研究者基本情報

• 博士（医学）, 北海道大学, 2021年09月
• 学士（医学）, 北海道大学, 2014年03月

• https://researchmap.jp/satonoritsuneta

• https://orcid.org/0000-0003-0739-1975
• https://jglobal.jst.go.jp/detail?JGLOBAL_ID=202101012489110760

• 80944868

• https://orcid.org/0000-0003-0739-1975

• 202101012489110760

• 心臓MRI
• 心臓CT
• 循環器画像診断
• 画像診断学

• ライフサイエンス, 放射線科学, 循環器画像診断学

• 学士課程, 歯学部
• 博士課程, 歯学院

研究活動情報

• 2023年11月, Hong Kong College of Radiologists, The Education and Research Fund of HKCR
  常田慧徳
• 2023年04月, 日本磁気共鳴医学会, ISMRM Travel Award
  常田慧徳
• 2019年07月, 日本心臓血管放射線研究会, 学術奨励賞
  常田慧徳

• Effects of partial splenic embolization and portosystemic shunt occlusion on portal venous hemodynamics using 4D flow MRI.
  Daisuke Kato; Naoya Kinota; Daisuke Abo; Satonori Tsuneta; Ryo Morita; Takaaki Fujii; Koji Yamasaki; Motoma Kanaya; Kinya Ishizaka; Takuya Sho; Tatsuhiko Kakisaka; Kohsuke Kudo
  Abdominal radiology (New York), 2026年05月06日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, PURPOSE: To quantitatively evaluate changes in portal venous hemodynamics after partial splenic embolization (PSE) and portosystemic shunt occlusion (PSO) using four-dimensional (4D) flow magnetic resonance imaging (MRI). METHODS: This retrospective cohort study included 30 procedures (16 PSE and 14 PSO) performed between 2019 and 2025. Flow rates were measured in the main portal vein (MPV), splenic vein (SpV), superior mesenteric vein (SMV), and portosystemic shunts (PSS) using pre- and post-procedural 4D flow MRI. For PSE, correlations were assessed between changes in MPV and SpV flow, and between vessel-specific flow change ratios and the embolic volume ratio. For PSO, changes in MPV flow were compared based on whether all PSS were treated, and correlation was assessed between flow changes in MPV and PSS flow. RESULTS: After PSE, MPV flow decreased (median, 751.0 to 441.5 mL/min; p = 0.025) as did SpV flow (482.5 to 323.0 mL/min; p = 0.001), whereas SMV flow remained unchanged. Changes in MPV and SpV flow were strongly correlated (ρ = 0.726, p = 0.002). The embolic volume ratio showed a moderate correlation with the SpV flow change ratio (ρ = 0.563, p = 0.036), but not with the MPV flow change ratio. After PSO, MPV flow increased (544.5 to 692.5 mL/min; p < 0.001), along with SpV flow (63.0 to 231.5 mL/min; p = 0.001), while SMV flow did not change significantly. The increase in MPV flow was greater when all PSS were treated than when they were not (140.0 vs. 17.0 mL/min; p = 0.019), and was not correlated with PSS flow. CONCLUSION: 4D flow MRI demonstrates that PSE decreases portal and splenic venous flow, whereas PSO increases both. These findings provide quantitative insight into complex treatment-related hemodynamic changes in the portal venous system.
• Effects of gadolinium-based contrast agents on the cardiac diffusion-weighted images of phantoms and patients.
  Satonori Tsuneta; Satoru Aono; Jihun Kwon; Masami Yoneyama; Hiroki Uehara; Takuya Aoike; Sakae Takenaka; Hidenori Koyano; Noriyuki Fujima; Toshiyuki Nagai; Toshihisa Anzai; Kazuyuki Minowa; Kohsuke Kudo
  Magma (New York, N.Y.), 2026年04月10日, ［査読有り］, ［筆頭著者, 責任著者］, ［国際誌］
  英語, 研究論文（学術雑誌）, OBJECTIVES: To investigate the effects of gadolinium-based contrast agent (GBCA) on cardiac diffusion-weighted imaging (cDWI) and cDWI feasibility during the interval between GBCA administration and late gadolinium enhancement (LGE) imaging to streamline workflow. MATERIALS AND METHODS: Phantoms containing varying GBCA concentration (0-1.0 mM/L) were scanned with stimulated echo acquisition mode-based cDWI (STEAM-cDWI) with various heart rates (HRs) (30-200 beats/min) and second-order motion-compensated spin-echo-based cDWI (M2SE-cDWI) with various echo times (TEs) (75-500 ms). For patient study, 9 patients underwent STEAM-cDWI and 13 underwent M2SE-cDWI before and after GBCA administration. Contrast ratio (CR) and contrast-to-noise ratio (CNR) between the left ventricular myocardium and cavity, and ADC values were assessed. RESULTS: In phantoms, higher GBCA concentration, lower HR, and prolonged TE reduced SI. In STEAM-cDWI, CR and CNR significantly reduced after GBCA administration (CR of b = 400, 2.29 [1.80-5.46] vs. 1.15 [0.78-1.29], p = 0.0004; CNR of b = 400, 7.58 [4.82-11.1] vs. 0.57 [- 1.34 to 1.35], p = 0.0006; respectively); ADC values remained unchanged. In M2SE-cDWI, ADC values significantly decreased after GBCA administration (1.62 [1.15-1.97] vs. 1.26 [1.12- 1.51], × 10-3 mm2/s respectively, p = 0.004); only CR at b = 400 decreased significantly. DISCUSSION: cDWI is not recommended during the interval between GBCA administration and LGE imaging.
• Multimodality imaging of the right ventricular outflow tract haemangioma requiring pulmonary valve replacement.
  Rui Katano; Satonori Tsuneta; Satoru Wakasa; Atsushi Tada
  European heart journal. Case reports, 10, 3, ytag123, 2026年03月, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）
• Worldwide Radiation Dose in Coronary Artery Disease Diagnostic Imaging.
  Andrew J Einstein; Michelle C Williams; Jonathan R Weir-McCall; Leslee J Shaw; Ganesan Karthikeyan; Nathan Better; João V Vitola; Rodrigo J Cerci; Sharmila Dorbala; Salah E Bouyoucef; Andrew D Choi; Gianluca Pontone; Elgin Ozkan; Lee D Yang; Luca Bremner; Michelle Castillo; Yosef A Cohen; Eli Malkovskiy; Ismaila Ayoola; Anna Veduta; Danylo Yurystovskyi; Yaroslav Pynda; Thomas N B Pascual; Peter Knoll; Maurizio Dondi; Diana Paez
  JAMA, 2026年02月25日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, IMPORTANCE: In recent decades, there has been marked worldwide growth in diagnostic testing for coronary artery disease (CAD), with several common imaging modalities exposing patients to ionizing radiation. OBJECTIVE: To examine worldwide radiation doses for patients undergoing noninvasive CAD diagnostic testing. DESIGN, SETTING, AND PARTICIPANTS: This worldwide, cross-sectional study was conducted of radiation dose from noninvasive CAD imaging in 2023, using a consecutive sample of all 19 302 adults undergoing noninvasive CAD diagnostic testing at 742 centers in 101 countries during a single week in October to December 2023. EXPOSURES: Participants underwent CAD testing with single-photon emission computed tomography (SPECT) or positron emission tomography (PET) nuclear cardiac imaging, cardiac computed tomography for coronary artery calcium scoring (CACS), or coronary computed tomography angiograph (CCTA). MAIN OUTCOMES AND MEASURES: The primary outcomes were radiation effective dose to patients and the percentage of centers with median effective dose less than or equal to 9 mSv, as recommended in guidelines. RESULTS: Of 19 302 patients, 8515 (44%) were females and the median (IQR) age was 63 (54-71) years. Effective dose varied considerably across diagnostic modalities, with median (IQR) effective dose of 1.2 (0.7-2.2) mSv for CACS, 2.0 (1.6-2.4) mSv for PET, 6.5 (3.9-8.6) mSv for SPECT, and 7.4 (3.5-15.5) mSv for CCTA. Significantly more centers performing nuclear cardiology than CCTA (81% vs 56%; P < .001) and patients undergoing nuclear cardiology studies than CCTA (79% vs 56%; P < .001) achieved median dose of less than or equal to 9 mSv. Doses for the same procedure differed significantly between world regions, being lowest in Western Europe (median [IQR], 4.8 [2.3-7.3] mSv for nuclear cardiology and 4.6 [2.4-9.8] mSv for CCTA) and highest in Latin America for nuclear cardiology (median [IQR], 7.8 [5.3-9.7] mSv) and Africa (median [IQR], 25.2 [14.7-35.3] mSv) for CCTA (P < .001 for all). In regression modeling, there was an inverse relationship between country income level and dose. Patient dose was 20% (95% CI, 3.6%-38.4%) higher in low- and middle-income countries than in high-income countries for nuclear cardiology, and as much as 96% (95% CI, 41.7%-170.8%) higher in low- and lower-middle-income countries than in high-income countries for CCTA (P < .001). Marked variation was observed within income levels and world regions. CONCLUSIONS AND RELEVANCE: Given increasing rates of CAD worldwide, these findings of marked variation in radiation dose to patients from diagnostic testing identify a critical need for training, standardized protocols, and updated equipment to reduce radiation worldwide. This especially affects patients in low- and middle-income countries and patients undergoing CCTA. There are therefore important opportunities to improve the quality of CAD diagnosis for patients across the globe.
• Prognostic value of preprocedural pulmonary artery to ascending aorta ratio on non-contrast computed tomography in patients undergoing mitral transcatheter edge-to-edge repair.
  Hiroki Uehara; Toshiyuki Nagai; So Sasaki; Kento Tamano; Toshifumi Tamura; Akinori Takahashi; Takeshi Hamaya; Yuki Mori; Yutaro Yasui; Sakae Takenaka; Satonori Tsuneta; Suguru Ishizaka; Yuta Kobayashi; Atsushi Tada; Taro Temma; Kiwamu Kamiya; Toshihisa Anzai
  Heart and vessels, 2026年01月21日, ［査読有り］, ［国内誌］
  英語, 研究論文（学術雑誌）
• Prognostic value of 18F-fluorodeoxyglucose positron emission tomography one month after initiation of prednisolone therapy in patients with cardiac sarcoidosis.
  Toshifumi Tamura; Sakae Takenaka; Toshiyuki Nagai; Satonori Tsuneta; Takeshi Hamaya; Kenji Hirata; Yoshiya Kato; Hirokazu Komoriyama; Yuta Kobayashi; Atsushi Tada; Sho Kazui; Yutaro Yasui; Akinori Takahashi; Kiwamu Kamiya; Taro Temma; Takahiro Sato; Ichizo Tsujino; Kohsuke Kudo; Satoshi Konno; Toshihisa Anzai
  International journal of cardiology, 448, 134181, 134181, 2026年01月15日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Current guidelines for cardiac sarcoidosis (CS) recommend maintaining the initial maximal dose of prednisolone (PSL) for one month after initiation; however, the prognostic significance of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) performed at this time point remains unclear. We sought to investigate whether FDG-PET performed at one month after the initiation of PSL is associated with adverse events in patients with CS. METHODS: We examined 109 consecutive CS patients who underwent FDG-PET at diagnosis and one month after initiating PSL between January 2010 and January 2025 in a university hospital. The change in maximum standardized uptake value (SUVmax) from baseline to one month was calculated. Responder was defined as those with an SUVmax reduction ≥25%, while non-responder had a reduction <25% or any increase. The primary outcome was a composite of aborted sudden cardiac death, sustained ventricular tachycardia, hospitalization of worsening heart failure, and all-cause death. RESULTS: Of the 109 patients, 83 were classified as responder and 26 as non-responder. Over a median follow-up of 4.9 years (interquartile range, 2.3-8.2), the primary outcome occurred in 37 patients. Non-responder had a significantly higher risk of the primary outcome, and this association persisted after sequential adjustment for established prognostic covariates. CONCLUSIONS: An inadequate reduction in SUVmax on FDG-PET performed one month after PSL initiation was independently associated with adverse clinical events in patients with CS. These findings suggest that non-responder represents a clinical challenge and even very early follow-up FDG-PET may provide prognostic insights.
• Comparative evaluation of four reconstruction techniques for prostate T2-weighted MRI: Sensitivity encoding, compressed sensing, deep learning, and super-resolution.
  Noriko Nishioka; Noriyuki Fujima; Satonori Tsuneta; Daisuke Kato; Takashi Kamiishi; Masato Yoshikawa; Rina Kimura; Keita Sakamoto; Ryuji Matsumoto; Takashige Abe; Jihun Kwon; Masami Yoneyama; Kohsuke Kudo
  European journal of radiology open, 15, 100671, 100671, 2025年12月, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, PURPOSE: To evaluate and compare the image quality and lesion conspicuity of prostate T2-weighted imaging (T2WI) using four reconstruction methods: conventional Sensitivity Encoding (SENSE), compressed sensing (CS), model-based deep learning reconstruction (DL), and deep learning super-resolution reconstruction (SR). METHODS: This retrospective study included 49 patients who underwent multiparametric MRI (mpMRI) or biparametric MRI (bpMRI) for suspected prostate cancer. Axial T2WI was acquired using two protocols: conventional SENSE and CS-based acquisition. From the CS-based data, three reconstruction methods (CS, DL, and SR) were applied to generate additional images. Two board-certified radiologists independently assessed overall image quality and sharpness using a 4-point Likert scale (1 = poor, 4 = excellent). Quantitative analysis included signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and sharpness index. PI-RADS T2WI scoring and lesion conspicuity were preliminarily evaluated in 18 individuals with pathologically confirmed prostate cancer. Statistical comparisons were conducted using the Wilcoxon signed-rank test. RESULTS: SR consistently achieved the highest scores in both qualitative (overall image quality, image sharpness) and quantitative (SNR, CNR, sharpness index) assessments, compared with SENSE, CS, and DL (all pairwise comparisons, Bonferroni-corrected p < 0.0001). In lesion-based analysis, SR showed a trend toward improved lesion conspicuity, although PI-RADS T2WI scores were similar across reconstruction. CONCLUSION: SR reconstruction demonstrated superior image quality in both qualitative and quantitative assessments and showed potential benefits for lesion visualization. These findings, although based on a small sample, suggest that SR may be a promising approach for prostate MRI and warrants further investigation in larger populations.
• Role of Passive Leg Raise Stress Echocardiography in Latent Stiff Left Atrial Syndrome
  Michito Murayama; Hiroyuki Iwano; Satonori Tsuneta; Noriyuki Otsuka; Makoto Kambayashi; Yui Shimono; Yoji Tamaki; Suguru Ishizaka; Shinobu Yokoyama; Hisao Nishino; Sanae Kaga; Toshiyuki Nagai; Toshihisa Anzai
  Circulation: Cardiovascular Imaging, 2025年12月, ［査読有り］
  研究論文（学術雑誌）
• Impact of breast tumor size discrepancy between contrast-enhanced and conventional ultrasonography on axillary node metastasis: a retrospective cohort study.
  Tomohiro Oshino; Hirokazu Shimizu; Megumi Sato; Mutsumi Nishida; Tatsunori Horie; Satonori Tsuneta; Fumi Kato; Mitsuchika Hosoda; Isao Yokota; Kohsuke Kudo; Masato Takahashi
  BMC cancer, 25, 1, 1718, 1718, 2025年11月05日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Conventional ultrasonography (cUS) and contrast-enhanced ultrasonography (CEUS) are used to evaluate breast cancer tumors and axillary lymph nodes (ALN), by which the treatment strategy for breast cancer is determined. A breast tumor size discrepancy on CEUS compared with cUS is often observed, for which the reasons are unclear. We hypothesized that this discrepancy reflects the metastatic potential, and this study investigated the association between size discrepancies on cUS and CEUS in relation to ALN metastasis in breast cancer. METHODS: This retrospective study enrolled 259 patients who underwent surgery for breast cancer after preoperative cUS and CEUS examinations. Patients were grouped into a DISCR (i.e., tumor size discrepancy ≥ 4.0 mm between CEUS and cUS measurements) and non-DISCR group. The primary outcome was ALN metastasis, defined by pathological evaluation. Secondary outcomes were the 5-year recurrence-free survival rates. RESULTS: There were 94 patients in the DISCR and 165 in the non-DISCR groups. No tumor size differences measured by cUS were observed between two groups (p = 0.82), whereas the DISCR group had a significantly higher rate of ALN metastasis (p < 0.01). Multivariate analyses showed a discrepancy of ≥ 4.0 mm was a risk for ALN metastasis (odds ratio: 5.838, 95% confidence interval [CI]: 2.408-14.155). The 5-year recurrence-free survival rate was lower in the DISCR (0.750, 95% CI: 0.632-0.868) than in the non-DISCR (0.924, 95% CI; 0.870-0.978) group. CONCLUSION: An increase in contrast-enhanced ultrasonography tumor size is helpful for assessing axillary lymph node metastasis and prognosis.
• Blood Flow Dynamics of Self-Expanding versus Balloon-Expandable Transcatheter Aortic Valve Replacement in Patients with a Small Aortic Annulus.
  Takeshi Hamaya; Kiwamu Kamiya; Toshiyuki Nagai; Satonori Tsuneta; Noriko Oyama-Manabe; Hirokazu Komoriyama; Yuki Takahashi; Akinori Takahashi; Yuki Mori; Yoshifumi Mizuguchi; Sakae Takenaka; Suguru Ishizaka; Takuma Sato; Taro Temma; Yasushige Shingu; Kohsuke Kudo; Satoru Wakasa; Toshihisa Anzai
  The Canadian journal of cardiology, 2025年10月07日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: A recent trial showed the supra-annular self-expanding valve (SEV) provides superior valve function compared to the balloon-expandable valve (BEV) in patients with aortic stenosis (AS) and a small aortic annulus (SAA) undergoing transcatheter aortic valve replacement (TAVR). This study aimed to compare blood flow hemodynamics between SEV and BEV using four-dimensional flow cardiovascular magnetic resonance imaging (4D flow CMR). METHODS: We prospectively examined 166 consecutive patients with AS who underwent TAVR between May 2018 and March 2025. SAA was defined as an annular area ≤ 430 mm2. Patients were categorized into four groups: SAA-SEV (n = 35), SAA-BEV (n = 66), non-SAA-SEV (n = 21), and non-SAA-BEV (n = 44). Blood flow patterns, wall shear stress (WSS), and energy loss were assessed using 4D flow CMR. RESULTS: In patients with SAA, the SEV group showed significantly greater absolute reductions in vortical flow, helical flow, and flow eccentricity after TAVR compared to the BEV group (-0.47 ± 0.9 vs. 0.15 ± 1.0, P = 0.003; -0.79 ± 0.8 vs. -0.36 ± 0.9, P = 0.008; and -0.59 ± 0.9 vs. -0.20 ± 0.8, P = 0.024, respectively). The absolute reduction of average WSS was also significantly greater in the SEV group (-2.0 [-3.0 to -0.9] Pa vs. -0.9 [-2.5 to 0.4] Pa, P = 0.037). These differences were not observed in the non-SAA groups. CONCLUSIONS: In SAA patients undergoing TAVR, SEV demonstrated a significantly greater reduction in abnormal blood flow patterns and average WSS than BEV.
• Multi-centre Investigation of Cardiac Diffusion Tensor Imaging in Healthy Volunteers by SCMR Cardiac Diffusion Special Interest Group NETwork (SIGNET).
