Researcher basic information

• Doctor of Philosophy, Hokkaido University

• https://researchmap.jp/read0150067?lang=en

• https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201001099728627820
• http://www.eng.hokudai.ac.jp/labo/risk/

• 60604692

• 201001099728627820

• 水道
• 水道水質基準
• 水質ガイドライン
• 浄水処理
• 新規凝集剤
• 新規吸着材
• 膜ろ過
• セラミック膜
• 水系感染症
• 病原ウイルス
• アデノウイルス
• アストロウイルス
• ノロウイルス
• サポウイルス
• エンテロウイルス
• コクサッキーウイルス
• エコーウイルス
• パレコウイルス
• A型肝炎ウイルス
• E型肝炎ウイルス
• ロタウイルス
• トウガラシ微斑ウイルス
• 大腸菌ファージ
• 新規ウイルス濃縮法
• 新規ウイルス定量法
• 遺伝的多様性
• 細胞培養
• リバースジェネティクス法
• ウイルス除去
• ウイルス不活化

• Social Infrastructure (Civil Engineering, Architecture, Disaster Prevention), Environmental systems for civil engineering
• Environmental Science/Agriculture Science, Environmental load and risk assessment
• Environmental Science/Agriculture Science, Environmental load reduction and remediation

• Bachelor's degree program, School of Engineering
• Master's degree program, Graduate School of Engineering
• Doctoral (PhD) degree program, Graduate School of Engineering

Research activity information

• 2025, 2025年度公益信託エスペック地球環境研究・技術基金 (エスペック環境研究奨励賞)
  白崎伸隆
• 2024, 令和6年度北海道科学技術奨励賞 (知事表彰)
  白崎伸隆
• 2024, 第61回環境工学研究フォーラム 優秀ポスター発表賞
  福井健暉, 白崎伸隆, 松下拓, 松井佳彦
• 2024, 第61回環境工学研究フォーラム 優秀ポスター発表賞
  浅川高志, 白崎伸隆, 松下拓, 松井佳彦
• 2024, 第61回環境工学研究フォーラム 環境技術・プロジェクト賞
  白崎伸隆;浅川高志;福井健暉;松下拓
• 2024, 2024年度堀場雅夫賞
  白崎伸隆
• 2024, 令和5年度日本水環境学会 論文賞
  白崎伸隆
• 2023, 第60回環境工学研究フォーラム 優秀ポスター発表賞
  白崎伸隆, 胡秋晗, 白川大樹, 高木弘隆, 岡智一郎, 松下拓, 松井佳彦
• 2023, 第7回バイオインダストリー奨励賞
  白崎伸隆
• 2023, 令和5年度河川財団奨励賞
  白崎伸隆
• 2022, Best Poster Award at the IWA World Water Congress and Exhibition 2022
  Matsushita, T.;Sugita, W.;Ishikawa, T.;Shi, G.;Nishizawa, S.;Matsui, Y.;Shirasaki, N.
• 2021, 北海道大学大学院工学研究院 若手教員奨励賞
  白崎伸隆
• 2021, 遠山椿吉記念 第7回食と環境の科学賞 山田和江賞
  白崎伸隆
• 2019, 平成30年度建設工学研究振興会 建設工学研究奨励賞
  白崎伸隆
• 2017, 平成29年度クリタ水・環境科学研究優秀賞
  白崎伸隆
• 2016, Outstanding Contribution in Reviewing Award, Water Research (Elsevier)
  Nobutaka Shirasaki
• 2015, 平成26年度日本水環境学会 論文奨励賞 (廣瀬賞)
  白崎伸隆
• 2013, 土木学会平成25年度全国大会第68回年次学術講演会 優秀講演者表彰
  白崎伸隆
• 2013, 第2回エヌエフ基金 研究開発奨励賞 (環境・エネルギー)
  白崎伸隆
• 2013, 第49回環境工学研究フォーラム 論文賞
  白崎伸隆;松下拓;松井佳彦;大芝淳
• 2013, 平成25年度前田記念工学振興財団 設立20周年記念特別論文賞 最優秀賞
  白崎伸隆
• 2012, 平成24年度前田記念工学振興財団 山田一宇賞
  白崎伸隆, Japan
• 2012, 平成24年度文部科学大臣表彰 若手科学者賞
  白崎伸隆, Japan
• 2011, 平成22年度土木学会 論文奨励賞
  白崎伸隆, Japan
• 2010, 第46回環境工学研究フォーラム 論文奨励賞
  白崎伸隆, Japan
• 2009, 第12回日本水環境学会シンポジウム若手研究紹介（オルガノ）セッション 最優秀発表賞
  白崎伸隆, Japan
• 2009, 平成21年度日本水環境学会 博士研究奨励賞（オルガノ賞）
  白崎伸隆, Japan
• 2008, 第45回環境工学研究フォーラム 優秀ポスター発表賞
  白崎伸隆;浦崎稔史;小泓誠;松下拓;松井佳彦;大野浩一, Japan
• 2005, 平成16年度土木学会中部支部 優秀研究発表賞
  白崎伸隆
• 2005, 岐阜大学工学部土木工学科 平成16年度優秀卒業研究賞
  白崎伸隆
• 2005, 岐阜大学工学部 総代
  白崎伸隆
• 2003, 全国高等専門学校土木工学会 近藤賞
  白崎伸隆

