Taemaitree Farsai(Research Institute for Electronic Science　Photonics and Optical Science)

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Taemaitree Farsai

Research Institute for Electronic Science　Photonics and Optical Science Assistant Professor

Researcher basic information

■ Degree

Ph.D., Tohoku University, Mar. 2021

■ URL
researchmap URL

https://researchmap.jp/farsai?lang=en

■ Various IDs
Researcher number

30962485

ORCID ID

https://orcid.org/0000-0003-0295-9226

J-Global ID

202201004279745112

■ Research Keywords and Fields
Research Keyword

Nanoparticles

Drug Delivery Systems

Research Field

Nanotechnology/Materials, Nanobioscience

Nanotechnology/Materials, Nanomaterials

■ Educational Organization

Master's degree program, Graduate School of Information Science and Technology

Doctoral (PhD) degree program, Graduate School of Information Science and Technology

Career

■ Career
Career

Mar. 2022 - Present
Research Institute for Electronic Science, Assistant Professor, Japan

Mar. 2021 - Mar. 2022
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, JSPS Postdoctoral Researcher, Japan

Educational Background

Oct. 2018 - Mar. 2021, Tohoku University, Graduate School of Engineering, Department of Biomolecular Engineering, Doctoral Course, Japan

Oct. 2016 - Sep. 2018, Tohoku University, Graduate School of Engineering, Department of Biomolecular Engineering, Master Course, Japan

Oct. 2012 - Sep. 2016, Tohoku University, Faculty of Science, Advanced Molecular Chemistry, Japan

Research activity information

■ Awards

Dec. 2021, Pacifichem 2021, Winner of the Student Research Competition
Farsai Taemaitree

Mar. 2021, Tohoku University, Dean of Engineering Faculty Award
Farsai Taemaitree

Mar. 2021, The 101st Chemical Society Japan, Best Presentation Award
Investigation of SN-38 Anticancer Nano-prodrugs Intracellular Dynamics
Farsai Taemaitree

Feb. 2021, Annual Samaggi Abstract Competition 2021, Best Abstract and Presentation Award in the Biological & Medical Science Category
Intracellular investigation of carrier-free nano-prodrugs toward highly efficient anticancer drug delivery systems
Farsai Taemaitree

Nov. 2019, The Society of Polymer Science, Tohoku Branch, Best Presentation Award for Young Researcher
Surface Engineering of Nano-prodrugs for Highly Effective Anticancer Drug Delivery
Farsai Taemaitree

Dec. 2018, Tohoku University, Institute of Multidisciplinary Research for Advanced Materials, The 13th IMRAM Research Encouragement Award, Hatano scholarship
Development of Nano-prodrugs for Highly Effective Anticancer Drug Delivery
Farsai Taemaitree

Dec. 2017, International Symposium on Nanomedicine 2017, The Best Poster Award
Serum Protein-Stabilized Nano-prodrugs for Anticancer Drug Delivery
Farsai Taemaitree

Apr. 2017, Tohoku University, Tohoku University President Fellowship
Farsai Taemaitree

Sep. 2016, The 28th Chemical Society of Japan, Tohoku branch, Best Poster Award
Fabrication of protein-conjugated nanoprodrugs and control of their dispersion stability
Farsai Taemaitree

■ Papers

Raman Spectroscopy and FRAP Analysis on Density Heterogeneity and Diffusion Behavior of Complex Coacervation by Arginine-Rich Dipeptides and Poly-A RNA
Ya Tian; Qiang Zhang; Jiangtao Li; Motosuke Tsutsumi; Tomoko Inose; Farsai Taemaitree; Kenji Hirai; Kohsuke Kanekura; Hiroshi Uji-i
ACS Omega, American Chemical Society (ACS), 25 Aug. 2025
Scientific journal

Cellular Responses to Photothermal Therapy: Heat-Induced ERK Signaling and Intercellular Communication in Solid Tumors
Farsai Taemaitree; Yuta Takano; Daisuke Yamaguchi; Kazushi Yamaguchi; Yudai Yamashita; Motosuke Tsutsumi; Chentao Wen; Kohei Otomo; Kenji Hirai; James Hutchison; Indra Van Zundert; Sandra Krzyzowska; Maria Bravo; Sayuki Hirano; Koutarou D Kimura; Kazuhiro Aoki; Susana Rocha; Tomomi Nemoto; Beatrice Fortuni; Hiroshi Uji-i
Cold Spring Harbor Laboratory, 03 Mar. 2025
Abstract

