Uji-i Hiroshi
| Research Institute for Electronic Science Photonics and Optical Science | Professor |
Last Updated :2025/06/07
■Researcher basic information
Profile Information
- Hiroshi Uji-i (Ph.D.-Science) is a Research professor of chemistry department at KU Leuven (Belgium) and a full professor of Research Institute for Electronic Science at Hokkaido University (Japan). He received his B Sc and M Sc in Applied physics at Osaka University (Japan), and PhD in chemistry at Tohoku University (Japan).
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Educational Organization
- Master's degree program, Graduate School of Information Science and Technology
- Doctoral (PhD) degree program, Graduate School of Information Science and Technology
■Career
Career
- Jul. 2015 - Present
Hokkaido University, Research Institute for Electronic Science, Full professor - Oct. 2011 - Present
KU Leuven, Department of Chemistry, Research professor - Sep. 2004 - Sep. 2011
KULeuven, Department of Chemistry, Senior post-doctoral researcher for Center of Excellence - Sep. 2002 - Aug. 2004
KU Leuven, Department of Chemistry, post-doctoral research fellow
Educational Background
■Research activity information
Papers
- Cellular Responses to Photothermal Therapy: Heat-Induced ERK Signaling and Intercellular Communication in Solid Tumors
Farsai Taemaitree, Yuta Takano, Daisuke Yamaguchi, Kazushi Yamaguchi, Yudai Yamashita, Motosuke Tsutsumi, Chentao Wen, Kohei Otomo, Kenji Hirai, James Hutchison, Indra Van Zundert, Sandra Krzyzowska, Maria Bravo, Sayuki Hirano, Koutarou D Kimura, Kazuhiro Aoki, Susana Rocha, Tomomi Nemoto, Beatrice Fortuni, Hiroshi Uji-i
Cold Spring Harbor Laboratory, 03 Mar. 2025
Abstract
Nanoparticle-mediated photothermal therapy (PTT) shows promise as a standalone cancer treatment but faces clinical challenges due to inconsistent efficacy. Its translation is further hindered by a limited understanding of plasmon-induced heat effects, such as stress responses and intercellular signaling. Here, we investigate how plasmon-induced local heating affects cellular behavior and fate within tumor spheroids by focusing on the activity of the extracellular signal-regulated kinase (ERK). Spheroids were prepared from HeLa cells that express a FRET-based ERK sensor, and ERK activity changes under photothermal stimuli were tracked using a deep-learning program, 3DeeCellTracker. Gold nanostars were used as highly efficient photothermal transducers. Our results revealed significant alterations in ERK signaling patterns upon photothermal stimulation compared to spontaneous ERK activity in untreated spheroids, including changes in the activation frequency, timing, and duration. Notably, photothermal-induced ERK activity propagated across neighboring cells within the spheroid, suggesting intercellular communication. Furthermore, analysis of cell death and division further demonstrated that laser power modulates cellular fate during photothermal therapy. This study provides insights for predicting the therapeutic effects of PPT and guides the rational design of next-generation photothermal strategies. Additionally, our approach demonstrates the potential of FRET-based biosensors and deep-learning tools as powerful methods to study the effects of various therapeutic stimuli on solid tumors at the single-cell level. - Optical Cavity Enhancement of Visible Light-Driven Photochemical Reaction in the Crystalline State
Ikuto Sasaki, Kiyonori Takahashi, Farsai Taemaitree, Takayoshi Nakamura, James Andell Hutchison, Hiroshi Uji-i, Kenji Hirai
Chemical Communications, Royal Society of Chemistry (RSC), 2025
Scientific journal, Photochemical reactions enable the synthesis of energetically unfavorable compounds but often require irradiation with ultraviolet light, which potentially induces side reactions. Here, cavity strong coupling enhances the efficiency of an... - Spatially Heterogeneous Dynamics of droplets formed by arginine-rich dipeptides and poly-A RNA during liquid-liquid phase separation
Ya Tian, Qiang Zhang, Kenji Hirai, Han Wen, Guilin Feng, Jiangtao Li, Farsai Taemaitree, Tomoko Inose, Kohsuke Kanekura, Hiroshi, Uji-i
Molecular Crystals and Liquid Crystals, May 2024, [Peer-reviewed], [Invited], ［Internationally co-authored］, [International Magazine]
English, Scientific journal - Optical Cavity Design and Functionality for Molecular Strong Coupling
Kenji Hirai, James A. Hutchison, Hiroshi Uji-i
Chemistry - A European Journal, Wiley, Nov. 2023, [Peer-reviewed], [Invited], ［Internationally co-authored］, [International Magazine]
English, Scientific journal, Optical cavity/molecule strong coupling offers attractive opportunities to modulate photochemical or photophysical processes. When atoms or molecules are placed in an optical cavity, they can coherently exchange photonic energy with optical cavity vacuum fields, entering the strong coupling interaction regime. Recent work suggests that the thermodynamic and kinetic properties of molecules can be significantly changed by strong coupling, resulting in the emergence of intriguing photochemical and photophysical phenomena. As more and more physico‐chemical systems are studied under strong coupling conditions, optical cavities have also advanced in their sophistication, responsiveness, and (multi)functionality. In this review, we highlight some of these recent developments, particularly focusing on Fabry‐Perot microcavities. - Remote Excitation of Tip-Enhanced Photoluminescence with a Parallel AgNW Coupler
Wannes Peeters, Shuichi Toyouchi, Yasuhiko Fujita, Mathias Wolf, Beatrice Fortuni, Eduard Fron, Tomoko Inose, Johan Hofkens, Takahiko Endo, Yasumitsu Miyata, Hiroshi Uji-i
ACS Omega, 8, 41, 38386, 38393, American Chemical Society (ACS), 20 Sep. 2023
Scientific journal - Site-Specific Synthesis of Conductive Graphitic Nanomaterials on a NiFe Thin Film by Localized Laser Irradiation
Hideki Fujiwara, Seigo Daikokuya, Tatsuki Mirokuin, Kyohei Hayashi, Mizuki Matsuzaka, Yuri Ohashi, Christophe Pin, Hideo Kaiju, Kenji Hirai, Hiroshi Uji-i
ACS Applied Nano Materials, 6, 15, 13885, 13893, American Chemical Society (ACS), 22 Jul. 2023
Scientific journal - Molecular Chemistry in Cavity Strong Coupling
Kenji Hirai, James A. Hutchison, Hiroshi Uji-i
Chemical Reviews, 123, 13, 8099, 8126, American Chemical Society (ACS), Jun. 2023, [Peer-reviewed], [Invited], ［Internationally co-authored］, [International Magazine]
English, Scientific journal - SERS Endoscopy for Monitoring Intracellular Drug Dynamics
Beatrice Fortuni, Monica Ricci, Raffaele Vitale, Tomoko Inose, Qiang Zhang, James Andell Hutchison, Kenji Hirai, Yasuhiko Fujita, Shuichi Toyouchi, Sandra Krzyzowska, Indra Van Zunder, Susana Rocha, Hiroshi Uji-i
ACS Sensors, 8, 6, 2340, 2347, American Chemical Society (ACS), 23 May 2023, [Peer-reviewed], ［Internationally co-authored］, [International Magazine]
English, Scientific journal - Light-mediated Covalently Patterned Graphene Substrate for Graphene-Enhanced Raman Scattering (GERS)
Guilin Feng, Nozomu Suzuki, Qiang Zhang, Jiangrao Li, Tomoko Inose, Farsai Taemaitree, Muhammed Shameem K M, Shuichi Toyouchi, Yasuhiko Fujita, Kenji Hirai, Hiroshi Uji-i
Chemical Communications, Royal Society of Chemistry (RSC), 2023
Scientific journal, We report covalently patterned graphene with acetic acid as a new potential candidate for graphene-enhanced Raman scattering (GERS). Rhodamine 6G molecule in direct contact with the covalently modified region shows... - Liquid-Phase Photo-induced Covalent Modification (PICM) of Single-Layer Graphene by Short-Chain Fatty Acids
Guilin Feng, Tomoko Inose, Nozomu Suzuki, Han Wen, Farsai Taemaitree, Mathias Wolf, Shuichi Toyouchi, Yasuhiko Fujita, Kenji Hirai, Hiroshi Uji-i
Nanoscale, 15, 10, 4932, 4939, Royal Society of Chemistry (RSC), 2023
Scientific journal, We report an efficient photo-induced covalent modification (PICM) of graphene by short-chain fatty acids (SCFAs) with an alkyl chain at the liquid-solid interface for spatially resolved chemical functionalization of graphene.... - Length-Controllable Gold-Coated Silver Nanowire Probes for High AFM-TERS Scattering Activity
Han Wen, Jiangtao Li, Qiang Zhang, Tomoko Inose, Wannes Peeters, Beatrice Fortuni, Hitoshi Asakawa, Akito Masuhara, Kenji Hirai, Shuichi Toyouchi, Yasuhiko Fujita, Hiroshi Uji-i
Nano Letters, American Chemical Society (ACS), 09 Dec. 2022
Scientific journal - A facile reprecipitation method of Quantum-confined CsPbBr3 perovskite quantum dots for narrow-band deep-blue emission
Naoaki Oshita, Kazuki Umemoto, Ryota Sato, Taisei Kimura, Takayuki Chiba, Satoshi Asakura, Hiroshi Uji-i, Akito Masuhara
Applied Physics Express, 15, 6, 065002, 065002, IOP Publishing, 01 Jun. 2022
Scientific journal, Abstract
Quantum-confined cesium lead tribromide perovskite quantum dots (PeQDs) are attractive photonic sources for versatile optoelectronic devices and thus the synthetic routes have been explored via various techniques. However, the lack of a general method to fabricate the quantum-confined PeQD with remarkable stability at colloidal state has been one of the major obstacles to device applications. Herein, we propose a simple and robust ligand-assisted reprecipitation method associated with didodecyl dimethyl ammonium bromide for quantum-confined PeQDs with remarkable stability at colloidal state. This method will shed a light on the field of colloidal PeQDs synthesis for the next generation of photonic sources. - Autotuning of Vibrational Strong Coupling for Site-Selective Reactions.
