博士, 獣医学, 北海道大学

臨床獣医学

Life Science, Veterinary medical science, Veterinary clinical medicine, Small animal gastroenterology, Veterinary internal medicine

Doctoral (PhD) degree program, Graduate School of Veterinary Medicine

Aug. 2024, 北海道獣医師会 令和6年度北海道地区学会, 北海道地区学会長賞
ラブラドール・レトリーバーのコロニーで集団発生したサルファ剤過敏症とCYPB5Rの遺伝子型頻度解析
岸原 果子;横山 望;山崎 淳平;笹岡 一慶;森下 啓太郎;中村 健介;宮原 和郎;近藤 厚;滝口 満喜;高橋 徹

Feb. 2023, 日本獣医内科学アカデミー, 第19回日本獣医内科学アカデミー学術大会 症例検討アワード
新規遺伝子変異を同定した猫の肥大型筋ジストロフィーの1例
山口敬央;横山 望;山崎淳平;松本悠貴;岡田一喜;木之下怜平;新坊弦也;卯川尚史;石井隆雅;中村健介;滝口満喜

Sep. 2022, 北海道獣医師会 令和4年度北海道地区学会, 北海道獣医師会長賞
低コレステロール血症は犬の膵外分泌不全を予測できるのか？
横山 望, 大田 寛, 永田矩之, 笹岡一慶, 新坊弦也, 佐々木 東, 森下啓太郎, 中村健介, 滝口満喜, Japan society, Japan

Mar. 2016, クリニカルニュートリション研究会, スカラーシッププログラム奨励研究アワード
犬の慢性腸症における血中微量元素プロファイルの解析
横山 望

Exploring DNA methylation profiles in blood samples of canine gastrointestinal lymphoma
Miyuki Nakamura; Yuki Matsumoto; Masatoshi Nagata; Keiji Yasuda; Kei Yonekawa; Shigeki Muramatsu; Anna Goshima; Ryo Nakaki; Nozomu Yokoyama; Ko Nakashima; Masahiro Okumura; Jumpei Yamazaki
PLOS One, 20, 12, e0339388, e0339388, Public Library of Science (PLoS), 30 Dec. 2025
Scientific journal, Blood-based testing represents a valuable tool for the detection and monitoring of patient conditions in both human and veterinary medicine. When conventional tissue-based diagnosis is challenging, blood-derived measurements allow for minimally invasive testing. Recent studies across mammalian species, particularly in humans, have explored the use of DNA methylation from whole blood, revealing its potential to predict individual mortality and responses to environmental stresses. While it is well recognized that tumor lesions display altered epigenetic modifications across some mammalian species, little is known about how DNA methylation in blood, as an indirect tissue sample, reflects the status of individuals in dogs. In this study, we conducted whole genome bisulfite sequencing using whole blood samples from twenty dogs diagnosed with canine gastrointestinal lymphoma, which is a prevalent disease in dogs. Comparative analysis with non-lymphoma controls identified over one thousand differentially methylated regions (DMRs). To develop practical predictive models, we narrowed down the number of DMRs from the total identified to a feasible set of probes using machine learning, achieving high accuracy (0.8–0.9) in predicting lymphoma cases. Our research underscores the potential of utilizing DNA methylation from whole blood as predictors and establishes a foundational data infrastructure for genome-wide DNA methylation for canine health monitoring for future studies.

Potential human health risk of carbapenem-non-susceptible Pseudomonas aeruginosa from companion animals
Jirachaya Toyting-Hiraishi; Toyotaka Sato; Mana Tohyama; Taro Fujino; Kaho Okada; Kazuyoshi Sasaoka; Nozomu Yokoyama; Kana Torii; Akio Suzuki; Yuzo Tsuyuki; Kensuke Nakamura; Mitsuyoshi Takiguchi; Motohiro Horiuchi
Journal of Antimicrobial Chemotherapy, 04 Nov. 2025
Scientific journal

Feasibility of Shear Wave Elastography and Dispersion Imaging in the Evaluation of Hepatic and Renal Congestion in Dogs
Nozomi Shiohara; Kensuke Nakamura; Keitaro Morishita; Nozomu Yokoyama; Mei Sugawara‐Suda; Mitsuyoshi Takiguchi
Veterinary Radiology & Ultrasound, Nov. 2025
Scientific journal

Deep-learning-based automatic liver segmentation using computed tomography images in dogs
Seungyeon Lee; Genya Shimbo; Nozomu Yokoyama; Kensuke Nakamura; Ren Togo; Takahiro Ogawa; Miki Haseyama; Mitsuyoshi Takiguchi
Frontiers in Veterinary Science, 12, Frontiers Media SA, 21 Oct. 2025
Scientific journal, Introduction

Deep learning-based automated segmentation has significantly improved the efficiency and accuracy of human medicine applications. However, veterinary applications, particularly canine liver segmentation, remain limited. This study aimed to develop and validate a deep learning model based on a 3D U-Net architecture for automated liver segmentation in canine abdominal computed tomography (CT) scans.

Methods

A total of 221 canine abdominal CT scans were analyzed, comprising 159 cases without hepatic masses and 62 cases with hepatic masses. The model was trained and evaluated using two separate datasets: one containing cases without hepatic masses (Experiment 1) and the other combining cases with and without hepatic masses (Experiment 2).

Results

Both experiments demonstrated high segmentation performance, achieving mean Dice similarity coefficients of 0.926 (Experiment 1) and 0.929 (Experiment 2).

Discussion

The manual and predicted liver volumes showed excellent agreement, highlighting the potential clinical applicability of this approach.

Ultrasonographic features and blood biochemistry findings of cholangiocarcinoma in a captive polar bear (Ursus maritimus)
Keita Kakisaka; Nozomu Yokoyama; Fuka Takahashi; Keisuke Aoshima; Mitsuyoshi Takiguchi
Veterinary Record Case Reports, Wiley, 28 Jun. 2025, [Lead author], [International Magazine]
Scientific journal, ABSTRACT

A 29‐year‐old male captive polar bear (Ursus maritimus) with a year‐long history of elevated gamma‐glutamyl transpeptidase (GGT) presented with a 2‐week history of anorexia and abdominal distention. Blood biochemistry revealed a severely elevated GGT (>1500 IU/L). Abdominal ultrasound revealed multiple cystic hepatic masses and marked ascites. Fourteen days after initial presentation, the patient was found dead. Postmortem examination revealed hepatomegaly with diffuse, multifocal, coalescing cysts containing a red‒tan to dark‐red serous fluid. Histopathologically, the cyst walls were lined by flattened or cuboidal neoplastic cells, some exhibiting tubulopapillary projections into the lumen. Metastatic lesions were identified in the anterior mediastinal lymph nodes, lungs and kidneys. This case was diagnosed as cholangiocarcinoma. While there are numerous reports of cholangiocarcinoma in polar bears, published data on blood biochemistry and abdominal ultrasonographic findings are limited. This case report illustrates the benefit of blood biochemistry and abdominal ultrasound in investigating cholangiocarcinoma in polar bears.

Evaluation of the course of improvement with molnupiravir treatment for feline infectious peritonitis.
Shino Yoshida; Mei Sugawara-Suda; Kazuyoshi Sasaoka; Noboru Sasaki; Nozomu Yokoyama; Kensuke Nakamura; Keitaro Morishita; Sangho Kim; Takafumi Sunaga; Mitsuyoshi Takiguchi
The Canadian veterinary journal = La revue veterinaire canadienne, 66, 5, 546, 554, May 2025, [International Magazine]
English, Scientific journal, OBJECTIVE: To clarify the clinical course during molnupiravir treatment for feline infectious peritonitis (FIP). ANIMALS AND PROCEDURE: Cats diagnosed with FIP and treated with molnupiravir at Hokkaido University Veterinary Teaching Hospital (Sapporo, Hokkaido, Japan) were retrospectively reviewed. RESULTS: Eleven cats were eligible for inclusion. Six cats had effusive FIP and 5 had non-effusive FIP. In noneffusive cases, 2 cats had neurological abnormalities at diagnosis, whereas 1 additional cat developed neurological signs during treatment. The median initial dosage of molnupiravir was 13.0 mg/kg (range: 10.0 to 15.0 mg/kg), PO, q12h. One cat died after 11 d and the remaining 10 cats completed an 84-day course of treatment. All neurological cases were given dosage increases, extended treatment duration, or both. The median final dosage of molnupiravir in non-neuro-FIP cases was 13.1 mg/kg (range: 10.0 to 15.0 mg/kg), PO, q12h, whereas dosages in neuro-FIP cases were 15.0, 15.2, and 17.2 mg/kg, PO, q12h in the 3 affected cats, respectively. In non-neurological cases, dysrexia, lethargy, and high serum amyloid A were resolved within 15 d. Total follow-up duration ranged from 175 to 362 d. No relapses were observed. CONCLUSION AND CLINICAL RELEVANCE: Monitoring responses to molnupiravir treatment requires observing clinical signs and conducting clinicopathological evaluations, including acute-phase protein evaluation.

