大日方　裕紀 (オオヒナタ　ヒロノリ)

保健科学研究院　保健科学部門　基盤看護学分野助教
Last Updated :2026/04/14

■研究者基本情報

学位

  • 修士（看護学）, 慶應大学, 2020年03月
  • 博士（看護学）, 東北大学, 2023年03月

Researchmap個人ページ

ホームページURL

ORCID ID

J-Global ID

研究分野

  • ライフサイエンス, 臨床看護学, フレイル, 緩和ケア, Phase of Illness

担当教育組織

■経歴

学歴

  • 2020年04月 - 2023年03月, 東北大学, 大学院医学系研究科保健学専攻, 緩和ケア看護学分野
  • 2018年04月 - 2020年03月, 慶應義塾大学, 健康マネジメント研究科, 修士（看護学）, 日本国

■研究活動情報

論文

  • Measuring the Complexity of Palliative Care: A Single-Center Retrospective Study
    Hironori Ohinata, Mitsunori Miyashita, Isseki Maeda
    Journal of Pain and Symptom Management, 2025年10月, ［査読有り］, ［筆頭著者］
    研究論文（学術雑誌）
  • Palliative care needs of patients with chronic limb-threatening ischemia: A scoping review
    Hironori Ohinata, Naomi Akiyama, Arisa Kawashima, Hanako Nozu, Haruka Tamura, Kei Matoba, Miyuki Toda, Shintaro Togashi
    Journal of Pain and Symptom Management, 2025年08月, ［査読有り］, ［筆頭著者］
    研究論文（学術雑誌）
  • 脳卒中リハビリテーション看護認定看護師における脳卒中後疲労の認識に関する実態調査—A Survey on Recognition of Post-Stroke Fatigue Among Certified Nurses in Stroke Rehabilitation Nursing
    柳本 麻衣子, 雲 杉, 大日方 裕紀, 佐藤 善久, 結城 美智子
    日本健康医学会雑誌 = Journal of Japan Health Medicine Association / 日本健康医学会 編, 34, 2, 225, 231, 東京 : 日本健康医学会, 2025年07月, ［査読有り］
    日本語
  • Reliability and validity of the Japanese version of the palliative care phase in palliative care facilities.
    Hironori Ohinata, Masanori Mori, Maho Aoyama, Nao Ito, Tomoko Shigeno, Tomoya Iida, Yuko Matsumura, Hiroaki Tsukuura, Akemi Shirado Naito, Kengo Imai, Naosuke Yokomichi, Tatsuya Morita, Mitsunori Miyashita
    Japanese journal of clinical oncology, 2025年05月08日, ［査読有り］, ［筆頭著者］, ［国際誌］
    英語, 研究論文（学術雑誌）, BACKGROUND: Palliative care phase is a tool to assess five phases that reflect a patient's care needs: stable, unstable, deteriorating, terminal, and bereavement. The palliative care phase is routinely used to describe the clinical status of patients and their families. Australia has established nationwide benchmarks for comparing care services. However, the reliability of palliative care in Japan has not yet been verified. This study aimed to develop a Japanese version of the palliative care phase and examine its inter-rater reliability. METHODS: This was a multicenter, cross-sectional study. Based on previous studies, two healthcare providers evaluated the single-patient phase and calculated kappa coefficients. The reliability was assessed between March 2024 and November 2024 in a palliative care facility in Japan. RESULTS: A total of 419 phase evaluations were conducted. The inter-rater reliability was a kappa of 0.47 (95% confidence interval 0.40-0.54). Assessment disagreements were most common during the unstable and deteriorating phases (11.7%). There were no statistically significant differences in the matches or mismatches in the assessment of the adequacy of the phases (P = 0.338). CONCLUSION: The Japanese version of the palliative care phase was well-adapted for use in clinical palliative care. However, the concepts underlying these phases are not clearly distinguishable. In the future, we need to further educate healthcare providers and accumulate experience through on-the-job training to improve the quality of care through palliative care outcome measurements and benchmarking during the palliative care phase.
  • Association Between Dynapenia and Polypharmacy Among Community-dwelling Older Adults　　　　　　　　　　　　　　　
    Hironori Ohinata, Miku Izutsu, Shan Yun, Naoko Miyajima, Michiko Yuki