• Application of viability PCR to investigate the capsid integrity of human enteric viruses in drinking water sources and the persistence of those viruses in surface waters.
  Daiki Shirakawa; Nobutaka Shirasaki; Satoshi Koriki; Taku Matsushita; Yoshihiko Matsui
  Science of the total environment, 1028, 181718, 181718, 27 Mar. 2026, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Here, we investigated the occurrence of indigenous human enteric viruses with intact capsids (i.e., those that are potentially infectious) in drinking water sources by applying viability PCR using improved propidium monoazide with an enhancer (PMAxx-Enhancer-PCR). A comparison of the results obtained with PCR alone and PMAxx-Enhancer-PCR suggested that adenovirus, norovirus GI, and rotavirus present in drinking water sources tended to have damaged capsids and be inactivated by damage to the capsid. In contrast, astrovirus, norovirus GII, and enteroviruses tended to have intact capsids and be potentially infectious. To elucidate the main cause of damage to the viral capsid, we next investigated the effects of environmental stresses (water temperature, particulate matter, enzymatic activity, and sunlight) on viral persistence in surface waters used as drinking water sources through virus-spiking incubation experiments by using infectivity assays, PCR alone, and PMAxx-Enhancer-PCR. The pseudo-first-order decay rate constants of the viruses obtained with PMAxx-Enhancer-PCR were comparable to those obtained with PCR alone when only water temperature, particulate matter, and enzymatic activity were stresses. In contrast, when sunlight was present in addition to the other three stresses, PMAxx-Enhancer-PCR showed larger decay rate constants than PCR alone. Thus, sunlight appears to be an environmental stress that determines the capsid integrity of indigenous human enteric viruses in drinking water sources. Indigenous pepper mild mottle virus (PMMoV) was present at >100 times higher concentrations in drinking water sources than human enteric viruses in both cases of using PCR alone and PMAxx-Enhancer-PCR, supporting the suitability of PMMoV as a surrogate for human enteric viruses for evaluating virus removal in actual drinking water treatment plants. The incubation experiments suggested that PMMoV is more resistant to environmental stresses than human enteric viruses, partly due to its more robust capsid structure. This may contribute to the high concentration of PMMoV in drinking water sources.
• Methomyl, a carbamate insecticide, forms oxygenated transformation products that inhibit acetylcholinesterase upon chlorination.
  Taku Matsushita; Sotaro Hirata; Nobutaka Shirasaki; Yoshihiko Matsui
  Water research, 285, 124068, 124068, 20 Jun. 2025, [Peer-reviewed], [International Magazine]
  English, Scientific journal, The fates of organophosphorus insecticides during chlorination, a widely used disinfection step in drinking water treatment, have been extensively investigated. These compounds are known to partly transform into their corresponding "oxons", which retain the same mode of action-the inhibition of acetylcholinesterase (AChE)-as their parent compounds, but with markedly greater potency. In contrast, although carbamate insecticides share the same mode of action, their toxicological fates during chlorination remain entirely unexplored. Here, we investigated changes in anti-AChE activity during chlorination of a solution containing methomyl, a carbamate insecticide. The activity was assessed in the presence (indirect toxicity) and absence (direct toxicity) of metabolic activation. Methomyl reacted with free chlorine and almost completely disappeared at a chlorine-to-compound molar ratio of ≥4. Even so, the chlorinated samples retained both direct and indirect toxicities. Indirect toxicity was attributable solely to residual methomyl. Direct toxicity originated from residual methomyl and the TPs methomyl-sulfoxide and a dioxygenated derivative of methomyl-sulfoxide. No other TPs contributed to it. Methomyl-sulfoxide was identified via MS/MS spectral matching, but the dioxygenated TP could not be structurally confirmed. From a toxicological perspective, drinking water treatment plants using free chlorine for disinfection should monitor at least methomyl-sulfoxide in addition to methomyl in finished water.
• Decomposition in vacuum ultraviolet-based advanced oxidation/reduction processes and its relationship to physicochemical properties of target contaminants.
  Taiyo Akuto; Long Pan; Taku Matsushita; Rinako Kawashita; Yoshihiko Matsui; Nobutaka Shirasaki
  Science of the Total Environment, 986, 179784, 179784, 31 May 2025, [Peer-reviewed], [International Magazine]
  English, Scientific journal, Vacuum ultraviolet (VUV)-based treatment for water supplies can potentially be applied to a wide range of compounds because they enable enhancement of either oxidative or reductive decomposition through the addition of ozone (O3) or the reduction of dissolved oxygen (DO), respectively. In the present study, we applied three VUV-based treatments (VUV alone, VUV/O3, and VUV/low-DO) to five ozone-resistant compounds (1,4-dioxane, epichlorohydrin, acephate, N-nitrosodimethylamine [NDMA], and dichloroacetonitrile [DCAN]), and evaluated the extent of oxidative and reductive enhancements for each contaminant. Simple correlation analysis revealed that oxidative and reductive enhancements were more effective for compounds with a high highest occupied molecular orbital (HOMO) energy level and low lowest unoccupied molecular orbital (LUMO) energy level, respectively. These findings suggested that the effective VUV-based treatment for a contaminant might be identified by simply calculating its HOMO and LUMO energy levels. Further optimizations of O3 and DO concentrations reduced the electric energy per order values for epichlorohydrin and DCAN to approximately 4/5 and 1/3, respectively, of their values for VUV alone.
• Chlorine-substituted transformation products generated during chlorination of the organophosphorus insecticide disulfoton induce anti-acetylcholine esterase activity
  Taku Matsushita; Daisuke Ando; Nobutaka Shirasaki; Trang My Chu; Karen Ozaki; Yoshihiko Matsui
  Chemosphere, 372, Mar. 2025, [Peer-reviewed]
  Scientific journal
• Investigation of removal and inactivation efficiencies of human sapovirus in drinking water treatment processes by applying an in vitro cell-culture system
  D. Shirakawa; N. Shirasaki; Q. Hu; T. Matsushita; Y. Matsui; H. Takagi; T. Oka
  Water Research, 236, 01 Jun. 2023, [Peer-reviewed]