Prospective Estimation of the Prevalence of Thromboembolism in Dogs With Inflammatory Protein-Losing Enteropathy
Nene Oishi; Hiroshi Ohta; Masahiro Tamura; Kiwamu Hanazono; Kenjiro Miyoshi; Nozomu Yokoyama; Genya Shinbo
Journal of Veterinary Internal Medicine, 01 May 2025
Scientific journal

Case report: Echinococcus multilocularis infection in a dog showing gastrointestinal signs in Hokkaido, Japan
Izumi Kida; Naoki Hayashi; Nozomu Yokoyama; Noriyuki Nagata; Kazuyoshi Sasaoka; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hirokazu Kouguchi; Kinpei Yagi; Ryo Nakao; Mitsuyoshi Takiguchi; Nariaki Nonaka
Frontiers in Veterinary Science, 11, Frontiers Media SA, 13 Jun. 2024, [Corresponding author]
Scientific journal, Echinococcus multilocularis is a cestode that causes human alveolar echinococcosis, a lethal zoonotic disease distributed in the northern hemisphere. The life cycle of this parasite is maintained in nature by voles as intermediate hosts and foxes as definitive hosts in Hokkaido, Japan. Although dogs are also susceptible to the parasite, the infection has been considered typically asymptomatic. We report the detection of E. multilocularis eggs in the diarrheal feces of a dog with chronic gastrointestinal signs, which disappeared after anthelmintic treatment. The mitochondrial genome sequence constructed by sequencing of the overlapping PCRs using DNA from the eggs was identical to the most predominant haplotype previously reported in red foxes in Hokkaido. This case highlights that Echinococcus infection should be considered as a differential diagnosis for diarrheal dogs in the disease endemic areas. Further efforts are needed to accumulate parasite genotypes in domestic dogs as well as humans to assess the risk of human infection from dogs.

Antimicrobial resistance and self-reported hand hygiene awareness before and after an infection prevention and control programme: a 7-year analysis in a small animal veterinary teaching hospital
K. Sasaoka; T. Sato; K. Morishita; K. Hosoya; N. Yokoyama; T. Sato; M. Horiuchi; M. Takiguchi
The Veterinary Journal, 106154, 106154, Elsevier BV, May 2024
Scientific journal

A de novo nonsense variant in the DMD gene associated with X-linked dystrophin-deficient muscular dystrophy in a cat.
Nozomu Yokoyama; Yuki Matsumoto; Takahisa Yamaguchi; Kazuki Okada; Ryohei Kinoshita; Genya Shimbo; Hisashi Ukawa; Ryuga Ishii; Kensuke Nakamura; Jumpei Yamazaki; Mitsuyoshi Takiguchi
Journal of veterinary internal medicine, 13 Apr. 2024, [Lead author], [International Magazine]
English, Scientific journal

An inflammatory bowel disease-associated SNP increases local thyroglobulin expression to develop inflammation in miniature dachshunds
Yong Bin Teoh; Jing-Jing Jiang; Takeshi Yamasaki; Noriyuki Nagata; Toshiki Sugawara; Rie Hasebe; Hiroshi Ohta; Noboru Sasaki; Nozomu Yokoyama; Kensuke Nakamura; Yumiko Kagawa; Mitsuyoshi Takiguchi; Masaaki Murakami
Frontiers in Veterinary Science, 10, Frontiers Media SA, 14 Jul. 2023
Scientific journal

Successful treatment of sclerosing encapsulating peritonitis in a cat using bioresorbable hyaluronate-carboxymethylcellulose membrane after surgical adhesiolysis and long-term prednisolone
Nozomu Yokoyama; Ryohei Kinoshita; Hiroshi Ohta; Kazuki Okada; Genya Shimbo; Kazuyoshi Sasaoka; Noriyuki Nagata; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Yumiko Kagawa; Mitsuyoshi Takiguchi
Journal of Feline Medicine and Surgery Open Reports, 9, 2, Jul. 2023, [Lead author]
Scientific journal

Investigation of the therapeutic effects, predictors, and complications of long-term immunosuppressive therapy in dogs with precursor-targeted immune-mediated anemia.
Mei Sugawara-Suda; Keitaro Morishita; Yuto Iwanaga; Jumpei Yamazaki; Yumiko Kagawa; Nozomu Yokoyama; Noboru Sasaki; Hiroshi Ohta; Kensuke Nakamura; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 85, 7, 695, 701, 01 Jul. 2023, [Domestic magazines]
English, Scientific journal

Zoobiquity experiments show the importance of the local MMP9-plasminogen axis in inflammatory bowel diseases in both dogs and patients.
Takeshi Yamasaki; Noriyuki Nagata; Toru Atsumi; Rie Hasebe; Yuki Tanaka; Izuru Ohki; Shimpei Kubota; Yuta Shinohara; Yong Bin Teoh; Nozomu Yokoyama; Noboru Sasaki; Kensuke Nakamura; Hiroshi Ohta; Takehiko Katsurada; Yoshihiro Matsuno; Shintaro Hojyo; Shigeru Hashimoto; Mitsuyoshi Takiguchi; Masaaki Murakami
International immunology, 35, 7, 313, 326, 18 Mar. 2023, [International Magazine]
English, Scientific journal

Transcriptome and proteome analysis of dogs with precursor targeted immune-mediated anemia treated with splenectomy.
Mei Sugawara-Suda; Keitaro Morishita; Osamu Ichii; Takashi Namba; Keisuke Aoshima; Yumiko Kagawa; Sangho Kim; Kenji Hosoya; Nozomu Yokoyama; Noboru Sasaki; Kensuke Nakamura; Jumpei Yamazaki; Mitsuyoshi Takiguchi
PloS one, 18, 5, e0285415, 2023, [International Magazine]
English, Scientific journal

Biological effects related to exposure to polychlorinated biphenyl (PCB) and decabromodiphenyl ether (BDE-209) on cats
Khidkhan K; Mizukawa H; Ikenaka Y; Nakayama SMM; Nomiyama K; Yokoyama N; Ichii O; Takiguchi M; Tanabe S; Ishizuka M
PLOS ONE, 18, 1, e0277689, Jan. 2023, [International Magazine]
English, Scientific journal

An experimental challenge model for Leishmania donovani in beagle dogs, showing a similar pattern of parasite burden in the peripheral blood and liver.
Hiroya Konno; Nozomu Yokoyama; Yu Tamura; Keisuke Aoshima; Ryo Nakao; Mitsuyoshi Takiguchi; Ken Katakura
Parasitology research, 121, 12, 3569, 3579, 12 Oct. 2022, [International Magazine]
English, Scientific journal

Ureteral morphology and pathology during urolithiasis in cats.
Osamu Ichii; Kazuhisa Oyamada; Hazuki Mizukawa; Nozomu Yokoyama; Takashi Namba; Yuki Otani; Yaser Hosny Ali Elewa; Noboru Sasaki; Teppei Nakamura; Yasuhiro Kon
Research in veterinary science, 151, 10, 20, 11 Jul. 2022, [International Magazine]
English, Scientific journal

Health impact assessment of pet cats caused by organohalogen contaminants by serum metabolomics and thyroid hormone analysis.
Kei Nomiyama; Yasuo Yamamoto; Akifumi Eguchi; Hiroyuki Nishikawa; Hazuki Mizukawa; Nozomu Yokoyama; Osamu Ichii; Mitsuyoshi Takiguchi; Shouta M M Nakayama; Yoshinori Ikenaka; Mayumi Ishizuka
The Science of the total environment, 842, 156490, 156490, 03 Jun. 2022, [International Magazine]
English, Scientific journal

Urinary corticoid to creatinine ratios using IMMULITE 2000 XPi for diagnosis of canine hypercortisolism.
Noriyuki Nagata; Hiryu Sawamura; Keitaro Morishita; Kenji Hosoya; Nozomu Yokoyama; Kazuyoshi Sasaoka; Noboru Sasaki; Kensuke Nakamura; Yoshinori Ikenaka; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 84, 7, 954, 959, 27 May 2022, [Domestic magazines]
English, Scientific journal

Characterization of mucin gene expression and goblet cell proportion in inflammatory colorectal polyps in miniature dachshunds.
Noriyuki Nagata; Hiroshi Ohta; Nozomu Yokoyama; Yong Bin Teoh; Noboru Sasaki; Kensuke Nakamura; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 84, 6, 872, 876, 05 May 2022, [Domestic magazines]
English, Scientific journal

Assessment of changes in blood pancreatic lipase activities using FDC-v-LIP in dogs that underwent various surgical procedures.
Kanna Saeki; Kohei Saeki; Nozomu Yokoyama; Koichi Ohno; Ryohei Nishimura
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 32, 4, 471, 478, 20 Apr. 2022, [International Magazine]
English, Scientific journal

Serum steroid profiling of hepatocellular carcinoma associated with hyperadrenocorticism in dogs: A preliminary study.
Thandar Oo; Noboru Sasaki; Yoshinori Ikenaka; Takahiro Ichise; Noriyuki Nagata; Nozomu Yokoyama; Kazuyoshi Sasaoka; Keitaro Morishita; Kensuke Nakamura; Mitsuyoshi Takiguchi
Frontiers in veterinary science, 9, 1014792, 1014792, 2022, [International Magazine]
English, Scientific journal

Evaluation of the central lymphatic vessel size using non-contrast-enhanced magnetic resonance lymphography in dogs with intestinal lymphangiectasia
Takuro Nagahara; Koichi Ohno; Itsuma Nagao; Taisuke Nakagawa; Nozomu Yokoyama; Kie Yamamoto; Reina Fujiwara; Yuko Goto-Koshino; James K. Chambers; Kazuyuki Uchida; Yasuyuki Momoi; Hirotaka Tomiyasu; Hajime Tsujimoto
Japanese Journal of Veterinary Research, 70, 2, 57, 63, 2022
Scientific journal

