Papers

• Reproducibility of glycocheck measurements in patients under general anesthesia with muscle relaxants: A prospective observational study
  Takayuki Toki, Kazuyuki Mizunoya, Takashi Soejima, Yasunori Yagi, Naoko Nakamine, Yusuke Itosu, Ryo Takagi, Isao Yokota, Yuji Morimoto
  Journal of Clinical Monitoring and Computing, Springer Science and Business Media LLC, 10 Jul. 2025, [Peer-reviewed], [International Magazine]
  English, Scientific journal
• Differences of cerebral oxygen saturation in dialysis patients: a comparison of three principals of near infrared spectroscopy.
  Yasunori Yagi, Yasunori Kubo, Koji Hoshino, Kazufumi Okada, Kiyohiko Hotta, Nobuo Shinohara, Yuji Morimoto
  Journal of anesthesia, 37, 6, 861, 867, Dec. 2023, [Domestic magazines]
  English, Scientific journal, PURPOSE: It has been reported that cerebral oxygen saturation (rSO2) measured by near infrared spectroscopy is low in dialysis patients. We compared the rSO2 values of dialysis patients before living donor kidney transplantation and their donors as controls by using three spectroscopes that utilize different principals, the INVOS 5100C (spatially resolved spectroscopy), FORE-SIGHT ELITE (modified Beer-Lambert law) and tNIRS-1 (time-resolved spectroscopy). METHODS: Before induction of anesthesia, the sensors of one of the three spectroscopes were placed on the forehead and rSO2 values were recorded followed by the same measurement using the other two spectroscopes. The primary objective was to compare the rSO2 values of the dialysis patients and controls using the three spectroscopes by the unpaired t test. Then we compared the rSO2 values among the spectroscopes in both dialysis patients and controls by one-way ANOVA. Finally, we examined the relations between the rSO2 values and the physiological values by using the Pearson correlation coefficient. RESULTS: Fifteen pairs of dialysis patients and controls were studied. With the INVOS 5100 C, the values of the dialysis patients (59.7 ± 9.7% (mean ± standard deviation) were 13% lower than those of the controls (73.3 ± 6.9%) (P < 0.01). With the tNIRS-1, the values were 57.8 ± 4.8% in the dialysis patients and 63.3 ± 3.5% in the controls (P < 0.01). Almost no differences were observed with the FORE-SIGHT ELITE (71.6 ± 4.9% [dialysis patients] vs. 70.8 ± 4.3% [Controls]) (P = 0.62). Among the spectroscopes, the values were significantly different in both dialysis patients and controls. For the INVOS 5100C and tNIRS-1, correlation coefficients between rSO2 values and blood Hb and serum Alb were more than 0.5. CONCLUSIONS: The rSO2 values for comparisons between the dialysis patients and the controls were different according to differences of the principles of the near infrared spectroscopes. In the INVOS 5100C and tNIRS-1, rSO2 values may be related to blood Hb and serum Alb.
• Intraoperative myocardial infarction and refractory cardiogenic shock during major hepatectomy: a case report
  Yasunori Yagi, Kazuyuki Mizunoya, Toshihiro Mori, Hitoshi Saito, Yuji Morimoto
  JA Clinical Reports, 8, 1, Springer Science and Business Media LLC, Dec. 2022, [Lead author], [Domestic magazines]
  Scientific journal, Abstract
  
  Background
  
  Myocardial infarction (MI) complicated by cardiogenic shock during non-cardiac surgery is a rare but fatal complication. The management of intraoperative MI is challenging.
  
  Case presentation
  
  A 77-year-old hypertensive man with good functional capacity was scheduled for hepatectomy. After the start of liver resection, the electrocardiogram monitor showed ST depression, and the patient developed refractory cardiogenic shock. Transesophageal echocardiography revealed severe hypokinesis of the anteroseptal wall. The surgery was suspended, and an intra-aortic balloon pump was placed following immediate abdominal closure. Coronary angiography revealed severe stenosis of the left main coronary trunk, and percutaneous coronary intervention (PCI) was performed. Myocardial wall motion improved, and blood pressure stabilized. Two days after PCI, hepatectomy, which had been suspended, was successfully completed.
  
  Conclusions
  
  Once intraoperative MI has occurred, early diagnosis and multidisciplinary approaches are important to manage the difficult clinical situation.
• Altered microvascular reactivity assessed by near-infrared spectroscopy after hepato-pancreato-biliary surgery
  Kazuyuki Mizunoya, Yasunori Yagi, Yuji Morimoto, Satoshi Hirano
  Journal of Clinical Monitoring and Computing, 36, 3, 703, 712, Springer Science and Business Media LLC, Jun. 2022, [International Magazine]
  Scientific journal
• Diagnostic timing dependent characteristics of acute kidney injury following hepatectomy: a retrospective historical cohort analysis
  Kazuyuki Mizunoya, Yasunori Yagi, Hirofumi Kamachi, Toshiya Kamiyama, Yuji Morimoto, Akinobu Taketomi
  HPB, 23, 12, 1897, 1905, Elsevier BV, Dec. 2021, [International Magazine]
  Scientific journal
• Anesthetic management by blockage of thoracoabdominal nerves through perichondrial approach (TAPA) for open nephrectomy in a pediatric patient with Wilms tumor
  Nobuhiro Tanaka, Yasunori Yagi, Katsuhiro Aikawa, Yuji Morimoto
  Journal of Clinical Anesthesia, 59, 51, 52, Elsevier BV, Feb. 2020, [International Magazine]
  Scientific journal
• Changes of Cerebral Oxygenation in Sequential Glenn and Fontan Procedures in the Same Children
  Yasunori Yagi, Masataka Yamamoto, Hitoshi Saito, Toshihiro Mori, Yuji Morimoto, Takayoshi Oyasu, Tsuyoshi Tachibana, Yoichi M. Ito
  Pediatric Cardiology, 38, 6, 1215, 1219, Springer Science and Business Media LLC, Aug. 2017, [International Magazine]
  Scientific journal