  Irvin Teh; Kévin Moulin; Pedro F Ferreira; Julie Absil; Maryam Afzali; Peter Agger; Behnaz Akbari; Anthony H Aletras; Satoru Aono; Charles Benton; Suryava Bhattacharya; Pierre Croisille; Yves De Bruecker; Erica Dall'Armellina; Daniel B Ennis; Carl Glessgen; Anna Glinska; Sandra Haltmeier; Ariel Hannum; Erik Hedström; Tawfik Hussein; Sarah Jones; George Joy; Karen Kettless; Won Yong Kim; Sebastian Kozerke; Julie Magat; Raja Muthupillai; Reza Nezafat; Sonia Nielles-Vallespin; John Oshinski; Valéry Ozenne; Dudley J Pennell; Roderick Pettigrew; Iain Pierce; Betty Raman; Agnieszka Sabisz; Jürgen E Schneider; Janet H Sherman; Abhishek Shetye; Rolf Symons; Philippe Thoma; Thomas Treibel; Satonori Tsuneta; Jean-Paul Vallee; Niels Vejlstrup; Magalie Viallon; Christopher Nguyen; Andrew D Scott; Christian T Stoeck
  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 101948, 101948, 2025年08月25日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Cardiac diffusion tensor imaging (cDTI) is an emerging technique for microstructural characterization of the heart and has shown clinical potential in a range of cardiomyopathies. However, there is substantial variation reported for in vivo cDTI results across the literature, and sensitivity of cDTI to differences in imaging sites, scanners, acquisition protocols and post-processing methods remains incompletely understood. METHODS: SIGNET is a prospective multi-centre, observational study in travelling and non-travelling healthy volunteers. The study was initiated by the executive board of the SCMR Cardiac Diffusion Special Interest Group (SIG) as a follow up to a previous multi-centre study on phantom validation of cardiac DTI and a recently published SCMR consensus statement on cardiac diffusion MRI. The study has been developed by the Project Management Committee in consultation with the SCMR Cardiac Diffusion SIG, which includes international experts in cardiac diffusion MRI. To date, more than 20 international institutions have engaged with the study, including sites that are new to cardiac DTI, making this the largest collaborative effort in the field. DISCUSSION: SIGNET will provide important information about the key sources of variation in cardiac DTI. This will help rationalise strategies for addressing and minimising such variation. Harmonisation of protocols in this and future studies will underpin efforts to translate cardiac DTI for clinical application.
• Right Ventricular Dysfunction in Lung Disease/Hypoxia-Associated Pulmonary Hypertension.
  Hideki Shima; Ichizo Tsujino; Toshitaka Nakaya; Junichi Nakamura; Ayako Igarashi-Sugimoto; Takahiro Sato; Taku Watanabe; Hiroshi Ohira; Ryo Hisada; Masaru Kato; Satonori Tsuneta; Isao Yokota; Satoshi Konno
  Journal of the American Heart Association, 14, 16, e042186, 2025年08月19日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Limited data exist on right ventricular (RV) function in lung disease/hypoxia-associated pulmonary hypertension (PH). We aimed to clarify the presence, characteristics, and clinical significance of RV dysfunction in patients with lung disease/hypoxia-associated PH. METHODS: We analyzed data from 3 groups of patients: those with lung disease/hypoxia-associated PH, those without PH, and those with pulmonary arterial hypertension (PAH). RV volume was assessed using cardiac magnetic resonance imaging, and RV pressure data were obtained by right heart catheterization and analyzed using dedicated software and a single-beat method. We then evaluated RV contractility by end-systolic elastance (Ees), diastolic function by β and end-diastolic elastance, and RV-pulmonary artery coupling by Ees/arterial elastance. RESULTS: We studied 68 patients with lung disease/hypoxia-associated PH, 40 without PH, and 93 with PAH. In the lung disease/hypoxia-associated PH group, Ees was sustained (0.46 [95% CI, 0.26-0.75] mm Hg/mL), whereas β (0.035 [95% CI, 0.022-0.049]) and end-diastolic elastance (0.19 [95% CI, 0.11-0.38] mm Hg/mL) were higher, and Ees/arterial elastance was lower (0.59 [95% CI, 0.27-0.79]) compared with the no-PH group. There were no differences in these values between the groups with lung disease/hypoxia-associated PH and PAH. Ees/arterial elastance was significantly correlated with the 6-minute walk distance and associated with mortality (hazard ratio, 0.18 [95% CI, 0.04-0.79]) in the group with PAH, but it was not in the group with lung disease/hypoxia-associated PH. Similarly, whereas the group with PAH showed improvement in β and Ees/arterial elastance with pulmonary vasodilator therapy, such improvement was not observed in the group with lung disease/hypoxia-associated PH. CONCLUSIONS: In lung disease/hypoxia-associated PH, RV contractility is preserved, whereas diastolic function and RV-pulmonary artery coupling are impaired. Further investigation is needed to elucidate the distinct clinical relevance of RV dysfunction in lung disease/hypoxia-associated PH.
• Evaluation of artificial-intelligence-based liver segmentation and its application for longitudinal liver volume measurement.
  Rina Kimura; Kenji Hirata; Satonori Tsuneta; Junki Takenaka; Shiro Watanabe; Daisuke Abo; Kohsuke Kudo
  Abdominal radiology (New York), 2025年06月10日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Accurate liver-volume measurements from CT scans are essential for treatment planning, particularly in liver resection cases, to avoid postoperative liver failure. However, manual segmentation is time-consuming and prone to variability. Advancements in artificial intelligence (AI), specifically convolutional neural networks, have enhanced liver segmentation accuracy. We aimed to identify optimal CT phases for AI-based liver volume estimation and apply the model to track liver volume changes over time. We also evaluated temporal changes in liver volume in participants without liver disease. METHODS: In this retrospective, single-center study, we assessed the performance of an open-source AI-based liver segmentation model previously reported, using non-contrast and dynamic CT phases. The accuracy of the model was compared with that of expert radiologists. The Dice similarity coefficient (DSC) was calculated across various CT phases, including arterial, portal venous, and non-contrast, to validate the model. The model was then applied to a longitudinal study involving 39 patients without liver disease (527 CT scans) to examine age-related liver volume changes over 5 to 20 years. RESULTS: The model demonstrated high accuracy across all phases compared to manual segmentation. Among the CT phases, the highest DSC of 0.988 ± 0.010 was in the arterial phase. The intraclass correlation coefficients for liver volume were also high, exceeding 0.9 for contrast-enhanced phases and 0.8 for non-contrast CT. In the longitudinal study, the model indicated an annual decrease of 0.95%. CONCLUSION: This model provides high accuracy in liver segmentation across various CT phases and offers insights into age-related liver volume reduction. Measuring changes in liver volume may help with the early detection of diseases and the understanding of pathophysiology.
• The Impact of Model-based Deep-learning Reconstruction Compared with that of Compressed Sensing-Sensitivity Encoding on the Image Quality and Precision of Cine Cardiac MR in Evaluating Left-ventricular Volume and Strain: A Study on Healthy Volunteers.
  Satonori Tsuneta; Satoru Aono; Rina Kimura; Jihun Kwon; Noriyuki Fujima; Kinya Ishizaka; Noriko Nishioka; Masami Yoneyama; Fumi Kato; Kazuyuki Minowa; Kohsuke Kudo
  Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2025年05月30日, ［査読有り］, ［筆頭著者, 責任著者］, ［国内誌］
  英語, 研究論文（学術雑誌）, PURPOSE: To evaluate the effect of model-based deep-learning reconstruction (DLR) compared with that of compressed sensing-sensitivity encoding (CS) on cine cardiac magnetic resonance (CMR). METHODS: Cine CMR images of 10 healthy volunteers were obtained with reduction factors of 2, 4, 6, and 8 and reconstructed using CS and DLR. The visual image quality scores assessed sharpness, image noise, and artifacts. Left-ventricular (LV) end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were manually measured. LV global circumferential strain (GCS) was automatically measured using the software. The precision of EDV, ESV, SV, EF, and GCS measurements was compared between CS and DLR using Bland-Altman analysis with full-sampling data as the gold standard. RESULTS: Compared with CS, DLR significantly improved image quality with reduction factors of 6 and 8. The precision of EDV and ESV with a reduction factor of 8, and GCS with reduction factors of 6 and 8 measurements improved with DLR compared with CS, whereas those of SV and EF measurements were not different between DLR and CS. CONCLUSION: The effect of DLR on cine CMR's image quality and precision in evaluating quantitative volume and strain was equal or superior to that of CS. DLR may replace CS for cine CMR.
• Reduced hemoglobin-corrected diffusing capacity in pulmonary arterial hypertension with preserved pulmonary function and morphology.
  Ayako Igarashi-Sugimoto; Ichizo Tsujino; Hideki Shima; Junichi Nakamura; Toshitaka Nakaya; Takahiro Sato; Taku Watanabe; Hiroshi Ohira; Kaoruko Shimizu; Takashi Yokota; Sari Iwasaki; Satonori Tsuneta; Isao Yokota; Satoshi Konno
  Respiratory investigation, 63, 4, 600, 607, 2025年05月08日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: The diffusing capacity and the transfer coefficient of the lung for carbon monoxide (DLCO and KCO, respectively) are reduced in pulmonary arterial hypertension; however, the effect of pulmonary arterial hypertension alone on these parameters and their clinical impact remain unclear. We aimed to elucidate the exclusive impact of pulmonary arterial hypertension on these two parameters and examine their association with other parameters. METHODS: We retrospectively selected patients with pulmonary arterial hypertension with normal pulmonary function upon pulmonary function testing and with normal lung parenchyma upon chest computed tomography. We calculated the hemoglobin-corrected DLCO (DLCO-Hbc) and KCO (KCO-Hbc) and examined their association with established pulmonary hypertension-related parameters. An exploratory analysis of pulmonary vasculopathy was performed in an autopsy case. RESULTS: We included 50 patients with pulmonary arterial hypertension for analysis. Their median %DLCO-Hbc and %KCO-Hbc were 62 % and 70 %, respectively. The DLCO-Hbc was associated with functional class, 6-min walk distance, alveolar-arterial oxygen tension difference, cardiac output, and pulmonary arterial hypertension-related death. The DLCO-Hbc and KCO-Hbc were also correlated with the lowest minute ventilation/carbon dioxide production ratio (ρ = -0.84 and -0.49, respectively), an index that represents ventilation-perfusion mismatch. The autopsy revealed pulmonary arterial hypertension-specific arteriopathy that was heterogeneously distributed in the lungs. CONCLUSIONS: The DLCO-Hbc and KCO-Hbc were reduced to 60 %-70 % in patients with pulmonary arterial hypertension even when their pulmonary function and morphology were preserved. The decreases were associated with pulmonary hypertension-related clinical parameters and survival and may be caused by heterogeneous vasculopathy and subsequent ventilation-perfusion mismatch.
• Serum Vasoactive Intestinal Peptide as a Novel Biomarker for Low-Voltage Areas in Patients With Atrial Fibrillation.
  Kotaro Nishino; Taro Temma; Hiroyuki Natsui; Masaya Watanabe; Motoki Nakao; Masahiro Kawasaki; Kintaro Shimano; Kei Kawakami; Shota Saito; Jiro Koya; Daishiro Tatsuta; Takuya Koizumi; Takahide Kadosaka; Taro Koya; Satonori Tsuneta; Kiwamu Kamiya; Toshiyuki Nagai; Toshihisa Anzai
  Journal of the American Heart Association, 14, 7, e039192, 2025年04月, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Low-voltage areas in the left atrium predict atrial fibrillation recurrence after catheter ablation and are associated with adverse outcomes like death, heart failure, and stroke. Detecting low-voltage areas (LVAs) typically requires invasive procedures, highlighting the need for a simple, minimally invasive marker. Vasoactive intestinal peptide (VIP), a neuropeptide released during parasympathetic stimulation, affects electrophysiological remodeling in atrial fibrillation. We hypothesized that serum VIP could serve as a biomarker for detecting LVAs in these patients. METHODS AND RESULTS: This prospective, cross-sectional study was conducted at Hokkaido University Hospital between August 2021 and September 2023. We included 108 patients with atrial fibrillation scheduled for catheter ablation. Blood samples were collected during ablation to measure VIP using an ELISA. Electroanatomical mapping identified LVAs, defined as regions with bipolar voltage ≤0.5 mV and occupying >5% of the left atrial surface. Statistical analyses evaluated the relationship between VIP and LVAs. Fifty-one patients (47%) had LVAs, with significantly higher serum VIP levels than those without (335.1 versus 247.7 pg/mL, P<0.001). VIP levels and female sex were statistically significant factors of LVAs. Adding VIP to the existing score significantly improved its discrimination (area under the curve: 0.784 versus 0.707, P<0.001). CONCLUSIONS: Serum VIP levels are higher in patients with atrial fibrillation with LVAs, suggesting its potential as a noninvasive biomarker for detecting these areas and improving clinical management.
• Prevalence, incidence, and clinical features of cardiac involvement in patients with pulmonary sarcoidosis
  Junichi Nakamura; Takahiro Sato; Hiroshi Ohira; Shuhei Yoshikawa; Takeshi Hattori; Osamu Manabe; Noriko Oyama-Manabe; Satonori Tsuneta; Hirokazu Kimura; Sakae Takenaka; Toshiyuki Nagai; Toshihisa Anzai; Masaharu Nishimura; Isao Yokota; Ichizo Tsujino; Satoshi Konnno
  Respiratory Medicine, 2025年03月, ［査読有り］
  研究論文（学術雑誌）
• Cardiac sarcoidosis with multiple intracardiac masses diagnosed by rectus femoris biopsy.
  Toshifumi Tamura; Satonori Tsuneta; Toshiyuki Nagai
  European heart journal, 2024年12月04日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）
• Enhancing the image quality of prostate diffusion-weighted imaging in patients with prostate cancer through model-based deep learning reconstruction.
  Noriko Nishioka; Noriyuki Fujima; Satonori Tsuneta; Masato Yoshikawa; Rina Kimura; Keita Sakamoto; Fumi Kato; Haruka Miyata; Hiroshi Kikuchi; Ryuji Matsumoto; Takashige Abe; Jihun Kwon; Masami Yoneyama; Kohsuke Kudo
  European journal of radiology open, 13, 100588, 100588, 2024年12月, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, PURPOSE: To evaluate the utility of model-based deep learning reconstruction in prostate diffusion-weighted imaging (DWI). METHODS: This retrospective study evaluated two prostate diffusion-weighted imaging (DWI) methods: deep learning reconstruction (DL-DWI) and traditional parallel imaging (PI-DWI). We examined 32 patients with radiologically diagnosed and histologically confirmed prostate cancer (PCa) lesions ≥10 mm. Image quality was evaluated both qualitatively (for overall quality, prostate conspicuity, and lesion conspicuity) and quantitatively, using the signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and apparent diffusion coefficient (ADC) for prostate tissue. RESULTS: In the qualitative evaluation, DL-DWI scored significantly higher than PI-DWI for all three parameters (p<0.0001). In the quantitative analysis, DL-DWI showed significantly higher SNR and CNR values compared to PI-DWI (p<0.0001). Both the prostate tissue and the lesions exhibited significantly higher ADC values in DL-DWI compared to PI-DWI (p<0.0001, p=0.0014, respectively). CONCLUSION: Model-based DL reconstruction enhanced both qualitative and quantitative aspects of image quality in prostate DWI. However, this study did not include comparisons with other DL-based methods, which is a limitation that warrants future research.
• Multimodal Assessment of Immunosuppressive Therapy in a Patient With Chronic Active Myocarditis 3 Months Following COVID-19 Infection.
  Yuta Kobayashi; Takeshi Hamaya; Toshiyuki Nagai; Yuki Mori; Takuma Sato; Satonori Tsuneta; Kento Wakabayashi; Kohsuke Kudo; Yoshihiro Matsuno; Toshihisa Anzai
  CJC open, 6, 6, 826, 829, 2024年06月, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）
• Chronic Active Myocarditis After Transapical Transcatheter Aortic Valve Implantation.
  Yuta Kobayashi; Toshiyuki Nagai; Kiwamu Kamiya; Satonori Tsuneta; Yasushige Shingu; Kento Wakabayashi; Kohsuke Kudo; Yoshihiro Matsuno; Satoru Wakasa; Toshihisa Anzai
  Circulation journal : official journal of the Japanese Circulation Society, 88, 6, 1008, 1008, 2024年05月24日, ［査読有り］, ［国内誌］
  英語, 研究論文（学術雑誌）
• Exploratory analysis of the accuracy of echocardiographic parameters for the assessment of right ventricular function and right ventricular-pulmonary artery coupling.
  Hideki Shima; Ichizo Tsujino; Junichi Nakamura; Toshitaka Nakaya; Ayako Sugimoto; Takahiro Sato; Taku Watanabe; Hiroshi Ohira; Masaru Suzuki; Satonori Tsuneta; Yasuyuki Chiba; Michito Murayama; Isao Yokota; Satoshi Konno
  Pulmonary circulation, 14, 2, e12368, 2024年04月21日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, Echocardiography is a widely used modality for the assessment of right ventricular (RV) function; however, few studies have comprehensively compared the accuracy of echocardiographic parameters using invasively obtained reference values. Therefore, this exploratory study aimed to compare the accuracy of echocardiographic parameters of RV function and RV-pulmonary artery (PA) coupling. We calculated four indices of RV function (end-systolic elastance [Ees] for systolic function [contractility], τ for relaxation, and β and end-diastolic elastance [Eed] for stiffness), and an index of RV-PA coupling (Ees/arterial elastance [Ea]), using pressure catheterization, cardiac magnetic resonance imaging, and a single-beat method. We then compared the correlations of RV indices with echocardiographic parameters. In 63 participants (54 with pulmonary hypertension (PH) and nine without PH), Ees and τ correlated with several echocardiographic parameters, such as RV diameter and area, but the correlations were moderate (|correlation coefficients (ρ)| < 0.5 for all parameters). The correlations of β and Eed with echocardiographic parameters were weak, with |ρ| < 0.4. In contrast, Ees/Ea closely correlated with RV free wall longitudinal strain (RVFW-LS)/estimated systolic PA pressure (eSPAP) (ρ = -0.72). Ees/Ea also correlated with tricuspid annular plane systolic excursion/eSPAP, RV diameter, and RV end-systolic area, with |ρ | >0.65. In addition, RVFW-LS/eSPAP yielded high sensitivity (0.84) and specificity (0.75) for detecting reduced Ees/Ea. The present study indicated a limited accuracy of echocardiographic parameters in assessing RV systolic and diastolic function. In contrast to RV function, they showed high accuracy for assessing RV-PA coupling, with RVFW-LS/eSPAP exhibiting the highest accuracy.