Kenji Hirai, Hiroto Ishikawa, Yasufumi Takahashi, James Andell Hutchison, Hiroshi Uji-I
Chemistry (Weinheim an der Bergstrasse, Germany), 28, 47, e202201260, 30 May 2022, [International Magazine]
English, Scientific journal, Site-selective chemistry opens new paths for the synthesis of technologically important molecules. When a reactant is placed inside a Fabry-Perot (FP) cavity, energy exchange between molecular vibrations and resonant cavity photons results in vibrational strong coupling (VSC). VSC has recently been implicated in modified chemical reactivity at specific reactive sites. However, as a reaction proceeds inside an FP cavity, the refractive index of the reaction solution changes, detuning the cavity mode away from the vibrational mode and weakening the VSC effect. Here we overcome this issue, developing actuatable FP cavities to allow automated tuning of cavity mode energy to maintain maximized VSC during a reaction. As an example, the site-selective reaction of the aldehyde over the ketone in 4-acetylbenzaldehyde is achieved by automated cavity tuning to maintain optimal VSC of the ketone carbonyl stretch during the reaction. A nearly 50% improvement in site-selective reactivity is observed compared to an FP cavity with static mirrors, demonstrating the utility of actuatable FP cavities as microreactors for organic chemistry. - All-Optical and One-Color Rewritable Chemical Patterning on Pristine Graphene under Water
Shuichi Toyouchi, Mathias Wolf, Guilin Feng, Yasuhiko Fujita, Beatrice Fortuni, Tomoko Inose, Kenji Hirai, Steven De Feyter, Hiroshi Uji-i
The Journal of Physical Chemistry Letters, 13, 17, 3796, 3803, American Chemical Society (ACS), 22 Apr. 2022
Scientific journal - Gold-coated silver nanowires for long lifetime AFM-TERS probes
Han Wen, Tomoko Inose, Kenji Hirai, Taiki Akashi, Shoji Sugioka, Jiangtao Li, Wannes Peeters, Eduard Fron, Beatrice Fortuni, Yoshihiko Nakata, Susana Rocha, Shuichi Toyouchi, Yasuhiko Fujita, Hiroshi Uji-i
NANOSCALE, 14, 14, 5439, 5446, Apr. 2022
English, Scientific journal - Host and guest joining forces: a holistic approach for metal-organic frameworks in nonlinear optics
Mathias Wolf, Kenji Hirai, Shuichi Toyouchi, Brent Daelemans, Eduard Fron, Hiroshi Uji-i
Journal of Materials Chemistry C, 10, 25, 9471, 9477, Royal Society of Chemistry (RSC), 2022
Scientific journal, Metal-organic frameworks (MOFs) are an interesting candidate for applications in nonlinear optics (NLO). However, current design strategies for MOFs in NLO are typically limited to either engineering the MOF itself... - Versatile and Robust Method for Antibody Conjugation to Nanoparticles with High Targeting Efficiency
Indra Van Zundert, Maria Bravo, Olivier Deschaume, Pierre Cybulski, Carmen Bartic, Johan Hofkens, Hiroshi Uji-i, Beatrice Fortuni, Susana Rocha
PHARMACEUTICS, 13, 12, Dec. 2021
English, Scientific journal - Li@C-60 thin films: characterization and nonlinear optical properties
Mathias Wolf, Shuichi Toyouchi, Peter Walke, Kazuki Umemoto, Akito Masuhara, Hiroshi Fukumura, Yuta Takano, Michio Yamada, Kenji Hirai, Eduard Fron, Hiroshi Uji-i
RSC ADVANCES, 12, 1, 389, 394, Dec. 2021
English, Scientific journal - Failure-Experiment-Supported Optimization of Poorly Reproducible Synthetic Conditions for Novel Lanthanide Metal-Organic Frameworks with Two-Dimensional Secondary Building Units
Yu Kitamura, Emi Terado, Zechen Zhang, Hirofumi Yoshikawa, Tomoko Inose, Hiroshi Uji-i, Masaharu Tanimizu, Akihiro Inokuchi, Yoshinobu Kamakura, Daisuke Tanaka
CHEMISTRY-A EUROPEAN JOURNAL, 27, 66, 16274, 16274, Nov. 2021
English - Failure-Experiment-Supported Optimization of Poorly Reproducible Synthetic Conditions for Novel Lanthanide Metal-Organic Frameworks with Two-Dimensional Secondary Building Units
Yu Kitamura, Emi Terado, Zechen Zhang, Hirofumi Yoshikawa, Tomoko Inose, Hiroshi Uji-i, Masaharu Tanimizu, Akihiro Inokuchi, Yoshinobu Kamakura, Daisuke Tanaka
CHEMISTRY-A EUROPEAN JOURNAL, 27, 66, 16347, 16353, Nov. 2021
English, Scientific journal - Gold-Photodeposited Silver Nanowire Endoscopy for Cytosolic and Nuclear pH Sensing
Qiang Zhang, Tomoko Inose, Monica Ricci, Jiangtao Li, Ya Tian, Han Wen, Shuichi Toyouchi, Eduard Fron, Anh Thi Ngoc Dao, Hitoshi Kasai, Susana Rocha, Kenji Hirai, Beatrice Fortuni, Hiroshi Uji-i
ACS Applied Nano Materials, 4, 9, 9886, 9894, 07 Sep. 2021
English, Scientific journal - Controlling polymorphism of metal-organic frameworks
Kenji Hirai, Atsushi Nagahashi, Taisei Kitagawa, Hiroshi Uji-i
Metamaterials, Metadevices, and Metasystems 2021, SPIE, 01 Aug. 2021
International conference proceedings - Gold-Etched Silver Nanowire Endoscopy: Toward a Widely Accessible Platform for Surface-Enhanced Raman Scattering-Based Analysis in Living Cells
Monica Ricci, Beatrice Fortuni, Raffaele Vitale, Qiang Zhang, Yasuhiko Fujita, Shuichi Toyouchi, Gang Lu, Susana Rocha, Tomoko Inose, Hiroshi Uji-i
Analytical Chemistry, 93, 12, 5037, 5045, 30 Mar. 2021
English, Scientific journal - Polariton Chemistry in Cavity Vacuum Fields
Kenji Hirai, Hiroshi Uji-i
Chemistry Letters, 50, 4, 727, 732, 13 Jan. 2021
English, Scientific journal - Adaptive Optical Two-Photon Microscopy for Surface-Profiled Living Biological Specimens.
Kazushi Yamaguchi, Kohei Otomo, Yuichi Kozawa, Motosuke Tsutsumi, Tomoko Inose, Kenji Hirai, Shunichi Sato, Tomomi Nemoto, Hiroshi Uji-I
ACS omega, 6, 1, 438, 447, 12 Jan. 2021, [International Magazine]
English, Scientific journal - Selective Crystallization via Vibrational Strong Coupling
Kenji Hirai, Hiroto Ishikawa, Thibault Chervy, James Andell Hutchison, Hiroshi Uji-i
Chemical Science, 12, 36, 11986, 11994, 2021
English, Scientific journal - Electrolytic synthesis of porphyrinic Zr-metal–organic frameworks with selective crystal topologies
Keito Okada, Yoko Tanaka, Tomoko Inose, Hiroshi Ujii, Hirofumi Yoshikawa, Daisuke Tanaka
Dalton Transactions, 50, 16, 5411, 5415, Royal Society of Chemistry (RSC), 2021
Scientific journal,The thermodynamic (PCN-222) and kinetic (PCN-224) products of porphyrinic Zr-metal–organic frameworks (MOFs) were synthesized
via an anodic dissolution approach for the first time. - Simple Production of Highly Luminescent Organometal Halide Perovskite Nanocrystals Using Ultrasound-Assisted Bead Milling
Kazuki Umemoto, Hinako Ebe, Ryota Sato, Junya Enomoto, Naoaki Oshita, Taisei Kimura, Tomoko Inose, Takahiro Nakamura, Takayuki Chiba, Satoshi Asakura, Hiroshi Uji-i, Akito Masuhara
ACS Sustainable Chemistry & Engineering, 8, 44, 16469, 16476, 09 Nov. 2020
English, Scientific journal - FRET-based intracellular investigation of nanoprodrugs toward highly efficient anticancer drug delivery (vol 12, pg 16710, 2020)
Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Tomoko Inose, Hitoshi Kasai
NANOSCALE, 12, 42, 21951, 21951, Nov. 2020
English - Spatially and Temporally Resolved Heterogeneities in a Miscible Polymer Blend
Guofeng Zhang, Susana Rocha, Gang Lu, Haifeng Yuan, Hiroshi Uji-i, George A. Floudas, Klaus Muellen, Liantuan Xiao, Johan Hofkens, Elke Debroye
ACS OMEGA, 5, 37, 23931, 23939, Sep. 2020
English, Scientific journal - Recent Progress of Vibropolaritonic Chemistry
Kenji Hirai, James A Hutchison, Hiroshi Uji-i
ChemPlusChem, 85, 9, 1981, 1988, 03 Aug. 2020, [Peer-reviewed]
English, Scientific journal - Low-Cytotoxic Gold-Coated Silver Nanoflowers for Intracellular pH Sensing
Qiang Zhang, Han Wen, Kiri Watanabe, Ibuki Kotani, Monica Ricci, Beatrice Fortuni, Anh Thi Ngoc Dao, Akito Masuhara, Kenji Hirai, Hitoshi Kasai, Tomoko Inose, Hiroshi Uji-i
ACS Applied Nano Materials, 3, 8, 7643, 7650, 09 Jul. 2020, [Peer-reviewed]
English, Scientific journal - Pseudo‐membrane jackets: Two‐dimensional coordination polymers achieving visible phase separation in cell membrane
Ryo Ohtani, Kenichi Kawano, Masanao Kinoshita, Saeko Yanaka, Hikaru Watanabe, Kenji Hirai, Shiroh Futaki, Nobuaki Matsumori, Hiroshi Uji-i, Masaaki Ohba, Koichi Kato, Shinya Hayami
Angewandte Chemie International Edition, 59, 41, 17931, 17937, 30 Jun. 2020, [Peer-reviewed]
English, Scientific journal - Synthesis of highly luminescent CH3NH3PbBr3 perovskite nanocrystals via a forced thin film reactor
Masaki Takeda, Masaaki Yokoyama, Kazuki Umemoto, Bozhang Lyu, Yoshihito Takahashi, Sasiphapa Rodbuntum, Junya Enomoto, Keitaro Tozawa, Tomohiro Nohara, Keisuke Tabata, Ryota Sato, Takayuki Chiba, Satoshi Asakura, Hiroshi Uji-i, Akito Masuhara
JAPANESE JOURNAL OF APPLIED PHYSICS, 59, Jun. 2020, [Peer-reviewed]
English, Scientific journal - Two-Photon-Induced [2+2] Cycloaddition of Bis-thymines: A Biocompatible and Reversible Approach
Monica Ricci, Martin G. T. A. Rutten, Shuichi Toyouchi, Sepa Nanayakkara, Beatrice Fortuni, Raffaele Vitale, Susana Rocha, Daniela A. Wilson, Johan Hofkens, Kei Saito, Hiroshi Uji-I
ACS OMEGA, 5, 20, 11547, 11552, May 2020
English, Scientific journal - Photo-induced electrodeposition of metallic nanostructures on graphene
Kangwei Xia, Wei-Yi Chiang, Cesar Javier Lockhart de la Rosa, Yasuhiko Fujita, Shuichi Toyouchi, Haifeng Yuan, Jia Su, Hiroshi Masuhara, Stefan De Gendt, Steven De Feyter, Johan Hofkens, Hiroshi Uji-i
NANOSCALE, 12, 20, 11063, 11069, May 2020
English, Scientific journal - Controlled Fabrication of Optical Signal Input/Output Sites on Plasmonic Nanowires
Shuichi Toyouchi, Mathias Wolf, Yusuke Nakao, Yasuhiko Fujita, Tomoko Inose, Beatrice Fortuni, Kenji Hirai, Johan Hofkens, Steven De Feyter, James Hutchison, Hiroshi Uji-i
Nano Letters, 20, 4, 2460, 2467, 10 Mar. 2020, [Peer-reviewed]
English, Scientific journal - Effects of alkylamine chain length on perovskite nanocrystals after washing and perovskite light-emitting diodes
Yuki Tezuka, Kazuki Umemoto, Masaki Takeda, Yoshihito Takahashi, Hinako Ebe, Junya Enomoto, Sasiphapa Rodbuntum, Tomohiro Nohara, Daniela Fontecha, Satoshi Asakura, Takayuki Chiba, Madalina Ioana Furis, Tsukasa Yoshida, Hiroshi Uji-i, Akito Masuhara
JAPANESE JOURNAL OF APPLIED PHYSICS, 59, SDDC04-1, SDDC04-5, Mar. 2020, [Peer-reviewed]
English, Scientific journal - Modulation of Prins Cyclization by Vibrational Strong Coupling.