Simultaneous steroids measurement in dogs with hyperadrenocorticism using a column-switching liquid chromatography-tandem mass spectrometry method.
Noboru Sasaki; Thandar Oo; Yoshikazu Yasuda; Takahiro Ichise; Noriyuki Nagata; Nozomu Yokoyama; Kazuyoshi Sasaoka; Keitaro Morishita; Shouta Mm Nakayama; Mayumi Ishizuka; Kensuke Nakamura; Mitsuyoshi Takiguchi; Yoshinori Ikenaka
The Journal of veterinary medical science, 83, 11, 1634, 1642, 17 Sep. 2021, [Domestic magazines]
English, Scientific journal

Changes in the coagulation parameters in dogs with protein-losing enteropathy between before and after treatment.
Takuro Nagahara; Koichi Ohno; Itsuma Nagao; Taisuke Nakagawa; Nozomu Yokoyama; Aki Ohmi; Yuko Goto-Koshino; James K Chambers; Kazuyuki Uchida; Hirotaka Tomiyasu; Hajime Tsujimoto
The Journal of veterinary medical science, 83, 8, 1295, 1302, 26 Aug. 2021, [Domestic magazines]
English, Scientific journal

Prognostic value of small intestinal dilatation in dogs with protein-losing enteropathy.
Hiroshi Ohta; Noriyuki Nagata; Nozomu Yokoyama; Tatsuyuki Osuga; Noboru Sasaki; Keitaro Morishita; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 83, 3, 378, 384, 11 Mar. 2021, [Domestic magazines]
English

Gene expression of leucine-rich alpha-2 glycoprotein in the polypoid lesion of inflammatory colorectal polyps in miniature dachshunds.
Hiroshi Ohta; Yu Tamura; Nozomu Yokoyama; Noriyuki Nagata; Tatsuyuki Osuga; Noboru Sasaki; Yumiko Kagawa; Keitaro Morishita; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 82, 10, 1445, 1449, 05 Aug. 2020, [Domestic magazines]
English, Scientific journal

An area ratio of thyroid gland to common carotid artery for evaluating the thyroid gland size.
Noboru Sasaki; Noriyuki Nagata; Keitaro Morishita; Tatsuyuki Osuga; Kazuyoshi Sasaoka; Nozomu Yokoyama; Hiroshi Ohta; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 82, 7, 1012, 1016, 31 Jul. 2020, [Domestic magazines]
English, Scientific journal

Altered hepatic cytochrome P450 expression in cats after chronic exposure to decabromodiphenyl ether (BDE-209).
Kraisiri Khidkhan; Hazuki Mizukawa; Yoshinori Ikenaka; Shouta M M Nakayama; Kei Nomiyama; Nozomu Yokoyama; Osamu Ichii; Mitsuyoshi Takiguchi; Shinsuke Tanabe; Mayumi Ishizuka
The Journal of veterinary medical science, 82, 7, 978, 982, 31 Jul. 2020, [Domestic magazines]
English, Scientific journal

Genome-wide DNA methylation analysis in canine gastrointestinal lymphoma.
Hiroshi Ohta; Jumpei Yamazaki; Jaroslav Jelinek; Teita Ishizaki; Yumiko Kagawa; Nozomu Yokoyama; Noriyuki Nagata; Noboru Sasaki; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 82, 5, 632, 638, 20 May 2020, [Domestic magazines]
English, Scientific journal

Comparison of the efficacy of cyclosporine and leflunomide in treating inflammatory colorectal polyps in miniature dachshunds
Akiyoshi Tani; Taisuke Seno; Nozomu Yokoyama; Taisuke Nakagawa; Hirotaka Tomiyasu; Yuko Goto-Koshino; Hajime Tsujimoto; Koichi Ohno
JOURNAL OF VETERINARY MEDICAL SCIENCE, 82, 4, 437, 440, Apr. 2020, [Domestic magazines]
English

Long interspersed nucleotide element-1 hypomethylation in canine malignant mucosal melanoma.
Teita Ishizaki; Jumpei Yamazaki; Shinji Meagawa; Nozomu Yokoyama; Keisuke Aoshima; Mitsuyoshi Takiguchi; Takashi Kimura
Veterinary and comparative oncology, 18, 4, 854, 860, 18 Mar. 2020, [International Magazine]
English, Scientific journal

Clinical characteristics of dogs with food-responsive protein-losing enteropathy.
Noriyuki Nagata; Hiroshi Ohta; Nozomu Yokoyama; Yong Bin Teoh; Khoirun Nisa; Noboru Sasaki; Tatsuyuki Osuga; Keitaro Morishita; Mitsuyoshi Takiguchi
Journal of veterinary internal medicine, 34, 2, 659, 668, Mar. 2020, [International Magazine]
English, Scientific journal

Tissue distribution and characterization of feline cytochrome P450 genes related to polychlorinated biphenyl exposure.
Kraisiri Khidkhan; Hazuki Mizukawa; Yoshinori Ikenaka; Shouta M M Nakayama; Kei Nomiyama; Nozomu Yokoyama; Osamu Ichii; Wageh Sobhy Darwish; Mitsuyoshi Takiguchi; Shinsuke Tanabe; Mayumi Ishizuka
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 226, 108613, 108613, Dec. 2019, [International Magazine]
English, Scientific journal

Variations in ATP7B in cats with primary copper-associated hepatopathy.
Hajime Asada; James K Chambers; Mari Kojima; Yuko Goto-Koshino; Taisuke Nakagawa; Nozomu Yokoyama; Masaya Tsuboi; Kazuyuki Uchida; Hajime Tsujimoto; Koichi Ohno
Journal of feline medicine and surgery, 22, 8, 1098612X19884763, 759, 05 Nov. 2019, [International Magazine]
English, Scientific journal

Effects of PCB exposure on serum thyroid hormone levels in dogs and cats.
Kohki Takaguchi; Hiroyuki Nishikawa; Hazuki Mizukawa; Rumi Tanoue; Nozomu Yokoyama; Osamu Ichii; Mitsuyoshi Takiguchi; Shouta M M Nakayama; Yoshinori Ikenaka; Tatsuya Kunisue; Mayumi Ishizuka; Shinsuke Tanabe; Hisato Iwata; Kei Nomiyama
The Science of the total environment, 688, 1172, 1183, 20 Oct. 2019, [International Magazine]
English, Scientific journal

Sphingosine-1-phosphate (S1P) signaling regulates the production of intestinal IgA and its potential role in the pathogenesis of canine inflammatory bowel disease.
Maho Nakazawa; Shingo Maeda; Nozomu Yokoyama; Taisuke Nakagawa; Tomohiro Yonezawa; Koichi Ohno; Naoaki Matsuki
The Journal of veterinary medical science, 81, 9, 1249, 1258, 03 Sep. 2019, [Domestic magazines]
English, Scientific journal

Effect of ultra low fat diet on regulatory T cells of dogs with intestinal limphangiectasia secondary to chronic enteropathy: A pilot study
Khoirun Nisa; Hiroshi Ohta; Nozomu Yokoyama; Masahiro Tamura; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Rommaneeya Leela-Arporn; Tomoya Morita; Tatsuyuki Osuga; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Yumiko Kagawa; Mitsuyoshi Takiguchi
JAPANESE JOURNAL OF VETERINARY RESEARCH, 67, 3, 221, 227, Aug. 2019
English, Scientific journal

Renal Infiltration of Macrophages in Canine and Feline Chronic Kidney Disease.
Y Ohara; A Yabuki; R Nakamura; O Ichii; H Mizukawa; N Yokoyama; O Yamato
Journal of comparative pathology, 170, 53, 59, Jul. 2019, [International Magazine]
English, Scientific journal

Duodenal expression of antimicrobial peptides in dogs with idiopathic inflammatory bowel disease and intestinal lymphoma.
M Nakazawa; S Maeda; M Omori; K Kaji; N Yokoyama; T Nakagawa; J K Chambers; K Uchida; K Ohno; T Yonezawa; N Matsuki
Veterinary journal (London, England : 1997), 249, 47, 52, Jul. 2019, [International Magazine]
English, Scientific journal

Evaluation of duodenal perfusion by contrast-enhanced ultrasonography in dogs with chronic inflammatory enteropathy and intestinal lymphoma.
Khoirun Nisa; Sue Yee Lim; Masayoshi Shinohara; Tatsuyuki Osuga; Nozomu Yokoyama; Masahiro Tamura; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Rommaneeya Leela-Arporn; Tomoya Morita; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hiroshi Ohta; Mitsuyoshi Takiguchi
Journal of veterinary internal medicine, 33, 2, 559, 568, Mar. 2019, [International Magazine]
English, Scientific journal

Hepatic copper accumulation in a young cat with familial variations in the ATP7B gene.
Hajime Asada; Mari Kojima; Takuro Nagahara; Yuko Goto-Koshino; James K Chambers; Taisuke Nakagawa; Nozomu Yokoyama; Kazuyuki Uchida; Hajime Tsujimoto; Koichi Ohno
Journal of veterinary internal medicine, 33, 2, 874, 878, Mar. 2019, [International Magazine]
English, Scientific journal

