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Search DetailsRyuzaki Sou
| Faculty of Science Chemistry Inorganic and Analytical Chemistry | Associate Professor |
Researcher basic information
■ Degree■ URL
researchmap URLホームページURL■ Various IDs
J-Global ID■ Research Keywords and Fields
Research KeywordResearch Field
- Nanotechnology/Materials, Analytical chemistry
- Life Science, Biophysics
- Nanotechnology/Materials, Nanobioscience
- Bachelor's degree program, School of Science
- Master's degree program, Graduate School of Chemical Sciences and Engineering
- Doctoral (PhD) degree program, Graduate School of Chemical Sciences and Engineering
Career
■ CareerCareer
- Apr. 2022 - Present
Hokkaido University, Faculty of Science Department of Chemistry, Associate Prof. - Jan. 2014 - Mar. 2022
Kyushu University, Institute for Materials Chemistry and Engineering, Assistant Professor - Oct. 2017 - Mar. 2021
Japan Science and Technology Agency, さきがけ研究員 - Feb. 2012 - Dec. 2013
Osaka University, The Institute of Scientific and Industrial Research, Assistant Professor - May 2011 - Feb. 2012
Tokyo Institute of Technology, 原子炉工学研究所, Postdoc - May 2010 - Apr. 2011
University of Copenhagen, Nano-Science Center, Postdoc
- Apr. 2007 - Mar. 2010, Tokyo Institute of Technology, Graduate School of Science and Engineering, Department of Nuclear Engineering, Japan
- Apr. 2005 - Mar. 2007, Tokyo Institute of Technology, Graduate School of Science and Engineering, Department of Nuclear Engineering, Japan
- Apr. 2001 - Mar. 2005, Tokyo University of Science, Faculty of Science and Technology, Physics, Japan
- Oct. 2022 - Present
DV−Xα研究協会, 会長補佐 - Apr. 2014 - Present
DV−Xα研究協会, 常任幹事, Society - Apr. 2024 - Mar. 2026
応用物理学会:有機分子・バイオエレクトロニクス分科会, 常任幹事, Society - Apr. 2024 - Mar. 2025
日本化学会北海道支部, 会計幹事 - Apr. 2020 - Mar. 2022
応用物理学会:有機分子・バイオエレクトロニクス分科会, 常任幹事, Society - Oct. 2017 - Sep. 2019
JSAP Multidisciplinary Young Researcher Chapter, 代表, Society - Apr. 2016 - Mar. 2018
応用物理学会:有機分子・バイオエレクトロニクス分科会, 常任幹事, Society - Apr. 2015 - Mar. 2016
応用物理学会:有機分子・バイオエレクトロニクス分科会, 幹事, Society
Research activity information
■ Awards- Feb. 2024, プラズモニック化学研究会, 若手奨励賞最優秀賞
- Oct. 2023, 株式会社リバネス, Tech Planter 最優秀賞
龍崎奏 - Oct. 2023, 大日本印刷株式会社, Tech Planter DNP賞
龍崎奏 - May 2023, Royal Society of Chemistry, and The Society of Nano Science and Technology, Nanoscale Horizons Award
Sou Ryuzaki - Feb. 2023, 北海道未来創造スタートアップ育成相互支援ネットワーク, HSFC Demo Day 優秀賞
龍崎奏 - Apr. 2022, 科学技術振興機構CREST[細胞外微粒子], Young Innovator Award
- Jul. 2021, DV-Xα研究協会, 奨励賞
- Dec. 2017, IOP Publishing, Nanotechnology, Highlights of 2017
- Aug. 2017, 9th International Conference on Molecular Electronics and Bioelectronics, The Best Poster Award
- Mar. 2016, 第63回応用物理学会春季学術講演会, 講演奨励賞
- Oct. 2010, 財団法人手島工業教育資金団, 手島記念博士論文賞
- Mar. 2007, 東京工業大学原子核工学専攻., 最優秀論文発表賞
- Glomerular routing of tumor-derived extracellular vesicles substantiates urinary biopsy.
