研究者基本情報

• Ph.D

• https://researchmap.jp/dibwedf

• https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201901013638463040
• https://orcid.org/0000-0003-3433-3834

• https://orcid.org/0000-0003-3433-3834

• 201901013638463040

• ライフサイエンス, 薬系化学、創薬科学

研究活動情報

• Antioxidant Clove Extract Inhibits Lipid Droplet Accumulation and Lipid Oxidation in Hepatocytes
  Satomi Monde; Dya Fita Dibwe; Shion Iwasaki; Shu-Ping Hui
  METABOLITES, 16, 1, 2025年12月22日
  英語, 研究論文（学術雑誌）
• Inhibition of Triacylglycerol Accumulation and Oxidized Hydroperoxides in Hepatocytes by Allium cepa (Bulb)
  Dya Fita Dibwe; Saki Oba; Satomi Monde; Shu-Ping Hui
  ANTIOXIDANTS, 14, 6, 2025年05月29日
  英語, 研究論文（学術雑誌）
• Natural Bioactive Compounds Exerting Health Promoting Effects through Ameliorating Oxidative Stress: Inhibition of Lipid Accumulation and Oxidation in Hepatocytes by Bioactive Bean Extracts
  Dya Fita Dibwe; Emi Kitayama; Saki Oba; Nire Takeishi; Hitoshi Chiba; Shu-Ping Hui
  88-105, MDPI, 2025年02月11日, ［査読有り］
  論文集(書籍)内論文
• Inhibition of Accumulation of Neutral Lipids and Their Hydroperoxide Species in Hepatocytes by Bioactive Allium sativum Extract
  Dya Fita Dibwe; Saki Oba; Satomi Monde; Shu-Ping Hui
  Antioxidants, 13, 11, 1310, 1310, MDPI AG, 2024年10月28日
  研究論文（学術雑誌）, Our ongoing research suggests that extracts from plant-based foods inhibit the accumulation of lipid droplets (LDs) and oxidized lipid droplets (oxLDs) in liver cells. These findings suggest their potential use in the alleviation of metabolic dysfunction-associated fatty liver disease (MAFLD) and its most severe manifestation, metabolic dysfunction-associated steatohepatitis (MASH). Allium extracts (ALs: AL1–AL9) were used to assess their ability to reduce lipid droplet accumulation (LDA) and oxidized lipid droplet accumulation (oxLDA) by inhibiting neutral lipid accumulation and oxidation in LD. Among the tested Allium extracts, AL1, AL3, and AL6 demonstrated substantial inhibitory effects on the LDA. Furthermore, AL1 extract showed real-time inhibition of LDA in HepG2 cells in DMEM supplemented with oleic acid (OA) within 12 h of treatment. Our lipidomic approach was used to quantify the accumulation and inhibition of intracellular triacylglycerol (TAG) and oxidized TAG hydroperoxide [TG (OOH) n = 3] species in hepatocytes under OA and linoleic acid loading conditions. These results suggest that Allium-based foods inhibit LD accumulation by decreasing intracellular lipids and lipid hydroperoxides in the hepatocytes. The metabolomic analysis of AL1—the bioactive LDAI extract—using both LC-MS/MS and 1D-NMR [1H, 13C, and Dept (135 and 90)] approaches revealed that AL1 contains mainly carbohydrates and glucoside metabolites, including iridoid glucosides, as well as minor amino acids, organosulfur compounds, and organic acids such as the antioxidant ascorbic acid (KA2 = S13), and their derivatives, suggesting that AL1 could be a potential resource for the development of functional foods and in drug discovery targeting MAFLD/MASH and other related diseases.