Clinical features and prognosis of canine megaesophagus in Japan
Taisuke Nakagawa; Akihiro Doi; Koichi Ohno; Nozomu Yokoyama; Hajime Tsujimoto
JOURNAL OF VETERINARY MEDICAL SCIENCE, 81, 3, 348, 352, Mar. 2019
English, Scientific journal

Evaluation of visceral fat mass in dogs by computed tomography
Itsuma Nagao; Koichi Ohno; Takuro Nagahara; Nozomu Yokoyama; Taisuke Nakagawa; Reina Fujiwara; Kie Yamamoto; Yuko Goto-Koshino; Hirotaka Tomiyasu; Hajime Tsujimoto
Journal of Veterinary Medical Science, 81, 11, 1552, 1557, 2019
Scientific journal

Effect of acute volume overload on echocardiographic indices of right ventricular function and dyssynchrony assessed by use of speckle tracking echocardiography in healthy dogs.
Tomoya Morita; Kensuke Nakamura; Tatsuyuki Osuga; Nozomu Yokoyama; Keitaro Morishita; Noboru Sasaki; Hiroshi Ohta; Mitsuyoshi Takiguchi
American journal of veterinary research, 80, 1, 51, 60, Jan. 2019, [International Magazine]
English, Scientific journal

Effects of immunosuppressive prednisolone therapy on pancreatic tissue and concentration of canine pancreatic lipase immunoreactivity in healthy dogs
Hiroshi Ohta; Kazuki Kojima; Nozomu Yokoyama; Noboru Sasaki; Yumiko Kagawa; Kiwamu Hanazono; Tomohito Ishizuka; Keitaro Morishita; Kensuke Nakamura; Satoshi Takagi; Mitsuyoshi Takiguchi
CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE, 82, 4, 278, 286, Oct. 2018, [International Magazine]
English, Scientific journal

Changes in Renal Peritubular Capillaries in Canine and Feline Chronic Kidney Disease
R. Nakamura; A. Yabuki; O. Ichii; H. Mizukawa; N. Yokoyama; O. Yamato
Journal of Comparative Pathology, 160, 79, 83, W.B. Saunders Ltd, 01 Apr. 2018
English, Scientific journal

The effect of sedation with a combination of butorphanol and midazolam on quantitative contrast-enhanced ultrasonography of duodenum in healthy dogs.
Khoirun Nisa; Sue Yee Lim; Tatsuyuki Osuga; Nozomu Yokoyama; Masahiro Tamura; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Rommaneeya Leela-Arporn; Tomoya Morita; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hiroshi Ohta; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 80, 3, 453, 459, 24 Mar. 2018, [Domestic magazines]
English, Scientific journal

Transcranial Doppler Ultrasound Examination in Dogs with Suspected Intracranial Hypertension Caused by Neurologic Diseases
K. Sasaoka; K. Nakamura; T. Osuga; T. Morita; N. Yokoyama; K. Morishita; N. Sasaki; H. Ohta; M. Takiguchi
Journal of Veterinary Internal Medicine, 32, 1, 314, 323, Blackwell Publishing Inc., 01 Jan. 2018
English, Scientific journal

Repeatability and reproducibility of quantitative contrast-enhanced ultrasonography for assessing duodenal perfusion in healthy dogs.
Khoirun Nisa; Sue Yee Lim; Masayoshi Shinohara; Noriyuki Nagata; Kazuyoshi Sasaoka; Angkhana Dermlim; Rommaneeya Leela-Arporn; Tomoya Morita; Nozomu Yokoyama; Tatsuyuki Osuga; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Hiroshi Ohta; Mitsuyoshi Takiguchi
The Journal of veterinary medical science, 79, 9, 1585, 1590, 29 Sep. 2017, [Domestic magazines]
English, Scientific journal

The repeatability and characteristics of right ventricular longitudinal strain imaging by speckle-tracking echocardiography in healthy dogs
T. Morita; K. Nakamura; T. Osuga; N. Yokoyama; N. Khoirun; K. Morishita; N. Sasaki; H. Ohta; M. Takiguchi
JOURNAL OF VETERINARY CARDIOLOGY, 19, 4, 351, 362, Aug. 2017
English, Scientific journal

Changes in right ventricular function assessed by echocardiography in dog models of mild RV pressure overload
Tomoya Morita; Kensuke Nakamura; Tatsuyuki Osuga; Nozomu Yokoyama; Keitaro Morishita; Noboru Sasaki; Hiroshi Ohta; Mitsuyoshi Takiguchi
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 34, 7, 1040, 1049, Jul. 2017
English, Scientific journal

Serial measurement of pancreatic lipase immunoreactivity concentration in dogs with immune-mediated disease treated with prednisolone
H. Ohta; T. Morita; N. Yokoyama; T. Osuga; N. Sasaki; K. Morishita; K. Nakamura; M. Takiguchi
JOURNAL OF SMALL ANIMAL PRACTICE, 58, 6, 342, 347, Jun. 2017
English, Scientific journal

Stimulation of colorectal biopsies from miniature dachshunds with inflammatory colorectal polyps with toll-like receptor ligands: A pilot study
Nozomu Yokoyama; Hiroshi Ohta; Yumiko Kagawa; Noriyuki Nagata; Khoirun Nisa; Tomoya Morita; Tatsuyuki Osuga; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Mitsuyoshi Takiguchi
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 188, 78, 83, Jun. 2017, [Lead author]
English, Scientific journal

Expression of apical junction complex proteins in colorectal mucosa of miniature dachshunds with inflammatory colorectal polyps
Nozomu Yokoyama; Hiroshi Ohta; Yumiko Kagawa; Rommaneeya Leela-Arporn; Angkhana Dermlim; Khoirun Nisa; Tomoya Morita; Tatsuyuki Osuga; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Mitsuyoshi Takiguchii
JOURNAL OF VETERINARY MEDICAL SCIENCE, 79, 3, 456, 463, Mar. 2017, [Lead author]
English, Scientific journal

Localization of Toll-like Receptor (TLR) 2 and TLR4 mRNA in the Colorectal Mucosa of Miniature Dachshunds with Inflammatory Colorectal Polyps
N. Yokoyama; H. Ohta; J. Yamazaki; Y. Kagawa; O. Ichii; N. Khoirun; T. Morita; T. Osuga; S. Y. Lim; N. Sasaki; K. Morishita; K. Nakamura; M. Takiguchi
JOURNAL OF COMPARATIVE PATHOLOGY, 156, 2-3, 183, 190, Feb. 2017, [Lead author]
English, Scientific journal

Effects of experimental cardiac volume loading on left atrial phasic function in healthy dogs
Tatsuyuki Osuga; Kensuke Nakamura; Tomoya Morita; Khoirun Nisa; Nozomu Yokoyama; Noboru Sasaki; Keitaro Morishita; Hiroshi Ohta; Mitsuyoshi Takiguchi
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77, 9, 952, 960, Sep. 2016
English, Scientific journal

Repeatability and reproducibility of right ventricular Tei index valves derived from three echocardiographic methods for evaluation of cardiac function in dogs
Tomoya Morita; Kensuke Nakamura; Tatsuyuki Osuga; Sue Yee Lim; Nozomu Yokoyama; Keitaro Morishita; Hiroshi Ohta; Mitsuyoshi Takiguchi
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77, 7, 715, 720, Jul. 2016
English, Scientific journal

Vitamin D Status in Different Stages of Disease Severity in Dogs with Chronic Valvular Heart Disease
T. Osuga; K. Nakamura; T. Morita; S. Y. Lim; K. Nisa; N. Yokoyama; N. Sasaki; K. Morishita; H. Ohta; M. Takiguchi
JOURNAL OF VETERINARY INTERNAL MEDICINE, 29, 6, 1518, 1523, Nov. 2015
English, Scientific journal

Effects of various cardiovascular drugs on indices obtained with two-dimensional speckle tracking echocardiography of the left atrium and time-left atrial area curve analysis in healthy dogs
Tatsuyuki Osuga; Kensuke Nakamura; Tomoya Morita; Sue Yee Lim; Nozomu Yokoyama; Keitaro Morishita; Hiroshi Ohta; Mitsuyoshi Takiguchi
AMERICAN JOURNAL OF VETERINARY RESEARCH, 76, 8, 702, 709, Aug. 2015
English, Scientific journal

Quantitative Contrast-enhanced Ultrasonographic Assessment of Naturally Occurring Pancreatitis in Dogs
S. Y. Lim; K. Nakamura; K. Morishita; N. Sasaki; M. Murakami; T. Osuga; N. Yokoyama; H. Ohta; M. Yamasaki; M. Takiguchi
JOURNAL OF VETERINARY INTERNAL MEDICINE, 29, 1, 71, 78, Jan. 2015
English, Scientific journal

Prognostic Value of Left Atrial Function in Dogs with Chronic Mitral Valvular Heart Disease
K. Nakamura; T. Osuga; K. Morishita; S. Suzuki; T. Morita; N. Yokoyama; H. Ohta; M. Yamasaki; M. Takiguchi
JOURNAL OF VETERINARY INTERNAL MEDICINE, 28, 6, 1746, 1752, Nov. 2014
English, Scientific journal

