May 2022, 日本レオロジー学会, 2021年度日本レオロジー学会奨励賞　　　　　　　　　　　　　　　

Aug. 2021, 北海道大学, 全学教育科目に係る授業アンケートにおけるエクセレント・ティーチャーズ　　　　　　　　　　　　　　　

Apr. 2021, 文部科学省, 令和3年度科学技術分野の文部科学大臣表彰 若手科学者賞　　　　　　　　　　　　　　　

Feb. 2021, 北海道大学, 令和２年度教育研究総長表彰　　　　　　　　　　　　　　　

Sep. 2020, Hokkaido University, Excellent teacher award　　　　　　　　　　　　　　　
中島祐

May 2019, 高分子学会, 広報委員会パブリシティ賞　　　　　　　　　　　　　　　
中島 祐

Jan. 2019, RSC, Soft Matter Presentation Award　　　　　　　　　　　　　　　
Tasuku Nakajima

Jan. 2017, Hokkaido University, Hokkaido University President's Award of Research　　　　　　　　　　　　　　　
Tasuku Nakajima

May 2016, Society of Polymer Science, Japan, Award for Encouragement of Research in Polymer Science　　　　　　　　　　　　　　　
Tasuku Nakajima

Mar. 2015, Hokkaido University, Hokkaido University President's Award of Research　　　　　　　　　　　　　　　
Tasuku Nakajima

Mar. 2015, Hokkaido University, Hokkaido University President's Award of Education　　　　　　　　　　　　　　　
Tasuku Nakajima

Aug. 2014, Hokkaido University, Excellent teacher award　　　　　　　　　　　　　　　
Tasuku Nakajima

Oct. 2013, 日本ゴム協会, 第25回エラストマー討論会 優秀発表賞　　　　　　　　　　　　　　　
中島 祐

Oct. 2012, Soft Matter, Poster Prize at the 9th International Gel Symposium　　　　　　　　　　　　　　　
中島 祐

May 2012, 日本化学会, 優秀講演賞（産業）　　　　　　　　　　　　　　　
中島 祐

Osmosis‐Induced Mechanical Disintegration of Polymer Network Gels
Shou Ohmura, Kosei Oikawa, Takuya Nishimura, Ryuji Kiyama, Jian Ping Gong, Tasuku Nakajima
Small, Jul. 2025
Scientific journal

Yielding of Double-Network Hydrogels with Systematically Controlled Tetra-PEG First Networks
Takahiro Matsuda, Naohiro Kashimura, Takamasa Sakai, Tasuku Nakajima, Takuto Matsushita, Jian Ping Gong
Macromolecules, 24 Jun. 2025
Scientific journal

Effect of the Second Network on First Network Rupture and the Origin of Energy Dissipation in Double Network Hydrogels
Zhi Jian Wang, Gumi Wei, Tasuku Nakajima, Jian Ping Gong
Macromolecules, 13 May 2025
Scientific journal

Mechanochemistry-Induced Universal Hydrogel Surface Modification for Orientation and Enhanced Differentiation of Skeletal Muscle Myoblasts
Yuheng Nie, Qifeng Mu, Yanpeng Sun, Zannatul Ferdous, Lei Wang, Cewen Chen, Tasuku Nakajima, Jian Ping Gong, Shinya Tanaka, Masumi Tsuda
ACS Applied Bio Materials, 21 Apr. 2025
Scientific journal

Hydrogels with prestressed tensegrity structures
Bin Xue, Xu Han, Haoqi Zhu, Qingtai Li, Yu Zhang, Ming Bai, Ying Li, Yiran Li, Meng Qin, Tasuku Nakajima, Wei Wang, Jian Ping Gong, Yi Cao
Nature Communications, 16 Apr. 2025
Scientific journal

Rapid self-strengthening in double-network hydrogels triggered by bond scission
Zhi Jian Wang, Wei Li, Xueyu Li, Tasuku Nakajima, Michael Rubinstein, Jian Ping Gong
Nature Materials, Apr. 2025, [Peer-reviewed]
Scientific journal

Double-network hydrogels with a gradient hydrophobic coating that prevents water evaporation and allows strong adhesion to a solid substrate
Shota Sakurai, Takayuki Kurokawa, Hidemitsu Furukawa, Jian Ping Gong, Tasuku Nakajima
Polymer Journal, Springer Science and Business Media LLC, 08 Jan. 2025, [Peer-reviewed], [Invited], [Last author, Corresponding author]
Scientific journal

Tensile Behaviors of Double Network Hydrogels with Varied First Network Topological and Chemical Structures
Feixue Lu, Tasuku Nakajima, Yong Zheng, Hailong Fan, Jian Ping Gong
Macromolecules, 57, 24, 11520, 11533, American Chemical Society (ACS), 07 Dec. 2024, [Peer-reviewed]
Scientific journal

Gigantic multilayered vesicle-like hydrogel-bilayer composites
Naoto Horihata, Jian Ping Gong, Tasuku Nakajima
Chemistry Letters, 53, 11, Oxford University Press (OUP), 01 Nov. 2024, [Peer-reviewed], [Last author, Corresponding author]
Scientific journal, Abstract

Preparation of large vesicles with high stability is generally difficult. Here, we report the millimeter-scale multilayered vesicle-like hydrogel-bilayer composites with long-term stability through stabilization of the vesicular structure by polymerization of the lipid molecules and gelation of the inner solution. The well-oriented multilayered structure was examined by various methods. Reflecting the multilayered structure, the resulting vesicle-like composites exhibited extremely slow drug release behavior.

Unique stick–slip crack dynamics of double-network hydrogels under pure-shear loading
Yong Zheng, Yiru Wang, Fucheng Tian, Tasuku Nakajima, Chung-Yuen Hui, Jian Ping Gong
Proceedings of the National Academy of Sciences, 121, 30, Proceedings of the National Academy of Sciences, 17 Jul. 2024, [Peer-reviewed]
Scientific journal, In this work, we have found that a prenotched double-network (DN) hydrogel, when subjected to tensile loading in a pure-shear geometry, exhibits intriguing stick–slip crack dynamics. These dynamics synchronize with the oscillation of the damage (yielding) zone at the crack tip. Through manipulation of the loading rate and the predamage level of the brittle network in DN gels, we have clarified that this phenomenon stems from the significant amount of energy dissipation required to form the damage zone at the crack tip, as well as a kinetic contrast between the rapid crack extension through the yielding zone (slip process) and the slow formation of a new yielding zone controlled by the external loading rate (stick process).

Hydrogel morphogenesis induced by force-controlled growth
Zhi Jian Wang, Ji Lin, Tasuku Nakajima, Jian Ping Gong
Proceedings of the National Academy of Sciences, 121, 27, Proceedings of the National Academy of Sciences, 26 Jun. 2024, [Peer-reviewed], [Corresponding author]
Scientific journal, Morphogenesis is one of the most marvelous natural phenomena. The morphological characteristics of biological organs develop through growth, which is often triggered by mechanical force. In this study, we propose a bioinspired strategy for hydrogel morphogenesis through force-controlled chemical reaction and growth under isothermal conditions. We adopted a double network (DN) hydrogel with sacrificial bonds. Applying mechanical force to the gel caused deformation and sacrificial bond rupture. By supplying monomers to the gel, the radicals generated by the bond rupture triggered the formation of a new network inside the deformed gel. This new network conferred plasticity to the elastic gel, allowing it to maintain its deformed shape, along with increased volume and strength. We demonstrated that sheet-shaped DN hydrogels rapidly adopted various three-dimensional shapes at ambient temperature when subjected to forces such as drawing and blowing. This mechanism enables morphogenesis of elastic hydrogels and will promote the application of these materials in biomedical fields and soft machines.

Effect of the Activation Force of Mechanophore on Its Activation Selectivity and Efficiency in Polymer Networks
Zhi Jian Wang, Shu Wang, Julong Jiang, Yixin Hu, Tasuku Nakajima, Satoshi Maeda, Stephen L. Craig, Jian Ping Gong
Journal of the American Chemical Society, 146, 19, 13336, 13346, American Chemical Society (ACS), 02 May 2024, [Peer-reviewed]
Scientific journal

Effect of Predamage on the Fracture Energy of Double-Network Hydrogels
Yong Zheng, Yiru Wang, Tasuku Nakajima, Jian Ping Gong
ACS Macro Letters, 130, 137, American Chemical Society (ACS), 11 Jan. 2024, [Peer-reviewed]
Scientific journal

Role of hierarchy structure on the mechanical adaptation of self-healing hydrogels under cyclic stretching
Xueyu Li, Kunpeng Cui, Yong Zheng, Ya Nan Ye, Chengtao Yu, Wenqi Yang, Tasuku Nakajima, Jian Ping Gong
Science Advances, 9, 51, American Association for the Advancement of Science (AAAS), 22 Dec. 2023, [Peer-reviewed]
Scientific journal, Soft materials with mechanical adaptability have substantial potential for various applications in tissue engineering. Gaining a deep understanding of the structural evolution and adaptation dynamics of soft materials subjected to cyclic stretching gives insight into developing mechanically adaptive materials. Here, we investigate the effect of hierarchy structure on the mechanical adaptation of self-healing hydrogels under cyclic stretching training. A polyampholyte hydrogel, composed of hierarchical structures including ionic bonds, transient and permanent polymer networks, and bicontinuous hard/soft-phase networks, is adopted as a model. Conditions for effective training, mild overtraining, and fatal overtraining are demonstrated in soft materials. We further reveal that mesoscale hard/soft-phase networks dominate the long-term memory effect of training and play a crucial role in the asymmetric dynamics of compliance changes and the symmetric dynamics of hydrogel shape evolution. Our findings provide insights into the design of hierarchical structures for adaptive soft materials.

Azobenzene as a photoswitchable mechanophore
Yiran Li, Bin Xue, Jiahui Yang, Julong Jiang, Jing Liu, Yanyan Zhou, Junsheng Zhang, Mengjiao Wu, Yuan Yuan, Zhenshu Zhu, Zhi Jian Wang, Yulan Chen, Yu Harabuchi, Tasuku Nakajima, Wei Wang, Satoshi Maeda, Jian Ping Gong, Yi Cao
Nature Chemistry, 16, 3, 446, 455, Springer Science and Business Media LLC, 05 Dec. 2023, [Peer-reviewed]
Scientific journal

Thermoresponsive Lamellar Hydrogels with Tunable Turbidity, Structural Color, and Anisotropic Swelling
Yang Han, Yunzhou Guo, Tasuku Nakajima, Jian Ping Gong
ACS Applied Materials & Interfaces, 29 Nov. 2023, [Peer-reviewed], [Corresponding author]
Scientific journal

Swelling Effect on the Yielding, Elasticity, and Fracture of Double-Network Hydrogels with an Inhomogeneous First Network
Yong Zheng, Tasuku Nakajima, Wei Cui, Chung-Yuen Hui, Jian Ping Gong
Macromolecules, 56, 11, 3962, 3972, American Chemical Society (ACS), 17 May 2023, [Peer-reviewed]
Scientific journal

Inverse mechanical-swelling coupling of a highly deformed double-network gel
Chika Imaoka, Tasuku Nakajima, Tsutomu Indei, Masaya Iwata, Wei Hong, Alba Marcellan, Jian Ping Gong
Science Advances, 9, 19, American Association for the Advancement of Science (AAAS), 10 May 2023, [Peer-reviewed], [Corresponding author]
Scientific journal, Mechanical behaviors of a polymer gel are coupled with its swelling behavior. It has been known that typical hydrogels display extension-induced swelling and drying-induced stiffening, called normal mechanical-swelling coupling. In this study, we experimentally found that highly extended double-network (DN) hydrogels exhibit abnormal inverse mechanical-swelling coupling such as extension-induced deswelling and drying-induced softening. We established theoretical hyperelastic and swelling models that reproduced all the complicated mechanical and swelling trends of the highly deformed DN hydrogels. From these theoretical analyses, it is considered that the inverse mechanical-swelling coupling of a DN gel is derived from the extreme nonlinear elasticity of its first network at its ultimate deformation state. These findings contribute toward the understanding of the mechanics of rubber-like materials up to their ultimate deformation and fracture limit.