• Deep learning to assess right ventricular ejection fraction from two-dimensional echocardiograms in precapillary pulmonary hypertension.
  Michito Murayama; Hiroyuki Sugimori; Takaaki Yoshimura; Sanae Kaga; Hideki Shima; Satonori Tsuneta; Aoi Mukai; Yui Nagai; Shinobu Yokoyama; Hisao Nishino; Junichi Nakamura; Takahiro Sato; Ichizo Tsujino
  Echocardiography (Mount Kisco, N.Y.), 41, 4, e15812, 2024年04月17日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Precapillary pulmonary hypertension (PH) is characterized by a sustained increase in right ventricular (RV) afterload, impairing systolic function. Two-dimensional (2D) echocardiography is the most performed cardiac imaging tool to assess RV systolic function; however, an accurate evaluation requires expertise. We aimed to develop a fully automated deep learning (DL)-based tool to estimate the RV ejection fraction (RVEF) from 2D echocardiographic videos of apical four-chamber views in patients with precapillary PH. METHODS: We identified 85 patients with suspected precapillary PH who underwent cardiac magnetic resonance imaging (MRI) and echocardiography. The data was divided into training (80%) and testing (20%) datasets, and a regression model was constructed using 3D-ResNet50. Accuracy was assessed using five-fold cross validation. RESULTS: The DL model predicted the cardiac MRI-derived RVEF with a mean absolute error of 7.67%. The DL model identified severe RV systolic dysfunction (defined as cardiac MRI-derived RVEF < 37%) with an area under the curve (AUC) of .84, which was comparable to the AUC of RV fractional area change (FAC) and tricuspid annular plane systolic excursion (TAPSE) measured by experienced sonographers (.87 and .72, respectively). To detect mild RV systolic dysfunction (defined as RVEF ≤ 45%), the AUC from the DL-predicted RVEF also demonstrated a high discriminatory power of .87, comparable to that of FAC (.90), and significantly higher than that of TAPSE (.67). CONCLUSION: The fully automated DL-based tool using 2D echocardiography could accurately estimate RVEF and exhibited a diagnostic performance for RV systolic dysfunction comparable to that of human readers.
• Comparison of Echo-Planar Imaging and Compressed Sensing in the Estimation of Flow Metrics from Aortic 4D Flow MR Imaging: A Healthy Volunteer Study.
  Satoru Aono; Satonori Tsuneta; Noriko Nishioka; Takuya Aoike; Hiroyuki Hirayama; Kinya Ishizaka; Jihun Kwon; Masami Yoneyama; Noriyuki Fujima; Kohsuke Kudo
  Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2024年03月29日, ［査読有り］, ［責任著者］, ［国内誌］
  英語, 研究論文（学術雑誌）, PURPOSE: Prolonged scanning of time-resolved 3D phase-contrast MRI (4D flow MRI) limits its routine use in clinical practice. An echo-planar imaging (EPI)-based sequence and compressed sensing can reduce the scan duration. We aimed to determine the impact of EPI for 4D flow MRI on the scan duration, image quality, and quantitative flow metrics. METHODS: This was a prospective study of 15 healthy volunteers (all male, mean age 33 ± 5 years). Conventional sensitivity encoding (SENSE), EPI with SENSE (EPI), and compressed SENSE (CS) (reduction factors: 6 and 12, respectively) were scanned.Scan duration, qualitative indexes of image quality, and quantitative flow parameters of net flow volume, maximum flow velocity, wall shear stress (WSS), and energy loss (EL) in the ascending aorta were assessed. Two-dimensional phase-contrast cine MRI (2D-PC) was considered the gold standard of net flow volume and maximum flow velocity. RESULTS: Compared to SENSE, EPI and CS12 shortened scan durations by 71% and 73% (EPI, 4 min 39 sec; CS6, 7 min 29 sec; CS12, 4 min 14 sec; and SENSE, 15 min 51 sec). Visual image quality was significantly better for EPI than for SENSE and CS (P < 0.001). The net flow volumes obtained with SENSE, EPI, and CS12 and those obtained with 2D-PC were correlated well (r = 0.950, 0.871, and 0.850, respectively). However, the maximum velocity obtained with EPI was significantly underestimated (P < 0.010). The average WSS was significantly higher with EPI than with SENSE, CS6, and CS12 (P < 0.001, P = 0.040, and P = 0.012, respectively). The EL was significantly lower with EPI than with CS6 and CS12 (P = 0.002 and P = 0.007, respectively). CONCLUSION: EPI reduced the scan duration, improved visual image quality, and was associated with more accurate net flow volume than CS. However, the flow velocity, WSS, and EL values obtained with EPI and other sequences may not be directly comparable.
• Echocardiographic estimation of right ventricular diastolic stiffness based on pulmonary regurgitant velocity waveform analysis in precapillary pulmonary hypertension.
  Yui Nagai; Michito Murayama; Sanae Kaga; Hideki Shima; Satonori Tsuneta; Shinobu Yokoyama; Hisao Nishino; Mana Goto; Yukino Suzuki; Yusuke Yanagi; Suguru Ishizaka; Hiroyuki Iwano; Junichi Nakamura; Takahiro Sato; Ichizo Tsujino
  The international journal of cardiovascular imaging, 2024年03月27日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, Right ventricular (RV) diastolic stiffness is an independent predictor of survival and is strongly associated with disease severity in patients with precapillary pulmonary hypertension (PH). Therefore, a fully validated echocardiographic method for assessing RV diastolic stiffness needs to be established. This study aimed to compare echocardiography-derived RV diastolic stiffness and invasively measured pressure-volume loop-derived RV diastolic stiffness in patients with precapillary PH. We studied 50 consecutive patients with suspected or confirmed precapillary PH who underwent cardiac catheterization, magnetic resonance imaging, and echocardiography within a 1-week interval. Single-beat RV pressure-volume analysis was performed to determine the gold standard for RV diastolic stiffness. Elevated RV end-diastolic pressure (RVEDP) was defined as RVEDP ≥ 8 mmHg. Using continuous-wave Doppler and M-mode echocardiography, an echocardiographic index of RV diastolic stiffness was calculated as the ratio of the atrial-systolic descent of the pulmonary artery-RV pressure gradient derived from pulmonary regurgitant velocity (PRPGDAC) to the tricuspid annular plane movement during atrial contraction (TAPMAC). PRPGDAC/TAPMAC showed significant correlation with β (r = 0.54, p < 0.001) and RVEDP (r = 0.61, p < 0.001). A cut-off value of 0.74 mmHg/mm for PRPGDAC/TAPMAC showed 83% sensitivity and 93% specificity for identifying elevated RVEDP. Multivariate analyses indicated that PRPGDAC/TAPMAC was independently associated with disease severity in patients with precapillary PH, including substantial PH symptoms, stroke volume index, right atrial size, and pressure. PRPGDAC/TAPMAC, based on pulmonary regurgitation velocity waveform analysis, is useful for the noninvasive assessment of RV diastolic stiffness and is associated with prognostic risk factors in precapillary PH.
• Prognostic Value of Combined Assessments of Late Gadolinium Enhancement and Fluorodeoxyglucose Uptake in Cardiac Sarcoidosis.
  Sho Kazui; Sakae Takenaka; Toshiyuki Nagai; Satonori Tsuneta; Kenji Hirata; Yoshiya Kato; Hirokazu Komoriyama; Yuta Kobayashi; Akinori Takahashi; Kiwamu Kamiya; Taro Temma; Takuma Sato; Atsushi Tada; Yutaro Yasui; Michikazu Nakai; Takahiro Sato; Ichizo Tsujino; Kohsuke Kudo; Satoshi Konno; Toshihisa Anzai
  JACC. Cardiovascular imaging, 2024年03月11日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）
• 術前検査で偶発的に発見されたMinute pulmonary meningothelial-like nodulesの1例
  小林 圭太; 吉川 仁人; 高柳 歩; 常田 慧徳; 中川 純一; 木村 理奈; 西岡 典子; 坂本 圭太; 加藤 扶美; 岡崎 ななせ; 松野 吉宏; 氏家 秀樹; 工藤 與亮
  北海道放射線医学雑誌, 4, 25, 29, (NPO)メディカルイメージラボ, 2024年03月, ［査読有り］
  日本語
• Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery
  Satonori Tsuneta
  PHYSIOLOGICAL REPORTS, 2024年03月, ［査読有り］
  研究論文（学術雑誌）
• Accumulation of Technetium-99m Tetrofosmin on Myocardial Perfusion Scintigraphy in a Patient With Immunoglobulin G4-Related Coronary Periarteritis
  Satonori Tsuneta
  CANADIAN JOURNAL OF CARDIOLOGY, 40, 3, 450, 451, 2024年03月, ［査読有り］, ［筆頭著者, 責任著者］
  英語, 研究論文（学術雑誌）
• Gastrointestinal: Solid pseudopapillary neoplasm of the pancreas with high-grade malignant transformation
  Satonori Tsuneta
  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 39, 619, 619, 2024年01月15日, ［査読有り］
  研究論文（学術雑誌）
• Biopsy-proven cardiac sarcoidosis mimicking apical hypertrophic cardiomyopathy
  Kei Kawakami; Kazunori Omote; Satonori Tsuneta; Toshiyuki Nagai; Toshihisa Anzai
  European Heart Journal Cardiovascular Imaging, 25, 1, E57, 2024年01月01日, ［査読有り］
• Focal myocarditis associated with immune checkpoint inhibitor therapy
  Mizuki Hayashizaki; Kazunori Omote; Satonori Tsuneta; Toshiyuki Nagai; Toshihisa Anzai
  European Heart Journal Cardiovascular Imaging, 24, 12, E308, 2023年12月01日, ［査読有り］
• Differences in blood flow dynamics between balloon- and self-expandable valves in patients with aortic stenosis undergoing transcatheter aortic valve replacement.
  Yuki Takahashi; Kiwamu Kamiya; Toshiyuki Nagai; Satonori Tsuneta; Noriko Oyama-Manabe; Takeshi Hamaya; Sho Kazui; Yutaro Yasui; Kohei Saiin; Seiichiro Naito; Yoshifumi Mizuguchi; Sakae Takenaka; Atsushi Tada; Suguru Ishizaka; Yuta Kobayashi; Kazunori Omote; Takuma Sato; Yasushige Shingu; Kohsuke Kudo; Satoru Wakasa; Toshihisa Anzai
  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 25, 1, 60, 60, 2023年10月26日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: The differences in pre- and early post-procedural blood flow dynamics between the two major types of bioprosthetic valves, the balloon-expandable valve (BEV) and self-expandable valve (SEV), in patients with aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR), have not been investigated. We aimed to investigate the differences in blood flow dynamics between the BEV and SEV using four-dimensional flow cardiovascular magnetic resonance (4D flow CMR). METHODS: We prospectively examined 98 consecutive patients with severe AS who underwent TAVR between May 2018 and November 2021 (58 BEV and 40 SEV) after excluding those without CMR because of a contraindication, inadequate imaging from the analyses, or patients' refusal. CMR was performed in all participants before (median interval, 22 [interquartile range (IQR) 4-39] days) and after (median interval, 6 [IQR 3-6] days) TAVR. We compared the changes in blood flow patterns, wall shear stress (WSS), and energy loss (EL) in the ascending aorta (AAo) between the BEV and SEV using 4D flow CMR. RESULTS: The absolute reductions in helical flow and flow eccentricity were significantly higher in the SEV group compared in the BEV group after TAVR (BEV: - 0.22 ± 0.86 vs. SEV: - 0.85 ± 0.80, P < 0.001 and BEV: - 0.11 ± 0.79 vs. SEV: - 0.50 ± 0.88, P = 0.037, respectively); there were no significant differences in vortical flow between the groups. The absolute reduction of average WSS was significantly higher in the SEV group compared to the BEV group after TAVR (BEV: - 0.6 [- 2.1 to 0.5] Pa vs. SEV: - 1.8 [- 3.5 to - 0.8] Pa, P = 0.006). The systolic EL in the AAo significantly decreased after TAVR in both the groups, while the absolute reduction was comparable between the groups. CONCLUSIONS: Helical flow, flow eccentricity, and average WSS in the AAo were significantly decreased after SEV implantation compared to BEV implantation, providing functional insights for valve selection in patients with AS undergoing TAVR. Our findings offer valuable insights into blood flow dynamics, aiding in the selection of valves for patients with AS undergoing TAVR. Further larger-scale studies are warranted to confirm the prognostic significance of hemodynamic changes in these patients.
• Prognostic Value of Liver Fibrotic Markers in Patients With Heart Failure.
  Atsushi Tada; Toshiyuki Nagai; Yoshiya Kato; Noriko Oyama-Manabe; Satonori Tsuneta; Michikazu Nakai; Yutaro Yasui; Sho Kazui; Yuki Takahashi; Kohei Saiin; Seiichiro Naito; Sakae Takenaka; Yoshifumi Mizuguchi; Yuta Kobayashi; Suguru Ishizaka; Kazunori Omote; Takuma Sato; Takao Konishi; Kiwamu Kamiya; Kohsuke Kudo; Toshihisa Anzai
  The American journal of cardiology, 200, 115, 123, 2023年06月10日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, Several liver fibrotic markers are associated with prognosis in patients with heart failure (HF). However, the optimal markers for outcome prediction remain unclear. This study aimed to simultaneously investigate the prognostic value of liver fibrotic markers and the associations between these markers and clinical parameters in patients with HF without organic liver disease. We prospectively examined 211 consecutive patients with chronic HF between April 2018 and August 2021, excluding those with organic liver disease, using liver magnetic resonance imaging and ultrasound. A total of 7 representative liver fibrotic markers were measured in all patients. The primary outcome of interest was the composite of all-cause death and hospitalization for worsening HF. During a median follow-up period of 747 (interquartile range 465 to 1,042) days, the primary outcome occurred in 45 patients. Patients with higher hyaluronic acid and type III procollagen N-terminal peptide (P-III-P) levels showed a significantly higher incidence of the primary outcome than those without (p <0.001 and p = 0.005, respectively). The multivariable Cox regression analysis revealed that hyaluronic acid and P-III-P levels were independently associated with the risk of adverse events (hazard ratio 1.84, 95% confidence interval 1.18 to 2.87 and hazard ratio 2.89, 95% confidence interval 1.32 to 6.34, respectively) even after adjustment for a mortality prediction model, whereas the other 5 markers were not associated with the primary outcome. In conclusion, among the representative liver fibrotic markers, hyaluronic acid and P-III-P might be the optimal markers for outcome prediction in patients with HF.
• Clinical utility of single-shot echo-planar diffusion-weighted imaging using L1-regularized iterative sensitivity encoding in prostate MRI.
  Noriko Nishioka; Noriyuki Fujima; Satonori Tsuneta; Masami Yoneyama; Ryuji Matsumoto; Takashige Abe; Rina Kimura; Keita Sakamoto; Fumi Kato; Kohsuke Kudo
  Medicine, 102, 17, e33639, 2023年04月25日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, We investigated the ability of echo-planar imaging with L1-regularized iterative sensitivity encoding-based diffusion-weighted imaging (DWI) to improve the image quality and reduce the scanning time in prostate magnetic resonance imaging. We retrospectively analyzed 109 cases of prostate magnetic resonance imaging. We compared variables in the quantitative and qualitative assessments among 3 imaging groups: conventional parallel imaging-based DWI (PI-DWI) with an acquisition time of 3 minutes 15 seconds; echo-planar imaging with L1-regularized iterative sensitivity encoding-based DWI (L1-DWI) with a normal acquisition time (L1-DWINEX12) of 3 minutes 15 seconds; and L1-DWI with a half acquisition time (L1-DWINEX6) of 1 minute 45 seconds. As a quantitative assessment, the signal-to-noise ratio (SNR) of DWI (SNR-DWI), the contrast-to-noise ratio (CNR) of DWI (CNR-DWI), and the CNR of apparent diffusion coefficient were measured. As a qualitative assessment, the image quality and visual detectability of prostate carcinoma were evaluated. In the quantitative analysis, L1-DWINEX12 showed significantly higher SNR-DWI than PI-DWI (P = .0058) and L1-DWINEX6 (P < .0001). In the qualitative analysis, the image quality score for L1-DWINEX12 was significantly higher than those of PI-DWI and L1-DWINEX6. A non-inferiority assessment demonstrated that L1-DWINEX6 was non-inferior to PI-DWI in terms of both quantitative CNR-DWI and qualitative grading of image quality with a <20% inferior margin. L1-DWI successfully demonstrated a reduced scanning time while maintaining good image quality.
• Clinical and Hemodynamic Responses to Imatinib in Pulmonary Veno-Occlusive Disease/Pulmonary Capillary Hemangiomatosis: A Retrospective Pilot Study of Five Cases and Review of the Literature
  Junichi Nakamura; Ichizo Tsujino; Hideki Shima; Toshitaka Nakaya; Ayako Sugimoto; Takahiro Sato; Taku Watanabe; Hiroshi Ohira; Masaru Suzuki; Satonori Tsuneta; Ryo Hisada; Masaru Kato; Satoshi Konno
  American Journal of Cardiovascular Drugs, 23, 3, 329, 338, Springer Science and Business Media LLC, 2023年03月30日, ［査読有り］
  研究論文（学術雑誌）
• Impact of right ventricular stiffness on discordance between hemodynamic parameter and regurgitant volume in patients with pulmonary regurgitation.
  Ko Motoi; Hiroyuki Iwano; Satonori Tsuneta; Suguru Ishizaka; Yoji Tamaki; Hiroyuki Aoyagi; Kosuke Nakamura; Michito Murayama; Masahiro Nakabachi; Shinobu Yokoyama; Hisao Nishino; Sanae Kaga; Atsuhito Takeda; Toshihisa Anzai