Shota Kawaguchi; Taiga Ajiri; Rina Mitsuya; Reiko Tsuchiya; Koki Kunitake; Yoshikazu Tanaka; Takeshi Yokoyama; Kiichi Sato; Yusuke Sato; Zetao Zhu; Kunanon Chattrairat; Yasuko Kobayashi; Kimiko Inoue; Keisuke Imaeda; Kosei Ueno; Sou Ryuzaki; Akira Kato; Yasuyuki Kimura; Atsushi Natsume; Ryosuke Kojima; Takao Yasui
Science advances, 12, 8, eaeb0555, 20 Feb. 2026, [International Magazine]
English, Scientific journal, Urinary small extracellular vesicles (sEVs), which can reflect systemic conditions, hold great promise for noninvasive cancer diagnostics, yet the mechanism by which tumor-derived sEVs reach urine remains unclear. Here, we demonstrate that the glomerulus actively transcytoses circulating tumor-derived sEVs into urine. Using CRISPR guide RNA-tagged glioma sEVs and bioluminescent/fluorescent green-enhanced nano-lantern (GeNL)-tagged lung and pancreatic cancer sEVs, we tracked their journey from tumors to urine in multiple mouse models. In vivo and in vitro analyses revealed endocytic uptake and transcytotic release by glomerular cells, accompanied by changes in sEV size and surface composition. GeNL-tagged sEVs consistently showed higher signals in urine than plasma, indicating selective excretion. These findings redefine the glomerulus as a dynamic regulator of sEV processing and establish a mechanistic foundation for urinary liquid biopsy. - Plasmon-Enhanced Photoluminescence of Interlayer Excitons Induced on WSe2/MoS2 Heterobilayers
Keisuke Imaeda; Yusuke Takahashi; Shimba Ushikoshi; Takahiko Endo; Yasumitsu Miyata; Kosuke Nagashio; Sou Ryuzaki; Kosei Ueno
The Journal of Physical Chemistry Letters, 12 Feb. 2026
Scientific journal - Gap-Controlled Plasmon Dephasing and Near-Field Confinement in Metal–Insulator–Metal Nanostructures
Hiroki Takeuchi; Xiongjunyi Qian; Xiao-Tong Pan; Keisuke Imaeda; Sou Ryuzaki; Kosei Ueno
The Journal of Physical Chemistry C, 11 Dec. 2025
Scientific journal - High-Q Plasmonic Nanocavities Enabled by Integration of Au Nanogap Dimers with a Distributed Bragg Reflector
Keisuke Imaeda; Rin Miyazaki; Sou Ryuzaki; Kosei Ueno
The Journal of Physical Chemistry C, 13 Mar. 2025
Scientific journal - Coherent acoustic vibrations of Au nanoblocks and their modulation by Al2O3 layer deposition
Keisuke Imaeda; Yuto Shikama; Shimba Ushikoshi; Satoshi Sakai; Sou Ryuzaki; Kosei Ueno
The Journal of Chemical Physics, 14 Apr. 2024
Scientific journal - Exploring Hybrid States and Their Ultrafast Dynamics in Exciton–Plasmon Strong Coupling Systems
Hiroki Takeuchi; Keisuke Imaeda; Sou Ryuzaki; Kosei Ueno
The Journal of Physical Chemistry C, 15 Feb. 2024
Scientific journal - Transient Nascent Adhesion at the Initial Stage of Cell Adhesion Visualized on a Plasmonic Metasurface
Shi Ting Lee; Thasaneeya Kuboki; Satoru Kidoaki; Yukiko Aida; Sou Ryuzaki; Koichi Okamoto; Yusuke Arima; Kaoru Tamada
Advanced NanoBiomed Research, 2100100, 2100100, Wiley, Jan. 2022
Scientific journal - Field effect control of translocation dynamics in surround-gate nanopores
Makusu Tsutsui; Sou Ryuzaki; Kazumichi Yokota; Yuhui He; Takashi Washio; Kaoru Tamada; Tomoji Kawai
Communications Materials, 2, 1, Dec. 2021