Nanoparticle-mediated photothermal therapy (PTT) shows promise as a standalone cancer treatment but faces clinical challenges due to inconsistent efficacy. Its translation is further hindered by a limited understanding of plasmon-induced heat effects, such as stress responses and intercellular signaling. Here, we investigate how plasmon-induced local heating affects cellular behavior and fate within tumor spheroids by focusing on the activity of the extracellular signal-regulated kinase (ERK). Spheroids were prepared from HeLa cells that express a FRET-based ERK sensor, and ERK activity changes under photothermal stimuli were tracked using a deep-learning program, 3DeeCellTracker. Gold nanostars were used as highly efficient photothermal transducers. Our results revealed significant alterations in ERK signaling patterns upon photothermal stimulation compared to spontaneous ERK activity in untreated spheroids, including changes in the activation frequency, timing, and duration. Notably, photothermal-induced ERK activity propagated across neighboring cells within the spheroid, suggesting intercellular communication. Furthermore, analysis of cell death and division further demonstrated that laser power modulates cellular fate during photothermal therapy. This study provides insights for predicting the therapeutic effects of PPT and guides the rational design of next-generation photothermal strategies. Additionally, our approach demonstrates the potential of FRET-based biosensors and deep-learning tools as powerful methods to study the effects of various therapeutic stimuli on solid tumors at the single-cell level.

Optical cavity enhancement of visible light-driven photochemical reaction in the crystalline state.
Ikuto Sasaki; Kiyonori Takahashi; Farsai Taemaitree; Takayoshi Nakamura; James A Hutchison; Hiroshi Uji-I; Kenji Hirai
Chemical communications (Cambridge, England), 61, 13, 2766, 2769, 06 Feb. 2025, [International Magazine]
English, Scientific journal, Photochemical reactions enable the synthesis of energetically unfavorable compounds but often require irradiation with ultraviolet light, which potentially induces side reactions. Here, cavity strong coupling enhances the efficiency of an all-solid state photocyclization in crystals of 2,4-dimethoxy-β-nitrostyrene under irradiation with visible light. The exposure to visible light facilitates photocyclization by the transition to a lower polaritonic state, which is energetically lower than the original transition state.

Nanoparticle accumulation and penetration in 3D tumor models: the effect of size, shape, and surface charge
Pierre Cybulski; Maria Bravo; Jim Jui-Kai Chen; Indra Van Zundert; Sandra Krzyzowska; Farsai Taemaitree; Hiroshi Uji-i; Johan Hofkens; Susana Rocha; Beatrice Fortuni
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 12, 24 Jan. 2025
English, Scientific journal

Carrier-free nano-prodrugs for minimally invasive cancer therapy
Keita Tanita; Yoshitaka Koseki; Sanjay Kumar; Farsai Taemaitree; Asuka Mizutani; Hirotaka Nakatsuji; Ryuju Suzuki; Anh Thi Ngoc Dao; Fumiyoshi Fujishima; Hiroshi Tada; Takanori Ishida; Ken Saijo; Chikashi Ishioka; Hitoshi Kasai
Nanoscale, Royal Society of Chemistry (RSC), 2024
Scientific journal, SNC4DC, a dimer of SN-38 derivatives, has been synthesized. SNC4DC nanoparticles called nano-prodrugs are internalized into the cell and dissociate, and the active SN-38 is released after reduction of the S–S bond in the presence of GSH occurs.

Selective Detection of Intracellular Drug Metabolism by Metal‐Organic Framework‐Coated Plasmonic Nanowire
Qiang Zhang; Taku Murasugi; Kotomi Watanabe; Han Wen; Ya Tian; Monica Ricci; Susana Rocha; Tomoko Inose; Hitoshi Kasai; Farsai Taemaitree; Hiroshi Uji‐i; Kenji Hirai; Beatrice Fortuni
Advanced Optical Materials, Wiley, 21 May 2023
Scientific journal

Label-Free Tracking of Nanoprodrug Cellular Uptake and Metabolism Using Raman and Autofluorescence Imaging
Masato Machida; Toshiki Sugimura; Shinji Kajimoto; Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai; Takakazu Nakabayashi
The Journal of Physical Chemistry B, 127, 17, 3851, 3860, American Chemical Society (ACS), 24 Apr. 2023
Scientific journal