    Aging Medicine and Healthcare, 2025年04月, ［査読有り］, ［筆頭著者］
  • COVID-19流行下における地域在住高齢者のQOLの変化に関する文献レビュー
    今野 りょう, 大日方 裕紀, 雲 杉, 結城 美智子
    日本健康医学会雑誌, 33, 4, 550, 558, 日本健康医学会, 2025年01月30日, ［査読有り］
    日本語, Coronavirus Disease 2019（以下 COVID-19）は世界的規模の災害であり，とくに高齢者にとっては生命を脅かす問題である。そのため感染予防策は地域在住高齢者の日常生活に大きな影響を与え，Quality of life（以下 QOL）も変化したと推察される。本研究の目的は文献レビューによりCOVID-19流行下における地域在住高齢者のQOLの変化および影響を及ぼした要因を明らかにすることである。COVID-19，地域在住高齢者，QOLを主なキーワードとして，5つのデータベースで検索をおこなった。適格基準に沿ってスクリーニングを行い，2023年3月までに発表された論文を対象とした。該当論文は28件であった。COVID-19の流行下において地域在住高齢者のQOLは向上，維持，低下していた。QOLに影響を与える要因は，年齢，性別などの対象者の背景に関するものや，感染対策による外出自粛に伴う社会活動の減少であった。とくに行動制限による社会的な孤独感は，精神的健康に影響を及ぼしQOLを低下させる要因であった。今後の研究では，感染予防を行いながらネットワーク技術を用いて社会とのつながりを維持する方法の検討が必要である。
  • Accessibility of Specialized Palliative Care in Hokkaido using Open Data
    Hironori Ohinata, Shintaro Togashi
    Palliative Care Research, 2025年, ［査読有り］, ［筆頭著者］
    研究論文（学術雑誌）
  • Association between Dynapenia and Multimorbidity in Community-Dwelling Older Adults: A Systematic Review
    Hironori Ohinata, Shan Yun, Naoko Miyajima, Michiko Yuki
    Annals of Geriatric Medicine and Research, 2024年09月30日, ［査読有り］, ［筆頭著者］
    研究論文（学術雑誌）
  • Phase of Illness at the time of being referred to the hospital palliative care team and changes after the intervention
    Hironori Ohinata, Hideyuki Hirayama, Maho Aoyama, Eriko Satomi, Yoshiyuki Kizawa, Mayuko Miyazaki, Keita Tagami, Ryuichi Sekine, Kozue Suzuki, Nobuyuki Yotani, Koji Sugano, Hirofumi Abo, Akihiro Sakashita, Kazuki Sato, Sari Nakagawa, Yoko Nakazawa, Jun Hamano, Mitsunori Miyashita
    Progress in Palliative Care, 2024年03月03日, ［査読有り］, ［筆頭著者］
    研究論文（学術雑誌）
  • 看護実習前知識確認試験問題の正答率と識別指数を用いた問題の適切性の検討 Computer Based Testing導入に向けた取り組み　　　　　　　　　　　　　　　
    稲岡 希実子, 大日方 裕紀, 古山 陽一, 武田 彩子, 中川 陽子, 二瓶 映美, 菱谷 純子, 安田 真美, 岡田 佳詠
    国際医療福祉大学学会誌, 29, 1, 146, 155, 国際医療福祉大学学会, 2024年03月, ［査読有り］
    日本語
  • Polypharmacy, potentially inappropriate medication, and dysphagia in older inpatients; A multi-center cohort study.
    Shintaro Togashi, Hironori Ohinata, Taiji Noguchi, Hidetaka Wakabayashi, Mariko Nakamichi, Akio Shimizu, Shinta Nishioka, Ryo Momosaki
    Annals of geriatric medicine and research, 2024年01月17日, ［査読有り］, ［国際誌］
    英語, 研究論文（学術雑誌）, BACKGROUND: Although the relationship between medication status, symptomatology, and outcomes has been evaluated, data on the prevalence of polypharmacy and potentially inappropriate medications (PIMs) and the association of polypharmacy and PIMs with swallowing function during follow-up are limited among hospitalized patients aged ≥65 years with dysphagia. METHODS: In this 19-center cohort study, we registered 467 inpatients aged ≥65 years and evaluated those with the Food Intake LEVEL Scale (FILS) scores ≤8 between November 2019 and March 2021. Polypharmacy was defined as prescribing ≥5 medications and PIMs were identified based on the 2023 Updated Beers criteria®. We applied a generalized linear regression model to examine the association of polypharmacy and PIMs with FILS score at discharge. RESULTS: We analyzed 399 participants (median age, 83.0 years; males, 49.8%). The median follow-up was 51.0 days interquartile range, 22.0-84.0 days]. Polypharmacy and PIMs were present in 67.7% of and 56.1% of patients, respectively. After adjusting for covariates, neither polypharmacy (β = 0.05 [95% confidence interval (CI), -0.04-0.13], p = 0.30) nor non-steroidal anti-inflammatory medications (β = 0.09 [95%CI, -0.02-0.19], p = 0.10) were significantly associated with FILS score at discharge. CONCLUSIONS: The results of this study indicated a high proportion of polypharmacy and PIMs among inpatients aged ≥65 years with dysphagia. Although these prescribed conditions were not significantly associated with swallowing function at discharge, our findings suggest the importance of regularly reviewing medications to ensure the appropriateness of prescriptions when managing older inpatients.