  Scientific journal
• Overlooked effect of ordinary inorganic ions on polyaluminum-chloride coagulation treatment
  Yize Chen; Yoshihiko Matsui; Tsutomu Sato; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 235, 15 May 2023, [Peer-reviewed]
  Scientific journal
• Screening priority pesticides for drinking water quality regulation and monitoring by machine learning: Analysis of factors affecting detectability
  Kentaro Narita; Yoshihiko Matsui; Taku Matsushita; Nobutaka Shirasaki
  Journal of Environmental Management, 326, 15 Jan. 2023, [Peer-reviewed]
  Scientific journal
• Suppressing transmembrane-pressure rise by pulse dosing of submicron super-fine powdered activated carbon: Effects of filtration flux, coagulant types, and coagulant-dose timing during precoating
  Yuanjun Zhao; Yoshihiko Matsui; Yusuke Kinouchi; Takumu Seko; Nobutaka Shirasaki; Taku Matsushita
  Journal of Water Process Engineering, 49, Oct. 2022, [Peer-reviewed]
  Scientific journal
• Factors affecting the catalytic oxidative removal of soluble manganese in natural water by superfine powdered activated carbon and free chlorine
  Shun Saito; Yoshihiko Matsui; Nobutaka Shirasaki; Taku Matsushita
  Journal of Water Process Engineering, 49, Oct. 2022, [Peer-reviewed]
  Scientific journal
• Effectiveness of pulse dosing of submicron super-fine powdered activated carbon in preventing transmembrane pressure rise in outside-in-type tubular and inside-out-type monolithic ceramic membrane microfiltrations
  Yuanjun Zhao; Yoshihiko Matsui; Shun Saito; Nobutaka Shirasaki; Taku Matsushita
  Separation and Purification Technology, 296, 01 Sep. 2022, [Peer-reviewed]
  Scientific journal
• Removal of soluble divalent manganese by superfine powdered activated carbon and free chlorine: Development and application of a simple kinetic model of mass transfer–catalytic surface oxidation
  Shun Saito; Yoshihiko Matsui; Nobutaka Shirasaki; Taku Matsushita
  Water Research X, 16, 01 Aug. 2022, [Peer-reviewed]
  Scientific journal
• Evaluation of reduction efficiencies of pepper mild mottle virus and human enteric viruses in full-scale drinking water treatment plants employing coagulation-sedimentation–rapid sand filtration or coagulation–microfiltration
  D. Shirakawa; N. Shirasaki; T. Matsushita; Y. Matsui; R. Yamashita; T. Matsumura; S. Koriki
  Water Research, 213, Apr. 2022, [Peer-reviewed]
  Scientific journal
• Desorption of micropollutant from superfine and normal powdered activated carbon in submerged-membrane system due to influent concentration change in the presence of natural organic matter: Experiments and two-component branched-pore kinetic model
  Long Pan; Akiko Nakayama; Yoshihiko Matsui; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 208, 01 Jan. 2022, [Peer-reviewed]
  Scientific journal
• Metabolism-Coupled Cell-Independent Acetylcholinesterase Activity Assay for Evaluation of the Effects of Chlorination on Diazinon Toxicity
  Taku Matsushita; Yuji Kikkawa; Kei Omori; Yoshihiko Matsui; Nobutaka Shirasaki
  Chemical Research in Toxicology, 34, 9, 2070, 2078, 20 Sep. 2021, [Peer-reviewed]
  Scientific journal
• Differences in removal rates of virgin/decayed microplastics, viruses, activated carbon, and kaolin/montmorillonite clay particles by coagulation, flocculation, sedimentation, and rapid sand filtration during water treatment
  Yoshifumi Nakazawa; Taketo Abe; Yoshihiko Matsui; Koki Shinno; Sakiko Kobayashi; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 203, 15 Sep. 2021, [Peer-reviewed], [International Magazine]
  Scientific journal
• Corrigendum to ’Oxidative removal of soluble divalent manganese ion by chlorine in the presence of superfine powdered activated carbon’ [Water Research 187 (2020) 116412] (Water Research (2020) 187, (S0043135420309477), (10.1016/j.watres.2020.116412))
  Shun Saito; Yoshihiko Matsui; Yasuhiko Yamamoto; Shuhei Matsushita; Satoru Mima; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 202, 01 Sep. 2021, [Peer-reviewed], [International Magazine]
  Scientific journal
• Computational fluid dynamics–based modeling and optimization of flow rate and radiant exitance for 1,4-dioxane degradation in a vacuum ultraviolet photoreactor
  Gang Shi; Shota Nishizawa; Taku Matsushita; Yuna Kato; Takahiro Kozumi; Yoshihiko Matsui; Nobutaka Shirasaki
  Water Research, 197, 01 Jun. 2021, [Peer-reviewed], [International Magazine]
  Scientific journal
• Stray particles as the source of residuals in sand filtrate: Behavior of superfine powdered activated carbon particles in water treatment processes
  Yoshifumi Nakazawa; Taketo Abe; Yoshihiko Matsui; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 190, 15 Feb. 2021, [Peer-reviewed], [International Magazine]
  Scientific journal
• Selection of priority pesticides in Japanese drinking water quality regulation: Validity, limitations, and evolution of a risk prediction method
  Kentaro Narita; Yoshihiko Matsui; Taku Matsushita; Nobutaka Shirasaki
  Science of the Total Environment, 751, 10 Jan. 2021, [Peer-reviewed], [International Magazine]
  Scientific journal
• Oxidative removal of soluble divalent manganese ion by chlorine in the presence of superfine powdered activated carbon
  Shun Saito; Yoshihiko Matsui; Yasuhiko Yamamoto; Shuhei Matsushita; Satoru Mima; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 187, 15 Dec. 2020, [Peer-reviewed], [International Magazine]
  Scientific journal
• Effect of chlorination on anti-acetylcholinesterase activity of organophosphorus insecticide solutions and contributions of the parent insecticides and their oxons to the activity
  Taku Matsushita; Yuki Fujita; Kei Omori; Yuxiang Huang; Yoshihiko Matsui; Nobutaka Shirasaki
  Chemosphere, 261, Dec. 2020, [Peer-reviewed], [International Magazine]
  Scientific journal
• Suitability of pepper mild mottle virus as a human enteric virus surrogate for assessing the efficacy of thermal or free-chlorine disinfection processes by using infectivity assays and enhanced viability PCR
  N. Shirasaki; T. Matsushita; Y. Matsui; S. Koriki
  Water Research, 186, 01 Nov. 2020, [Peer-reviewed], [International Magazine]
  Scientific journal
• Formation of disinfection by-products from coexisting organic matter during vacuum ultraviolet (VUV) or ultraviolet (UV) treatment following pre-chlorination and their fates after post-chlorination
  Shota Nishizawa; Taku Matsushita; Yoshihiko Matsui; Nobutaka Shirasaki
  Science of the Total Environment, 737, 01 Oct. 2020, [Peer-reviewed], [International Magazine]
  Scientific journal