  The international journal of cardiovascular imaging, 39, 6, 1133, 1142, 2023年03月17日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Accurate detection of significant pulmonary regurgitation (PR) is critical in management of patients after right ventricular (RV) outflow reconstruction in Tetralogy of Fallot (TOF) patients, because of its influence on adverse outcomes. Although pressure half time (PHT) of PR velocity is one of the widely used echocardiographic markers of the severity, shortened PHT is suggested to be seen in conditions with increased RV stiffness with mild PR. However, little has been reported about the exact characteristics of patients showing discrepancy between PHT and PR volume in this population. METHODS: Echocardiography and cardiac magnetic resonance imaging (MRI) were performed in 74 TOF patients after right ventricular outflow tract (RVOT) reconstruction [32 ± 10 years old]. PHT was measured from the continuous Doppler PR flow velocity profile and PHT < 100 ms was used as a sign of significant PR. Presence of end-diastolic RVOT forward flow was defined as RV restrictive physiology. By using phase-contrast MRI, forward and regurgitant volumes through the RVOT were measured and regurgitation fraction was calculated. Significant PR was defined as regurgitant fraction ≥ 25%. RESULTS: Significant PR was observed in 54 of 74 patients. While PHT < 100 ms well predicted significant PR with sensitivity of 96%, specificity of 52%, and c-index of 0.72, 10 patients showed shortened PHT despite regurgitant fraction < 25% (discordant group). Tricuspid annular plane systolic excursion and left ventricular (LV) ejection fraction were comparable between discordant group and patients showing PHT < 100 ms and regurgitant fraction ≥ 25% (concordant group). However, discordant group showed significantly smaller mid RV diameter (30.7 ± 4.5 vs. 39.2 ± 7.3 mm, P < 0.001) and higher prevalence of restrictive physiology (100% vs. 42%, P < 0.01) than concordant group. When mid RV diameter ≥ 32 mm and presence of restrictive physiology were added to PHT, the predictive value was significantly improved (sensitivity: 81%, specificity: 90%, and c-index: 0.89, P < 0.001 vs. PHT alone by multivariable logistic regression model). CONCLUSION: Patients with increased RV stiffness and non-enlarged right ventricle showed short PHT despite mild PR. Although it has been expected, this was the first study to demonstrate the exact characteristics of patients showing discrepancy between PHT and PR volume in TOF patients after RVOT reconstruction.
• 胸膜孤立性線維性腫瘍に合併したDoege-potter症候群の一例
  村本 朋之; 中川 純一; 常田 慧徳; 高橋 文也; 木村 理奈; 西岡 典子; 坂本 圭太; 加藤 扶美; 氏家 秀樹; 加藤 達哉; 大藤 悠理; 亀田 啓; 中村 昭伸; 若林 健人; 松野 吉宏; 工藤 與亮
  北海道放射線医学雑誌, 3, 28, 32, (NPO)メディカルイメージラボ, 2023年03月, ［査読有り］
  日本語
• Fragmented QRS on 12-lead electrocardiogram predicts long-term prognosis in patients with cardiac sarcoidosis.
  Hikaru Hagiwara; Masaya Watanabe; Takahide Kadosaka; Takuya Koizumi; Yuta Kobayashi; Taro Koya; Motoki Nakao; Satonori Tsuneta; Yoshiya Kato; Hirokazu Komoriyama; Rui Kamada; Toshiyuki Nagai; Kohsuke Kudo; Toshihisa Anzai
  Heart and vessels, 2023年01月13日, ［査読有り］, ［国内誌］
  英語, 研究論文（学術雑誌）, Fragmented QRS (fQRS) on a 12-lead electrocardiogram is a known marker of fatal arrhythmias or cardiac adverse events in ischemic and non-ischemic cardiomyopathy patients. Nonetheless, the association between fQRS and clinical outcomes in patients with cardiac sarcoidosis (CS) remains unclear. Herein, we investigated whether fQRS is associated with long-term clinical outcomes in CS patients. A total of 78 patients who received immunosuppressive therapy (IST) for clinically diagnosed CS were retrospectively examined. Patients were classified into two groups according to the presence (n = 19) or absence (n = 59) of fQRS on electrocardiogram before IST. The primary outcome was the composite event of all-cause death, ventricular tachyarrhythmias (VTs), and hospitalization for heart failure. Results of late gadolinium enhancement on cardiac magnetic resonance imaging were also analyzed. During a median follow-up period of 3.7 years (interquartile range: 1.6-6.2 years), the primary outcome occurred more frequently in patients with fQRS than in those without (47% vs. 13%, log-rank p = 0.002). Multivariable Cox regression analyses showed that fQRS was an independent determinant of the primary outcome. The incidence of VTs, within 12 months of IST initiation, was comparable between the two groups; however, late-onset VTs, defined as those occurring ≥ 12 months after IST initiation, occurred more frequently in the fQRS group (21% vs. 2%, log-rank p = 0.002). The scar zone and scar border zone were greater in patients with fQRS than in those without it. In conclusion, our analysis suggests that fQRS is an independent predictor of adverse events, particularly late-onset VTs, in patients with CS.
• Beneficial effects of nintedanib on cardiomyopathy in patients with systemic sclerosis: a pilot study.
  Keita Ninagawa; Masaru Kato; Satonori Tsuneta; Suguru Ishizaka; Hideyuki Ujiie; Ryo Hisada; Michihito Kono; Yuichiro Fujieda; Yoichi M Ito; Tatsuya Atsumi
  Rheumatology (Oxford, England), 62, 7, 2550, 2555, 2022年12月02日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, OBJECTIVES: Nintedanib is an inhibitor of tyrosine kinases that has been shown to slow the progression of interstitial lung disease (ILD), including ILD associated with systemic sclerosis (SSc). The aim of this study was to explore the effect of nintedanib on cardiomyopathy associated with SSc. METHODS: Twenty consecutively hospitalized patients with SSc-ILD were enrolled and prospectively followed. The rate of change at six months in cardiac magnetic resonance (CMR) parametric mapping, including myocardial extracellular volume, was primarily evaluated. Other endpoints included changes in CMR functional parameters, echocardiographic parameters, modified Rodnan skin score, serum biomarkers, and pulmonary function test. RESULTS: Nintedanib was administered in 10 patients, whereas the other 10 were treated without nintedanib or watched, according to ILD severity and progression. Baseline values of CMR parametric mapping were not different between the two groups. The rate of change at six months in myocardial extracellular volume was largely different, almost divergent between the nintedanib group and the control group (-1.62% vs. +2.00%, p= 0.0001). Among other endpoints, the change in right ventricular ejection fraction was significantly different between the two groups (p= 0.02), with a preferential change in the nintedanib group. CONCLUSION: Our data indicate beneficial signals of nintedanib on cardiomyopathy associated with SSc. The anti-fibrotic effect of nintedanib might not be limited to the lung.
• Liver stiffness assessed by magnetic resonance elastography predicts clinical outcomes in patients with heart failure and without chronic liver disease.
  Atsushi Tada; Toshiyuki Nagai; Yoshiya Kato; Kazunori Omote; Noriko Oyama-Manabe; Satonori Tsuneta; Yusuke Kudo; Mutsumi Nishida; Michikazu Nakai; Yuki Takahashi; Kohei Saiin; Seiichiro Naito; Yuta Kobayashi; Sakae Takenaka; Yoshifumi Mizuguchi; Kiwamu Kamiya; Takao Konishi; Takuma Sato; Kohsuke Kudo; Toshihisa Anzai
  European radiology, 33, 3, 2062, 2074, 2022年11月03日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, OBJECTIVES: Evaluation of liver stiffness (LS) by magnetic resonance elastography (MRE) is useful for estimating right atrial pressure (RAP) in patients with heart failure (HF). However, its prognostic implications are unclear. We sought to investigate whether LS measured by MRE (LS-MRE) could predict clinical outcomes in patients with HF. METHODS: We prospectively examined 207 consecutive HF patients between April 2018 and May 2021 after excluding those with organic liver disease. All patients underwent 3.0-T MRE. The primary outcome of interest was the composite of all-cause death and hospitalisation for HF. RESULTS: During a median follow-up period of 720 (interquartile range [IQR] 434-1013) days, the primary outcome occurred in 44 patients (21%), including 15 (7%) all-cause deaths and 29 (14%) hospitalisations for HF. The patients were divided into two groups according to median LS-MRE of 2.54 (IQR 2.34-2.82) kPa. Patients with higher LS-MRE showed a higher incidence of the primary outcome compared to those with lower LS-MRE (p < 0.001). Multivariable Cox regression analyses revealed that LS-MRE value was independently associated with the risk of adverse events (hazard ratio 2.49, 95% confidence interval 1.46-4.24). In multivariable linear regression, RAP showed a stronger correlation with LS-MRE (β coefficient = 0.31, p < 0.001) compared to markers related to liver fibrosis. CONCLUSIONS: In patients without chronic liver disease and presenting with HF, elevated LS-MRE was independently associated with worse clinical outcomes. Elevated LS-MRE may be useful for risk stratification in patients with HF and without chronic liver disease. KEY POINTS: • Magnetic resonance elastography (MRE) is an emerging non-invasive imaging technique for evaluating liver stiffness (LS) which can estimate right atrial pressure. • Elevated LS-MRE, which mainly reflects liver congestion, was independently associated with worse clinical outcomes in patients with heart failure. • The assessment of LS-MRE would be useful for stratifying the risk of adverse events in heart failure patients without chronic liver disease.
• Efficacy and safety of oral pulmonary vasodilators in pulmonary veno‐occlusive disease
  Junichi Nakamura; Ichizo Tsujino; Hideki Shima; Toshitaka Nakaya; Ayako Sugimoto; Takahiro Sato; Taku Watanabe; Hiroshi Ohira; Masaru Suzuki; Satonori Tsuneta; Ryo Hisada; Masaru Kato; Satoshi Konno
  Pulmonary Circulation, 12, 4, e12168, e12168, Wiley, 2022年10月, ［査読有り］
  研究論文（学術雑誌）
• Utility of the deep learning technique for the diagnosis of orbital invasion on CT in patients with a nasal or sinonasal tumor.
  Junichi Nakagawa; Noriyuki Fujima; Kenji Hirata; Minghui Tang; Satonori Tsuneta; Jun Suzuki; Taisuke Harada; Yohei Ikebe; Akihiro Homma; Satoshi Kano; Kazuyuki Minowa; Kohsuke Kudo
  Cancer imaging : the official publication of the International Cancer Imaging Society, 22, 1, 52, 52, 2022年09月22日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: In nasal or sinonasal tumors, orbital invasion beyond periorbita by the tumor is one of the important criteria in the selection of the surgical procedure. We investigated the usefulness of the convolutional neural network (CNN)-based deep learning technique for the diagnosis of orbital invasion, using computed tomography (CT) images. METHODS: A total of 168 lesions with malignant nasal or sinonasal tumors were divided into a training dataset (n = 119) and a test dataset (n = 49). The final diagnosis (invasion-positive or -negative) was determined by experienced radiologists who carefully reviewed all of the CT images. In a CNN-based deep learning analysis, a slice of the square target region that included the orbital bone wall was extracted and fed into a deep-learning training session to create a diagnostic model using transfer learning with the Visual Geometry Group 16 (VGG16) model. The test dataset was subsequently tested in CNN-based diagnostic models and by two other radiologists who were not specialized in head and neck radiology. At approx. 2 months after the first reading session, two radiologists again reviewed all of the images in the test dataset, referring to the diagnoses provided by the trained CNN-based diagnostic model. RESULTS: The diagnostic accuracy was 0.92 by the CNN-based diagnostic models, whereas the diagnostic accuracies by the two radiologists at the first reading session were 0.49 and 0.45, respectively. In the second reading session by two radiologists (diagnosing with the assistance by the CNN-based diagnostic model), marked elevations of the diagnostic accuracy were observed (0.94 and 1.00, respectively). CONCLUSION: The CNN-based deep learning technique can be a useful support tool in assessing the presence of orbital invasion on CT images, especially for non-specialized radiologists.
• Determinants of exercise capacity in patients with heart failure without left ventricular hypertrophy.
  Suguru Ishizaka; Hiroyuki Iwano; Shingo Tsujinaga; Michito Murayama; Satonori Tsuneta; Hiroyuki Aoyagi; Yoji Tamaki; Ko Motoi; Yasuyuki Chiba; Asuka Tanemura; Masahiro Nakabachi; Shinobu Yokoyama; Hisao Nishino; Kazunori Okada; Brett A Meyers; Pavlos P Vlachos; Takuma Sato; Kiwamu Kamiya; Masaya Watanabe; Sanae Kaga; Toshiyuki Nagai; Noriko Oyama-Manabe; Toshihisa Anzai
  Journal of cardiology, 81, 1, 33, 41, 2022年09月16日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Determinants of exercise intolerance in a phenotype of heart failure with preserved ejection fraction (HFpEF) with normal left ventricular (LV) structure have not been fully elucidated. METHODS: Cardiopulmonary exercise testing and exercise-stress echocardiography were performed in 44 HFpEF patients without LV hypertrophy. Exercise capacity was determined by peak oxygen consumption (peak VO2). Doppler-derived cardiac output (CO), transmitral E velocity, systolic (LV-s') and early diastolic mitral annular velocities (e'), systolic pulmonary artery (PA) pressure (SPAP), tricuspid annular plane systolic excursion (TAPSE), and peak systolic right ventricular (RV) free wall velocity (RV-s') were measured at rest and exercise. E/e' and TAPSE/SPAP were used as an LV filling pressure parameter and RV-PA coupling, respectively. RESULTS: During exercise, CO, LV-s', RV-s', e', and SPAP were significantly increased (p < 0.05 for all), whereas E/e' remained unchanged and TAPSE/SPAP was significantly reduced (p < 0.001). SPAP was higher and TAPSE/SPAP was lower at peak exercise in patients showing lower-half peak VO2. In univariable analyses, LV-s' (R = 0.35, p = 0.022), SPAP (R = -0.40, p = 0.008), RV-s' (R = 0.47, p = 0.002), and TAPSE/SPAP (R = 0.42, p = 0.005) were significantly correlated with peak VO2. In multivariable analyses, not only SPAP, but also TAPSE/SPAP independently determined peak VO2 even after the adjustment for clinically relevant parameters. CONCLUSIONS: In HFpEF patients without LV hypertrophy, altered RV-PA coupling by exercise could be associated with exercise intolerance, which might not be caused by elevated LV filling pressure.
• Phase I Randomized Trial of 17 O-Labeled Water: Safety and Feasibility Study of Indirect Proton MRI for the Evaluation of Cerebral Water Dynamics.
  Taisuke Harada; Kohsuke Kudo; Hiroyuki Kameda; Ryota Sato; Toru Shirai; Yoshitaka Bito; Noriyuki Fujima; Satonori Tsuneta; Toshifumi Nogawa; Kenichiro Maeda; Hiroshi Hayashi; Makoto Sasaki
  Journal of magnetic resonance imaging : JMRI, 56, 6, 1874, 1882, 2022年04月30日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: 17 O-labeled water (PSO17) is a contrast agent developed to measure brain water dynamics and cerebral blood flow. PURPOSE: To evaluate the safety and feasibility of PSO17. STUDY TYPE: Prospective study. SUBJECTS: A total of 12 male healthy volunteers (23.1 ± 1.9 years) were assigned to three groups of four subjects: placebo (normal saline), PSO17 10%, and PSO17 20%. FIELD STRENGTH/SEQUENCE: Dynamic 3D fluid attenuated inversion recovery (FLAIR, fast spin echo with variable refocusing flip angle) scans of the brain were performed with 3-T MRI. ASSESSMENT: Contrast agents were injected 5 minutes after the start of a 10-minute scan. Any symptoms, vital signs, and blood and urine tests were evaluated at five timepoints from preinjection to 4 days after. Blood samples for pharmacokinetic analysis, including half-life (T1/2), maximum fraction (Cmax ), time-to-maximum fraction (Tmax ), and area under the curve (AUC), were collected at 13 timepoints from preinjection to 168 hours after. Regions of interest were set in the cerebral cortex (CC), basal ganglia/thalamus (BG/TM), and white matter (WM), and 17 O concentrations were calculated from signal changes and evaluated using Cmax . STATISTICAL TESTS: All items were compared among the three groups using Tukey-Kramer's honestly significant difference test. Statistical significance was defined as P < 0.5. RESULTS: No safety issues were noted with the intravenous administration of PSO17. The T1/2 was approximately 160 hours, and the AUCs were 1.77 ± 0.10 and 3.75 ± 0.36 in the PSO17 10% and 20% groups, respectively. 17 O fractions calculated from MRI signals were higher in the PSO17 20% group than in the 10% and placebo groups. Significant differences were noted between all pairs of groups in the CC and BG/TM, and between PSO17 20% and both placebo and 10% groups in the WM. DATA CONCLUSION: PSO17 might be considered safe as a contrast medium. Dynamic 3D-FLAIR might detect dose-dependent signal changes and estimate 17 O. EVIDENCE LEVEL: 1 TECHNICAL EFFICACY: Stage 1.
• Presurgical assessment of flow variability in an azygos vein aneurysm using 4D-flow MRI.
  Takuya Ikushima; Hideki Ujiie; Satonori Tsuneta; Ryohei Chiba; Yukiko Tabata; Aki Fujiwara-Kuroda; Yasuhiro Hida; Kichizo Kaga; Satoru Wakasa; Tatsuya Kato
  General thoracic and cardiovascular surgery, 70, 7, 673, 676, 2022年04月06日, ［査読有り］, ［国内誌］
  英語, 研究論文（学術雑誌）, Azygos vein aneurysm (AVA) is necessary to prevent pulmonary embolism due to the outflow of a thrombus or rupture of the aneurysm. However, there is no established modality to assess the properties of AVA. Time-resolved three-dimensional phase-contrast magnetic resonance imaging (4D-flow MRI) has been used to examine the hemodynamics in various fields. We report a case of AVA to evaluate the flow variability and adhesions of surrounding tissues using 4D-flow MRI. The findings of the study suggested aneurysm turbulence and the absence of thrombi. The cine image, which showed a sliding wall synchronized to the heartbeat, indicated no adhesion to the superior vena cava. Based on these results, the thoracoscopic approach was deemed possible preoperatively. Thoracoscopic AVA resection was performed, and the postoperative course was uneventful. This study documented the utility of 4D-flow MRI for a detailed evaluation of AVA.
• Underdiagnosis of cardiac sarcoidosis by ECG and echocardiography in cases of extracardiac sarcoidosis
  Hiroshi Ohira; Takahiro Sato; Osamu Manabe; Noriko Oyama-Manabe; Akiko Hayashishita; Toshitaka Nakaya; Junichi Nakamura; Naoko Suzuki; Ayako Sugimoto; Sho Furuya; Satonori Tsuneta; Taku Watanabe; Ichizo Tsujino; Satoshi Konno
  ERJ Open Research, 8, 2, 00516, 2021, European Respiratory Society (ERS), 2022年04月, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, Background
  
