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塩原 希 (シオハラ ノゾミ)
| 獣医学研究院 附属動物病院 | 特任助教 |
研究者基本情報
■ 学位■ URL
researchmap URLホームページURL■ ID 各種
研究者番号
- 11041525
研究キーワード研究分野
研究活動情報
■ 受賞- 2025年11月, 日本獣医循環器学会, 優秀学会発表賞
犬の肺高血圧症における無麻酔CT所見と予後の関連性 - 2024年07月, 日本獣医循環器学会, 優秀学会発表賞
大動脈小体腫瘍の心膜転移により収縮性心膜炎を呈した犬の1例 - 2023年12月, 日本獣医循環器学会, 優秀学会発表賞
心疾患の犬におけるShear wave elastography/Dispersion Imagingの有用性の検討 - 2023年09月, 地区学会長賞
犬の腎うっ血の評価におけるShear wave elastographyの有用性の検討
- Evaluation of renal microvascular perfusion in dogs with cardiac disease using Superb Microvascular Imaging
Risa Yasuda; Kensuke Nakamura; Noboru Sasaki; Nozomu Yokoyama; Kazuyoshi Sasaoka; Mei Sugawara-Suda; Sei Kawamoto; Nozomi Shiohara; Yuki Kawakami; Kei Sato; Mitsuyoshi Takiguchi
Journal of Veterinary Internal Medicine, 40, 5, Oxford University Press (OUP), 2026年09月01日
研究論文（学術雑誌）, Abstract
Background
Renal dysfunction in cardiac disease is attributed to both reduced cardiac output and venous congestion; however, relative contributions of these mechanisms are difficult to evaluate clinically.
Hypothesis/Objectives
Renal microvascular perfusion assessed by Superb Microvascular Imaging (SMI) would be associated with indices of cardiac output and venous congestion in dogs with cardiac disease.
Animals
Forty-three client-owned dogs were enrolled: 15 healthy dogs (Control), 21 dogs with cardiac disease but without right-sided heart failure (non-RHF), and 7 dogs with signs of right-sided heart failure (RHF).
Methods
Prospective cross-sectional observational study. SMI images were obtained from renal cortex, and mean SMI signal intensity (SMI-SI) was calculated as an index of renal perfusion. The left ventricular outflow tract velocity-time integral (LVOT-VTI) was used as an index of cardiac output, while caudal vena cava short-to-long axis ratio at minimal inspiratory diameter (CVC SD/LD) was used to indicate venous congestion.
Results
Median SMI-SI was 41.3 (95% CI, 39.1-43.8) in Control, 21.6 (95% CI: 19.4-23.9) in non-RHF, and 18.6 (95% CI, 16.4-21.0) in RHF. Both cardiac disease groups had lower values than Control (P < .001). SMI-SI was negatively correlated with CVC SD/LD (ρ = −0.59, P < .001) and positively correlated with LVOT-VTI (ρ = 0.43, P = .007). In full multivariable analysis, only CVC SD/LD was independently associated with SMI-SI (P = .001).
Conclusions and clinical importance
SMI detects reduced renal microvascular perfusion in dogs with cardiac disease, which is associated with venous congestion rather than cardiac output. - Clinical utility of Shear Wave Speed and Dispersion Slope measured by Shear Wave Elastography for the assessment of hepatic congestion in dogs with cardiac disease
Nozomi Shiohara; Kensuke Nakamura; Masahiro Tamura; Nozomu Yokoyama; Noboru Sasaki; Sei Kawamoto; Mitsuyoshi Takiguchi
Journal of Veterinary Cardiology, 68, 25, 38, Elsevier BV, 2026年08月, ［査読有り］, ［筆頭著者］
研究論文（学術雑誌） - Feasibility of Shear Wave Elastography and Dispersion Imaging in the Evaluation of Hepatic and Renal Congestion in Dogs
Nozomi Shiohara; Kensuke Nakamura; Keitaro Morishita; Nozomu Yokoyama; Mei Sugawara‐Suda; Mitsuyoshi Takiguchi
Veterinary Radiology & Ultrasound, 66, 6, Wiley, 2025年10月05日, ［査読有り］, ［筆頭著者］
研究論文（学術雑誌）, ABSTRACT
When heart disease progresses to heart failure, congestion develops in various organs, including the liver and kidneys. Although organ congestion is a critical factor closely associated with the prognosis of heart failure, a simple and quantitative method for evaluating the degree of organ congestion has not yet been established. Two‐dimensional shear wave elastography (2D‐SWE) is a noninvasive ultrasound technique that can estimate tissue stiffness by measuring shear wave speed (SWS), an index of tissue viscoelasticity, and dispersion slope (DS), which reflects tissue viscosity alone. This study aimed to assess the utility of SWS and DS in evaluating hepatic and renal congestion in transfused dogs by performing 2D‐SWE before and after blood transfusion. The ratio of the short diameter (SD) to the long diameter (LD) of the caudal vena cava (CVC SD/LD) was used as an index of congestion. Twenty transfusions were administered to 17 dogs. After transfusion, both the liver and kidney SWS and DS, along with CVC SD/LD, significantly increased. A moderate positive correlation was observed between the CVC SD/LD and liver SWS ( r = 0.781, p < 0.01) and kidney SWS ( r = 0.744, p < 0.01). Conversely, a strong positive correlation was found between the CVC SD/LD and liver DS ( r = 0.900, p < 0.01) and kidney DS ( r = 0.850, p < 0.01). These findings suggest that 2D‐SWE may be a valuable tool for assessing liver and kidney congestion, with DS potentially serving as a reliable indicator of congestion. - Peliosis Hepatis with Chylous Ascites in a Dog
Kevin Christian Montecillo Gulay; Noriyuki Nagata; Keisuke Aoshima; Nozomi Shiohara; Atsushi Kobayashi; Mitsuyoshi Takiguchi; Takashi Kimura
Journal of Comparative Pathology, 187, 63, 67, Elsevier BV, 2021年08月
研究論文（学術雑誌）