• Sulfate ion in raw water affects performance of high-basicity PACl coagulants produced by Al(OH)3 dissolution and base-titration: Removal of SPAC particles by coagulation-flocculation, sedimentation, and sand filtration
  Yize Chen; Yoshifumi Nakazawa; Yoshihiko Matsui; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 183, 15 Sep. 2020, [Peer-reviewed], [International Magazine]
  Scientific journal
• Effects of pre, post, and simultaneous loading of natural organic matter on 2-methylisoborneol adsorption on superfine powdered activated carbon: Reversibility and external pore-blocking
  Akiko Nakayama; Asuka Sakamoto; Taku Matsushita; Yoshihiko Matsui; Nobutaka Shirasaki
  Water Research, 182, 01 Sep. 2020, [Peer-reviewed], [International Magazine]
  Scientific journal
• Precoating membranes with submicron super-fine powdered activated carbon after coagulation prevents transmembrane pressure rise: Straining and high adsorption capacity effects
  Yuanjun Zhao; Ryosuke Kitajima; Nobutaka Shirasaki; Yoshihiko Matsui; Taku Matsushita
  Water Research, 177, 15 Jun. 2020, [Peer-reviewed], [International Magazine]
  Scientific journal
• Prediction of 1,4-dioxane decomposition during VUV treatment by model simulation taking into account effects of coexisting inorganic ions
  Taku Matsushita; Wataru Sugita; Tomoya Ishikawa; Gang Shi; S. Nishizawa; Yoshihiko Matsui; Nobutaka Shirasaki
  Water Research, 164, 01 Nov. 2019, [Peer-reviewed], [International Magazine]
  Scientific journal
• Assessment of indirect inhalation exposure to formaldehyde evaporated from water
  Shunto Nishikawa; Yoshihiko Matsui; Taku Matsushita; Nobutaka Shirasaki
  Regulatory Toxicology and Pharmacology, 106, 43, 49, Aug. 2019, [Peer-reviewed], [International Magazine]
  Scientific journal
• Micro-milling super-fine powdered activated carbon decreases adsorption capacity by introducing oxygen/hydrogen-containing functional groups on carbon surface from water
  Hideki Takaesu; Yoshihiko Matsui; Yuki Nishimura; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 155, 66, 75, 15 May 2019, [Peer-reviewed], [International Magazine]
  Scientific journal
• Minimizing residual black particles in sand filtrate when applying super-fine powdered activated carbon: Coagulants and coagulation conditions
  Yoshifumi Nakazawa; Yoshihiko Matsui; Yusuke Hanamura; Koki Shinno; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 147, 311, 320, 15 Dec. 2018, [Peer-reviewed], [International Magazine]
  Scientific journal
• Removals of pesticides and pesticide transformation products during drinking water treatment processes and their impact on mutagen formation potential after chlorination
  Taku Matsushita; Ayako Morimoto; Taisuke Kuriyama; Eisuke Matsumoto; Yoshihiko Matsui; Nobutaka Shirasaki; Takashi Kondo; Hirokazu Takanashi; Takashi Kameya
  Water Research, 138, 67, 76, 01 Jul. 2018, [Peer-reviewed], [International Magazine]
  Scientific journal
• Identifying, counting, and characterizing superfine activated-carbon particles remaining after coagulation, sedimentation, and sand filtration
  Yoshifumi Nakazawa; Yoshihiko Matsui; Yusuke Hanamura; Koki Shinno; Nobutaka Shirasaki; Taku Matsushita
  Water Research, 138, 160, 168, 01 Jul. 2018, [Peer-reviewed], [International Magazine]
  Scientific journal
• Monte-Carlo and multi-exposure assessment for the derivation of criteria for disinfection byproducts and volatile organic compounds in drinking water: Allocation factors and liter-equivalents per day
  Megumi Akiyama; Yoshihiko Matsui; Junki Kido; Taku Matsushita; Nobutaka Shirasaki
  Regulatory Toxicology and Pharmacology, 95, 161, 174, Jun. 2018, [Peer-reviewed], [International Magazine]
  Scientific journal
• Identification of mutagenic transformation products generated during oxidation of 3-methyl-4-nitrophenol solutions by orbitrap tandem mass spectrometry and quantitative structure–activity relationship analyses
  Taku Matsushita; Shiho Honda; Taisuke Kuriyama; Yuki Fujita; Takashi Kondo; Yoshihiko Matsui; Nobutaka Shirasaki; Hirokazu Takanashi; Takashi Kameya
  Water Research, 129, 347, 356, 01 Feb. 2018, [Peer-reviewed], [International Magazine]
  Scientific journal
• Evaluation of the suitability of a plant virus, pepper mild mottle virus, as a surrogate of human enteric viruses for assessment of the efficacy of coagulation–rapid sand filtration to remove those viruses
  N. Shirasaki; T. Matsushita; Y. Matsui; R. Yamashita
  Water Research, 129, 460, 469, 01 Feb. 2018, [Peer-reviewed], [International Magazine]
  Scientific journal
• Trichloramine Removal with Activated Carbon is Governed by Two Reductive Reactions: A Theoretical Approach with Diffusion-Reaction Models
  Taku Matsushita; Yoshihiko Matsui; Shohei Ikekame; Miki Sakuma; Nobutaka Shirasaki
  Environmental Science and Technology, 51, 8, 4541, 4548, Apr. 2017, [Peer-reviewed], [International Magazine]
  Scientific journal
• Elimination of representative contaminant candidate list viruses, coxsackievirus, echovirus, hepatitis A virus, and norovirus, from water by coagulation processes
  N. Shirasaki; T. Matsushita; Y. Matsui; K. Murai; A. Aochi
  Journal of Hazardous Materials, 326, 110, 119, 15 Mar. 2017, [Peer-reviewed], [International Magazine]
  Scientific journal
• Corrigendum to "Investigation of enteric adenovirus and poliovirus removal by coagulation processes and suitability of bacteriophages MS2 and φX174 as surrogates for those viruses" [Science of the Total Environment 563-564(2016) 29-39].
  N Shirasaki; T Matsushita; Y Matsui; T Marubayashi; K Murai
  Science of the Total Environment, 576, 472, 472, 15 Jan. 2017, [Peer-reviewed], [International Magazine]
  English, Scientific journal
• Characteristics and components of poly-aluminum chloride coagulants that enhance arsenate removal by coagulation: Detailed analysis of aluminum species
  Yoshihiko Matsui; Nobutaka Shirasaki; Takuro Yamaguchi; Kenta Kondo; Kaori Machida; Taiga Fukuura; Taku Matsushita
  Water Research, 118, 177, 186, 2017, [Peer-reviewed], [International Magazine]
  Scientific journal
• Effects of decreasing activated carbon particle diameter from 30 Μm to 140 nm on equilibrium adsorption capacity
  Long Pan; Yuki Nishimura; Hideki Takaesu; Yoshihiko Matsui; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 124, 425, 434, 2017, [Peer-reviewed], [International Magazine]
  Scientific journal
• Use of gas chromatography–mass spectrometry–olfactometry and a conventional flask test to identify off-flavor compounds generated from phenylalanine during chlorination of drinking water