Kenji Hirai, Rie Takeda, James A Hutchison, Hiroshi Uji-I
Angewandte Chemie (International ed. in English), 59, 13, 5332, 5335, 22 Jan. 2020, [Peer-reviewed], [International Magazine]
English, Scientific journal - Label-free visualization of heterogeneities and defects in metal–organic frameworks using nonlinear optics
Mathias Wolf, Kenji Hirai, Shuichi Toyouchi, Eduard Fron, Wannes Peeters, Steven De Feyter, Hiroshi Uji-i
Chemical Communications, 56, 87, 13331, 13334, 2020
English, Scientific journal - Plasmon-Associated Control of Chemical Reaction at Nanometer Scale
Shuichi Toyouchi, Tomoko Inose, Kenji Hirai, Hiroshi Uji-i
Photosynergetic Responses in Molecules and Molecular Aggregates, 117, 133, Springer Singapore, 2020
In book - FRET-based intracellular investigation of nanoprodrugs toward highly efficient anticancer drug delivery
Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Tomoko Inose, Hitoshi Kasai
Nanoscale, 12, 32, 16710, 16715, 2020
English, Scientific journal - Multicolour photochromic fluorescence of a fluorophore encapsulated in a metal–organic framework
Kenji Hirai, Taisei Kitagawa, Hideki Fujiwara, Jenny Pirillo, Yuh Hijikata, Tomoko Inose, Hiroshi Uji-i
Chemical Communications, 56, 67, 9651, 9654, 2020, [Peer-reviewed]
English, Scientific journal - On the Thermal Stability of Aryl Groups Chemisorbed on Graphite
Hans Van Gorp, Peter Walke, Joan Teyssandier, Brandon E. Hirsch, Hiroshi Uji-i, Kazukuni Tahara, Yoshito Tobe, Mark Van der Auweraer, Steven De Feyter
JOURNAL OF PHYSICAL CHEMISTRY C, 124, 3, 1980, 1990, Jan. 2020, [Peer-reviewed]
English, Scientific journal - One-Step Covalent Immobilization of beta-Cyclodextrin on sp(2) Carbon Surfaces for Selective Trace Amount Probing of Guests
Zhi Li, Joachim F. R. Van Guyse, Victor R. de la Rosa, Hans Van Gorp, Peter Walke, Miriam C. Rodriguez Gonzalez, Hiroshi Uji-i, Richard Hoogenboom, Steven De Feyter, Stijn F. L. Mertens
ADVANCED FUNCTIONAL MATERIALS, 29, 36, Sep. 2019
English, Scientific journal - Water-mediated polyol synthesis of pencil-like sharp silver nanowires suitable for nonlinear plasmonics.
Inose T, Toyouchi S, Lu G, Umemoto K, Tezuka Y, Lyu B, Masuhara A, Fron E, Fujita Y, Hirai K, Uji-I H
Chemical communications (Cambridge, England), 55, 77, 11630, 11633, Sep. 2019, [Peer-reviewed]
English, Scientific journal - Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening
Matteo Boretto, Nina Maenhoudt, Xinlong Luo, Aurelie Hennes, Bram Boeckx, Bich Bui, Ruben Heremans, Lisa Perneell, Hiroto Kobayashi, Indra Van Zundert, Hilde Brems, Benoit Cox, Marc Ferrante, Hiroshi Uji-i, Kian Peng Koh, Thomas D'Hooghe, Arne Vanhie, Ignace Vergote, Christel Meuleman, Carla Tomassetti, Diether Lambrechts, Joris Vriens, Dirk Timmerman, Hugo Vankelecom
NATURE CELL BIOLOGY, 21, 8, 1041, +, Aug. 2019
English, Scientific journal - Graphite and Graphene Fairy Circles: A Bottom-Up Approach for the Formation of Nanocorrals
Thanh Hai Phan, Hans Van Gorp, Zhi Li, Thi Mien Trung Huynh, Yasuhiko Fujita, Lander Verstraete, Samuel Eyley, Wim Thielemans, Hiroshi Uji-i, Brandon E. Hirsch, Stijn F. L. Mertens, John Greenwood, Oleksandr Ivasenko, Steven De Feyter
ACS NANO, 13, 5, 5559, 5571, May 2019
English, Scientific journal - Synthesis of 42-faceted bismuth vanadate microcrystals for enhanced photocatalytic activity
Xueting Zhai, Zhuoyao Li, Zichen Lu, Guilin Wang, Ping Li, Yongqian Gao, Xiao Huang, Wei Huang, Hiroshi Uji-i, Gang Lu
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 542, 207, 212, Apr. 2019
English, Scientific journal - PSF Distortion in Dye-Plasmonic Nanomaterial Interactions: Friend or Foe?
Rashad Baiyasi, Seyyed Ali Hosseini Jebeli, Qingfeng Zhang, Liang Su, Johan Hofkens, Hiroshi Uji-i, Stephan Link, Christy F. Landes
ACS PHOTONICS, 6, 3, 699, 708, Mar. 2019
English, Scientific journal - Graphene Meets Ionic Liquids: Fermi Level Engineering via Electrostatic Forces
Gangamallaiah Velpula, Roald Phillipson, Jian Xiang Lian, David Cornil, Peter Walke, Ken Verguts, Steven Brems, Hiroshi Uji-i, Stefan De Gendt, David Beljonne, Roberto Lazzaroni, Kunal S. Mali, Steven De Feyter
ACS NANO, 13, 3, 3512, 3521, Mar. 2019
English, Scientific journal - Organoids from pituitary as a novel research model toward pituitary stem cell exploration
Benoit Cox, Emma Laporte, Annelies Vennekens, Hiroto Kobayashi, Charlotte Nys, Indra Van Zundert, Hiroshi Uji-i, Alithe Vercauteren Drubbel, Benjamin Beck, Heleen Roose, Matteo Boretto, Hugo Vankelecom
JOURNAL OF ENDOCRINOLOGY, 240, 2, 287, 308, Feb. 2019
English, Scientific journal - Plasmonic waveguiding spectroscopy and microscopy
Shuichi Toyouchi, Tomoko Inose, Yasuhiko Fujita, Hiroshi Uji-i
2019 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO), 2019
English, International conference proceedings - Polymeric Engineering of Nanoparticles for Highly Efficient Multifunctional Drug Delivery Systems
B. Fortuni, T. Inose, M. Ricci, Y. Fujita, I. van Zundert, A. Masuhara, E. Fron, H. Mizuno, L. Latterini, S. Rocha, H. Uji-i
Scientific Reports, 9, Jan. 2019, [Peer-reviewed]
English, Scientific journal - Separation of mono-dispersed CH3NH3PbBr3 perovskite quantum dots via dissolution of nanocrystals
Kazuki Umemoto, Masaki Takeda, Yuki Tezuka, Takayuki Chiba, Matthew Schuette White, Tomoko Inose, Tsukasa Yoshida, Satoshi Asakura, Shuichi Toyouchi, Hiroshi Uji-i, Akito Masuhara
CRYSTENGCOMM, 20, 44, 7053, 7057, Nov. 2018
English, Scientific journal - Facilitating Tip-Enhanced Raman Scattering on Dielectric Substrates via Electrical Cutting of Silver Nanowire Probes
Hiroshi Uji-i
The Journal of Physical Chemistry Letters, 9, 24, 7117, 7122, Nov. 2018, [Peer-reviewed]
English, Scientific journal - Mapping Transient Protein Interactions at the Nanoscale in Living Mammalian Cells
Herlinde De Keersmaecker, Rafael Camacho, David Manuel Rantasa, Eduard Fron, Hiroshi Uji-i, Hideaki Mizuno, Susana Rocha
ACS NANO, 12, 10, 9842, 9854, Oct. 2018
English, Scientific journal - Silver nanowires for highly reproducible cantilever based AFM-TERS microscopy: Towards a universal TERS probe
Peter Walke, Yasuhiko Fujita, Wannes Peeters, Shuichi Toyouchi, Wout Frederickx, Steven De Feyter, Hiroshi Uji-I
Nanoscale, 10, 16, 7556, 7565, 28 Apr. 2018, [Peer-reviewed]
English, Scientific journal - Orthogonal Probing of Single-Molecule Heterogeneity by Correlative Fluorescence and Force Microscopy
Wout Frederickx, Susana Rocha, Yasuhiko Fujita, Koen Kennes, Herlinde De Keersmaecker, Steven De Feyter, Hiroshi Uji-I, Willem Vanderlinden
ACS Nano, 12, 1, 168, 177, 23 Jan. 2018, [Peer-reviewed]
English, Scientific journal - One-Directional Antenna Systems: Energy Transfer from Monomers to J-Aggregates within 1D Nanoporous Aluminophosphates
Rebeca Sola-Llano, Yasuhiko Fujita, Luis Gómez-Hortigüela, Almudena Alfayate, Hiroshi Uji-I, Eduard Fron, Shuichi Toyouchi, Joaquín Pérez-Pariente, Iñigo López-Arbeloa, Virginia Martínez-Martínez
ACS Photonics, 5, 1, 151, 157, 17 Jan. 2018, [Peer-reviewed]
English, Scientific journal - Correlative atomic force and single-molecule fluorescence microscopy of nucleoprotein complexes
Herlinde De Keersmaecker, Wout Frederickx, Yasuhiko Fujita, Steven De Feyter, Hiroshi Uji-i, Susana Rocha, Willem Vanderlinden
Methods in Molecular Biology, 1814, 339, 359, Humana Press Inc., 2018
English, In book - Size control of CH3NH3PbBr3 perovskite cuboid fine crystals synthesized by ligand-free reprecipitation method
Kazuki Umemoto, Yong-Jin Pu, Cigdem Yumusak, Markus Clark Scharber, Matthew Schuette White, Niyazi Serdar Sariciftci, Tsukasa Yoshida, Jun Matsui, Hiroshi Uji-i, Akito Masuhara
Microsystem Technologies, 24, 1, 619, 623, 01 Jan. 2018, [Peer-reviewed]
English, Scientific journal - Remote plasmonic optical trapping on silver nanowire induced by nonlinear wave-mixing effects
Shuichi Toyouchi, Mathias Wolf, Yasuhiko Fujita, Hiroshi Uji-I
Proceedings of SPIE - The International Society for Optical Engineering, 10712, 2018, [Peer-reviewed]
English, International conference proceedings - Curve computation by geodesics and graph modelling for polymer analysis
Somia Rahmoun, Fabrice Mairesse, Hiroshi Uji-i, Johan Hofkens, Tadeusz Sliwa
SIGNAL IMAGE AND VIDEO PROCESSING, 11, 8, 1469, 1476, Nov. 2017, [Peer-reviewed]
English, Scientific journal - In situ synthesis of Au-shelled Ag nanoparticles on PDMS for flexible, long-life, and broad spectrum-sensitive SERS substrates
B. Fortuni, T. Inose, S. Uezono, S. Toyouchi, K. Umemoto, S. Sekine, Y. Fujita, M. Ricci, G. Lu, A. Masuhara, J. A. Hutchison, L. Latterini, H. Uji-i
CHEMICAL COMMUNICATIONS, 53, 82, 11298, 11301, Oct. 2017, [Peer-reviewed]
English, Scientific journal - Highly controllable direct femtosecond laser writing of gold nanostructures on titanium dioxide surfaces
Y. Fujita, R. Aubert, P. Walke, H. Yuan, B. Kenens, T. Inose, C. Steuwe, S. Toyouchi, B. Fortuni, M. Chamtouri, K. P. F. Janssen, S. De Feyter, M. B. J. Roeffaers, H. Uji-i
NANOSCALE, 9, 35, 13025, 13033, Sep. 2017, [Peer-reviewed]
English, Scientific journal - Facet-Dependent Diol-Induced Density of States of Anatase TiO2 Crystal Surface
Maha Chamtouri, Bart Kenens, Remko Aubert, Gang Lu, Tomoko Inose, Yasuhiko Fujita, Akito Masuhara, Johan Hofkens, Hiroshi Uji-I
ACS Omega, 2, 7, 4032, 4038, 31 Jul. 2017, [Peer-reviewed]
English, Scientific journal - Plasmon-Mediated Surface Engineering of Silver Nanowires for Surface-Enhanced Raman Scattering
Gang Lu, Haifeng Yuan, Liang Su, Bart Kenens, Yasuhiko Fujita, Maha Chamtouri, Maria Pszona, Eduard Fron, Jacek Waluk, Johan Hofkens, Hiroshi Uji-i