English, Scientific journal - Effect of chemically induced permittivity changes on the plasmonic properties of metal nanoparticles
Noboru Saito; Sou Ryuzaki; Yuta Tsuji; Yutaka Noguchi; Rintaro Matsuda; Pangpang Wang; Daisuke Tanaka; Yusuke Arima; Koichi Okamoto; Kazunari Yoshizawa; Kaoru Tamada
Communications Materials, 2, 1, Dec. 2021
English, Scientific journal - Rapid Discrimination of Extracellular Vesicles by Shape Distribution Analysis
Sou Ryuzaki; Takao Yasui; Makusu Tsutsui; Kazumichi Yokota; Yuki Komoto; Piyawan Paisrisarn; Noritada Kaji; Daisuke Ito; Kaoru Tamada; Takahiro Ochiya; Masateru Taniguchi; Yoshinobu Baba; Tomoji Kawai
Analytical Chemistry, 93, 18, 7037, 7044, 11 May 2021, [International Magazine]
English, Scientific journal - Layer Number-Dependent Enhanced Photoluminescence from a Quantum Dot Metamaterial Optical Resonator
Haruka Takekuma; Junfu Leng; Kazutaka Tateishi; Yang Xu; Yinthai Chan; Sou Ryuzaki; Pangpang Wang; Koichi Okamoto; Kaoru Tamada
ACS Applied Electronic Materials, 3, 1, 468, 475, 26 Jan. 2021
English, Scientific journal - High Axial and Lateral Resolutions on Self-Assembled Gold Nanoparticle Metasurfaces for Live-Cell Imaging
Shihomi Masuda; Thasaneeya Kuboki; Satoru Kidoaki; Shi Ting Lee; Sou Ryuzaki; Koichi Okamoto; Yusuke Arima; Kaoru Tamada
ACS Applied Nano Materials, 3, 11, 11135, 11142, American Chemical Society ({ACS}), 25 Nov. 2020
Scientific journal - Pore Structures for High-Throughput Nanopore Devices
Sou Ryuzaki; Rintaro Matsuda; Masateru Taniguchi
Micromachines, 11, 10, 893, 893, Sep. 2020, [International Magazine]
English, Scientific journal - Flexibly tunable surface plasmon resonance by strong mode coupling using a random metal nanohemisphere on mirror
Okamoto, K.; Okura, K.; Wang, P.; Ryuzaki, S.; Tamada, K.
Nanophotonics, 9, 10, 3409, 3418, 2020
Scientific journal - Finite-difference time-domain simulations of inverted cone-shaped plasmonic nanopore structures
Matsuda, R.; Ryuzaki, S.; Okamoto, K.; Arima, Y.; Tsutsui, M.; Taniguchi, M.; Tamada, K.
Journal of Applied Physics, 127, 24, 2020
Scientific journal - Tuning the Emission Colors of Self-Assembled Quantum Dot Monolayers via One-Step Heat Treatment for Display Applications
Leng, J.; Xu, Y.; Chan, Y.; Wang, P.; Ryuzaki, S.; Okamoto, K.; Tamada, K.
ACS Applied Nano Materials, 3, 4, 3214, 3222, American Chemical Society ({ACS}), 2020
Scientific journal - Comparison of the mechanical strength of a monolayer of silver nanoparticles both in the freestanding state and on a soft substrate
Wang, P.; Ryuzaki, S.; Gao, L.; Shinohara, S.; Saito, N.; Okamoto, K.; Tamada, K.; Yamada, S.
Journal of Applied Physics, 125, 13, 2019
English, Scientific journal - Micro-photoluminescence mapping of light emissions from aluminum-coated InGaN/GaN quantum wells
Tateishi, K.; Wang, P.; Ryuzaki, S.; Funato, M.; Kawakami, Y.; Okamoto, K.; Tamada, K.
Applied Physics Express, 12, 5, 2019
English, Scientific journal - How to make microscale pores on a self-assembled Ag nanoparticle monolayer
Takekuma, H.; Tagomori, K.; Shinohara, S.; Masuda, S.; Xu, Y.; Chan, Y.; Wang, P.; Ryuzaki, S.; Okamoto, K.; Tamada, K.