Mechanical Model for Super-Anisotropic Swelling of the Multi-Cylindrical PDGI/PAAm Gels
Tasuku Nakajima, Kei Mito, Jian Ping Gong
Polymers, 15, 7, 1624, 1624, MDPI AG, 24 Mar. 2023, [Peer-reviewed]
English, Scientific journal, MC-PDGI/PAAm gels are cylindrical composite gels containing poly(dodecyl glyceryl itaconate) (PDGI) as a polymerized lipid oriented in a multilayer tubular shape within a polyacrylamide (PAAm) network. The most unique feature of the MC-PDGI/PAAm gel is its super-anisotropic swelling, wherein the diameter of the gel increases, but the length decreases with an increase in the volume of the gel. Through swelling and small-angle X-ray diffraction experiments, we investigated the effects of PDGI lipid bilayers and polymer network on the swelling of the MC-PDGI/PAAm gel, which suggests that the swelling anisotropy of the MC-PDGI/PAAm gel is dominated by the elasticity of the PDGI bilayers. Furthermore, we investigated the equation of state of the gel that roughly reproduced the experimental swelling results. These findings are crucial for realizing the controlled super-anisotropic swelling of MC-PDGI/PAAm gels and their applications as anisotropic actuation devices.

In Situ and Real-Time Visualization of Mechanochemical Damage in Double-Network Hydrogels by Prefluorescent Probe via Oxygen-Relayed Radical Trapping
Yong Zheng, Julong Jiang, Mingoo Jin, Daiyo Miura, Fei Xue Lu, Koji Kubota, Tasuku Nakajima, Satoshi Maeda, Hajime Ito, Jian Ping Gong
Journal of the American Chemical Society, 145, 13, 7376, 7389, American Chemical Society (ACS), 23 Mar. 2023, [Peer-reviewed]
Scientific journal

Squid/synthetic polymer double-network gel: elaborated anisotropy and outstanding fracture toughness characteristics
Shou Ohmura, Tasuku Nakajima, Masahiro Yoshida, Jian Ping Gong
NPG Asia Materials, 15, 1, Springer Science and Business Media LLC, 20 Jan. 2023, [Peer-reviewed], [Corresponding author]
Scientific journal, Abstract

The hierarchical anisotropy of a biotissue plays an essential role in its elaborate functions. To mimic the anisotropy-based functions of biotissues, soft and wet synthetic hydrogels with sophisticated biotissue-like anisotropy have been extensively explored. However, most existing synthetically manufactured anisotropic hydrogels exhibit fundamental anisotropy and poor mechanical toughness characteristics. In this paper, natural/synthetic hybrid double-network (DN) hydrogels with hierarchical anisotropy and high toughness characteristics are reported. These DN gels are prepared directly by using a squid mantle as an anisotropic soft bioproduct for the primary network and polyacrylamide (PAAm) as a synthetic polymer for the secondary network. The obtained squid/PAAm DN gel maintains the complex orientation of the muscle fibers of the squid mantle and exhibits anisotropic, enhanced mechanical properties and excellent fracture resistance due to its unique composite structure. This hybrid strategy provides a general method for preparing hydrogels with elaborated anisotropy and determining functions derived from the anisotropy.

Sustainable mechanochemical growth of double-network hydrogels supported by vascular-like perfusion
Gumi Wei, Yumeko Kudo, Takahiro Matsuda, Zhi Jian Wang, Qi Feng Mu, Daniel R. King, Tasuku Nakajima, Jian Ping Gong
Materials Horizons, Royal Society of Chemistry (RSC), 2023, [Peer-reviewed], [Corresponding author]
Scientific journal, Double-network (DN) gels are unique mechanochemical materials owing to their structures that can be dynamically remodelled during use.

Effect of Salt on Dynamic Mechanical Behaviors of Polyampholyte Hydrogels
Xueyu Li, Feng Luo, Tao Lin Sun, Kunpeng Cui, Reina Watanabe, Tasuku Nakajima, Jian Ping Gong
Macromolecules, 56, 2, 535, 544, American Chemical Society (ACS), 16 Dec. 2022, [Peer-reviewed]
Scientific journal

Computational Exploration of Polymer Mechanochemistry: Quantitation of Activation Force and Systematic Discovery of Reaction Sites Utilizing Two Forces
Julong Jiang, Koji Kubota, Mingoo Jin, Zhi Jian Wang, Tasuku Nakajima, Hajime Ito, Jian Ping Gong, Satoshi Maeda
American Chemical Society (ACS), 23 Nov. 2022
A series of mechanophores were studied computationally by employing the AFIR (Artificial Force Induced Reaction) method, which applies an artificial force on the molecule to trigger reactions, and meanwhile with a tensile force to simulate a mechanochemical reaction. The calculation results were both qualitatively and quantitatively consistent to those reported experimentally, indicating that the AFIR is a reliable approach to studying mechanochemical reactions. It was then applied to the study of retro-Diels-Alder reactions for the theoretical predictions of activation force levels which are currently unavailable. Moreover, it also helped to reveal the favored geometry for the enhancement of force effect. Later, the AFIR method was employed to study the mechanodegradation of generic polymers. The substituents effect and the polymer tacticity in strengthening the mechanical responsiveness, were highlighted by our study. Given the importance of cross-linker molecules in the double-network (DN) hydrogels, a fully automatic search of mechanochemical transformation pathways of a commonly used cross-linker molecule, N,N'-methylenebisacrylamide (MBAA), was also performed by the AFIR method. Through the work described in this article, we demonstrated that, in the field of polymer mechanochemistry, the AFIR method utilizing two forces is a simple but effective tool to give accurate predictions of activation force levels at any given timescale. In the meantime, the mechanistic study of mechanochemical reactions shown in this article is believed to provide insightful suggestions for the further design and application of mechanophores.

Nanoscale TEM Imaging of Hydrogel Network Architecture
Ryuji Kiyama, Masahiro Yoshida, Takayuki Nonoyama, Tomáš Sedlačík, Hiroshi Jinnai, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong
Advanced Materials, 35, 1, 2208902, 2208902, Wiley, 18 Nov. 2022, [Peer-reviewed]
Scientific journal

Force-triggered rapid microstructure growth on hydrogel surface for on-demand functions
Qifeng Mu, Kunpeng Cui, Wang Zhi jian, Takahiro Matsuda, Wei Cui, Hinako Kato, Shotaro Namiki, Tomoko Yamazaki, Martin Frauenlob, Takayuki Nonoyama, Masumi Tsuda, Shinya Tanaka, Tasuku Nakajima, Jian Ping Gong
Nature Communications, 13, 1, Springer Science and Business Media {LLC}, 20 Oct. 2022, [Peer-reviewed], [Corresponding author]
English, Scientific journal, AbstractLiving organisms share the ability to grow various microstructures on their surface to achieve functions. Here we present a force stamp method to grow microstructures on the surface of hydrogels based on a force-triggered polymerisation mechanism of double-network hydrogels. This method allows fast spatial modulation of the morphology and chemistry of the hydrogel surface within seconds for on-demand functions. We demonstrate the oriented growth of cells and directional transportation of water droplets on the engineered hydrogel surfaces. This force-triggered method to chemically engineer the hydrogel surfaces provides a new tool in addition to the conventional methods using light or heat, and will promote the wide application of hydrogels in various fields.

Rate-Independent Self-Healing Double Network Hydrogels Using a Thixotropic Sacrificial Network
Tomoki Yasui, Yong Zheng, Tasuku Nakajima, Eiji Kamio, Hideto Matsuyama, Jian Ping Gong
Macromolecules, 55, 21, 9547, 9557, American Chemical Society (ACS), 18 Oct. 2022, [Peer-reviewed]
Scientific journal

Azo-Crosslinked Double-Network Hydrogels Enabling Highly Efficient Mechanoradical Generation
Zhi Jian Wang, Julong Jiang, Qifeng Mu, Satoshi Maeda, Tasuku Nakajima, Jian Ping Gong
Journal of the American Chemical Society, American Chemical Society (ACS), 11 Feb. 2022, [Peer-reviewed], [Corresponding author]
Scientific journal

Unique crack propagation of double network hydrogels under high stretch
Ye Zhang, Kazuki Fukao, Takahiro Matsuda, Tasuku Nakajima, Katsuhiko Tsunoda, Takayuki Kurokawa, Jian Ping Gong
Extreme Mechanics Letters, 51, 101588, 101588, Elsevier BV, Feb. 2022, [Peer-reviewed]
Scientific journal

Surfactant induced bilayer-micelle transition for emergence of functions in anisotropic hydrogel
Md Anamul Haque, Takayuki Kurokawa, Tasuku Nakajima, Gen Kamita, Zannatul Fatema, Jian Ping Gong
Journal of Materials Chemistry B, 10, 41, 8386, 8397, Royal Society of Chemistry (RSC), 2022, [Peer-reviewed]
Scientific journal, The polymer-surfactant-assembled lamellar bilayer structure in the hydrogel matrix is tuned by simple molecular triggering to achieve variable macroscopic functionalities of soft photonic hydrogel.

Synthesis of degradable double network gels using a hydrolysable cross-linker
Takanori Yokoi, Akinori Kuzuya, Tasuku Nakajima, Takayuki Kurokawa, Jian Ping Gong, Yuichi Ohya
Polymer Chemistry, 13, 25, 3756, 3762, Royal Society of Chemistry (RSC), 2022, [Peer-reviewed]
Scientific journal, Biodegradable double network (DN) gels with remarkably high mechanical strength and toughness were synthesised. The biodegradable DN gels can be potentially applied in biomedical applications such as cartilage regeneration.