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 8, 13, 2774, 2779, Jul. 2017, [Peer-reviewed]
English, Scientific journal - A novel method for in situ synthesis of SERS-active gold nanostars on polydimethylsiloxane film
B. Fortuni, Y. Fujita, M. Ricci, T. Inose, R. Aubert, G. Lu, J. A. Hutchison, J. Hofkens, L. Latterini, H. Uji-i
CHEMICAL COMMUNICATIONS, 53, 37, 5121, 5124, May 2017, [Peer-reviewed]
English, Scientific journal - Area-selective passivation of sp(2) carbon surfaces by supramolecular self-assembly
Zhi Li, Hans Van Gorp, Peter Walke, Thanh Hai Phan, Yasuhiko Fujita, John Greenwood, Oleksandr Ivasenko, Kazukuni Tahara, Yoshito Tobe, Hiroshi Uji-, Stijn F. L. Mertens, Steven De Feyter
NANOSCALE, 9, 16, 5188, 5193, Apr. 2017, [Peer-reviewed]
English, Scientific journal - Surface density-of-states engineering of anatase TiO2 by small polyols for enhanced visible-light photocurrent generation
Remko Aubert, Bart Kenens, Maha Chamtouri, Yasuhiko Fujita, Beatrice Fortuni, Gang Lu, James A. Hutchison, Tomoko Inose, Hiroshi Uji-I
ACS Omega, 2, 10, 6309, 6313, 2017, [Peer-reviewed]
English, Scientific journal - Tunable doping of graphene by using physisorbed self-assembled networks
Roald Phillipson, Cesar J. Lockhart de la Rosa, Joan Teyssandier, Peter Walke, Deepali Waghray, Yasuhiko Fujita, Jinne Adisoejoso, Kunal S. Mali, Inge Asselierghs, Cedric Huyghebaert, Hiroshi Uji-i, Stefan De Gendt, Steven De Feyter
NANOSCALE, 8, 48, 20017, 20026, Dec. 2016, [Peer-reviewed]
English, Scientific journal - Formation of a Nonlinear Optical Host-Guest Hybrid Material by Tight Confinement of LDS722 into Aluminophosphate 1D Nanochannels
Rebeca Sola-Llano, Virginia Martinez-Martinez, Yasuhiko Fujita, Luis Gomez-Hortigueela, Almudena Alfayate, Hiroshi Uji-i, Eduard Fron, Joaquin Perez-Pariente, Inigo Lopez-Arbeloa
CHEMISTRY-A EUROPEAN JOURNAL, 22, 44, 15700, 15711, Oct. 2016, [Peer-reviewed]
English, Scientific journal - Remote excitation-tip-enhanced Raman scattering microscopy using silver nanowire
Yasuhiko Fujita, Peter Walke, Steven De Feyter, Hiroshi Uji-i
JAPANESE JOURNAL OF APPLIED PHYSICS, 55, 8, Aug. 2016, [Peer-reviewed]
English, Scientific journal - Tip-enhanced Raman scattering microscopy: Recent advance in tip production
Yasuhiko Fujita, Peter Walke, Steven De Feyter, Hiroshi Uji-i
JAPANESE JOURNAL OF APPLIED PHYSICS, 55, 8, Aug. 2016, [Peer-reviewed]
English - Mechano- and Photochromism from Bulk to Nanoscale: Data Storage on Individual Self-Assembled Ribbons
Damiano Genovese, Alessandro Aliprandi, Eko A. Prasetyanto, Matteo Mauro, Michael Hirtz, Harald Fuchs, Yasuhiko Fujita, Hiroshi Uji-, Sergei Lebedkin, Manfred Kappes, Luisa De Cola
ADVANCED FUNCTIONAL MATERIALS, 26, 29, 5271, 5278, Aug. 2016, [Peer-reviewed]
English, Scientific journal - Biocompatible Label-Free Detection of Carbon Black Particles by Femtosecond Pulsed Laser Microscopy
Hannelore Bove, Christian Steuwe, Eduard Fron, Eli Slenders, Jan D'Haen, Yasuhiko Fujita, Hiroshi Uji-i, Martin vandeVen, Maarten Roeffaers, Marcel Ameloot
NANO LETTERS, 16, 5, 3173, 3178, May 2016, [Peer-reviewed]
English, Scientific journal - Surface Plasmon-Assisted Site-Specific Cutting of Silver Nanowires Using Femtosecond Laser
Yasuhiko Fujita, Peter Walke, Gang Lu, Maha Chamtouri, Steven De Feyter, Hiroshi Uji-i
ADVANCED MATERIALS TECHNOLOGIES, 1, 2, May 2016, [Peer-reviewed]
English, Scientific journal - Degradation of Methylammonium Lead Iodide Perovskite Structures through Light and Electron Beam Driven Ion Migration
Haifeng Yuan, Elke Debroye, Kris Janssen, Hiroyuki Naiki, Christian Steuwe, Gang Lu, Michele Moris, Emanuele Orgiu, Hiroshi Uji-i, Frans De Schryver, Paolo Samori, Johan Hofkens, Maarten Roeffaers
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 7, 3, 561, 566, Feb. 2016, [Peer-reviewed]
English, Scientific journal - Super-resolution Localization and Defocused Fluorescence Microscopy on Resonantly Coupled Single-Molecule, Single-Nanorod Hybrids
Liang Su, Haifeng Yuan, Gang Lu, Susana Rocha, Michel Orrit, Johan Hofkens, Hiroshi Uji-i
ACS NANO, 10, 2, 2455, 2466, Feb. 2016, [Peer-reviewed]
English, Scientific journal - Distribution, organization, and dynamics of EGF receptor in the plasma membrane studied by super-resolution imaging
Rocha, S., De Keersmaecker, H., Fron, E., Abe, M., Makino, A., Uji-i, H., Hofkens, J., Kobayashi, T., Miyawaki, A., Mizuno, H.
Food as Medicine: Functional Food Plants of Africa, Food as Medicine: Functional Food Plants of Africa, 2016
Scientific journal - Nanoscale Study of Polymer Dynamics
Masoumeh Keshavarz, Hans Engelkamp, Jialiang Xu, Els Braeken, Matthijs B. J. Otten, Hiroshi Uji-i, Erik Schwartz, Matthieu Koepf, Anja Vananroye, Jan Vermant, Roeland J. M. Nolte, Frans De Schryver, Jan C. Maan, Johan Hofkens, Peter C. M. Christianen, Alan E. Rowan
ACS NANO, 10, 1, 1434, 1441, Jan. 2016, [Peer-reviewed]
English, Scientific journal - Curve Extraction by Geodesics Fusion: Application to Polymer Reptation Analysis
Somia Rahmoun, Fabrice Mairesse, Hiroshi Uji-i, Johan Hofkens, Tadeusz Sliwa
IMAGE AND SIGNAL PROCESSING (ICISP 2016), 9680, 79, 88, 2016, [Peer-reviewed]
English, International conference proceedings - Solvent-induced improvement of Au photo-deposition and resulting photo-catalytic efficiency of Au/TiO2
Bart Kenens, Maha Chamtouri, Remko Aubert, Kana Miyakawa, Yasufumi Hayasaka, Hiroyuki Naiki, Hiroki Watanabe, Tomoko Inose, Yasuhiko Fujita, Gang Lu, Akito Masuhara, Hiroshi Uji-i
RSC ADVANCES, 6, 100, 97464, 97468, 2016, [Peer-reviewed]
English, Scientific journal - Field-controlled charge separation in a conductive matrix at the single-molecule level: Toward controlling single-molecule fluorescence intermittency
Koen Kennes, Peter Dedecker, James A. Hutchison, Eduard Fron, Hiroshi Uji-I, Johan Hofkens, Mark Van Der Auweraer
ACS Omega, 1, 6, 1383, 1392, 2016, [Peer-reviewed]
English, Scientific journal - Mechanism Behind the Apparent Large Stokes Shift in LSSmOrange Investigated by Time-Resolved Spectroscopy
Eduard Fron, Herlinde De Keersmaecker, Susana Rocha, Yannick Baeten, Gang Lu, Hiroshi Uji-, Mark Van der Auweraer, Johan Hofkens, Hideaki Mizuno
JOURNAL OF PHYSICAL CHEMISTRY B, 119, 47, 14880, 14891, Nov. 2015, [Peer-reviewed]
English, Scientific journal - Covalent Modification of Graphene and Graphite Using Diazonium Chemistry: Tunable Grafting and Nanomanipulation
John Greenwood, Thanh Hai Phan, Yasuhiko Fujita, Zhi Li, Oleksandr Lvasenko, Willem Vanderlinden, Hans Van Gorp, Wout Frederickx, Gang Lu, Kazukuni Tahara, Yoshito Tobe, Hiroshi Uji-i, Stijn F. L. Mertens, Steven De Feyter
ACS NANO, 9, 5, 5520, 5535, May 2015, [Peer-reviewed]
English, Scientific journal - Visualization of molecular fluorescence point spread functions via remote excitation switching fluorescence microscopy
Liang Su, Gang Lu, Bart Kenens, Susana Rocha, Eduard Fron, Haifeng Yuan, Chang Chen, Pol Van Dorpe, Maarten B. J. Roeffaers, Hideaki Mizuno, Johan Hofkens, James A. Hutchison, Hiroshi Uji-i
NATURE COMMUNICATIONS, 6, Feb. 2015, [Peer-reviewed]
English, Scientific journal - Reshaping anisotropic gold nanoparticles through oxidative etching: the role of the surfactant and nanoparticle surface curvature
Haifeng Yuan, Kris P. F. Janssen, Thomas Franklin, Gang Lu, Liang Su, Xian Gu, Hiroshi Uji-i, Maarten B. J. Roeffaers, Johan Hofkens
RSC ADVANCES, 5, 9, 6829, 6833, 2015, [Peer-reviewed]
English, Scientific journal - Au nanoparticle scaffolds modulating intermolecular interactions among the conjugated azobenzenes chemisorbed on curved surfaces: tuning the kinetics of cis-trans isomerisation
Corinna Raimondo, Bart Kenens, Federica Reinders, Marcel Mayor, Hiroshi Uji-i, Paolo Samori
NANOSCALE, 7, 33, 13836, 13839, 2015, [Peer-reviewed]
English, Scientific journal - Tip-Induced Chemical Manipulation of Metal Porphyrins at a Liquid/Solid Interface
Min Li, Duncan den Boer, Patrizia Iavicoli, Jinne Adisoejoso, Hiroshi Uji-i, Mark Van der Auweraer, David B. Amabilino, Johannes A. A. W. Elemans, Steven De Feyter
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136, 50, 17418, 17421, Dec. 2014, [Peer-reviewed]
English, Scientific journal - Rationalizing Inter- and Intracrystal Heterogeneities in Dealuminated Acid Mordenite Zeolites by Stimulated Raman Scattering Microscopy Correlated with Super-resolution Fluorescence Microscopy
Kuan-Lin Liu, Alexey V. Kubarev, Jordi Van Loon, Hiroshi Uji-i, Dirk E. De Vos, Johan Hofkens, Maarten B. J. Roeffaers
ACS NANO, 8, 12, 12650, 12659, Dec. 2014, [Peer-reviewed]
English, Scientific journal - A silver nanowire-based tip suitable for STM tip-enhanced Raman scattering
Yasuhiko Fujita, Rie Chiba, Gang Lu, Noriko N. Horimoto, Shinji Kajimoto, Hiroshi Fukumura, Hiroshi Uji-
CHEMICAL COMMUNICATIONS, 50, 69, 9839, 9841, Sep. 2014, [Peer-reviewed]
English, Scientific journal - Live-Cell SERS Endoscopy Using Plasmonic Nanowire Waveguides
Gang Lu, Herlinde De Keersmaecker, Liang Su, Bart Kenens, Susana Rocha, Eduard Fron, Chang Chen, Pol Van Dorpe, Hideaki Mizuno, Johan Hofkens, James A. Hutchison, Hiroshi Uji-i
ADVANCED MATERIALS, 26, 30, 5124, 5128, Aug. 2014, [Peer-reviewed]
English, Scientific journal - Shear-Stress-Induced Conformational Changes of von Willebrand Factor in a Water-Glycerol Mixture Observed with Single Molecule Microscopy
Robrecht M. A. Vergauwe, Hiroshi Uji-i, Karen De Ceunynck, Jan Vermant, Karen Vanhoorelbeke, Johan Hofkens
JOURNAL OF PHYSICAL CHEMISTRY B, 118, 21, 5660, 5669, May 2014, [Peer-reviewed]