Liquid-Phase Photo-induced Covalent Modification (PICM) of Single-Layer Graphene by Short-Chain Fatty Acids
Guilin Feng; Tomoko Inose; Nozomu Suzuki; Han Wen; Farsai Taemaitree; Mathias Wolf; Shuichi Toyouchi; Yasuhiko Fujita; Kenji Hirai; Hiroshi Uji-i
Nanoscale, 15, 10, 4932, 4939, Royal Society of Chemistry (RSC), 2023
Scientific journal, We report an efficient photo-induced covalent modification (PICM) of graphene by short-chain fatty acids (SCFAs) with an alkyl chain at the liquid-solid interface for spatially resolved chemical functionalization of graphene....

Polymeric functionalization of podophyllotoxin carrier-free drug nanoparticles for enhancing bioavailability and in vitro cellular imaging
Farsai Taemaitree; Masamichi Tamada; Yoshitaka Koseki; Tsunenobu Onodera; Hidetoshi Oikawa; Hitoshi Kasai
Molecular Crystals and Liquid Crystals, 1, 7, Informa {UK} Limited, 24 Mar. 2022, [Peer-reviewed]
English, Scientific journal

Fabrication of size-controlled SN-38 pure drug nanocrystals through an ultrasound-assisted reprecipitation method toward efficient drug delivery for cancer treatment
Yoshitaka Koseki; Yoshikazu Ikuta; Farsai Taemaitree; Nozomi Saito; Ryuju Suzuki; Anh Thi Ngoc Dao; Tsunenobu Onodera; Hidetoshi Oikawa; Hitoshi Kasai
Journal of Crystal Growth, 572, 126265, 126265, Elsevier {BV}, Oct. 2021, [Peer-reviewed]
Scientific journal

Serum Albumin-treated SN-38 Prodrug Nanoparticles toward Cancer Treatment
Farsai Taemaitree; Yoshitaka Koseki; Anh Thi Ngoc Dao; Hitoshi Kasai
Chemistry Letters, 50, 8, 1555, 1558, The Chemical Society of Japan, 05 Aug. 2021, [Peer-reviewed]
English, Scientific journal

研究者の最新動向ナノ・プロドラッグ新たな抗がん薬輸送システムの細胞内挙動
小関良卓; Taemaitree Farsai; Fortuni Beatrice; Rocha Susana; 雲林院宏; 猪瀬朋子; 笠井均
Precision Medicine, 4, 8, 753, 758, (株)北隆館, Aug. 2021
Japanese

ナノ・プロドラッグ:新たな抗がん薬輸送システムの細胞内挙動
小関良卓; Taemaitree Farsai; Fortuni Beatrice; Rocha Susana; 雲林院宏; 猪瀬朋子; 笠井均
細胞, 52, 13, 769, 773, (株)ニュー・サイエンス社, Nov. 2020
Japanese

Self-assemble tannic acid and iron complexes on pure nanodrugs surface prevents aggregation and enhances anticancer drug delivery efficiency
Farsai Taemaitree; Yoshitaka Koseki; Nozomi Saito; Ryuju Suzuki; Anh Thi Ngoc Dao; Hitoshi Kasai
Molecular Crystals and Liquid Crystals, 706, 1, 116, 121, Informa {UK} Limited, 23 Jul. 2020, [Peer-reviewed]
English, Scientific journal

FRET-based intracellular investigation of nanoprodrugs toward highly efficient anticancer drug delivery
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Johan Hofkens; Hiroshi Uji-i; Tomoko Inose; Hitoshi Kasai
Nanoscale, 12, 32, 16710, 16715, 2020, [Peer-reviewed]
English, Scientific journal

Influence of Hydrolysis Susceptibility and Hydrophobicity of SN-38 Nano-Prodrugs on Their Anticancer Activity
Farsai Taemaitree
Bulletin of the Chemical Society of Japan, 15 Aug. 2019, [Peer-reviewed]
English, Scientific journal

■ Other Activities and Achievements

FRET-based intracellular investigation of nanoprodrugs toward highly efficient anticancer drug delivery (vol 12, pg 16710, 2020)
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Johan Hofkens; Hiroshi Uji-i; Tomoko Inose; Hitoshi Kasai, NANOSCALE, 12, 42, 21951, 21951, Nov. 2020
English, Others

ナノ・プロドラッグ：新たな抗がん薬輸送システムの細胞内挙動
Yoshitaka Koseki; Farsai Taemaitree; Beatrice Fortuni; Susana Rocha; Hiroshi Ujii; Tomoko Inose; Hitoshi Kasai, 細胞, 52, 13, 47, 51, Oct. 2020

■ Lectures, oral presentations, etc.