Evaluation of Selected Cytokine Gene Expression in Colonic Mucosa from Dogs with Idiopathic Lymphocytic-plasmacytic Colitis
Yu Tamura; Hiroshi Ohta; Nozomu Yokoyama; Sue Yee Lim; Tatsuyuki Osuga; Keitaro Morishita; Kensuke Nakamura; Masahiro Yamasaki; Mitsuyoshi Takiguchi
JOURNAL OF VETERINARY MEDICAL SCIENCE, 76, 10, 1407, 1410, Oct. 2014
English

In vitro and in vivo safety and efficacy Studies of amphotericin B on Babesia gibsoni
Masahiro Yamasaki; Eriko Harada; Yu Tamura; Sue Yee Lim; Tatsuyuki Ohsuga; Nozomu Yokoyama; Keitaro Morishita; Kensuke Nakamura; Hiroshi Ohta; Mitsuyoshi Takiguchi
VETERINARY PARASITOLOGY, 205, 3-4, 424, 433, Oct. 2014
English, Scientific journal

Case report: Protein-losing enteropathy caused by Mesocestoides vogae (syn. M. corti) in a dog
Yu Tamura; Hiroshi Ohta; Takuya Kashiide; Jun Matsumoto; Tatsuya Sakurai; Nozomu Yokoyama; Keitaro Morishita; Kensuke Nakamura; Masahiro Yamasaki; Mitsuyoshi Takiguchi
VETERINARY PARASITOLOGY, 205, 1-2, 412, 415, Sep. 2014
English, Scientific journal

Expression of apical junction complex proteins in duodenal mucosa of dogs with inflammatory bowel disease
Hiroshi Ohta; Yuji Sunden; Nozomu Yokoyama; Tatsuyuki Osuga; Sue Yee Lim; Yu Tamura; Keitaro Morishita; Kensuke Nakamura; Masahiro Yamasaki; Mitsuyoshi Takiguchi
AMERICAN JOURNAL OF VETERINARY RESEARCH, 75, 8, 746, 751, Aug. 2014
English, Scientific journal

Markedly increased expression of interleukin-8 in the colorectal mucosa of inflammatory colorectal polyps in miniature dachshunds
Yu Tamura; Hiroshi Ohta; Shidow Torisu; Masashi Yuki; Nozomu Yokoyama; Masahiro Murakami; Sue Yee Lim; Tatsuyuki Osuga; Keitaro Morishita; Kensuke Nakamura; Masahiro Yamasaki; Mitsuyoshi Takiguchi
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 156, 1-2, 32, 42, Nov. 2013
English, Scientific journal

Expression of CD4(+) T cell cytokine genes in the colorectal mucosa of inflammatory colorectal polyps in miniature dachshunds
Hiroshi Ohta; Kanae Takada; Shidow Torisu; Masashi Yuki; Yu Tamura; Nozomu Yokoyama; Tatsuyuki Osuga; Sue Yee Lim; Masahiro Murakami; Noboru Sasaki; Kensuke Nakamura; Masahiro Yamasaki; Mitsuyoshi Takiguchi
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 155, 4, 259, 263, Oct. 2013
English, Scientific journal

科目別 診断推論 消化器 二次プロブレムからの診断推論 第12回 腹部超音波検査:胆嚢粘液嚢腫を疑ったとき
山本集士, 横山 望, Small Animal Internal Medicine, 3, 1, 2026

科目別 診断推論 消化器 二次プロブレムからの診断推論 第11回 腹部超音波検査:消化管腫瘤を認めたとき
菅原芽伊, 横山 望, Small Animal Internal Medicine, 2, 6, 2025

銅と肝臓 肝臓組織中銅濃度測定(ICP-MS)
横山望; 池中良徳, GO-VET, 9, 1, 2025

科目別 診断推論 消化器 二次プロブレムからの診断推論(第10回)腹部超音波検査 : 肝臓の多発性結節/腫瘤を認めたとき
立野 守洋; 横山 望, Small animal internal medicine, 2, 5, 76, 83, 2025
町田 : エデュワードプレス = EDUWARD Press, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第8回)X線検査 : 小腸内異物
須田 光紫; 横山 望, Small animal internal medicine, 2, 3, 62, 73, 2025
町田 : エデュワードプレス = EDUWARD Press, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第9回)腹部超音波検査 : 肝臓の孤立性結節/腫瘤を認めたとき
立野 守洋; 横山 望, Small animal internal medicine, 2, 4, 84, 91, 2025
町田 : エデュワードプレス = EDUWARD Press, Japanese

総合臨床医を育てる全科ラウンド 第3回 消化器〈1〉口~食道〈D〉巨大食道症vs食道アカラシア様症候群
横山望, Veterinary Board, 7, 9, 112, 122, 2025
(株)エデュワードプレス, Japanese

総合臨床医を育てる全科ラウンド 第3回 消化器〈1〉口~食道〈C〉輪状咽頭アカラシアvs咽頭機能不全
横山望, Veterinary Board, 7, 9, 100, 110, 2025
(株)エデュワードプレス, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第6回 1)X線検査 : 標準的な検査方法
新坊 弦也; 横山 望, Small animal internal medicine, 2, 1, 62, 67, 2025
町田 : エデュワードプレス = EDUWARD Press, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第7回)X線検査 : 胃内異物
山本 集士; 横山 望, Small animal internal medicine, 2, 2, 64, 72, 2025
町田 : エデュワードプレス = EDUWARD Press, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第6回 2)巨大食道症を認めたとき
阪本 恵美; 横山 望, Small animal internal medicine, 2, 1, 68, 75, 2025
町田 : エデュワードプレス = EDUWARD Press, Japanese

超音波検査から覗く腸管の病態~炎症と腫瘍~第4回 消化器型リンパ腫
横山望, Veterinary Immunology for Practitioners, 10, 1, 16, 21, Jan. 2025
相模原 : 理研ベンチャー動物アレルギー検査, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第2回) 血液検査 リパーゼ値の上昇
川上 侑記; 横山 望, Small Animal Internal Medicine, 1, 2, 79, 87, Jun. 2024
(株)エデュワードプレス, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第1回) 血液検査 急性の肝酵素値の上昇
塩原 希; 横山 望, Small Animal Internal Medicine, 1, 1, 70, 81, Apr. 2024
(株)エデュワードプレス, Japanese

悩ましい胆嚢炎の診断と胆石症の対応 画像検査:X線検査と腹部超音波検査
横山望, GO-VET, 8, 1, 2024

科目別 診断推論 消化器 二次プロブレムからの診断推論(第4回)血液検査 : 総胆汁酸とアンモニア値の上昇
阪本 恵美; 横山 望, Small animal internal medicine, 1, 4, 33, 43, 2024
町田 : エデュワードプレス = EDUWARD Press, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第5回)糞便検査の標準的アプローチと内部寄生虫の探索
須田 光紫; 横山 望, Small animal internal medicine, 1, 5, 80, 91, 2024
町田 : エデュワードプレス = EDUWARD Press, Japanese

超音波検査から覗く腸管の病態~炎症と腫瘍~第3回 猫消化管好酸球性硬化性線維増殖症
横山望, Veterinary Immunology for Practitioners, 9, 4, 24, 29, 2024
相模原 : 理研ベンチャー動物アレルギー検査, Japanese

科目別 診断推論 消化器 二次プロブレムからの診断推論(第3回)血液検査 : 慢性の肝酵素値の上昇
阪本 裕美; 横山 望, Small animal internal medicine, 1, 3, 65, 75, 2024
町田 : エデュワードプレス = EDUWARD Press, Japanese

超音波検査から覗く腸管の病態~炎症と腫瘍~第2回 犬の慢性腸症
横山望, Veterinary Immunology for Practitioners, 9, 3, 22, 28, 2024
動物アレルギー検査(株), Japanese

超音波検査から覗く腸管の病態~炎症と腫瘍~第1回 腸管の超音波検査の基礎
横山望, Veterinary Immunology for Practitioners, 9, 2, 2024

【エビデンスの有無にフォーカス 肝・胆・膵の薬】(第1章)肝臓・胆嚢の薬剤 メトロニダゾール
横山 望, SA Medicine, 25, 2, 16, 19, Apr. 2023
(株)エデュワードプレス, Japanese

【エビデンスの有無にフォーカス 肝・胆・膵の薬】(第2章)膵臓の薬剤 パンクレアチン
横山 望, SA Medicine, 25, 2, 38, 40, Apr. 2023
(株)エデュワードプレス, Japanese

画像所見からみる診断のアプローチ 胃・小腸の拡張
横山望, 伴侶動物画像診断, 8, 2, 6, 32, Apr. 2023
緑書房, Japanese

トクシュウ モンミャクタイ ジュンカン シャント : ゲカ ト ナイカ ノ センタクシ : VETERINARY BOARD × CLINIC NOTE コラボ トクシュウ ダイ5ダン
横山 望, Veterinary board : 臨床の選択肢を広げるケーススタディ・マガジン, 5, 1, 8, 18, Jan. 2023
インターズー, Japanese

トクシュウ モンミャクタイ ジュンカン シャント : ゲカ ト ナイカ ノ センタクシ : VETERINARY BOARD × CLINIC NOTE コラボ トクシュウ ダイ5ダン
横山 望, Veterinary Board, 5, 1, 8, 18, Jan. 2023
(株)エデュワードプレス, Japanese

トクシュウ マンセイ チョウショウ : 「 オウト 、 ゲリ 、 ショクヨク ガ ナイ 」 ニ タイスル チリョウ ノ センタクシ : VETERINARY BOARD × CLINIC NOTE コラボ トクシュウ ダイ3ダン
横山 望, Veterinary board : 臨床の選択肢を広げるケーススタディ・マガジン, 4, 11, 66, 72, Nov. 2022
インターズー, Japanese