  Taku Matsushita; Miki Sakuma; Shiori Tazawa; Taiki Hatase; Nobutaka Shirasaki; Yoshihiko Matsui
  Water Research, 125, 332, 340, 2017, [Peer-reviewed], [International Magazine]
  Scientific journal
• Micro-milling of spent granular activated carbon for its possible reuse as an adsorbent: Remaining capacity and characteristics
  Long Pan; Yuichi Takagi; Yoshihiko Matsui; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 114, 50, 58, 2017, [Peer-reviewed], [International Magazine]
  Scientific journal
• Assessment of the efficacy of membrane filtration processes to remove human enteric viruses and the suitability of bacteriophages and a plant virus as surrogates for those viruses
  N. Shirasaki; T. Matsushita; Y. Matsui; K. Murai
  Water Research, 115, 29, 39, 2017, [Peer-reviewed], [International Magazine]
  Scientific journal
• Superiority of wet-milled over dry-milled superfine powdered activated carbon for adsorptive 2-methylisoborneol removal
  Long Pan; Yoshihiko Matsui; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 102, 516, 523, 01 Oct. 2016, [Peer-reviewed], [International Magazine]
  Scientific journal
• Investigation of enteric adenovirus and poliovirus removal by coagulation processes and suitability of bacteriophages MS2 and φX174 as surrogates for those viruses
  N. Shirasaki; T. Matsushita; Y. Matsui; T. Marubayashi; K. Murai
  Science of the Total Environment, 563-564, 29, 39, 01 Sep. 2016, [Peer-reviewed], [International Magazine]
  Scientific journal
• Effect of coagulant basicity on virus removal from water by polyferric chloride
  Nobutaka Shirasaki; Taku Matsushita; Yoshihiko Matsui; Takuya Marubayashi
  Journal of Water Supply: Research and Technology - AQUA, 65, 4, 322, 329, Jun. 2016, [Peer-reviewed], [International Magazine]
  Scientific journal
• Characterization of recombinant norovirus virus-like particles and evaluation of their applicability to the investigation of norovirus removal performance in membrane filtration processes
  N. Shirasaki; T. Matsushita; Y. Matsui; K. Ohno
  Water Science and Technology: Water Supply, 16, 3, 737, 745, Jun. 2016, [Peer-reviewed], [International Magazine]
  Scientific journal
• Use of orbitrap-MS/MS and QSAR analyses to estimate mutagenic transformation products of iopamidol generated during ozonation and chlorination
  Taku Matsushita; Masahiro Hashizuka; Taisuke Kuriyama; Yoshihiko Matsui; Nobutaka Shirasaki
  Chemosphere, 148, 233, 240, Apr. 2016, [Peer-reviewed], [International Magazine]
  Scientific journal
• Effect of aluminum hydrolyte species on human enterovirus removal from water during the coagulation process
  N. Shirasaki; T. Matsushita; Y. Matsui; T. Marubayashi
  Chemical Engineering Journal, 284, 786, 793, 2016, [Peer-reviewed], [International Magazine]
  Scientific journal
• Adsorption capacities of activated carbons for geosmin and 2-methylisoborneol vary with activated carbon particle size: Effects of adsorbent and adsorbate characteristics
  Yoshihiko Matsui; Soichi Nakao; Asuka Sakamoto; Takuma Taniguchi; Long Pan; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 85, 95, 102, 05 Nov. 2015, [Peer-reviewed], [International Magazine]
  Scientific journal
• Changes in mutagenicity and acute toxicity of solutions of iodinated X-ray contrast media during chlorination
  Taku Matsushita; Nozomi Kobayashi; Masahiro Hashizuka; Haruki Sakuma; Takashi Kondo; Yoshihiko Matsui; Nobutaka Shirasaki
  Chemosphere, 135, 101, 107, 01 Sep. 2015, [Peer-reviewed], [International Magazine]
  Scientific journal
• Hydraulically irreversible membrane fouling during coagulation-microfiltration and its control by using high-basicity polyaluminum chloride
  Masaoki Kimura; Yoshihiko Matsui; Shun Saito; Tomoya Takahashi; Midori Nakagawa; Nobutaka Shirasaki; Taku Matsushita
  Journal of Membrane Science, 477, 115, 122, 01 Mar. 2015, [Peer-reviewed], [International Magazine]
  Scientific journal
• Mechanisms of trichloramine removal with activated carbon: Stoichiometric analysis with isotopically labeled trichloramine and theoretical analysis with a diffusion-reaction model
  Miki Sakuma; Taku Matsushita; Yoshihiko Matsui; Tomoko Aki; Masahito Isaka; Nobutaka Shirasaki
  Water Research, 68, 839, 848, 01 Jan. 2015, [Peer-reviewed], [International Magazine]
  Scientific journal
• Removal of iodide from water by chlorination and subsequent adsorption on powdered activated carbon
  Mariya Ikari; Yoshihiko Matsui; Yuta Suzuki; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 68, 227, 237, 01 Jan. 2015, [Peer-reviewed], [International Magazine]
  Scientific journal
• Decomposition of 1,4-dioxane by vacuum ultraviolet irradiation: Study of economic feasibility and by-product formation
  T. Matsushita; S. Hirai; T. Ishikawa; Y. Matsui; N. Shirasaki
  Process Safety and Environmental Protection, 94, C, 528, 541, 2015, [Peer-reviewed], [International Magazine]
  Scientific journal
• Effect of growth phase of cyanobacterium on release of intracellular geosmin from cells during microfiltration process
  Taku Matsushita; Keisuke Nakamura; Yoshihiko Matsui; Nobutaka Shirasaki
  Membrane Water Treatment, 6, 3, 225, 235, 2015, [Peer-reviewed], [International Magazine]
  Scientific journal
• Isotope microscopy visualization of the adsorption profile of 2-methylisoborneol and geosmin in powdered activated carbon
  Yoshihiko Matsui; Asuka Sakamoto; Soichi Nakao; Takuma Taniguchi; Taku Matsushita; Nobutaka Shirasaki; Naoya Sakamoto; Hisayoshi Yurimoto
  Environmental Science and Technology, 48, 18, 10897, 10903, 16 Sep. 2014, [Peer-reviewed], [International Magazine]
  Scientific journal
• Selecting pesticides for inclusion in drinking water quality guidelines on the basis of detection probability and ranking
  Kentaro Narita; Yoshihiko Matsui; Kensuke Iwao; Motoyuki Kamata; Taku Matsushita; Nobutaka Shirasaki
  Environment International, 63, 114, 120, Feb. 2014, [Peer-reviewed], [International Magazine]
  Scientific journal
• Improved virus removal by high-basicity polyaluminum coagulants compared to commercially available aluminum-based coagulants
  N. Shirasaki; T. Matsushita; Y. Matsui; A. Oshiba; T. Marubayashi; S. Sato
  Water Research, 48, 1, 375, 386, 01 Jan. 2014, [Peer-reviewed], [International Magazine]
  Scientific journal
• Virus removal by an in-line coagulation-ceramic microfiltration process with high-basicity polyaluminum coagulation pretreatment
  N. Shirasaki; T. Matsushita; Y. Matsui; T. Urasaki; M. Kimura; K. Ohno
  Water Science and Technology: Water Supply, 14, 3, 429, 437, 2014, [Peer-reviewed], [International Magazine]
  Scientific journal