Facile preparation of cellulose hydrogel with Achilles tendon-like super strength through aligning hierarchical fibrous structure
Yun Zhou Guo, Tasuku Nakajima, Md. Tariful Islam Mredha, Hong Lei Guo, Kunpeng Cui, Yong Zheng, Wei Cui, Takayuki Kurokawa, Jian Ping Gong
Chemical Engineering Journal, 428, 132040, 132040, Elsevier {BV}, Jan. 2022, [Peer-reviewed], [Corresponding author], ［Internationally co-authored］, [International Magazine]
English, Scientific journal

How chain dynamics affects crack initiation in double-network gels
Yong Zheng, Takahiro Matsuda, Tasuku Nakajima, Wei Cui, Ye Zhang, Chung-Yuen Hui, Takayuki Kurokawa, Jian Ping Gong
Proceedings of the National Academy of Sciences, 118, 49, 07 Dec. 2021, [Peer-reviewed], [Corresponding author], ［Internationally co-authored］, [International Magazine]
Scientific journal

Revisiting the Origins of the Fracture Energy of Tough Double-Network Hydrogels with Quantitative Mechanochemical Characterization of the Damage Zone
Takahiro Matsuda, Runa Kawakami, Tasuku Nakajima, Yukiko Hane, Jian Ping Gong
Macromolecules, 54, 22, 10331, 10339, American Chemical Society ({ACS}), 23 Nov. 2021, [Peer-reviewed], [International Magazine]
Scientific journal

Nanophase Separation in Immiscible Double Network Elastomers Induces Synergetic Strengthening, Toughening, and Fatigue Resistance
Yong Zheng, Ryuji Kiyama, Takahiro Matsuda, Kunpeng Cui, Xueyu Li, Wei Cui, Yunzhou Guo, Tasuku Nakajima, Takayuki Kurokawa, Jian Ping Gong
Chemistry of Materials, 33, 9, 3321, 3334, American Chemical Society ({ACS}), 11 May 2021, [Peer-reviewed], [Corresponding author], [International Magazine]
Scientific journal

Molecular mechanism of abnormally large nonsoftening deformation in a tough hydrogel
Ya Nan Ye, Kunpeng Cui, Wei Hong, Xueyu Li, Chengtao Yu, Dominique Hourdet, Tasuku Nakajima, Takayuki Kurokawa, Jian Ping Gong
Proceedings of the National Academy of Sciences, 118, 14, e2014694118, e2014694118, Proceedings of the National Academy of Sciences, 06 Apr. 2021, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
English, Scientific journal, Tough soft materials usually show strain softening and inelastic deformation. Here, we study the molecular mechanism of abnormally large nonsoftening, quasi-linear but inelastic deformation in tough hydrogels made of hyperconnective physical network and linear polymers as molecular glues to the network. The interplay of hyperconnectivity of network and effective load transfer by molecular glues prevents stress concentration, which is revealed by an affine deformation of the network to the bulk deformation up to sample failure. The suppression of local stress concentration and strain amplification plays a key role in avoiding necking or strain softening and endows the gels with a unique large nonsoftening, quasi-linear but inelastic deformation.

Experimental Verification of the Balance between Elastic Pressure and Ionic Osmotic Pressure of Highly Swollen Charged Gels
Tasuku Nakajima, Ken-ichi Hoshino, Honglei Guo, Takayuki Kurokawa, Jian Ping Gong
Gels, 7, 2, 39, 39, MDPI AG, 01 Apr. 2021, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
Scientific journal, The equilibrium swelling degree of a highly swollen charged gel has been thought to be determined by the balance between its elastic pressure and ionic osmotic pressure. However, the full experimental verification of this balance has not previously been conducted. In this study, we verified the balance between the elastic pressure and ionic osmotic pressure of charged gels using purely experimental methods. We used tetra-PEG gels created using the molecular stent method (St-tetra-PEG gels) as the highly swollen charged gels to precisely and separately control their network structure and charge density. The elastic pressure of the gels was measured through the indentation test, whereas the ionic osmotic pressure was determined by electric potential measurement without any strong assumptions or fittings. We confirmed that the two experimentally determined pressures of the St-tetra-PEG gels were well balanced at their swelling equilibrium, suggesting the validity of the aforementioned relationship. Furthermore, from single-strand level analysis, we investigated the structural requirements of the highly swollen charged gels in which the elasticity and ionic osmosis are balanced at their swelling equilibrium.

Correction to Preparation of Tough Double- and Triple-Network Supermacroporous Hydrogels through Repeated Cryogelation
Tomáš Sedlačík, Takayuki Nonoyama, Honglei Guo, Ryuji Kiyama, Tasuku Nakajima, Yoshihiro Takeda, Takayuki Kurokawa, Jian Ping Gong
Chemistry of Materials, 32, 24, 10737, 10737, American Chemical Society ({ACS}), 22 Dec. 2020
Scientific journal

Polyzwitterions as a Versatile Building Block of Tough Hydrogels: From Polyelectrolyte Complex Gels to Double-Network Gels
Haiyan Yin, Daniel R. King, Tao Lin Sun, Yoshiyuki Saruwatari, Tasuku Nakajima, Takayuki Kurokawa, Jian Ping Gong
ACS Applied Materials & Interfaces, American Chemical Society ({ACS}), 04 Nov. 2020, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
Scientific journal

Crack Tip Field of a Double-Network Gel: Visualization of Covalent Bond Scission through Mechanoradical Polymerization
Takahiro Matsuda, Runa Kawakami, Tasuku Nakajima, Jian Ping Gong
Macromolecules, American Chemical Society ({ACS}), 27 Oct. 2020, [Peer-reviewed], [International Magazine]
Scientific journal

Preparation of Tough Double- and Triple-Network Supermacroporous Hydrogels through Repeated Cryogelation
Tomáš Sedlačík, Takayuki Nonoyama, Honglei Guo, Ryuji Kiyama, Tasuku Nakajima, Yoshihiro Takeda, Takayuki Kurokawa, Jian Ping Gong
Chemistry of Materials, 32, 19, 8576, 8586, American Chemical Society ({ACS}), 13 Oct. 2020, [Peer-reviewed], [International Magazine]
Scientific journal

Chitin-Based Double-Network Hydrogel as Potential Superficial Soft-Tissue-Repairing Materials
Junchao Huang, Martin Frauenlob, Yuki Shibata, Lei Wang, Tasuku Nakajima, Takayuki Nonoyama, Masumi Tsuda, Shinya Tanaka, Takayuki Kurokawa, Jian Ping Gong
Biomacromolecules, American Chemical Society ({ACS}), 12 Oct. 2020, [Peer-reviewed], [International Magazine]
Scientific journal

Effect of the constituent networks of double-network gels on their mechanical properties and energy dissipation process
Tasuku Nakajima, Takayuki Kurokawa, Hidemitsu Furukawa, Jian Ping Gong
Soft Matter, 16, 37, 8618, 8627, Royal Society of Chemistry (RSC), Oct. 2020, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
English, Scientific journal,

The relationship between composition and mechanical properties of tough double-network hydrogels was clarified by systematic experiments and theoretical investigations.

Lamellar Bilayer to Fibril Structure Transformation of Tough Photonic Hydrogel under Elongation
M. Anamul Haque, Kunpeng Cui, Muhammad Ilyas, Takayuki Kurokawa, Alba Marcellan, Annie Brulet, Riku Takahashi, Tasuku Nakajima, J. Ping Gong
Macromolecules, American Chemical Society (ACS), 12 Jun. 2020, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
English, Scientific journal

Effect of Relative Strength of Two Networks on the Internal Fracture Process of Double Network Hydrogels As Revealed by in Situ Small-Angle X-ray Scattering
Kazuki Fukao, Tasuku Nakajima, Takayuki Nonoyama, Takayuki Kurokawa, Takahiko Kawai, Jian Ping Gong
Macromolecules, American Chemical Society ({ACS}), 25 Feb. 2020, [Peer-reviewed], [International Magazine]
Scientific journal

Effect of void structure on the toughness of double network hydrogels
Tasuku Nakajima, Hidemitsu Furukawa, Yoshimi Tanaka, Takayuki Kurokawa, Jian Ping Gong
Soft Matter, 16, 37, 8618, 8627, Wiley, 2020
Scientific journal

Double-network gels as polyelectrolyte gels with salt-insensitive swelling properties
Tasuku Nakajima, Takaharu Chida, Kei Mito, Takayuki Kurokawa, Jian Ping Gong
Soft Matter, 16, 23, 5487, 5496, Royal Society of Chemistry ({RSC}), 2020, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
English, Scientific journal, Polyelectrolyte gels exhibit intrinsic salt-sensitive swelling behaviour, which causes size instability in ionic environments. Thus, polyelectrolyte gels that show salt-insensitive swelling have been anticipated for applications in ionic environments, such as medical materials used in vivo. We found that double-network (DN) gels consisting of both a polyelectrolyte network and a non-ionic network are resistant to salt-sensitive swelling. This resistance is attributed to their lower osmotic pressure originating from mobile ions relative to the osmotic pressure of mixing at swelling equilibrium. Our investigation indicated that the two contrasting network structures within the DN gels are vital for achieving these properties, where the structures include a highly prestretched and sparse polyelectrolyte network and a coiled and dense non-ionic network. The salt-insensitivity of the DN gels will lead to their unique applications in ionic environments.

Relaxation Dynamics and Underlying Mechanism of a Thermally Reversible Gel from Symmetric Triblock Copolymer
Ya Nan Ye, Kunpeng Cui, Tsutomu Indei, Tasuku Nakajima, Dominique Hourdet, Takayuki Kurokawa, Jian Ping Gong
Macromolecules, American Chemical Society ({ACS}), 26 Nov. 2019, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
Scientific journal

Tough Double-Network Gels and Elastomers from the Nonprestretched First Network
Tasuku Nakajima, Yuhei Ozaki, Ryo Namba, Kumi Ota, Yuki Maida, Takahiro Matsuda, Takayuki Kurokawa, Jian Ping Gong
ACS Macro Letters, 8, 11, 1407, 1412, American Chemical Society ({ACS}), 19 Nov. 2019, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
Scientific journal

Effect of Structure Heterogeneity on Mechanical Performance of Physical Polyampholytes Hydrogels
Kunpeng Cui, Ya Nan Ye, Tao Lin Sun, Liang Chen, Xueyu Li, Takayuki Kurokawa, Tasuku Nakajima, Takayuki Nonoyama, Jian Ping Gong
Macromolecules, 52, 19, 7369, 7378, Oct. 2019, [Peer-reviewed], [International Magazine]
English, Scientific journal

Internal Damage Evolution in Double-Network Hydrogels Studied by Microelectrode Technique
Honglei Guo, Wei Hong, Takayuki Kurokawa, Takahiro Matsuda, Zi Liang Wu, Tasuku Nakajima, Masakazu Takahata, Taolin Sun, Ping Rao, Jian Ping Gong
Macromoledules, 52, 18, 7114, 7122, Sep. 2019, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
English, Scientific journal

Tough double network elastomers reinforced by the amorphous cellulose network
Joji Murai, Tasuku Nakajima, Takahiro Matsuda, Katsuhiko Tsunoda, Takayuki Nonoyama, Takayuki Kurokawa, Jian Ping Gong
Polymer, 178, 121686, 121686, Elsevier {BV}, Sep. 2019, [Peer-reviewed], [Corresponding author]
Scientific journal

鍛えて成長するゲル―破壊による創造の材料科学―　　　　　　　　　　　　　　　
Takahiro Matsuda, Tasuku Nakajima, Jian Ping Gong
現代化学, 581, 53, 57, Aug. 2019, [Invited]
Japanese, Scientific journal

