yoshiki Mikami; Hiroshi Yokozaki; Tomoo Itoh
  The Kobe journal of medical sciences, 60, 3, E66-73, 73, 06 Nov. 2014, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, To determine the etiology of combined high-grade squamous intraepithelial lesion (HSIL) and adenocarcinoma in situ (AIS) of the uterine cervix, we examined human papillomavirus (HPV) subtypes, methylation status of the HPV-16 L1 gene, and immunohistochemical staining pattern of Krt7 in 8 cases of combined HSIL and AIS. Overall, 6 (75%) of 8 patients with combined HSIL and AIS were infected by the same subtype of HPV in both HSIL and AIS (cases 1-5, HPV-16; and case 6, HPV-18), whereas 2 (25%) patients showed infection with different subtypes of HPV (case 7, HPV-31 and -18; and case 8, HPV-52 and -16, in HSIL and AIS, respectively). The degrees of methylation at CpG islands within the HPV-16 L1 gene were almost equivalent between HSIL and AIS in cases 1-4, whereas a great difference in CpG methylation patterns between two was seen in only 1 case (case 5). In addition, both patients infected with different subtypes of HPV between HSIL and AIS were positive for Krt7 only within the AIS component. Based on these results, we propose two distinct developmental pathways of combined HSIL and AIS of the uterine cervix, the common pathway and the individual pathway.
• Pathogenesis of combined high-grade squamous intraepithelial lesion and adenocarcinoma in situ of the uterine cervix: human papillomavirus genotype and methylation status and immunohistochemical study.
  Fumi Kawakami; Shuho Semba; Hiroe Itami; Noriko Oka; Tamotsu Sudo; Yasuhiko Ebina; Chiho Ohbayashi; Yoshiki Mikami; Hiroshi Yokozaki; Tomoo Itoh
  The Kobe journal of medical sciences, 60, 3, E66-73, 73, 3, 06 Nov. 2014, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, To determine the etiology of combined high-grade squamous intraepithelial lesion (HSIL) and adenocarcinoma in situ (AIS) of the uterine cervix, we examined human papillomavirus (HPV) subtypes, methylation status of the HPV-16 L1 gene, and immunohistochemical staining pattern of Krt7 in 8 cases of combined HSIL and AIS. Overall, 6 (75%) of 8 patients with combined HSIL and AIS were infected by the same subtype of HPV in both HSIL and AIS (cases 1-5, HPV-16; and case 6, HPV-18), whereas 2 (25%) patients showed infection with different subtypes of HPV (case 7, HPV-31 and -18; and case 8, HPV-52 and -16, in HSIL and AIS, respectively). The degrees of methylation at CpG islands within the HPV-16 L1 gene were almost equivalent between HSIL and AIS in cases 1-4, whereas a great difference in CpG methylation patterns between two was seen in only 1 case (case 5). In addition, both patients infected with different subtypes of HPV between HSIL and AIS were positive for Krt7 only within the AIS component. Based on these results, we propose two distinct developmental pathways of combined HSIL and AIS of the uterine cervix, the common pathway and the individual pathway.
• The IgG avidity value for the prediction of congenital cytomegalovirus infection in a prospective cohort study
  Yasuhiko Ebina; Toshio Minematsu; Ayako Sonoyama; Ichiro Morioka; Naoki Inoue; Shinya Tairaku; Satoshi Nagamata; Kenji Tanimura; Mayumi Morizane; Masashi Deguchi; Hideto Yamada
  JOURNAL OF PERINATAL MEDICINE, 42, 6, 755, 759, Nov. 2014, [Peer-reviewed], [Lead author]
  English, Scientific journal
• 卵巣奇形腫における悪性転化の術前予測についての検討
  牧原 夏子; 蝦名 康彦; 山崎 友維; 生橋 義之; 松岡 正造; 前田 哲雄; 川上 史; 山田 秀人
  日本産科婦人科内視鏡学会雑誌, 30, 1, 112, 116, (一社)日本産科婦人科内視鏡学会, Nov. 2014, [Peer-reviewed]
  Japanese, 病理診断にて卵巣成熟嚢胞性奇形腫(MCT)と診断した73例(良好群)と卵巣奇形腫の悪性転化と診断した4例(悪性群)の術前所見を後方視的に比較し、悪性転化のリスク診断に有用な因子を検討した。手術時年齢、最大腫瘍径、血清SCC抗原値、血清CEA値、骨盤MRIにおける腫瘍結節部分の造影効果の有無について解析した結果、卵巣奇形腫の悪性転化の術前診断に有用な因子として、60歳以上、腫瘍径10cm以上、血清SCC抗原2.5ng/ml以上、血清CEA 5.0ng/ml以上、骨盤MRIにて造影効果を示す充実部分を有するといった因子が選択された。術前の検査情報から得られる悪性転化のリスク、具体的な手術手技によるメリットとデメリットを十分に説明し、理解と納得を得た上で術式を選択してもらうことが重要であると考えられた。
• Prophylactic intravenous immunoglobulin injections to mothers with primary cytomegalovirus infection.
  Kenji Tanimura; Shinya Tairaku; Masashi Deguchi; Ayako Sonoyama; Mayumi Morizane; Yasuhiko Ebina; Ichiro Morioka; Hideto Yamada
  The Kobe journal of medical sciences, 60, 2, E25-9, 9, 2, 11 Jul. 2014, [Peer-reviewed], [Domestic magazines]
  English, The aim of this trial study was to assess the preventive efficacy of immunoglobulin with a high titer of anti-CMV antibody for mother-to-fetus cytomegalovirus (CMV) transmission among pregnant women with primary/acute CMV infection. The primary CMV infection in mothers was diagnosed by a positive test for CMV IgM and/or low IgG avidity. Intact type immunoglobulin with a high titer of anti-CMV antibody was injected intravenously at a dosage of 2.5-5.0 g/day for consecutive 3 days to mothers with primary CMV infection. Four pregnant women were enrolled. One pregnancy ended in no congenital infection, while two pregnancies ended in congenital CMV infection. The other one pregnancy was terminated. The mother-to-fetus CMV transmission rate was found to be high as 66.7% (2/3). This preliminary result suggests that intravenous immunoglobulin injections are not effective for the prevention of mother-to-fetus CMV transmission in the present protocol.
• Fusion of PET and MRI for staging of uterine cervical cancer: comparison with contrast-enhanced F-18-FDG PET/CT and pelvic MRI
  Kazuhiro Kitajima; Yuko Suenaga; Yoshiko Ueno; Tomonori Kanda; Tetsuo Maeda; Masashi Deguchi; Yasuhiko Ebina; Hideto Yamada; Satoru Takahashi; Kazuro Sugimura
  CLINICAL IMAGING, 38, 4, 464, 469, Jul. 2014, [Peer-reviewed]
  English, Scientific journal
• In vitro fertilization-embryo transfer pregnancy was a risk factor for hemorrhagic shock in women with placental polyp
  Yoshiya Miyahara; Natsuko Makihara; Yui Yamasaki; Yasuhiko Ebina; Masashi Deguchi; Hideto Yamada
  GYNECOLOGICAL ENDOCRINOLOGY, 30, 7, 502, 504, Jul. 2014, [Peer-reviewed]
  English, Scientific journal
• Present and future role of FDG-PET/CT imaging in the management of gynecologic malignancies
  Kazuhiro Kitajima; Yasuhiko Ebina; Kazuro Sugimura
  JAPANESE JOURNAL OF RADIOLOGY, 32, 6, 313, 323, Jun. 2014, [Peer-reviewed]
  English
• Risk factors for neonatal thyroid dysfunction in pregnancies complicated by Graves' disease
  Mizuki Uenaka; Kenji Tanimura; Shinya Tairaku; Ichiro Morioka; Yasuhiko Ebina; Hideto Yamada
  EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 177, 89, 93, Jun. 2014, [Peer-reviewed]
  English, Scientific journal
• The factors associated with the failure of transcatheter pelvic arterial embolization for intractable postpartum hemorrhage
  Yui Yamasaki; Hiroki Morita; Yoshiya Miyahara; Yasuhiko Ebina; Takuya Okada; Masato Yamaguchi; Hideto Yamada
  JOURNAL OF PERINATAL MEDICINE, 42, 3, 359, 362, May 2014, [Peer-reviewed]
  English, Scientific journal
• Nationwide survey of maternal screening for mother- to- child infections in Japan
  Hideto Yamada; Shinya Tairaku; Ichiro Morioka; Yasuhiko Ebina; Ayako Sonoyama; Kenji Tanimura; Masashi Deguchi; Satoshi Nagamata
  CONGENITAL ANOMALIES, 54, 2, 100, 103, May 2014, [Peer-reviewed]
  English, Scientific journal
• Management of Thromboembolism in Pregnant Women with Inherited Antithrombin
  YASUHIKO EBINA
  EXPERIMENTAL & CLINICAL CARDIOLOGY, 20, 6, 145, 159, Apr. 2014, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal
• Impact of FDG PET in optimizing patient selection for cytoreductive surgery in recurrent ovarian cancer
  Yasuhiko Ebina; Hidemichi Watari; Masanori Kaneuchi; Mahito Takeda; Masayoshi Hosaka; Masataka Kudo; Hideto Yamada; Noriaki Sakuragi
  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 41, 3, 446, 451, Mar. 2014, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal
• Awareness of and knowledge about mother-to-child infections in Japanese pregnant women
  Ichiro Morioka; Ayako Sonoyama; Shinya Tairaku; Yasuhiko Ebina; Satoshi Nagamata; Mayumi Morizane; Kenji Tanimura; Kazumoto Iijima; Hideto Yamada
  CONGENITAL ANOMALIES, 54, 1, 35, 40, Feb. 2014, [Peer-reviewed]
  English, Scientific journal
• Leiomyosarcoma of the broad ligament: a case report with CT and MRI images
  N. Makihara; T. Maeda; Y. Ebina; K. Kitajima; F. Kawakami; S. Hara; H. Yamada
  EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 35, 2, 174, 177, 2014, [Peer-reviewed]
  English, Scientific journal
• Value of fusion of PET and MRI in the detection of intra-pelvic recurrence of gynecological tumor: comparison with F-18-FDG contrast-enhanced PET/CT and pelvic MRI
  Kazuhiro Kitajima; Yuko Suenaga; Yoshiko Ueno; Tomonori Kanda; Tetsuo Maeda; Natsuko Makihara; Yasuhiko Ebina; Hideto Yamada; Satoru Takahashi; Kazuro Sugimura
  ANNALS OF NUCLEAR MEDICINE, 28, 1, 25, 32, Jan. 2014, [Peer-reviewed]
  English, Scientific journal
• Relaxin has anti-apoptotic effects on human trophoblast-derived HTR-8/SV neo cells
  Romana S. Z. Lodhi; Koji Nakabayashi; Kaho Suzuki; Ai Y. Yamada; Rhoichi Hazama; Yasuhiko Ebina; Hideto Yamada
  GYNECOLOGICAL ENDOCRINOLOGY, 29, 12, 1051, 1054, Dec. 2013, [Peer-reviewed]
  English, Scientific journal
• Value of fusion of PET and MRI for staging of endometrial cancer: Comparison with F-18-FDG contrast-enhanced PET/CT and dynamic contrast-enhanced pelvic MRI
  Kazuhiro Kitajima; Yuko Suenaga; Yoshiko Ueno; Tomonori Kanda; Tetsuo Maeda; Satoru Takahashi; Yasuhiko Ebina; Yoshiya Miyahara; Hideto Yamada; Kazuro Sugimura
  EUROPEAN JOURNAL OF RADIOLOGY, 82, 10, 1672, 1676, Oct. 2013, [Peer-reviewed]
  English, Scientific journal
• Low IgG avidity and ultrasound fetal abnormality predict congenital cytomegalovirus infection
  Ayako Sonoyama; Yasuhiko Ebina; Ichiro Morioka; Kenji Tanimura; Mayumi Morizane; Shinya Tairaku; Toshio Minematsu; Naoki Inoue; Hideto Yamada
  JOURNAL OF MEDICAL VIROLOGY, 84, 12, 1928, 1933, Dec. 2012, [Peer-reviewed]
  English, Scientific journal
• Low-dose non-enhanced CT versus full-dose contrast-enhanced CT in integrated PET/CT scans for diagnosing ovarian cancer recurrence
  Kazuhiro Kitajima; Yoshiko Ueno; Kayo Suzuki; Masato Kita; Yasuhiko Ebina; Hideto Yamada; Michio Senda; Tetsuo Maeda; Kazuro Sugimura
  EUROPEAN JOURNAL OF RADIOLOGY, 81, 11, 3557, 3562, Nov. 2012, [Peer-reviewed]
  English, Scientific journal
• A trial of immunoglobulin fetal therapy for symptomatic congenital cytomegalovirus infection
  Hideto Yamada; Mayumi Morizane; Kenji Tanimura; Ichiro Morioka; Yasuhiko Ebina; Hideo Matsuda; Masashi Yoshida; Hajime Wakamatsu; Kenichi Furuya; Jun Murotsuki; Shigeru Saito; Ichiro Kawabata; Yuichiro Takahashi; Toshiko Ueda; Yukiyasu Sato; Masato Kamitomo; Yuko Maruyama; Hideto Hirano; Takashi Yamada; Hisanori Minakami; Nobuo Yaegashi; Toshio Minematsu; Ryu Matsuoka; Michio Banzai; Tsuyomu Ikenoue
  JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 95, 1-2, 73, 79, Sep. 2012, [Peer-reviewed]
  English, Scientific journal
• Argatroban therapy for heparin-induced thrombocytopenia during pregnancy in a woman with hereditary antithrombin deficiency
  Kenji Tanimura; Yashuhiko Ebina; Ayako Sonoyama; Hiroki Morita; Shigeki Miyata; Hideto Yamada
  JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 38, 4, 749, 752, Apr. 2012, [Peer-reviewed]
  English, Scientific journal
• Recombinant H2 relaxin inhibits apoptosis and induces cell proliferation in cultured leiomyoma cells without affecting those in cultured normal myometrial cells
  Kaho Suzuki; Koji Nakabayashi; Ai Y. Yamada; Romana S. Z. Lodhi; Rhoichi Hazama; Yasuhiko Ebina; Hideto Yamada
  FERTILITY AND STERILITY, 97, 3, 734, 741, Mar. 2012, [Peer-reviewed]
  English, Scientific journal
• A high dose intravenous immunoglobulin therapy for women with four or more recurrent spontaneous abortions.
  Yamada H; Takeda M; Maezawa Y; Ebina Y; Hazama R; Tanimura K; Wakui Y; Shimada S
  ISRN obstetrics and gynecology, 2012, 512732, 2012, [Peer-reviewed]
• Less invasive new vaginoplasty using laparoscopy, atelocollagen sponge, and hand-made mould
  Yoshiya Miyahara; Shigeki Yoshida; Tokuro Shirakawa; Natsuko Makihara; Kiyoshi Niiya; Yasuhiko Ebina; Hideto Yamada
  Kobe Journal of Medical Sciences, 58, 5, E138, E144, 5, 2012, [Peer-reviewed]
  English, Scientific journal
• Resection of giant liver hemangioma in a pregnant woman with coagulopathy: Case report and literature review.
  Ebina Y; Hazama R; Nishimoto M; Tanimura K; Miyahara Y; Morizane M; Nakabayashi K; Fukumoto T; Ku Y; Yamada H
  Journal of prenatal medicine, 5, 93, 96, 4, Oct. 2011, [Peer-reviewed], [Lead author, Corresponding author]
• A nerve-sparing radical hysterectomy in invasive cervical cancer for preserving postsurgical bladder function
  MIYAHARA Yoshiya; YOSHIDA Shigeki; TAKEI Tomonobu; MAKIHARA Natsuko; HAZAMA Ryoichi; EBINA Yasuhiko; YAMADA Hideto
  ADVANCES IN OBSTETRICS AND GYNECOLOGY, 63, 3, 336, 338, THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2011, [Peer-reviewed]
  Japanese
• Epigenetic abnormality of SRY gene in the adult XY female with pericentric inversion of the Y chromosome
  Tomoko Mitsuhashi; Katsuhiko Warita; Teruo Sugawara; Yoshiaki Tabuchi; Ichiro Takasaki; Takashi Kondo; Fumio Hayashi; Zhi-Yu Wang; Yoshiki Matsumoto; Takanori Miki; Yoshiki Takeuchi; Yasuhiko Ebina; Hideto Yamada; Noriaki Sakuragi; Toshifumi Yokoyama; Takashi Nanmori; Hiroshi Kitagawa; Jeffrey A. Kant; Nobuhiko Hoshi
  CONGENITAL ANOMALIES, 50, 2, 85, 94, Jun. 2010, [Peer-reviewed]
  English, Scientific journal
• Global gene profiling and comprehensive bioinformatics analysis of a 46,XY female with pericentric inversion of the Y chromosome
  Tomoko Mitsuhashi; Katsuhiko Warita; Yoshiaki Tabuchi; Ichiro Takasaki; Takashi Kondo; Teruo Sugawara; Fumio Hayashi; Zhi-Yu Wang; Yoshiki Matsumoto; Takanori Miki; Yoshiki Takeuchi; Yasuhiko Ebina; Hideto Yamada; Noriaki Sakuragi; Toshifumi Yokoyama; Takashi Nanmori; Hiroshi Kitagawa; Jeffrey A. Kant; Nobuhiko Hoshi
  CONGENITAL ANOMALIES, 50, 1, 40, 51, Mar. 2010, [Peer-reviewed]
  English, Scientific journal
• High Dose Three-Dimensional Conformal Boost Using the Real-Time Tumor Tracking Radiotherapy System in Cervical Cancer Patients Unable to Receive Intracavitary Brachytherapy
  Hee Chul Park; Shinichi Shimizu; Akio Yonesaka; Kazuhiko Tsuchiya; Yasuhiko Ebina; Hiroshi Taguchi; Norio Katoh; Rumiko Kinoshita; Masayori Ishikawa; Noriaki Sakuragi; Hiroki Shirato
  YONSEI MEDICAL JOURNAL, 51, 1, 93, 99, Jan. 2010, [Peer-reviewed]
  English, Scientific journal
• Survival and Failure Pattern of Patients With Endometrial Cancer After Extensive Surgery Including Systematic Pelvic and Para-Aortic Lymphadenectomy Followed by Adjuvant Chemotherapy
  Hidemichi Watari; Takashi Mitamura; Masashi Moriwaki; Masayoshi Hosaka; Yoko Ohba; Satoko Sudo; Yukiharu Todo; Mahito Takeda; Yasuhiko Ebina; Noriaki Sakuragi
  INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 19, 9, 1585, 1590, Dec. 2009, [Peer-reviewed]
  English, Scientific journal
• Treatment of cervical cancer with adjuvant chemotherapy versus adjuvant radiotherapy after radical hysterectomy and systematic lymphadenectomy
  Masayoshi Hosaka; Hidemichi Watari; Mahito Takeda; Masashi Moriwaki; Yoko Hara; Yukiharu Todo; Yasuhiko Ebina; Noriaki Sakuragi
  JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 34, 4, 552, 556, Aug. 2008, [Peer-reviewed]
  English, Scientific journal
• Complete hydatidiform mole with coexisting dichorionic diamniotic twins following testicular sperm extraction and intracytoplasmic sperm injection
  Takahiro Yamada; Takao Matsuda; Masataka Kudo; Takashi Yamada; Masashi Moriwaki; Shinya Nishi; Yasuhiko Ebina; Hideto Yamada; Hidenori Kato; Tomoo Ito; Norio Wake; Noriaki Sakuragi; Hisanori Minakami
  JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 34, 1, 121, 124, Feb. 2008, [Peer-reviewed]
  English, Scientific journal
• Weekly paclitaxel/5-fluorouracil followed by platinum retreatment for patients with recurrent ovarian cancer: a single institution experience
  H. Watari; M. Hosaka; T. Mitamura; M. Moriwaki; Y. Ohba; Y. Todo; M. Takeda; Y. Ebina; N. Sakuragi
  EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 29, 6, 573, 577, 2008, [Peer-reviewed]
  English, Scientific journal
• A validation study of a scoring system to estimate the risk of lymph node metastasis for patients with endometrial cancer for tailoring the indication of lymphadenectomy
  Yukiharu Todo; Kazuhira Okamoto; Masaru Hayashi; Shinichiro Minobe; Eiji Nomura; Hitoshi Hareyama; Mahito Takeda; Yasuhiko Ebina; Hidemichi Watari; Noriaki Sakuragi
  GYNECOLOGIC ONCOLOGY, 104, 3, 623, 628, Mar. 2007, [Peer-reviewed]
  English, Scientific journal
• Urodynamic study on postsurgical bladder function in cervical cancer treated with systematic nerve-sparing radical hysterectomy
  Y Todo; M Kuwabara; H Watari; Y Ebina; M Takeda; M Kudo; R Yamamoto; N Sakuragi
  INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 16, 1, 369, 375, Jan. 2006, [Peer-reviewed]
  English, Scientific journal
• A study of oligosaccharide variants of alpha-fetoproteins produced by normal fetuses and fetuses with trisomy 21
  R Yamamoto; T Ohkouchi; K Tabata; Y Ebina; H Watari; M Kudo; K Shimizu; S Satomura; H Minakami; N Sakuragi
  ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 84, 12, 1145, 1149, Dec. 2005, [Peer-reviewed]
  English, Scientific journal
• Functional analysis of p53 gene and the prognostic impact of dominant-negative p53 mutation in endometrial cancer
  N Sakuragi; H Watari; Y Ebina; R Yamamoto; E Steiner; H Koelbl; M Yano; M Tada; T Moriuchi
  INTERNATIONAL JOURNAL OF CANCER, 116, 4, 514, 519, Sep. 2005, [Peer-reviewed]
  English, Scientific journal
• Lymph-vascular space invasion and number of positive para-aortic node groups predict survival in node-positive patients with endometrial cancer
  H Watari; Y Todo; M Takeda; Y Ebina; R Yamamoto; N Sakuragi
  GYNECOLOGIC ONCOLOGY, 96, 3, 651, 657, Mar. 2005, [Peer-reviewed]
  English, Scientific journal
• Lymphatic mapping and sentinel node identification as related to the primary sites of lymph node metastasis in early stage ovarian cancer
  H Negishi; M Takeda; T Fujimoto; Y Todo; Y Ebina; H Watari; R Yamamoto; H Minakami; N Sakuragi
  GYNECOLOGIC ONCOLOGY, 94, 1, 161, 166, Jul. 2004, [Peer-reviewed]
  English, Scientific journal
• Prenatal trisomy 21 screening using the Lens culinaris agglutinin-reactive alpha-fetoprotein ratio.
  Yamamoto R; Minobe S; Ebina Y; Watari H; Kudo M; Henmi F; Satomura S; Fujimoto S; Minakami H; Sakuragi N
  Congenital anomalies, 44, 2, 87, 92, 2, Jun. 2004, [Peer-reviewed]
  English
• Expression and methylation status of 14-3-3 sigma gene can characterize the different histological features of ovarian cancer
  M Kaneuchi; M Sasaki; Y Tanaka; H Shiina; M Verma; Y Ebina; E Nomura; R Yamamoto; N Sakuragi; R Dahiya
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 316, 4, 1156, 1162, Apr. 2004, [Peer-reviewed]
  English, Scientific journal
• F-18-fluoro-deoxyglucose positron emission tomography for the detection of recurrent ovarian cancer
  Y Ebina; D Akashi; M Takeda; H Watari; R Yamamoto; H Minakami; N Sakuragi
  PET AND MOLECULAR IMAGING: STATE OF THE ART AND FUTURE PERSPECTIVES, 1264, 222, 226, 2004, [Peer-reviewed]
  English, International conference proceedings
• Anticardiolipin beta 2-glycoprotein I antibody: Is a high titer related to unfavorable pregnancy outcome?
  H Yamada; EH Kato; M Morikawa; S Shimada; Y Ebina; N Sakuragi; S Suzuki; H Minakami
  SEMINARS IN THROMBOSIS AND HEMOSTASIS, 29, 6, 639, 643, Dec. 2003, [Peer-reviewed]
  English, Scientific journal
• Cytological features of cervical smears in serous adenocarcinoma of the endometrium
  Y Todo; S Minobe; K Okamoto; M Takeda; Y Ebina; H Watari; M Terashima; M Kaneuchi; R Yamamoto; N Sakuragi
  JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 33, 12, 636, 641, Dec. 2003, [Peer-reviewed]
  English, Scientific journal
• Combined use of magnetic resonance imaging, CA 125 assay, histologic type, and histologic grade in the prediction of lymph node metastasis in endometrial carcinoma
  Y Todo; N Sakuragi; R Nishida; T Yamada; Y Ebina; R Yamamoto; S Fujimoto
  AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 188, 5, 1265, 1272, May 2003, [Peer-reviewed]
  English, Scientific journal
• Increased levels of interleukin-6 in cervical secretions and assessment of the uterine cervix by transvaginal ultrasonography predict preterm premature rupture of the membranes
  T Kishida; H Yamada; Furuta, I; N Kobayashi; EK Hirayama; Y Ebina; N Sakuragi; S Fujimoto
  FETAL DIAGNOSIS AND THERAPY, 18, 2, 98, 104, Mar. 2003, [Peer-reviewed]
  English, Scientific journal
• Thromboprophylaxis with thrombophilia-complicated low molecular weight heparin in pregnancy
  Y Ebina; H Yamada; EH Kato; R Yamamoto; N Sakuragi; S Fujimoto
  JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 28, 5, 251, 257, Oct. 2002, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Para-aortic lymph node metastasis in relation to serum CA 125 levels and nuclear grade in endometrial carcinoma
  Y Ebina; N Sakuragi; H Hareyama; Y Todd; E Nomura; M Takeda; K Okamoto; H Yamada; R Yamamoto; S Fujimoto
  ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 81, 5, 458, 465, May 2002, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Detection of human papillomavirus DNA by PCR/microfluorometry for screening of cervical cancer
  A Yamaguchi; N Hashimoto; W Tsutae; K Seino; Y Ebina; T Tokino; N Sato; K Kikuchi
  CLINICA CHIMICA ACTA, 318, 1-2, 41, 49, Apr. 2002, [Peer-reviewed]
  English, Scientific journal
• Increased apoptosis of human fetal membranes in rupture of the membranes and chorioamnionitis
  S Kataoka; Furuta, I; H Yamada; EH Kato; Y Ebina; T Kishida; N Kobayashi; S Fujimoto
  PLACENTA, 23, 2-3, 224, 231, Feb. 2002, [Peer-reviewed]
  English, Scientific journal
• The presence of high-risk HPV DNA in cervical dysplastic cells is associated with clinical course: Long-term follow-up
  Y Ebina; Y Shirakawa; J Hino; T Sasaki; K Seino; K Kikuchi
  9TH BIENNIAL MEETING OF THE INTERNATIONL GYNECOLOGIC CANCER SOCIETY, 25, 27, 2002, [Peer-reviewed]
  English, International conference proceedings
• Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy
  G Kobashi; H Yamada; K Ohta; EH Kato; Y Ebina; S Fujimoto
  AMERICAN JOURNAL OF MEDICAL GENETICS, 103, 3, 241, 244, Oct. 2001, [Peer-reviewed]
  English, Scientific journal
• Persistent detection of alfa-fetoprotein in the vagina without overt preterm premature rupture of the membranes - Clinical and chemical characterizations
  T Kishida; H Yamada; Furuta, I; N Kobayashi; EK Hirayama; Y Ebina; K Cho; K Okuyama; S Fujimoto
  FETAL DIAGNOSIS AND THERAPY, 16, 5, 259, 264, Sep. 2001, [Peer-reviewed]
  English, Scientific journal
• High NK cell activity in early pregnancy correlates with subsequent abortion with normal chromosomes in women with recurrent abortion.
  Yamada H; Kato EH; Kobashi G; Ebina Y; Shimada S; Morikawa M; Sakuragi N; Fujimoto S
  American journal of reproductive immunology (New York, N.Y. : 1989), 46, 132, 136, 2, Aug. 2001, [Peer-reviewed]
• High NK cell activity in early pregnancy correlates with subsequent abortion with normal chromosomes in women with recurrent abortion
  H Yamada; EH Kato; G Kobashi; Y Ebina; S Shimada; M Morikawa; N Sakuragi; S Fujimoto
  AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 46, 2, 132, 136, Aug. 2001, [Peer-reviewed]
  English, Scientific journal
• Massive intravenous immunoglobulin treatment in pregnancy complicated by Guillain-Barre syndrome
  H Yamada; N Noro; EH Kato; Y Ebina; K Cho; S Fujimoto
  EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 97, 1, 101, 104, Jul. 2001, [Peer-reviewed]
  English, Scientific journal
• Prognostic significance of combined conventional and immunocytochemical cytology for peritoneal washings in endometrial carcinoma
  ML Luo; N Sakuragi; M Shimizu; K Seino; K Okamoto; M Kaneuchi; Y Ebina; K Okuyama; T Fujino; T Sagawa; S Fujimoto
  CANCER CYTOPATHOLOGY, 93, 2, 115, 123, Apr. 2001, [Peer-reviewed]
  English, Scientific journal
• Prenatal diagnosis of agnathia-holoprosencephaly: three-dimensional imaging by helical computed tomography
  Y Ebina; H Yamada; EH Kato; F Tanuma; S Shimada; K Cho; S Fujimoto
  PRENATAL DIAGNOSIS, 21, 1, 68, 71, Jan. 2001, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Insulin response patterns contribute to different perinatal risks in gestational diabetes
  H Yamada; EH Kato; R Tsuruga; Y Ebina; G Kobashi; T Sagawa; Z Makita; T Koike; S Fujimoto
  GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 51, 2, 103, 109, 2001, [Peer-reviewed]
  English, Scientific journal
• Recurrent pregnancy loss: Etiology of thrombophilia
  H Yamada; EH Kato; G Kobashi; Y Ebina; S Shimada; M Morikawa; T Yamada; N Sakuragi; S Fujimoto
  SEMINARS IN THROMBOSIS AND HEMOSTASIS, 27, 2, 121, 129, 2001, [Peer-reviewed]
  English, Scientific journal
• NK cell activity and subsets in women with a history of spontaneous abortion - Cause, number of abortions, and subsequent pregnancy outcome
  M Morikawa; H Yamada; EH Kato; S Shimada; Y Ebina; T Yamada; T Sagawa; G Kobashi; S Fujimoto
  GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 52, 3, 163, 167, 2001, [Peer-reviewed]
  English, Scientific journal
• Prognostic significance of peritoneal cytology in endometrial carcinoma: Application of immunocytochemistry for MOC-31
  ML Luo; N Sakuragi; M Shimizu; K Seino; K Okamoto; M Kaneuchi; Y Ebina; K Okuyama; T Fujino; T Sagawa; S Fujimoto
  FRONTIERS IN OBSTETRICS AND GYNECOLOGY, PROCEEDINGS, 49, 53, 2001, [Peer-reviewed]
  English, International conference proceedings
• Postpartum thyroid dysfunction in women with normal thyroid function during pregnancy
  M Sakaihara; H Yamada; EH Kato; Y Ebina; S Shimada; G Kobashi; M Fukushi; S Fujimoto
  CLINICAL ENDOCRINOLOGY, 53, 4, 487, 492, Oct. 2000, [Peer-reviewed]
  English, Scientific journal
• Prevention of lymphocyst formation following systematic lymphadenectomy
  R Yamamoto; T Saitoh; T Kusaka; Y Todo; M Takeda; K Okamoto; E Nomura; Y Ebina; M Kaneuchi; N Sakuragi; S Fujimoto
  JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 30, 9, 397, 400, Sep. 2000, [Peer-reviewed]
  English, Scientific journal
• Prevention of vaginal shortening following radical hysterectomy
  R Yamamoto; K Okamoto; Y Ebina; H Shirato; N Sakuragi; S Fujimoto
  BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 107, 7, 841, 845, Jul. 2000, [Peer-reviewed]
  English, Scientific journal
• Novel mutation (E113X) of antithrombin III gene (AT3) in a woman with gestational recurrent thrombosis
  H Yamada; N Hoshi; EH Kato; Y Ebina; T Kishida; T Sagawa; K Matsuno; S Fujimoto
  AMERICAN JOURNAL OF MEDICAL GENETICS, 91, 5, 348, 350, Apr. 2000, [Peer-reviewed]
  English, Scientific journal
• Factor XII deficiency in women with recurrent miscarriage
  H Yamada; EH Kato; Y Ebina; T Kishida; N Hoshi; G Kobashi; N Sakuragi; S Fujimoto
  GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 49, 2, 80, 83, 2000, [Peer-reviewed]
  English, Scientific journal
• Prevention of vaginal shortening following radical hysterectomy
  Ritsu Yamamoto; Kazuhira Okamoto; Yasuhiko Ebina; Hiroki Shirato; Noriaki Sakuragi; Seiichiro Fujimoto
  BJOG: An International Journal of Obstetrics and Gynaecology, 107, 7, 841, 845, 7, 2000, [Peer-reviewed]
  English, Scientific journal
• Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma
  Y Ebina; H Yamada; T Fujino; Furuta, I; N Sakuragi; R Yamamoto; M Katoh; M Oshimura; S Fujimoto
  INTERNATIONAL JOURNAL OF CANCER, 84, 5, 529, 532, Oct. 1999, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Fetal treatment of congenital heart block ascribed to anti-SSA antibody: Case reports with observation of cardiohemodynamics and review of the literature
  H Yamada; EH Kato; Y Ebina; M Moriwaki; R Yamamoto; Furuta, I; S Fujimoto
  AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 42, 4, 226, 232, Oct. 1999, [Peer-reviewed]
  English, Scientific journal
• A study on the lectin reactivity of alpha-fetoprotein produced by hepatoid adenocarcinomas and yolk sac tumors
  Ritsu Yamamoto; Yukio Wakui; Kazuhisa Taketa; Hiroshi Ishikura; Noriaki Sakuragi; Rifumi Hattori; Hirofumi Sato; Yasuhiko Ebina; Shinzo Nishi; Seiichiro Fujimoto
  Tumor Biology, 20, 4, 212, 217, 4, Jul. 1999, [Peer-reviewed]
  English, Scientific journal
• Malignant Brenner tumors of the ovary and tumor markers: Case reports
  R Yamamoto; M Fujita; M Kuwabara; M Sogame; Y Ebina; N Sakuragi; H Kato; S Fujimoto
  JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 29, 6, 308, 313, Jun. 1999, [Peer-reviewed]
  English, Scientific journal
• Hypocomplementemia correlates with intrauterine growth retardation in systemic lupus erythematosus
  Noriko Kobayashi; Hideto Yamada; Tatsuro Kishida; Emi-Hirayama Kato; Yasuhiko Ebina; Noriaki Sakuragi; Gen Kobashi; Akito Tsutsumi; Seiichiro Fujimoto
  American Journal of Reproductive Immunology, 42, 3, 153, 159, Blackwell Munksgaard, 1999, [Peer-reviewed]
  English, Scientific journal
• Fetal treatment of congenital heart block ascribed to anti-SSA antibody: Case reports with observation of cardiohemodynamics and review of the literature
  Hideto Yamada; Emi H. Kato; Yasuhiko Ebina; Masashi Moriwaki; Ritsu Yamamoto; Itsuko Furuta; Seiichiro Fujimoto
  American Journal of Reproductive Immunology, 42, 4, 226, 232, Blackwell Munksgaard, 1999, [Peer-reviewed]
  English, Scientific journal
• Passive immune thrombocytopenia in neonates of mothers with idiopathic thrombocytopenic purpura: Incidence and risk factors
  H Yamada; EH Kato; G Kobashi; T Kishida; Y Ebina; M Kaneuchi; S Suzuki; S Fujimoto
  SEMINARS IN THROMBOSIS AND HEMOSTASIS, 25, 5, 491, 496, 1999, [Peer-reviewed]
  English, Scientific journal
• Prenatal diagnosis and fetal therapy for congenital cytomegalovirus infection: a trial of intraperitoneal hyperimmunoglobulin injection.
  Yamada H; Negishi H; Ebina Y; Kato EH; Kobashi G; Sagawa T; Sakuragi N; Fujimoto S
  Virus Infection Seminar, 1, 27, 34, 1999, [Peer-reviewed]
• Cox multivariate regression models for estimating prognosis of patients with endometrioid adenocarcinoma of the uterine corpus who underwent thorough surgical staging
  M Nishiya; N Sakuragi; H Hareyama; Y Ebina; M Furuya; M Oikawa; R Yamamoto; T Fujino; S Fujimoto
  INTERNATIONAL JOURNAL OF CANCER, 79, 5, 521, 525, Oct. 1998, [Peer-reviewed]
  English, Scientific journal
• Lectin affinity electrophoresis in a yolk sac tumour in the vagina with yolk sac tumour-type glycoform of alpha fetoprotein
  R Yamamoto; K Taketa; Y Ebina; Y Cho; H Hareyama; N Sakuragi; S Makinoda; K Kobayashi; S Nishi; S Fujimoto
  JOURNAL OF CLINICAL PATHOLOGY, 50, 10, 856, 858, Oct. 1997, [Peer-reviewed]
  English, Scientific journal
• Peritoneal cytology and its prognostic value in endometrial carcinoma
  Y Ebina; H Hareyama; N Sakuragh; R Yamamoto; M Furuya; M Sogame; T Fujino; S Makinoda; S Fujimoto
  INTERNATIONAL SURGERY, 82, 3, 244, 248, Jul. 1997, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal

• 【不妊・不育症女性の合併症・併存疾患をどう扱う?】血栓性素因
  出口 雅士; 谷村 憲司; 蝦名 康彦; 山田 秀人, 産婦人科の実際, 69, 13, 1605, 1614, Dec. 2020
  金原出版(株), Japanese
• イリノテカン+シスプラチン療法が奏功した局所進行子宮頸部小細胞癌の一例
  安積 麻帆; 鈴木 嘉穂; 出口 雅士; 松本 培世; 長又 哲史; 高橋 良輔; 蝦名 康彦; 寺井 義人, 日本婦人科腫瘍学会雑誌, 38, 2, 193, 199, Apr. 2020
  (公社)日本婦人科腫瘍学会, Japanese
• 子宮頸部円錐切除術後フォローアップの現状と課題
  蝦名 康彦, 産婦人科の進歩, 71, 3, 287, 292, Aug. 2019, [Peer-reviewed], [Invited]
  「産婦人科の進歩」編集室, Japanese
• 卵巣癌初回治療におけるdose-dense TC療法とTC+bevacizumab併用療法の比較
  鈴木 嘉穂; 中筋 由紀子; 安積 麻帆; 高橋 良輔; 長又 哲史; 松本 培世; 出口 雅士; 蝦名 康彦; 寺井 義人, 日本婦人科腫瘍学会雑誌, 37, 3, 451, 451, Jun. 2019
  (公社)日本婦人科腫瘍学会, Japanese
• 卵巣癌・腹膜癌の術前化学療法時の診断において、腹腔鏡下生検と体腔液Cell block法の比較検討
  高橋 良輔; 鈴木 嘉穂; 中筋 由紀子; 安積 麻帆; 長又 哲史; 松本 培世; 出口 雅士; 蝦名 康彦; 寺井 義人, 日本婦人科腫瘍学会雑誌, 37, 3, 457, 457, Jun. 2019
  (公社)日本婦人科腫瘍学会, Japanese
• 子宮頸がんに対する放射線治療後不全骨折発症のリスクについての検討
  松本 培世; 鈴木 嘉穂; 安積 麻帆; 中筋 由紀子; 清水 真帆; 高橋 良輔; 長又 哲史; 蝦名 康彦; 出口 雅士; 寺井 義人, 日本婦人科腫瘍学会雑誌, 37, 3, 476, 476, Jun. 2019
  (公社)日本婦人科腫瘍学会, Japanese
• トラベクテジンの長期投与が可能であった平滑筋肉腫の二例
  長又 哲史; 蝦名 康彦; 安積 麻帆; 高橋 良輔; 松本 培世; 鈴木 嘉穂; 出口 雅士; 寺井 義人, 日本婦人科腫瘍学会雑誌, 37, 3, 525, 525, Jun. 2019
  (公社)日本婦人科腫瘍学会, Japanese
• 卵巣癌患者における治療前Prognostic nutritional indexと予後
  蝦名 康彦; 長又 哲史; 鈴木 嘉穂; 若橋 宣; 宮原 義也; 出口 雅士; 山田 秀人, 日本女性栄養・代謝学会誌, 25, 1, 49, 50, Jun. 2019
  日本女性栄養・代謝学会, Japanese
• 当院で経験した腹膜原発癌肉腫の2例
  中筋 由紀子; 鈴木 嘉穂; 長又 哲史; 安積 麻帆; 高橋 良輔; 松本 培世; 蝦名 康彦; 出口 雅士; 寺井 義人; 山田 秀人, 産婦人科の進歩, 71, 2, 230, 230, May 2019
  「産婦人科の進歩」編集室, Japanese
• 【産婦人科感染症の最前線】風疹,サイトメガロウイルス,パルボウイルスB19
  谷村 憲司; 蝦名 康彦; 山田 秀人, 日本産科婦人科学会雑誌, 71, 5, 643, 651, May 2019
  (公社)日本産科婦人科学会, Japanese
• 【産婦人科救急・当直対応マニュアル】婦人科編 症状・所見からみた疾患鑑別と病態把握 救急外来 不正性器出血が主訴のとき
  蝦名 康彦, 臨床婦人科産科, 73, 4, 26, 31, Apr. 2019
  (株)医学書院, Japanese
• 正常胎児と全奇胎の双胎(complete hydatidiform mole coexistent with a fetus)の3症例
  吉澤 ひかり; 蝦名 康彦; 今福 仁美; 鈴木 嘉穂; 若橋 宣; 宮原 義也; 出口 雅士; 山田 秀人, 産婦人科の進歩, 71, 1, 9, 16, Feb. 2019
  過去10年間に当科で経験した正常胎児と全奇胎の双胎(CHMCF)3例について報告した。CHMCFの診断週数は12〜14週で、2例は排卵誘発による妊娠であった。母体合併症は妊娠悪阻が1例、性器出血が3例であった。診断後、妊娠継続に関するリスクについて十分な説明を行ったところ、2例は妊娠中絶を希望したが、残りの1例は希望により妊娠継続をしていた。だが、臨床的侵入奇胎のため妊娠21週1日目で人工妊娠中絶となった。3例中2例では続発性疾患(奇胎後hCG存続症1例、臨床的侵入奇胎1例)を認め、化学療法にて寛解が得られた。, 「産婦人科の進歩」編集室, Japanese
• 不育症のトピックス 不育症とネオ・セルフ
  谷村 憲司; 笹川 勇樹; 今福 仁美; 森實 真由美; 出口 雅士; 蝦名 康彦; 荒瀬 規子; 荒瀬 尚; 齋藤 滋; 山田 秀人, 日本生殖医学会雑誌, 63, 3, 230, 230, Aug. 2018
  (一社)日本生殖医学会, Japanese
• 婦人科がん 最新の研究動向 子宮頸癌治療ガイドライン
  蝦名康彦; 三上幹男, 日本臨床, 76, 増2, 259, 261, Mar. 2018, [Invited]
  Japanese, Introduction commerce magazine
• サイトメガロウイルス母子感染の対策
  山田秀人; 森岡一朗; 出口雅士; 谷村憲司; 平久進也; 森實真由美; 蝦名康彦; 峰松俊夫, 日本産婦人科感染症学会誌, 2, 1, 2, 12, 2018
  (一社)日本産婦人科感染症学会, Japanese, Introduction scientific journal
• TORCH症候群の現状と問題点 (特集 TORCH症候群 : 母子感染における問題点)
  山田 秀人; 蝦名 康彦, 日本医事新報, 4872, 26, 32, 09 Sep. 2017
  日本医事新報社, Japanese
• A case of non-puerperal incomplete uterine inversion caused by submucous leiomyoma
  SHI Yutoku; EBINA Yasuhiko; MIYAHARA Yoshiya; YAMADA Hideto, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 69, 2, 126, 130, May 2017
  