• Inhibition of Lipid Accumulation and Oxidation in Hepatocytes by Bioactive Bean Extracts
  Dya Fita Dibwe; Emi Kitayama; Saki Oba; Nire Takeishi; Hitoshi Chiba; Shu-Ping Hui
  Antioxidants, 13, 5, 513, 513, MDPI AG, 2024年04月25日
  研究論文（学術雑誌）, During our search for natural resources that can inhibit lipid droplet accumulation (LDA) and potentially prevent metabolic dysfunction-associated fatty liver disease (MAFLD) and its progressive stages, such as metabolic dysfunction-associated steatohepatitis (MASH), eight bean extracts (BE1–BE8) were tested for their ability to inhibit lipid accumulation and oxidation in hepatocytes. Substantial inhibitory effects on LDA with bean extracts (BEs) BE2, BE4, BE5, and BE8 were demonstrated. An advanced lipidomic approach was used to quantify the accumulation and inhibition of intracellular triacylglycerol (TAG) and its oxidized species, TAG hydroperoxide (TGOOH), in hepatocytes under fatty acid-loading conditions. The results show that the antioxidants BE2 and BE8 are potential candidates for regulating TAG and TGOOH accumulation in fatty acid-induced lipid droplets (LDs). This study suggests that bean-based foods inhibit LDs formation by decreasing intracellular lipids and lipid hydroperoxides in the hepatocytes. The metabolic profiling of BEs revealed that BE2 and BE8 contained polyphenolic compounds. These may be potential resources for the development of functional foods and drug discovery targeting MAFLD/MASH.
• Identification of a β-Carboline Alkaloid from Chemoselectively Derived Vanilla Bean Extract and Its Prevention of Lipid Droplet Accumulation in Human Hepatocytes (HepG2)
  Dya Fita Dibwe; Nire Takeishi; Saki Oba; Akiko Sakurai; Toshihiro Sakurai; Takayuki Tsukui; Hitoshi Chiba; Shu-Ping Hui
  Molecules, 28, 24, 8024, 8024, MDPI AG, 2023年12月09日
  研究論文（学術雑誌）, Targeting bioactive compounds to prevent lipid droplet accumulation in the liver, we explored an antioxidative extract from vanilla bean (Vainilla planifolia) after chemo-selective derivatization through heating and acid modification. The chemical analysis of vanilla bean extract through chemoselective derivatization resulted in the identification of sixteen compounds (34–50) using LC-MS/MS analysis. A β-carboline alkaloid with a piperidine C-ring and a vanillin moiety at C-1 (34) was identified by molecular networking and diagnostic fragmentation filtering approaches. β-carboline alkaloid 34 exhibited significant inhibitory activity of lipid droplet accumulation (LDAI) in oleic acid-loaded hepatocellular carcinoma HepG2 cells. The LDAI activity was associated with both activation of lipolysis and suppression of lipogenesis in the cells. The study indicates that crude plant extracts, following chemoselective derivatization, may contain bioactive compounds that could be beneficial in preventing hepatosteatosis and could serve as a source of lead compounds for drug development. This approach may be useful to investigate other mixtures of natural products and food resources.
• New Theonellapeptolides from Indonesian Marine Sponge Theonella swinhoei as Anti-austerity Agents
  Jabal Haedar; Agustinus Uria; Subehan Lallo; Dya Fita Dibwe; Toshiyuki Wakimoto
  Marine Drugs, 20, 11, 661, 661, MDPI AG, 2022年10月25日
  研究論文（学術雑誌）, We reported three new members of the theonellapeptolide family from theonellapeptolide II series, namely theonellapeptolides IIb (1), IIa (2), IIc (3), and three known members—IId (4), IIe (5), and Id (6)—from Kodingarengan marine sponge Theonella swinhoei collected in Makassar, Indonesia. The structures of tridecadepsipeptides 1–3, including the absolute configurations of their amino acids, were determined by the integrated NMR and tandem MS analyses followed by Marfey’s analysis. To the best of our knowledge, 1 and 2 are the first theonellapeptolide-type compounds to have a valine residue with D configuration at residue position 6. The isolated theonellapeptolide-type compounds 1–6 showed selective cytotoxic activity against human pancreatic MIA PaCa-2 cancer cells in a nutrient-deprived medium. Among them, the most potent preferential cytotoxicity was observed in new theonellapeptolide IIc (3) and known IId (4), IIe (5), and Id (6).