English, Scientific journal - Membrane Remodeling Processes Induced by Phospholipase Action
Susana Rocha, Herlinde De Keersmaecker, James A. Hutchison, Karen Vanhoorelbeke, Johan A. Martens, Johan Hofkens, Hiroshi Uji-i
LANGMUIR, 30, 16, 4743, 4751, Apr. 2014, [Peer-reviewed]
English, Scientific journal - Single Particle Tracking of ADAMTS13 ( A Disintegrin and Metalloprotease with Thrombospondin Type-1 Repeats) Molecules on Endothelial von Willebrand Factor Strings
Karen De Ceunynck, Susana Rocha, Simon F. De Meyer, J. Evan Sadler, Hiroshi Uji-i, Hans Deckmyn, Johan Hofkens, Karen Vanhoorelbeke
JOURNAL OF BIOLOGICAL CHEMISTRY, 289, 13, 8903, 8915, Mar. 2014, [Peer-reviewed]
English, Scientific journal - A surface-bound molecule that undergoes optically biased Brownian rotation
James A. Hutchison, Hiroshi Uji-i, Ania Deres, Tom Vosch, Susana Rocha, Sibylle Mueller, Andreas A. Bastian, Joerg Enderlein, Hassan Nourouzi, Chen Li, Andreas Herrmann, Klaus Muellen, Frans De Schryver, Johan Hofkens
NATURE NANOTECHNOLOGY, 9, 2, 131, 136, Feb. 2014, [Peer-reviewed]
English, Scientific journal - Remote excitation fluorescence correlation spectroscopy using silver nanowires
Liang Su, Haifeng Yuan, Gang Lu, Johan Hofkens, Maarten Roeffaers, Hiroshi Uji-i
NANOPHOTONICS AND MICRO/NANO OPTICS II, 9277, 2014, [Peer-reviewed]
English, International conference proceedings - ADAMTS13 meets von Willebrand factor strings: a single molecule approach
De Ceunynck K. E. P, Rocha S. N, De Meyer S. F, Uji-I H, Deckmyn H, Hofkens J, Vanhoorelbeke K
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 11, 120, 121, Jul. 2013, [Peer-reviewed]
English - Chitosan as matrix for bio-polymer dispersed liquid crystal systems
Luminita Marin, Maria-Cristina Popescu, Andrei Zabulica, Hiroshi Uji-, Eduard Fron
CARBOHYDRATE POLYMERS, 95, 1, 16, 24, May 2013, [Peer-reviewed]
English, Scientific journal - Accelerating the Phase Separation in Aqueous Poly(N-isopropylacrylamide) Solutions by Slight Modification of the Polymer Stereoregularity: A Single Molecule Fluorescence Study
Takanori Tada, Yukiteru Katsumoto, Karel Goossens, Hiroshi Uji-i, Johan Hofkens, Tatsuya Shoji, Noboru Kitamura, Yasuyuki Tsuboi
JOURNAL OF PHYSICAL CHEMISTRY C, 117, 20, 10818, 10824, May 2013, [Peer-reviewed]
English, Scientific journal - Self-Assembled Organic Microfibers for Nonlinear Optics
Jialiang Xu, Sergey Semin, Dorota Niedzialek, Paul H. J. Kouwer, Eduard Fron, Eduardo Coutino, Matteo Savoini, Yuliang Li, Johan Hofkens, Hiroshi Uji-, David Beljonne, Theo Rasing, Alan E. Rowan
ADVANCED MATERIALS, 25, 14, 2084, 2089, Apr. 2013, [Peer-reviewed]
English, Scientific journal - Silver nanowires terminated by metallic nanoparticles as effective plasmonic antennas
Bart Kenens, Maksym Rybachuk, Johan Hofkens, Hiroshi Uji-I
Journal of Physical Chemistry C, 117, 6, 2547, 2553, 14 Feb. 2013, [Peer-reviewed]
English, Scientific journal - Excitation Polarization Sensitivity of Plasmon-Mediated Silver Nanotriangle Growth on a Surface
Aniruddha Paul, Bart Kenens, Johan Hofkens, Hiroshi Uji-i
LANGMUIR, 28, 24, 8920, 8925, Jun. 2012, [Peer-reviewed]
English, Scientific journal - Mapping of Surface-Enhanced Fluorescence on Metal Nanoparticles using Super-Resolution Photoactivation Localization Microscopy
Hongzhen Lin, Silvia P. Centeno, Liang Su, Bart Kenens, Susana Rocha, Michel Sliwa, Johan Hofkens, Hiroshi Uji-i
CHEMPHYSCHEM, 13, 4, 973, 981, Mar. 2012, [Peer-reviewed]
English, Scientific journal - Photocatalytic growth of dendritic silver nanostructures as SERS substrates
Katrien G. M. Laurier, Michel Poets, Frederik Vermoortele, Gert De Cremer, Johan A. Martens, Hiroshi Uji-i, Dirk E. De Vos, Johan Hofkens, Maarten B. J. Roeffaers
CHEMICAL COMMUNICATIONS, 48, 10, 1559, 1561, 2012, [Peer-reviewed]
English, Scientific journal - Excitation wavelength dependent surface enhanced Raman scattering of 4-aminothiophenol on gold nanorings
Jian Ye, James Andell Hutchison, Hiroshi Uji-i, Johan Hofkens, Liesbet Lagae, Guido Maes, Gustaaf Borghs, Pol Van Dorpe
NANOSCALE, 4, 5, 1606, 1611, 2012, [Peer-reviewed]
English, Scientific journal - The Origin of Heterogeneity of Polymer Dynamics near the Glass Temperature As Probed by Defocused Imaging
Ania Deres, George A. Floudas, Klaus Muellen, Mark Van der Auweraer, Frans De Schryver, Joerg Enderlein, Hiroshi Uji-i, Johan Hofkens
MACROMOLECULES, 44, 24, 9703, 9709, Dec. 2011, [Peer-reviewed]
English, Scientific journal - Quantitative Multicolor Super-Resolution Microscopy Reveals Tetherin HIV-1 Interaction
Martin Lehmann, Susana Rocha, Bastien Mangeat, Fabien Blanchet, Hiroshi Uji-i, Johan Hofkens, Vincent Piguet
PLOS PATHOGENS, 7, 12, Dec. 2011, [Peer-reviewed]
English, Scientific journal - Local Elongation of Endothelial Cell-anchored von Willebrand Factor Strings Precedes ADAMTS13 Protein-mediated Proteolysis
Karen De Ceunynck, Susana Rocha, Hendrik B. Feys, Simon F. De Meyer, Hiroshi Uji-i, Hans Deckmyn, Johan Hofkens, Karen Vanhoorelbeke
JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 42, 36361, 36367, Oct. 2011, [Peer-reviewed]
English, Scientific journal - Single molecule study of polymers
Johan Hofkens, Hiroshi Uji-i
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 242, Aug. 2011, [Peer-reviewed]
English - Local stretching of VWF strings is a trigger for ADAMTS13 mediated proteolysis
K. E. De Ceunynck, S. Rocha, H. B. Feys, S. F. De Meyer, H. Deckmyn, H. Uji-I, J. Hofkens, K. Vanhoorelbeke
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9, 308, 308, Jul. 2011, [Peer-reviewed]
English - Light-assisted nucleation of silver nanowires during polyol synthesis
Hongzhen Lin, Tatsumi Ohta, Aniruddha Paul, James A. Hutchison, Kirilenko Demid, Oleg Lebedev, Gustaaf Van Tendeloo, Johan Hofkens, Hiroshi Uji-i
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 221, 2-3, 220, 223, Jun. 2011, [Peer-reviewed]
English, Scientific journal - Quantitative multicolour super-resolution microscopy reveals tetherin HIV-1 interaction
M. Lehmann, S. Rocha, B. Mangeat, F. Blanchet, H. Uji-i, J. Hofkens, V. Piguet
BRITISH JOURNAL OF DERMATOLOGY, 164, 4, 918, 918, Apr. 2011, [Peer-reviewed]
English - Direct Patterning of Oriented Metal-Organic Framework Crystals via Control over Crystallization Kinetics in Clear Precursor Solutions
Rob Ameloot, Elena Gobechiya, Hiroshi Uji-i, Johan A. Martens, Johan Hofkens, Luc Alaerts, Bert F. Sels, Dirk E. De Vos
ADVANCED MATERIALS, 22, 24, 2685, +, Jun. 2010, [Peer-reviewed]
English, Scientific journal - Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A(2) Action at the Single Molecule Level
Martin Gudmand, Susana Rocha, Nikos S. Hatzakis, Kalina Peneva, Klaus Muellen, Dimitrios Stamou, Hiroshi Uji-I, Johan Hofkens, Thomas Bjornholm, Thomas Heimburg
BIOPHYSICAL JOURNAL, 98, 9, 1873, 1882, May 2010, [Peer-reviewed]
English, Scientific journal - Unraveling Excited-State Dynamics in a Polyfluorene-Perylenediimide Copolymer
Eduard Fron, Ania Deres, Susana Rocha, Gang Zhou, Klaus Muellen, Frans C. De Schryver, Michel Sliwa, Hiroshi Uji-i, Johan Hofkens, Tom Vosch
JOURNAL OF PHYSICAL CHEMISTRY B, 114, 3, 1277, 1286, Jan. 2010, [Peer-reviewed]
English, Scientific journal - Watching Individual Enzymes at Work
Kerstin Blank, Susana Rocha, Gert De Cremer, Maarten B. J. Roeffaers, Hiroshi Uji-i, Johan Hofkens
SINGLE MOLECULE SPECTROSCOPY IN CHEMISTRY, PHYSICS AND BIOLOGY, 96, 495, +, 2010, [Peer-reviewed]
English, International conference proceedings - Focusing Plasmons in Nanoslits for Surface-Enhanced Raman Scattering
Chang Chen, James Andell Hutchison, Pol Van Dorpe, Ronald Kox, Iwijn De Vlaminck, Hiroshi Uji-i, Johan Hofkens, Liesbet Lagae, Guido Maes, Gustaaf Borghs
SMALL, 5, 24, 2876, 2882, Dec. 2009, [Peer-reviewed]
English, Scientific journal - Synthesis, Ensemble, and Single Molecule Characterization of a Diphenyl-Acetylene Linked Perylenediimide Trimer
Tom Vosch, Eduard Fron, Jun-ichi Hotta, Ania Deres, Hiroshi Uji-i, Abdenacer Idrissi, Jaesung Yang, Dongho Kim, Larissa Puhl, Andreas Haeuseler, Klaus Muellen, Frans C. De Schryver, Michel Sliwa, Johan Hofkens
JOURNAL OF PHYSICAL CHEMISTRY C, 113, 27, 11773, 11782, Jul. 2009, [Peer-reviewed]
English, Scientific journal - Monitoring the Interaction of a Single G-Protein Key Binding Site with Rhodopsin Disk Membranes upon Light Activation
Tai-Yang Kim, Hiroshi Uji-i, Martina Moeller, Benoit Muls, Johan Hofkens, Ulrike Alexiev
BIOCHEMISTRY, 48, 18, 3801, 3803, May 2009, [Peer-reviewed]
English, Scientific journal - Subdiffraction Limited, Remote Excitation of Surface Enhanced Raman Scattering
James A. Hutchison, Silvia P. Centeno, Hideho Odaka, Hiroshi Fukumura, Johan Hofkens, Hiroshi Uji-i
NANO LETTERS, 9, 3, 995, 1001, Mar. 2009, [Peer-reviewed]
English, Scientific journal - Defocused Wide-field Imaging Unravels Structural and Temporal Heterogeneity in Complex Systems
Peter Dedecker, Benoit Muls, Ania Deres, Hiroshi Uji-i, Jun-ichi Hotta, Michel Sliwa, Jean-Philippe Soumillion, Klaus Muellen, Joerg Enderlein, Johan Hofkens
ADVANCED MATERIALS, 21, 10-11, 1079, 1090, Mar. 2009, [Peer-reviewed]
English, Scientific journal - Linking Phospholipase Mobility to Activity by Single-Molecule Wide-Field Microscopy
Susana Rocha, James A. Hutchison, Kalina Peneva, Andreas Herrmann, Klaus Muellen, Michael Skjot, Christian I. Jorgensen, Allan Svendsen, Frans C. De Schryver, Johan Hofkens, Hiroshi Uji-i
CHEMPHYSCHEM, 10, 1, 151, 161, Jan. 2009, [Peer-reviewed]
English, Scientific journal - Polymers and single molecule fluorescence spectroscopy, what can we learn?