  Although screening with 12-lead electrocardiography and transthoracic echocardiography for cardiac involvement has been recommended for patients with biopsy-proven extracardiac sarcoidosis, cardiac sarcoidosis has been reported even in patients with normal electrocardiography and echocardiography findings. We investigated the prevalence and characteristics of these patient cohorts.
  
  Methods
  
  We studied 112 consecutive patients (age, 55±17 years, 64% females) with biopsy-proven extracardiac sarcoidosis who had undergone ¹⁸F-fluorodeoxyglucose positron emission tomography and cardiac magnetic resonance imaging for cardiac sarcoidosis evaluation. The patients were categorised as those showing normal findings both in electrocardiography and transthoracic echocardiography (normal group) and those showing abnormal findings in one or both examinations (abnormal group).
  
  Results
  
  33 (29%) and 79 (71%) patients were categorised into the normal and abnormal groups, respectively, of which 6 (18%) and 43 (54%) patients, respectively, were diagnosed with cardiac sarcoidosis (p<0.01). Of these six patients in the normal group, two with multiple-organ sarcoidosis showed clinical deterioration of cardiac involvement and required steroid therapy; three with small cardiac involvement showed natural remission over follow-up assessments; and one underwent steroid therapy and showed an improvement in the left ventricular ejection fraction to within normal limits.
  
