Researcher basic information

• 博士（獣医学）, 北海道大学

• https://researchmap.jp/minamiWO?lang=en

• reproduction physiology
• wildlife
• 人工繁殖
• 精漿
• 子宮
• 生殖免疫
• アライグマ
• 豚
• イルカ

• Life Science, Veterinary medical science
• Life Science, Animal life science
• Life Science, Animal production science

Research activity information

• Sep. 2025, 日本獣医学会, 第168回 日本獣医学会学術集会 繁殖分科会長賞
  「牛子宮内膜外側を構成する筋層区分に関する解釈の検討」
  阿部茜;佐野光璃;奥山みなみ;中田健;杉浦智親
• Nov. 2017, 日本実験動物技術者協会, 第37回 日本実験動物技術者協会九州支部発表会 発表賞
  「ヤギの飼養管理の実際について」
  牧宏信;野田剛二;秋吉知;濱松典子;中島由美子;奧山みなみ
• Dec. 2014, 日本ウマ科学会, 第27回 日本ウマ科学会学術集会 優秀発表賞
  「馬胎子性腺および胎盤、子宮におけるインヒビ ン・アクチビン鎖およびアクチビン受容体の mRNA発現量」
  福田一平;前田洋佑;村瀬晴崇;佐藤文夫;片桐成二;奥山みなみ;南保泰雄
• Sep. 2014, 日本獣医学会, 第157回 日本獣医学会学術集会 繁殖学分科会長賞
  「経産豚の子宮内膜における人工授精後のサイトカイン発現変化と受胎性の関係」
  奥山みなみ;社浦宗徳;柳川洋二郎;森好政晴;片桐成二
• Mar. 2014, 北海道大学, 2014年度 北海道大学大塚賞
  奥山みなみ