Plasmonic Nanowire SERS Endoscopy for Unveiling Intracellular Drug Dynamics
Farsai Taemaitree; Qiang Zhang; Susana Rocha; Tomoko Inose; James Andell Hutchison; Hitoshi Kasai; Kenji Hirai; Beatrice Fortuni; Hiroshi Uji-i
The 8th International Conference on Nanotechnology – NanoThailand 2023, 30 Nov. 2023

Evaluation of tumor penetration and drug release dynamics of liposome-modified nano-prodrugs in 3D cancer spheroid
Farsai Taemaitree
The 7th Australia-Belgium-Japan joint symposium on excitonics and cellular communication, 24 Nov. 2023
[Invited]

Intracellular investigation of carrier-free nano-prodrugs dynamics toward highly efficient anticancer drug delivery systems
Farsai Taemaitree
The 45th Annual Meeting of Japanese Society for Biomaterials, 07 Nov. 2023

Fabrication of liposome-coated nano-prodrugs and investigation of drug release dynamics
Farsai Taemaitree; Musashi Kazui; Beatrice Fortuni; Yoshitaka Koseki; Anh Thi Ngoc Dao; Ryuju Suzuki; Hiroshi Uji-i; Hitoshi Kasai
The 9th Hokkaido University Cross-Departmental Symposium, 11 Oct. 2023

Visualization of ERK Activity Induced by Plasmonic Nanoparticles-Assisted Photothermal Stimulation
Farsai Taemaitree
The 6th Australia-Belgium-Japan joint online symposium on excitonics and cellular communication, 20 Mar. 2023
[Invited]

Visualization of Extracellular Signal-Regulated Kinase Activity Induced by Plasmonic Photothermal Effect
Farsai Taemaitree
The University of Melbourne-Hokkaido University Workshop on Therapeutics Nanoparticle, 22 Feb. 2023
[Invited]

Investigation of nano-prodrugs intracellular dynamics toward highly efficient anticancer drug delivery systems
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Johan Hofkens; Hiroshi Uji-i; Tomoko Inose; Hitoshi Kasai
The 23rd RIES-HOKUDAI International Symposium, 05 Dec. 2022, Poster presentation

Investigation of carrier-free nano-prodrugs intracellular dynamics
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Johan Hofkens; Hiroshi Uji-i; Tomoko Inose; Hitoshi Kasai
MAF2022, 13 Sep. 2022, Poster presentation

リポソームにより表面修飾したSN-38ナノ・プロドラッグの作製および抗がん活性評価に関する研究
Musashi Kazui; Farsai Teamaitree; Yoshitaka Koseki; Anh T; N. Dao; Ryuju Suzuki; Hitoshi Kasai
The 102th CSJ Annual Meeting, 26 Mar. 2022, Oral presentation

有機ナノ粒子の細胞内溶解過程を追跡できる高発光性ナノ粒子の開発
Yutaro Miki; Farsai Taemaitree; Ryuju Suzuki; Yoshitaka Koseki; Anh T; N. Dao; Ruito Hashimoto; Atsushi Wakamiya; Hitoshi Kasai
The 102nd CSJ Annual Meeting, 26 Mar. 2022, Oral presentation

Multi-Functionalize Silk Protein-Based Drug-Carriers via Coalescence with Noble Metallic Nanostructures
Anh T. N. Dao; Motofumi Nakamura; Farsai Taemaitree; Hitoshi Kasai
2021 International Chemical Congress of Pacific Basin Societies, 17 Dec. 2021, Invited oral presentation
[Invited]

Intracellular investigation of SN-38 prodrug nanoparticles as carrier-free anticancer drug delivery systems
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Hiroshi Uji-i; Tomoko Inose; Hitoshi Kasai
2021 International Chemical Congress of Pacific Basin Societies, 17 Dec. 2021, Oral presentation