  Conclusions
  
  The prevalence of cardiac sarcoidosis in patients with biopsy-proven extracardiac sarcoidosis and normal electrocardiography and transthoracic echocardiography findings was ∼20%. Electrocardiography and transthoracic echocardiography may not detect cardiac sarcoidosis in patients without conduction and morphological abnormalities. However, some of these patients may subsequently show clinically manifested cardiac sarcoidosis. Physicians should be mindful of this population.
• Determinants of altered left ventricular suction in pre-capillary pulmonary hypertension.
  Yasuyuki Chiba; Hiroyuki Iwano; Satonori Tsuneta; Shingo Tsujinaga; Brett Meyers; Pavlos Vlachos; Suguru Ishizaka; Ko Motoi; Hiroyuki Aoyagi; Yoji Tamaki; Asuka Tanemura; Michito Murayama; Shinobu Yokoyama; Masahiro Nakabachi; Hisao Nishino; Sanae Kaga; Kiwamu Kamiya; Hiroshi Ohira; Ichizo Tsujino; Toshihisa Anzai
  European heart journal. Cardiovascular Imaging, 23, 10, 1399, 1406, 2022年01月10日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, AIMS: Although the left ventricular (LV) dysfunction in pre-capillary pulmonary hypertension (PH) has been recently recognized, the mechanism of LV dysfunction in this entity is not completely understood. We thus aimed to elucidate the determinants of intraventricular pressure difference (IVPD), a measure of LV suction, in pre-capillary PH. METHODS AND RESULTS: Right heart catheterization and echocardiography were performed in 86 consecutive patients with pre-capillary PH (57 ± 18 years, 85% female). IVPD was determined using colour M-mode Doppler to integrate the Euler equation. In overall, IVPD was reduced compared to previously reported value in normal subjects. In univariable analyses, QRS duration (P = 0.028), LV ejection fraction (P = 0.006), right ventricular (RV) end-diastolic area (P < 0.001), tricuspid annular plane systolic excursion (P = 0.004), and LV early-diastolic eccentricity index (P = 0.009) were associated with IVPD. In the multivariable analyses, RV end-diastolic area and LV eccentricity index independently determined the IVPD. CONCLUSION: Aberrant ventricular interdependence caused by RV enlargement could impair the LV suction. This study first applied echocardiographic IVPD, a reliable marker of LV diastolic suction, to investigate the mechanism of LV diastolic dysfunction in pre-capillary PH.
• Advances in Diagnostic Imaging for Cardiac Sarcoidosis.
  Osamu Manabe; Noriko Oyama-Manabe; Tadao Aikawa; Satonori Tsuneta; Nagara Tamaki
  Journal of clinical medicine, 10, 24, 2021年12月11日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, Sarcoidosis is a systemic granulomatous disease of unknown etiology, and its clinical presentation depends on the affected organ. Cardiac sarcoidosis (CS) is one of the leading causes of death among patients with sarcoidosis. The clinical manifestations of CS are heterogeneous, and range from asymptomatic to life-threatening arrhythmias and progressive heart failure due to the extent and location of granulomatous inflammation in the myocardium. Advances in imaging techniques have played a pivotal role in the evaluation of CS because histological diagnoses obtained by myocardial biopsy tend to have lower sensitivity. The diagnosis of CS is challenging, and several approaches, notably those using positron emission tomography and cardiac magnetic resonance imaging (MRI), have been reported. Delayed-enhanced computed tomography (CT) may also be used for diagnosing CS in patients with MRI-incompatible devices and allows acceptable evaluation of myocardial hyperenhancement in such patients. This article reviews the advances in imaging techniques for the evaluation of CS.
• Association of high serum soluble interleukin 2 receptor levels with risk of adverse events in cardiac sarcoidosis.
  Yuta Kobayashi; Takuma Sato; Toshiyuki Nagai; Kenji Hirata; Satonori Tsuneta; Yoshiya Kato; Hirokazu Komoriyama; Kiwamu Kamiya; Takao Konishi; Kazunori Omote; Hiroshi Ohira; Kohsuke Kudo; Satoshi Konno; Toshihisa Anzai
  ESC heart failure, 8, 6, 5282, 5292, 2021年09月12日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, AIMS: Although soluble interleukin 2 receptor (sIL-2R) is a potentially useful biomarker in the diagnosis and evaluation of disease severity in patients with sarcoidosis, its prognostic implication in patients with cardiac sarcoidosis (CS) is unclear. We sought to investigate whether sIL-2R was associated with clinical outcomes and to clarify the relationship between sIL-2R levels and disease activity in patients with CS. METHODS AND RESULTS: We examined 83 consecutive patients with CS in our hospital who had available serum sIL-2R data between May 2003 and February 2020. The primary outcome was a composite of advanced atrioventricular block, ventricular tachycardia or ventricular fibrillation, heart failure hospitalization, and all-cause death. Inflammatory activity in the myocardium and lymph nodes was assessed by 18 F-fluorideoxyglucose positron emission tomography/computed tomography. During a median follow-up period of 2.96 (IQR 2.24-4.27) years, the primary outcome occurred in 24 patients (29%). Higher serum sIL-2R levels (>538 U/mL, the median) were significantly related to increased incidence of primary outcome (P = 0.037). Multivariable Cox regression analysis showed that a higher sIL-2R was independently associated with an increased subsequent risk of adverse events (HR 3.71, 95% CI 1.63-8.44, P = 0.002), even after adjustment for significant covariates. sIL-2R levels were significantly correlated to inflammatory activity in lymph nodes (r = 0.346, P = 0.003) but not the myocardium (r = 0.131, P = 0.27). CONCLUSIONS: Increased sIL-2R is associated with worse long-term clinical outcomes accompanied by increased systemic inflammatory activity in CS patients.
• Myocardial T1-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience.
  Kazuhiro Koyanagawa; Yuta Kobayashi; Tadao Aikawa; Atsuhito Takeda; Hideaki Shiraishi; Satonori Tsuneta; Noriko Oyama-Manabe; Hiroyuki Iwano; Toshiyuki Nagai; Toshihisa Anzai
  Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 20, 3, 320, 324, 2021年09月01日, ［査読有り］, ［国内誌］
  英語, 研究論文（学術雑誌）, To assess myocardial fibrosis associated with muscular dystrophy, T1-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dystrophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.
• Successful transvenous embbolization for type II uterine arteriovenous malformation: A case report.
  Ryo Morita; Daisuke Abo; Naoya Kinota; Takeshi Soyama; Bunya Takahashi; Yuki Yoshino; Satonori Tsuneta; Kohsuke Kudo
  Radiology case reports, 16, 8, 2007, 2011, 2021年08月, ［査読有り］, ［国際誌］
  英語, A 40-year-old female (gravida 3 para 1) presented with menstrual, urinary, and anal pain. Computed tomography revealed type II acquired uterine arteriovenous malformation, a common dilated venous sac with bilateral uterine arteries, and multiple branches of iliac arteries draining to the bilateral ovarian veins. Venous sac transvenous embolization via the left ovarian vein of dominant outflow was planned, since complete arteriovenous malformation occlusion was difficult with super-selective transarterial embolization of multiple feeders. Therefore, transarterial embolization of the minor feeder was performed before completing transvenous embolization using coils and 50% glue under left iliac artery flow control. Immediately thereafter, angiography confirmed the complete disappearance of the uterine arteriovenous malformation, and all pain symptoms remitted. In conclusion, transvenous embolization combined with adjunctive transarterial embolization can be an effective and radical treatment for type II uterine arteriovenous malformations.
• The assessment of left heart disease in patients with systemic sclerosis and pulmonary hypertension
  Satonori Tsuneta
  CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 39, 4, 103, 110, 2021年07月28日, ［査読有り］
  研究論文（学術雑誌）
• Blood flow dynamics with four-dimensional flow cardiovascular magnetic resonance in patients with aortic stenosis before and after transcatheter aortic valve replacement.
  Hirokazu Komoriyama; Kiwamu Kamiya; Toshiyuki Nagai; Noriko Oyama-Manabe; Satonori Tsuneta; Yuta Kobayashi; Yoshiya Kato; Miwa Sarashina; Kazunori Omote; Takao Konishi; Takuma Sato; Shingo Tsujinaga; Hiroyuki Iwano; Yasushige Shingu; Satoru Wakasa; Toshihisa Anzai
  Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 23, 1, 81, 81, 2021年06月28日, ［査読有り］, ［国際誌］
  英語, 研究論文（学術雑誌）, BACKGROUND: Pre- and post-procedural hemodynamic changes which could affect adverse outcomes in aortic stenosis (AS) patients who undergo transcatheter aortic valve replacement (TAVR) have not been well investigated. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) enables accurate analysis of blood flow dynamics such as flow velocity, flow pattern, wall shear stress (WSS), and energy loss (EL). We sought to examine the changes in blood flow dynamics of patients with severe AS who underwent TAVR. METHODS: We examined 32 consecutive severe AS patients who underwent TAVR between May 2018 and June 2019 (17 men, 82 ± 5 years, median left ventricular ejection fraction 61%, 6 self-expanding valve), after excluding those without CMR because of a contraindication or inadequate imaging from the analyses. We analyzed blood flow patterns, WSS and EL in the ascending aorta (AAo), and those changes before and after TAVR using 4D flow CMR. RESULTS: After TAVR, semi-quantified helical flow in the AAo was significantly decreased (1.4 ± 0.6 vs. 1.9 ± 0.8, P = 0.002), whereas vortical flow and eccentricity showed no significant changes. WSS along the ascending aortic circumference was significantly decreased in the left (P = 0.038) and left anterior (P = 0.033) wall at the basal level, right posterior (P = 0.011) and left (P = 0.010) wall at the middle level, and right (P = 0.012), left posterior (P = 0.019) and left anterior (P = 0.028) wall at the upper level. EL in the AAo was significantly decreased (15.6 [10.8-25.1 vs. 25.8 [18.6-36.2]] mW, P = 0.012). Furthermore, a significant negative correlation was observed between EL and effective orifice area index after TAVR (r = - 0.38, P = 0.034). CONCLUSIONS: In severe AS patients undergoing TAVR, 4D flow CMR demonstrates that TAVR improves blood flow dynamics, especially when a larger effective orifice area index is obtained.
• Clinical Applications of 4D Flow MR Imaging in Aortic Valvular and Congenital Heart Disease.
  Noriko Oyama-Manabe; Tadao Aikawa; Satonori Tsuneta; Osamu Manabe
  Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 21, 2, 319, 326, 2021年06月25日, ［査読有り］, ［国内誌］
  英語, 研究論文（学術雑誌）, 4D flow MRI allows time-resolved 3D velocity-encoded phase-contrast imaging for 3D visualization and quantification of aortic and intracardiac flow. Radiologists should be familiar with the principles of 4D flow MRI and methods for evaluating blood flow qualitatively and quantitatively. The most substantial benefits of 4D flow MRI are that it enables the simultaneous comprehensive assessment of different vessels, and that retrospective analysis can be achieved in all vessels in any direction in the field of view, which is especially beneficial for patients with complicated congenital heart disease (CHD). For aortic valvular diseases, new parameters such as wall shear stress and energy loss may provide new prognostic values for 4D flow MRI. In this review, we introduce the clinical applications of 4D flow MRI for the visualization of blood flow and quantification of hemodynamic metrics in the setting of aortic valvular disease and CHD, including intracardiac shunt and coronary artery anomaly.
• 4-Dimensional Flow Cardiovascular Magnetic Resonance Imaging of Changes in Blood Flow Dynamics After Surgery for Discrete Subaortic Stenosis.
  Hirokazu Komoriyama; Kiwamu Kamiya; Yuta Kobayashi; Satonori Tsuneta; Takao Konishi; Takuma Sato; Hiroyuki Iwano; Toshiyuki Nagai; Satoru Wakasa; Kohsuke Kudo; Toshihisa Anzai
  Circulation journal : official journal of the Japanese Circulation Society, 85, 6, 954, 954, 2021年05月25日, ［査読有り］, ［国内誌］
  英語, 研究論文（学術雑誌）
• Texture analysis of delayed contrast-enhanced computed tomography to diagnose cardiac sarcoidosis.
  Satonori Tsuneta; Noriko Oyama-Manabe; Kenji Hirata; Taisuke Harada; Tadao Aikawa; Osamu Manabe; Hiroshi Ohira; Kazuhiro Koyanagawa; Masanao Naya; Kohsuke Kudo
  Japanese journal of radiology, 39, 5, 442, 450, 2021年05月, ［査読有り］, ［筆頭著者］, ［国内誌］
  英語, 研究論文（学術雑誌）, PURPOSE: To investigate the diagnostic value of texture analysis to differentiate cardiac sarcoidosis (CS) from other non-ischemic cardiomyopathies (non-CS). MATERIALS AND METHODS: Twenty CS patients and 15 non-CS patients who had undergone myocardial CT delayed enhancement (CTDE) were included. A total of 36 texture features were calculated according to the CT attenuation of CTDE. We investigated the diagnostic value to differentiate CS from non-CS. We also assessed the intra- and inter-rater reproducibility for each feature and inter-observer agreement for visual assessment. RESULTS: Seven extracted features had significantly higher run length non-uniformity (RLNU) values (5.4 × 102 ± 6.2 × 102 vs. 11.2 × 102 ± 4.9 × 102, p = 0.037) and significantly lower low gray-level zone emphasis (LGZE) values (7.1 × 10-3 ± 8.6 × 10-3 vs. 18.1 × 10-3 ± 16.9 × 10-3, p = 0.017) in CS than in non-CS. Intra- and inter-rater reproducibility of RLNU and LGZE were excellent (ICCs > 0.8), while inter-observer agreement of visual assessment was poor (kappa = 0.19). The accuracies of texture analysis were 69% with RLNU and 71% with LGZE, which were better than that of visual assessment. CONCLUSION: Texture analysis of CTDE could differentiate CS from non-CS with high reproducibility.
• The Role of Multimodality Imaging in Cardiac Sarcoidosis
  Satonori Tsuneta
  KOREAN CIRCULATION JOURNAL, 51, 7, 561, 561, 2021年, ［査読有り］
  研究論文（学術雑誌）
• RadioGraphics Update: IgG4-related Cardiovascular Disease from the Aorta to the Coronary Arteries
  Satonori Tsuneta
  RADIOGRAPHICS, 40, 7, E29, E32, 2020年11月, ［査読有り］
  研究論文（学術雑誌）
• Visualization of Quantitative Flow Reduction with 4D-flow Magnetic Resonance Imaging in a Patient with Pelvic Arteriovenous Malformation After Transcatheter Arterial Embolization
  Satonori Tsuneta
  CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 43, 10, 1557, 1560, 2020年10月, ［査読有り］, ［筆頭著者］
  研究論文（学術雑誌）
• Usefulness of Liver Magnetic Resonance Elastography for Estimating Right-Atrial Pressure in Heart Failure Patients.
  Yoshiya Kato; Toshiyuki Nagai; Noriko Oyama-Manabe; Satonori Tsuneta; Michikazu Nakai; Yuta Kobayashi; Hirokazu Komoriyama; Kazunori Omote; Shingo Tsujinaga; Takuma Sato; Takao Konishi; Kiwamu Kamiya; Hiroyuki Iwano; Toshihisa Anzai
  JACC. Cardiovascular imaging, 13, 9, 2050, 2052, 2020年09月, ［査読有り］, ［国際誌］
  英語
• Improvement of image quality on low-dose dynamic myocardial perfusion computed tomography with a novel 4-dimensional similarity filter
  Satonori Tsuneta
  MEDICINE, 99, 26, e20804, e20804, 2020年06月26日, ［査読有り］, ［筆頭著者］
  英語, 研究論文（学術雑誌）
• Four-dimensional flow magnetic resonance imaging visualizes significant changes in flow pattern and wall shear stress in the ascending aorta after transcatheter aortic valve implantation in a patient with severe aortic stenosis
  Satonori Tsuneta
  EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2020年, ［査読有り］
  研究論文（学術雑誌）
• The detection of retrograde flow from the left anterior descending artery into the main pulmonary artery by 4D-flow cardiac magnetic resonance in a patient with Bland-White-Garland syndrome
  Satonori Tsuneta; Noriko Oyama-Manabe; Atsuhito Takeda; Kota Taniguchi; Osamu Manabe
  European Heart Journal - Cardiovascular Imaging, 20, 4, 488, 488, Oxford University Press (OUP), 2019年04月01日, ［査読有り］, ［筆頭著者］
  研究論文（学術雑誌）