• Relative source allocation of TDI to drinking water for derivation of a criterion for chloroform: A Monte-Carlo and multi-exposure assessment
  Shun Niizuma; Yoshihiko Matsui; Koichi Ohno; Sadahiko Itoh; Taku Matsushita; Nobutaka Shirasaki
  Regulatory Toxicology and Pharmacology, 67, 1, 98, 107, Oct. 2013, [Peer-reviewed], [International Magazine]
  Scientific journal
• Investigating norovirus removal by microfiltration, ultrafiltration, and precoagulation-microfiltration processes using recombinant norovirus virus-like particles and real-time immuno-PCR
  Taku Matsushita; Nobutaka Shirasaki; Yuichi Tatsuki; Yoshihiko Matsui
  Water Research, 47, 15, 5819, 5827, 01 Oct. 2013, [Peer-reviewed], [International Magazine]
  Scientific journal
• Minimizing residual aluminum concentration in treated water by tailoring properties of polyaluminum coagulants
  Masaoki Kimura; Yoshihiko Matsui; Kenta Kondo; Tairyo B. Ishikawa; Taku Matsushita; Nobutaka Shirasaki
  Water Research, 47, 6, 2075, 2084, Apr. 2013, [Peer-reviewed], [International Magazine]
  Scientific journal
• Adsorptive virus removal with super-powdered activated carbon
  Taku Matsushita; Hideaki Suzuki; Nobutaka Shirasaki; Yoshihiko Matsui; Koichi Ohno
  Separation and Purification Technology, 107, 79, 84, 2013, [Peer-reviewed], [International Magazine]
  Scientific journal
• Aluminum concentrations of sand filter and polymeric membrane filtrates: A comparative study
  Yoshihiko Matsui; Tairyo B. Ishikawa; Masaoki Kimura; Kaori Machida; Nobutaka Shirasaki; Taku Matsushita
  Separation and Purification Technology, 119, 58, 65, 2013, [Peer-reviewed], [International Magazine]
  Scientific journal
• Development of Novel Aluminum-Based Coagulant for Effective Virus Removal
  SHIRASAKI Nobutaka; MATSUSHITA Taku; MATSUI Yoshihiko; OSHIBA Atsushi
  Journal of Japan Society of Civil Engineers, Ser. G (Environmental Research), 68, 7, III_41, III_50, Japan Society of Civil Engineers, 2012, [Peer-reviewed]
  Japanese, Scientific journal, A novel aluminum-based coagulant for effective virus removal was developed in the present study based on the investigation of roles of the basicity, sulfate ion and aluminum speciation in coagulation of virus. The coagulation process with the novel aluminum-based coagulant effectively removed viruses compared with other aluminum-based coagulants, and achieved apporimately 6-log removals not only in the weakly acidic and neutral pH conditions but also weakly alkaline pH conditions. In addition, Al₁₃ and Al₃₀ polymers were detecteded by electrospray ionization mass spectrometry and ²⁷Al-NMR spectrometry in the novel aluminum-based coagulant. Accordingly, Al₁₃ and Al₃₀ species are probably dominant species to control the virus removal performance, and that lead effective removals of viruses in the coagulation process with novel aluminum-based coagulant even in the weakly alkaline pH condition.
• Difference in behaviors of F-specific DNA and RNA bacteriophages during coagulation-rapid sand filtration and coagulation-microfiltration processes
  N. Shirasaki; T. Matsushita; Y. Matsui; T. Urasaki; K. Ohno
  Water Science and Technology: Water Supply, 12, 5, 666, 673, 2012, [Peer-reviewed], [International Magazine]
  Scientific journal
• Virus inactivation during coagulation with aluminum coagulants
  Taku Matsushita; Nobutaka Shirasaki; Yoshihiko Matsui; Koichi Ohno
  Chemosphere, 85, 4, 571, 576, Oct. 2011, [Peer-reviewed], [International Magazine]
  Scientific journal
• Estimation of norovirus removal performance in a coagulation-rapid sand filtration process by using recombinant norovirus VLPs
  N. Shirasaki; T. Matsushita; Y. Matsui; A. Oshiba; K. Ohno
  Water Research, 44, 5, 1307, 1316, Mar. 2010, [Peer-reviewed], [International Magazine]
  Scientific journal
• Evaluation of norovirus removal performance in a coagulation-ceramic microfiltration process by using recombinant norovirus virus-like particles
  N. Shirasaki; T. Matsushita; Y. Matsui; T. Urasaki; A. Oshiba; K. Ohno
  Water Science and Technology, 61, 8, 2027, 2034, 2010, [Peer-reviewed], [International Magazine]
  Scientific journal
• Feasibility of in-line coagulation as a pretreatment for ceramic microfiltration to remove viruses
  Nobutaka Shirasaki; Taku Matsushita; Yoshihiko Matsui; Makoto Kobuke; Koichi Ohno
  Journal of Water Supply: Research and Technology - AQUA, 59, 8, 501, 511, 2010, [Peer-reviewed], [International Magazine]
  Scientific journal
• Comparison of behaviors of two surrogates for pathogenic waterborne viruses, bacteriophages Qβ and MS2, during the aluminum coagulation process
  N. Shirasaki; T. Matsushita; Y. Matsui; T. Urasaki; K. Ohno
  Water Research, 43, 3, 605, 612, Feb. 2009, [Peer-reviewed], [International Magazine]
  Scientific journal
• Comparison of removal performance of two surrogates for pathogenic waterborne viruses, bacteriophage Qβ and MS2, in a coagulation-ceramic microfiltration system
  N. Shirasaki; T. Matsushita; Y. Matsui; M. Kobuke; K. Ohno
  Journal of Membrane Science, 326, 2, 564, 571, 20 Jan. 2009, [Peer-reviewed], [International Magazine]
  Scientific journal
• 遺伝子組換えノロウイルス外套タンパク粒子(rNV-VLPs)を用いたヒトノロウイルスの浄水処理性評価
  白崎 伸隆; 松下 拓
  環境工学研究論文集, 46, 415, 422, 2009, [Peer-reviewed]
  Scientific journal
• Effects of reversible and irreversible membrane fouling on virus removal by a coagulation-microfiltration system
  Nobutaka Shirasaki; Taku Matsushita; Yoshihiko Matsui; Koichi Ohno
  Journal of Water Supply: Research and Technology - AQUA, 57, 7, 501, 506, Nov. 2008, [Peer-reviewed], [International Magazine]
  Scientific journal
• Virus removal in a hybrid coagulation-microfiltration system - Investigating mechanisms of virus removal by a combination of PCR and PFU methods
  N. Shirasaki; T. Matsushita; Y. Matsui; K. Ohno; M. Kobuke
  Water Science and Technology: Water Supply, 7, 5-6, 1, 8, 2007, [Peer-reviewed], [International Magazine]
  Scientific journal
• Analysing mass balance of viruses in a coagulation - Ceramic microfiltration hybrid system by a combination of the polymerase chain reaction (PCR) method and the plaque forming units (PFU) method
  Taku Matsushita; Y. Matsui; N. Shirasaki
  Water Science and Technology, 53, 7, 199, 207, 2006, [Peer-reviewed], [International Magazine]
  Scientific journal
• Effect of membrane pore size, coagulation time, and coagulant dose on virus removal by a coagulation-ceramic microfiltration hybrid system
  Taku Matsushita; Y. Matsui; N. Shirasaki; Y. Kato
  Desalination, 178, 1-3 SPEC. ISS., 21, 26, 10 Jul. 2005, [Peer-reviewed], [International Magazine]
  Scientific journal