Colloids and Interface Science Communications, 30, 2019
English, Scientific journal - Comparison of LSPR-mediated enhanced fluorescence excited by S- and P-polarized light on a two-dimensionally assembled silver nanoparticle sheet
Ishijima, A.; Wang, P.; Ryuzaki, S.; Okamoto, K.; Tamada, K.
Applied Physics Letters, 113, 17, 2018
Scientific journal - Surface plasmon resonance effect of silver nanoparticles on the enhanced efficiency of inverted hybrid organic-inorganic solar cell
Wulandari, P.; Handayani, Y.S.; Hidayat, R.; Wang, P.; Ryuzaki, S.; Okamoto, K.; Tamada, K.
Journal of Nonlinear Optical Physics and Materials, 27, 2, 2018
English, Scientific journal - Durability improvements of two-dimensional metal nanoparticle sheets by molecular cross-linked structures between nanoparticles
Saito, N.; Ryuzaki, S.; Wang, P.; Park, S.; Sakai, N.; Tatsuma, T.; Okamoto, K.; Tamada, K.
Japanese Journal of Applied Physics, 57, 3, 2018
English, Scientific journal - Micro-photoluminescence mapping of surface plasmon enhanced light emissions from InGaN/GaN quantum wells
Tateishi, K.; Wang, P.; Ryuzaki, S.; Funato, M.; Kawakami, Y.; Okamoto, K.; Tamada, K.
Applied Physics Letters, 111, 17, 2017
English, Scientific journal - Rapid structural analysis of nanomaterials in aqueous solutions
Ryuzaki, S.; Tsutsui, M.; He, Y.; Yokota, K.; Arima, A.; Morikawa, T.; Taniguchi, M.; Kawai, T.
Nanotechnology, 28, 15, 155501, 155501, 2017, [International Magazine]
English, Scientific journal - Photoexcited carrier dynamics in organic solar cells
Ryuzaki, S.; Onoe, J.
Organic Solar Cells: Materials, Devices, Interfaces, and Modeling, 2017
Scientific journal - Graphene-Au nanoparticle based vertical heterostructures: A novel route towards high-ZT Thermoelectric devices
Juang, Z.-Y.; Tseng, C.-C.; Shi, Y.; Hsieh, W.-P.; Ryuzaki, S.; Saito, N.; Hsiung, C.-E.; Chang, W.-H.; Hernandez, Y.; Han, Y.; Tamada, K.; Li, L.-J.
Nano Energy, 38, 385, 391, 2017
Scientific journal - Large patternable metal nanoparticle sheets by photo/e-beam lithography
Saito, N.; Wang, P.; Okamoto, K.; Ryuzaki, S.; Tamada, K.
Nanotechnology, 28, 43, 435705, 435705, 2017, [Peer-reviewed], [International Magazine]
English, Scientific journal - High-resolution imaging of a cell-attached nanointerface using a gold-nanoparticle two-dimensional sheet
Masuda, S.; Yanase, Y.; Usukura, E.; Ryuzaki, S.; Wang, P.; Okamoto, K.; Kuboki, T.; Kidoaki, S.; Tamada, K.
Scientific Reports, 7, 1, 3720, 3720, 2017, [Peer-reviewed], [International Magazine]
English, Scientific journal - Electrical trapping mechanism of single-microparticles in a pore sensor
Arima, A.; Tsutsui, M.; He, Y.; Ryuzaki, S.; Taniguchi, M.
AIP Advances, 6, 11, 2016
English, Scientific journal - Electromagnetically induced transparency of a plasmonic metamaterial light absorber based on multilayered metallic nanoparticle sheets
Okamoto, K.; Tanaka, D.; Degawa, R.; Li, X.; Wang, P.; Ryuzaki, S.; Tamada, K.
Scientific Reports, 6, 36165, 36165, 2016, [International Magazine]
English, Scientific journal - Silver nanoparticles with tunable work functions
Wang, P.; Tanaka, D.; Ryuzaki, S.; Araki, S.; Okamoto, K.; Tamada, K.