  Synopsis The frequency of non-puerperal uterine inversion is rare. Non-puerperal incomplete uterine inversion was diagnosed in a 52-year-old woman (gravida 2, para 2, not yet menopausal). She was diagnosed with uterine myoma at 47 years old. She visited a GYN clinic because of irregular vaginal bleeding at 50 years old, and repeated GnRHa treatment was selected. However, the size of the uterine myoma could not be reduced, and the patient was referred to our hospital for operative treatment. The chief complaint at the initial visit was a generous amount of vaginal discharge. The diagnosis of non-puerperal incomplete uterine inversion was made according to MRI findings of an inverted fundus and prolapsed submucous myoma in the vagina. Abdominal total hysterectomy and bilateral fallopian tubal resection were performed. The pathological diagnosis was submucous uterine leiomyoma. The postoperative course was uneventful and the symptom of discharge disappeared. [Adv Obstet Gynecol, 69 (2) : 126-130, 2017 (H29.5)]

  , THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, Japanese, Report scientific journal
• Two cases of polypoid endometriosis
  浦瀬 靖代; 北島 一宏; 上野 嘉子; 前田 哲雄; 高橋 哲; 蝦名 康彦; 原 重雄; 杉村 和朗, 臨床放射線, 62, 5, 719, 723, May 2017
  金原出版, Japanese
• 胎児を守るためのウイルス感染対策 (特集 感染対策の視点で考える乳幼児のウイルス感染症)
  出口 雅士; 森實 真由美; 蝦名 康彦; 山田 秀人, チャイルドヘルス, 20, 5, 346, 351, May 2017
  診断と治療社, Japanese
• Integrated FDG-PET/MRI for whole-body staging in patients with recurrent gynecological cancer
  Kazuhiro Kitajima; Munenobu Nogami; Satoru Takahashi; Yoshiko Ueno; Yasuhiko Ebina; Kazuhiro Kubo; Utaru Tanaka; Keitaro Sofue; Takeaki Ishihara; Yuichi Wakabayashi; Kazunari Ishii; Kazuro Sugimura, JOURNAL OF NUCLEAR MEDICINE, 58, May 2017
  English, Summary international conference
• 卵管癌との鑑別に苦慮した活動性卵管炎の1例
  末永 裕子; 前田 哲雄; 上野 嘉子; 高橋 哲; 杉本 幸司; 杉村 和朗; 蝦名 康彦; 山田 秀人; 糸口 直江; 原 重雄, Japanese Journal of Radiology, 35, Suppl., 45, 45, Feb. 2017
  (公社)日本医学放射線学会, Japanese
• サイトメガロウイルス (特集 周産期のウイルス感染症) -- (妊娠・分娩・産褥時の対応)
  山田 秀人; 谷村 憲司; 出口 雅士; 蝦名 康彦; 森岡 一朗; 峰松 俊夫, 周産期医学, 47, 2, 213, 218, Feb. 2017
  東京医学社, Japanese
• 【多彩なヘルペスウイルス感染症-その診断と治療up to dateとして-】 ヘルペスウイルス感染症の診断と治療 産婦人科領域のヘルペスウイルス感染症 性器ヘルペス
  蝦名康彦; 山田秀人, Modern Physician, 36, 12, 1289, 1293, Dec. 2016, [Invited]
  (株)新興医学出版社, Japanese, Introduction commerce magazine
• 腹腔鏡下性腺摘除術を施行した完全型アンドロゲン不応症の1例
  白川 得朗; 蝦名 康彦; 豊永 絢香; 小嶋 伸恵; 鈴木 嘉穂; 若橋 宣; 市田 耕太郎; 宮原 義也; 森田 宏紀; 山田 秀人, 日本産科婦人科内視鏡学会雑誌, 32, 1, 255, 259, Nov. 2016, [Peer-reviewed]
  

    We present a case of complete androgen insensitivity syndrome (CAIS) treated by laparoscopic gonadectomy. Case: A 19-year-old phenotypical female, who complained of primary amenorrhea, was referred to our hospital. Physical examination revealed the absence of the proximal vagina and female external genitalia. Pelvic magnetic resonance imaging revealed bilateral pelvic masses, and the absence of both the uterus and the vagina. Hormonal examination revealed elevated serum testosterone level at 8.3 ng/mL (normal values in female adults, 0.06-0.86 ng/mL). Her karyotype was 46,XY. Therefore, we diagnosed complete CAIS. She underwent laparoscopic gonadectomy. Histopathological examination showed immature seminiferous tubules and Leydig cells in both gonads. Her postoperative course was uneventful and she was discharged on postoperative day 5. She is being treated with and will continue to receive hormone replacement. Care for patients with CAIS needs to be individualized, flexible, and holistic because they are often raised socially as women. Laparoscopic gonadectomy in patients with CAIS is useful, because it is less invasive and has improved cosmetic results compared with open surgery.