• Abietane diterpenes from Abies spectabilis and their anti-pancreatic cancer activity against the MIA PaCa-2 cell line
  Nguyen Duy Phan; Ashraf M. Omar; Sijia Sun; Juthamart Maneenet; Dya Fita Dibwe; Mao Sato; Surya Kant Kalauni; Naoki Toyooka; Tsutomu Fujii; Suresh Awale
  Bioorganic and Medicinal Chemistry Letters, 66, 2022年06月15日
  研究論文（学術雑誌）
• Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes
  Dya Fita Dibwe; Saki Oba; Nire Takeishi; Toshihiro Sakurai; Takayuki Tsukui; Hitoshi Chiba; Shu-Ping Hui
  Pharmaceuticals, 15, 5, 578, 578, {MDPI} {AG}, 2022年05月05日, ［国際誌］
  英語, 研究論文（学術雑誌）, Lipid droplet accumulation (LDA) in hepatocytes is the initial stage of nonalcoholic fatty liver disease (NAFLD). In the search for natural compounds for the prevention of NAFLD, a series of β-carboline alkaloid derivatives, inspired by flazin and its derivative, newly identified in Crassostrea gigas Thunberg. extracts, were examined for LDA inhibition (LDAI) activity in oleic acid-loaded hepatocytes (HepG2). Eight compounds with a piperidine or pyridine C-ring were chemically synthesized (1-8). Among them, compounds 2 and 4 (flazin) with a carboxy group at C-3 and furfuryl alcohol moiety at C-1 showed low cytotoxicity and they exhibited significant LDAI activity. Compound 2 with piperidine C-ring was identified for the first time in C. gigas extract, and ameliorated the lipid accumulation with the LDAI value of 25.4%. Active compounds 2 and 4 significantly inhibited triacylglycerol species accumulation in cells. These compounds upregulated ATGL and downregulated SREBP1, FASN, and SCD1 genes, suggesting that they activated lipolysis and suppressed lipogenesis, respectively. These results suggest that β-carboline alkaloids, especially compounds 2 and 4, might be potentially useful for preventing NAFLD.
• A new anti-austerity agent, 4 '-O-methylgrynullarin from Derris scandens induces PANC-1 human pancreatic cancer cell death under nutrition starvation via inhibition of Akt/mTOR pathway
  Sijia Sun; Dya Fita Dibwe; Min Jo Kim; Ashraf M. Omar; Nguyen Duy Phan; Haruka Fujino; Nusrin Pongterdsak; Kritsaya Chaithatwatthana; Ampai Phrutivorapongkul; Suresh Awale
  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 40, 2021年05月
  英語, 研究論文（学術雑誌）
• Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice
  Lin Umeyama; Besse Hardianti; Shiori Kasahara; Dya Fita Dibwe; Suresh Awale; Satoru Yokoyama; Yoshihiro Hayakawa
  BMC COMPLEMENTARY MEDICINE AND THERAPIES, 21, 1, 2021年04月
  英語, 研究論文（学術雑誌）
• Anti-Austerity Activity of Thai Medicinal Plants: Chemical Constituents and Anti-Pancreatic Cancer Activities of Kaempferia parviflora
  Sijia Sun; Min Jo Kim; Dya Fita Dibwe; Ashraf M. Omar; Sirivan Athikomkulchai; Ampai Phrutivorapongkul; Takuya Okada; Kiyoshi Tsuge; Naoki Toyooka; Suresh Awale
  PLANTS-BASEL, 10, 2, 2021年02月
  英語, 研究論文（学術雑誌）
• Highly oxygenated spiro-biflavanoids from Anneslea fragrans twigs
  Ashraf M. Omar; Sijia Sun; Min Jo Kim; Ahmed M. Tawila; Dya Fita Dibwe; Ampai Phrutivorapongkul; Naoki Toyooka; Suresh Awale
  PHYTOCHEMISTRY LETTERS, 40, 21, 25, 2020年12月
  英語, 研究論文（学術雑誌）
• A Triterpene Lactone fromCallistemon citrinusInhibits the PANC-1 Human Pancreatic Cancer Cells Viability through Suppression of Unfolded Protein Response
  Ahmed M. Tawila; Sijia Sun; Min Jo Kim; Ashraf M. Omar; Dya Fita Dibwe; Suresh Awale
  CHEMISTRY & BIODIVERSITY, 17, 10, 2020年10月
  英語, 研究論文（学術雑誌）