Fabrication of Fluorescent Nanoprobes Based on FRET And Analysis of Intracellular Behavior of Organic Nanoparticles
Yutaro Miki; Farsai Taemaitree; Ryuju Suzuki; Yoshitaka Koseki; Anh T.N. Dao; Ruito Hashimoto; Atsushi Wakamiya; Hitoshi Kasai
第21回東北大学多元物質科学研究所研究発表会, 09 Dec. 2021, Poster presentation

Facile Fabrication of Silk Protein for a Versatile Drug Carrier
Anh T. N. Dao; Farsai Taemaitree; Motofumi Nakamura; Ryuju Suzuki; Yoshitaka Koseki; Hitoshi Kasai
MRS Fall 2021 Meeting, 06 Dec. 2021, Oral presentation

Fabrication of injectable silk hydrogel for controlling the release of various anticancer drugs
Mengheng Yang; Anh T.N. Dao; Farsai Taemaitree; Ryuju Suzuki; Yoshitaka Koseki; Hitoshi Kasai
VANJ Conference 2021, 05 Dec. 2021, Poster presentation

Dual pH- and Thermo-Responsive Au/Silk Nanocarrier for Cancer Therapy
Anh T. N. Dao; Ryota Sawamura; Ryunosuke Karashimada; Nobuhiko Iki; Farsai Taemaitree; Hitoshi Kasai
The 8th Ensemble Workshop for Young researchers in Tohoku University, 17 Nov. 2021, Poster presentation

Fabrication of highly fluorescent FRET NPs for the investigation of intracellular behavior
Yutaro Miki; Farsai Taemaitree; Ryuju Suzuki; Yoshitaka Koseki; Anh T.N. Dao; Ruito Hashimoto; Atsushi Wakamiya; Hitoshi Kasai
The 14th International Symposium on Nanomedicine, 17 Nov. 2021, Poster presentation

FRET-Based Investigation of Carrier-Free Drug Nanoparticles Fate Inside Cancer Cells
Farsai Taemaitree; Hitoshi Kasai
The 14th International Symposium on Nanomedicine, 17 Nov. 2021, Invited oral presentation
[Invited]

Design and fabrication of anticancer nano-prodrugs for the investigation of their intracellular dynamics
Farsai Taemaitree; Hitoshi Kasai
The 4th Australia-Belgium-Japan joint open symposium on excitonics and cellular communication, 22 Oct. 2021, Invited oral presentation
[Invited]

Fabrication of injectable silk hydrogel for controlling the release of various anticancer drugs
Yang Mengheng; Anh T. N. Dao; Farsai Taemaitree; Ryuju Suzuki; Yoshitaka Koseki; Hitoshi Kasai
Joint Meeting of the Tohoku Area Chemistry Societies 2021, 03 Oct. 2021, Poster presentation

Polymeric Functionalization of Podophyllotoxin Carrier-free Drug Nanoparticles for Enhancing Bioavailability and In Vitro Cellular Imaging
Farsai Taemaitree; Masamichi Tamada; Yoshitaka Koseki; Tsunenobu Onodera; Hidetoshi Oikawa; Hitoshi Kasai
KJF-ICOMEP2021, 30 Aug. 2021, Oral presentation

Facile Fabrication and Surface Modification of Silk Protein for a Versatile Drug Carrier
Anh T. N. Dao; Farsai Taemaitree; Motofumi Nakamura; Ryuju Suzuki; Yoshitaka Koseki; Hitoshi Kasai
ACS Fall 2021 Meeting, 22 Aug. 2021, Oral presentation

フィルムに担持した薬剤ナノ粒⼦の抗腫瘍活性評価
Nozomi Saito; Farsai Taemaitree; Ryuju Suzuki; Yoshitaka Koseki; Hitoshi Kasai
The 101st CSJ Annual Meeting, 22 Mar. 2021, Oral presentation

Investigation of SN-38 Anticancer Nano-prodrugs Intracellular Dynamics
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Johan Hofkens; Hiroshi Uji-i; Anh Thi Ngoc Dao; Ryuju Suzuki; Tomoko Inose; Hitoshi Kasai
The 101st CSJ Annual Meeting, 22 Mar. 2021, Oral presentation

Development of Fabrication Technique for Drug Nanoparticles toward Efficient Cancer Therapy
Yoshitaka Koseki; Yoshikazu Ikuta; Farsai Taemaitree; Nozomi Saito; Ryuju Suzuki. Anh Thi; Ngoc Dao; Tsunenobu Onodera; Hidetoshi Oikawa; Hitoshi Kasai
The 8th Asian Conference on Crystal Growth and Crystal Technology, 03 Mar. 2021, Oral presentation