Applied Physics Letters, 107, 15, 2015
English, Scientific journal - Local charge transport properties of hydrazine reduced monolayer graphene oxide sheets prepared under pressure condition
Ryuzaki, S.; Meyer, J.A.S.; Petersen, Sø.; Nørgaard, K.; Hassenkam, T.; Laursen, B.W.
Applied Physics Letters, 105, 9, 2014
English, Scientific journal - Graphene/hexagonal boron nitride/graphene nanopore for electrical detection of single molecules
He, Y.; Tsutsui, M.; Ryuzaki, S.; Yokota, K.; Taniguchi, M.; Kawai, T.
NPG Asia Materials, 6, 6, 2014
English, Scientific journal - Anomaly in the electric resistivity of one-dimensional uneven peanut-shaped C
60 polymer film at a low temperature
Ryuzaki, S.; Onoe, J.
Applied Physics Letters, 104, 11, 2014
Scientific journal - Basic aspects for improving the energy conversion efficiency of hetero-junction organic photovoltaic cells
Sou Ryuzaki; Jun Onoe
NANO REVIEWS & EXPERIMENTS, 4, 1, 2013, [International Magazine]
English, Scientific journal - High speed DNA denaturation using microheating devices
Furuhashi, M.; Okamoto, Y.; Onoshima, D.; Ohshiro, T.; Ryuzaki, S.; Yokota, K.; Tsutsui, M.; Taniguchi, M.; Nakatani, K.; Baba, Y.; Kawai, T.
Applied Physics Letters, 103, 2, 2013
English, Scientific journal - In situ nondestructive impedance spectroscopic study of nanostructured heterojunction organic photovoltaic cells
Ryuzaki, S.; Onoe, J.
Japanese Journal of Applied Physics, 52, 6 PART 2, 2013
English, Scientific journal - Trapping and identifying single-nanoparticles using a low-aspect-ratio nanopore
Tsutsui, M.; Maeda, Y.; He, Y.; Hongo, S.; Ryuzaki, S.; Kawano, S.; Kawai, T.; Taniguchi, M.
Applied Physics Letters, 103, 1, 2013
English, Scientific journal - Electron transport properties of air-exposed one-dimensional uneven peanut-shaped C
60 polymer films
Ryuzaki, S.; Nishiyama, M.; Onoe, J.
Diamond and Related Materials, 33, 12, 15, 2013
English, Scientific journal - Photo-generated carrier dynamics in the vicinity of the donor/acceptor interface of organic solar cells
Ryuzaki, S.; Onoe, J.
IEEJ Transactions on Electronics, Information and Systems, 132, 8, 1, 8, 2012
English, Scientific journal - Influence of charge accumulation of photogenerated carriers in the vicinity of donor/acceptor interface on the open-circuit voltage of zinc-porphyrin/ C
60 heterojunction organic photovoltaic cells
Ryuzaki, S.; Onoe, J.
Journal of Physics D: Applied Physics, 44, 26, 2011
English, Scientific journal - Effects of inter-molecular charge-transfer excitons on the external quantum efficiency of zinc-porphyrin/C
60 heterojunction photovoltaic cells
Ryuzaki, S.; Kai, T.; Toda, Y.; Adachi, S.; Onoe, J.
Journal of Physics D: Applied Physics, 44, 14, 2011
English, Scientific journal - X-ray diffraction and infrared multiple-angle incidence resolution spectroscopic studies on the crystal structure and molecular orientation of zinc-porphyrin thin films on a SiO
2 /Si substrate
Ryuzaki, S.; Hasegawa, T.; Onoe, J.
Journal of Applied Physics, 105, 11, 2009
Scientific journal - X-ray diffraction and scanning electron microscopic studies on the crystal structure and surface/interface morphology of zinc-octaethylporphyrin films on an indium tin oxide substrate spin coated with 3,4-polyethylenedioxythiophene: polystyrenesulfonate
Ryuzaki, S.; Onoe, J.
Journal of Applied Physics, 106, 2, 2009
Scientific journal - The crystallinity and surface morphology of zinc octaethylporphyrin thin films on an indium-tin-oxide substrate
Ryuzaki, S.; Onoe, J.