Dominik Woll, Els Braeken, Ania Deres, Frans C. De Schryver, Hiroshi Uji-i, Johan Hofkens
CHEMICAL SOCIETY REVIEWS, 38, 2, 313, 328, 2009, [Peer-reviewed]
English - Direct Evidence of High Spatial Localization of Hot Spots in Surface-Enhanced Raman Scattering
Chang Chen, James Andell Hutchison, Francesca Clemente, Ronald Kox, Hiroshi Uji-I, Johan Hofkens, Liesbet Lagae, Guido Maes, Gustaaf Borghs, Pol Van Dorpe
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48, 52, 9932, 9935, 2009, [Peer-reviewed]
English, Scientific journal - Control of Surface Plasmon Localization via Self-Assembly of Silver Nanoparticles along Silver Nanowires
M. Linh Tran, Silvia P. Centeno, James A. Hutchison, Hans Engelkamp, Duoduo Liang, Gustaaf Van Tendeloo, Bert F. Sels, Johan Hofkens, Hiroshi Uji-i
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, 51, 17240, +, Dec. 2008, [Peer-reviewed]
English, Scientific journal - Site-selective guest inclusion in molecular networks of butadiyne-bridged pyridino and benzeno square macrocycles on a surface
Kazukuni Tahara, Shengbin Lei, Wael Mamdouh, Yui Yamaguchi, Tomoyuki Ichikawa, Hiroshi Uji-i, Motohiro Sonoda, Keiji Hirose, Frans C. De Schryver, Steven De Feyter, Yoshito Tobe
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, 21, 6666, +, May 2008, [Peer-reviewed]
English, Scientific journal - Morphology of large ZSM-5 crystals unraveled by fluorescence microscopy
Maarten B. J. Roeffaers, Rob Ameloot, Mukulesh Baruah, Hiroshi Uji-i, Metin Bulut, Gert De Cremer, Ulrich Mueller, Pierre A. Jacobs, Johan Hofkens, Bert F. Sels, Dirk E. De Vos
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, 17, 5763, 5772, Apr. 2008, [Peer-reviewed]
English, Scientific journal - Excitation energy migration processes in cyclic porphyrin Arrays probed by single molecule spectroscopy
Jaesung Yang, Mira Park, Zin Seok Yoon, Takaaki Hori, Xiaobin Peng, Naoki Aratani, Peter Dedecker, Jun-ichi Hotta, Hiroshi Uji-i, Michel Sliwa, Johan Hofkens, Atsuhiro Osuka, Dongho Kim
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, 6, 1879, 1884, Feb. 2008, [Peer-reviewed]
English, Scientific journal - Locking of helicity and shape complementarity in diarylethene dimers on graphite
Nathalie Katsonis, Andrea Minoia, Tibor Kudernac, Toshiki Mutai, Hong Xu, Hiroshi Uji-i, Roberto Lazzaroni, Steven De Feyter, Ben L. Feringa
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130, 2, 386, +, Jan. 2008, [Peer-reviewed]
English, Scientific journal - Radical polymerization tracked by single molecule spectroscopy
Dominik Woell, Hiroshi Uji-i, Tobias Schnitzler, Jun-ichi Hotta, Peter Dedecker, Andreas Herrmann, Frans C. De Schryver, Klaus Muellen, Johan Hofkens
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47, 4, 783, 787, 2008, [Peer-reviewed]
English, Scientific journal - Water-soluble monofunctional perylene and terrylene dyes: Powerful labels for single-enzyme tracking
Kalina Peneva, Gueorgui Mihov, Fabian Nolde, Susana Rocha, Jun-ichi Hotta, Kevin Braeckmans, Johan Hofkens, Hiroshi Uji-i, Andreas Herrmann, Klaus Muellen
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47, 18, 3372, 3375, 2008, [Peer-reviewed]
English, Scientific journal - Subdiffraction imaging through the selective donut-mode depletion of thermally stable photoswitchable fluorophores: Numerical analysis and application to the fluorescent protein Dronpa
Peter Dedecker, Jun-Ichi Hotta, Cristina Flors, Michel Sliwa, Hiroshi Uji-, Maarten B. J. Roeffaers, Ryoko Ando, Hideaki Mizuno, Atsushi Miyawaki, Johan Hofkens
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129, 51, 16132, 16141, Dec. 2007, [Peer-reviewed]
English, Scientific journal - A stroboscopic approach for fast photoactivation-localization microscopy with Dronpa mutants
Cristina Flors, Jun-ichi Hotta, Hiroshi Uji-i, Peter Dedecker, Ryoko Ando, Hideaki Mizuno, Atsushi Miyawaki, Johan Hofkens
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129, 45, 13970, 13977, Nov. 2007, [Peer-reviewed]
English, Scientific journal - Single-molecule fluorescence spectroscopy in (bio)catalysis
Maarten B. J. Roeffaers, Gert De Cremer, Hiroshi Uji-i, Benlot Muls, Bert F. Sels, Pierre A. Jacobs, Frans C. De Schryver, Dirk E. De Vos, Johan Hofkens
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104, 31, 12603, 12609, Jul. 2007, [Peer-reviewed]
English, Scientific journal - Single-molecule spectroscopic investigation of energy migration processes in cyclic porphyrin arrays
Mira Park, Min-Chul Yoon, Zin Seok Yoon, Takaaki Hori, Xiaobin Peng, Naoki Aratani, Jun-ichi Hotta, Hiroshi Uji-i, Michel Sliwa, Johan Hofkens, Atsuhiro Osuka, Dongho Kim
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129, 12, 3539, 3544, Mar. 2007, [Peer-reviewed]
English, Scientific journal - Origin of simultaneous donor-acceptor emission in single molecules of peryleneimide-terrylenediimide labeled polyphenylene dendrimers
Sergey M. Melnikov, Edwin K. L. Yeow, Hiroshi Uji-i, Mircea Cotlet, Klaus Muellen, Frans C. De Schryver, Joerg Enderlein, Johan Hofkens
JOURNAL OF PHYSICAL CHEMISTRY B, 111, 4, 708, 719, Feb. 2007, [Peer-reviewed]
English, Scientific journal - Synthesis and adsorption of shape-persistent macrocycles containing polycyclic aromatic hydrocarbons in the rigid framework
Xiaohong Cheng, An Ver Heyen, Wael Mamdouh, Hiroshi Uji-i, Frans De Schryver, Sigurd Hoeger, Steven De Feyter
LANGMUIR, 23, 3, 1281, 1286, Jan. 2007, [Peer-reviewed]
English, Scientific journal - Space- and time-resolved visualization of acid catalysis in ZSM-5 crystals by fluorescence microscopy
Maarten B. J. Roeffaers, Bert F. Sels, Hiroshi Uji-i, Bart Blanpain, Pieter L'hoest, Pierre A. Jacobs, Frans C. De Schryver, Johan Hofkens, Dirk E. De Vos
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46, 10, 1706, 1709, 2007, [Peer-reviewed]
English, Scientific journal - Supramolecular chemistry at the liquid/solid interface a scanning tunneling microscopy approach
S. De Feyter, A. Miura, H. Uji-i, P. Jonkheijm, A. P. H. J. Schenning, E. W. Meijer, Z. Chen, F. Wuerthner, N. Schuurmans, J. van Esch, B. Feringa, F. C. De Schryver
NANOSCIENCE AND TECHNOLOGY, PTS 1 AND 2, 121-123, 369, 372, 2007, [Peer-reviewed]
English, International conference proceedings - 3D nanoscopy: Bringing biological nanostructures into sharp focus
Peter Dedecker, Cristina Flors, Jun-ichi Hotta, Hiroshi Uji-i, Johan Hofkens
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46, 44, 8330, 8332, 2007, [Peer-reviewed]
English, Scientific journal - Two-dimensional porous molecular networks of dehydrobenzo[12]annulene derivatives via alkyl chain interdigitation
Kazukuni Tahara, Shuhei Furukawa, Hiroshi Uji-i, Tsutomu Uchino, Tomoyuki Ichikawa, Jian Zhang, Wael Mamdouh, Motohiro Sonoda, Frans C. De Schryver, Steven De Feyter, Yoshito Tobe
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128, 51, 16613, 16625, Dec. 2006, [Peer-reviewed]
English, Scientific journal - Noncovalent control for bottom-up assembly of functional supramolecular wires
Josep Puigmarti-Luis, Andrea Minoia, Hiroshi Uji-i, Concepcio Rovira, Jerome Cornil, Steven De Feyter, Roberto Lazzaroni, David B. Amabilino
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128, 39, 12602, 12603, Oct. 2006, [Peer-reviewed]
English, Scientific journal - The fabrication of a thin, circular polymer film based phase shaper for generating doughnut modes
Jun-ichi Hotta, Hiroshi Uji-i, Johan Hofkens
OPTICS EXPRESS, 14, 13, 6273, 6278, Jun. 2006, [Peer-reviewed]
English, Scientific journal - Molecular geometry directed Kagome and honeycomb networks: Toward two-dimensional crystal engineering
S Furukawa, H Uji-i, K Tahara, T Ichikawa, M Sonoda, FC De Schryver, Y Tobe, S De Feyter
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128, 11, 3502, 3503, Mar. 2006, [Peer-reviewed]
English, Scientific journal - Visualizing spatial and temporal heterogeneity of single molecule rotational diffusion in a glassy polymer by defocused wide-field imaging
H Uji-i, SM Melnikov, A Deres, G Bergamini, F De Schryver, A Herrmann, K Mullen, J Enderlein, J Hofkens
POLYMER, 47, 7, 2511, 2518, Mar. 2006, [Peer-reviewed]
English, Scientific journal - Spatially resolved observation of crystal-face-dependent catalysis by single turnover counting
MBJ Roeffaers, BF Sels, H Uji-i, FC De Schryver, PA Jacobs, DE De Vos, J Hofkens
NATURE, 439, 7076, 572, 575, Feb. 2006, [Peer-reviewed]
English, Scientific journal - Probing dynamics of individual bio molecules by single molecule spectroscopy
W. Verheijen, H. Uji-i, C. Flors, J. Hotta, J. Hofkens