Intracellular investigation of carrier-free nano-prodrugs toward highly efficient anticancer drug delivery systems
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Johan Hofkens; Hiroshi Uji-i; Ryuju Suzuki; Anh Dao; Tomoko Inose; Hitoshi Kasai
Samaggi Abstract Competition 2021, 21 Jan. 2021, Oral presentation

Intracellular investigation of SN-38 nano-prodrugs toward anticancer drug delivery applications
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Hiroshi Uji-I; Johan Hofkens; Anh T. N. Dao; Ryuju Suzuki; Tomoko Inose; Hitoshi Kasai
東北大学＆理化学研究所連携シンポジウム, 01 Dec. 2020, Poster presentation

Silk Protein Modified by Noble Metal for a Multifunctional Drug Delivery System
Anh T. N. Dao; Motofumi Nakamura; Farsai Taemaitree; Hitoshi Kasai
2020 Tohoku University & Taipei Tech. Joint Symposium, 30 Nov. 2020, Invited oral presentation
[Invited]

Fabrication of Silk Protein to Hybrid Nanocarriers for Cancer Therapy
Anh T. N. Dao; Motofumi Nakamura; Farsai Taemaitree; Hitoshi Kasai
VANJ Conference 2020, 28 Nov. 2020, Invited oral presentation
[Invited]

Intracellular investigation of nanoprodrugs towards anticancer drug delivery application
Farsai Taemaitree; Beatrice Fortuni; Yoshitaka Koseki; Eduard Fron; Susana Rocha; Johan Hofkens; Hiroshi Uji-i; Tomoko Inose; Hitoshi Kasai
PHyM 2020 Young Researcher Forum, 19 Oct. 2020, Oral presentation

Polymeric engineering of prodrug nanoparticles for the investigation of intracellular drug dynamics
Farsai Taemaitree; Beatrice Fortuni; Tomoko Inose; Yoshitaka Koseki; Hiroshi Uji-I; Hitoshi Kasai
The 69th SPSJ Annual Meeting, 29 May 2020, Poster presentation

フィルムに担持した抗がん剤ナノ粒子の再放出挙動と薬効評価
Nozomi Saito; Farsai Taemaitree; Ryuju Suzuki; Yoshitaka Koseki; Hitoshi Kasai
The 69th SPSJ Annual Meeting, 29 May 2020, Poster presentation

Fabrication SN-38 Nano-Prodrugs and Their Anticancer Activity
Yoshitaka Koseki; Yoshikazu Ikuta; Liman Cong; Mayumi Takano-Kasuya; Hiroshi Tada; Mika Watanabe; Kohsuke Gonda; Takanori Ishida; Noriaki Ohuchi; Keita Tanita; Farsai Taemaitree; Anh T. N. Dao; Tsunenobu Onodera; Hidetoshi Oikawa; Hitoshi Kasai
The 100th CSJ Annual Meeting, 23 Mar. 2020, Oral presentation

高分子フィルムへの薬剤ナノ粒子の担持と放出挙動
Nozomi Saito; Farsai Taemaitree; Ryuju Suzuki; Yohitaka Koseki; Hitoshi Kasai
The 100th CSJ Annual Meeting, 23 Mar. 2020, Oral presentation

ドラッグデリバリーシステムのためのシルクナノ粒子の作製と特性評価
Motofumi Nakamura; Farsai Taemaitree; Anh T. N. Dao; Hitoshi Kasai
The 100th CSJ Annual Meeting, 23 Mar. 2020, Oral presentation

Fabrication of Silk Protein with Metallic Nanoparticles for a Multifunctional Drug Delivery System
Anh T.N. Dao; Motofumi Nakamura; Farsai Taemaitree; Hitoshi Kasai
2nd G'L'owing Polymer Symposium in KANTO, 30 Nov. 2019, Oral presentation

Surface Functionalization of Prodrug Nanoparticles Toward Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Ryuju Suzuki; Anh T. N. Dao; Hitoshi Kasai
2nd G'L'owing Polymer Symposium in KANTO, 30 Nov. 2019, Oral presentation