【慢性腸症～「嘔吐、下痢、食欲がない」に対する治療の選択肢～】(症例報告8)治療抵抗性腸症の猫の一例
横山 望, Veterinary Board, 4, 11, 66, 72, Nov. 2022
(株)エデュワードプレス, Japanese

猫の超音波検査 パーフェクトアトラス(第28回)肝・胆道系疾患
横山 望, Clinic note : clinical daily treatment for the small animal practitioner, 18, 9, 91, 106, Sep. 2022
インターズー, Japanese

【二次診療に紹介する前に!見逃しやすいこんな異常・疾患】消化器疾患 胆嚢粘液嚢腫と黄疸
横山 望, CAP: Companion Animal Practice, 37, 7, 22, 26, Jul. 2022
(株)緑書房, Japanese

猫の超音波検査 パーフェクトアトラス(第24回)腹腔(腹膜腔)疾患
横山 望, Clinic note : clinical daily treatment for the small animal practitioner, 18, 5, 49, 57, May 2022
(株)エデュワードプレス, Japanese

ACVIMコンセンサスステートメントから考える猫の膵炎 日本における猫の膵炎の症例報告
横山望, GO-VET, 5, 3, 2022

巨大食道症 巨大食道症の画像検査
横山望, GO-VET, 6, 1, 2022

低コレステロール血症は犬の膵外分泌不全を予測できるのか?
横山望; 大田寛; 永田矩之; 笹岡一慶; 新坊弦也; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜, 北海道獣医師会雑誌, 66, 8, 2022

オメプラゾールと胃酸分泌抑制薬—ピックアップ! 消化器系の薬
横山 望, SA medicine : 小動物内科専門誌, 28, 2, 16, 22, 2022
Japanese

スクラルファートと胃粘膜保護薬—ピックアップ! 消化器系の薬
横山 望, SA medicine : 小動物内科専門誌, 28, 2, 23, 27, 2022
エデュワードプレス, Japanese

猫の超音波検査パーフェクトアトラス 第20回 門脈疾患 食欲不振の猫
横山望, Clinic Note, 18, 1, 80, 93, 2022
(株)エデュワードプレス, Japanese

鑑別診断プラクティス~臨床医を育てる全科ラウンド~第2ラウンド 嘔吐
横山望, Clinic Note, 18, 3, 76, 85, 2022
インターズー, Japanese

猫の超音波検査 パーフェクトアトラス(第(12)回)大腸の腫瘍 症例 大腸性下痢の猫
横山 望, CLINIC NOTE, 17, 5, 54, 64, May 2021
(株)エデュワードプレス, Japanese

猫の超音波検査パーフェクトアトラス 第16回 小腸の腫瘍 症例 便秘の猫
横山望, Clinic Note, 17, 9, 2021

消化器疾患-3-犬の炎症性結直腸ポリープ
横山望, 伴侶動物治療指針, 12, 2021

What’s your diagnosis?第16回
横山望, GO-VET, 4, 4, 2021

猫の超音波検査パーフェクトアトラス(第8回) 胃の腫瘍 症例 慢性嘔吐の猫
横山 望, CLINIC NOTE, 17, 1, 108, 117, Jan. 2021
(株)エデュワードプレス, Japanese

ミニチュア・ダックスフンドの炎症性結直腸ポリープ 内科的治療
横山望, GO-VET, 4, 2, 2021

【リンパ腫2020 1冊で2度美味しい!リンパ腫を総復習+up date】解剖学的にみるリンパ腫 over viewとこの10年のup date 犬の消化器型リンパ腫
横山 望, Veterinary Oncology, 7, 4, 26, 32, Oct. 2020
(株)エデュワードプレス, Japanese

症例報告 銅関連性慢性肝炎の一例 (特集 犬の慢性肝炎 : ACVIMコンセンサス・ステートメントに基づく診断と治療)
横山 望, Veterinary board : 臨床の選択肢を広げるケーススタディ・マガジン, 2, 10, 15, 22, Oct. 2020
インターズー, Japanese

猫の超音波検査 パーフェクトアトラス(第4回)膵炎 症例 急性嘔吐と黄疸の猫
横山 望, Clinic note : journal of clinical daily treatment for small animals, 16, 9, 33, 44, Sep. 2020
インターズー, Japanese

隔月連載 ベーシック診療 消化管ケーススタディ(第12回)
横山 望, Clinic note : journal of clinical daily treatment for small animals, 16, 7, 74, 90, Jul. 2020
インターズー, Japanese

ベーシック診療 消化管ケーススタディ第12回 (CASE B)犬の抗菌薬反応性腸症と慢性大腸炎
横山 望, CLINIC NOTE, 16, 7, 81, 90, Jul. 2020
(株)エデュワードプレス, Japanese

症例報告 消化器毒性 : 大細胞性胃腸管型リンパ腫から考える対処法 (特集 これだけは押さえておきたい抗がん薬治療による有害事象への対応(後編))
横山 望, Veterinary board : 臨床の選択肢を広げるケーススタディ・マガジン, 2, 4, 14, 21, Apr. 2020
インターズー, Japanese

慢性腸症-慢性下痢の隠れた原因を探る-各論1)食事反応性腸症
永田矩之; 横山望, Clinic Note, 16, 12, 2020

ベーシック診療 消化管ケーススタディ(第9回) (CASE A)犬のジアルジア感染症の一例
横山 望, CLINIC NOTE, 15, 12, 50, 55, Dec. 2019
(株)エデュワードプレス, Japanese

ベーシック診療 消化管ケーススタディ(第9回) (CASE B)犬の炎症性結直腸ポリープ
横山 望, CLINIC NOTE, 15, 12, 55, 63, Dec. 2019
(株)エデュワードプレス, Japanese

犬猫の腸内細菌の役目を考える 感染症に打ち克つためにできること IBDと腸内細菌
横山 望, 動物臨床医学会年次大会プロシーディング, 40回, 1, 223, 225, Nov. 2019
動物臨床医学会, Japanese

犬猫の腸内細菌の役目を考える 感染症に打ち克つためにできること IBDと腸内細菌
横山 望, 動物臨床医学会年次大会プロシーディング, 40回, 1, 223, 225, Nov. 2019
動物臨床医学会, Japanese

緩和ケアと終末期医療 消化管腫瘍
横山望, Veterinary Oncology, 6, 2, 32‐38, 25 Apr. 2019
Japanese

消化管腫瘍 (特集 緩和ケアと終末期医療 : 死にゆく動物に寄り添うために)
横山 望, Veterinary oncology : 小動物腫瘍科専門誌, 6, 2, 32, 38, Apr. 2019
インターズー, Japanese

ベーシック診療 消化管ケーススタディ(第6回)
横山 望, J-vet : jounral for veterinary practitioner, 32, 4, 90, 103, Apr. 2019
インターズー, Japanese

ベーシック診療 消化管ケーススタディ(第6回) (CASE A)食道裂孔ヘルニアの猫
横山 望, J-VET, 32, 4, 90, 95, Apr. 2019
(株)インターズー, Japanese

ベーシック診療 消化管ケーススタディ(第6回) (CASE B)胃腺癌の犬
横山 望, J-VET, 32, 4, 96, 103, Apr. 2019
(株)インターズー, Japanese

消化管内寄生虫と感染症 : 二次診療施設の立場から (特集 臨床徴候シリーズ(vol. 10)体重減少 : 食べるのに痩せる)
横山 望, J-vet : jounral for veterinary practitioner, 32, 3, 30, 37, Mar. 2019
インターズー, Japanese

Consider The Role of Intestinal Bacterial Flora in Dogs and Cats－ Prepare the Intestinal Environment and Win Infections －:4. Benefits and Use of Prebiotics in Dogs and Cats with Inflammatory Bowel Disease
YOKOYAMA Nozomu, Journal of Animal Clinical Medicine, 28, 1, 11, 12, 2019
Japanese Society of Clinical Veterinary Medicine, Japanese

【臨床徴候シリーズvol.8 吐出・嘔吐】吐く症例 胃の疾患を疑うときと内視鏡検査の適応
横山 望, J-VET, 32, 1, 26, 36, Jan. 2019
(株)インターズー, Japanese

胆嚢疾患まるわかり 画像診断
横山望, GO-VET, 2, 1, 4‐11, 20 Dec. 2018
Japanese

ベーシック診療 消化管ケーススタディ(第3回)胃内異物の犬・小腸内異物の猫
横山 望, J-vet : jounral for veterinary practitioner, 31, 10, 68, 76, Oct. 2018
インターズー, Japanese

こんな症例に出会ったら?とある診察室を覗いて学ぶアプローチ法(第17回) うちの猫、元気だけど体重が減ってきて…
横山 望, CAP: Companion Animal Practice, 33, 5, 86, 91, May 2018
(株)緑書房, Japanese

超低脂肪食で治療した犬慢性腸症18例の回顧的検討
横山望; 大田寛; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜, 北海道獣医師会雑誌, 59, 8, 394, 394, Aug. 2015
(公社)北海道獣医師会, Japanese