ULTRASENSITIVE AND SINGLE-MOLECULE DETECTION TECHNOLOGIES, 6092, 2006, [Peer-reviewed]
English, International conference proceedings - [Ru(TAP)(3)](2+)-photosensitized DNA cleavage studied by atomic force microscopy and gel electrophoresis: A comparative study
H Uji-i, P Foubert, FC De Schryver, S De Feyter, E Gicquel, A Etoc, C Moucheron, A Kirsch-De Mesmaeker
CHEMISTRY-A EUROPEAN JOURNAL, 12, 3, 758, 762, Jan. 2006, [Peer-reviewed]
English, Scientific journal - Supramolecular chemistry at the liquid/solid interface probed by scanning tunnelling microscopy
S. De Feyter, H. Uji-i, W. Mamdouh, A. Miura, J. Zhang, P. Jonkheijm, A. P. H. J. Schenning, E. W. Meijer, Z. Chen, F. Wuerthner, N. Schuurmans, J. van Esch, B. L. Feringa, A. E. Dulcey, V. Percec, F. C. De Schryver
INTERNATIONAL JOURNAL OF NANOTECHNOLOGY, 3, 4, 462, 479, 2006, [Peer-reviewed]
English, Scientific journal - Solvent controlled self-assembly at the liquid-solid interface revealed by STM
W Mamdouh, H Uji-i, JS Ladislaw, AE Dulcey, Percec, V, FC De Schryver, S De Feyter
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128, 1, 317, 325, Jan. 2006, [Peer-reviewed]
English, Scientific journal - Direct measurement of the end-to-end distance of individual polyfluorene polymer chains
B Muls, H Uji-i, S Melnikov, A Moussa, W Verheijen, JP Soumillion, J Josemon, K Mullen, J Hofkens
CHEMPHYSCHEM, 6, 11, 2286, 2294, Nov. 2005, [Peer-reviewed]
English, Scientific journal - Image contrast analysis of STM images of self-assembled dioctadecyl chalcogenides on graphite at the liquid-solid interface
H Fukumura, D L-i, H Uji-i, S Nishio, H Sakai, A Ohuchi
CHEMPHYSCHEM, 6, 11, 2383, 2388, Nov. 2005, [Peer-reviewed]
English, Scientific journal - Self-assembly of tetrathiafulvalene derivatives at a liquid/solid interface - compositional and constitutional influence on supramolecular ordering
MMS Abdel-Mottaleb, E Gomar-Nadal, M Surin, H Uji-i, W Mamdouh, J Veciana, Lemaur, V, C Rovira, J Cornil, R Lazzaroni, DB Amabilino, S De Feyter, FC De Schryver
JOURNAL OF MATERIALS CHEMISTRY, 15, 43, 4601, 4615, Nov. 2005, [Peer-reviewed]
English - Scanning tunneling microscopy and spectroscopy of donor-acceptor-donor triads at the liquid/solid interface
H Uji-i, A Miura, A Schenning, EW Meijer, ZJ Chen, F Wurthner, FC De Schryver, M Van der Auweraer, S De Feyter
CHEMPHYSCHEM, 6, 11, 2389, 2395, Nov. 2005, [Peer-reviewed]
English, Scientific journal - Formation of molecular wires by nanospace polymerization of a diacetylene derivative induced with a scanning tunneling microscope at a solid-liquid interface
S Nishio, D I-i, H Matsuda, M Yoshidome, H Uji-i, H Fukumura
JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS BRIEF COMMUNICATIONS & REVIEW PAPERS, 44, 7B, 5417, 5420, Jul. 2005, [Peer-reviewed]
English, Scientific journal - Electronic properties of a pi-stacked pyrene derivative at a liquid-solid interface studied with scanning tunneling spectroscopy
H Uji-i, S Nishio, H Fukumura
CHEMICAL PHYSICS LETTERS, 408, 1-3, 112, 117, Jun. 2005, [Peer-reviewed]
English, Scientific journal - Towards supramolecular electronics
APHJ Schenning, P Jonkheijm, FJM Hoeben, J van Herrikhuyzen, SCJ Meskers, EW Meijer, LM Herz, C Daniel, C Silva, RT Phillips, RH Friend, D Beljonne, A Miura, S De Feyter, M Zdanowska, H Uji-i, FC De Schryver, Z Chen, F Wurthner, M Mas-Torrent, D den Boer, M Durkut, P Hadley
SYNTHETIC METALS, 147, 1-3, 43, 48, Dec. 2004, [Peer-reviewed]
English, Scientific journal - Structure of intermolecular donor-acceptor monolayers of N,N-dimethyl-p-[15-(1-pyrenyl)pentadecanyl]aniline
S Nishio, M Yoshidome, H Uji-i, J Hobley, H Fukumura, KA Zachariasse
CHEMISTRY LETTERS, 33, 11, 1506, 1507, Nov. 2004, [Peer-reviewed]
English, Scientific journal - Design and STM investigation of intramolecular folding in self-assembled monolayers on the surface
N Schuurmans, H Uji-i, W Mamdouh, FC De Schryver, BL Feringa, J van Esch, S De Feyter
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126, 43, 13884, 13885, Nov. 2004, [Peer-reviewed]
English, Scientific journal - A nanoscale view of supramolecular stereochemistry in self-assembled monolayers of enantiomers and racemates
W Mamdouh, H Uji-i, A Gesquiere, S De Feyter, DB Amabilino, MMS Abdel-Mottaleb, J Veciana, FC De Schryver
LANGMUIR, 20, 22, 9628, 9635, Oct. 2004, [Peer-reviewed]
English, Scientific journal - Expression of molecular chirality and two-dimensional supramolecular self-assembly of chiral, racemic, and achiral monodendrons at the liquid-solid interface
W Mamdouh, H Uji-i, AE Dulcey, Percec, V, S De Feyter, FC De Schryver
LANGMUIR, 20, 18, 7678, 7685, Aug. 2004, [Peer-reviewed]
English, Scientific journal - Bias-dependent visualization of electron donor (D) and electron acceptor (A) moieties in a chiral DAD triad molecule
A Miura, ZJ Chen, H Uji-i, S De Feyter, M Zdanowska, P Jonkheijm, APHJ Schenning, EW Meijer, F Wurthner, FC De Schryver
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 125, 49, 14968, 14969, Dec. 2003, [Peer-reviewed]
English, Scientific journal - Nanospark at the interface between organic solvents and tin-doped indium oxide
H Uji-i, K Hatanaka, J Hobley, H Fukumura
APPLIED PHYSICS LETTERS, 79, 16, 2660, 2662, Oct. 2001, [Peer-reviewed]
English, Scientific journal - Sub-micrometer photochromic patterns using laser induced molecular implantation techniques (LIMIT)
J Hobley, M Goto, M Kishimoto, H Fukumura, H Uji-I, M Irie
MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 345, 623, +, 2000, [Peer-reviewed]
English, Scientific journal - A knowledge structure visualization for supporting exploratory learning in hyperspace
A Kashihara, H Uji'i, J Toyoda
ARTIFICIAL INTELLIGENCE IN EDUCATION, 50, 714, 716, 1999, [Peer-reviewed]
English, International conference proceedings - Laser implantation of photochromic molecules into polymer films: a new approach towards molecular device fabrication
H Fukumura, H Uji-i, H Banjo, H Masuhara, DM Karnakis, N Ichinose, S Kawanishi, K Uchida, M Irie
APPLIED SURFACE SCIENCE, 127, 761, 766, May 1998, [Peer-reviewed]
English, Scientific journal
Other Activities and Achievements
- 研究者の最新動向 ナノ・プロドラッグ 新たな抗がん薬輸送システムの細胞内挙動
小関 良卓, Taemaitree Farsai, Fortuni Beatrice, Rocha Susana, 雲林院 宏, 猪瀬 朋子, 笠井 均, Precision Medicine, 4, 8, 753, 758, Aug. 2021
(株)北隆館, Japanese - ナノ・プロドラッグ:新たな抗がん薬輸送システムの細胞内挙動
小関 良卓, Taemaitree Farsai, Fortuni Beatrice, Rocha Susana, 雲林院 宏, 猪瀬 朋子, 笠井 均, 細胞, 52, 13, 769, 773, Nov. 2020
(株)ニュー・サイエンス社, Japanese - プラズモン導波路を用いた単一細胞解析と操作
豊内 秀一, 猪瀬 朋子, 平井 健二, 雲林院 宏, 細胞, 52, 2, 97, 100, Feb. 2020
(株)ニュー・サイエンス社, Japanese - プラズモン導波路を用いた単一細胞解析と操作
豊内秀一, 猪瀬朋子, 平井健二, 雲林院宏, 月間「細胞」2020年 2月号, 51, 54, 2020 - Super-resolution microscopy using chemically-synthesized noble metal nanowires
藤田康彦, 猪瀬朋子, 雲林院宏, 光化学, 48, 1, 2, 9, 2017, [Peer-reviewed]
光化学協会, Japanese, Introduction scientific journal - プラズモン導波路ナノ光源を用いた単一細胞内局所分光技術
猪瀬朋子, 藤田康彦, 雲林院宏, 生物物理, 56, 6, 327, 329, 2016, [Peer-reviewed]
(一社)日本生物物理学会, Japanese, Introduction scientific journal - 光の回折限界を超える蛍光顕微鏡法PALMによる細胞内微小構造の観察
Rocha Susana, De Keersmaecker Herlinde, 阿部 充宏, 雲林院 宏, Hofkens Johan, 小林 俊秀, 宮脇 敦史, 水野 秀昭, 顕微鏡, 49, 3, 205, 210, Dec. 2014
(公社)日本顕微鏡学会, Japanese - Plasmonic waveguide endoscopy
Hiroshi Ujii, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 247, Mar. 2014
English, Summary international conference - New insight into molecular recognition: Coupling of single G-proteins to active rhodopsin
Ulrike Alexiev, Martina Moeller, Tai-Yang Kim, Kathrin Winkler, Hiroshi Ujii, Benoit Muls, Johan Hofkens, BIOPHYSICAL JOURNAL, 187A, 187A, Jan. 2007
English, Summary international conference - Structural variations in self-assembled monolayers of 1-pyrenehexadecanoic acid and 4,4 '-bipyridyl on graphite at the liquid-solid interface
H Uji, M Yoshidome, J Hobley, K Hatanaka, H Fukumura, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 5, 19, 4231, 4235, Oct. 2003
English
Research Themes
- Strong Coupling at Meso-Hierarchy
Grants-in-Aid for Scientific Research
01 Apr. 2023 - 31 Mar. 2028
雲林院 宏, 平井 健二, 五月女 光
Japan Society for the Promotion of Science, Grant-in-Aid for Transformative Research Areas (A), Hokkaido University, 23H04877 - Science of Meso-Hierarchy
Grants-in-Aid for Scientific Research
01 Apr. 2023 - 31 Mar. 2028
矢貝 史樹, 雲林院 宏, VACHA Martin, 相良 剛光, 羽會部 卓, 原野 幸治, 重田 育照
Japan Society for the Promotion of Science, Grant-in-Aid for Transformative Research Areas (A), Chiba University, 23H04872 - がん細胞特有の刺激に応答し薬物を放出する新規抗がん薬ナノ粒子の開発
科学研究費助成事業
01 Apr. 2022 - 31 Mar. 2026