• Chemical constituents of Callistemon citrinus from Egypt and their antiausterity activity against PANC-1 human pancreatic cancer cell line
  Ahmed M. Tawila; Sijia Sun; Min Jo Kim; Ashraf M. Omar; Dya Fita Dibwe; Jun-ya Ueda; Naoki Toyooka; Suresh Awale
  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 30, 16, 2020年08月
  英語, 研究論文（学術雑誌）
• Thiosemicarbazone(s)-anchored water soluble mono- and bimetallic Cu(ii) complexes: enzyme-like activities, biomolecular interactions, anticancer property and real-time live cytotoxicity
  Nithya Balakrishnan; Jebiti Haribabu; Ananda Krishnan Dhanabalan; Srividya Swaminathan; Sijia Sun; Dya Fita Dibwe; Nattamai Bhuvanesh; Suresh Awale; Ramasamy Karvembu
  DALTON TRANSACTIONS, 49, 27, 9411, 9424, 2020年07月
  英語, 研究論文（学術雑誌）
• Fragranol A: A new class of spiro-triflavanoid hybrid with an unprecedented carbon skeleton from Anneslea fragrans
  Ashraf M. Omar; Sijia Sun; Min Jo Kim; Ahmed M. Tawila; Dya Fita Dibwe; Ampai Phrutivorapongkul; Naoki Toyooka; Suresh Awale
  TETRAHEDRON LETTERS, 61, 29, 2020年07月
  英語, 研究論文（学術雑誌）
• Highly Potent Antiausterity Agents from Callistemon citrinus and Their Mechanism of Action against the PANC-1 Human Pancreatic Cancer Cell Line
  Ahmed M. Tawila; Sijia Sun; Min Jo Kim; Ashraf M. Omar; Dya Fita Dibwe; Jun-ya Ueda; Naoki Toyooka; Suresh Awale
  JOURNAL OF NATURAL PRODUCTS, 83, 7, 2221, 2232, 2020年07月
  英語, 研究論文（学術雑誌）
• Antiausterity Activity of Secondary Metabolites from the Roots of Ferula hezarlalehzarica against the PANC-1 Human Pancreatic Cancer Cell Line
  Mostafa Alilou; Dya Fita Dibwe; Stefan Schwaiger; Mojtaba Khodami; Jakob Troppmair; Suresh Awale; Hermann Stuppner
  JOURNAL OF NATURAL PRODUCTS, 83, 4, 1099, 1106, 2020年04月
  英語, 研究論文（学術雑誌）
• Fragranone C: a new dihydrochalcone glucopyranoside from Anneslea fragrans twigs
  Ashraf M. Omar; Dya Fita Dibwe; Sijia Sun; Ahmed M. Tawila; Min Jo Kim; Ampai Phrutivorapongkul; Naoki Toyooka; Suresh Awale
  NATURAL PRODUCT RESEARCH, 2020年04月
  英語, 研究論文（学術雑誌）
• Synthesis of guggulsterone derivatives as potential anti-austerity agents against PANC-1 human pancreatic cancer cells
  Aki Kohyama; Rei Yokoyama; Dya Fita Dibwe; Sahar El-Mekkawy; Meselhy R. Meselhy; Suresh Awale; Yuji Matsuya
  Bioorganic & Medicinal Chemistry Letters, 30, 7, 126964, 126964, 2020年04月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti-Austerity Activity against Human PANC-1 Pancreatic Cancer Cells
  Benjamin E. Alexander; Sijia Sun; Matthew J. Palframan; Gabriele Kociok-Kohn; Dya Fita Dibwe; Shiro Watanabe; Lorenzo Caggiano; Suresh Awale; Simon E. Lewis
  CHEMMEDCHEM, 15, 1, 125, 135, 2020年01月
  英語, 研究論文（学術雑誌）
• Chemical constituents from Artemisia vulgaris and their antiausterity activities against the PANC-1 human pancreatic cancer cell line
  Ashraf M. Omar; Dya Fita Dibwe; Ahmed M. Tawila; Sijia Sun; Min Jo Kim; Suresh Awale
  NATURAL PRODUCT RESEARCH, 2019年12月
  英語, 研究論文（学術雑誌）
• Chemical Constituents of Anneslea fragrans and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line
  Ashraf M. Omar; Dya Fita Dibwe; Ahmed M. Tawila; Sijia Sun; Ampai Phrutiyorapongkul; Suresh Awale
  JOURNAL OF NATURAL PRODUCTS, 82, 11, 3133, 3139, 2019年11月
  英語, 研究論文（学術雑誌）
• Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism
  Qing-Yun Guo; Ken Ebihara; Takafumi Shimodaira; Hironori Fujiwara; Kazufumi Toume; Dya Fita Dibwe; Suresh Awale; Ryota Araki; Takeshi Yabe; Kinzo Matsumoto