Tough Triblock Copolymer Hydrogels with Different Micromorphologies for Medical and Sensory Materials
Hui Jie Zhang, Feng Luo, Yanan Ye, Tao Lin Sun, Takayuki Nonoyama, Takayuki Kurokawa, Tasuku Nakajima
ACS Applied Polymer Materials, 1, 8, 1948, 1953, Aug. 2019, [Peer-reviewed], [Last author, Corresponding author], ［Internationally co-authored］, [International Magazine]
English, Scientific journal

Fabrication of Tough and Stretchable Hybrid Double-Network Elastomers Using Ionic Dissociation of Polyelectrolyte in Nonaqueous Media
Takahiro Matsuda, Tasuku Nakajima, Jian Ping Gong
Chemistry of Materials, 31, 10, 3766, 3776, American Chemical Society ({ACS}), 28 May 2019, [Peer-reviewed], [International Magazine]
Scientific journal

Hydrophobic Hydrogels with Fruit‐Like Structure and Functions
Guo Hui, Nakajima Tasuku, Hourdet Dominique, Marcellan Alba, Creton Costantino, Hong Wei, Kurokawa Takayuki, Gong Jian Ping
Advanced Materials, 31, 25, e1900702, May 2019, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
English, Scientific journal

Mechanoresponsive self-growing hydrogels inspired by muscle training
Takahiro Matsuda, Runa Kawakami, Ryo Namba, Tasuku Nakajima, Jian Ping Gong
Science, 363, 6426, 504, 508, American Association for the Advancement of Science ({AAAS}), 01 Feb. 2019, [Peer-reviewed], [Corresponding author], [International Magazine]
Scientific journal

Damage cross-effect and anisotropy in tough double network hydrogels revealed by biaxial stretching
Thanh-Tam Mai, Takahiro Matsuda, Tasuku Nakajima, Jian Ping Gong, Kenji Urayama
Soft Matter, Royal Society of Chemistry ({RSC}), 2019, [Peer-reviewed], [International Magazine]
Scientific journal

Network elasticity of a model hydrogel as a function of swelling ratio: from shrinking to extreme swelling states
Ken-ichi Hoshino, Tasuku Nakajima, Takahiro Matsuda, Takamasa Sakai, Jian Ping Gong
SOFT MATTER, 14, 47, 9693, 9701, Dec. 2018, [Peer-reviewed], [Corresponding author], [International Magazine]
English, Scientific journal

刺激応答性発色ゲル
堀端修人, 中島 祐, 龔 剣萍
応用物理学会・有機分子・バイオエレクトロニクス分科会 会誌, 29, 4, 232, 235, Nov. 2018, [Invited]
Japanese

Elastic–Plastic Transformation of Polyelectrolyte Complex Hydrogels from Chitosan and Sodium Hyaluronate
Ran Shi, Tao Lin Sun, Feng Luo, Tasuku Nakajima, Takayuki Kurokawa, Yue Zhen Bin, Michael Rubinstein, Jian Ping Gong
Macromolecules, 51, 21, 8887, 8898, American Chemical Society ({ACS}), Nov. 2018, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
English, Scientific journal, Hydrogels formed by polyelectrolyte complexation (PEC) of oppositely charged biopolymers, free of any chemical additives, are promising biomaterials. In this work, the mechanical behavior of hydrogels consisting of positively charged chitosan and negatively charged sodium hyaluronate (HA) at balanced charge composition is investigated. These hydrogels exhibit strong tensile strain and strain rate dependence. They are elastic-like, independent of the strain rate at small strain, but exhibit plastic-like behavior above the yield point by showing a monotonous decrease of the stress. The cyclic tensile test demonstrates that these hydrogels exhibit small and quickly recoverable hysteresis in the elastic-like region, but large and partially recoverable hysteresis above the yield point. The stress relaxation experiment shows a plateau in the reduced stress followed by an abrupt fracture, and the time-to-failure decreases exponentially with increasing applied step-strain. Such elastic-to-plastic-like transformation of the biopolymer PEC gels is quite different from the behaviors of PEC hydrogels formed by oppositely charged vinyl-type synthetic polyelectrolytes due to the difference in flexibility, charge density, and ionic bond strength of these polymers.

Tough Particle-Based Double Network Hydrogels for Functional Solid Surface Coatings
Riku Takahashi, Kouichi Shimano, Haruka Okazaki, Takayuki Kurokawa, Tasuku Nakajima, Takayuki Nonoyama, Daniel R. King, Jian Ping Gong
Advanced Materials Interfaces, 1801018, 1801018, Wiley, 04 Oct. 2018, [Peer-reviewed], [International Magazine]
Scientific journal

Micro patterning of hydroxyapatite by soft lithography on hydrogels for selective osteoconduction
Ryuji Kiyama, Takayuki Nonoyama, Susumu Wada, Shingo Semba, Nobuto Kitamura, Tasuku Nakajima, Takayuki Kurokawa, Kazunori Yasuda, Shinya Tanaka, Jian Ping Gong
Acta Biomaterialia, 81, 60, 69, Elsevier {BV}, Oct. 2018, [Peer-reviewed], [International Magazine]
English, Scientific journal, Mechanically robust hydrogels are promising biomaterials as artificial supportive tissue. These applications require selective and robust bonding of the hydrogels to living tissue. Recently, we achieved strong in vivo bone bonding of a tough double network (DN) hydrogel, a potential material for use as artificial cartilage and tendon, by hybridizing osteoconductive hydroxyapatite (HAp) in the gel surface layer. In this work, we report micro patterning of HAp at the surface of the DN hydrogel for selective osteoconduction. Utilizing the dissolution of HAp in an acidic environment, the soft lithography technique using an acid gel stamp was adopted to form a high-resolution HAp pattern on the gel. The HAp-patterned gel showed well-regulated migration and adhesion of cells in vitro. Moreover, the HAp-patterned gel showed selective and robust bonding to the rabbit bone tissue in vivo. This HAp soft lithography technique allows for simple and quick preparation of tailor-made osteoconductive hydrogels and can be applied to other hydrogels for selective bone bonding. STATEMENT OF SIGNIFICANCE: Hydrogels, preserving large amount of water, have been studied for next-generation artificial soft tissues. However, fixation of hydrogels to living tissue was unsolved issue for clinical application. Recently, we achieved robust bonding of a tough double network gel to bone in vivo by coating of osteoconductive hydroxyapatite in the gel surface layer. For further progress for practical use, we report the micro patterning of HAp at the surface of the DN hydrogel by using soft lithography technique, to perform selective bonding to only objective area without unnecessary coalescence. The HAp lithography technique is simple, quick and non-toxic method to prepare tailor-made osteoconductive hydrogels and has universality of species of hydrogels.

Distinctive Characteristics of Internal Fracture in Tough Double Network Hydrogels Revealed by Various Modes of Stretching
Thanh-Tam Mai, Takahiro Matsuda, Tasuku Nakajima, Jian Ping Gong, Kenji Urayama
Macromolecules, 51, 14, 5245, 5257, American Chemical Society ({ACS}), 24 Jul. 2018, [Peer-reviewed], [International Magazine]
Scientific journal

Tough and Self-Recoverable Thin Hydrogel Membranes for Biological Applications
Ya Nan Ye, Martin Frauenlob, Lei Wang, Masumi Tsuda, Tao Lin Sun, Kunpeng Cui, Riku Takahashi, Hui Jie Zhang, Tasuku Nakajima, Takayuki Nonoyama, Takayuki Kurokawa, Shinya Tanaka, Jian Ping Gong
Advanced Functional Materials, 28, 31, 1801489, Jun. 2018, [Peer-reviewed], [International Magazine]
English, Scientific journal

A Facile Method to Fabricate Anisotropic Hydrogels with Perfectly Aligned Hierarchical Fibrous Structures
Md. Tariful Islam Mredha, Yun Zhou Guo, Takayuki Nonoyama, Tasuku Nakajima, Takayuki Kurokawa, Jian Ping Gong
Advanced Materials, 30, 9, 1704937, Wiley-VCH Verlag, 01 Mar. 2018, [Peer-reviewed], [International Magazine]
English, Scientific journal

Tough and variable-band-gap photonic hydrogel displaying programmable angle-dependent colors
Md. Anamul Haque, Kei Mito, Takayuki Kurokawa, Tasuku Nakajima, Takayuki Nonoyama, Muhammad Ilyas, Jian Ping Gong
ACS Omega, 3, 1, 55, 62, American Chemical Society, 2018, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
English, Scientific journal

Anisotropic Growth of Hydroxyapatite in Stretched Double Network Hydrogel
Kazuki Fukao, Takayuki Nonoyama, Ryuji Kiyama, Kazuya Furusawa, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong
ACS Nano, 11, 12, 12103, 12110, American Chemical Society, 26 Dec. 2017, [Peer-reviewed]
English, Scientific journal

ダブルネットワークゲル（ DN ゲル）の軟骨応用に向けた検討
野々山貴行, 中島祐, 黒川孝幸, 北村信人, 安田和則, 龔剣萍
FC Report, 35, 4, 148, 152, Oct. 2017
Japanese

Water-Triggered Ductile-Brittle Transition of Anisotropic Lamellar Hydrogels and Effect of Confinement on Polymer Dynamics
Muhammad Ilyas, Md. Anamul Haque, Youfeng Yue, Takayuki Kurokawa, Tasuku Nakajima, Takayuki Nonoyama, Jian Ping Gong
MACROMOLECULES, 50, 20, 8169, 8177, Oct. 2017, [Peer-reviewed]
English, Scientific journal

Supramolecular hydrogels with multi-cylindrical lamellar bilayers: Swelling-induced contraction and anisotropic molecular diffusion
Kei Mito, Md. Anamul Haque, Tasuku Nakajima, Maki Uchiumi, Takayuki Kurokawa, Takayuki Nonoyama, Jian Ping Gong
POLYMER, 128, 373, 378, Oct. 2017, [Peer-reviewed], [Corresponding author]
English, Scientific journal

Anisotropic tough double network hydrogel from fish collagen and its spontaneous in vivo bonding to bone
Md. Tariful Islam Mredha, Nobuto Kitamura, Takayuki Nonoyama, Susumu Wada, Keiko Goto, Xi Zhang, Tasuku Nakajima, Takayuki Kurokawa, Yasuaki Takagi, Kazunori Yasuda, Jian Ping Gong
BIOMATERIALS, 132, 85, 95, Jul. 2017, [Peer-reviewed]
English, Scientific journal

Tough polyion-complex hydrogels from soft to stiff controlled by monomer structure
Feng Luo, Tao Lin Sun, Tasuku Nakajima, Takayuki Kurokawa, Xufeng Li, Honglei Guo, Yiwan Huang, Huijie Zhang, Jian Ping Gong
POLYMER, 116, 487, 497, May 2017, [Peer-reviewed]
English, Scientific journal

