Research activity information

• Cep192 insufficiency underlies haploid instability in human cells
  Ryota Uehara; Koya Yoshizawa; Hemang Raj Singh; Kathirvel Paramasivam; Jin Zhu
  28 Apr. 2026
• Comparative Pharmacological Analysis of Mitotic Inhibitors Using Isogenic Ploidy Series of HAP1 Cells
  Koya Yoshizawa; Ryota Uehara
  Methods in Molecular Biology, 2025
  English
• Fragility of ER homeostatic regulation underlies haploid instability in human somatic cells
  Sumire Ishida-Ishihara; Kan Yaguchi; Sena Miura; Ryoto Nomura; QiJiao Wang; Koya Yoshizawa; Kimino Sato; Guang Yang; Krisztina Veszelyi; Gabor Banhegyi; Eva Margittai; Ryota Uehara
  Journal of Biological Chemistry, Nov. 2024
  Scientific journal
• Photoswitchable Auxin-Inducible Degron System for Conditional Protein Degradation with Spatiotemporal Resolution
  Saugata Sahu; Koya Yoshizawa; Takahiro Yamamoto; Ryota Uehara; Nobuyuki Tamaoki
  Journal of the American Chemical Society, 07 Aug. 2024
  Scientific journal
• Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells
  Koya Yoshizawa; Akira Matsura; Masaya Shimada; Sumire Ishida‐Ishihara; Fuyu Sato; Takahiro Yamamoto; Kan Yaguchi; Eiji Kawamoto; Taruho Kuroda; Kazuya Matsuo; Nobuyuki Tamaoki; Ryuichi Sakai; Yasuhito Shimada; Mithilesh Mishra; Ryota Uehara
  Molecular Oncology, Cold Spring Harbor Laboratory, Jun. 2023
  Scientific journal
• Mevalonate Pathway-mediated ER Homeostasis Is Required for Haploid Stability in Human Somatic Cells
  Kan Yaguchi; Kimino Sato; Koya Yoshizawa; Daisuke Mikami; Kohei Yuyama; Yasuyuki Igarashi; Gabor Banhegyi; Eva Margittai; Ryota Uehara
  Cell Structure and Function, 46, 1, 1, 9, Japan Society for Cell Biology, 2021
  English, Scientific journal
• Uncoupling of DNA Replication and Centrosome Duplication Cycles Is a Primary Cause of Haploid Instability in Mammalian Somatic Cells
  Yoshizawa, K.; Yaguchi, K.; Uehara, R.
  Frontiers in Cell and Developmental Biology, 8, 2020
  Scientific journal