  PLOS ONE, 14, 1, 2019年01月
  英語, 研究論文（学術雑誌）
• Orengedokuto and san’oshashinto improve memory deficits by inhibiting age-dependent GSK-3β activation and subsequent CRMP2 phosphorylation in senescence-accelerated prone 8 mice
  Fujiwara H; Yoshida J; Dibwe D.F; Awale S; Hoshino H; Kohama H; Arai H; Kudo Y; Matsumoto K
  J Tradit Complement Med, 9, 4, 328, 335, 2019年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Kami-shoyo-san ameliorates ASD-like behaviors by inhibiting allopregnanolone biosynthesis in the brain via dopaminergic and, in part, GABAergic mechanisms
  Guo Q.Y; Ebihara K; Shimodaira T; Fujiwara H; Toume K; Dibwe D.F; Awale S; Araki R; Yabe T; Matsumoto K
  PLoS ONE, 2019年, ［査読有り］
• Design and synthesis of functionalized coumarins as potential anti-austerity agents that eliminates cancer cells tolerance to nutrition starvation
  Awale S; Okada T; Dibwe D.F; Maruyama T; Takahara S; Okada T; Endo S; Toyooka
  Bioorg. Med. Chem Lett, 23, 14, 1779, 1784, 2019年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Chemical constituents of Thai Citrus hystrix and their antiausterity activity against the PANC-1 Human Pancreatic Cancer Cell Line
  Sun S; Phrutivorapongkul A; Dibwe D. F; Balachandran, C; Awale S
  J. Nat. Prod., 81, 8, 1877, 1883, 2018年08月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Ancistroyafungines A-D, 5,8′- and 5,1′-coupled naphthylisoquinoline alkaloids from a Congolese Ancistrocladus species, with antiausterity activities against human PANC-1 pancreatic cancer cells.
  Muyisa S; Lombe B.K; Doris Feineis; Dibwe D.F; Maharaj V; Awale S. Bringmann G
  Fitoterapia, 130, 6, 16, 2018年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Ancistrolikokine E3, a 5,8'-coupled naphthylisoquinoline alkaloid, eliminates the cancer cells tolerance to nutrition starvation by inhibition of the Akt/mTOR/autophagy signaling pathway.
  Awale S; Dibwe D.F; Chandrasekar B; Shaimaa F; Doris; Kimbadi B.L; Bringmann G
  J. Nat. Prod.,, 81, 10, 2282, 2291, 2018年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3β
  Fujiwara, H; Yoshida, J; Dibwe, D.F; Awale, S; Hoshino, H; Kohama, H; Araki, H; Kudo, M; Matsumto, K
  Journal of Traditional and Complementary Medecine, 9, 4, 328, 335, 2018年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Discovery of potential antiausterity agents from the Japanese cypress Chamaecyparis obtusa
  Dya Fita Dibwe; Sijia Sun; Jun-ya Ueda; Chandrasekar Balachandran; Kinzo Matsumoto; Suresh Awale
  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 27, 21, 4898, 4903, 2017年11月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Decrease in endogenous brain allopregnanolone induces autism spectrum disorder (ASD)-like behavior in mice: A novel animal model of ASD
  Ken Ebihara; Hironori Fujiwara; Suresh Awale; Dya Fita Dibwe; Ryota Araki; Takeshi Yabe; Kinzo Matsumoto
  BEHAVIOURAL BRAIN RESEARCH, 334, 6, 15, 2017年09月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Syntheses of benzophenone-xanthone hybrid polyketides and their antibacterial activities
  Takeshi Kodama; Takuya Ito; Dya Fita Dibwe; So-Yeun Woo; Hiroyuki Morita
  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 27, 11, 2397, 2400, 2017年06月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Sex difference in autism spectrum disorder (ASD)-like behaviors caused by allopregnanolone (ALLO) biosynthesis inhibition and distribution of ALLO in the brain