  • 緩和ケアにおけるPhase of Illness(Palliative Care Phase)に関する文献レビュー
    大日方裕紀, 大日方裕紀, 青山真帆, 宮下光令
    日本がん看護学会誌(Web), 37, 2023年, ［査読有り］, ［筆頭著者］
  • Symptoms, performance status and phase of illness in advanced cancer: multicentre cross-sectional study of palliative care unit admissions.
    Hironori Ohinata, Maho Aoyama, Yusuke Hiratsuka, Masanori Mori, Ayako Kikuchi, Hiroaki Tsukuura, Yosuke Matsuda, Kozue Suzuki, Hiroyuki Kohara, Isseki Maeda, Tatsuya Morita, Mitsunori Miyashita
    BMJ supportive & palliative care, 2022年10月27日, ［査読有り］, ［筆頭著者］, ［国際誌］
    英語, 研究論文（学術雑誌）, OBJECTIVES: To clarify the relationship between Phase of Illness at the time of admission to palliative care units and symptoms of patients with advanced cancer. METHODS: This study was a secondary analysis of the East Asian collaborative cross-cultural Study to Elucidate the Dying process. Palliative physicians recorded data, including Phase of Illness, physical function and the Integrated Palliative care Outcome Scale. We used multinomial logistic regression to analyse ORs for factors associated with Phase of Illness. Twenty-three palliative care units in Japan participated from January 2017 to September 2018. RESULTS: In total, 1894 patients were analysed-50.9% were male, mean age was 72.4 (SD±12.3) years, and Phase of Illness at the time of admission to the palliative care unit comprised 177 (8.9%) stable, 579 (29.2%) unstable, 921 (46.4%) deteriorating and 217 (10.9%) terminal phases. Symptoms were most distressing in the terminal phase for all items, followed by deteriorating, unstable and stable (p<0.001). The stable phase had lower association with shortness of breath (OR 0.73, 95% CI 0.57 to 0.94) and felt at peace (OR 0.73, 95% CI 0.56 to 0.90) than the unstable phase. In the deteriorating phase, weakness or lack of energy (OR 1.20, 95% CI 1.02 to 1.40) were higher, while drowsiness (OR 0.82, 95% CI 0.71 to 0.97) and felt at peace (OR 0.81, 95% CI 0.71 to 0.94) were significantly lower. CONCLUSION: Our study is reflective of the situation in palliative care units in Japan. Future studies should consider the differences in patients' medical conditions and routinely investigate patients' Phase of Illness and symptoms. TRIAL REGISTRARION NUMBER: UMIN000025457.
  • Sensitivity and Specificity of Body Mass Index for Sarcopenic Dysphagia Diagnosis among Patients with Dysphagia: A Multi-Center Cross-Sectional Study.
    Shintaro Togashi, Hidetaka Wakabayashi, Hironori Ohinata, Shinta Nishioka, Yoji Kokura, Ryo Momosaki
    Nutrients, 14, 21, 2022年10月26日, ［査読有り］, ［国際誌］