  , (一社)日本産科婦人科内視鏡学会, Japanese
• 免疫学的異常と免疫グロブリン療法 (特集 不育症Up to Date)
  山田 秀人; 出口 雅士; 蝦名 康彦, 産科と婦人科, 83, 5, 535, 539, May 2016
  診断と治療社, Japanese
• 特集 伝染性紅斑を見直す ４ 母子感染の実態～全国産科施設を対象とした実態調査
  蝦名康彦; 平久進也; 森岡一朗; 出口雅士; 森實真由美; 山田秀人, 小児科, 56, 1867, 1873, Nov. 2015, [Peer-reviewed], [Invited]
  Japanese, Introduction scientific journal
• 伝染性紅斑流行時の妊婦健診における留意点について
  蝦名康彦, 産婦の進歩, 67, 419, 420, Nov. 2015, [Peer-reviewed], [Invited]
  Japanese, Introduction scientific journal
• 母子感染アップデート わが国におけるパルボウイルスB19母子感染の実態調査
  蝦名康彦, 医学のあゆみ, 253, 1245, 1249, Jun. 2015, [Invited]
  Japanese, Introduction scientific journal
• 新生児尿スクリーニングと抗ウイルス薬治療導入後の症候性先天性サイトメガロウイルス感染児の後遺症発生率
  森岡 一朗; 西田 浩輔; 香田 翼; 岩谷 壮太; 出口 雅士; 谷村 憲司; 平久 進也; 蝦名 康彦; 船越 徹; 大橋 正伸; 飯島 一誠; 山田 秀人, 日本産婦人科感染症学会学術講演会プログラム・抄録集, 32回, 37, 37, May 2015
  (一社)日本産婦人科感染症学会, Japanese
• 症候性先天性サイトメガロウイルス感染児の聴性脳幹反応に対する抗ウイルス薬治療の効果と問題点
  森岡 一朗; 西田 浩輔; 香田 翼; 岩谷 壮太; 出口 雅士; 谷村 憲司; 平久 進也; 蝦名 康彦; 飯島 一誠; 山田 秀人, 日本産婦人科感染症学会学術講演会プログラム・抄録集, 32回, 38, 38, May 2015
  (一社)日本産婦人科感染症学会, Japanese
• 周産期の炎症・感染への挑戦 先天性サイトメガロウイルス感染の効果的な周産期管理法の確立を目指して
  森岡 一朗; 平久 進也; 蝦名 康彦; Tanimura Kenji; Deguchi Masashi; 園山 綾子; 峰松 俊夫; 井上 直樹; 飯島 一誠; 山田 秀人, 日本周産期・新生児医学会雑誌, 50, 別冊, 22, 23, Jan. 2015
  Japanese, Meeting report
• A case of large parasitic myoma daiagnosed seven years after laparoscopic myomectomy that developed in the pelvic cavity and spread to the retroperitoneal space
  NAGAMATA SATOSHI; EBINA YASUHIKO; MIYAHARA YOSHIYA; NIIYA KIYOSHI; UENO YOSHIKO; KITAJIMA KAZUHIRO; KAWAKAMI FUMI; YAMADA HIDETO, 産婦人科の進歩, 66, 4, 361, 366, Oct. 2014
  47歳女。39歳時に腹腔鏡下子宮筋腫核出術、40歳時に甲状腺乳頭癌に対して甲状腺摘出術の既往があった。無月経、不正性器出血で受診した際に、骨盤内から後腹膜腔へ発達する巨大な腫瘍を指摘された。PET-CTでは腫瘍部位にFDGの有意な集積を認めず、有茎性漿膜下筋腫を疑った。原発不明腫瘍の診断で手術を施行した。病理組織では、腹腔鏡下子宮筋腫核出術の既往があることから、腹腔鏡下筋腫核出術後に発生した医原性parasitic myomaと推察した。当時の手術記録を取り寄せたところ、子宮後壁頸部近くの97mm大の筋腫を核出後、モルセレーターを使用し体外に摘出していた。その際の残存筋腫が栄養血管を獲得しながら発育し、後腹膜腔にまで達する巨大なparasitic myomaとなったと推測された。腫瘍および子宮頸部・体部細胞診において悪性所見は認めず、不正性器出血に関しては閉経周辺期の機能性子宮出血と考えられた。, 「産婦人科の進歩」編集室, Japanese
• 卵巣奇形腫に対して発症早期に腹腔鏡手術を施行し経過良好であった抗NMDAR抗体関連脳炎の1症例
  蝦名康彦; 山崎友維; 白川得朗; 牧原夏子; 宮原義也; 新谷潔; 中林幸士; 松岡正造; 上中建; 横田一郎; 苅田典生; 田中惠子; 山田秀人, 日本産科婦人科内視鏡学会雑誌, 29, 2, 469, 474, Mar. 2014, [Peer-reviewed], [Lead author, Corresponding author]
  症例は35歳女で、職場で気分高揚・多弁となり、躁状態は悪化して奇異で滅裂な言動が増加し、さらに傾眠傾向、独語、手足の振戦、流涎が出現し、無呼吸発作も頻発した。骨盤MRIで右卵巣の一部に長径17mmの脂肪抑制を受けるT1 highの部分を認め、頭部MRIでは両側側頭内側皮質に淡い高信号域を認めた。右成熟嚢胞性奇形腫を伴う抗N-methyl-D-aspartate受容体(NMDAR)抗体関連脳炎を疑い、腹腔鏡下右付属器摘出術を施行した。摘出卵巣は5×3×2.5cmで、神経成分や皮膚、軟骨の成分を認めたが未熟成分や悪性所見はなく、成熟嚢胞性奇形腫と診断した。髄液検査では抗NMDAR抗体陽性が確認された。術後は自律神経系の障害がみられ、ステロイドパルス療法、中枢性低換気に対する気管切開、血漿交換、大量免疫グロブリン療法を施行し、徐々に意思疎通が可能となり、第97病日にリハビリのため転院した。発症から8ヵ月で職場復帰を果たした。, (一社)日本産科婦人科内視鏡学会, Japanese
• 一般小児科医のための新生児対応パーフェクトガイド II.母子感染が疑われる児への対応 サイトメガロウイルス抗体・トキソプラズマ抗体
  森岡一朗; 山田秀人; 平久進也; 蝦名康彦; 出口雅士; 香田翼; 飯島一誠, 小児科診療, 77, 3, 347, 350, 01 Mar. 2014
  Japanese
• 卵巣奇形腫における悪性転化の術前予測についての検討
  牧原夏子; 蝦名康彦; 山崎友維; 今福仁美; 生橋義之; 松岡正造; 宮原義也; 新谷潔; 森田宏紀; 山田秀人, 日本産科婦人科学会雑誌, 66, 2, 627, 01 Feb. 2014
  Japanese
• 読み方がわかる!説明できる!産科の臨床検査ディクショナリー
  青木茂; 秋野亮介; 新垣達也; 池田智明; 市塚清健; 伊東宏晃; 蝦名康彦; 太田創; 大槻克文; 大野泰正; 大場智洋; 大原玲奈; 奥田美加; 奥山亜由美; 小畠真奈; 折坂勝; 葛西路; 倉澤健太郎; 佐藤昌司; 佐村修; 下平和久; 関沢明彦; 平久進也; 高橋恒男; 瀧田寛子; 塚原優己; 出口雅士; 徳中真由美; 中田雅彦; 中田雅彦; 仲村将光; 西田浩子; 長谷川潤一; 長谷川良実; 花岡正智; 濱田尚子; 濱田洋実; 松岡隆; 松本美奈子; 三科美幸, ペリネイタルケア, 290P, 10 Jan. 2014
  Japanese
• 臨床研究の成果を実地臨床へ生かそう―産科編 我が国における多施設共同研究の現状―サイトメガロウイルス―
  山田秀人; 森岡一朗; 平久進也; 谷村憲司; 出口雅士; 蝦名康彦, 周産期医学, 43, 10, 1295, 1299, 10 Oct. 2013
  Japanese
• 子宮留膿腫を契機に発見された子宮体部原発扁平上皮癌の1症例
  牧原夏子; 蝦名康彦; 出口可奈; 白川得朗; 宮原義也; 上野嘉子; 前田哲雄; 川上史; 原重雄; 山田秀人, 日本婦人科腫よう学会雑誌, 31, 4, 1062, 1067, Oct. 2013
  (公社)日本婦人科腫瘍学会, Japanese
• 子宮頸癌放射線治療の新展開 高齢子宮頸癌患者に対する根治的放射線治療の経験
  吉田 賢史; Miyawaki Daisuke; Ejima Yasuo; 西村 英輝; 岡本 欣晃; 蝦名 康彦; Sasaki Ryohei, 日本婦人科腫瘍学会雑誌, 31, 3号, 412, 412, Jun. 2013
  (公社)日本婦人科腫瘍学会, Japanese, Meeting report
• 検査値を読む2013 28章 性腺・胎盤検査 ヒト絨毛性ゴナドトロピン
  蝦名康彦; 山田秀人, 内科, 111, 6, 1546, 01 Jun. 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 神戸大学における先天性CMV感染児の臨床像とフォローアップの現況
  森岡一朗; 柴田暁男; 三輪明弘; 横山直樹; 園山綾子; 平久進也; 谷村憲司; 蝦名康彦; 峰松俊夫; 井上直樹; 飯島一誠; 山田秀人, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成23-24年度 総合研究報告書, 109, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 サイトメガロウイルス母子感染対策のための妊婦教育効果の検討,ならびに妊婦スクリーニング体制の構築
  山田秀人; 古谷野伸; 岡明; 井上直樹; 森岡一朗; 森内浩幸; 吉川哲史; 伊藤裕司; 浅野仁覚; 五石圭司; 三牧正和; 蝦名康彦; 谷村憲司; 平久進也; 園山綾子; 出口雅士, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成23-24年度 総合研究報告書, 31, 53, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 7.全国妊婦健診施設を対象とした妊婦感染症スクリーニングと先天性感染の実態調査
  平久進也; 谷村憲司; 園山綾子; 蝦名康彦; 森岡一朗; 山田秀人, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成24年度 総括・分担研究報告書, 86, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 CMV IgM陽性妊婦における先天性CMV感染の発生予測
  園山綾子; 蝦名康彦; 谷村憲司; 森岡一朗; 森實真由美; 平久進也; 峰松俊夫; 山田秀人, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成23-24年度 総合研究報告書, 113, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 サイトメガロウイルス母子感染対策のための妊婦教育効果の検討,ならびに妊婦スクリーニング体制の構築
  山田秀人; 古谷野伸; 岡明; 井上直樹; 森岡一朗; 森内浩幸; 吉川哲史; 伊藤裕司; 浅野仁覚; 三牧正和; 蝦名康彦; 平久進也; 出口雅士, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成24年度 総括・分担研究報告書, 29, 47, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 8.母体血CMV IgG avidity測定による先天性感染の発生予知
  蝦名康彦; 森上聡子; 平久進也; 谷村憲司; 森岡一朗; 園山綾子; 峰松俊夫; 山田秀人, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成24年度 総括・分担研究報告書, 87, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 妊婦におけるCMV母子感染に関する知識レベル
  森岡一朗; 園山綾子; 平久進也; 谷村憲司; 蝦名康彦; 山田秀人, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成23-24年度 総合研究報告書, 114, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 9.先天性CMV感染に対する免疫グロブリン胎児治療
  山田秀人; 平久進也; 谷村憲司; 蝦名康彦; 森岡一朗, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成24年度 総括・分担研究報告書, 88, 2013
  Japanese
• 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討,妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 6.母子感染に関する妊婦の知識調査
  森岡一朗; 園山綾子; 平久進也; 足立陽子; 谷村憲司; 蝦名康彦; 山田秀人, 先天性サイトメガロウイルス感染症対策のための妊婦教育の効果の検討、妊婦・新生児スクリーニング体制の構築及び感染新生児の発症リスク同定に関する研究 平成24年度 総括・分担研究報告書, 85, 2013
  Japanese
• A pregnant case with absence of a right pulmonary artery accompanied by hemoptysis.
  UENAKA MIZUKI; TAIRAKU SHIN'YA; SONOYAMA AYAKO; HAZAMA RYOICHI; TANIMURA KENJI; EBINA YASUHIKO; MORITA HIROKI; YAMASAKI MINEO; YAMADA HIDETO, 日本周産期・新生児医学会雑誌, 48, 4, 976, 980, 15 Dec. 2012
  Japanese
• Ectopic ovary found in laparoscopic surgery : case report
  YAMASAKI Yui; EBINA Yasuhiko; YONE Atsuko; TOMIYAMA Youko; OKADA Tomoko; FUJITA Ichiro; SOUDA Hiroo; YAMADA Hideto, JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY, 28, 1, 378, 381, Aug. 2012
  An ectopic ovary is a very rare condition. A 27-year-old woman underwent laparoscopy because of a dermoid cyst on the right ovary and was found to have a cystic mass in the mesentery of the sigmoid colon. Despite thorough inspection, her left ovary was not found in the usual place. The left infundibulopelvic ligament was also nonexistent. Pathological examination revealed ovarian stromata in the cystic mass in the mesentery of the sigmoid colon., Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy, Japanese
• 産科外来診療フローチャート―妊婦管理のすべて―合併症妊娠の評価と管理 全身性エリテマトーデスと抗リン脂質抗体症候群
  山田秀人; 谷村憲司; 前澤陽子; 蝦名康彦, 産婦人科の実際, 61, 7, 1043, 1049, 01 Jul. 2012
  Japanese
• 妊婦 母子感染の管理 2)トキソプラズマ,サイトメガロウイルス,パルボウイルスB19
  山田秀人; 谷村憲司; 蝦名康彦, 臨床婦人科産科, 66, 5, 166, 174, 20 Apr. 2012
  Japanese
• Radical hysterectomy and preservation of physiological functions in cervical cancer
  EBINA Yasuhiko, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 64, 2, 215, 220, 2012, [Peer-reviewed], [Invited]
  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, Japanese
• 不育症 最前線 不育症に対する免疫グロブリン療法
  山田秀人; 前澤陽子; 武田真光; 谷村憲司; 陌間亮一; 蝦名康彦, 産婦人科の実際, 60, 10, 1473, 1480, 01 Oct. 2011
  金原出版, Japanese
• 産婦人科の遺伝医療と遺伝カウンセリング 周産期感染におけるカウンセリング―トキソプラズマとサイトメガロウイルス―
  山田秀人; 谷村憲司; 森岡一朗; 森實真由美; 園山綾子; 平久進也; 蝦名康彦; 井上直樹; 古谷野伸; 峰松俊夫, 産婦人科の実際, 60, 9, 1309, 1321, 01 Sep. 2011
  Japanese
• The analysis of deep vein thrombosis in women with ovarian tumors before surgery
  TAKEI TOMONOBU; NAKABAYASHI KOJI; TAKEMURA NAOYA; MAKIHARA NATSUKO; SUZUKI KAHO; HAZAMA RYOICHI; MORIZANE MAYUMI; DEGUCHI MASASHI; MIYAHARA YOSHIYA; EBINA YASUHIKO; YOSHIDA SHIGEKI; YAMADA HIDETO, 産婦人科の進歩, 63, 3, 271, 276, 01 Aug. 2011
  This study was conducted to establish the strategy for diagnosis of deep vein thrombosis (DVT)in women with ovarian tumors before surgery in Kobe University Hospital. Medical charts of 193 women with ovarian tumors who had undergone surgery in Kobe University Hospital between January 2006 and June 2010 were systemically reviewed. Pathological examinations identified 115 cases with benign ovarian tumors, 15 cases with borderline malignancy and 63 cases with malignant ovarian tumors. Clinical and laboratory data were compared between patients diagnosed as having DVT and those with no evidence of DVT. Venous ultrasound imaging of the lower extremity was performed in 32 out of 193 patients. 18 out of 32 patients were diagnosed as having DVT before surgery, including 5 cases with benign ovarian tumors, 2 cases with borderline malignancy, and 11 cases with malignant ovarian tumors. The statistical analyses were performed between DVT patients and non-DVT patients in terms of benign-malignancy, ages, with or without symptoms, tumor maximum diameters, plasma D-dimer levels and BMI. The incidence of DVT was significantly higher in patients with malignant ovarian tumors compared with those with benign ovarian tumors. The incidence of DVT was not correlated with ages. The symptom such as limb pains, edema in the lower extremity clearly indicated the DVT existence compared with no symptom. The tumor maximum diameters had no significant differences in between DVT patients and non-DVT patients. But plasma D-dimer levels were significantly higher in patients with DVT than in those without DVT. Plasma D-dimer levels were found to be more than 3.0 μg/ml in all 18 cases with DVT. 12 out of 18 cases with DVT had symptoms. However, venous ultrasound imaging of the lower extremity demonstrated no findings of DVT in 6 patients who had both limb pains and plasma D-dimer levels less than 3.0μg/ml. In conclusion, the diagnosis of DVT by venous ultrasonography should be done in patients with ovarian tumors when their plasma D-dimer levels were at least more than 3.0μg/ml. [Adv Obstet Gynecol, 63(3) : 271-276, 2011 (H23.8)], THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, Japanese
• パルボウイルス感染 (特集 周産期の血液をめぐる話題--母体・胎児編) -- (胎児の血液異常)
  蝦名康彦; 谷村憲司; 山田秀人, 周産期医学, 41, 8, 1081, 1085, Aug. 2011, [Peer-reviewed], [Invited], [Lead author, Corresponding author]
  東京医学社, Japanese
• 周産期におけるサイトメガロウイルス対策
  Yamada Hideto; Tanimura Kenji; Morioka Ichiro; Morizane Mayumi; Tairaku Shinya; Ebina Yasuhiko, 日本産婦人科感染症研究会学術講演会記録集, 29号, 28, 36, Jun. 2011
  Japanese, Introduction scientific journal
• 円錐切除後子宮頸管狭窄に対するナイチノールステント留置の試み
  前田 悟郎; 首藤 聡子; 木川 聖美; 三田村 卓; 保坂 昌芳; 武田 真人; 蝦名 康彦; 渡利 英道; 金内 優典; 工藤 正尊; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 55, 1, 154, 155, Mar. 2011
  北海道産科婦人科学会, Japanese
• 細胞診陽性者におけるヒト・パピローマ・ウイルス(HPV)型分析の有用性および新しい経過観察指針作成について
  藤田 博正; 佐々木 隆之; 保坂 昌芳; 蝦名 康彦; 渡利 英道; 櫻木 範明, 北海道産科婦人科学会会誌, 55, 1, 153, 154, Mar. 2011
  北海道産科婦人科学会, Japanese
• 当科で子宮頸癌に対して施行した腹腔鏡下広汎子宮全摘(LRH)および骨盤リンパ節郭清の安全性や広汎性についての検討
  保坂 昌芳; 工藤 正尊; 森脇 征史; 三田村 卓; 加藤 達矢; 首藤 聡子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本産科婦人科内視鏡学会雑誌, 26, 1, 65, 65, Jul. 2010
  (一社)日本産科婦人科内視鏡学会, Japanese
• Feasibility of endoscopic radical and modified radical hysterectomy combined with pelvic lymphadenectomy
  HOSAKA Masayoshi; KUDO Masataka; AKASHI Daisuke; MITAMURA Takashi; KATO Tatsuya; MORIWAKI Masashi; SUDO Satoko; TAKEDA Mahito; EBINA Yasuhiko; WATARI Hidemichi; KANEUCHI Yoshinori; SAKURAGI Noriaki, JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY, 25, 2, 432, 437, Dec. 2009
  <B>Objectives:</B> The purpose of this study was to determine the feasibility and radicality of endoscopic radical hysterectomy (ERH) and endoscopic modified radical hysterectomy (EmRH) combined with pelvic lymphadenectomy (ELND) in invasive cervical cancer patients.<BR><B>Methods:</B> Five patients with invasive cervical cancer underwent ERH or EmRH between May 2003 and March 2007 at Hokkaido University Hospital. Two patients with stage I a adenocarcinoma underwent an EmRH, and two patients with stage I b1 and one patient with stage II a underwent an ERH. All patients gave their informed consent to this experimental procedure before surgery.<BR><B>Results:</B> The median age of patients was 39 years (range, 33-45 years), and the median body mass index was 20.2 kg/m<SUP>2</SUP> (range, 18.5-23.7 kg/m<SUP>2</SUP>). The maximum tumor diameter was 20mm in 1 patient, and ≤10mm in 4 patients. The pathologic subtype was squamous cell carcinoma in 2 patients, and adenocarcinoma in 3 patients. The median operative time was 734 min (range, 583-974 min), the median blood loss was 890 ml(range, 280-2650 ml), the median number of lymph nodes removed was 77 (range, 47-103), and the median length of vaginal cuff removed was 20mm(range, 10-25mm). The median duration of hospitalization post-operatively was 16 days (range, 13-23 days). A post-surgical infection occurred in one patient, but no severe complications were noted. There were no relapses after a mean follow-up period of 31.8 months (range, 15-71 months).<BR><B>Conclusions:</B> An ERH or EmRH with ELND is feasible and might be beneficial for early invasive cervical cancer., Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy, Japanese
• 婦人科系
  保坂 昌芳; 蝦名 康彦; 木川 聖美; 三田村 卓; 加藤 達矢; 首藤 聡子; 武田 真人; 渡利 英道; 金内 優典; 櫻木 範明, 日本臨床細胞学会北海道支部会報, 18, 58, 60, Sep. 2009
  北海道臨床細胞学会, Japanese
• 卵巣癌のリスク因子 (今月の臨床 婦人科がん検診) -- (卵巣がん検診)
  蝦名康彦; 櫻木範明, 臨床婦人科産科, 63, 9, 1204, 1211, Sep. 2009
  医学書院, Japanese
• 上皮性卵巣癌におけるp53変異とその予後に与える影響(Mutations of p53 in epithelial ovarian cancers and its effect on prognosis)
  鈴木 友希子; 多田 光宏; 金内 優典; 蝦名 康彦; 渡利 英道; 半田 康; 加藤 秀則; 櫻木 範明; 浜田 淳一; 守内 哲也, 日本癌学会総会記事, 68回, 329, 329, Aug. 2009
  日本癌学会, English
• 【子宮疾患・子宮内膜症の臨床 基礎・臨床研究のアップデート】 感染症・炎症性疾患 子宮腟部びらん
  金内 優典; 武田 真人; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本臨床, 67, 増刊5 子宮疾患・子宮内膜症の臨床, 335, 338, Aug. 2009
  (株)日本臨床社, Japanese
• 子宮頸癌における北大式系統的自律神経温存広汎子宮全摘術後の膀胱機能について
  保坂 昌芳; 藤堂 幸治; 小田 泰也; 三田村 卓; 加藤 達矢; 首藤 聡子; 武田 真人; 蝦名 康彦; 渡利 英道; 金内 優典; 櫻木 範明, 産婦人科の実際, 58, 8, 1227, 1232, Aug. 2009
  著者らが広汎子宮全摘術を行った子宮頸癌患者で、少なくとも片側の自律神経膀胱枝を温存できた60例を温存群、両側とも温存できなかった5例を非温存群とし、術前術後の尿流動態検査(UDS)用いた膀胱機能を比較検討した。その結果、最大蓄尿時膀胱コンプライアンス、最大尿流速度、排尿時最大腹圧、排尿時最大排尿筋圧、残尿のいずれも、温存群が非温存群と比べ有意に良好であった。, 金原出版(株), Japanese
• Cyr61高発現とリンパ節転移は子宮体癌の独立予後因子である
  渡利 英道; 田中 理恵子; 三田村 卓; 加藤 達矢; 保坂 昌芳; 首藤 聡子; 武田 真人; 蝦名 康彦; 金内 優典; 工藤 正尊; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 27, 3, 282, 282, Jun. 2009
  (公社)日本婦人科腫瘍学会, Japanese
• 卵巣癌に対するパクリタキセル胸腔内投与時の薬物動態
  三田村 卓; 保坂 昌芳; 首藤 聡子; 武田 真人; 蝦名 康彦; 渡利 英道; 金内 優典; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 27, 3, 291, 291, Jun. 2009
  (公社)日本婦人科腫瘍学会, Japanese
• 系統的自律神経温存広汎子宮全摘出術 北海道大学術式
  金内 優典; 保坂 昌芳; 藤堂 幸治; 三田村 卓; 加藤 達矢; 首藤 聡子; 武田 真人; 蝦名 康彦; 渡利 英道; 櫻木 範明, 産婦人科治療, 98, 6, 1026, 1033, Jun. 2009
  (株)永井書店, Japanese
• 子宮頸癌におけるリンパ節転移例の予後因子についての検討
  小島 崇史; 保坂 昌芳; 三田村 卓; 森脇 征史; 原 洋子; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 53, 1, 51, 52, Jan. 2009
  北海道産科婦人科学会, Japanese
• 術前化学療法を施行した子宮頸癌症例におけるアポトーシス抑制蛋白clusterinの発現と治療反応性および予後因子との関連
  渡利 英道; 鹿沼 達哉; 大田 陽子; 三田村 卓; 加藤 達矢; 保坂 昌芳; 藤堂 幸治; 首藤 聡子; 武田 真人; 蝦名 康彦; 峯岸 敬; 櫻木 範明, 日本癌治療学会誌, 43, 2, 814, 814, Oct. 2008
  (一社)日本癌治療学会, Japanese
• 【婦人科がん診療のリスクマネージメント】手術療法の問題点 子宮頸癌の手術
  蝦名 康彦; 三田村 卓; 加藤 達矢; 保坂 昌芳; 首藤 聡子; 武田 真人; 渡利 英道; 金内 優典; 工藤 正尊; 櫻木 範明, 産婦人科の実際, 57, 11, 1726, 1733, Oct. 2008, [Invited]
  金原出版(株), Japanese
• 雄性化破綻メカニズムとエピジェネティクス
  三觜 友子; 割田 克彦; 菅原 照夫; 田渕 圭章; 松本 由樹; 三木 崇範; 石原 可奈; 谷田 任司; 蝦名 康彦; 櫻木 範明; 横山 俊史; 竹内 義喜; 北川 浩; 星 信彦, 日本獣医学会学術集会講演要旨集, 146回, 148, 148, Sep. 2008
  (公社)日本獣医学会, Japanese
• 当科における浸潤子宮頸癌に対する鏡視下手術
  工藤 正尊; 保坂 昌芳; 森脇 征史; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 水上 尚典; 櫻木 範明, 産婦人科手術, 19, 179, 179, Aug. 2008
  (株)メジカルビュー社, Japanese
• 広汎子宮全摘術後の持続的な蓄尿コンプライアンス低下に影響を及ぼす因子の解析
  藤堂 幸治; 森脇 征史; 保坂 昌芳; 原 洋子; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 櫻木 範明, 日本外科系連合学会誌, 33, 4, 711, 711, Aug. 2008
  日本外科系連合学会, Japanese
• Radical hysterectomy and preservation of physiological functions in cervical cancer
  櫻木範明; 森脇征史; 蝦名康彦, 産婦人科治療, 97, 2, 139, 143, Aug. 2008
  永井書店, Japanese
• 当科で子宮頸癌に対して施行した腹腔鏡下広汎子宮全摘(LRH)および骨盤リンパ節郭清の5例について
  保坂 昌芳; 工藤 正尊; 森脇 征史; 三田村 卓; 加藤 達矢; 首藤 聡子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本産科婦人科内視鏡学会雑誌, 24, 1, 123, 123, Jul. 2008
  (一社)日本産科婦人科内視鏡学会, Japanese
• Total Laparoscopic Myomectomy : Application for Uterine Submucosal Myoma
  MORIWAKI Masashi; KUDO Masataka; SUDO Satoko; NISHI Shinya; KATO Tatsuya; WADA Shinichiro; MITSUBE Kenrokuro; HOSAKA Masayoshi; TODO Yukiharu; EBINA Yasuhiko; WATARI Hidemichi; OKOUCHI Toshihiro; MINAKAMI Hisanori; SAKURAGI Noriaki, JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY, 24, 1, 204, 208, Jul. 2008
  Background: Submucosal myoma has been treated with hysteroscopic transcervical resection (TCR) . However, in cases of unstalked submucosal myoma over 3cm in diameter, TCR could lead to not only extended operation time but also extensive thermal damage on endometrium by electrocoagulation. In this study, we validated the feasibility and utility of total Laparoscopic approach for submucosal myoma treatment.<BR>Materials and Methods: Total laparoscopic myomectomy (TLM) was performed on 12 women with submucosal myoma. Our TLM procedure was as follows: a balloon catheter was detained in the uterine cavity to evaluate the degree of submucosal projection by sonohysterography. Culdotomy was performed to set acrylic vaginal pipe into intraperitoneal cavity as a larger access port. After intramyometrial injection of vasopressin, a transverse incision was made to extract myomas. As myomectomy progressed, endometrium filled with indigocarmine through a detained balloon catheter appeared transparent-blue bulge, which helped easy recognition of endometrial injury. Uterine wall was sutured layer by layer without tucking the endometrium into myometrium. The enucleated nodules were removed via a vaginal pipe.<BR>Results: The median size of dominant submucosal myomas was 5cm, the median blood loss was 120ml and the median operating time was 162 minutes. There was no correlation between the degree of submucosal projection and endometrial defect. Minimal endometrial damage was observed and one of 3 infertile patients was pregnant after surgery.<BR>Conclusion: TLM was feasible in the cases of submucosal myoma as well as intramural and subserosal myomas., JAPAN SOCIETY OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY AND MINIMALLY INVASIVE THERAPY, Japanese
• 肺動脈に進展した子宮筋腫術後のintravenous leiomyomatosisの1例
  小田 泰也; 蝦名 康彦; 原 洋子; 保坂 昌芳; 小林 範子; 藤堂 幸治; 荒木 直人; 武田 真人; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明; 日下 剛, 日本産科婦人科学会東北連合地方部会誌, 55, 62, 62, Jun. 2008
  日本産科婦人科学会-東北連合地方部会, Japanese
• 後腹膜に発生し付属器腫瘍との鑑別を要したmalignant peripheral sheath tumorの1例
  荒木 直人; 武田 真人; 小田 泰也; 保坂 昌芳; 小林 範子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 55, 70, 70, Jun. 2008
  日本産科婦人科学会-東北連合地方部会, Japanese
• Docetaxel/Gemcitabine療法が奏功した再発子宮内膜間質肉腫の1例
  中谷 真紀子; 蝦名 康彦; 森脇 征史; 保坂 昌芳; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 渡利 英道; 工藤 正尊; 櫻木 範明; 小田 泰也, 日本産科婦人科学会東北連合地方部会誌, 55, 182, 183, Jun. 2008
  日本産科婦人科学会-東北連合地方部会, Japanese
• カルボプラチンの過敏症発現後にシスプラチンの脱感作療法でプラチナを投与し得た卵巣漿液性腺癌3症例
  保坂 昌芳; 渡利 英道; 森脇 征史; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 蝦名 康彦; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 55, 191, 191, Jun. 2008
  日本産科婦人科学会-東北連合地方部会, Japanese
• 当科におけるGemcitabineを用いた婦人科再発癌の治療経験
  蝦名 康彦; 森脇 征史; 原 洋子; 保坂 昌芳; 荒木 直人; 藤堂 幸治; 武田 真人; 渡利 英道; 工藤 正尊; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 55, 196, 196, Jun. 2008
  日本産科婦人科学会-東北連合地方部会, Japanese
• 当科における婦人科悪性腫瘍に対する鏡視下手術
  工藤 正尊; 保坂 昌芳; 藤堂 幸治; 森脇 征史; 原 洋子; 荒木 直人; 武田 真人; 蝦名 康彦; 渡利 英道; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 55, 198, 198, Jun. 2008
  日本産科婦人科学会-東北連合地方部会, Japanese
• Clusterinを分子標的とした上皮性卵巣癌細胞におけるパクリタキセル感受性増強効果についての検討
  渡利 英道; Mohamed Hassan; 三田村 卓; 保坂 昌芳; 首藤 聡子; 藤堂 幸治; 武田 真人; 蝦名 康彦; 工藤 正尊; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 26, 3, 265, 265, Jun. 2008
  (公社)日本婦人科腫瘍学会, Japanese
• アポトーシス抑制蛋白clusterinと子宮頸癌の術前化学療法反応性ならびに予後との関連
  保坂 昌芳; 渡利 英道; 鹿沼 達哉; 太田 陽子; 三田村 卓; 首藤 聡子; 武田 真人; 蝦名 康彦; 峰岸 敬; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 26, 3, 276, 276, Jun. 2008
  (公社)日本婦人科腫瘍学会, Japanese
• 14歳の子宮体癌症例の診断と治療
  三田村 卓; 保坂 昌芳; 藤堂 幸治; 首藤 聡子; 武田 真人; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 26, 3, 284, 284, Jun. 2008
  (公社)日本婦人科腫瘍学会, Japanese
• Complete hydatidiform mole with coexisting dichorionic diamniotic twins following testicular sperm extraction and intracytoplasmic sperm injection
  山田崇弘; 松田貴雄; 工藤正尊; 山田 俊; 森脇征史; 西 信也; 蝦名康彦; 山田秀人; 加藤秀則; 伊藤智雄; 和氣徳夫; 櫻木範明; 水上尚典, 日本産科婦人科學會雜誌, 60, 3, 999, 999, Mar. 2008
  Japanese
• 神経温存広汎子宮全摘後の膀胱機能の検討
  保坂 昌芳; 藤堂 幸治; 小島 崇史; 三田村 卓; 森脇 征史; 大場 洋子; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 60, 2, 614, 614, Feb. 2008
  (公社)日本産科婦人科学会, Japanese
• 広汎子宮全摘術後の持続的な蓄尿機能低下に影響を及ぼす因子の解析
  三田村 卓; 藤堂 幸治; 小島 崇史; 森脇 征史; 保坂 昌芳; 大場 洋子; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 60, 2, 623, 623, Feb. 2008
  (公社)日本産科婦人科学会, Japanese
• 子宮頸癌におけるリンパ節転移例の予後因子についての検討