  Ken Ebihara; Hironori Fujiwara; Dya Fita Dibwe; Suresh Awale; Ryota Araki; Takeshi Yabe; Kinzo Matsumoto
  JOURNAL OF PHARMACOLOGICAL SCIENCES, 133, 3, S224, S224, 2017年03月
  英語
• Constituents of the rhizomes of Boesenbergia pandurata and their antiausterity activities against the PANC-1 human pancreatic cancer line
  Nguyen, N; Nguyen, M; Nguyen, H; Dang, P; Dibwe, D. F; Esumi, H; Awale, S
  J. Nat. Prod., 2017, 80, 141-148, 80, 1, 141, 148, 2017年01月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Highly oxygenated antiausterity agents from the leaves of Uvaria dac
  Suresh Awale; Ahmed M. Tawila; Dya Fita Dibwe; Jun-ya Ueda; Sijia Sun; Sirivan Athikomkulchai; Chandrashaker Balachandran; Ikuo Saiki; Kinzo Matsumoto; Hiroyasu Esumi
  Bioorganic and Medicinal Chemistry Letters, 27, 9, 1967, 1971, 2017年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Evaluation of synthetic coumarins for antiausterity cytotoxicity against pancreatic cancers
  Farley, C. M; Dibwe, D. F; Ueda J; Hall E.A; Awale S; Magolan J
  Bioorg. Med. Chem Lett, 2016, 26, 1471−1474., 26, 5, 1471, 1474, 2016年03月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Cassane diterpenes from the seed kernels of Caesalpinia sappan
  Hai Xuan Nguyen; Nhan Trung Nguyen; Phu Hoang Dang; Phuoc Thi Ho; Mai Thanh Thi Nguyen; Mao Van Can; Dya Fita Dibwe; Jun-ya Ueda; Suresh Awale
  PHYTOCHEMISTRY, 122, 286, 293, 2016年02月
  英語, 研究論文（学術雑誌）
• A new cassane-type diterpene from the seed of caesalpinia sappan
  Hai Xuan Nguyen; Nhan Trung Nguyen; Phu Hoang Dang; Phuoc Ho Thi; Mai Thanh Thi Nguyen; Mao Van Can; Dya Fita Dibwe; Jun-Ya Ueda; Kinzo Matsumoto; Suresh Awale
  Natural Product Communications, 11, 6, 723, 724, 2016年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Anti-austeritic constituents of Congolese medicinal plant Aframomum melegueta
  Dibwe, D. F; Awale, S; Morita, H; Tezuka, Y
  Nat. Prod. Commun, 2015, 10, 997−999, 10, 6, 997, 999, 2015年06月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Muchimangins E and F: novel diphenylmethyl-substituted xanthones from Securidaca longepedunculata.
  Dibwe, D. F; Awale, S; Kadota, S; Morita, H; Tezuka, Y
  Tetrahedron Lett, , 2014, 55, 1916-1919., 55, 11, 1916, 1919, 2014年03月, ［査読有り］
  英語, 研究論文（学術雑誌）
• New guaian-type sesquiterpene from Wikstroemia indica
  Mamoru Kato; Yu-Min He; Dya Fta Dibwe; Feng Li; Suresh Awale; Shigetoshi Kadota; Yasuhiro Tezuka
  Natural Product Communications, 9, 1, 1, 2, 2014年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Antiausterity activity of arctigenin enantiomers: Importance of (2R,3R)-absolute configuration
  Suresh Awale; Mamoru Kato; Dya Fita Dibwe; Feng Li; Chika Miyoshi; Hiroyasu Esumi; Shigetoshi Kadota; Yasuhiro Tezuka
  Natural Product Communications, 9, 1, 79, 82, 2014年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Two New Diphenylmethyl-substituted Xanthones from Securidaca longepedunculata
  Dya Fita Dibwe; Suresh Awale; Shigetoshi Kadota; Hiroyuki Morita; Yasuhiro Tezuka
  Natural Product Communications, 9, 5, 655, 657, 2014年, ［査読有り］
  英語, 研究論文（学術雑誌）
• A new polyoxygenated cyclohexane and other constituents from Kaempferia rotunda and their cytotoxic activity
  Subehan, Lee S; Dibwe D. F; Tezuka Y; Morita H
  Natural Product Research, 28, 20, 1754, 1759, 2014年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Heptaoxygenated xanthones as anti-austerity agents from Securidaca longepedunculata.