• 前立腺T2WIにおける深層学習再構成の画質改善と撮像時間短縮
  西岡 典子; 藤間 憲幸; 常田 慧徳; 坂本 圭太; 濱口 裕行; 松本 隆児; 工藤 與亮, 日本医学放射線学会秋季臨床大会抄録集, 61回, S449, S449, 2025年09月
  (公社)日本医学放射線学会, 日本語
• 肺癌の術前検査で偶発的に発見されたMinute pulmonary meningothelial-like nodulesの1例
  小林 圭太; 吉川 仁人; 常田 慧徳; 中川 純一; 木村 理奈; 西岡 典子; 坂本 圭太; 加藤 扶美; 氏家 秀樹; 岡崎 ななせ; 松野 吉宏; 工藤 與亮, Japanese Journal of Radiology, 43, Suppl., 4, 4, 2025年02月
  (公社)日本医学放射線学会, 日本語
• 前立腺DWIへのモデルベース深層学習下画像再構成の応用
  西岡 典子; 藤間 憲幸; 常田 慧徳; 吉川 仁人; 木村 理奈; 坂本 圭太; 加藤 扶美; 松本 隆児; 権 池勲; 米山 正己; 工藤 與亮, 日本医学放射線学会秋季臨床大会抄録集, 60回, S417, S417, 2024年09月
  (公社)日本医学放射線学会, 日本語
• サルコイドーシス患者におけるMRI心筋ストレイン、遅延造影、及びFDG集積の相関性の検討
  高橋 慶子; 真鍋 治; 相川 忠夫; 常田 慧徳; 真鍋 徳子, 日本心臓核医学会ニュースレター, 26, 2, 74, 74, 2024年05月
  日本心臓核医学会, 日本語
• 低血糖発作を合併した胸膜孤立性線維性腫瘍の1例
  村本 朋之; 中川 純一; 常田 慧徳; 高橋 文也; 木村 理奈; 西岡 典子; 坂本 圭太; 加藤 扶美; 氏家 秀樹; 加藤 達哉; 大藤 悠里; 亀田 啓; 中村 昭伸; 若林 健人; 松野 吉宏; 工藤 與亮, Japanese Journal of Radiology, 42, Suppl., 4, 4, 2024年02月
  (公社)日本医学放射線学会, 日本語
• 低血糖発作を合併した胸膜孤立性線維性腫瘍の1例
  村本 朋之; 中川 純一; 常田 慧徳; 高橋 文也; 木村 理奈; 西岡 典子; 坂本 圭太; 加藤 扶美; 氏家 秀樹; 加藤 達哉; 大藤 悠里; 亀田 啓; 中村 昭伸; 若林 健人; 松野 吉宏; 工藤 與亮, Japanese Journal of Radiology, 42, Suppl., 4, 4, 2024年02月
  (公社)日本医学放射線学会, 日本語
• 深層学習を用いた心尖部四腔像からの右室駆出率の推定
  村山 迪史; 加賀 早苗; 向井 葵; 永井 優衣; 杉森 博行; 吉村 高明; 島 秀起; 常田 慧徳; 西野 久雄; 中村 順一; 佐藤 隆博; 辻野 一三, 超音波検査技術抄録集, 49, S172, S172, 2024年
  一般社団法人 日本超音波検査学会, 日本語
• Prognostic Value of Spleen Stiffness Assessed by Magnetic Resonance Elastography in Patients with Heart Failure
  Satonori Tsuneta, CIRCULATION, 2024年
• FDG accumulation in the nasal mucosa with normal CT finding in intravascular B-cell lymphoma compared with diffuse large B-cell lymphoma; a retrospective multicenter study
  Satonori Tsuneta, JOURNAL OF NUCLEAR MEDICINE, 2024年
• Differences on Periprocedural Blood Flow Dynamics between Self- and Balloon-expandable Valves in Patients with Small Aortic Annulus Undergoing Transcatheter Aortic Replacement
  Satonori Tsuneta, CIRCULATION, 2024年
• 心臓サルコイドーシス患者におけるガドリニウム遅延造影心臓MRIとFDG-PETを用いた複合的画像評価の予後的意義
  數井 翔; 竹中 秀; 永井 利幸; 常田 慧徳; 加藤 喜哉; 小森山 弘和; 小林 雄太; 高橋 昌寛; 神谷 究; 天満 太郎; 佐藤 琢真; 多田 篤司; 安井 悠太郎; 中井 陸運; 佐藤 隆博; 辻野 一三; 工藤 與亮; 今野 哲; 安斉 俊久, 日本サルコイドーシス/肉芽腫性疾患学会雑誌, 43, サプリメント号, 65, 65, 2023年10月
  日本サルコイドーシス, 日本語
• 心臓サルコイドーシス患者におけるガドリニウム遅延造影心臓MRIとFDG-PETを用いた複合的画像評価の予後的意義
  數井 翔; 竹中 秀; 永井 利幸; 常田 慧徳; 加藤 喜哉; 小森山 弘和; 小林 雄太; 高橋 昌寛; 神谷 究; 天満 太郎; 佐藤 琢真; 多田 篤司; 安井 悠太郎; 中井 陸運; 佐藤 隆博; 辻野 一三; 工藤 與亮; 今野 哲; 安斉 俊久, 日本サルコイドーシス/肉芽腫性疾患学会雑誌, 43, サプリメント号, 65, 65, 2023年10月
  日本サルコイドーシス, 日本語
• 4D-flowMRIを使用した奇静脈瘤術前の内部血流評価—Presurgical assessment of flow variability in an azygos vein aneurysm using 4D-flow MRI
  幾島 拓也; 氏家 秀樹; 常田 慧徳; 千葉 龍平; 田畑 佑希子; 藤原 晶; 樋田 泰浩; 加賀 基知三; 若狭 哲; 加藤 達哉, 北海道外科雑誌 = The Hokkaido journal of surgery / 北海道外科雑誌編集委員会 編, 68, 1, 52, 54, 2023年06月
  [札幌] : 北海道外科学会, 日本語
• 4D-flow MRIを用いたportosystemic shunt閉塞前後の門脈血流評価
  加藤 大祐; 阿保 大介; 木野田 直也; 常田 慧徳; 石坂 欣也; 森田 亮; 高橋 文也; 藤井 宝顕; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 38, Suppl., 237, 237, 2023年04月
  (一社)日本インターベンショナルラジオロジー学会, 日本語
• 4D-flow MRIを用いたportosystemic shunt閉塞前後の門脈血流評価
  加藤 大祐; 阿保 大介; 木野田 直也; 常田 慧徳; 石坂 欣也; 森田 亮; 高橋 文也; 藤井 宝顕; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 38, Suppl., 237, 237, 2023年04月
  (一社)日本インターベンショナルラジオロジー学会, 日本語
• PVOD/PCHに対してイマチニブを使用した5症例の検討
  中村順一; 辻野一三; 辻野一三; 島秀起; 杉本絢子; 佐藤隆博; 佐藤隆博; 大平洋; 鈴木雅; 常田慧徳; 久田諒; 加藤将; 今野哲; 今野哲, 日本肺高血圧・肺循環学会学術集会抄録集(Web), 8th, 2023年
• Prognostic Value of Combined Assessment of Cardiac Magnetic Resonance and Fluorodeoxyglucose Positron Emission Tomography in Patients With Cardiac Sarcoidosis
  Satonori Tsuneta, CIRCULATION, 2023年
• 胎児期にMRIを2回撮像し経時変化を確認できた両側multicystic dysplastic kidneyによるPotter sequencesの1例
  加藤扶美; 常田慧徳; 池辺洋平; 木村理奈; 齊藤良玄; 馬詰武; 古瀬優太; 大塚拓也; 谷口浩二; 中川純一; 吉川仁人; 西岡典子; 坂本圭太; 原田太以佑; 工藤與亮, Abstracts. Annual Symposium. Japanese Society for the Advancement of Women’s Imaging (CD-ROM), 24th, 2023年
• AIによる肝臓セグメンテーションの性能評価と肝臓体積の経時的変化
  木村 理奈; 平田 健司; 常田 慧徳; 竹中 淳規; 渡邊 史郎; 阿保 大介; 工藤 與亮, 日本医学放射線学会秋季臨床大会抄録集, 59回, S403, S403, 2022年09月
  (公社)日本医学放射線学会, 日本語
• 乳房専用超音波CTによる乳癌検出能の検討
  加藤 扶美; 佐藤 恵美; 西田 睦; 竹下 卓志; 押野 智博; 常田 慧徳; 守谷 結美; 上石 崇史; 桑山 真紀; 高橋 將人; 工藤 與亮, 日本乳癌学会総会プログラム抄録集, 30回, PO6, 6, 2022年06月
  (一社)日本乳癌学会, 日本語
• 前毛細管性肺高血圧症における心筋遅延造影像と左室収縮障害との関連
  新川 未緒; 加賀 早苗; 岩野 弘幸; 千葉 泰之; 宮本 知佳; 岡田 一範; 村山 迪史; 中鉢 雅大; 常田 慧徳; 辻野 一三, 超音波医学, 49, Suppl., S706, S706, 2022年04月
  (公社)日本超音波医学会, 日本語
• 北海道大学病院におけるPVOD/PCH11症例の検討
  中村順一; 辻野一三; 島秀起; 中谷資隆; 杉本絢子; 佐藤隆博; 渡部拓; 鈴木雅; 大平洋; 常田慧徳; 今野哲, 日本肺高血圧・肺循環学会学術集会抄録集(Web), 7th, 2022年
• ドプラ心エコー法による肺動脈弁逆流重症度の過大評価の要因に関する検討
  本居昂; 岩野弘幸; 岩野弘幸; 常田慧徳; 村山迪史; 加賀早苗; 青柳裕之; 玉置陽生; 石坂傑; 千葉泰之; 辻永真吾; 種村明日香; 横山しのぶ; 中鉢雅大; 西野久雄; 岡田一範; 武田充人; 安斉俊久, 日本成人先天性心疾患学会雑誌(Web), 11, 1, 2022年
• 前毛細管性肺高血圧症における心筋遅延造影像と左室収縮障害との関連
  新川未緒; 加賀早苗; 岩野弘幸; 千葉泰之; 宮本知佳; 岡田一範; 村山迪史; 村山迪史; 中鉢雅大; 常田慧徳; 辻野一三, 超音波医学 Supplement, 49, 2022年
• 小児画像診断のコツ II.読影のコツ(マネージメントのコツ含む)4.心大血管におけるコツ 先天性心疾患
  常田慧徳; 加藤伸康; 武田充人, 小児科診療, 85, 2022年
• 乳房専用超音波CTにおける高精細音速像の有用性(第2報)
  加藤 扶美; 佐藤 恵美; 西田 睦; 山下 啓子; 竹下 卓志; 萩尾 加奈子; 押野 智博; 亀田 浩之; 常田 慧徳; 堀江 達則; 寺田 崇秀; 坪田 悠史; 川畑 健一; 田中 宏樹; 工藤 與亮, 日本乳癌学会総会プログラム抄録集, 29回, 72, 72, 2021年07月
  (一社)日本乳癌学会, 日本語
• 肺動静脈奇形に対する4D flow MRIによる血流評価の実行可能性に関する検討
  阿保 大介; 常田 慧徳; 曽山 武士; 森田 亮; 吉野 裕紀; 高橋 文也; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 36, Suppl., 167, 167, 2021年04月
  (一社)日本インターベンショナルラジオロジー学会, 日本語
• 血管モデルによる術前シミュレーションを併用したpreloading coil in plug法での腎AVF塞栓術の1例
  森田 亮; 阿保 大介; 曽山 武士; 高橋 文也; 吉野 裕紀; 山崎 康之; 常田 慧徳; 今井 哲秋; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 36, Suppl., 241, 241, 2021年04月
  (一社)日本インターベンショナルラジオロジー学会, 日本語
• Precision Medicine時代のCardiac Imaging 2021 技術革新が切り開く循環器画像診断の未来 後編 V MRI:循環器領域における臨床の最前線と技術の到達点 1.MRIの技術革新が広げる循環器画像診断の可能性 5)心臓領域における新しいルーチンシーケンスの臨床的有用性
  常田慧徳; 真鍋徳子, Innervision, 36, 5, 2021年
• マルチモダリティが診断に有用であった肺動脈内膜肉腫の1例
  朴貞恩; 常田慧徳; 真鍋徳子; 真鍋治; 加藤扶美; 工藤與亮; 福井秀章; 三橋智子; 松野吉宏, Japanese Journal of Radiology, 39, Supplement, 2021年
• IgG4関連肺病変を背景に生じた非角化型扁平上皮癌の一例
  大塚拓也; 伊藤祥太郎; 松本宗大; 氏家秀樹; 常田慧徳; 平田健司; 朝比奈肇; 加賀基知三; 松野吉宏, 日本病理学会会誌, 110, 1, 2021年
• 心臓サルコイドーシス患者における血清可溶性インターロイキン2レセプター高値は長期予後と関連する
  小林雄太; 永井利幸; 平田健司; 常田慧徳; 加藤喜哉; 小森山弘和; 神谷究; 小西崇夫; 佐藤琢真; 表和徳; 工藤與亮; 今野哲; 安斉俊久, 日本サルコイドーシス/肉芽腫性疾患学会雑誌, 41, 2021年
• MRIのT1mappingによる心筋細胞外容積分画は筋ジストロフィーによるびまん性心筋障害の検出に有用である
  相川忠夫; 小梁川和宏; 小林雄太; 武田充人; 白石秀明; 常田慧徳; 岩野弘幸; 永井利幸; 安斉俊久; 真鍋徳子, 日本心血管画像動態学会プログラム・抄録集, 31st (CD-ROM), 2021年
• 目でみる肺高血圧症 右心評価におけるMRI
  常田 慧徳; 佐藤 隆博; 大平 洋; 辻野 一三, Pulmonary Hypertension Update, 6, 2, 76, 80, 2020年11月
  (株)メディカルレビュー社, 日本語
• 乳房専用超音波CTの初期使用経験 高精細音速像の有用性
  加藤 扶美; 山下 啓子; 佐藤 恵美; 西田 睦; 竹下 卓志; 萩尾 加奈子; 押野 智博; 亀田 浩之; 常田 慧徳; 堀江 達則; 寺田 崇秀; 坪田 悠史; 川畑 健一; 工藤 與亮, 日本乳癌学会総会プログラム抄録集, 28回, 144, 144, 2020年10月
  (一社)日本乳癌学会, 日本語
• 乳房専用超音波CTの初期使用経験 高精細音速像の有用性
  加藤 扶美; 山下 啓子; 佐藤 恵美; 西田 睦; 竹下 卓志; 萩尾 加奈子; 押野 智博; 亀田 浩之; 常田 慧徳; 堀江 達則; 寺田 崇秀; 坪田 悠史; 川畑 健一; 工藤 與亮, 日本乳癌学会総会プログラム抄録集, 28回, 144, 144, 2020年10月
  (一社)日本乳癌学会, 日本語
• 巨大骨盤AVMに対する塞栓術の治療効果を4D-flow MRIにより定量的に評価できた一例(Quantitative evaluation of a giant pelvic arteriovenous malformation by 4D-flow MRI: a case report)
  阿保 大介; 常田 慧徳; 真鍋 徳子; 曽山 武士; 森田 亮; 吉野 裕紀; 木野田 直也; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 35, Suppl., 179, 179, 2020年08月
  (一社)日本インターベンショナルラジオロジー学会, 英語
• 子宮動静脈奇形に対し動脈塞栓術併用経静脈的塞栓術を施行した1例
  森田 亮; 阿保 大介; 木野田 直也; 曽山 武士; 吉野 裕紀; 常田 慧徳; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 35, Suppl., 217, 217, 2020年08月
  (一社)日本インターベンショナルラジオロジー学会, 日本語
• 巨大骨盤AVMに対する塞栓術の治療効果を4D-flow MRIにより定量的に評価できた一例(Quantitative evaluation of a giant pelvic arteriovenous malformation by 4D-flow MRI: a case report)
  阿保 大介; 常田 慧徳; 真鍋 徳子; 曽山 武士; 森田 亮; 吉野 裕紀; 木野田 直也; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 35, Suppl., 179, 179, 2020年08月
  (一社)日本インターベンショナルラジオロジー学会, 英語
• 子宮動静脈奇形に対し動脈塞栓術併用経静脈的塞栓術を施行した1例
  森田 亮; 阿保 大介; 木野田 直也; 曽山 武士; 吉野 裕紀; 常田 慧徳; 工藤 與亮, 日本インターベンショナルラジオロジー学会雑誌, 35, Suppl., 217, 217, 2020年08月
  (一社)日本インターベンショナルラジオロジー学会, 日本語
• VISUALIZATION OF PERIPROCEDUAL BLOOD FLOW DYNAMICS WITH FOUR-DIMENSIONAL FLOW MAGNETIC RESONANCE IMAGING IN PATIENTS WITH SEVERE AORTIC STENOSIS UNDERGOING TRANSCATHETER AORTIC VALVE REPLACEMENT
  Hirokazu Komoriyama; Kiwamu Kamiya; Toshiyuki Nagai; Noriko Oyama-Manabe; Satonori Tsuneta; Yuta Kobayashi; Yoshiya Kato; Kazunori Omote; Takao Konishi; Takuma Sato; Shingo Tsujinaga; Hiroyuki Iwano; Yasushige Shingu; Satoru Wakasa; Toshihisa Anzai, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 75, 11, 1639, 1639, 2020年03月
  英語, 研究発表ペーパー・要旨（国際会議）
• The role of right ventricular late gadolinium enhancement scoring by cardiac magnetic resonance imaging in cardiac sarcoidosis
  Satonori Tsuneta, EUROPEAN HEART JOURNAL, 2020年
• 心臓イメージング2020 令和時代の循環器イメージングにおける新しい潮流
  真鍋徳子; 常田慧徳; 真鍋治, 映像情報Medical, 52, 3, 2020年
• 車輻状の血管構築を呈した転移性肝神経内分泌腫瘍の1例
  板垣有紀; 板垣有紀; 西田睦; 西田睦; 常田慧徳; 佐藤恵美; 佐藤恵美; 工藤悠輔; 工藤悠輔; 表原里実; 表原里実; 渋谷斉; 岡田宏美; 松野吉宏; 蒲池浩文, 超音波医学, 47, 2, 2020年
• Value based medicine時代の心血管画像診断 Value based medicine時代の心臓CT
  真鍋徳子; 常田慧徳, 画像診断, 40, 12, 2020年
• Dynamic心筋CT perfusionに対するfour-dimensional similarity filterの画質改善効果の検討
  常田慧徳; 常田慧徳; 真鍋徳子; 亀田浩之; 原田太以佑; 加藤扶美; 工藤與亮, 日本心血管画像動態学会プログラム・抄録集, 30th, 2020年
• 画像診断と病理 肺動脈内膜肉腫
  山崎康之; 常田慧徳; 朴貞恩; 原田太以佑; 工藤與亮; 大岡智学; 福井秀章; 大塚拓也, 画像診断, 40, 10, 2020年
• Increased Liver Stiffness Assessed by Magnetic Resonance Elastography Predicts Elevated Right Atrial Pressure in Patients with Heart Failure(和訳中)
  加藤 喜哉; 永井 利幸; 小森山 弘和; 表 和徳; 相川 忠夫; 神谷 究; 常田 慧徳; 真鍋(大山) 徳子; 安斉 俊久, 日本循環器学会学術集会抄録集, 83回, PJ096, 6, 2019年03月
  (一社)日本循環器学会, 英語
• 心不全患者におけるMRエラストグラフィで評価した肝硬度の増加は右心房圧の上昇を予測する(Increased Liver Stiffness Assessed by Magnetic Resonance Elastography Predicts Elevated Right Atrial Pressure in Patients with Heart Failure)
  加藤 喜哉; 永井 利幸; 小森山 弘和; 表 和徳; 相川 忠夫; 神谷 究; 常田 慧徳; 真鍋 徳子[大山]; 安斉 俊久, 日本循環器学会学術集会抄録集, 83回, PJ096, 6, 2019年03月
  (一社)日本循環器学会, 英語
• ¹⁷O標識水の第1相臨床試験:安全性および脳血流MRIの実現可能性に関する検討
  原田太以佑; 工藤與亮; 亀田浩之; 佐藤良太; 白猪亨; 尾藤良孝; 藤間憲幸; 常田慧徳; 野川敏史; 前田憲一郎; 林宏至; 佐々木真理, 日本磁気共鳴医学会雑誌, 39, 2, 2019年
• 原発性子宮頸部印環細胞癌の1例
  常田慧徳; 加藤扶美; 野崎綾子; 大塚拓也; 三橋智子; 奥聡; 井平圭; 加藤達矢; 渡利英道; 真鍋徳子; 工藤與亮, Abstracts. Annual Symposium. Japanese Society for the Advancement of Women’s Imaging, 20th (CD-ROM), 2019年
• 大喀血で発見された気管支動脈蔓状血管腫の2例
  塩野谷洋輔; 橋本みどり; 小森崇史; 高橋晴香; 呉賢一; 道免寛充; 常田慧徳; 森田亮; 西山薫, 気管支学, 41, 2019年
• 多彩な造影パターンが混在していた肝細胆管細胞癌の1例
  常田慧徳; 藪崎哲史; 加藤扶美; 菊池穏香; 坂本圭太; 三村理恵; 真鍋徳子; 工藤與亮; 畑中佳奈子, Japanese Journal of Radiology, 36, Supplement, 2018年
• 長期間経過を追えたCerebral Amyloid Angiopathyの1例
  常田慧徳; 原田太以佑; 吉田篤司; 清水幸衣; 藤間憲幸; 工藤與亮; 西村洋昭; 佐々木秀直; THA Khin Khin; 白土博樹, Japanese Journal of Radiology, 36, Supplement, 2018年
• 成熟嚢胞性奇形腫に合併した神経内分泌性格を伴う非典型的な粘液性腫瘍の一例
  常田慧徳; 加藤扶美; 三田村卓; 大塚拓也; 高桑恵美; 中智昭; 中智昭; 松野吉宏; 奥聡; 朝野拓史; 野崎綾子; 加藤達也; 渡利英道; 真鍋徳子; 工藤與亮, Abstracts. Annual Symposium. Japanese Society for the Advancement of Women’s Imaging, 19th, 2018年
• Pulmonary tumor thrombotic microangiopathy(PTTM)の1例-生前~死後CT,そして解剖との対比-
  吉野裕紀; 菊池穏香; 菊池穏香; 常田慧徳; 加藤扶美; 加藤扶美; 工藤與亮; 工藤與亮; 仲川心平; 田中敏; 白土博樹; 白土博樹, 日本医学放射線学会秋季臨床大会抄録集, 54th, 2018年
• MRIによる子宮体癌と子宮癌肉腫の鑑別に関する検討
  常田慧徳; 常田慧徳; 加藤扶美; 朝野拓史; 野崎綾子; 井平圭; 三田村卓; 金野陽輔; 加藤達矢; 渡利英道; 飯嶋由紀; 西岡井子; 真鍋徳子; 工藤與亮, 日本医学放射線学会秋季臨床大会抄録集, 53rd, 2017年
• くも膜下出血の原因推定(内因性/外因性)に苦慮した一例
  竹内肇; 竹内肇; 舘岡一芳; 八巻多; 徳光直樹; 常田慧徳; 常田慧徳; 藤田智; 岡田基, 名寄市立病院医誌, 23, 1, 2015年