  小島 崇史; 保坂 昌芳; 三田村 卓; 森脇 征史; 大場 洋子; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 60, 2, 623, 623, Feb. 2008
  (公社)日本産科婦人科学会, Japanese
• 【快適な術後経過のための工夫と対応】 リンパ節郭清術後のドレナージ
  藤堂 幸治; 森脇 征史; 保坂 昌芳; 原 洋子; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 櫻木 範明, 産科と婦人科, 75, 2, 176, 181, Feb. 2008
  (株)診断と治療社, Japanese
• 子宮脱手術後の腟断端脱に対して行ったlaparoscopic sacral colopexy
  藤堂 幸治; 森脇 征史; 保坂 昌芳; 原 洋子; 荒木 直人; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 52, 1, 35, 35, Jan. 2008
  北海道産科婦人科学会, Japanese
• 小児頭大の筋腫核を経腟的に回収しえた腹腔鏡下筋腫核出術の1例
  保坂 昌芳; 工藤 正尊; 森脇 征史; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 52, 1, 34, 35, Jan. 2008
  北海道産科婦人科学会, Japanese
• 卵巣硬化性間質性腫瘍の一例
  荒木 直人; 武田 真人; 森脇 征史; 原 洋子; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山田 秀人; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 52, 1, 44, 45, Jan. 2008
  北海道産科婦人科学会, Japanese
• 化学療法と卵巣機能不全 (特集 こんなときどうする 産婦人科外来マニュアル) -- (腫瘍)
  蝦名康彦; 櫻木範明, 産科と婦人科, 74, 11, 1491, 1495, Nov. 2007, [Invited]
  診断と治療社, Japanese
• Carboplatinの急性過敏反応発症後にCisplatinを用いた脱感作療法でプラチナを再投与し得た卵巣癌3症例
  保坂 昌芳; 蝦名 康彦; 森脇 征史; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 渡利 英道; 櫻木 範明, 癌と化学療法, 34, 9, 1505, 1508, Sep. 2007
  (株)癌と化学療法社, Japanese
• [Successful desensitization using cisplatin after carboplatin-associated hypersensitivity reactions in 3 cases with recurrent ovarian carcinoma].
  Hosaka M; Ebina Y; Moriwaki M; Hara Y; Araki N; Todo Y; Takeda M; Watari H; Sakuragi N, Gan to kagaku ryoho. Cancer & chemotherapy, 34, 1505, 1508, Sep. 2007, [Peer-reviewed]
  9
• 肺動脈に進展した子宮筋腫術後のintravenous leiomyomatosisの1例
  小田 泰也; 蝦名 康彦; 原 洋子; 保坂 昌芳; 藤堂 幸治; 荒木 直人; 武田 真人; 渡利 英道; 水上 尚典; 櫻木 範明; 日下 剛, 北海道産科婦人科学会会誌, 51, 1, 43, 43, Jun. 2007
  北海道産科婦人科学会, Japanese
• 骨盤外科における機能温存を目指した手術手技の改良 広汎子宮全摘術における効果的自律神経温存法の確立と鏡視下手術導入の検討
  櫻木 範明; 藤堂 幸治; 渡利 英道; 蝦名 康彦; 武田 真人; 保坂 昌芳; 森脇 征史; 原 洋子; 工藤 正尊, 日本外科系連合学会誌, 32, 3, 444, 444, Jun. 2007
  日本外科系連合学会, Japanese
• 婦人科悪性腫瘍における妊孕性温存手術 当科でおこなった浸潤子宮頸癌に対する子宮温存手術(円錐切除と鏡視下リンパ節郭清)
  工藤 正尊; 森脇 征史; 保坂 昌芳; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 水上 尚典; 櫻木 範明, 日本外科系連合学会誌, 32, 3, 515, 515, Jun. 2007
  日本外科系連合学会, Japanese
• 子宮脱手術後の腟断端脱に対して行った腹腔鏡下腟仙骨固定術
  藤堂 幸治; 森脇 征史; 原 洋子; 保坂 昌芳; 荒木 直人; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 産婦人科手術, 18, 203, 203, Jun. 2007
  (株)メジカルビュー社, Japanese
• 系統的骨盤・傍大動脈リンパ節郭清を含む手術療法と術後化学療法による子宮体癌治療後の再発様式
  渡利 英道; 森脇 征史; 保坂 昌芳; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 蝦名 康彦; 工藤 正尊; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 25, 3, 256, 256, Jun. 2007
  (公社)日本婦人科腫瘍学会, Japanese
• 子宮頸部adenosarcomaの1例
  保坂 昌芳; 武田 真人; 小田 泰也; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 51, 1, 38, 39, Jun. 2007
  北海道産科婦人科学会, Japanese
• 骨盤の局所解剖と機能温存手術 膀胱機能温存を目指した系統的自律神経温存広汎子宮全摘術および術後管理について
  藤堂 幸治; 森脇 征史; 保坂 昌芳; 原 洋子; 武田 真人; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 25, 3, 188, 189, Jun. 2007
  (公社)日本婦人科腫瘍学会, Japanese
• 子宮頸部扁平上皮癌small size症例における病理組織学的予後因子と手術法の検討
  武田 真人; 森脇 征史; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 25, 3, 229, 229, Jun. 2007
  (公社)日本婦人科腫瘍学会, Japanese
• 腹腔内に広汎にがんが広がる場合の治療戦略--初回手術時に可能な限りのDebulking surgeryを行うか,Neoadjuvant chemotherapy(NAC)に期待して最小限の手術にとどめるか? (特集 標準手術が実施不能な進行婦人科がんの治療) -- (卵巣がん)
  蝦名康彦; 櫻木範明, 産婦人科の世界, 59, 6, 551, 558, Jun. 2007, [Invited]
  医学の世界社, Japanese
• 広汎子宮全摘術における系統的自律神経温存法と術後膀胱機能の解析
  藤堂 幸治; 保坂 昌芳; 小田 泰也; 原 洋子; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 櫻木 範明, 日本女性骨盤底医学会誌, 4, 1, 143, 149, May 2007
  日本女性骨盤底医学会, Japanese
• 粘膜下筋腫に対する全腹腔鏡下筋腫核出術
  森脇 征史; 工藤 正尊; 加藤 達矢; 保坂 昌芳; 首藤 聡子; 西 信也; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 田中 信一; 大河内 俊洋; 水上 尚典; 櫻木 範明, 日本産科婦人科内視鏡学会雑誌, 22, 2, 309, 309, Mar. 2007
  (一社)日本産科婦人科内視鏡学会, Japanese
• Radical hysterectomy and preservation of physiological functions in cervical cancer
  森脇 征史; 渡利 英道; 蝦名 康彦, 産婦人科治療, 94, 3, 249, 255, Mar. 2007
  永井書店, Japanese
• 子宮頸癌におけるアポトーシス関連蛋白clusterinの発現と予後因子としての有用性に関する臨床病理学的検討
  渡利 英道; 森脇 征史; 保坂 昌芳; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 蝦名 康彦; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 59, 2, 366, 366, Feb. 2007
  (公社)日本産科婦人科学会, Japanese
• リンパ浮腫の複合的理学療法に対する治療効果についての検討
  原 洋子; 小林 範子; 藤野 敬史; 森脇 征史; 保坂 昌芳; 荒木 直人; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 59, 2, 419, 419, Feb. 2007
  (公社)日本産科婦人科学会, Japanese
• 子宮頸癌術後補助治療としての放射線療法と化学療法の検討
  保坂 昌芳; 武田 真人; 森脇 征史; 原 洋子; 荒木 直人; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 59, 2, 575, 575, Feb. 2007
  (公社)日本産科婦人科学会, Japanese
• 子宮頸部扁平上皮癌(3cm未満)の子宮外進展とそれに関連する病理組織学的予後因子の検討
  武田 真人; 荒木 直人; 森脇 征史; 原 洋子; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 59, 2, 581, 581, Feb. 2007
  (公社)日本産科婦人科学会, Japanese
• 腹腔鏡下子宮筋腫核出術における筋腫核の経腟的回収についての検討
  森脇 征史; 工藤 正尊; 加藤 達矢; 保坂 昌芳; 首藤 聡子; 西 信也; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 59, 2, 643, 643, Feb. 2007
  (公社)日本産科婦人科学会, Japanese
• DNAアレイによる子宮頸部擦過細胞診検体および浸潤癌組織検体におけるHPVの検出
  森脇 征史; 渡利 英道; 道又 理恵; 石津 明洋; 小田 泰也; 保坂 昌芳; 藤堂 幸治; 武田 真人; 蝦名 康彦; 櫻木 範明, 日本臨床細胞学会雑誌, 45, Suppl.2, 503, 503, Sep. 2006
  (公社)日本臨床細胞学会, Japanese
• 悪性卵巣腫瘍(境界悪性腫瘍を含む)に対する妊孕能温存治療の臨床的検討
  保坂 昌芳; 山本 律; 岡元 一平; 小田 泰也; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 櫻木 範明, 産婦人科の実際, 55, 8, 1297, 1304, Aug. 2006
  1988〜2001年に妊孕能温存治療を行った悪性卵巣腫瘍50例を対象とし,治療成績,卵巣機能への影響を検討した.初回手術は患側附属器摘出49例,両側腫瘍核出1例であり,片側附属器摘出例中46例に対側卵巣楔状切除,21例に大網切除,17例に後腹膜リンパ節摘出を施行した.33例に術後化学療法を施行し,etoposideを5回以上投与した群では排卵回復までの期間は有意に遅延していた.CAP療法を6コース施行した漿液性腺癌1例では卵巣機能が廃絶した.妊娠を希望した21例中,妊娠は8例に認めた.手術治療のみでも高い治癒率が期待できるIa期,grade 1の上皮性悪性腫瘍や境界悪性腫瘍,抗癌剤感受性の高い悪性胚細胞腫瘍例において,治療が過剰にならないことが妊娠率向上につながると考えられた, 金原出版(株), Japanese
• 子宮体癌III c期の病理組織学的予後因子についての検討
  小田 泰也; 渡利 英道; 藤堂 幸治; 保坂 昌芳; 中郷 賢二郎; 小林 範子; 武田 真人; 蝦名 康彦; 山本 律; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 50, 1, 113, 113, Jun. 2006
  北海道産科婦人科学会, Japanese
• HPV感染と子宮頸癌 メンブレンアレイシステムを用いた子宮頸部細胞診検体および浸潤癌組織検体からのHPV検出
  渡利 英道; 武田 真人; 小田 泰也; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 24, 3, 213, 213, Jun. 2006
  (公社)日本婦人科腫瘍学会, Japanese
• 子宮頸部腺癌における血清腫瘍マーカー値・腫瘍径とリンパ節転移との関連について
  保坂 昌芳; 武田 真人; 中郷 賢二郎; 小田 泰也; 小林 範子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 北海道産科婦人科学会会誌, 50, 1, 106, 107, Jun. 2006
  北海道産科婦人科学会, Japanese
• 子宮頸癌の広汎子宮全摘術後ハイリスク症例に対する補助療法の検討
  保坂 昌芳; 武田 真人; 小田 泰也; 原 洋子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 24, 3, 300, 300, Jun. 2006
  (公社)日本婦人科腫瘍学会, Japanese
• 子宮体癌手術におけるリンパ節郭清の個別化 術前リンパ節転移予測スコア妥当性の研究
  藤堂 幸治; 小田 泰也; 保坂 昌芳; 武田 真人; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 24, 3, 305, 305, Jun. 2006
  (公社)日本婦人科腫瘍学会, Japanese
• A case of myolipoma of the retroperitoneum
  KUBOTA Kanako; TAKEDA Hiroko; ODA Yasunari; EBINA Yasuhiko; OMATU Tokuhiko; ITOH Tomoo, 診断病理 : Japanese journal of diagnostic pathology, 23, 2, 160, 163, 30 Apr. 2006
  Japanese
• DNA array法による子宮頸部細胞診検体および子宮頸部浸潤癌組織検体中のヒトパピローマウイルス(HPV)の検出
  渡利 英道; 小田 泰也; 保坂 昌芳; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 蝦名 康彦; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 58, 2, 374, 374, Feb. 2006
  (公社)日本産科婦人科学会, Japanese
• Weekly paclitaxel/5-fluorouracil併用療法を用いplatinum-free intervalを考慮した再発・抵抗性卵巣漿液性腺癌に対する治療成績
  保坂 昌芳; 渡利 英道; 小田 泰也; 原 洋子; 荒木 直人; 藤堂 幸治; 武田 真人; 蝦名 康彦; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 58, 2, 431, 431, Feb. 2006
  (公社)日本産科婦人科学会, Japanese
• 子宮頸癌に対するRetroperitoneal approachによる鏡視下リンパ節郭清
  工藤 正尊; 保坂 昌芳; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 58, 2, 602, 602, Feb. 2006
  (公社)日本産科婦人科学会, Japanese
• 子宮体癌手術におけるリンパ節郭清術適応の個別化 術前リンパ節転移予測スコア(LNM score)のValidation Study
  藤堂 幸治; 小田 泰也; 保坂 昌芳; 原 洋子; 荒木 直人; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 58, 2, 606, 606, Feb. 2006
  (公社)日本産科婦人科学会, Japanese
• 再発卵巣癌の手術治療計画におけるFDG-PETの有用性と限界について
  小田 泰也; 蝦名 康彦; 原 洋子; 保坂 昌芳; 藤堂 幸治; 荒木 直人; 武田 真人; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 58, 2, 627, 627, Feb. 2006
  (公社)日本産科婦人科学会, Japanese
• 子宮頸部扁平上皮癌における術前検査とNAC
  武田 真人; 小田 泰也; 原 洋子; 保坂 昌芳; 荒木 直人; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 58, 2, 592, 592, Feb. 2006
  (公社)日本産科婦人科学会, Japanese
• P1-175 卵巣癌に対するDJ療法(ドセタキセル・カルボプラチン併用療法)の第I-II相臨床試験(Group 23 卵巣腫瘍XIII,一般演題,講演要旨,第58回日本産科婦人科学会学術講演会)
  蝦名 康彦, 日本産科婦人科學會雜誌, 58, 2, 429, 429, 01 Feb. 2006
  社団法人 日本産科婦人科学会, Japanese
• 婦人科癌再発診断におけるFDG-PETの有用性と限界に関する検討
  蝦名 康彦; 小田 泰也; 保坂 正芳; 原 洋子; 藤堂 幸治; 荒木 直人; 武田 真人; 渡利 英道; 櫻木 範明, 日本婦人科腫瘍学会雑誌 = The journal of the Japan Society of Gynecologic Oncology, 24, 1, 53, 58, 25 Jan. 2006, [Peer-reviewed]
  Japanese
• 卵巣原発扁平上皮癌の1例
  寺島 瑞恵; 藤堂 幸治; 明石 大輔; 見延 進一郎; 小林 範子; 藤本 俊郎; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 北海道産科婦人科学会会誌, 49, 1, 38, 38, Jan. 2006
  北海道産科婦人科学会, Japanese
• 子宮頸部腺癌における血清腫瘍マーカー値・腫瘍径とリンパ節転移との関連について
  保坂 昌芳; 武田 真人; 中郷 賢二郎; 小田 泰也; 小林 範子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 53, 78, 78, Nov. 2005
  日本産科婦人科学会-東北連合地方部会, Japanese
• 子宮体癌III c期の病理組織学的予後因子についての検討
  小田 泰也; 渡利 英道; 藤堂 幸治; 保坂 昌芳; 中郷 賢二郎; 小林 範子; 武田 真人; 蝦名 康彦; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 53, 83, 83, Nov. 2005
  日本産科婦人科学会-東北連合地方部会, Japanese
• 臨床での位置づけ 婦人科領域での有用化 悪性腫瘍診断における展望 婦人科がんの術前評価 (今月の臨床 婦人科の新しい画像診断法--PETを中心として) -- (ポジトロンエミッショントモグラフィ(PET))
  蝦名 康彦; 櫻木 範明, 臨床婦人科産科, 59, 11, 1482, 1487, Nov. 2005, [Invited], [Lead author, Corresponding author]
  医学書院, Japanese
• 子宮体癌におけるCyr61の発現について
  渡利 英道; 熊 桜; 保坂 昌芳; 藤堂 幸治; 武田 真人; 蝦名 康彦; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 23, 3, 354, 354, Jun. 2005
  (公社)日本婦人科腫瘍学会, Japanese
• 広汎子宮全摘術における膀胱機能温存法
  藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 山本 律; 工藤 正尊; 水上 尚典; 櫻木 範明, 産婦人科手術, 16, 138, 138, Jun. 2005
  (株)メジカルビュー社, Japanese
• DNAarray法による子宮頸癌検体中ヒトパピローマウイルスの検出
  保坂 昌芳; 渡利 英道; 藤堂 幸治; 武田 真人; 蝦名 康彦; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 23, 3, 352, 352, Jun. 2005
  (公社)日本婦人科腫瘍学会, Japanese
• 当科で経験した婦人科悪性腫瘍の脳転移症例の検討
  小田 泰也; 武田 真人; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 23, 3, 356, 356, Jun. 2005
  (公社)日本婦人科腫瘍学会, Japanese
• 再発・抵抗性卵巣癌に対するweekly paclitaxel/5-fluorouracil併用療法のfeasibility study
  中郷 賢二郎; 渡利 英道; 小田 泰也; 保坂 昌芳; 藤堂 幸治; 武田 真人; 蝦名 康彦; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 23, 3, 365, 365, Jun. 2005
  (公社)日本婦人科腫瘍学会, Japanese
• 当科における子宮頸部Bulky扁平上皮癌に対する広汎子宮全摘手術療法の治療成績
  武田 真人; 小田 泰也; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 23, 3, 374, 374, Jun. 2005
  (公社)日本婦人科腫瘍学会, Japanese
• 妊娠中に子宮頸部悪性腺腫の合併を疑った症例
  藤堂 幸治; 保坂 昌芳; 武田 真人; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 23, 3, 387, 387, Jun. 2005
  (公社)日本婦人科腫瘍学会, Japanese
• 再発卵巣癌の診断と治療 (特集 増えている卵巣癌の対策)
  蝦名 康彦; 櫻木 範明, 産婦人科治療, 90, 6, 989, 995, Jun. 2005, [Invited], [Lead author]
  永井書店, Japanese
• 当科で経験した子宮体部癌肉腫の3例
  小田 泰也; 武田 真人; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明; 太田 聡; 伊藤 智雄, 日本臨床細胞学会雑誌, 44, Suppl.1, 135, 135, Mar. 2005
  (公社)日本臨床細胞学会, Japanese
• 当科で経験した卵管癌の4例
  石川 聡司; 武田 真人; 小田 泰也; 保坂 昌芳; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明; 太田 聡; 伊藤 智雄, 日本臨床細胞学会雑誌, 44, Suppl.1, 144, 144, Mar. 2005
  (公社)日本臨床細胞学会, Japanese
• 広汎子宮全摘術における新しい系統的自律神経温存法と術後膀胱機能の解析
  藤堂 幸治; 武田 真人; 小林 範子; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 57, 2, 422, 422, Feb. 2005
  (公社)日本産科婦人科学会, Japanese
• p53癌抑制遺伝子のdominant negative変異は進行子宮体癌の予後因子である
  董 培新; 渡利 英道; 蝦名 康彦; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 57, 2, 448, 448, Feb. 2005
  (公社)日本産科婦人科学会, Japanese
• 再発・抵抗性卵巣癌に対するweekly paclitaxel/5-fluorouracil併用療法のfeasibility study
  渡利 英道; 小田 泰也; 根岸 広明; 山村 満恵; 保坂 昌芳; 小林 範子; 藤堂 幸治; 武田 真人; 蝦名 康彦; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 57, 2, 455, 455, Feb. 2005
  (公社)日本産科婦人科学会, Japanese
• 卵巣悪性腫瘍(境界悪性腫瘍を含む)に対する妊孕能温存治療の臨床的検討
  保坂 昌芳; 山本 律; 小田 泰也; 小林 範子; 藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 57, 2, 619, 619, Feb. 2005
  (公社)日本産科婦人科学会, Japanese
• 婦人科癌再発症例の治療方針決定に際してFDG-PETは有用か?
  蝦名 康彦; 小田 泰也; 保坂 昌芳; 小林 範子; 藤堂 幸治; 武田 真人; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 57, 2, 633, 633, Feb. 2005
  (公社)日本産科婦人科学会, Japanese
• 当科におけるBulky子宮頸部扁平上皮癌に対する広汎子宮全摘手術療法の治療成績
  武田 真人; 小田 泰也; 保坂 昌芳; 小林 範子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 57, 2, 423, 423, Feb. 2005
  (公社)日本産科婦人科学会, Japanese
• 北海道大学大学院医学研究科病態制御学専攻生殖・発達医学講座 婦人科学分野 : 新時代の女性医学の発展をめざして
  蝦名 康彦, 北海道醫學雜誌 = Acta medica Hokkaidonensia, 80, 1, 169, 171, 01 Jan. 2005
  Japanese
• [Treatment of ovarian cancer with pelvic and paraaortic lymph node metastasis].
  Ebina Y; Yamamoto R; Sakuragi N, Nihon rinsho. Japanese journal of clinical medicine, 62 Suppl 10, 565, 569, Oct. 2004, [Peer-reviewed]
• 癌治療とクリニカルPET 卵巣癌再発診断におけるFDG-PETの有用性に関する検討
  蝦名 康彦; 中郷 賢二郎; 小田 泰也; 小林 範子; 藤堂 幸治; 武田 真人; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本癌治療学会誌, 39, 2, 401, 401, Sep. 2004
  (一社)日本癌治療学会, Japanese
• 脈管侵襲と傍大動脈リンパ節転移部位数による子宮体癌III c期の予後層別化
  渡利 英道; 藤堂 幸治; 保坂 昌芳; 中郷 賢二郎; 小田 泰也; 小林 範子; 武田 真人; 蝦名 康彦; 山本 律; 水上 尚典; 櫻木 範明, 日本癌治療学会誌, 39, 2, 851, 851, Sep. 2004
  (一社)日本癌治療学会, Japanese
• 当科で経験した子宮頸部乳頭状扁平上皮癌の2例
  保坂 昌芳; 武田 真人; 小田 泰也; 見延 進一郎; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明; 太田 聡; 伊藤 智雄, 日本臨床細胞学会雑誌, 43, Suppl.2, 481, 481, Sep. 2004
  (公社)日本臨床細胞学会, Japanese
• 子宮体部小細胞癌の一例
  藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本臨床細胞学会雑誌, 43, Suppl.2, 497, 497, Sep. 2004
  (公社)日本臨床細胞学会, Japanese
• 系統的自律神経温存広汎子宮全摘術と術前・術後の尿流動態学的検討
  藤堂 幸治; 佐々木 瑞恵; 小林 範子; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 櫻木 範明, 日本外科系連合学会誌, 29, 3, 593, 593, Jun. 2004
  日本外科系連合学会, Japanese
• 小腸原発Gastrointestinal stromal tumor(GIST)の一例
  藤堂 幸治; 武田 真人; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 22, 3, 246, 246, Jun. 2004
  (公社)日本婦人科腫瘍学会, Japanese
• 当科で経験した子宮頸部乳頭状扁平上皮癌の4例
  武田 真人; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 22, 3, 211, 211, Jun. 2004
  (公社)日本婦人科腫瘍学会, Japanese
• 脈管侵襲と傍大動脈リンパ節転移部位数は子宮体癌IIIc期の予後因子である
  渡利 英道; 藤堂 幸治; 武田 真人; 蝦名 康彦; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 22, 3, 227, 227, Jun. 2004
  (公社)日本婦人科腫瘍学会, Japanese
• 卵巣癌再発診断におけるFDG-PETの有用性に関する検討
  蝦名 康彦; 藤堂 幸治; 武田 真人; 渡利 英道; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 22, 3, 233, 233, Jun. 2004
  (公社)日本婦人科腫瘍学会, Japanese
• S3-3 初期卵巣癌(T1/T2)症例における腹腔細胞診とリンパ節転移との関連(シンポジウム3 : (卵巣がんにおける細胞診の現状と問題点)
  蝦名 康彦; 藤堂 幸治; 武田 真人; 渡利 英道; 山本 律; 櫻木 範明, 日本臨床細胞学会雑誌, 43, 1, 22 May 2004
  特定非営利活動法人日本臨床細胞学会, Japanese
• 系統的自律神経温存広汎子宮全摘術と術前・術後の尿流動態学的検討
  藤堂 幸治; 寺島 瑞恵; 小林 範子; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本ウロギネコロジー研究会誌, 1, 1, 37, 37, May 2004
  日本女性骨盤底医学会, Japanese
• 直腸子宮内膜症に発生した類内膜腺癌に子宮体部類内膜腺癌を同時発生した一例
  藤堂 幸治; 寺島 瑞恵; 明石 大輔; 見延 進一郎; 小林 範子; 藤本 俊郎; 武田 真人; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 51, 113, 114, Mar. 2004
  日本産科婦人科学会-東北連合地方部会, Japanese
• 卵巣腫瘍との鑑別が困難であった小腸Gastrointestinal stromal tumor(GIST)の二症例
  寺島 瑞恵; 藤堂 幸治; 小林 範子; 見延 進一郎; 藤本 俊郎; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 51, 119, 119, Mar. 2004
  日本産科婦人科学会-東北連合地方部会, Japanese
• 卵巣癌再発におけるFDG-PETの有用性
  明石 大輔; 蝦名 康彦; 小林 範子; 見延 進一郎; 藤本 俊郎; 藤堂 幸治; 武田 真人; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会東北連合地方部会誌, 51, 122, 122, Mar. 2004
  日本産科婦人科学会-東北連合地方部会, Japanese
• 卵巣癌再発診断におけるFDG-PETの有用性に関する検討
  蝦名 康彦; 明石 大輔; 寺島 瑞恵; 小林 範子; 池田 研; 藤堂 幸治; 武田 真人; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 56, 2, 312, 312, Feb. 2004
  (公社)日本産科婦人科学会, Japanese
• 子宮頸部腺癌における血清腫瘍マーカー値・腫瘍径とリンパ節転移との関連について
  武田 真人; 明石 大輔; 寺島 瑞恵; 小林 範子; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 56, 2, 550, 550, Feb. 2004
  (公社)日本産科婦人科学会, Japanese
• 初期卵巣癌におけるリンパ節転移について
  根岸 広明; 武田 真人; 藤本 俊郎; 見延 進一郎; 小林 範子; 渡利 英道; 蝦名 康彦; 山本 律; 津村 宣彦; 水上 尚典; 櫻木 範明, 日本産科婦人科学会雑誌, 56, 2, 581, 581, Feb. 2004
  (公社)日本産科婦人科学会, Japanese
• 子宮頸部小細胞癌2例の検討
  藤本 俊郎; 見延 進一郎; 武田 真人; 藤堂 幸治; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本臨床細胞学会雑誌, 42, Suppl.2, 417, 417, Sep. 2003
  (公社)日本臨床細胞学会, Japanese
• 子宮頸部に浸潤した急性骨髄性白血病の一例
  武田 真人; 太田 聡; 伊藤 智雄; 見延 進一郎; 藤堂 幸治; 藤本 俊郎; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本臨床細胞学会雑誌, 42, Suppl.2, 421, 421, Sep. 2003
  (公社)日本臨床細胞学会, Japanese
• 卵巣原発扁平上皮癌の一例
  藤堂 幸治; 蝦名 康彦; 寺島 瑞恵; 藤本 俊郎; 武田 真人; 渡利 英道; 櫻木 範明, 日本臨床細胞学会雑誌, 42, Suppl.2, 514, 514, Sep. 2003
  (公社)日本臨床細胞学会, Japanese
• 卵巣腫瘍との鑑別が困難であった小腸原発gastrointestinal stromal tumor(GIST)の一例
  寺島 瑞恵; 藤堂 幸治; 藤本 俊郎; 武田 真人; 蝦名 康彦; 渡利 英道; 櫻木 範明, 日本臨床細胞学会雑誌, 42, Suppl.2, 520, 520, Sep. 2003
  (公社)日本臨床細胞学会, Japanese
• 卵巣悪性腫瘍(境界悪性腫瘍を含む)における妊孕能温存症例の臨床的検討
  山本 律; 見延 進一郎; 小林 範子; 藤本 俊郎; 武田 真人; 蝦名 康彦; 渡利 英道; 工藤 正尊; 岡元 一平; 晴山 仁志; 水上 尚典; 櫻木 範明, 日本癌治療学会誌, 38, 2, 241, 241, Sep. 2003
  (一社)日本癌治療学会, Japanese
• 子宮頸部初期浸潤癌における脈管侵襲及びリンパ節転移の検討
  蝦名 康彦; 岡元 一平; 小林 範子; 藤堂 幸治; 藤本 俊郎; 見延 進一郎; 武田 真人; 渡利 英道; 山本 律; 水上 尚典; 櫻木 範明, 日本癌治療学会誌, 38, 2, 372, 372, Sep. 2003
  (一社)日本癌治療学会, Japanese
• 子宮体癌リンパ節転移陽性例の予後因子
  渡利 英道; 藤堂 幸治; 見延 進一郎; 小林 範子; 藤本 俊郎; 武田 真人; 蝦名 康彦; 工藤 正尊; 山本 律; 水上 尚典; 櫻木 範明, 日本癌治療学会誌, 38, 2, 709, 709, Sep. 2003
  (一社)日本癌治療学会, Japanese
• 子宮体癌と腫瘍マーカー : 診断,モニタリング,予後因子 (特集 腫瘍マーカーの利用マニュアル : 臨床応用のUpdate)
  藤本 俊郎; 蝦名 康彦; 山本 律, 産婦人科の実際, 52, 9, 1289, 1299, Sep. 2003
  金原出版, Japanese
• 腫瘍マーカーは婦人科腫瘍の診断と治療にどのくらい有益か? 子宮頸部扁平上皮癌における血清腫瘍マーカー値・腫瘍径とリンパ節転移との関連についての検討
  武田 真人; 藤本 俊郎; 蝦名 康彦; 渡利 英道; 山本 律; 櫻木 範明, 日本婦人科腫瘍学会雑誌, 21, 3, 169, 169, Jun. 2003
  (公社)日本婦人科腫瘍学会, Japanese
• Thromboprophylaxis with Low Molecular Weight Heparin in Thrombophilia-complicated Pregnancy(Abstracts from the Journal of Obstetrics and Gynaecology Research(Vol.28 No.5))
  蝦名 康彦; 山田 秀人; 平山 恵美; 山本 律; 櫻木 範明; 藤本 征一郎, Acta Obstetrica et Gynaecologica Japonica, 54, 11, 1525, 1525, 01 Nov. 2002
  Japan Society of Obstetrics and Gynecology (JSOG), Japanese
• 子宮頸部細胞診追跡例における転帰とHPV感染との関連についての検討
  蝦名 康彦; 白川 洋三; 日野 順子; 佐々木 隆之; 小葉松 洋子; 清野 邦義; 菊池 浩吉, 日本臨床細胞学会雑誌, 41, 1, 22 Mar. 2002
  特定非営利活動法人日本臨床細胞学会, Japanese
• Anesthesia for electroconvulsive therapy during pregnancy - A case report
  T. Ishikawa; S. Kawahara; T. Saito; H. Otsuka; O. Kemmotsu; E. Hirayama; Y. Ebina; S. Fujimoto; T. Inoue; T. Koyama, Japanese Journal of Anesthesiology, 50, 9, 991, 997, 2001, [Peer-reviewed]
  9, Japanese
• 絨毛膜羊膜炎の成因 : 細菌性腟症・頚管炎との関連 (特集 21世紀の絨毛膜羊膜炎対策)
  蝦名 康彦; 佐川 正; 藤本 征一郎, 産婦人科の実際, 50, 1, 5, 12, Jan. 2001, [Invited], [Lead author]
  金原出版, Japanese
• Thromboprophylaxis with low molecular weight heparin (dalteparin) in thrombophilia-complicated pregnancy
  蝦名 康彦; 山田 秀人; 平山 恵美; 和田 真一郎; 岸田 達朗; 長 和俊; 藤本 征一郎, 日本産婦人科・新生児血液学会誌 = The Japanese journal of obstetrical, gynecological & neonatal hematology, 10, 1, S83, S84, 01 May 2000
  Japanese
• Hypocomplementemia correlates with intrauterine growth retardation in systemic lupus erythematosus
  N Kobayashi; H Yamada; T Kishida; EH Kato; Y Ebina; N Sakuragi; G Kobashi; A Tsutsumi; S Fujimoto, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 42, 3, 153, 159, Sep. 1999
  English
• Congenital Cytomegalovirus Infectuin : Case Report with a Trial of Fetal Therapy
  YAMAZAKI Ayano; YAMADA Hideo; HIRAYAMA KATO Emi; EBINA Yasuhiko; KISHIDA Tatsuro; NEGISHI Hiroaki; SAGAWA Tadashi; FUJIMOTO Seiichiro, Acta Obstetrica et Gynaecologica Japonica, 51, 3, 150, 154, 01 Mar. 1999
  Three cases of congenital Cytomegalovirus (CMV) infection were perinatally managed in Hokkaido University Hospital. In case 1, prenatal CT and MRI revealed dilation of ventlicles and calcification in the peliventriculararea. A male infant weighing 3,020g was born at 39 weeks of gestation (GW). He is 9 years old and has a severe hearing problem. In case 2, by prenatal ultrasound examinations, IUGR, dilation of ventricles, and hepatosplenomegaly were detected. A male infant weighing 1,800g was born at 38 GW, and died at 5 months after birth. Fetal ascites was first detected at 25 GW in case 3. Immunoglobulin (2.5g) was directly infused in to the fetal peritoneal cavity at 28 and 29 GW. At 34 GW, a male infant weighing 2,340g was born by cesarean section due to fetal distress. CMV DNA detected by PCR turned negative in neonatal ascites. He is 1 year old and has noneurological abnormality. Direct fetal infusion of immunoglobulin may be beneficial in treating congenital CMV infection., Japan Society of Obstetrics and Gynecology (JSOG), Japanese
• 281 子宮筋腫に関する細胞遺伝学的研究
  星 信彦; 晴山 仁志; 北澤 克彦; 和田 真一郎; 佐藤 修; 蝦名 康彦; 山田 秀人; 佐川 正; 山本 律; 奥山 和彦; 藤野 敬史; 櫻木 範明; 藤本 征一郎, 日本産科婦人科學會雜誌, 51, 0, "S, 275", 20 Feb. 1999
  社団法人日本産科婦人科学会, Japanese
• P-264 習慣流産に対するガンマグロブリン大量療法の試み
  山田 秀人; 平山 恵美; 岸田 達朗; 蝦名 康彦; 藤本 征一郎, 日本産科婦人科學會雜誌, 51, 0, "S, 491", 20 Feb. 1999
  社団法人日本産科婦人科学会, Japanese
• 子宮体癌と腫瘍マーカー
  蝦名康彦, 産婦人科治療, 79, 661, 670, 1999, [Invited], [Lead author, Corresponding author]
• 7 子宮体癌の腹腔細胞診 : 子宮外進展症例における臨床的意義についての検討
  蝦名 康彦; 櫻木 範明; 小林 範子; 桑原 道弥; 藤野 敬史; 藤本 征一郎, 日本臨床細胞学会雑誌, 37, 1, 22 Mar. 1998
  特定非営利活動法人日本臨床細胞学会, Japanese
• 280 子宮体癌におけるテロメラーゼ活性と進行期および病理組織学的因子との関連について
  蝦名 康彦; 藤野 敬史; 古田 伊津子; 山田 秀人; 山本 律; 櫻木 範明; 藤本 征一郎, 日本産科婦人科學會雜誌, 50, 0, "S, 263", 20 Feb. 1998
  社団法人日本産科婦人科学会, Japanese
• 子宮体癌の腹腔洗浄細胞診所見と予後との関連の多変量解析 : 第38回日本臨床細胞学会総会学術集会 : 術中迅速細胞診 : 最近の進歩
  櫻木 範明; 蝦名 康彦; 晴山 仁志; 藤野 敬史; 山本 律; 及川 衛; 涌井 之雄; 十亀 真志; 八重樫 稔; 桑原 道弥; 牧野 田知; 藤本 征一郎, 日本臨床細胞学会雑誌, 36, 1, Mar. 1997
  特定非営利活動法人日本臨床細胞学会, Japanese
• 402 子宮体部, 卵巣および腟の原発悪性腫瘍由来AFPのレクチン結合性
  山本 律; 蝦名 康彦; 保坂 昌芳; 藤野 敬史; 櫻木 範明; 牧野田 知; 藤本 征一郎, 日本産科婦人科學會雜誌, 49, 0, "S, 306", 20 Feb. 1997
  社団法人日本産科婦人科学会, Japanese
• P-108 末破裂卵管妊娠に対するMTX療法の適応ならびに投与法に関する検討
  蝦名 康彦; 藤野 敬史; 古田 伊都子; 牧野田 知; 藤本 征一郎, 日本産科婦人科學會雜誌, 49, 0, "S, 403", 20 Feb. 1997
  社団法人日本産科婦人科学会, Japanese
• 腫瘍マーカー
  蝦名康彦, 産婦人科の実際, 46, 313, 319, 1997, [Invited], [Lead author, Corresponding author]
• 子宮頸部の小細胞癌の1例 : 第35回日本臨床細胞学会秋季大会 : 子宮頸部V
  蝦名 康彦; 晴山 仁志; 古屋 充子; 八重樫 稔; 渡利 英道; 香城 恒麿; 十亀 真志; 牧野田 知; 藤本 征一郎; 荒川 三紀雄; 藤田 美悧; 井上 和秋, 日本臨床細胞学会雑誌, 35, 2, Sep. 1996
  特定非営利活動法人日本臨床細胞学会, Japanese
• 350 バルトリン腺由来の腺様嚢胞癌の穿刺吸引, 捺印細胞像
  府中 基伸; 石倉 浩; 蝦名 康彦; 市村 英毅; 高橋 麻美; 吉木 敬, 日本臨床細胞学会雑誌, 35, 1, 22 Mar. 1996
  特定非営利活動法人日本臨床細胞学会, Japanese