ミニチュア・ダックスフンドの炎症性結直腸ポリープ症例の結直腸粘膜におけるToll‐like receptor2,4の局在解析
横山望; 大田寛; 賀川由美子; 山崎淳平; 市居修; KHOIRUN Nisa; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜, 日本獣医学会学術集会講演要旨集, 158回, 402, 402, Aug. 2015
(公社)日本獣医学会, Japanese

ミニチュア・ダックスフンドの炎症性結直腸ポリープ症例の結直腸粘膜におけるclaudinの蛋白質発現解析
YOKOYAMA NOZOMU; OTA HIROSHI; MORITA TOMOYA; OSUGA TATSUYUKI; LIM SUE YEE; MORISHITA KEITARO; NAKAMURA KENSUKE; TAKIGUCHI MITSUYOSHI, 日本獣医学会学術集会講演要旨集, 157回, 491, 491, Aug. 2014
(公社)日本獣医学会, Japanese

犬胃癌10症例における超音波検査所見
YOKOYAMA NOZOMI; OTA HIROSHI; NAKAMURA KENSUKE; MORISHITA KEITARO; YAMASAKI MASAHIRO; TAKIGUCHI MITSUYOSHI, 獣医麻酔外科学雑誌, 45, Suppl.1, 261, 261, Jun. 2014
(一社)日本獣医麻酔外科学会, Japanese

慢性特発性偽性腸閉塞症が疑われた犬の1例
YOKOYAMA NOZOMU; OTA HIROSHI; HASHIBA KANO; MORISHITA KEITARO; NAKAMURA KENSUKE; YAMASAKI MASAHIRO; OCHIAI KENJI; TERAMOTO HIDESHI; TAKIGUCHI MITSUYOSHI, 動物臨床医学会年次大会プロシーディング, 34回, 2, 59, 60, Nov. 2013
動物臨床医学会, Japanese

両側性子宮分節性無形成から片側性子宮角捻転に至った犬の1例
YOKOYAMA NOZOMI; NAKAMURA KENSUKE; KIMURA TAKASHI; OTA HIROSHI; YAMASAKI MASAHIRO; TAKIGUCHI MITSUYOSHI, 北海道獣医師会雑誌, 56, 8, 418, 418, Aug. 2012
(公社)北海道獣医師会, Japanese

アルゴリズムでよみとく獣医師のための鑑別診断プラクティス
大森, 啓太郎
EDUWARD Press, Jun. 2024, 9784866712239, 317p, Japanese, [Contributor]

猫の超音波検査 : 描出から診断・治療まで
中村, 健介
EDUWARD Press, May 2024, 9784866712215, 415p, Japanese, [Joint work]

腹部
滝口, 満喜; 中村, 健介; 横山, 望; 新坊, 弦也
学窓社, Jul. 2023, 9784873627892, 151p, Japanese

犬と猫の救急診療ファーストコンタクト : 最初の5分と60分にすべき初期対応
望月, 学
緑書房, Jun. 2023, 9784895318822, 223p, Japanese

腹部
滝口, 満喜; 中村, 健介; 横山, 望
学窓社, Mar. 2022, 9784873627823, 205p, Japanese

とある臨床現場を覗いて学ぶ犬と猫の初期診療アプローチ
鳩谷, 晋吾
緑書房, Oct. 2021, 9784895317603, 255p, Japanese

伴侶動物治療指針 : 臓器・疾患別最新の治療法33
石田, 卓夫
緑書房, Oct. 2021, 9784895317597, 426p, Japanese

犬と猫の消化管 : ベーシック診療
大野, 耕一
EDUWARD Press, Jun. 2021, 9784866711539, x, 393p, Japanese

犬の内科診療
石田, 卓夫
緑書房, Mar. 2021, 9784895315852, 503p, Japanese

猫の治療ガイド : 私はこうしている
辻本, 元; 小山, 秀一; 大草, 潔; 中村, 篤史
Eduward press, Aug. 2020, 9784866711225, xvi, 963, 23p, Japanese

犬の治療ガイド : 私はこうしている
辻本, 元; 小山, 秀一; 大草, 潔; 中村, 篤史
Eduward press, Aug. 2020, 9784866711218, xvi, 1219, 28p, Japanese

猫の総胆管閉塞：内科医の立場から
横山 望
第22回日本獣医内科学アカデミー学術大会, 21 Feb. 2026, Japanese, Invited oral presentation
20 Feb. 2026 - 22 Feb. 2026, [Invited]

愛玩動物看護師が介入できる消化器科
横山 望
第22回日本獣医内科学アカデミー学術大会, 20 Feb. 2026, Japanese, Invited oral presentation
20 Feb. 2026 - 22 Feb. 2026, [Invited]

消化器企画 継承！胃腸疾患の検査（内視鏡・超音波）
滝口満喜; 亘 敏広; 坂井学; 阪本裕美; 横山 望
第22回日本獣医内科学アカデミー学術大会, 21 Feb. 2026, Japanese, Nominated symposium
19 Feb. 2026 - 21 Feb. 2026, [Invited]

Cholecystitis and Cholelithiasis: What is your medical management? Grumbles from veterinary internists – Decision making, including imaging findings and medical treatments –
横山 望
第46回 動物臨床医学会, 19 Oct. 2025, Japanese, Nominated symposium
18 Oct. 2025 - 19 Oct. 2025, [Invited]

Feline diarrhea - Diagnosis and Treatment for Different Ages -
横山 望
第46回 動物臨床医学会, 18 Oct. 2025, Japanese, Public discourse
18 Oct. 2025 - 19 Oct. 2025, [Invited]

内視鏡の適応と基本・ 異物取りのコツ
横山 望
第21回日本獣医内科学アカデミー学術大会, 15 Feb. 2025, Japanese, Public discourse
14 Feb. 2025 - 16 Feb. 2025, [Invited]

肝生検の適応と禁忌
横山 望
第21回日本獣医内科学アカデミー学術大会, 15 Feb. 2025, Japanese, Public discourse
14 Feb. 2025 - 16 Feb. 2025, [Invited]

学び直し: 消化器の生検方法と病理検査
横山 望
第20回日本獣医内科学アカデミー学術大会, 25 Feb. 2024, Japanese, Public discourse
23 Feb. 2024 - 25 Feb. 2024, [Invited]

意外と難しい!? 胆嚢の超音波検査
横山 望
第20回日本獣医内科学アカデミー学術大会, 24 Feb. 2024, Japanese, Public discourse
23 Feb. 2024 - 25 Feb. 2024, [Invited]

2次診療動物病院に来院した犬の糞便真核生物叢解析
横山 望; 川口 剛; 中尾 亮; 森下 啓太郎; 細谷 謙次; 永田 矩之; 笹岡 一慶; 新坊 弦也; 佐々木 東; 中村 健介; 滝口 満喜
日本獣医学会学術集会講演要旨集, Sep. 2022, (公社)日本獣医学会, Japanese
Sep. 2022 - Sep. 2022

低コレステロール血症は犬の膵外分泌不全を予測できるのか？
横山 望; 大田 寛; 永田矩之; 笹岡一慶; 新坊弦也; 佐々木 東; 森下啓太郎; 中村健介; 滝口満喜
北海道獣医師会 令和4年度地区学会, 01 Sep. 2022, Japanese, Oral presentation
01 Sep. 2022 - 01 Sep. 2022

知っておくべき病気シリーズ:下痢 -糞便検査と院内感染症対策-
横山 望
WJVF ONLINE 第13回大会, Japanese, Public discourse
08 Jul. 2022 - 14 Aug. 2022, [Invited]

猫の膵炎を考える -ACVIM consensus statement から学ぶ-
横山 望
日本臨床獣医学フォーラム 第23回年次大会 2021, Japanese, Invited oral presentation
19 Sep. 2021 - 31 Oct. 2021, [Invited]

まずは正確な診断から! 犬の急性膵炎の診るべきポ イント
横山 望
WJVF ONLINE 第12回大会, Invited oral presentation
19 Jul. 2021 - 15 Aug. 2021, [Invited]

犬猫における消化器の超音波検査 ～消化管を中心に～
横山 望
日本獣医師会獣医学術学会年次大会オンラインセミナー, 13 Mar. 2021, Invited oral presentation
[Invited]

肝・胆・膵の超音波検査
横山 望
第16回 日本獣医内科学アカデミー学術大会, 22 Feb. 2020, Invited oral presentation
21 Feb. 2020 - 23 Feb. 2020, [Invited]

見逃さない！消化管の感染症
横山 望
第16回 日本獣医内科学アカデミー学術大会, 23 Feb. 2020, Invited oral presentation
21 Feb. 2020, [Invited]

怖くない！ 低血糖に対する鑑別診断と対処法
横山 望
第15回 日本獣医内科学アカデミー学術大会, 16 Feb. 2019, Japanese, Public discourse
[Invited], [Domestic Conference]

感染性消化器疾患の新常識
横山 望
第15回 日本獣医内科学アカデミー学術大会, 15 Feb. 2019, Japanese, Public discourse
[Invited], [Domestic Conference]

犬猫の腸内細菌の役目を考える―腸内環境を整えて,感染症に勝つ―4.IBD治療とプレバイオティクス
横山望
動物臨床医学会年次大会プロシーディング, 16 Nov. 2018, Japanese

発芽大麦の犬の急性下痢に対する臨床効果
横山望; 大野耕一; 渡邊遥; 内海貴夫; 島綾香; 石原玄基; 小久保健; 中川泰輔; 富安博隆; 後藤(越野)裕子; 辻本元
日本獣医学会学術集会講演要旨集, 21 Aug. 2018, Japanese