Bulk Energy Dissipation Mechanism for the Fracture of Tough and Self-Healing Hydrogels
Tao Lin Sun, Feng Luo, Wei Hong, Kunpeng Cui, Yiwan Huang, Hui Jie Zhang, Daniel R. King, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong
MACROMOLECULES, 50, 7, 2923, 2931, Apr. 2017, [Peer-reviewed]
English, Scientific journal

Energy-Dissipative Matrices Enable Synergistic Toughening in Fiber Reinforced Soft Composites
Yiwan Huang, Daniel R. King, Tao Lin Sun, Takayuki Nonoyama, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong
ADVANCED FUNCTIONAL MATERIALS, 27, 9, Mar. 2017, [Peer-reviewed]
English, Scientific journal

Generalization of the sacrificial bond principle for gel and elastomer toughening
Nakajima, Tasuku
Polymer Journal, 49, 6, 2017
Scientific journal

Stimuli-Responsive Transformation of a Gradient Gel
Tasuku Nakajima, Kenta Hiwatashi, Jian Hu, Takayuki Kurokawa, Jian Ping Gong
KOBUNSHI RONBUNSHU, 74, 4, 311, 318, 2017, [Peer-reviewed], [Lead author, Corresponding author]
Japanese

Double Networkゲルをマトリックスとした骨組織類似構造の創製　　　　　　　　　　　　　　　
深尾 一城, 野々山 貴行, 黒川 孝幸, 中島 祐, きょう 剣萍
日本バイオマテリアル学会大会予稿集, シンポジウム2016, 237, 237, 日本バイオマテリアル学会, Nov. 2016
Japanese

刺激応答性構造色と異方的物性を示すリオトロピック液晶ゲル
中島祐, 龔剣萍
液晶, 20, 4, 212, 217, Oct. 2016, [Peer-reviewed], [Invited]
Japanese

Double-Network Hydrogels Strongly Bondable to Bones by Spontaneous Osteogenesis Penetration
Takayuki Nonoyama, Susumu Wada, Ryuji Kiyama, Nobuto Kitamura, Md. Tariful Islam Mredha, Xi Zhang, Takayuki Kurokawa, Tasuku Nakajima, Yasuaki Takagi, Kazunori Yasuda, Jian Ping Gong
ADVANCED MATERIALS, 28, 31, 6740, +, Aug. 2016, [Peer-reviewed]
English, Scientific journal

Creep Behavior and Delayed Fracture of Tough Polyampholyte Hydrogels by Tensile Test
Sadia Nazneen Karobi, Tao Lin Sun, Takayuki Kurokawa, Feng Luo, Tasuku Nakajima, Takayuki Nonoyama, Jian Ping Gong
MACROMOLECULES, 49, 15, 5630, 5636, Aug. 2016, [Peer-reviewed]
English, Scientific journal

Molecular Structure and Properties of Click Hydrogels with Controlled Dangling End Defect
Ao-kai Zhang, Jun Ling, Kewen Li, Guo-dong Fu, Tasuku Nakajima, Takayuki Nonoyama, Takayuki Kurokawa, Jian Ping Gong
JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 54, 13, 1227, 1236, Jul. 2016, [Peer-reviewed]
English, Scientific journal

Tough Physical Double-Network Hydrogels Based on Amphiphilic Triblock Copolymers
Hui Jie Zhang, Tao Lin Sun, Ao Kai Zhang, Yumihiko Ikura, Tasuku Nakajima, Takayuki Nonoyama, Takayuki Kurokawa, Osamu Ito, Hiroyuki Ishitobi, Jian Ping Gong
ADVANCED MATERIALS, 28, 24, 4884, 4890, Jun. 2016, [Peer-reviewed]
English, Scientific journal

Self-Healing Behaviors of Tough Polyampholyte Hydrogels
Abu Bin Ihsan, Tao Lin Sun, Takayuki Kurokawa, Sadia Nazneen Karobi, Tasuku Nakajima, Takayuki Nonoyama, Chanchal Kumar Roy, Feng Luo, Jian Ping Gong
MACROMOLECULES, 49, 11, 4245, 4252, Jun. 2016, [Peer-reviewed]
English, Scientific journal

Strong and Tough Polyion-Complex Hydrogels from Oppositely Charged Polyelectrolytes: A Comparative Study with Polyampholyte Hydrogels
Feng Luo, Tao Lin Sun, Tasuku Nakajima, Daniel R. King, Takayuki Kurokawa, Yu Zhao, Abu Bin Ihsan, Xufeng Li, Honglei Guo, Jian Ping Gong
MACROMOLECULES, 49, 7, 2750, 2760, Apr. 2016, [Peer-reviewed]
English, Scientific journal

Quantitative Observation of Electric Potential Distribution of Brittle Polyelectrolyte Hydrogels Using Microelectrode Technique
Honglei Guo, Takayuki Kurokawa, Masakazu Takahata, Wei Hong, Yoshinori Katsuyama, Feng Luo, Jamil Ahmed, Tasuku Nakajima, Takayuki Nonoyama, Jian Ping Gong
MACROMOLECULES, 49, 8, 3100, 3108, Apr. 2016, [Peer-reviewed]
English, Scientific journal

Yielding Criteria of Double Network Hydrogels
Takahiro Matsuda, Tasuku Nakajima, Yuki Fukuda, Wei Hong, Takamasa Sakai, Takayuki Kurokawa, Ung-il Chung, Jian Ping Gong
MACROMOLECULES, 49, 5, 1865, 1872, Mar. 2016, [Peer-reviewed], [Corresponding author]
English, Scientific journal

Structure Transition and Function Modification of a Hydrogel Based on Lamellar Bilayers
Kei Mito, Tasuku Nakajima, Takayuki Nonoyama, Jian Ping Gong
KOBUNSHI RONBUNSHU, 73, 2, 157, 165, 2016, [Peer-reviewed], [Invited]
Japanese

Stretching-induced ion complexation in physical polyampholyte hydrogels
Kunpeng Cui, Tao Lin Sun, Takayuki Kurokawa, Tasuku Nakajima, Takayuki Nonoyama, Liang Chen, Jian Ping Gong
SOFT MATTER, 12, 43, 8833, 8840, 2016, [Peer-reviewed]
English, Scientific journal

Coupled instabilities of surface crease and bulk bending during fast free swelling of hydrogels
Riku Takahashi, Yumihiko Ikura, Daniel R. King, Takayuki Nonoyama, Tasuku Nakajima, Takayuki Kurokawa, Hirotoshi Kuroda, Yoshihiro Tonegawa, Jian Ping Gong
SOFT MATTER, 12, 23, 5081, 5088, 2016, [Peer-reviewed]
English, Scientific journal

Self-Adjustable Adhesion of Polyampholyte Hydrogels
Chanchal Kumar Roy, Hong Lei Guo, Tao Lin Sun, Abu Bin Ihsan, Takayuki Kurokawa, Masakazu Takahata, Takayuki Nonoyama, Tasuku Nakajima, Jian Ping Gong
ADVANCED MATERIALS, 27, 45, 7344, +, Dec. 2015, [Peer-reviewed]
English, Scientific journal

Phase-Separation-Induced Anomalous Stiffening, Toughening, and Self-Healing of Polyacrylamide Gels
Koshiro Sato, Tasuku Nakajima, Toshiyuki Hisamatsu, Takayuki Nonoyama, Takayuki Kurokawa, Jian Ping Gong
ADVANCED MATERIALS, 27, 43, 6990, +, Nov. 2015, [Peer-reviewed]
English, Scientific journal

Free Reprocessability of Tough and Self-Healing Hydrogels Based on Polyion Complex
Feng Luo, Tao Lin Sun, Tasuku Nakajima, Takayuki Kurokawa, Abu Bin Ihsan, Xufeng Li, Honglei Guo, Jian Ping Gong
ACS MACRO LETTERS, 4, 9, 961, 964, Sep. 2015, [Peer-reviewed]
English, Scientific journal

Friction of Zwitterionic Hydrogel by Dynamic Polymer Adsorption
Jamil Ahmed, Tetsurou Yamamoto, Honglei Guo, Takayuki Kurokawa, Takayuki Nonoyama, Tasuku Nakajima, Jian Ping Gong
MACROMOLECULES, 48, 15, 5394, 5401, Aug. 2015, [Peer-reviewed]
English, Scientific journal

高強度ゲルをつくる
中島祐, 龔剣萍
高分子, 64, 6, 367, 369, May 2015, [Invited]
Japanese

Oppositely Charged Polyelectrolytes Form Tough, Self-Healing, and Rebuildable Hydrogels
Feng Luo, Tao Lin Sun, Tasuku Nakajima, Takayuki Kurokawa, Yu Zhao, Koshiro Sato, Abu Bin Ihsan, Xufeng Li, Honglei Guo, Jian Ping Gong
ADVANCED MATERIALS, 27, 17, 2722, +, May 2015, [Peer-reviewed]
English, Scientific journal

Polymer Adsorbed Bilayer Membranes Form Self-Healing Hydrogels with Tunable Superstructure
Xufeng Li, Takayuki Kurokawa, Riku Takahashi, Md. Anamul Haque, Youfeng Yue, Tasuku Nakajima, Jan Ping Gong
MACROMOLECULES, 48, 7, 2277, 2282, Apr. 2015, [Peer-reviewed]
English, Scientific journal

Polymer Adsorbed Bilayer Membranes Form Self-Healing Hydrogels with Tunable Superstructure
Xufeng Li, Takayuki Kurokawa, Riku Takahashi, Md. Anamul Haque, Youfeng Yue, Tasuku Nakajima, Jan Ping Gong
MACROMOLECULES, 48, 7, 2277, 2282, Apr. 2015, [Peer-reviewed]
English, Scientific journal

小さな力で多彩な色をだす構造色ゲル―新しいメカノクロミック材料の合成法とその応用
Tasuku Nakajima, Jian Ping Gong
化学, 70, 4, 32, 36, Mar. 2015, [Invited]
Japanese

Swim bladder collagen forms hydrogel with macroscopic superstructure by diffusion induced fast gelation
Md. Tariful Islam Mredha, Xi Zhang, Takayuki Nonoyama, Tasuku Nakajima, Takayuki Kurokawa, Yasuaki Takagid, Jian Ping Gong
JOURNAL OF MATERIALS CHEMISTRY B, 3, 39, 7658, 7666, 2015, [Peer-reviewed]
English, Scientific journal

Quasi-unidirectional shrinkage of gels with well-oriented lipid bilayers upon uniaxial stretching
Tasuku Nakajima, Corentin Durand, Xu Feng Li, Md. Anamul Haque, Takayuki Kurokawa, Jian Ping Gong
SOFT MATTER, 11, 2, 237, 240, 2015, [Peer-reviewed], [Lead author, Corresponding author]
English, Scientific journal

Molecular structure of self-healing polyampholyte hydrogels analyzed from tensile behaviors
Tao Lin Sun, Feng Luo, Takayuki Kurokawa, Sadia Nazneen Karobi, Tasuku Nakajima, Jian Ping Gong
SOFT MATTER, 11, 48, 9355, 9366, 2015, [Peer-reviewed]
English, Scientific journal