• 〔主要な業績〕母性看護学① 概論・リプロダクティブヘルスと看護
  中込さと子編, 性・生殖に関する生理
  メディカ出版，大阪, Apr. 2023, [Joint work]
• 〔主要な業績〕不育症
  竹下, 俊行; 藤井, 知行; 山田, 秀人, 先天性アンチトロンビン欠乏症
  メジカルビュー社, Jan. 2021, 9784758319966, x, 237p, Japanese, [Joint work]
• 〔主要な業績〕産婦人科専門医のための必修知識
  日本産科婦人科学会, 転移性腫瘍
  日本産科婦人科学会事務局, Nov. 2020, 9784907890223, 1冊, Japanese, [Joint work]
• 〔主要な業績〕読める生かせる説明できる産科の臨床検査ディクショナリー
  蝦名 康彦, 自己抗体検査、サイトメガロウイルス抗体、ヒトパルボウイルスB19
  メディカ出版, Nov. 2018, [Joint work]
• 〔主要な業績〕実践 臨床生殖免疫学
  蝦名 康彦, 妊娠と感染症 パルボウイルスB19
  中外医学社, May 2018, [Joint work]
• 〔主要な業績〕不妊・不育診療指針
  蝦名 康彦, 不妊治療と妊娠 NIPT
  中外医学社, Nov. 2016, [Joint work]
• 〔主要な業績〕患者さんとご家族のための子宮頸がん・子宮体がん・卵巣がん治療ガイドライン 第２版
  蝦名 康彦, 卵巣がん～プラチナ抵抗性再発～
  金原出版, Feb. 2016, [Contributor]
• 婦人科癌診療Q&A～一つ上を行く診療の実践～
  蝦名 康彦, 子宮頸癌の罹患率、死亡率の推移について教えてください。
  中外医学社, Apr. 2014, [Contributor]
• 腫瘍減量手術に適する再発卵巣癌患者の選択におけるFDG-PETの意義
  蝦名 康彦
  メディカルレビュー社, Mar. 2014, [Single work]
• 産科の臨床検査ディクショナリー
  蝦名 康彦, サイトメガロウイルス抗体，ヒトパルボウイルスB19
  メディカ出版, Jan. 2014, [Contributor]
• 内科 増大号 検査値を読む
  蝦名 康彦, ヒト絨毛性ゴナドトロピン
  2013, [Contributor]
• EBM 婦人科疾患の治療
  蝦名 康彦, 子宮体癌：再発癌に対して推奨される化学療法とは？
  中外医学社, 2013, [Contributor]
• プロメテウス婦人科がん最新医療
  蝦名 康彦, 子宮体がんにおける妊孕性温存と妊娠への影響
  金原出版, 2013, [Contributor]
• The management of antiphospholipid antibodies affected pregnancy
  Kenji Tanimura, Antiphospholipid Syndrome
  InTech-Open Access Publisher, 2012, [Contributor]
• A Smarter Path; Dhiscovery PET/CT
  蝦名 康彦, 腫瘍領域における患者のためのPET/CT活用法
  メテオエイト（東京, 2012, [Contributor]
• 腹式単純子宮全摘術．「子宮筋腫の臨床」平松祐司編集
  メジカルビュー社, 2008
• 進行・再発癌に対する化学療法．「婦人科がん標準化学療法の実際」宇田川康博，八重樫伸生編集
  金原出版, 2008
• PET/CT 画像診断のポイント 婦人科癌
  メディカルレビュー社, 2007
• 婦人科腫瘍におけるPET 検査．「産婦人科・専門医に聞く最新の医療」鈴木光明，吉村泰典編集
  中外医学社, 2007
• 卵巣癌の妊孕能温存手術，「よくわかる卵巣癌のすべて」安田 允編集
  永井書店, 2007
• 第二次腫瘍縮小手術の意義．「先端医療シリーズ39産科婦人科の最新医療」武谷雄二編集主幹
  先端医療技術研究社, 2006
• 18F-fluoro-deoxyglucose positron emission tomography for the detection of recurrent ovarian cancer. 「PET and Molecular Imaging, State of the art and future perspectives. International Congress Series 1264」
  ELSEVIER, 2004
• 卵巣癌と境界悪性腫瘍の最新の治療「卵巣腫瘍病理アトラス」，石倉浩編集
  文光堂, 2004
• 超音波断層法（婦人科）「Newエッセンシャル産科学・婦人科学第３版」，池ノ上克共編
  医師薬出版株式会社, 2004
• The presence of high-risk HPV in cervical dysplastic cells is associated with clinical course: long-term follow-up. 「9th biennial meeting of the international gynecologic cancer society」, ed by Mok JE, Quinn MA, Namkoog SE, Kim YT
  Monduzzi Editore, 2002
• 母子感染 サイトメガロウイルス 「図説産婦人科VIEW 38，母子感染」
  メジカルビュー社, 2000
• 常染色体転座保因者・染色体異常モザイク「周産期遺伝相談」
  医学書院, 2000
• 産婦人科とジェネテイクス 「Modern Reproductivity Medicine 3, 生殖ジェネテイクス〜ART向上のための遺伝子学〜」
  メジカルビュー社, 1999