• 水理公式集例題集（2024年版）
  泉 典洋; 手計 太一; 赤松 良久; 入江 政安; 内田 龍彦; 小原 一哉; 片山 直哉; 佐山 敬洋; 白崎 伸隆; 山城 賢
  土木学会, Dec. 2024, [Joint work]
• 定量的微生物リスク評価－水安全管理への適用－（日本語版）
  島﨑 大; 原本 英司; 伊藤 禎彦; 真砂 佳史; 渡部 徹; 大野 浩一; 中久保 豊彦; 大河内 由美子; 春日 郁朗; 三浦 尚之; 橋本 温; 白崎 伸隆; 清 和成; 浅田 安廣; 佐野 大輔; 大瀧 雅寛
  国立保健医療科学院, Mar. 2020, [Joint work]

• 水・物質循環工学特論, 2024年, 修士課程, 工学院
• 水・物質循環工学特論, 2024年, 博士後期課程, 工学院
• 環境工学序論, 2024年, 学士課程, 工学部
• 環境工学, 2024年, 学士課程, 工学部
• 反応工学演習, 2024年, 学士課程, 工学部
• 流体工学Ⅱ, 2024年, 学士課程, 工学部
• 環境工学実験Ⅱ, 2024年, 学士課程, 工学部
• 工学基礎演習, 2024年, 学士課程, 工学部
• 環境工学概論, 2024年, 学士課程, 工学部
• 環境リスク解析学, 2024年, 学士課程, 工学部