• 遺伝子治療時代を見据えたDMD心臓病変のMRI診断
  常田慧徳
  関西エレビジス適正使用セミナー, 2026年03月25日, 日本語, 公開講演，セミナー，チュートリアル，講習，講義等
  2026年03月25日 - 2026年03月25日, ［招待講演］
• 遺伝子治療時代を見据えたDMD心臓病変のMRI診断
  常田慧徳
  中四国遺伝子治療安全性セミナー, 2026年02月18日, 日本語, 公開講演，セミナー，チュートリアル，講習，講義等
  2026年02月18日 - 2026年02月18日, ［招待講演］
• Cardiac vascular imaging: non-contrast MRA
  Satonori Tsuneta
  Philips Cardiac Imaging Symposium in Dubai, 2026年02月13日, 英語, 口頭発表（招待・特別）
  2026年02月13日 - 2026年02月13日, ［招待講演］
• 心筋炎に対する心臓MRIの有用性
  常田慧徳
  中外eセミナー on DMD, 2026年01月26日, 日本語, 公開講演，セミナー，チュートリアル，講習，講義等
  2026年01月26日 - 2026年01月26日, ［招待講演］
• 心臓MRIブラッシュアップ ― 診断だけで終わらせない遅延造影評価 ―
  常田慧徳
  第39回JCRミッドウィンターセミナー, 2026年01月10日, 日本語, 公開講演，セミナー，チュートリアル，講習，講義等
  2026年01月10日 - 2026年01月10日, ［招待講演］
• 4D flow MRI の苦手克服 - 基礎から応用まで -
  常田慧徳
  第 61 回日本医学放射線学会秋季臨床大会, 2025年10月17日, 日本語, 口頭発表（招待・特別）
  2025年10月17日 - 2025年10月19日, ［招待講演］
• 心大血管MRIを変える、最新技術の力 ーよりスマートに、よりシンプルにー
  常田慧徳
  第19回Philips画像診断webセミナー, 2025年10月09日, 日本語, 口頭発表（招待・特別）
  2025年10月09日 - 2025年10月09日, ［招待講演］
• 二次動き補償心臓拡散強調像に対するガドリニウム造影剤の影響
  常田慧徳; 青野聡; 権池勲; 米山正己; 上原拓樹; 青池拓哉; 竹中秀; 児矢野英典; 藤間憲幸; 永井利幸; 安斉俊久; 箕輪和行; 工藤與亮
  第53回日本磁気共鳴医学会大会, 2025年08月29日, 日本語, ポスター発表
  2025年08月29日 - 2025年08月31日
• Gadolinium-based contrast agent and stimulated echo acquisition mode cardiac diffusion-weighted imaging: preliminary results
  Satonori Tsuneta; Satoru Aono; Jihun Kwon; Masami Yoneyama; Hiroki Uehara; Takuya Aoike; Sakae Takenaka; Hidenori Koyano; Noriyuki Fujima; Toshiyuki Nagai; Toshihisa Anzai; Kazuyuki Minowa; Kohsuke Kudo
  2025 ISMRM & ISMRT Annual Meeting & Exhibition, 2025年05月14日, 英語, ポスター発表
  2025年05月10日 - 2025年05月15日, 42241183;40259185
• 心血管MRIの最新技術と臨床応用の要点
  常田慧徳
  第84回日本医学放射線学会総会, 2025年04月11日, 日本語
  2025年04月10日 - 2025年04月13日, ［招待講演］
• ケースから学ぶ心臓画像診断 心サルコイドーシスの読影のポイントと注意点
  常田慧徳
  第100回日本心臓血管放射線研究会, 2025年02月15日, 日本語
  2025年02月15日 - 2025年02月15日, ［招待講演］
• 心筋虚血評価における各モダリティの比較 MRIの長所
  常田慧徳
  第42回北海道心臓核医学研究会, 2025年01月31日
  2025年01月31日 - 2025年01月31日, ［招待講演］
• 13Cのポテンシャル：13Cコイル導入とその実際2 〜放射線科医の視点〜
  常田慧徳
  第1回北海道イメージングセミナー, 2024年11月22日
  2024年11月22日 - 2024年11月22日
• 心血管画像診断を変える、MRI技術の革新と展望
  常田慧徳
  第52回日本磁気共鳴医学会大会, 2024年09月22日, 日本語
  2024年09月20日 - 2024年09月20日, ［招待講演］
• CIEDsにおけるワイドバンドLGEの意義 ワイドバンドLGEの効果：フィリップス
  常田慧徳
  SCMR Japan WG Seminar 2024, 2024年08月03日, 日本語, 公開講演，セミナー，チュートリアル，講習，講義等
  2024年08月03日 - 2024年08月03日, ［招待講演］
• 心臓シネ画像の定量的容積評価に対するSmartSpeed AIの効果
  常田慧徳; 青野聡; 木村理奈; 権池勲; 藤間憲幸; 石坂欣也; 西岡典子; 米山正己; 加藤扶美; 箕輪和行; 工藤與亮
  第98回日本心臓血管放射線研究会, 2024年02月09日
  2024年02月09日 - 2024年02月09日
• 自由自在なSmartSpeedが拓く、心臓MRIの新たな可能性
  常田慧徳
  第16回Philips画像診断webセミナー, 2023年10月12日, 日本語, 公開講演，セミナー，チュートリアル，講習，講義等
  2023年10月12日 - 2023年10月12日, ［招待講演］
• 上行大動脈と主肺動脈のnet flow volumeの一致性の検討
  常田慧徳; 青野聡; 西岡典子; 権池勲; 青池拓哉; 石坂欣也; 米山正己; 藤間憲幸; 加藤扶美; 工藤與亮
  第5回 4D flow MRI研究会, 2023年09月21日, 日本語, 口頭発表（一般）
  2023年09月21日 - 2023年09月21日
• Deep-learning-based super-resolution technique for cine cardiac magnetic resonance
  Satonori Tsuneta; Satoru Aono; Rina Kimura; Jihun Kwon; Takuya Aoike; Masami Yoneyama; Kinya Ishizaka; Noriyuki Fujima; Kohsuke Kudo
  2023 ISMRM & ISMRT Annual Meeting & Exibition, 2023年06月08日, 英語, ポスター発表
  2023年06月03日 - 2023年06月08日
• 体幹部の4D flow MRI -どこまで臨床で使えるのか？-
  常田慧徳
  第91回北海道MRI画像研究会, 2022年06月10日, 日本語
  2022年06月10日 - 2022年06月10日, ［招待講演］
• 虚血性心疾患の基礎：CT
  常田慧徳
  第81回 日本医学放射線学会総会, 2022年04月14日, 英語, 公開講演，セミナー，チュートリアル，講習，講義等
  2022年04月14日 - 2022年04月17日, ［招待講演］
• 4D flow MRIにおけるTurbo-field echo planar imagingとcompressed SENSEとの比較
  常田慧徳; 青野聡; 西岡典子; 青池拓哉; 石坂欣也; 藤間憲幸; 工藤與亮
  第94回日本心臓血管放射線研究会, 2022年01月29日, 日本語, 口頭発表（一般）
  2022年01月29日 - 2022年01月29日
• Texture Analysis of Delayed Contrast-Enhanced Computed Tomography to Differentiate Cardiac Sarcoidosis
  Satonori Tsuneta; Noriko Oyama-Manabe; Taisuke Harada; Osamu Manabe; Kenji Hirata; Kazuhiro Koyanagawa; Masanao Naya; Kohsuke Kudo
  15th Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography, 2020年07月16日, 英語
  2020年07月16日 - 2020年07月19日
• Dynamic 心筋 CT perfusionに対するfour-dimensional similarity filterの画質改善効果の検討
  常田慧徳; 真鍋徳子; 亀田浩之; 原田太以佑; 加藤扶美; 工藤與亮
  第30回 日本心血管画像動態学会, 2020年01月24日, 日本語, 口頭発表（一般）
  2020年01月24日 - 2020年01月24日
• A case series of rare cardiovascular diseases with multimodality imaging
  Satonori Tsuneta
  IAEA Regional Workshop on Clinical Application of Cardiac Multimodality Imaging in Clinical Based Setting Including PET/CT, 2019年10月03日, 英語, シンポジウム・ワークショップパネル（指名）
  2019年09月30日 - 2019年10月04日, ［招待講演］
• 4D flow MRIを用いて定量的に治療効果を評価しえた骨盤内巨大AVMの一例
  常田慧徳; 真鍋徳子; 阿保大介; 工藤與亮
  第1回 4D flow 研究会, 2019年09月19日, 日本語, 口頭発表（一般）
  2019年09月19日 - 2019年09月19日
• 原発性⼦宮頚部印環細胞癌の1例
  常田 慧徳; 加藤 扶美; 野﨑 綾子大塚; 三橋 智子; 奥 聡; 井平 圭; 加藤 達矢; 渡利 英道; 真鍋 徳子; 工藤 與亮
  Japanese Society for the Advancement of Women's Imaging (JSAWI) 第20回シンポジウム, 2019年09月06日, 日本語, ポスター発表
  2019年09月06日 - 2019年09月07日
• Comparison of the effect of 4-dimensional similarity filter and conventional 3-dimensional hybrid iterative reconstruction on image quality of dynamic CT perfusion images for evaluation of myocardial ischemia
  Satonori Tsuneta; Noriko Oyama-Manabe; Tsukasa Sasaki; Hiroyuki Kameda; Taisuke Harada; Fumi Kato; Kohsuke Kudo
  14th Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography, 2019年07月12日, 日本語, 口頭発表（一般）
  2019年07月10日 - 2019年07月14日
• 4D-flow MRIにて左冠動脈の逆行性血流を確認できたBland-White-Garland症候群の一例
  常田慧徳; 真鍋徳子; 加藤扶美; 谷口宏太; 武田充人; 真鍋治; 工藤與亮
  第89回日本心臓血管放射線研究会, 2019年07月06日, 日本語, 口頭発表（一般）
  2019年07月06日 - 2019年07月06日
• Impact of the novel 4-dimensional similarity filter on dynamic myocardial perfusion CT
  Satonori Tsuneta; Noriko Oyama-Manabe; Tsukasa Sasaki; Fumi Kato; Kohsuke Kudo
  The 13th Congress of Asian Society of Cardiovascular lmaging, 2019年03月21日, 英語, 口頭発表（一般）
  2019年03月21日 - 2019年03月23日
• 成熟嚢胞性奇形腫に合併した神経内分泌性格を伴う非典型的な粘液性腫瘍の一例
  常田 慧徳; 加藤 扶美; 三田村 卓; 大塚 拓也; 高桑恵美; 中智昭; 松野 吉宏; 奥 聡; 朝野 拓史; 野﨑 綾子; 加藤 達矢; 渡利 英道; 真鍋 徳子; 工藤 與亮
  Japanese Society for the Advancement of Women's Imaging (JSAWI) 第19回シンポジウム, 2018年08月31日, 日本語, ポスター発表
  2018年08月31日 - 2018年09月01日
• 心筋Perfusion CTにおける新しいノイズ低減法(4-dimensional similarity filter)の画質評価
  常田慧徳; 真鍋徳子; 笹木工; 加藤扶美; 工藤與亮
  第87回日本心臓血管放射線研究会, 2018年07月07日, 日本語
  2018年07月07日 - 2018年07月07日
• MRIによる子宮体癌と子宮癌肉腫の鑑別に関する検討
  常田慧徳; 加藤扶美; 朝野拓史; 野崎綾子; 井平圭; 三田村卓; 金野陽輔; 加藤達矢; 渡利英道; 飯嶋由紀; 西岡井子; 真鍋徳子; 工藤與亮
  第53回日本医学放射線学会秋季臨床大会, 2017年09月08日, 日本語, ポスター発表
  2017年09月08日 - 2017年09月10日
• 術前診断に苦慮した巨大な肝細胆管細胞癌の一例
  常田慧徳; 薮崎哲史; 加藤扶美; 真鍋徳子; 畑中佳奈子; 工藤與亮
  第30回日本腹部放射線学会, 2016年06月25日, 日本語, 口頭発表（一般）
  2016年06月24日 - 2016年06月25日

• 基本医学総論, 2024年, 修士課程, 医学院
• 医学総論, 2024年, 博士後期課程, 医学院
• 臨床医学研究, 2024年, 博士後期課程, 医学院
• コンピューター技法, 2024年, 博士後期課程, 歯学院
• 口腔画像診断学, 2024年, 博士後期課程, 歯学院
• 口腔病態学実習Ⅰ, 2024年, 博士後期課程, 歯学院
• 口腔病態学実習Ⅱ, 2024年, 博士後期課程, 歯学院
• 口腔病態学実習Ⅲ, 2024年, 博士後期課程, 歯学院
• 口腔病態学実習Ⅳ, 2024年, 博士後期課程, 歯学院
• 口腔病態学実習Ⅴ, 2024年, 博士後期課程, 歯学院
• 放射線治療学研究Ⅰ, 2024年, 博士後期課程, 歯学院
• 放射線治療学研究Ⅱ, 2024年, 博士後期課程, 歯学院
• 放射線生物学研究Ⅰ, 2024年, 博士後期課程, 歯学院
• 放射線生物学研究Ⅱ, 2024年, 博士後期課程, 歯学院
• 歯科放射線学, 2024年, 博士後期課程, 歯学院
• 画像診断学研究Ⅰ, 2024年, 博士後期課程, 歯学院
• 画像診断学研究Ⅱ, 2024年, 博士後期課程, 歯学院
• 画像解剖学, 2024年, 学士課程, 医学部
• 歯科放射線学, 2024年, 学士課程, 歯学部
• 歯科放射線学基礎実習, 2024年, 学士課程, 歯学部
• 歯科放射線学臨床実習Ⅰ, 2024年, 学士課程, 歯学部
• 歯科放射線学臨床実習Ⅱ, 2024年, 学士課程, 歯学部
• 内科学, 2024年, 学士課程, 歯学部

• 2023年02月 - 現在
  The International Society for Magnetic Resonance in Medicine
• 2022年09月 - 現在
  日本腹部放射線学会
• 2022年08月 - 現在
  日本磁気共鳴医学会
• 2021年11月 - 現在
  Society for Cardiovascular Magnetic Resonance
• 2019年03月 - 現在
  Society of Cardiovascular Computed Tomography
• 2019年 - 現在
  日本心血管画像動態学会
• 2019年 - 現在
  日本核医学会
• 2016年 - 現在
  日本医学放射線学会

• 造影後拡散テンソル画像を用いた新規心筋バイアビリティ診断指標の開発
  科学研究費助成事業
  2026年04月01日 - 2029年03月31日
  常田 慧徳
  日本学術振興会, 若手研究, 北海道大学, 26K18945
• MRエラストグラフィーを用いた肝うっ血評価による心不全の非侵襲リスク層別法の開発
  科学研究費助成事業
  2023年04月 - 2026年03月
  永井 利幸; 常田 慧徳
  日本学術振興会, 基盤研究(C), 北海道大学, 研究分担者, 23K07174
• 造影後拡散テンソル画像による真の心筋配列の画像化と肥大型心筋症の新規診断法の確立
  科学研究費助成事業 若手研究
  2023年04月 - 2026年03月
  常田 慧徳
  日本学術振興会, 若手研究, 北海道大学, 研究代表者, 23K14910
• 拡散テンソル画像を用いた左室肥大疾患の新たな診断指標の探索に関する検討
  第33回 伊藤記念研究助成金
  2022年10月 - 2023年09月
  常田慧徳
  一般財団法人 北海道心臓協会, 北海道大学病院