• 〔主要な業績〕未来を創る性と健康：プレコンセプションケアから始めるライフサイクルとキャリア設計
  蝦名康彦
  北海道大学創基150周年記念事業 DEIキャンペーン連続講演会, 18 Dec. 2024
  [Invited]
• 〔主要な業績〕人生100年時代のリプロダクティブ・ヘルス/ライツとライフプラン
  蝦名康彦
  港区立男女平等参画センター「リーブラ」講演会, 21 Jan. 2023
  [Invited]
• 〔主要な業績〕【教育講演】大学生の子宮頸がん予防に対する意識と健康教育としての対応
  蝦名康彦
  第41回 北海道臨床細胞学会学術集会, 28 Nov. 2021, Invited oral presentation
  [Invited]
• 〔主要な業績〕【CloCMip関連研修】母体の感染（リスクと対応）
  北海道看護協会 助産師職能研修会, 02 Oct. 2021, Public discourse
  [Invited]
• 〔主要な業績〕【教育講演】卵巣がん治療・研究における腹水の可能性
  蝦名康彦
  第59回日本臨床細胞学会秋季大会, 21 Nov. 2020, Japanese, Invited oral presentation
  21 Nov. 2020 - 22 Nov. 2020, [Invited]
• 〔主要な業績〕産婦人科と血栓性素因
  第10回神戸シンポジア, Mar. 2019
  [Invited]
• 産婦人科と血栓性素因
  蝦名 康彦
  第８回神戸産婦人科臨床フォーラム, 07 Jan. 2018, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• 〔主要な業績〕性分化疾患のケアと治療～ライフステージに寄り添いながら～
  蝦名 康彦
  第58回 日本母性衛生学会総会, 07 Oct. 2017, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• 産婦人科と血栓性素因
  蝦名 康彦
  第７回北海道産婦人科周術期合併症研究会, 19 Aug. 2017, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• 病態の理解を深めよう～婦人科がん～
  蝦名 康彦
  兵庫県臨床検査技師会 新春セミナー, 16 Jan. 2017, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• シンポジウム「母子感染対策の最前線2016年」本邦におけるパルボウイルスB19母子感染の実態
  蝦名 康彦
  第52回日本周産期・新生児医学会総会・学術集会, 16 Jul. 2016, Japanese, Nominated symposium
  [Invited], [Domestic Conference]
• ワークショップ「母子感染予防に関する最近の話題」本邦におけるパルボウイルスB19母子感染の実態
  蝦名 康彦
  第26回日本産婦人科・新生児血液学会学術集会, 01 Jun. 2016, Japanese, Nominated symposium
  [Invited], [Domestic Conference]
• 婦人科再発癌手術を考える
  蝦名 康彦
  第４回高知産婦人科周術期セミナー, 26 Feb. 2016, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• 再発卵巣癌化学療法のエビデンスと現状
  蝦名 康彦
  中外婦人科腫瘍セミナー, 20 Feb. 2016, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• 子宮頸部無形成・双角子宮症例に対する形成術～頸部瘢痕組織を利用する工夫～
  蝦名康彦; 村田友香; 田中恵里加; 森田宏紀; 山田秀人
  第38回日本産婦人科手術学会, 28 Nov. 2015, Japanese, Public symposium
  [Domestic Conference]
• 【教育講演】 今さら聞けない、子宮頸部の病理と臨床
  蝦名 康彦
  第133回近畿産科婦人科学会, 25 Oct. 2015, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• Low levels of plasma protein S, protein C and coagulation factor XII during early pregnancy and adverse pregnancy outcome
  Yasuhiko Ebina; Masahiro Ieko; Sumiyoshi Naito; Gen Kobashi; Masashi Deguchi; Hisanori Minakami; Tatsuya Atsumi; Hideto Yamada
  International Society for the Hypertension in Pregnancy (ISSHP) European Congress, 24 Sep. 2015, English, Oral presentation
  [International presentation]
• 【Invited Lecture】 Toward optimized therapy plans using FDG PET/CT for the patients with gynecologic cancers
  YASUHIKO EBINA
  Joint Symposium of University of Liege and Kobe University, 13 May 2015, English, Invited oral presentation
  [Invited], [International presentation]
• 【特別講演】アバスチンの求められるもの ～当科の卵巣癌治療例を通して～
  蝦名 康彦
  第7回神戸シンポジア, 14 Feb. 2015, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• Phenotypic differences of T cells and macrophages in the decidua obtained from spontaneous abortion
  YASUHIKO EBINA
  The 9th Conference of the Pacific Rim Society for Fertility and Sterility, 13 Nov. 2013, English, Poster presentation
  [International presentation]
• A trial of immunoglobulin fetal therapy for symptomatic congenital cytomegalovirus infection
  YASUHIKO EBINA
  17th International Conference on Prenatal Diagnosis and Therapy, 03 Jul. 2013, English, Poster presentation
  [International presentation]
• Diagnostic value of IgG avidity for prediction of congenital cytomegalovirus infection
  YASUHIKO EBINA
  17th International Conference on Prenatal Diagnosis and Therapy, 03 Jul. 2013, English, Poster presentation
  [International presentation]
• 【ランチョンセミナー】 FDG-PET/CTで子宮がん・卵巣がん診療はどう変わったか？
  蝦名 康彦
  第65回日本産科婦人科学会学術講演会, 10 May 2013, Japanese, Public discourse
  [Invited], [Domestic Conference]
• 【ワークショップ】 自然流産における脱落膜T細胞、マクロファージの解析
  蝦名 康彦
  第65回日本産科婦人科学会学術講演会, 10 May 2013, Japanese, Public symposium
  [Domestic Conference]
• 【教育講演】先天性アンチトロンビン欠乏症合併妊娠の診断と治療
  蝦名 康彦
  第２回周産期血液・免疫セミナー神戸, 01 Dec. 2012, Japanese, Public discourse
  [Invited], [Domestic Conference]
• Low IgG Avidity and Ultrasound Fetal Abnormality Predict Congenital Cytomegalovirus Infection
  YASUHIKO EBINA
  Combined Meetings: 4th Congenital Cytomegalovirus Conference and 14th International CMV/BataHerpesvirus Workshop, 29 Oct. 2012, English, Poster presentation
  [International presentation]
• ssessment of treatment in patients with recurrent ovarian cancer using PET-CT：Potential change of disease free interval and chemotherapeutic regimen
  YASUHIKO EBINA
  14ｔｈ Biennial Meeting of the International Gynecologic Cancer Society, 13 Oct. 2012, English, Poster presentation
  [International presentation]
• 【シンポジウム】腫瘍シンポジウム「PETを用いた悪性腫瘍の治療戦略～個別化医療を視野に入れて～」 卵巣癌診療におけるPET-CTによる治療個別化の現状とその問題点について
  蝦名 康彦
  第52回日本核医学会学術総会, 11 Oct. 2012, Japanese, Nominated symposium
  [Domestic Conference]
• 【ワークショップ】「早期卵巣癌を対象とした新規臨床試験」 卵巣癌の臨床試験におけるPET-CTの導入とその問題点
  蝦名 康彦
  第123回 日本産科婦人科学会関東連合学術集会, 17 Jun. 2012, Japanese, Nominated symposium
  [Domestic Conference]
• 「FDG-PET/CTで子宮がん・卵巣がん診療はどう変わったか？」
  蝦名 康彦
  PETサマーセミナー2012 in 松本, 2012, Japanese, Public discourse
  [Invited], [Domestic Conference]
• 特別講演「子宮がん・卵巣がん診療におけるPET-CTのインパクト ～婦人科医は、何を知りたいのか？～」
  蝦名 康彦
  第53回兵庫県核医学研究会, 2011, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• 特別講演「子宮がん・卵巣がん診療におけるPET-CTのインパクト ～婦人科医は、何を知りたいのか？～」
  蝦名 康彦
  第二回東北FDG-PET研究会, 2011, Japanese, Public discourse
  [Invited], [Domestic Conference]
• 特別講演「再発卵巣癌治療 ～どのように選択する？～」
  蝦名 康彦
  徳島卵巣がん化学療法講演会, 2011, Japanese, Public discourse
  [Invited], [Domestic Conference]
• ランチョンセミナー「子宮がん・卵巣がん診療におけるPET-CTのインパクト ～婦人科医は、何を知りたいのか？～」
  蝦名 康彦
  第70回日本医学放射線学会総会, 2011, Japanese, Invited oral presentation
  [Invited], [Domestic Conference]
• ランチョンセミナー「日常臨床でのＰＥＴ/ＣＴの活用について」婦人科癌診療におけるＦＤＧ－ＰＥＴの有用性について
  第10回日本核医学会春季大会（東京）, 2010, Public discourse
  [Invited], [Domestic Conference]
• Impact of FDG-PET on the decision making for ovarian cancer recurrence
  40th Annual Meeting of SGO（米国，サンアントニオ）, 2009, Poster presentation
• 高得点演題「卵巣癌再発に対して，FDG-PETを用いた症例選択により行うsecondary debulking surgeryは，生存期間延長に寄与する」
  第61回日本産科婦人科学会学術集会（京都）, 2009
• シンポジウム“子宮体癌腹腔洗浄細胞診の今日的話題”「子宮体癌の腹腔細胞診にお ける，液状処理と免疫組織化学導入による診断精度向上の試み」
  第50回日本臨床細胞学会総会（東京）, 2009
  [Invited]
• 細胞検査士要望教育シンポジウム“細胞診の将来と可能性～癌治療の選択および予後 推定における細胞診の役割～”「卵巣癌における組織型と治療戦略；細胞診が果たし 得る役割について」
  第50回日本臨床細胞学会総会（東京）, 2009
  [Invited]
• シンポジウム“卵巣癌治療の新たな展開～10年後を見据えて～”「FDG-PETを用いた 症例選択により行う再発卵巣癌腫瘍減量手術は，生存期間延長に寄与する」
  第47回日本癌治療学会総会・学術集会（横浜）, 2009
• シンポジウム“悪性腫瘍の診療に不可欠なPET検査”「PETの臨床応用；婦人科癌 への応用」
  第99回北海道癌談話会（札幌）, 2009
• 特別講演「PET：婦人科癌診療に与えたインパクト」
  蝦名 康彦
  第2回愛知PET臨床利用研究会, 2008, Japanese, Invited oral presentation
  [Invited]
• ランチョンセミナー「PET：婦人科癌診療に与えたインパクト」
  第115回日本産科婦人科学会 関東連合地方部会学術集会（東京）, 2008
• 教育講演「最新治療の理解と看護が行う生活障害支援のベストプラクティス；婦人科がん診療アップデート」
  日総研看護セミナー（札幌）, 2008
  [Invited]
• 教育講演「婦人科疾患の臨床と経腹超音波検査の有用性」
  JSS北海道第９会地方会（帯広）, 2008
• ンポジウム“PETのがん診療への利用”「卵巣がん診療におけるFDG-PETの有用性」
  第５回北海道PET研究会（札幌）, 2007
• ランチョンセミナー「婦人科臨床におけるPET活用のノウハウ〜PET診断のコツとピットフォール〜」
  第59回日本産科婦人科学会（京都）, 2007
• ランチョンセミナー「婦人科がん診療におけるFDG-PETの有用性と今後の展開」
  第４１回日本婦人科腫瘍学会（大阪）, 2006
• ワークショップ“婦人科悪性腫瘍の臨床におけるPETの有効性とその限界”「婦人科癌再発診断におけるFDG-PETの有用性と限界に関する検討」
  第38回婦人科腫瘍学会（和歌山）, 2005
• 高得点演題「卵巣癌再発診断におけるFDG-PETの有用性に関する検討」
  第56回日本産科婦人科学会学術集会（東京）, 2004
• シンポジウム“卵巣がんにおける細胞診の現状と問題点”「初期卵巣癌(T1/T2)症例に おける腹腔細胞診とリンパ節転移との関連」
  第45回日本臨床細胞学会総会（福岡）, 2004
• シンポジウム”腫瘍マーカーを用いた婦人科疾患の管理”「子宮体癌の診断・管理における腫瘍マーカー活用へのアプローチ」
  第５回日本産婦人科腫瘍マーカー・遺伝子診断学会学術集会（東京）, 2001
• シンポジウム”子宮頸癌検診は体癌発見を早めるか？”「北海道における集検での 子宮体癌検診〜第二次老健法後14年間の取り組み〜」
  第10回日本婦人科がん検診学会学術集会（東京）, 2001