Surface Engineering of Nano-prodrugs for Highly Effective Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Ryuju Suzuki; Anh Thi Ngoc Dao; Hitoshi Kasai
The Society of Polymer Science, Tohoku Meeting 2019, 14 Nov. 2019, Oral presentation

Design and Fabrication of Noble Metallic Nanoparticles for Bioapplications
Anh T.N. Dao; Motofumi Nakamura; Farsai Taemaitree; Hitoshi Kasai
Tohoku-Melbourne Joint Workshop - Materials Science, 09 Nov. 2019, Oral presentation

Fabrication of Au/Silk Nanocarriers and the in vitro Evaluation for Cancer Therapy
Anh T.N. Dao; Motofumi Nakamura; Farsai Taemaitree; Hitoshi Kasai
Okinawa Colloids 2019, 08 Nov. 2019, Invited oral presentation
[Invited]

Surface Modification of SN-38 Nano-Prodrugs for Enhancing the Efficiency of Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Ryuju Suzuki; Anh T. N. Dao; Hitoshi Kasai
Okinawa Colloids 2019, 06 Nov. 2019, Poster presentation

Tannic acid-modified SN-38 nano-prodrugs toward effective anticancer drug delivery
Nozomi Saito; Farsai Taemaitree; Yoshitaka Koseki; Ryuju Suzuki; Anh Thi Ngoc Dao; Hitoshi Kasai
Sendai-Albi Knowledge in Engineering Seminars, 24 Oct. 2019, Poster presentation

Fabrication of Au/Silk hybrid nanoparticles for drug delivery applications
Motofumi Nakamura; Farsai Taemaitree; Anh T. N. Dao; Hitoshi Kasai
Joint Meeting of the Tohoku Area Chemistry Societies 2019, 22 Sep. 2019, Poster presentation

Gold coated silver nanoflowers toward SERS-based intracellular pH sensing with low cytotoxicity
Qiang Zhang; Kiri Watanabe; Ibuki Kotani; Beatrice Fortuni; Farsai Taemaitree; Hitoshi Kasai; Johan Hofkens; Kenji Hirai; Tomoko Inose; Hiroshi Uji-I
The 80th JSAP Autumn Meeting 2019, 20 Sep. 2019, Oral presentation

Effect of serum protein on dispersion stability and anticancer activity of SN-38 nano-prodrugs
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
The 33rd Conference of the European Colloid and Interface Society, 10 Sep. 2019, Poster presentation

Self-Assemble Tannic Acid and Iron Complexes on Nano-Prodrugs Surface Prevents Aggregation and Enhances Anticancer Drug Delivery Efficiency
Farsai Taemaitree; Yoshitaka Koseki; Nozomi Saito; Ryuju Suzuki; Anh Thi Ngoc Dao; Hitoshi Kasai
KJF-ICOMEP2019, 28 Aug. 2019, Poster presentation

Fabrication of liposome-coated SN-38 nano-prodrugs
Keitaro Yamauchi; Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
The 12th Tohoku University's Chemistry Summer School 2019, 28 Aug. 2019, Invited oral presentation
[Invited]

Fabrication of Au/Silk hybrid nanocarriers for drug delivery system
Motofumi Nakamura; Farsai Taemaitree; Anh T. N. Dao; Hitoshi Kasai
The 12th Tohoku University's Chemistry Summer School 2019, 27 Aug. 2019, Poster presentation

Modification of Nano-Prodrugs by Serum Proteins
Yoshitaka Koseki; Farsai Taemaitree; Hitoshi Kasai
1st G’L’owing Polymer Symposium in KANTO, 15 Dec. 2018, Oral presentation

Self-Assembly of Tannic Acid and Iron Complexes on SN-38 Derivatives Nano-Prodrugs for Effective Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
International Conference on Nanomedicine and Nanobiotechnology 2018, 27 Sep. 2018, Poster presentation

Surface Modification of SN-38 Nano-Prodrugs for Enhancing the Efficiency of Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
第八回ナノカーボンバイオシンポジウム, 10 Sep. 2018, Oral presentation

Tannic Acid and Iron Complexes Coated SN-38 Derivatives Nano-prodrugs for Effective Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
Collaborative Conference on Materials Research 2018, 25 Jun. 2018, Poster presentation

Metal Phenolic Network Coated Nano-prodrugs for Effective Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Yi Ju; Keita Tanita; Danzi Song; Frank Caruso; Hitoshi Kasai
International workshop on Mineral processing and Metallurgy 2018, 02 Mar. 2018, Poster presentation

