Hashimoto Shigeru

Institute for Genetic Medicine Molecular PathogenesisAssociate Professor
Institute for Integrated Innovations Institute for Vaccine Research and DevelopmentAssociate Professor
Last Updated :2025/06/07

■Researcher basic information

Degree

  • Doctor of Philosophy, Osaka University

Researchmap personal page

Research Keyword

  • 細胞生物学
  • 分子生物学
  • cellular biology
  • molecular biology

Research Field

  • Life sciences, Molecular biology

Educational Organization

■Research activity information

Other Activities and Achievements

  • GeP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion
    Masaki Morishige, Shigeru Hashimoto, Eiji Ogawa, Yoshinobu Toda, Hirokazu Kotani, Mayumi Hirose, Shumei Wei, Ari Hashimoto, Atsuko Yamada, Hajime Yano, Yuichi Mazaki, Hiroshi Kodama, Yoshinori Nio, Toshiaki Manabe, Hiromi Wada, Hidenori Kobayashi, Hisataka Sabe, NATURE CELL BIOLOGY, 10, 1, 85, U70, Jan. 2008
    English
  • A new paxillin-biuding protein, PAG3/Pap α/ KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recrnitment to focal adhesions and all migration               
    Moleanlar Biology of the Cell, 11, 4, 1315, 1327, 2000
  • Paxillim isoforms in mowse. Lack of the l islorm and developmeutally speciled βisoform expression.               
    Jonrual of Biological chemistry, 273, 22435, 22441, 1998
  • 単球及び癌細胞でのパキシリンアイソフォームの発現と結合タンパク質の解析(共著)               
    生化学雑誌, 272, 7432, 7444, 1997
  • Monocyte cells and cancer cells express novel paxillin isoforms with different binding
    Journal of Biological Chemistry, 272, 11, 7437, 7444, 1997
  • 酵母TFIIDの変異体を用いた酸性転写活性化因子GAL4-VP16による転写活性化機構の解析(共著)               
    自然, 369, 252, 255, 1994
  • Yeast TFIID point mutants defective in activation by acidic activator GAL4-VP16               
    Nature, 369, 252, 255, 1994
  • インターロイキン6遺伝子転写調節因子(NF-IL6)(共著)               
    化学免疫, 51, 299, 322, 1992
  • A NUCLEAR FACTOR FOR THE IL-6 GENE (NF-IL6)
    S AKIRA, H ISSHIKI, T NAKAJIMA, S KINOSHITA, Y NISHIO, S HASHIMOTO, S NATSUKA, T KISHIMOTO, CHEMICAL IMMUNOLOGY, 51, 299, 322, 1992
    English, Book review

Affiliated academic society

  • 日本分子生物学会               
  • 日本癌学会               

Research Themes

  • 癌細胞の浸潤形質獲得過程の解明               
    Competitive research funding
  • Analysis of the regulation mechanisms for the acquisition of invasive phenotype of tumor cells               
    Competitive research funding