In Situ Observation of Ca2+ Diffusion-Induced Superstructure Formation of a Rigid Polyanion
Zi Liang Wu, Riku Takahashi, Daisuke Sawada, Md. Arifuzzaman, Tasuku Nakajima, Takayuki Kurokawa, Jian Hu, Jian Ping Gong
MACROMOLECULES, 47, 20, 7208, 7214, Oct. 2014, [Peer-reviewed]
English, Scientific journal

Crack Blunting and Advancing Behaviors of Tough and Self-healing Polyampholyte Hydrogel
Feng Luo, Tao Lin Sun, Tasuku Nakajima, Takayuki Kurokawa, Yu Zhao, Abu Bin Ihsan, Hong Lei Guo, Xu Feng Li, Jian Ping Gong
MACROMOLECULES, 47, 17, 6037, 6046, Sep. 2014, [Peer-reviewed]
English, Scientific journal

Mechano-actuated ultrafast full-colour switching in layered photonic hydrogels
Youfeng Yue, Takayuki Kurokawa, Md Anamul Haque, Tasuku Nakajima, Takayuki Nonoyama, Xufeng Li, Itsuro Kajiwara, Jian Ping Gong
NATURE COMMUNICATIONS, 5, Aug. 2014, [Peer-reviewed]
English, Scientific journal

Control superstructure of rigid polyelectrolytes in oppositely charged hydrogels via programmed internal stress
Riku Takahashi, Zi Liang Wu, Md Arifuzzaman, Takayuki Nonoyama, Tasuku Nakajima, Takayuki Kurokawa, Jian Ping Gong
NATURE COMMUNICATIONS, 5, Aug. 2014, [Peer-reviewed]
English, Scientific journal

Fracture Process of Microgel-Reinforced Hydrogels under Uniaxial Tension
Jian Hu, Takayuki Kurokawa, Tasuku Nakajima, Zi Liang Wu, Song Miao Liang, Jian Ping Gong
MACROMOLECULES, 47, 11, 3587, 3594, Jun. 2014, [Peer-reviewed]
English, Scientific journal

Sliding Friction of Zwitterionic Hydrogel and Its Electrostatic Origin
Jamil Ahmed, Honglei Guo, Tetsurou Yamamoto, Takayuki Kurokawa, Masakazu Takahata, Tasuku Nakajima, Jian Ping Gong
MACROMOLECULES, 47, 9, 3101, 3107, May 2014, [Peer-reviewed]
English, Scientific journal

一軸配向二分子膜によるハイドロゲルの高靱性化　　　　　　　　　　　　　　　
中島 祐, グン剣萍
超分子研究会アニュアルレビュー, 34, 14, 15, Mar. 2014, [Invited]
Japanese, Scientific journal

Brittle-ductile transition of double network hydrogels: Mechanical balance of two networks as the key factor
Saika Ahmed, Tasuku Nakajima, Takayuki Kurokawa, Md Anamul Haque, Jian Ping Gong
POLYMER, 55, 3, 914, 923, Feb. 2014, [Peer-reviewed]
English, Scientific journal

Proteoglycans and Glycosaminoglycans Improve Toughness of Biocompatible Double Network Hydrogels
Yu Zhao, Tasuku Nakajima, Jing Jing Yang, Takayuki Kurokawa, Jian Liu, Jishun Lu, Shuji Mizumoto, Kazuyuki Sugahara, Nobuto Kitamura, Kazunori Yasuda, A. U. D. Daniels, Jian Ping Gong
ADVANCED MATERIALS, 26, 3, 436, 442, Jan. 2014, [Peer-reviewed]
English, Scientific journal

Geometric and edge effects on swelling-induced ordered structure formation in polyelectrolyte hydrogels
Md. Arifuzzaman, Zi Liang Wu, Riku Takahashi, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong
Macromolecules, 46, 22, 9083, 9090, 26 Nov. 2013, [Peer-reviewed]
English, Scientific journal

Physical hydrogels composed of polyampholytes demonstrate high toughness and viscoelasticity
Tao Lin Sun, Takayuki Kurokawa, Shinya Kuroda, Abu Bin Ihsan, Taigo Akasaki, Koshiro Sato, Md Anamul Haque, Tasuku Nakajima, Jian Ping Gong
NATURE MATERIALS, 12, 10, 932, 937, Oct. 2013, [Peer-reviewed]
English, Scientific journal

Lamellar hydrogels with high toughness and ternary tunable photonic stop-band
You Feng Yue, M. Anamul Haque, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong
Advanced Materials, 25, 22, 3106, 3110, 11 Jun. 2013, [Peer-reviewed]
English, Scientific journal

Synthesis and Fracture Process Analysis of Double Network Hydrogels with a Well-Defined First Network
Tasuku Nakajima, Yuki Fukuda, Takayuld Kurokawa, Takamasa Sakai, Ung-il Chung, Jian Ping Gong
ACS MACRO LETTERS, 2, 6, 518, 521, Jun. 2013, [Peer-reviewed]
English, Scientific journal

Double network hydrogels from polyzwitterions: high mechanical strength and excellent anti-biofouling properties
Haiyan Yin, Taigo Akasaki, Tao Lin Sun, Tasuku Nakajima, Takayuki Kurokawa, Takayuki Nonoyama, Toshio Taira, Yoshiyuki Saruwatari, Jian Ping Gong
JOURNAL OF MATERIALS CHEMISTRY B, 1, 30, 3685, 3693, 2013, [Peer-reviewed]
English, Scientific journal

Characterization of internal fracture process of double network hydrogels under uniaxial elongation
Tasuku Nakajima, Takayuki Kurokawa, Saika Ahmed, Wen-li Wu, Jian Ping Gong
SOFT MATTER, 9, 6, 1955, 1966, 2013, [Peer-reviewed], [Lead author]
English, Scientific journal

A phase diagram of neutral polyampholyte - from solution to tough hydrogel
Abu Bin Ihsan, Tao Lin Sun, Shinya Kuroda, Md. Anamul Haque, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong
JOURNAL OF MATERIALS CHEMISTRY B, 1, 36, 4555, 4562, 2013, [Peer-reviewed]
English, Scientific journal

High Fracture Efficiency and Stress Concentration Phenomenon for Microgel-Reinforced Hydrogels Based on Double-Network Principle
Jian Hu, Takayuki Kurokawa, Tasuku Nakajima, Tao Lin Sun, Tiffany Suekama, Zi Liang Wu, Song Miao Liang, Jian Ping Gong
MACROMOLECULES, 45, 23, 9445, 9451, Dec. 2012, [Peer-reviewed]
English, Scientific journal

A Universal Molecular Stent Method to Toughen any Hydrogels Based on Double Network Concept
Tasuku Nakajima, Hitomi Sato, Yu Zhao, Shinya Kawahara, Takayuki Kurokawa, Kazuyuki Sugahara, Jian Ping Gong
ADVANCED FUNCTIONAL MATERIALS, 22, 21, 4426, 4432, Nov. 2012, [Peer-reviewed], [Lead author]
English, Scientific journal

Structure Optimization and Mechanical Model for Microgel-Reinforced Hydrogels with High Strength and Toughness
Jian Hu, Takayuki Kurokawa, Kenta Hiwatashi, Tasuku Nakajima, Zi Liang Wu, Song Miao Liang, Jian Ping Gong
MACROMOLECULES, 45, 12, 5218, 5228, Jun. 2012, [Peer-reviewed]
English, Scientific journal

Effect of Void Structure on the Toughness of Double Network Hydrogels
Tasuku Nakajima, Hidemitsu Furukawa, Yoshimi Tanaka, Takayuki Kurokawa, Jian Ping Gong
JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 49, 17, 1246, 1254, Sep. 2011, [Peer-reviewed], [Lead author]
English, Scientific journal

Water-Induced Brittle-Ductile Transition of Double Network Hydrogels
Hiroko Itagaki, Takayuki Kurokawa, Hidemitsu Furukawa, Tasuku Nakajima, Yukiteru Katsumoto, Jian Ping Gong
MACROMOLECULES, 43, 22, 9495, 9500, Nov. 2010, [Peer-reviewed]
English, Scientific journal

A facile method for synthesizing free-shaped and tough double network hydrogels using physically crosslinked poly(vinyl alcohol) as an internal mold
Tasuku Nakajima, Naoyuki Takedomi, Takayuki Kurokawa, Hidemitsu Furukawa, Jian Ping Gong
POLYMER CHEMISTRY, 1, 5, 693, 697, Jul. 2010, [Peer-reviewed], [Lead author]
English, Scientific journal

A Deformation Mechanism for Double-Network Hydrogels with Enhanced Toughness
Tasuku Nakajima, Hidemitsu Furukawa, Jian Ping Gong, Eric K. Lin, Wen-li Wu
POLYMER NETWORKS: SYNTHESIS, PROPERTIES, THEORY AND APPLICATIONS, 291-292, 1, 122, +, 2010, [Peer-reviewed], [Lead author]
English, International conference proceedings

True Chemical Structure of Double Network Hydrogels
Tasuku Nakajima, Hidemitsu Furukawa, Yoshimi Tanaka, Takayuki Kurokawa, Yoshihito Osada, Jian Ping Gong
MACROMOLECULES, 42, 6, 2184, 2189, Mar. 2009, [Peer-reviewed], [Lead author]
English, Scientific journal

Brittle, ductile, paste-like behaviors and distinct necking of double network gels with enhanced heterogeneity
Yasunori Kawauchi, Yoshimi Tanaka, Hidemitsu Furukawa, Takayuki Kurokawa, Tasuku Nakajima, Yoshihito Osada, Jian Ping Gong
Journal of Physics: Conference Series, 184, 012016, Institute of Physics Publishing, 2009, [Peer-reviewed]
English, International conference proceedings

SUPER TOUGH GELS WITH A DOUBLE NETWORK STRUCTURE
Tasuku Nakajima, Takayuki Kurokawa, Hidemitsu Furukawa, Qiu Ming Yu, Yoshimi Tanaka, Yoshihito Osada, Jian Ping Gong
CHINESE JOURNAL OF POLYMER SCIENCE, 27, 1, 1, 9, Jan. 2009, [Peer-reviewed], [Invited], [Lead author]
English, Scientific journal

Importance of entanglement between first and second components in high-strength double network gels
Mei Huang, Hidemitsu Furukawa, Yoshimi Tanaka, Tasuku Nakajima, Yoshihito Osada, Jian Ping Gong
MACROMOLECULES, 40, 18, 6658, 6664, Sep. 2007, [Peer-reviewed]
English, Scientific journal

Creation of hydrogels with ultra high mechanical strength [XII]: The effect of controlled void structure　　　　　　　　　　　　　　　
Tasuku Nakajima, Hidemitsu Furukawa, Yoshimi Tanaka, Takayuki Kurokawa, Jian Ping Gong, Yoshihito Osada
Polymer Preprints, Japan, 55, 2, 3212, 3213, 2006
Japanese, International conference proceedings

新陳代謝して成長するゲル
中島祐, GONG Jian Ping, 化学と教育, 69, 3, 2021

Self-Growing Gels Inspired by Biological Metabolism
中島祐, 中島祐, 繊維学会予稿集(CD-ROM), 76, 1, 2021