Journal of Applied Physics, 103, 3, 2008
Scientific journal - Femtosecond carrier dynamics in electron-beam-irradiated C60 film
Toda, Y.; Ryuzaki, S.; Onoe, J.
Applied Physics Letters, 92, 9, 2008
Scientific journal - In situ X-ray photoelectron spectroscopic study of metalloporphyrin- fullerene alternative-deposited thin films
Ryuzaki, S.; Ishii, T.; Onoe, J.
Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers, 46, 8 A, 5363, 5366, INSTITUTE OF PURE AND APPLIED PHYSICS, 2007
English, Scientific journal
- EVs : 細胞外小胞の生物学 : エクソソームをはじめとする多様な小胞の生理・病理の理解と新しい解析法
中野, 明彦; 吉森, 保; 華山, 力成
羊土社, Dec. 2021, 9784758103992, 207p, Japanese, [Contributor] - 化学75-5月号「注目の論文:エクソソームの表面タンパク質を見分ける」
龍崎奏
May 2020, [Contributor] - Organic Solar Cells : Materials, Devices, Interfaces, and Modeling
Sou Ryuzaki
Dec. 2017, [Contributor]
- Fabrication of nanopore devices for Exosomes
Sou Ryuzaki
35th International Microprocesses and Nanotechnology Conference, 08 Nov. 2022, English, Invited oral presentation
08 Nov. 2022 - 11 Nov. 2022, [Invited]
■ Affiliated academic society
- 2022 - Present
日本化学会 - 2021 - Present
日本分析化学会 - 2021 - Present
American Chemical Society - 2005 - Present
DV-Xα研究協会 - 2005 - Present
ナノ学会 - 2005 - Present
応用物理学会
- A Study of Viral Material Engineering
Grants-in-Aid for Scientific Research
01 Apr. 2025 - 31 Mar. 2030
谷口 正輝; 龍崎 奏
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (S), The University of Osaka, 25H00418 - プラズモニックナノ構造と機械学習を用いたmiRNA分布識別法の開発
科学研究費助成事業
01 Apr. 2025 - 31 Mar. 2028
龍崎 奏
日本学術振興会, 基盤研究(C), 北海道大学, 25K08449 - Development of a single particle analysis platform and a comprehensive understanding of the diversity of bacterial membrane vesicles
Grants-in-Aid for Scientific Research
01 Apr. 2024 - 31 Mar. 2027
田代 陽介; 龍崎 奏; 横山 文秋
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B), Shizuoka University, 24K01666 - Biosensor based on surface molecular information of extracellular vesicles
Grants-in-Aid for Scientific Research
01 Apr. 2022 - 31 Mar. 2025
龍崎 奏; 馬場 英司
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B), Hokkaido University, 23K23195 - Biosensor based on surface molecular information of extracellular vesicles
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
01 Apr. 2022 - 31 Mar. 2025
龍崎 奏; 馬場 英司
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B), Hokkaido University, 22H01927 - Metal multi-nanopore structures for quantum dot lasing
Grants-in-Aid for Scientific Research
01 Apr. 2019 - 31 Mar. 2022
Ryuzaki Sou
A novel laser has been developed by metal multi-nanopore structure with a diameter of ca.100 nm filled with a solution in which quantum dots (QDs) are dispersed. The Fabry-Perot type lasing is caused by plasmonic resonances between the emission from QDs and the metal multi-nanopore structure. In this study, the following results have been mainly achieved. (1) Development of a method to control the emission characteristics of quantum dots after synthesis, (2) Fabrication and characterization of plasmonic nanopores, (3) Revealing the correlation between electronic state at the metal-organic interface and plasmon resonance properties, (4) Fabry-Perot type lasing by the metal multi-nanopore structure.
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C), Kyushu University, 19K05234 - Exosome analysis device for cancer early diagnosis
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)
01 Apr. 2016 - 31 Mar. 2020
Baba Yoshinobu
Exosomes are extracellular vesicles and play an important role for cancer tumorigenesis, cancer progression, and cancer metastasis. And, exosomes have more information than conventional blood biomarkers. Recently, researchers expected exosomes as the next-generation cancer diagnosis biomarkers. In this research, we proposed a device to demonstrate rapid and precise analysis of cancer specific exosomes using nanospace unique features. And furthermore, we had a goal to aim for cancer diagnosis system, which could achieve higher speed and more accurate diagnosis than conventional systems.