胃腫瘍の診断アプローチ
横山 望
第14回日本獣医内科学アカデミー学術大会, 17 Feb. 2018, Japanese, Invited oral presentation
[Domestic Conference]

Plasma Essential Trace Element Concentrations in Dogs with Chronic Enteropathy.
Nozomu Yokoyama; Hiroshi Ohta; Hazuki Mizukawa; Yumiko Kagawa; Shouta Nakayama; Noboru Sasaki; Keitaro Morishita; Kensuke Nakamura; Yoshinori Ikenaka; Mayumi Ishizuka; Mistuyoshi Takiguchi
American colleage of veterinary internal medicine Forum 2016, 12 Jun. 2016, English, Oral presentation
Colorado convention center, Denver, Colorado, United States., [International presentation]

ミニチュア・ダックスフンドの炎症性結直腸ポリープ症例の結直腸粘膜におけるToll‐like receptor2,4の局在解析
横山望; 大田寛; 賀川由美子; 山崎淳平; 市居修; KHOIRUN Nisa; 森田智也; 大菅辰幸; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
日本獣医学会学術集会講演要旨集, 30 Aug. 2015, Japanese

超低脂肪食で治療した犬慢性腸症18例の回顧的検討
横山望; 大田寛; 佐々木東; 森下啓太郎; 中村健介; 滝口満喜
北海道獣医師会雑誌, 10 Aug. 2015, Japanese

ミニチュア・ダックスフンドの炎症性結直腸ポリープ症例の結直腸粘膜におけるclaudinの蛋白質発現解析
横山望; 大田寛; 森田智也; 大菅辰幸; LIM Sue Yee; 森下啓太郎; 中村健介; 滝口満喜
日本獣医学会学術集会講演要旨集, 11 Aug. 2014, Japanese

犬胃癌10症例における超音波検査所見
横山望; 大田寛; 中村健介; 森下啓太郎; 山崎真大; 滝口満喜
獣医麻酔外科学雑誌, 10 Jun. 2014, Japanese

慢性特発性偽性腸閉塞症が疑われた犬の1例
横山望; 大田寛; 橋場香野; 森下啓太郎; 中村健介; 山崎真大; 落合謙爾; 寺本英司; 滝口満喜
動物臨床医学会年次大会プロシーディング, 15 Nov. 2013, Japanese

両側性子宮分節性無形成から片側性子宮角捻転に至った犬の1例
横山望; 中村健介; 木村享史; 大田寛; 山崎真大; 滝口満喜
北海道獣医師会雑誌, 10 Aug. 2012, Japanese

外用ステロイド軟膏剤が有効であった慢性創傷の猫の1例
横山望; 山根剛; 野中雄一; 大野晃治; 藤原あずさ; 杉田圭輔; 井上春奈; 佐川涼子; 高島一昭; 小笠原淳子; 水谷雄一郎; 才田祐人; 和田優子; 塚田悠貴; 宮嵜大樹; 丹野翔伍; 山根義久
動物臨床医学会年次大会プロシーディング, 18 Nov. 2011, Japanese

膀胱欠損と尿管転位を認めた子宮発生異常のウサギの1例
横山望; 山根剛; 野中雄一; 大野晃治; 藤原あずさ; 杉田圭輔; 井上春奈; 佐川涼子; 高島一昭; 小笠原淳子; 水谷雄一郎; 才田祐人; 和田優子; 塚田悠貴; 宮嵜大樹; 丹野翔伍; 山根義久
動物臨床医学会年次大会プロシーディング, 18 Nov. 2011, Japanese

フィプロニル投与による中毒を疑ったウサギの1例
横山望; 山根剛; 野中雄一; 大野晃治; 藤原あずさ; 杉田圭輔; 井上春奈; 佐川涼子; 高島一昭; 小笠原淳子; 水谷雄一郎; 松本郁実; 才田祐人; 和田優子; 塚田悠貴; 宮嵜大樹; 山根義久
動物臨床医学会年次大会プロシーディング, 19 Nov. 2010, Japanese

潜在精巣の去勢手術後に発生した縫合糸反応性肉芽腫の犬の1例
横山望; 高島一昭; 山根剛; 野中雄一; 山根香菜子; 大野晃治; 藤原あずさ; 杉田圭輔; 小笠原淳子; 水谷雄一郎; 松本郁美; 才田祐人; 和田優子; 山根義久
動物臨床医学会年次大会プロシーディング, 20 Nov. 2009, Japanese

プレドニゾロン投与によって長期コントロールが可能であった肉芽腫性肝炎の犬の1例
横山望; 高島一昭; 山根剛; 野中雄一; 山根香菜子; 大野晃治; 藤原あずさ; 杉田圭輔; 小笠原淳子; 水谷雄一郎; 松本郁美; 才田祐人; 和田優子; 山根義久
動物臨床医学会年次大会プロシーディング, 20 Nov. 2009, Japanese

伴侶動物獣医療実習, 2024年, 学士課程, 獣医学部

Human-Animal Bond and One Health 特別科目群, 2024年, 博士後期課程, 獣医学院

プレクリニカル実習, 2024年, 学士課程, 獣医学部

Human-Animal Bond and One Health 特別科目群, 2024年, 博士後期課程, 国際感染症学院

伴侶動物獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部

伴侶動物獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部

伴侶動物獣医療実習Ⅱ, 2024年, 学士課程, 獣医学部

伴侶動物獣医療実習Ⅱ, 2024年, 学士課程, 獣医学部

夜間・救急獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部

夜間・救急獣医療実習Ⅰ, 2024年, 学士課程, 獣医学部

総合獣医療実習, 2024年, 学士課程, 獣医学部

総合獣医療実習, 2024年, 学士課程, 獣医学部

アドバンスト演習, 2024年, 学士課程, 獣医学部

アドバンスト演習, 2024年, 学士課程, 獣医学部

アドバンスト演習, 2024年, 学士課程, 獣医学部

プレクリニカル実習, 2024年, 学士課程, 獣医学部

アドバンスト演習, 2024年, 学士課程, 獣医学部

猫の好酸球性硬化性線維増殖症における局所リンパ球駆動型好酸球浸潤メカニズムの解明
科学研究費助成事業
01 Apr. 2026 - 31 Mar. 2029
横山 望
日本学術振興会, 基盤研究(C), 北海道大学, 26K09101

犬の慢性腸炎からリンパ腫への移行：Cathepsin Wの役割解明と診断・治療応用
科学研究費助成事業
Apr. 2026 - Mar. 2029
大田 寛, 横山 望
日本学術振興会, 基盤研究(C), 酪農学園大学, 26K09131

副腎皮質機能亢進症関連肝障害による肝細胞癌発症機序の解明
科学研究費助成事業
01 Apr. 2023 - 31 Mar. 2026
滝口 満喜; 村上 正晃; 佐々木 東; 新坊 弦也; 横山 望
日本学術振興会, 基盤研究(B), 北海道大学, 23K27067

Study on the mechanism of the development of intestinal lymphoma from chronic enteritis: detection of causative genes
Grants-in-Aid for Scientific Research
01 Apr. 2023 - 31 Mar. 2026
大田 寛; 横山 望
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C), Rakuno Gakuen University, 23K05573

副腎皮質機能亢進症関連肝障害による肝細胞癌発症機序の解明
科学研究費助成事業
01 Apr. 2023 - 31 Mar. 2026
滝口 満喜; 村上 正晃; 佐々木 東; 新坊 弦也; 横山 望
日本学術振興会, 基盤研究(B), 北海道大学, 23H02374

A study on the innate immune response in the colorectal mucosa of dogs with inflammatory colorectal polyps: analysis of toll-like receptors expression and function
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
01 Apr. 2014 - 31 Mar. 2017
Ohta Hiroshi; Yokoyama Nozomu
In this study, we examined the expression and function of Toll-like receptors (TLRs) in the colorectal mucosa of miniature dachshunds (MDs) with inflammatory colorectal polyps (ICRPs). By using in situ hybridization method, we examined the expression and localization ofTLR2 and TLR4. As a result, TLR2 and TLR4 mRNA were localized to the colorectal epithelium and inflammatory cells in the inflamed colorectal mucosa of dogs with ICRPs. In addition, we examined the effects of different TLR (TLR2, TLR4, TLR5 and TLR9) ligands on pro-inflammatory cytokines (IL-1β, IL-6, IL-8 and TNF-α) gene expression in ex vivo-cultured colorectal samples from MDs with ICRPs. After 4-hour incubation, TNF-α mRNA expression in the TLR2- or TLR4-stimulated colorectal samples, and IL-1β mRNA expression in the TLR9-stimulated colorectal samples form MDs with ICRPs were higher than healthy dogs.
Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B), Hokkaido University, 26850191

犬の慢性腸症における血中微量元素プロファイルの解析
スカラーシッププログラム
Aug. 2014 - Oct. 2015
横山 望
クリニカルニュートリション研究会, Principal investigator, Competitive research funding

ネコの筋ジストロフィーの診断方法、及び検査方法
Patent right, 山崎淳平; 松本 悠貴; 横山 望, アニコム損害保険株式会社, 国立大学法人北海道大学
特願2023-011864, 30 Jan. 2023
特開2024-107768, 09 Aug. 2024
202403007971255711