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• 母性看護学援助論Ⅰ, 2024年, 学士課程, 医学部
• 人間と文化, 2024年, 学士課程, 全学教育
• 保健生理学, 2024年, 学士課程, 医学部

• THE JAPAN SOCIETY FOR MENOPAUSE AND WOMEN'S HEALTH
• JAPAN SOCIETY OF PERINATAL AND NEONATAL MEDICINE
• Japan society of gynecological cancer screening
• JAPAN SOCIETY OF GYNECOLOGICAL AND OBSTETRICAL SURGERY
• JAPAN SOCIETY OF GYNECOLOGIC ONCOLOGY
• THE JAPANESE SOCIETY OF CLINICAL CYTOLOGY
• Japan Society of Obstetrics and Gynecology
• 日本思春期学会
• 日本看護科学学会
• 日本母性衛生学会

• ライフコース視点による月経前症候群ネットワーク解析と女性健康支援モデルの構築
  科学研究費助成事業
  01 Apr. 2026 - 31 Mar. 2029
  蝦名 康彦
  日本学術振興会, 基盤研究(C), 北海道大学, 26K13666
• ネットワーク分析による産後うつ病の精神病理の解明と個別化した支援の探求
  科学研究費助成事業 基盤研究(C)
  Apr. 2021 - Mar. 2025
  蝦名 康彦
  わが国では，周産期医療および母子保健において，産後うつ病のケアと対応が大きな課題となっている。本研究は，妊産婦の抑うつ不安症状を対象として，新手法であるネットワーク分析を行い，その病態理解の深化へつなげるものである．そして，その知見により現場の支援に関する具体的な提言をすることを目的として計画した．
  しかし，2021年は新型コロナウイルス感染症の影響により，全国の産婦人科臨床現場でケアの中止・縮小といった多大なる影響がでた．そこで，病院の協力が不可欠である臨床データを用いた多数例での検討に入る前に，予備的検討として既存の公的な大型データセット使用の許可を得て，産後女性の抑うつ不安症状に関するネットワーク分析を実施した．これらは産後の横断的なデータであるといえる．それにより，産褥期の女性に特有といえる抑うつ不安症状のネットワーク構造が，はじめて明らかとなった．そして，ネットワークの中で中心性の高い症状や橋渡し症状が特定された．さらに分娩後の時期（１ヶ月，６ヶ月）による相違，サブカテゴリーによる比較について，詳細な解析へ移行している．なお，解析の途中で，予測できなかったデータ取扱いや具体的な処理方法についての問題が発生したが，ひとつひとつ解決法を見出し，この点でも新たに取得するデータ解析にむけて望ましい状況であるといえる．
  一方，臨床の前向きデータとして取得や解析の参考となりうる，コロナ禍の影響を含めた産後うつ病に対するケアの現状について全国調査を2022年5月に行った．その結果はすでに論文にて発表した．産科医療機関におけるコロナ禍の影響は，現在も続いているため，この情報を新データ取得等に活かしていく．
  日本学術振興会, 基盤研究(C), 北海道大学, 21K10818
• HLA class II complex antibody in recurrent pregnancy loss and pregnancy complications
  Grants-in-Aid for Scientific Research
  01 Apr. 2017 - 31 Mar. 2021
  Yamada Hideto
  The aim of this study was to evaluate association between aβ2GPI/HLA-DR7 complex antibody and recurrent pregnancy loss (RPL), infertility, and pregnancy complications. Fifty-two (22.9%) of 227 women with RPL, 24 (19.8%) of 121 women with unexplained RPL, and 22 (19.3%) of 114 women with APS symptoms but not aPL tested positive for the neo-self antibody. 19% of FGR, 14% of HDP, 8% of premature delivery at 34 or less weeks of gestation, 12% of infertility also tested positive for the antibody. The neo-self antibody may be involved in the pathogenesis of RPL, infertility, as well as pregnancy complications.
  Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C), Kobe University, 17K11235
• Participation of and regulatory B cells, dendritic cells, and natural killer cells in recurrent pregnancy loss
  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
  01 Apr. 2017 - 31 Mar. 2020
  Deguchi Masashi
  CD94+ natural killer (NK) cells and CD43+ CD27 high B cells show a tendency to increase in the peripheral blood of women with recurrent pregnancy loss (RPL) compared with women without pregnancy loss. In the deciduae, M1 macrophages increased in miscarriages with normal fetal chromosome compared with miscarriages with abnormal fetal chromosome or induced abortion. M2 macrophages. M2 polarization in deciduae is favorable for the maintenance of early stages of pregnancy. As for CD44 expression of NK cells, CD44 expression in peripheral blood NK cell was not changed in RPL women, but CD44+ uterine NK cells show a tendency to increase in the deciduae of miscarriages with normal fetal chromosome. Cytotoxic CD44+ NK cells in the deciduae might be a more impoprtant factor than that in peripheral blood during nonpregnant period.
  Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C), Kobe University, 17K11234
• PITX1 expression and the telomerase control in an endometrial menstrual cycle and carcinogenic process
  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
  01 Apr. 2013 - 31 Mar. 2017
  Ebina Yasuhiko
  PITX1 protein was expressed in the tumor of the case with poorly-differentiated uterine cancer. However, no expression of PITX1 in more than 90% of the case with uterine cancer. Therefore, this might be associated with telomerase overexpression. PITX1 expression was detected in normal endometrium. Specific relationships could not be obtained regarding to menstrual cycle and carcinogenesis. I keep on analyzing the data that can be got throughout this period.
  Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C), Kobe University, 25462593

• 子宮体がん治療ガイドライン（2023年版）評価委員
  01 Oct. 2022 - Present
  Planning etc, Review
  Academic society etc
• 卵巣がん・卵管癌・腹膜癌治療ガイドライン（2020年版）評価委員
  Jan. 2020 - Jul. 2020
  Planning etc, Review
  Review
• 子宮頸癌治療ガイドライン（2017年版）作成委員（幹事）
  May 2015 - Jul. 2017
  Planning etc, Review
  Review
• 卵巣がん治療ガイドライン（2015年版）作成委員（幹事）
  Jun. 2013 - Mar. 2015
  Planning etc, Review
  Review
• 子宮体がん治療ガイドライン（2013年版）作成委員（幹事）
  Jun. 2011 - Oct. 2013
  Planning etc, Review
  Review
• 子宮頸癌治療ガイドライン（2011年版）作成委員（幹事）
  Aug. 2009 - Aug. 2011
  Planning etc, Review
  Review

• ３世代でつなぐ女性の健康 ～白老町から始まるライフコース健康モデル～
  14 Mar. 2026
  Lecturer
  第4回北大と考える健康講座in白老町「白老町と北大が描く健康づくりの未来〜これまでとこれから〜」

  
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• 更年期から考える 女性のライフコースと健康 ～三世代でつなごう！
  21 Dec. 2025
  Lecturer
  第1回北大と考える健康講座 in白老町「つなごう！考えよう！女性の健康」

  
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• リプロダクティブヘルスを科学する
  03 Nov. 2020 - 03 Nov. 2020
  Lecturer
  北海道大学保健科学研究院
  公開講座2020「ようこそヘルスサイエンスの世界へ」
• 「最新情報でがんにそなえる」子宮がん 最新の診断と治療
  06 May 2017
  Lecturer
  第１５回日本癌治療学会市民公開講座（神戸市）
• 兵庫17事例協働調査委員会委員長
  Jul. 2012 - Dec. 2014
  Investigator
  日本医療安全調査機構モデル事業

• 「健康づくり」協働成果を発表 北大と白老長が講座
  24 Mar. 2023
  苫小牧民報
  [Paper]
• 「早めの対処で子宮頸癌は予防できる！」
  01 Apr. 2018
  阪神電車
  ホッと! HANSHIN
  [Pr]
• 「アステラス製薬 健やかライフ ～子宮筋腫～」
  13 Apr. 2015
  ABCラジオ
  ドッキリハッキリ三代澤康司です
  [Media report]

• Sep. 2023 - Present
  日本思春期学会 性教育認定講師（Aコース、Bコース）
• Oct. 2019 - Present
  J-MELS ベーシックコース・インストラクター
  日本母体救命システム普及協議会(J-CIMELS)
• Mar. 2016 - Present
  日本専門医機構 産婦人科専門医
• Apr. 2008 - Present
  日本がん治療認定医機構 認定医
• Feb. 2007 - Present
  日本婦人科腫瘍学会 婦人科腫瘍専門医
• Dec. 1996 - Present
  日本臨床細胞学会 細胞診専門医