Serum Protein-Stabilized Nano-prodrugs for Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
International Symposium on Nanomedicine 2017, 11 Dec. 2017, Poster presentation

Bovine serum albumin enhances dispersion stability and influence the anticancer activity of SN-38-5β-cholanate nanoprodrug
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
PHyM 2017 Young Researcher Forum, 11 Dec. 2017, Poster presentation

Serum Protein-Stabilized Nano-prodrugs of 5β-cholanic acid-conjugated SN-38 for Anticancer Drug Delivery
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
The Symposium on Advanced Materials, Scientific & Engineering Challenges, Part4, Tohoku University, 08 Nov. 2017, Poster presentation

Fabrication of Nano-prodrugs and effect of serum protein on their dispersion stability and anti-cancer activity
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
第26回有機結晶シンポジウム, 04 Nov. 2017, Oral presentation

Surface modification of nano-prodrugs and evaluation of their anti-cancer activities
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
The 45th Summer Joint Seminar for Polymer Science Young Researcher in Tohoku Region, 07 Jul. 2017, Poster presentation

Fabrication of nano-prodrugs and their interaction with serum proteins
Farsai Taemaitree; Yoshitaka Koseki; Tsunenobu Onodera; Hidetoshi Oikawa; Hiroshi Kadokura; Hitoshi Kasai
The 3nd Ensemble Workshop for Young researchers in Tohoku University, 03 Jul. 2017, Poster presentation

ナノ・プロドラッグの分散安定性の向上を目指した表面修飾法の開発
Risa Ito; Yoshitaka Koseki; Farsai Taemaitree; Hitoshi Kasai
The 97th CSJ Annual Meeting, 16 Mar. 2017, Oral presentation

Bovine Serum Albumin Conjugated Nano-prodrugs and Their Anti-cancer Efficacy
Farsai Taemaitree; Yoshitaka Koseki; Hitoshi Kasai
The 97th CSJ Annual Meeting, 16 Mar. 2017, Oral presentation

分散安定性の向上を目指したナノ・プロドラッグの表面修飾法の開発
Risa Ito; Yoshitaka Koseki; Farsai Taemaitree; Hitoshi Kasai
PHyM 2016 Young Researcher Forum, 27 Feb. 2017, Poster presentation

Fabrication of protein-conjugated nano-prodrugs and evaluation of their anti-cancer activities
Farsai Taemaitree; Yoshitaka Koseki; Tsunenobu Onodera; Hidetoshi Oikawa; Hiroshi Kadokura; Hitoshi Kasai
The 6th CSJ Chemistry Festa, 15 Nov. 2016, Poster presentation

Fabrication of protein-conjugated nano-prodrugs and control of their dispersion stability
Farsai Taemaitree; Yoshitaka Koseki; Tsunenobu Onodera; Hidetoshi Oikawa; Hiroshi Kadokura; Hitoshi Kasai
Joint Meeting of the Tohoku Area Chemistry Societies 2016, 10 Sep. 2016, Poster presentation

Fabrication of nano-prodrugs and control of their dispersion stability through nanoparticle-protein interaction
Farsai Taemaitree; Yoshitaka Koseki; Tsunenobu Onodera; Hidetoshi Oikawa; Hiroshi Kadokura; Hitoshi Kasai
The 9th Tohoku University's Chemistry Summer School 2016, 10 Sep. 2016, Invited oral presentation
[Invited]

Fabrication of nano-prodrugs and their interaction with serum proteins
Farsai Taemaitree; Yoshitaka Koseki; Tsunenobu Onodera; Hidetoshi Oikawa; Hiroshi Kadokura; Hitoshi Kasai
The 2nd Ensemble Workshop for Young researchers in Tohoku University, 12 Jul. 2016, Poster presentation

■ Syllabus

ナノマテリアル特論, 2024年, 修士課程, 情報科学院

ナノマテリアル特論, 2024年, 博士後期課程, 情報科学研究科

ナノマテリアル特論, 2024年, 博士後期課程, 情報科学院

生体情報工学実験Ⅰ, 2024年, 学士課程, 工学部

生体情報工学実験Ⅱ, 2024年, 学士課程, 工学部

■ Affiliated academic society

Jan. 2020 - Present
The Society of Polymer Science, Japan

Jan. 2016 - Present
The Chemical Society of Japan

■ Research Themes