いきものみたいなもの「栄養」を取り込んで成長するゲル
中島祐, 高分子, 69, 4, 2020

Anisotropic Bilayer-hybrid Gels: Fabrication and Water Induced Rubbery-Glassy Transition
ILYAS Muhammad, HAQUE Md Anamul, YUE Youfeng, KUROKAWA Takayuki, NAKAJIMA Tasuku, NONOYAMA Takayuki, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 67, 2, 2018

Water Triggered Ductile-Brittle Transition of Anisotropic Lamellar Hydrogels
ILYAS Muhammad, HAQUE Md Anamul, YUE Youfeng, KUROKAWA Takayuki, NAKAJIMA Tasuku, NONOYAMA Takayuki, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 66, 2, 2017

固体内部からのGraft‐gelationによる高靱性ゲルの固体表面へのコーティング
塩本健悟, 中島祐, 黒川孝幸, GONG Jang Ping, 高分子学会予稿集(CD-ROM), 63, 1, ROMBUNNO.1PC061, 09 May 2014
Japanese

DNゲルの強靱性に対する数理的考察
井倉弓彦, 中島祐, 野々山貴行, 黒川孝幸, GONG Jian Ping, 長山雅晴, 高分子学会予稿集(CD-ROM), 63, 1, ROMBUNNO.2PD046, 09 May 2014
Japanese

軟骨再生ハイドロゲルと骨組織の接着を目指した高靱性DNゲル表面におけるHApのバイオミネラリゼーション
木山竜二, 野々山貴行, 黒川孝幸, 中島祐, GONG Jian Ping, 日本セラミックス協会年会講演予稿集(CD-ROM), 2014, ROMBUNNO.1P141, 07 Mar. 2014
Japanese

高強度ハイドロゲルとバイオセラミックスの融合:ソフトセラミックスの創製
野々山貴行, 木山竜二, 黒川孝幸, 中島祐, GONG Jian Ping, 日本セラミックス協会年会講演予稿集(CD-ROM), 2014, ROMBUNNO.1J24, 07 Mar. 2014
Japanese

ゲルの異方的膨潤が誘起する液晶性高分子の超構造形成
高橋陸, 中島祐, 黒川孝幸, 野々山貴行, グン剣萍, 化学系学協会北海道支部冬季研究発表会講演要旨集(CD-ROM), 2014, ROMBUNNO.P38, 28 Jan. 2014
Japanese

Double network構造を有する強靭エラストマーの創製
米田有希, 中島祐, 黒川孝幸, 佐田和己, 小門憲太, ぐん剣萍, 化学系学協会北海道支部冬季研究発表会講演要旨集(CD-ROM), 2014, ROMBUNNO.P39, 28 Jan. 2014
Japanese

ゲル‐固体間の強靭な接着を目指した,重合開始点を含有する基板からのゲル重合
塩本健悟, 岡崎春香, 中島祐, 黒川孝幸, ぐん剣萍, 化学系学協会北海道支部冬季研究発表会講演要旨集(CD-ROM), 2014, ROMBUNNO.2A09, 28 Jan. 2014
Japanese

配向したラメラ構造を有するゲルの異常変形挙動
中島祐, HAQUE Md. Anamul, 黒川孝幸, GONG Jian Ping, 高分子ゲル研究討論会講演要旨集, 25th, 31, 32, 15 Jan. 2014
Japanese

Controlled and Selective Swelling of an Anisotropic Hydrogel by Restricted Diffusion of Water
HAQUE Md. Anamul, UCHIUMI Maki, YOUFENG Yue, KUROKAWA Takayuki, NAKAJIMA Tasuku, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 61, 1, 2012

Fracture Behavior of an Anisotropic Hydrogel Containing Nano-Scale Bilayer with Macro-scale Ordering
HAQUE Md. Anamul, KUROKAWA Takayuki, NAKAJIMA Tasuku, YUE Youfeng, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 61, 1, 2012

Effect of Water Content on the Mechanical Properties of an Anisotropic Hydrogel Containing Macro-sacle Bilayer
HAQUE Md. Anamul, KUROKAWA Takayuki, NAKAJIMA Tasuku, YUE Youfeng, AHMED Saika, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 61, 2, 2012

Fracture Behavior of an Anisotropic Hydrogel Containing Nano-Scale Bilayer with Macro-scale Ordering
HAQUE Md. Anamul, KUROKAWA Takayuki, NAKAJIMA Tasuku, YUE Youfeng, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 61, 2, 2012

新規両親媒性ソルバトクロミック蛍光色素の合成とその応用~形状記憶ゲルの観察~
古橋由梨, 中島祐, 黒川孝幸, 黒川孝幸, 古川英光, 山田幸司, GONG Jian Ping, 高分子ゲル研究討論会講演要旨集, 22nd, 2011

新規両親媒性ソルバトクロミック蛍光色素の合成とその応用~高分子水溶液とゲルの構造変化観察~
古橋由梨, 中島祐, 黒川孝幸, 黒川孝幸, 古川英光, 山田幸司, ぐん剣萍, 高分子学会北海道支部研究発表会講演要旨集, 45th, 2011

超高強度ダブルネットワークゲルの創製とその高強度化メカニズム(<特集>ゲル研究の新展開)
中島 祐, 〓 剣萍, 物性研究, 93, 5, 551, 557, 05 Feb. 2010
物性研究刊行会, Japanese

力学的ヒステリシスと膨潤度から見る,DNゲルの破壊挙動
中島祐, 中島祐, YU Qiu Ming, 田中良巳, 田中良巳, 黒川孝幸, 黒川孝幸, 古川英光, 古川英光, GONG Jian Ping, LIN Eric, WU Wen-li, 高分子ゲル研究討論会講演要旨集, 21st, 2010

超高強度Double-Networkゲルの創製(XXII):延伸性が高破壊エネルギーに与える影響
YU Qiu Ming, 黒川孝幸, 黒川孝幸, 中島祐, 古川英光, 田中良巳, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 59, 1 Disk1, 2010

蛍光プローブによるハイドロゲルのラジカル重合過程の観察
古橋由梨, 中島祐, 黒川孝幸, 黒川孝幸, 古川英光, 山田幸司, GONG jian Ping, 高分子学会予稿集(CD-ROM), 59, 1 Disk1, 2010

超高強度ゲルの創製XXV]:一軸伸長下におけるDNゲルの内部破壊挙動の考察
中島祐, YU Qiu Ming, 黒川孝幸, 黒川孝幸, 古川英光, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 59, 2 Disk1, 2010

新規両親媒性ソルバトクロミック蛍光色素の合成とその応用~高分子水溶液の構造変化の観察~
古橋由梨, 中島祐, 黒川孝幸, 黒川孝幸, 古川英光, 山田幸司, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 59, 2 Disk1, 2010

高強度DNゲルの開発と関節軟骨再生誘導への応用 (特集 生体材料の最新開発動向)
中島 祐, ぐん ちぇんぴん, 安田 和則, 工業材料, 57, 6, 38, 41, Jun. 2009
日刊工業出版プロダクション, Japanese

高強度ハイドロゲルのコーティングと固体基板との高強度接着
桜井翔太, 古川英光, 中島祐, 黒川孝幸, 田中良巳, GONG Jian Ping, 高分子ゲル研究討論会講演要旨集, 20th, 2009

DNゲルの高強度化メカニズム
大井彰, 中島祐, 黒川孝幸, 古川英光, 田中良巳, きょう剣萍, 高分子学会北海道支部研究発表会講演要旨集, 43rd, 2009

超高強度ゲルの創製(XXI)静・動的光散乱によるDNゲルのダメージゾーンの研究
YU Qiu Ming, 古川英光, 古川英光, 田中良巳, 田中良巳, 中島祐, 黒川孝幸, 黒川孝幸, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 58, 2 Disk1, 2009

DNゲルの強度に対する水の効果~FT-IRによるゲル-溶媒間相互作用解析~
板垣裕子, 中島祐, 勝本之晶, 黒川孝幸, 黒川孝幸, 古川英光, 古川英光, GONG Jian Ping, 高分子学会予稿集(CD-ROM), 58, 2 Disk1, 2009

超高強度ゲルの創製[XVII]:両網目の協同性
中島祐, 古川英光, 田中良巳, 黒川孝幸, GONG Jian Ping, 長田義仁, 高分子ゲル研究討論会講演要旨集, 19th, 2008

超高強度DNゲルの高強度化条件探索
中島祐, 古川英光, 田中良巳, 黒川孝幸, GONG Jian Ping, 長田義仁, 高分子学会北海道支部研究発表会講演要旨集, 42nd, 2008

Creation of Double Network Hydrogels with Extremely High Strength and Its Anomalous Fracture Mechanism
Tasuku Nakajima, Yoshimi Tanaka, Hidemitsu Furukawa, Takayuki Kurokawa, Jian Ping Gong, KOBUNSHI RONBUNSHU, 65, 12, 707, 715, 2008
Japanese

20aRE-7 High-Strength Soft & Wet Matter (3) : Entanglement Effect in Double-Network Gels
Furukawa Hidemitsu, Huang Mei, Nakajima Tasuku, Tanaka Yoshimi, Kurokawa Takayuki, Gong Jian Ping, Osada Yoshihito, Meeting abstracts of the Physical Society of Japan, 62, 1, 346, 346, 28 Feb. 2007
The Physical Society of Japan (JPS), Japanese

超高強度ゲルの創製[XVI]:Truly Independent Double Network gelと不均一構造との関係性
中島祐, 川内保範, 古川英光, 田中良巳, 黒川孝幸, GONG Jian Ping, 長田義仁, 高分子学会予稿集(CD-ROM), 56, 2 Disk1, 2007

疎密構造の制御によるDouble Networkゲルの高強度化
中島祐, 川内保範, 古川英光, 田中良巳, 黒川孝幸, きょう剣萍, きょう剣萍, 長田義仁, 高分子学会北海道支部研究発表会講演要旨集, 41st, 2007

超高強度ゲルの創製[XIV]:疎密構造が誘起するDNゲルのNecking現象
中島祐, 古川英光, 川内保範, 田中良巳, 黒川孝幸, GONG Jian Ping, GONG Jian Ping, 長田義仁, 高分子学会予稿集(CD-ROM), 56, 1 Disk1, 2007

超高強度ゲルの創製[XII]制御されたvoid構造の効果
中島祐, 古川英光, 田中良巳, 黒川孝幸, GONG Jian Ping, GONG Jian Ping, 長田義仁, 高分子学会予稿集(CD-ROM), 55, 2 Disk1, 2006

Design of Low Entropy Polymer Network Materials for Unique Functions
Grants-in-Aid for Scientific Research
20 Dec. 2022 - 31 Mar. 2029
グン 剣萍, Li Xiang, 野々山 貴行, 中島 祐
Japan Society for the Promotion of Science, Fund for the Promotion of Joint International Research (International Leading Research ), Hokkaido University, 22K21342