• 国際水協会
• 日本水環境学会
• 土木学会
• ウイルス性下痢症研究会

• 革新的VLPsの創成が拓くウイルス浄水処理の新展開
  科学技術推進機構 創発的研究支援事業
  2022 - 2028
  白崎伸隆
  Principal investigator
• 培養からの脱却による培養困難なウイルスの浄水処理性評価法の創造
  日本学術振興会科学研究費補助金 基盤研究（A）
  2025 - 2027
  松下拓, 白崎伸隆
  Coinvestigator
• 単離培養技術とリバースジェネティクス法を併用した病原ウイルスの浄水消毒処理性評価
  日本学術振興会科学研究費補助金 基盤研究（B）
  2025 - 2027
  白崎伸隆, 松下拓
  Principal investigator
• ノロウイルスによる水系感染症を高度・高効率に制御可能な新規浄水処理システムの開発
  住友電工グループ社会貢献基金 2025年度学術・研究助成
  2025 - 2026
  白崎伸隆
• 水道原水河川に存在する病原ウイルスの感染力評価：活性炭と限外ろ過膜を組み合わせた新規ウイルス濃縮法の構築と適用
  河川財団 令和6年度河川基金助成 一般研究者
  2024 - 2025
  白崎伸隆
  Principal investigator
• 浄水消毒工程におけるヒトサポウイルスの未知動態の解明
  戸田育英財団 2025度研究助成金
  2025
  白崎伸隆
• ヒトiPS由来腸管上皮細胞を活用した浄水消毒工程におけるノロウイルスの未知動態の解明
  前田記念工学振興財団 令和7年度研究助成
  2025
  白崎伸隆
  Principal investigator
• 遺伝子組換と非ウイルスベクター技術を用いた培養に頼らないウイルスの浄水処理性評価
  日本学術振興会科学研究費補助金 基盤研究（A）
  2022 - 2024
  松下拓, 白崎伸隆
  Coinvestigator
• 単離技術と遺伝子操作系を駆使した遺伝的に多様な病原ウイルスの浄水消毒処理性評価
  日本学術振興会科学研究費補助金 基盤研究（B）
  2022 - 2024
  白崎伸隆, 松下拓
  Principal investigator
• サポウイルスに対する浄水消毒処理の有効性評価：In vitro細胞培養増殖系の活用
  前田記念工学振興財団 令和6年度研究助成
  2024
  白崎伸隆
  Principal investigator
• 汎用細胞増殖系を活用した浄水処理工程におけるサポウイルスの未知動態の解明
  日本学術振興会科学研究費補助金 挑戦的研究（萌芽）
  2022 - 2023
  白崎伸隆
  Principal investigator
• 超微粉炭プレコートと超高塩基度PACl凝集によるファウリングフリー膜ろ過
  日本学術振興会科学研究費補助金 基盤研究（A）
  2021 - 2023
  松井佳彦, 松下拓, 白崎伸隆, 安藤直哉
  Coinvestigator
• ICC-PCR法とPMAxx-PCR法を併用した水道原水における感染力を有する病原ウイルスの存在実態の把握
  前田記念工学振興財団 令和5年度研究助成
  2023
  白崎伸隆
  Principal investigator
• 感染力評価と外殻タンパク質損傷評価を併用した水道原水河川における病原ウイルスの存在実態の把握
  大林財団 2022年度研究助成
  2023
  白崎伸隆
  Principal investigator
• 急速砂ろ過方式から膜ろ過方式への浄水施設更新前後におけるウイルス除去性能の比較
  クボタ若手研究者研究奨励制度（水道分野） 第2回
  2021 - 2022
  白崎伸隆
  Principal investigator
• 浄水処理におけるヒト感染コロナウイルスの除去・不活化特性の評価
  フソウ技術開発振興基金 令和2年度研究助成
  2020 - 2021
  白崎伸隆
  Principal investigator
• リバースジェネティクス法を用いたウイルス野生株・流行株の塩素消毒不活化特性の把握
  日本学術振興会科学研究費補助金 挑戦的研究（萌芽）
  2020 - 2021
  白崎伸隆
  Principal investigator
• 遺伝的多様性を考慮した水道原水中に存在する病原ウイルスの浄水処理性評価
  日本学術振興会科学研究費補助金 基盤研究（B）
  2019 - 2021
  白崎伸隆, 松井佳彦, 松下拓
  Principal investigator
• 培養に頼らないウイルスの浄水処理性評価手法と高効率浄水ウイルス処理システムの構築
  日本学術振興会科学研究費補助金 基盤研究（A）
  2018 - 2021
  松下拓, 松井佳彦, 白崎伸隆
  Coinvestigator
• ヒト感染コロナウイルスの浄水処理性の評価：凝集ろ過分離性及び消毒不活化性の把握
  前田記念工学振興財団 令和3年度研究助成
  2021
  白崎伸隆
  Principal investigator
• 遺伝子封入VLPsを用いた培養困難なノロウイルスの浄水処理性評価
  フソウ技術開発振興基金 令和元年度研究助成
  2019 - 2020
  白崎伸隆
  Principal investigator
• 安全良質な水の持続的供給のための革新的前処理－膜分離浄水システム
  日本学術振興会科学研究費補助金 基盤研究（S）
  2016 - 2020
  松井佳彦, 松下拓, 白崎伸隆
  Coinvestigator
• 標識ラベルした凝集剤と同位体顕微鏡観察による膜ろ過ファウリングの解明
  日本学術振興会科学研究費補助金 挑戦的研究（萌芽）
  2018 - 2019
  松井佳彦, 白崎伸隆
  Coinvestigator
• 水道原水中に高濃度で存在するトウガラシ微斑ウイルスを指標とした実浄水処理場におけるウイルスの処理性評価
  フソウ技術開発振興基金 平成30年度研究助成
  2018 - 2019
  白崎伸隆
  Principal investigator
• DNAを封入したウイルス外套蛋白粒子を用いた培養困難なウイルスの浄水処理性評価
  日本学術振興会科学研究費補助金 挑戦的研究（萌芽）
  2017 - 2018
  松下拓, 白崎伸隆
  Coinvestigator
• 水道原水中に高濃度で存在するトウガラシ微斑ウイルスを用いた実浄水処理場における水系感染症ウイルスの処理性の推定
  平成29年度クリタ水･環境科学振興財団 国内研究助成 自然科学・技術（1）
  2017 - 2018
  白崎伸隆
  Principal investigator
• 遺伝子型の差異を考慮した培養不可能なウイルス及び消毒耐性ウイルスの浄水処理性評価
  日本学術振興会科学研究費補助金 若手研究（A）
  2016 - 2018
  白崎伸隆
  Principal investigator
• カプシドタンパクの精密質量分析によるウイルス消毒不活化・消毒耐性メカニズムの解明
  日本学術振興会科学研究費補助金 挑戦的萌芽研究
  2016 - 2017
  白崎伸隆
  Principal investigator
• 遺伝子封入VLPsを用いた培養困難なウイルスの浄水処理性評価
  ノースティック財団・若手研究人材育成事業 若手研究人材・ネットワーク育成補助金（ノースタレント補助金）
  2017
  白崎伸隆
  Principal investigator
• PMA-PCR法による水道原水河川における感染性を有する病原ウイルスの存在実態の把握
  河川財団 平成29年度河川基金助成 若手研究者 一般的助成
  2017
  白崎伸隆
  Principal investigator
• 水系感染症ウイルスを高度・高効率に処理可能な先端的ウイルス除去システムの開発
  向科学技術振興財団 平成28年度研究助成
  2017
  白崎伸隆
  Principal investigator
• ヒト嗅覚を検出器としたGC/MS法の確立とそれを用いた浄水異臭味の全体像の把握
  日本学術振興会科学研究費補助金 挑戦的萌芽研究
  2015 - 2016
  松下拓, 白崎伸隆
  Coinvestigator
• 分離膜のどこでファウリングが生じているのか：安定同位体顕微鏡による解明
  日本学術振興会科学研究費補助金 挑戦的萌芽研究
  2015 - 2016
  松井佳彦, 白崎伸隆
  Coinvestigator
• 先端的要素技術と膜分離の統合による水処理システムの革新
  日本学術振興会科学研究費補助金 基盤研究（S）
  2012 - 2016
  松井佳彦; 松下拓; 白崎伸隆
  Coinvestigator
• Contaminant Candidate Listに掲載された水系感染症ウイルスの浄水処理性評価及びウイルス処理性指標の探索
  平成26年度クリタ水･環境科学振興財団 国内研究助成 自然科学・技術（1）
  2014 - 2015
  白崎伸隆
  Principal investigator
• 精密質量分析を応用した新手法による水系感染症ウイルスの消毒不活化メカニズムの解明
  日本学術振興会科学研究費補助金 挑戦的萌芽研究
  2014 - 2015
  白崎伸隆
  Principal investigator
• 培養不可能な水系感染症ウイルスの浄水処理性評価とウイルス処理技術の高度・高効率化
  日本学術振興会科学研究費補助金 若手研究（A）
  2013 - 2015
  白崎伸隆
  Principal investigator
• 培養不可能な水系感染症ウイルスの新規浄水処理性評価手法の開発と応用
  住友財団 2012年度環境研究助成
  2012 - 2013
  白崎伸隆
  Principal investigator
• ウイルス様粒子と新規免疫PCR法を併用したノロウイルスの膜ろ過処理性評価
  服部報公会 平成24年度工学研究奨励援助金
  2012 - 2013
  白崎伸隆
  Principal investigator
• 蛍光偏光を用いた感染性を有する水系感染症ウイルスの迅速且つ簡便な新規定量法の開発
  日本学術振興会科学研究費補助金 挑戦的萌芽研究
  2012 - 2013
  白崎伸隆
  Principal investigator
• 機能性凝集剤による前凝集とセラミック膜ろ過を融合した先端的ウイルス処理システムの開発
  前田記念工学振興財団 平成25年度研究助成
  2013
  白崎伸隆
  Principal investigator
• ウイルス様粒子（VLPs）を用いた培養不可能な水系感染症ウイルスの浄水処理性評価
  平成23年度クリタ水･環境科学振興財団 国内研究助成 自然科学分野 萌芽的研究
  2011 - 2012
  白崎伸隆
  Principal investigator
• ウイルスを含む広範な原水水質に対応し得る新規凝集剤の開発
  国際科学技術財団 2012年研究助成
  2012
  白崎伸隆
  Principal investigator
• 吸着・凝集・膜分離を融合した次世代型ウイルス除去システムの開発
  JFE21世紀財団 2011年度技術研究助成 地球環境・地球温暖化防止技術研究
  2012
  白崎伸隆
  Principal investigator
• ウイルス処理に有効な新規凝集剤の開発
  日本学術振興会科学研究費補助金 研究活動スタート支援
  2011
  白崎伸隆
  Principal investigator
• ウイルス様粒子（VLPs）を用いたノロウイルスの浄水処理性の評価
  日本学術振興会科学研究費補助金 特別研究員奨励費
  2009 - 2010
  白崎伸隆
  水系感染症を引き起こす病原性ウイルスの中でも,感染事例が世界中で増加しているヒトノロウイルスは,未だ効率的な培養法が確立されていないことから,添加実験による浄水処理性の評価を行うために必要なウイルス量を確保することが極めて困難であり,培養可能な病原性ウイルスと比べて研究が格段に遅れている.そこで,本研究では,ヒトノロウイルスの物理的な浄水処理性を,遺伝子組換えバキュロウイルスとカイコを用いたタンパク質発現法により発現させたヒトノロウイルス外套タンパク粒子(VLPs)を用いて評価することを目的とした.
  本年度は,凝集沈澱-MF膜ろ過処理におけるVLPsの処理性を調べた.凝集沈澱-MF膜ろ過処理においては,凝集剤としてPACIを用いた場合,4log以上のVLPsの除去率が得られた.従って,凝集沈澱-MF膜ろ過処理を用いることにより,米国環境保護局の要求する4logの腸管系ウイルスの除去率を達成し得ることが示唆された.一方,凝集剤としてalumを用いた場合,VLPsの除去率は約3logとなり,PACIを用いた場合の除去率よりも低くなった.従って,凝集沈澱-MF膜ろ過処理においては,PACIを用いることにより,alumを用いる場合に比べて効果的にVLPsを除去できることが分かった.加えて,VLPsと大腸菌ファージQβおよびMS2の処理性を比較したところ,いずれの凝集剤を用いた場合でも,QβおよびMS2の除去率は,VLPsの除去率よりも低くなった.従って,凝集沈澱-MF膜ろ過処理においては,Qβ,MS2共にヒトノロウイルスの安全側の指標と成り得る可能性が示された.
  Principal investigator