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A), Nagoya University, 16H02091 - 形状と組成情報に基づく1粒子解析技術の開発
戦略的な研究開発の推進 戦略的創造研究推進事業 さきがけ
2017 - 2020
龍崎 奏
本研究では、液中に浮遊している微粒子の「形状情報」と「組成情報」を同時に計測する革新的1粒子解析技術の開発をねらいとしています。生体微粒子において、「形状」と「組成」の相関性を解明することは、その微粒子の機能解明へと繋がります。本研究では、がん転移の指向性などに関わっているとされているエクソソームの「形状」と「組成」の相関性を明らかにし、構造的な観点からエクソソームの機能解析を目指します。
科学技術振興機構, 九州大学 - Nanopore devices for structural analysis of nanobio materials
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A)
01 Apr. 2015 - 31 Mar. 2018
Ryuzaki sou; TANIGUCHI Masateru
Rapid structural analysis of nanoscale matter in a liquid environment represents innovative technologies that reveal the identities and functions of biologically important molecules. However, there is currently no method with high spatio-temporal resolution that can scan individual particles in solutions to gain structural information. Here we report the development of a nanopore platform realizing quantitative structural analysis for suspended nanomaterials in solutions. We used a low thickness-to-diameter aspect ratio pore architecture for achieving cross sectional areas of analyte (i.e. tomograms). Combining this with multiphysics simulation methods to translate ionic current data into tomograms, we demonstrated rapid structural analysis of many kind of single vesicles and EVs. The present results indicate this structural analysis is very powerful tool to identify nano-bioparticles and have a potential as novel nanobio sensors from the view point of particle shapes.
Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (A), Kyushu University, 15H05417 - Complex 3D nanometamaterials composed of self-assembled metal nanoparticles
Grants-in-Aid for Scientific Research
01 Apr. 2014 - 31 Mar. 2018
Tamada Kaoru; OKAMOTO Koichi; RYUZAKI Sou; WANG Pangpang; PARK Cheomin; WULANDARI Pristuti; LI Lain-Jong; CRAIG S. J. Vincent; CHAN Yin Thai; YANG Xu
This study aimed at multidimensional self-assembly of metallic nanoparticles, and theoretical and experimental elucidation of novel optical phenomena developed in this study, and development of novel nano-optical devices using these phenomena. The main scientific achievement is to reveal the origin of color change observed on multidimensional self-assembled metal nanoparticle sheets on a metal substrate, as "electromagnetically induced transparency (EIT)". The main achievements in application are
development of colorimetric sensors by use of EIT and super resolution imaging of cell attached nano interface. These our original studies disseminate the fundamental field of plasmonic and nanometamaterials to the world.
Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A), Kyushu University, 26246005 - Nanopore devices for a structural analysis of single molecules
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
01 Apr. 2013 - 31 Mar. 2015
RYUZAKI Sou
Nanopore devices consisting of a surround gating electrode causing a decrease in speed of nanomaterials passing through the nanopore have been fabricated in order to analyze structures of the materials. The gating voltage via a gating electrode resulted in 240 times slower speed of nanoparticles passing through a nanopore than that without the gating voltage, and DNA also showed 10 times slower speed under the gating voltage. In addition, the shapes and structures of these materials passing through a nanopore were quantitatively revealed by analysing changes in ionic current due to the material translation.
Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B), Kyushu University, 25790029
Social Contribution Activities
- 日本分析化学会第74年会
24 Sep. 2025 - 26 Sep. 2025
Organizing member - ASIANALYSIS XVII 2025
23 Sep. 2025 - 26 Sep. 2025
Organizing member - 応用物理学会シンポジウム「宇宙開発を支えるバイオデバイス科学の最前線」
09 Sep. 2025 - 09 Sep. 2025
Organizing member - KJF-ICOMEP 2023
30 Aug. 2023 - 02 Sep. 2023
Organizing member