  Dibwe D. F; Awale, S; Kadota, S; Morita H; Tezuka, Y
  Bioorg. Med. Chem, 2013, 21, 7663-7668., 21, 24, 7663, 7668, 2013年12月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Synthesis and antitumor evaluation of arctigenin derivatives based on antiausterity strategy
  Kudou N; Taniguchi A; Sugimoto K; Matsuya Y; Kawasaki M; Toyooka N; Miyoshi C; Awale S; Dibwe D. F; Esumi H; Kadota S; Tezuka Y
  Eur. J. Med. Chem., 2013, 60, 76-88., 60, 76, 88, 2013年02月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Damnacanthal from the Congolese medicinal plant Garcinia huillensis has a potent preferential cytotoxicity against human pancreatic cancer PANC-1 cells.
  Dibwe D. F; Awale, S; Kadota, S; Tezuka, Y
  Phytother. Res, 2012, 26, 1920-1926., 26, 12, 1920, 1926, 2012年12月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Muchimangins A–D: novel diphenylmethyl-substituted xanthones from Securidaca longepedunculata.
  Dibwe D. F; Awale, S; Kadota, S; Tezuka, Y
  Tetrahedron Lett, 2012, 53, 6186-6190., 53, 46, 6186, 6190, 2012年11月, ［査読有り］
  英語, 研究論文（学術雑誌）
• Anti-austerity agents from Rhizoma et Radix Notopterygii (Qianghuo)
  Feng Li; Yukari Okamura; Dyafita Dibwe; Suresh Awale; Shigetoshi Kadota; Yasuhiro Tezuka
  Planta Medica, 78, 8, 796, 799, 2012年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Uvaridacols E-H, highly oxygenated antiausterity agents from Uvaria dac
  Suresh Awale; Jun-Ya Ueda; Sirivan Athikomkulchai; Dya Fita Dibwe; Sherif Abdelhamed; Satoru Yokoyama; Ikuo Saiki; Ryuta Miyatake
  Journal of Natural Products, 75, 11, 1999, 2002, 2012年, ［査読有り］
  英語, 研究論文（学術雑誌）
• Muchimangins G-J: fully-substituted xanthones with a diphenylmethyl substitutent from Securidaca longepedunculata
  Dibwe, D. F; Awale, S; Kadota, S; Morita, H; Tezuka, Y
  J. Nat. Prod., 2014, 77 (5), 1241–1244., ［査読有り］
• Tshilanda, D. D, Onyamboko, D. N, Babady-B, P, Ngbolua, K. N; Tshibangu, D. S, Dibwe, D. F., Mpiana, P. T.
  Anti-sickling activity; ursolic acid; isolated; from the; leaves of Ocimum; gratissimum L. (Lamiaceae
  Nat. Prod. Bioprospect. 2015, 5 (4), 215-221., ［査読有り］
• Preferential cytotoxicity of crude drugs used in Kampo medicines against human pancreatic cancer PANC-1 and PSN-1 cells
  Lee, S; Dibwe; D. F; Feng, Li; Morita, H; Tezuka, Y
  Traditional & kampo medicine, 2015, 2 (2), 35-−42., ［査読有り］
• Syntheses of benzophenone- xanthone hybrid polyketides and their antibacterial activities
  Kodama, T; Ito, T; Dibwe, D.F; Woo, S-Y; Morita, H
  Bioorg. Med. Chem Lett, 26, 1471, 1474, ［査読有り］

• Discovery of potential antiausterity agents from Thai Piper ribesoides
  Dibwe D.F
  The 139th Annual Meeting of the Pharmaceutical Society of Japan., 2019年03月
• Discovery of anti-austerity agents from Derris scandens
  Dibwe D. F
  The 65th Annual Meeting of the Japanese Society of Pharmacognosy, 2018年09月14日
• Prenylated isoflavones from Thai Derris scandens and their anti-austerity activity
  Dibwe D.F
  The 5th Toyama-Basel Joint Symposium on Pharmaceutical Research and Drug Development, 2018年08月
• Discovery of potential anti austerity agents from Thai Derris scandens
  Dibwe D.F
  The 138th Annual Meeting of the Pharmaceutical Society of Japan , Kanazawa, 2018年03月
• Chemical Constituents of Piper longum and their Antiausterity activity
  Dibwe D.F
  Toyama Science Gala 2017, 2017年09月