笠井 均, 小関 良卓, 雲林院 宏, 根本 知己, 石岡 千加史
日本学術振興会, 基盤研究(A), 東北大学, 22H00328 - Knowledge-driven Nanodrug design through understanding of a role of Phase-separated condensate in chemotherapy using Single-Cell endoscopy
Grants-in-Aid for Scientific Research
05 Apr. 2021 - 31 Mar. 2025
雲林院 宏, 松崎 典弥, 金蔵 孝介, 猪瀬 朋子, 笠井 均
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A), Hokkaido University, 21H04634 - Bioactive gas pump-probe method elucidates the relationship of nitric oxide diffusion with vascular function
Grants-in-Aid for Scientific Research
09 Jul. 2021 - 31 Mar. 2024
古川 修平, 猪瀬 朋子, 亀井 謙一郎, 雲林院 宏
心疾患と脳血管疾患は、長年日本における死因の第2, 3位を占めており、今後社会の高齢化が加速する中で、その治療は公衆衛生上最も重要な課題の一つである。生体内で産生されるNOは、血管弛緩・拡張を惹起することが知られており、その効果を活用した治療薬への応用が期待されている。しかしながら、現在の治療法ではNOを体内の狙った場所へ伝達することが困難であり、今後NOをより汎用性の高い治療薬として活用するためには、治療部位でのNOガス拡散の時空間的挙動と血管機能の相関を解明し、必要最低限のNOの利用へとつなげる必要がある。 本研究「生体ガスポンプ・プローブ法を用いた一酸化窒素拡散挙動と血管機能相関の可視化」では、血管機能の制御・改善に向け、一酸化窒素 (NO)を放出する多孔性ナノ粒子を用いて、単一細胞内・血管組織におけるNOの拡散ダイナミクス及び空間分布情報とNOにより惹起される細胞機能の相関を可視化し、生体内NOの真の挙動を明らかにする。
初年度は、細胞内におけるNOの発生位置を固定するために、単一細胞内視鏡技術に用いる銀ナノワイヤー上に光によりNO発生が可能な亜鉛とニトロイミダゾールからなる多孔性金属錯体（NOF-1)の固定化技術の確立を目指した。様々な合成条件（反応温度、試薬濃度、ナノワイヤー分散度）の検討の結果、銀ナノワイヤー上へのNOF-1の固定化条件を見出した。また、同様の条件を用いることで、銀ナノワイヤーのみならず金ナノロッド上への固定化にも成功した。
Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Research (Pioneering), Kyoto University, 21K18192 - 液中原子分解能AFM探針の革新：分子精密設計および単分子評価によるアプローチ
科学研究費助成事業
09 Jul. 2021 - 31 Mar. 2023
淺川 雅, 古山 渓行, 雲林院 宏
原子間力顕微鏡（AFM）に用いる探針の終端構造を単原子レベルで精密設計することで、液中原子分解能AFM像の解釈を「推測」から「原子・分子スケールで理解する」ことへ進化させることを目指している。探針先端の精密設計は液中AFM計測の再現性を大幅に向上することにも繋がるため、専門家でなくても液中原子スケールAFM計測が実現できる汎用レベルの基盤的分析手法へ発展できる。そこで構造有機化学分野の精密分子設計の知見から、観察試料と相互作用する探針先端が高い再現性で同じ化学構造を持ったAFM探針を調製する方法論を検討してきた。探針先端に取り付ける骨格構造には三角錐の頂点に3つの架橋構造と1つの終端構造を持ついくつかの剛直分子を候補として計画し、テトラフェニルメタン分子やその他の骨格構造の有機合成を行なった。またシリコン製探針の先端への架橋方法について、シラン化やホスホン酸を用いたカップリング反応条件の検討・最適化を進めた。さらに探針先端に骨格構造を取り付けた後の評価手法として、終端構造に蛍光分子を導入し、3次元分子配向に加えて回転・揺らぎなどのダイナミクスを直接計測できるdefocused imagingを実施するための装置設計を実施した。AFM装置と蛍光観察装置を融合したシステムにより探針先端の1分子スケール評価を実現するために、アクティブ除振台にAFMと同時に配置できる光学系の構築を完了した。
日本学術振興会, 挑戦的研究(萌芽), 金沢大学, 21K18871 - 原子層ヘテロ接合部の超高空間分解能振動情報・発光特性解析
科学研究費助成事業
01 Apr. 2020 - 31 Mar. 2023
猪瀬 朋子, 雲林院 宏, 宮田 耕充
遷移金属ジカルコゲナイド（TMDs）シートの電子供与体および電子受容体分子による表面修飾は、TMDsの電子状態操作が可能なため、TMDs発光特性の制御に利用されている。本年度、代表者はまず、分担者・宮田作製のWSe2シートにテトラフルオロ-1,4-ベンゾキノン（TFBQ）を修飾した後、修飾したシートのラマン分光・蛍光発光測定を行い、WSe2シート層数と発光特性の相関を明らかにすることを目指した。具体的には、まず、TFBQ修飾前のCVD法で合成されたSi基板上WSe2シートの発光スペクトル測定を行い、観察されたスペクトルのピーク波長でWSe2シートのマッピングを行った。その結果、シート層数の増加に伴い、発光スペクトルピークの長波長シフトが確認された。これは、層数増加に伴いバンドギャップが小さくなることに由来する。また、多層部位では間接遷移型に伴う蛍光強度の低下が確認された。このような、層数増加に伴う発光スペクトルの長波長シフトおよび発光強度の低下は、TFBQ修飾後においても観察された。TFBQ修飾前と比較すると、TFBQ修飾後、WSe2シートの発光スペクトルの短波長シフトが確認され、また、単層よりも二層領域でより大きな短波長シフトが観察された。これは、TFBQのWSe2シート酸化作用により、トリオンの生成が抑制され、エキシトン発光の影響が大きくなったためと考察される。また、トリオンの束縛エネルギーが小さい二層部位においては、酸化によるより大きな短波長シフトが観察された。この結果から、本年度は、光学顕微鏡を用いてWSe2シート層数と発光特性の相関を確認することができ、さらに、WSe2シート2層の領域で、より顕著な発光特性変化を確認することに成功した。
日本学術振興会, 基盤研究(C), 京都大学, 20K05413 - Plasmonic waveguiding remote surface enhanced fluorescence microscopy
Grants-in-Aid for Scientific Research
30 Jul. 2020 - 31 Mar. 2022
Hiroshi Uji-i
In this study, we aimed to develop a new "remote-excitation probe-enhanced fluorescence (RE-TEF) microscope" with high spatial resolution of less than 10 nm by introducing silver nanowires (AgNWs) of 100 nm in diameter and several tens of um in length, chemically synthesized to function as a plasmon waveguide, on an AFM cantilever In this study, we comparatively developed a method of galvanic substitution reaction, photo-induced local deposition of gold nanoparticles, and alignment of two AgNWs to couple far-field light in propagating plamons. These probes enable spectral mapping with a spatial resolution of about 50-100 nm, which is useful for novel optical DNA mapping analysis.
Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Research (Exploratory), Hokkaido University, 20K21165 - Elucidation of the Unzip Mechanism to Form Single-layer Graphene Nanoribbons and the Creation of Innovative Functions
Grants-in-Aid for Scientific Research
01 Apr. 2019 - 31 Mar. 2022
Tanaka Hirofumi
Many of the wiring in semiconductor circuits such as LSIs are made of metal and are facing problems such as increasion of resistance due to miniaturization, etc. Since GNR is a good conductor with a thickness of 0.3 nm, if it can be used for nano wiring, it will have a great impact on the semiconductor industry. In this project, we performed (1) developing multifunctional GNRs obtained by unzipping using a radical initiator, (2) develop a new method of briding GNR by dielectrophoresis. (3) Theoretical consideration of conditions for bridging only GNRs by dielectrophoresis from a mixed suspension of GNRs and SWNTs. and (4) Evaluation of the edge structure of GNRs obtained by unzipping using the probe-enhanced Raman method, and other significant results contributing to the development of this field were obtained.
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B), Kyushu Institute of Technology, 19H02559 - Laser Heating for Three-Dimensional Material Synthesis
Grants-in-Aid for Scientific Research
01 Apr. 2018 - 31 Mar. 2021
Hirai Kenji
The methodology to synthesize functional materials at the desired positions is essential to fully utilize their functionality. In this project, we prepared silver nanowire (AgNW) where a gold nanoparticle (AuNP) is deposited. By manipulating AgNW and laser irradiation on AuNP, the heating from AuNP is spatially controllable. This methodology enables to synthesize ZnO and metal-organic frameworks (MOFs) at desired positions.
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B), Hokkaido University, 18H01948 - Single cell interrogation for drug delivery system
Grants-in-Aid for Scientific Research
01 Apr. 2017 - 31 Mar. 2021
Uji-i Hiroshi
The aim of this study is to follow the intracellular dynamics of drug delivery systems (DDS) by optical microscopy and to understand the drug properties using nanowire-enhanced Raman microscopy (NW-SERS) developed by this researcher. In this project, we synthesized "active DDS particles" modified with hyaluronic acid, which is a ligand for glycoproteins expressed on the surface of lung cancer cells (A549), and delivered the anticancer drug into the cells with the ligand-modified DDS particles. In addition to this, we found that the anticancer drug molecules interacted with DNA much more quickly than when delivered alone. Furthermore, differences in the subcellular localization of the anticancer drug molecules were also observed, which may affect the drug efficacy characteristics.
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B), Hokkaido University, 17H03003 - remote excitation of optical trapping using plasmonic waveguide
Grants-in-Aid for Scientific Research
01 Apr. 2017 - 31 Mar. 2019
雲林院 宏
物理学から生物学まで、広い分野で応用されている光圧は遠方場から近接場へとその舞台を変えつつある。その中で、局在プラズモン共鳴（LSPR）はナノ物質輸送への応用が期待されている。本研究では、複数のプラズモン導波路を利用したリモート励起多機能光トラッピングを新たに提案する。導波路を伝わる伝搬プラズモンにより導波路先端でLSPRを励起（リモート励起）し、複数の導波路を交互にON/OFFすることによってLSPR位置をnmレベルで動的に制御する方法を新たに開発する。さらに、nm領域でトラップされている物質輸送の様子を、光学顕微鏡で観測する手法を新たに提案・開発することを目的とした。
本研究では、プラズモン導波路としては、化学的に合成した減衰係数の低い径１００ナノメートル、長さ１０から２０ マイクロメートル程度の銀ナノワイヤーを用いた。近赤外フェムト秒レーザー光をプラズモン導波路に伝搬させると、導波路上を光が伝搬している部分では３次の非線形現象である４波混合が優先的に起こり、導波路の端では２次の非線形である和収差や第２次高調波が優先的に起こることを、蛍光顕微鏡を駆使することで実験的に証明した。この現象を利用し、 2次の非線形光学現象である和収差に共鳴する量子ドットは導波路の両端のみにトラップされるが、3次の非線形現象である４波混合と共鳴する量子ドットは導波路全体にトラップされることを見出した。これにより、非線形光学現象によって、光トラップの場所依存の制御の可能性を初めて示唆した。
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Hokkaido University, 17H05458 - Control of plasmon-associated multi-photon photochromic reaction at nanometer scale
Grants-in-Aid for Scientific Research
01 Apr. 2017 - 31 Mar. 2019
雲林院 宏
分子・光結合は量子情報システムや微弱光スイッチングデバイスなどへの応用が期待されている一方で、複雑な設計が要求され、かつ室温での操作が困難である。反面、局在プラズモン共鳴は光エネルギーをnmスケールに閉じ込め、そのスケールで分子と光の相互作用を引き起こすことが可能である。近年、この特性を生かした室温での分子・光結合の実現を試みる研究が世界的に多くなされている。本研究では、さらに一歩進めて、プラズモン増強多光子励起過程を巧みに利用して、nmスケールで化学反応を制御することを目指した。具体的には、局在プラズモン共鳴増強を利用して、多光子励起異性化反応をnmスケールで制御し、かつそれにより巨視的光応答性制御を実現する新手法を開発する。本研究では，局所プラズモン共鳴増強を利用して、多光子励起による光異性化反応をnmスケールで制御し、それにより巨視的光応答性制御を実現する新手法の開発を目指した。
具体的には、化学合成によって得られた銀ナノワイヤー（AgNW）上での蛍光性ジアリルエテン（fDAE）誘導体の非線形光学光異性化反応について調べた。使用したfDAE誘導体は、閉環構造で蛍光を発し、開環構造では蛍光を発さない。近赤外フェムト秒レーザーをプラズモン導波路であるAgNW上に伝搬させたときに、蛍光体と非蛍光体が繰り返し観測されれば、伝搬光により異性化反応が制御されている証拠となる。820nmの励起光を伝搬させると、その強度が高い場合、３光子吸収による閉環反応が誘起されて蛍光を発し、強度が弱い場合は２光子励起による開環反応が優先的に誘起されて蛍光が消光した。これにより、プラズモン導波路を伝搬する近赤外光により、光反応を多光子過程で誘起することが可能であることを初めて明らかにした。これにより、 プラズモンを利用することで、多光子光反応のnmスケールでの制御を達成した。
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Hokkaido University, 17H05244