• A local case report of dispersal characteristics in two male raccoons (Procyon lotor) in Oita Prefecture, Japan, revealed using Geographic Information System
  Minami W Okuyama; Yoshihisa Tsurunari; Ken-ichiro Shimada; Kei Uchida
  Jpn. J. Vet. Res., 74, 1, 35, 41, Mar. 2026, [Peer-reviewed], [Lead author, Corresponding author]
  English, Scientific journal
• Wildlife Exposure Rates to Oz Virus vs. Severe Fever with Thrombocytopenia Syndrome Virus in Oita Prefecture, Japan
  Takehiro Hashimoto; Takaaki Yahiro; Minami W Okuyama; Khan Sakirul; Kazunori Kimitsuki; Kazufumi Hiramatsu; Akira Nishizono
  American Journal of Tropical Medicine & Hygiene, 114, 1, 194, 196, 13 Nov. 2025, [Peer-reviewed], [International Magazine]
  English, Scientific journal
• Veterinary treatments and management care for urolithiasis and bloat of goats kept as experimental animals.
  Yumiko NAKASHIMA; Takayuki KAWASHIMA; Keitaro OKAMOTO; Tadashi UMENO; Kazuki MORI; Shinji MIYAMOT; Minami W. OKUYAMA
  Kyushu Journal of Experiment Animals, 41, 51, 58, Oct. 2025, [Peer-reviewed], [Last author, Corresponding author], [Domestic magazines]
  Japanese, Scientific journal
• Artificial insemination of the bottlenose dolphin (Tursiops truncatus); a trial with simple instruments and on criteria for estrous behavior linked to changes in the estradiol level and follicle development
  Sawa S.; Kawahiro N.; Okuyama MW
  Journal of Reproduction and Development, 71, 1, 62, 67, Feb. 2025, [Peer-reviewed], [Last author], [International Magazine]
  English, Scientific journal
• Changes in interleukin-2, -4, -6 and -8 expression in the postovulatory sow endometrium after artificial insemination based on conceived or failed to conceive
  Okuyama MW; Moriyoshi M; Katagiri S
  Journal of Reproduction and Development, 70, 3, 192, 196, Japanese Society of Animal Reproduction, Apr. 2024, [Peer-reviewed], [Lead author, Corresponding author]
  Scientific journal
• A Case Report of Acute Cardiac Tamponade Creation in a Macaque: Echo-Guided Catheter Manipulation to Perforate Coronary Artery.
  Takanari H; Okuyama MW; Kuroki K; Kondo H; Kira S; Miura M; Takahashi N; Okuda T
  Yonago Acta Medica, 66, 1, 192, 195, Feb. 2023, [Peer-reviewed], [Domestic magazines]
  English, Scientific journal, Although acute cardiac tamponade is one of the major problems in clinical practice, a suitable animal model is still lacking. We tried to create acute cardiac tamponade in macaques by echo-guided catheter manipulation. A 13-year-old male macaque was anesthetized, and a long sheath was inserted into the left ventricle via the left carotid artery under the guidance of transthoracic echocardiography. The sheath was then inserted into the orifice of the left coronary artery to perforate the proximal site of the left anterior descending branch. A cardiac tamponade was successfully created. Injection of diluted contrast agent into the pericardial space via a catheter made it possible to clearly distinguish between the hemopericardium and the surrounding tissues on postmortem computed tomography. This procedure did not need an X-ray imaging system during catheterization. Our present model would help us examine the intrathoracic organs in the presence of acute cardiac tamponade.
• Distribution of Severe Fever with Thrombocytopenia Syndrome Virus and Antiviral Antibodies in Wild and Domestic Animals in Oita Prefecture, Japan.
  Hashimoto T; Yahiro T; Yamada K; Kimitsuki K; Okuyama MW; Honda A; Kato M; Narimatsu H; Hiramatsu K; Nishizono A
  The American journal of tropical medicine and hygiene, 106, 5, 1547, 1551, 28 Feb. 2022, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Severe fever with thrombocytopenia syndrome (SFTS) is an emerging life-threatening infectious disease caused by the tickborne SFTS virus (SFTSV), first identified in China in 2009 and then in Japan in 2013. Human SFTS cases were reported to be concentrated in western Japan, but the epidemiological conditions of SFTSV infection in a specific region are still obscure. We performed an epidemiological study of SFTSV in Oita Prefecture on the island of Kyushu, located in western Japan. For our research, we collected sera from wild and domestic animals (deer, wild boars, raccoons, cats, and dogs) and ticks from January 2010 to November 2020 in Oita. The anti-SFTSV antibody positivity rate of deer in 2014 was significantly higher than that in 2011 (65% versus 27%, P < 0.001). The anti-SFTSV antibody positivity rates of deer, wild boars, raccoons, wild dogs, domestic dogs, and domestic cats were 55%, 12%, 27%, 1.8%, 0.53%, and 1.4%, respectively. Moreover, RT-PCR could not detect SFTSV in any tick sample. Of the six areas of Oita Prefecture, only the Eastern area showed no incidence or possibility of SFTSV infection among wild and domestic animals, ticks, and human beings. Further investigation is required to assess whether local seroepidemiology in animals will help assess the risk of SFTSV infections in inhabitants.