Design engineering for outstanding materials with controlled soft-stiff heterogeneity
Grants-in-Aid for Scientific Research
01 Apr. 2024 - 31 Mar. 2027
篠崎 健二, 加藤 和明, 中島 祐, 菊池 将一
Japan Society for the Promotion of Science, Grant-in-Aid for Transformative Research Areas (B), National Institute of Advanced Industrial Science and Technology, 24H00844

Metabolic Material System: Material Growth by Metabolic-like Destruction and Remodeling
Grants-in-Aid for Scientific Research
27 Apr. 2022 - 31 Mar. 2027
グン 剣萍, 中島 祐, 印出井 努, 野々山 貴行
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (S), Hokkaido University, 22H04968

Establishment of a framework for self-evolving materials through mechanical training
Grants-in-Aid for Scientific Research
01 Apr. 2022 - 31 Mar. 2025
グン 剣萍, 印出井 努, 野々山 貴行, キング ダニエル, 中島 祐
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A), Hokkaido University, 22H00327

未踏高分子材料群「極限伸長網目」の学理構築
戦略的な研究開発の推進 戦略的創造研究推進事業 さきがけ
2020 - 2023
中島 祐
ゲル・ゴムなどのソフト高分子網目材料は、そのナノスケール網目鎖のコイル状構造に由来した柔軟性、伸張性を示します。本研究では、これら材料の網目鎖を極度に伸長させ、新奇力学機能を有する未踏材料「極限伸長網目」を創製します。自由エネルギー的に不利な極限伸長網目の合成法を確立し、そのナノ伸長構造に由来する特異な力学特性を見出します。得られた材料は、易分解材料、力で機能化する材料などへの応用展開を図ります。
科学技術振興機構, 北海道大学, Principal investigator

Utilizing the Sacrificial Bonding Principle to Create Soft-Hard Composites with Toughness that Surpasses Metals and Novel Functions
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S)
31 May 2017 - 31 Mar. 2022
グン 剣萍, 黒川 孝幸, 野々山 貴行, キング ダニエル, 中島 祐
本年度は主に、ハードマター相の犠牲結合が複合材料の強靭化に及ぼす効果を解明した。最初に、mmスケールの多様な二次元長方格子（犠牲結合）を設計し、高性能3Dプリンターによって作製した。次いで、高靱性の柔らかい材料をマトリックス相として格子と複合させ、巨視的なスケールでのダブルネットワーク複合体を創製した。二次元格子の骨格の太さを制御した実験より、引張試験における多段階の格子の破断（すなわち犠牲結合原理の発現）は、二次元格子の強度がマトリックスの強度を上回った場合に生じることが分かった。また格子の節の数を制御した実験より、節の数を増やすほど引張試験時における格子の破断イベント数が増えるために材料が強靭となるが、強靭性はある一定の値で頭打ちになることが分かった。さらに多様な材質による二次元格子を検討した結果、どのような材質を用いても複合材料は強靭になったことから、格子の化学的性質（例えば表面の接着性）は強靭化に大きな影響を及ぼさず、格子とマトリックスの力学物性の関係性が強靭化度合の決定の主要因であることが明らかとなった。
次いで、多様な二次元・三次元格子を設計し、格子のポアソン比を変化させた複合材料を創製した。骨格として、具体的には負のポアソン比を持つオーセチック構造や、正のポアソン比を持つハニカム構造などを用いた。引張試験結果より、複合材料の強度は格子とマトリックスのポアソン比のミスマッチが大きいほど高くなることが示唆された。偏光顕微鏡観察の結果、本現象は、複合材料の変形時、ポアソン比のミスマッチによりマトリックスが局所的に（巨視的な変形よりも）極めて大きく変形することによって引き起こされていることが示唆された。また、ポアソン比のミスマッチによりマトリックスが（通常では起こりえない）体積変形を強いられることも原因の１つではないかと考えられ、現在検証を進めている。
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (S), Hokkaido University, 17H06144

Experimental investigation of single polymer chain mechanics via analysis of mechanical analysis of gels
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A)
01 Apr. 2017 - 31 Mar. 2021
NAKAJIMA TASUKU
Mechanical properties of polymeric materials are mainly determined by mechanical properties of polymer chains inside. Thus, experimental determination of mechanical properties of single polymer chain is important for widespread applications of polymeric materials. However, experimental techniques to measure the properties of single polymer chain have been still in development. In this study, we succeeded in extracting the mechanical properties of single polymer chain, especially its extremely stretched state, by analyzing the stretching and swelling tests of the macroscale polymer gels.
Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (A), Hokkaido University, 17H04891

Creation of soft/hard complex materials tougher than metal based on the
Grants-in-Aid for Scientific Research
01 Apr. 2017 - 31 Mar. 2018
グン 剣萍, 黒川 孝幸, 中島 祐, 野々山 貴行, キング ダニエル
本研究では、高靭性ゲルの力学挙動（引張試験で見られる降伏現象、弾性率の低下を伴うヒステリシス現象、および引裂試験で見られる亀裂周辺の降伏領域(内部破壊領域)の形成）の三つの特徴を評価することによって、ゲルの靭性及びその高靭性化機構を解明することを目的とした。研究機関内には、ポリアンフォライトゲル/グラスファイバー織物の複合体について、様々な幅のサンプルを作製して引裂試験を行い、破壊エネルギーと降伏領域の関係を見積もった。サンプルの幅が降伏領域のサイズ（~cm）より小さい場合、複合体の破壊エネルギーはサンプルの幅と正の相関があった。一方、サンプルの幅が降伏領域より大きい場合、複合体の破壊エネルギーはサンプルの幅に依存しなかった。これは、本複合体の異常に高い破壊エネルギーが、亀裂近傍の降伏領域形成によるエネルギー散逸によることを強く示唆する結果である。また、破壊されたサンプルを走査型電子顕微鏡で観察した結果、繊維近傍におけるゲル層の破壊が確認された。ここから、本複合体の変形時には、ゲル-繊維間の応力伝達により、ゲル層の変形と破壊によるエネルギー散逸が高効率で発生し、それが本複合体を高効率にタフ化していることが示唆された。
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A), Hokkaido University, 17H01222

Creation of Tough Elastomer Based on DN Principle for Toughening of Hydrogels
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
01 Apr. 2014 - 31 Mar. 2017
NAKAJIMA Tasuku
Elastomer is unique and exclusive solid due to its anomalous softness and extensibility. For toughening of rubbers, dispersion of filler has been exclusively applied for a long time. However, recently significant improvement of elastomer toughness by this method has no longer been reported because this traditional method had been already studied for a long period. On the other hand, our group has created double network (DN) hydrogels with extremely high toughness comparable to industrial rubbers, despite 90wt% of water content. Tough DN gels are comprised of the two independent networks, which are brittle 1st and ductile 2nd networks. Note that gels and elastomers are essentially same in the mechanical viewpoint; mechanical behavior of both of them follows rubber elasticity theory. Inspired by the DN gel studies, in this research project I have created a series of tough elastomer by introduction of contrasting double network structure.
Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B), Hokkaido University, 26870008

Proof of the Universality of Sacrificial Bond Principle and Creation of Tough Functional Hydrogels with Variety of Sacrificial Bonds
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (S)
31 May 2012 - 31 Mar. 2017
Gong Jian Ping, NONOYAMA Takayuki, SUN Taolin
Gels have been anticipated as tissue-like functional materials, but generally they are mechanically too weak to be applied widely. On the other hand, recently our group
has proposed "sacrificial bond principle", where toughness of gels can be effectively improved by introducing weak and brittle bonds into soft and stretchable networks. In this project, we have created a series of extremely tough gels using this principle, e.g., variants of double network gels
featuring covalent sacrificial bonds, polyampholyte gels containing ionic sacrificial bonds, and phase-separated polyacrylamide gels exhibiting super toughness based on solvophobic sacrificial bonds. We have also succeeded in adding functions corresponding to chemical species of sacrificial bonds to the tough gels, e.g., self-healing properties to polyampholyte gels and bioactivity to double network gels containing biopolymers. Through these studies, we have confirmed generality and diversity of sacrificial bond principle.
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (S), Hokkaido University, 24225006

「犠牲結合原理」の普遍性の証明と多様な犠牲結合による高靭性ゲルの創製
科学研究費助成事業
2012 - 2012
グン 剣萍, 黒川 孝幸, 中島 祐
本研究では、高靭性ゲルの力学挙動(引張試験で見られる降伏現象、弾性率の低下を伴うヒステリシス現象、および引裂試験で見られる亀裂周辺の降伏領域(内部破壊領域)の形成)の三つの特徴を評価することによって、ゲルの靭性及びその高靭性化機構を解明することを目的とする。具体的には、多様な犠牲結合構造を導入したゲルに対して、引張試験で降伏応力、ヒステリシス面積および変形前後の弾性率の変化、引裂試験で破壊エネルギーを測定し、ゲルに導入した犠牲結合の密度との関係を定量化した。さらに、引裂試験時における亀裂周辺の降伏領域の厚さをレーザー顕微鏡で測定し、破壊された犠牲結合と破壊エネルギーとの相関を調べた。
日本学術振興会, 基盤研究(A), 北海道大学, 24245042

高分子ステント法による、超高強度ダブルネットワークゲルの高強度化手法の一般化
Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows
2010 - 2011
中島 祐
昨年度は本分子ステント法の基礎技術を確立し、あらゆる親水性ポリマーから高強度St-DNゲルが創成可能であることを示した。そこで本年度は、本方法を様々な系へと拡張し、新規機能性高強度ゲルの開発を目指した。最初に、疎水性高分子を1st networkとした高強度ハイドロゲルの創製を行った。本ゲルは、一般的なDNゲルと同様に高い強度を示した他、ハイドロゲルでありながら水に対する高い接触角(80°)を示した。次に、配向高分子フィルムを作製し、これを1st networkに用いることで、物性に異方性のあるSt-DNゲルを合成した。本ゲルは、配向フィルムの構造を反映し、一軸に膨潤する、一方向のみに引き裂き可能などの興味深い新規物性を示した。以上より、疎水性高分子を基にした新規機能性DNゲルの開発に成功した。本結果は、DNゲルの高強度化手法を更に拡張し、従来は実現できなかった機能を発現させたという点で画期的である。また、ステントによるゲル膨潤挙動の理論的な考察を行った。中性ゲルに強電解質高分子(ステント)を導入すると、ステントの持つ高い浸透圧のためにゲルは膨潤する。ステント濃度が0.5Mに達するまでは、ゲルの膨潤挙動は一般的なゲル膨潤理論で説明可能であった。一方、ステント濃度が0.5M以上になると、ゲルの実際の膨潤度は理論値を下回った。本現象は、ステント濃度が大きい時、1st networkゲルの分子鎖の伸び切りが起こっていることを示している。また、本ゲルを基にSt-DNゲルを合成したところ、ステント濃度が0.5M以下の場合、ゲルの力学強度はステント濃度の増加に伴って大きくなるが、0.5M以上ではほぼ同じであった。ここから、St-DNゲルは1st networkが伸び切っているときに高強度化されることが示唆された。以上の成果を基に、現在4編の論文を投稿、あるいは執筆中である。
Japan Society for the Promotion of Science, Grant-in-Aid for JSPS Fellows, Hokkaido University, 10J02317