    英語, 研究論文（学術雑誌）, The accuracy of body mass index (BMI) for sarcopenic dysphagia diagnosis, which remains unknown, was evaluated in this study among patients with dysphagia. We conducted a 19-site cross-sectional study. We registered 467 dysphagic patients aged ≥ 20 years. Sarcopenic dysphagia was assessed using a reliable and validated diagnostic algorithm. BMI was assessed using the area under the curve (AUC) in the receiver operating characteristic analysis to determine diagnostic accuracy for sarcopenic dysphagia. The study included 460 patients (median age, 83.0 years (76.0-88.0); men, 49.8%). The median BMI was 19.9 (17.3-22.6) kg/m2. Two hundred eighty-four (61.7%) patients had sarcopenic dysphagia. The AUC for sarcopenic dysphagia was 0.60-0.62 in the overall patients, male, female, and patients aged ≥ 65 years The BMI cut-off value for sarcopenic dysphagia diagnosis was 20.1 kg/m2 in the overall patients (sensitivity, 58.1%; specificity, 60.2%) and patients aged ≥ 65 years (sensitivity, 59.8%; specificity, 61.8%). Conclusion: Although the AUC, sensitivity and specificity of BMI for sarcopenic dysphagia diagnosis was approximately 0.6, BMI < 20.0 kg/m2 might be a predictor for sarcopenic dysphagia. In clinical settings, if patients with dysphagia have a BMI < 20.0 kg/m2, then sarcopenic dysphagia should be suspected as early as possible after admission.
  • Complexity in the context of palliative care: a systematic review.
    Hironori Ohinata, Maho Aoyama, Mitsunori Miyashita
    Annals of palliative medicine, 2022年09月30日, ［査読有り］, ［筆頭著者］, ［国際誌］
    英語, 研究論文（学術雑誌）, BACKGROUND: People receiving palliative care have complex, wide-ranging, and changing needs, not just physical distress, but also psychosocial, practical, and spiritual. Influences on complexity in palliative care are different among healthcare providers and may depend on diverse aspects of the patient's condition, time, and environment. Therefore, this study aimed to integrate and describe the perspective of complexity in palliative care. METHODS: We used an integrative review, which is a method of compiling, summarizing, and analyzing existing insights from previous studies. We conducted an electronic literature search in MEDLINE (Ovid), PsycINFO (EBSCOhost), Web of Science Core Collection, and CINAHL (EBSCOhost), examining literature from May 1972 to September 2020 and updated in December 2020. Subsequently, synthesis without meta-analysis of the findings was completed. RESULTS: We identified 32 peer-reviewed articles published in English. The included literature mainly originated in Europe and the United States. The research methods included quantitative studies (n=13), qualitative studies (n=12), case studies (n=3), and reviews (n=4). We identified 29 that influenced complexity in palliative care, 25 perceptions of the patient, including background and physical, psychological, social, and spiritual; two perceptions in the healthcare setting; and two perceptions in the socio-cultural setting. Above all, the perceptions of complexity in palliative care included younger age, prognosis, and spirituality. In addition, we added the identified perceptions of complexity with references to the complexity model in palliative care. DISCUSSION: Although this review was limited in its search strategy and some data sources may have been overlooked, it still provided perceptions that influenced complexity in palliative care. These complex influencing perceptions are necessary for patients to receive appropriate palliative care at the right time and for health care providers to conduct a multi-disciplinary team approach. Furthermore, longitudinal prospective data are needed to examine the changes and relationships among complexity over time.
  • 抗がん剤変更時における高齢消化器がん患者のフレイルとQOLの関連
    大日方 裕紀, 矢ヶ崎 香, 浜本 康夫, 平田 賢郎, 須河 恭敬, 小松 浩子
    日本看護科学会誌, 42, 254, 262, 公益社団法人 日本看護科学学会, 2022年, ［査読有り］, ［筆頭著者］
    日本語, 目的：抗がん剤変更時における高齢消化器がん患者のフレイルの実態とQOL の関連を明らかにすることである．