• Serotonin-manipulated juvenile green sea turtles Chelonia mydas exhibit reduced fear-like behaviour
  Kudo H; Okuyama MW; Sakamoto KQ; Uchida K; Sato K
  Endangered Species Research, 46, 185, 191, Nov. 2021, [Peer-reviewed]
  English, Scientific journal
• 経胸壁心エコーガイド下カテーテル法による急性心タンポナーデ動物実験モデルの開発
  奥田 貴久; 高成 広起; 奥山 みなみ; 黒木 浩二; 三浦 真弘
  日本法医学雑誌, 74, 1, 83, 83, (NPO)日本法医学会, Aug. 2020
  Japanese
• Genetic population structure of invasive raccoons (Procyon lotor) in Hokkaido, Japan: Unique phenomenon caused by pet escape or abandonment.
  Okuyama MW; Shimozuru M; Nakai M; Yamaguchi E; Fujii K; Shimada K; Ikeda T; Tsubota T
  Scientific reports, 10, 1, 8108, 8108, 15 May 2020, [Peer-reviewed], [Lead author, Corresponding author], [International Magazine]
  English, Phylogeographic studies can resolve relationships between genetic population structure of organisms and geographical distributions. Raccoons have become feral in Japan, and in Hokkaido island, they have been rapidly increasing in number and spreading since the 1970s. We analyzed mitochondrial (mtDNA) and microsatellite DNA to understand the current phylogenetic distribution and invasive founder events. Overall, Hokkaido raccoons maintained high genetic diversity (i.e., the level of heterozygosity was comparable to the original habitat, North America). Based on mtDNA distribution and microsatellite diversity, Hokkaido raccoons were divided into six management units. However, mtDNA haplotype distributions and genetic structures based on microsatellites did not always correspond to each other (e.g., two geographically and genetically separated populations showed similar mtDNA distributions). In addition, a high degree of genetic admixture was observed in every unit, and the degree of genetic differentiation was low even between regions separated by long distances. Compared with other countries in Europe where genetic distribution of introduced raccoons is more clearly structured, the current results represent a unique and complex phenomenon of pet escape/abandonment in Hokkaido: i.e., genetically related colonies were introduced into multiple regions as founder events, resulting in the current state in which raccoons are not clearly genetically differentiated even 40 years after introduction.
• 豚の受精卵移植技術の現状と繁殖指標の評価方法の確立
  奥山 みなみ
  九州実験動物雑誌, 34, 9, 13, Nov. 2018, [Invited], [Lead author, Corresponding author]
  特別寄稿
• ヤギの飼養管理の実際について
  牧宏信; 野田剛二; 秋吉知; 濱松典子; 中島由美子; 奥山みなみ
  日本実験動物技術者協会 九州支部会報, 41, 23, 34, Aug. 2018, [Invited], [Last author, Corresponding author]
• Steroidogenic enzymes, their products and sex steroid receptors during testis development and spermatogenesis in the domestic cat (Felis catus)
  Braun BC; Okuyama MW; Müller K; Dehnhard M; Jewgenow K
  Journal of Steroid Biochemistry and Molecular Biology, 178, 135, 149, Elsevier Ltd, 01 Apr. 2018, [Peer-reviewed]
  English, Scientific journal
• A transvaginal endoscopy-based technique for performing ovarian examinations in sows
  Okuyama MW,; Sugiura T; Moriyoshi M; Yamashita K; Tamura J; Katagiri S
  JOURNAL OF REPRODUCTION AND DEVELOPMENT, 63, 6, 617, 622, Dec. 2017, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Comparative analysis of intraluteal steroidogenic enzymes emphasises the functionality of fresh and persistent corpora lutea during pro-and metoestrus in the lynx
  Zschockelt L; Amelkina O; Koster S; Painer J; Okuyama MW; Serra R; Vargas A; Jewgenow K; Braun BC
  JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 154, 75, 84, Nov. 2015, [Peer-reviewed]
  English, Scientific journal
• A Genetic Method for Sex Identification of Raccoons (Procyon lotor) with Using the ZFX and ZFY Genes
  Okuyama MW; Shimozuru M; Tsubota T
  JOURNAL OF VETERINARY MEDICAL SCIENCE, 76, 5, 773, 775, May 2014, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Changes in the Immunolocalization of Steroidogenic Enzymes and the Androgen Receptor in Raccoon (Procyon lotor) Testes in Association with the Seasons and Spermatogenesis
  Okuyama MW; Shimozuru M; Yanagawa Y; Tsubota T
  JOURNAL OF REPRODUCTION AND DEVELOPMENT, 60, 2, 155, 161, Apr. 2014, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Timing of Puberty and Its Relationship with Body Growth and Season in Male Raccoons (Procyon lotor) in Hokkaido
  Okuyama MW; Shimozuru M; Abe G; Nakai M; Sashika M; Shimada K; Takahashi N; Fukui D; Nakamura R; Tsubota T
  JOURNAL OF REPRODUCTION AND DEVELOPMENT, 59, 4, 361, 367, Aug. 2013, [Peer-reviewed], [Lead author]
  English, Scientific journal
• Seasonal Changes in Spermatogenesis and Peripheral Testosterone Concentration in Raccoons (Procyon lotor) in Hokkaido
  Okuyama MW; Shimozuru M; Takahashi N; Fukui D; Nakamura R; Tsubota T
  JOURNAL OF VETERINARY MEDICAL SCIENCE, 74, 6, 727, 732, Jun. 2012, [Peer-reviewed], [Lead author]
  English, Scientific journal