    方法：抗がん剤変更時の65歳以上の消化器がん患者を対象に横断的観察研究を行った．フレイル及びQOLの測定は，G8とEQ-5D-5Lを用いた．

    結果：51名が研究参加を同意し，データ収集と分析を行った．フレイルに該当する高齢消化器がん患者は，40名（78.4%）であった．フレイルには，BMI（p < .001），下腿三頭筋周囲径（p = .023）が関連していた．また，フレイル群は非フレイル群に比べQOLが低かった（p = .04）．

    結論：抗がん剤変更時における高齢消化器がんのフレイル患者の特徴とフレイルサイクルへ陥りやすい集団が明らかになった．治療変更時における高齢がん患者に対するフレイルの評価は，QOLを考慮した個別的な支援の重要な要素になり得る．

その他活動・業績

共同研究・競争的資金等の研究課題

  • 緩和ケアの必要性を示す尺度の信頼性の検証とディスカッションマップの開発
    科学研究費助成事業
    2023年04月01日 - 2025年03月31日
    大日方 裕紀
    本研究は、緩和ケアの必要性を評価するための尺度である「Phase of Illness」の信頼性と妥当性を検証し、緩和ケアの経過を俯瞰するディスカッションマップを作成することを目標としている。この尺度は、緩和ケアの適切な時期の判断や、緩和ケアの介入のアウトカムとして有効であるかどうかを明らかにすることも可能であると考えられている。
    初年度にあたる2023年度は、Phase of Illnessに関する文献レビューを実施し、海外でのPhase of Illnessの研究状況や活用の方法を集約し、日本における実用性を評価した。その結果、「Phase of Illness」はがん患者だけでなく非がん患者にも適用可能であり、医療提供体制や職種を問わず、医療者が容易に評価できることが明らかになった。さらに、「Phase of Illness」は、患者の病状の変化に応じて柔軟に対応できるため、緩和ケアの質を向上させるための有効なツールであると考えられた。これらのことから、Phase of Illnessの評価一致性による信頼性と症状評価による概念妥当性を検証するため、新たな調査項目をエキスパートパネルで検討を行った。対象施設は、緩和ケア病棟および在宅緩和ケア施設を含む複数の医療機関で、データ収集と分析を進めている。この調査により、Phase of Illnessが実際の臨床現場でどのように活用されているか、また、その活用が緩和ケアの質にどのような影響を与えているかを評価することができる。
    日本学術振興会, 若手研究, 北海道大学, 23K16443

主な担当授業

  • 看護研究Ⅱ, 2024年, 学士課程, 医学部
  • 老年看護学実習Ⅰ, 2024年, 学士課程, 医学部
  • 老年看護学援助論, 2024年, 学士課程, 医学部
  • リハビリテーション看護, 2024年, 学士課程, 医学部
  • 保健・医療概論, 2024年, 学士課程, 医学部
  • 看護研究Ⅲ, 2024年, 学士課程, 医学部
  • 看護研究Ⅳ, 2024年, 学士課程, 医学部