姚 遠 (ヨウ エン)
| 北方生物圏フィールド科学センター 水圏ステーション 厚岸臨海実験所 | 博士研究員 |
研究者基本情報
■ URLresearchmap URLホームページURL■ ID 各種研究者番号ORCID IDJ-Global ID■ 研究キーワード・分野研究キーワード攪乱
群集生態学
ブルーカーボン
岩礁潮間帯
種間相互作用
研究分野研究活動情報
■ 論文Port construction increases community variability without directional change in adjacent rocky intertidal communities: a BACI analysis from eastern Hokkaido, JapanYuan Yao; Hiroto Imatake; Masahiro Nakaoka; Takashi Noda
2026年05月05日
Coastal infrastructure such as ports and breakwaters can substantially alter hydrodynamic conditions, yet their long-term ecological consequences for adjacent natural habitats remain poorly understood. Here, we used a long-term before–after–control–impact (BACI) design to evaluate the effects of port construction on rocky intertidal communities along the Pacific coast of eastern Hokkaido, Japan. We analyzed changes in abundance, diversity metrics (Hill’s numbers), and community structure across four major functional groups using a 10-year dataset spanning five-year period before construction and a five-year period beginning eight years after port construction across one impact and four control shores. Results showed that port construction did not induce a consistent directional shift in community composition, but instead increased variability in community structure at the impacted shore. This change was associated with a pronounced, direction-specific reduction in wave exposure caused by the offshore breakwater. At the functional-group level, responses were limited, with significant declines detected only in herbivorous molluscs, whereas species-level responses were highly heterogeneous within and among groups. Diversity responses were group-specific and primarily reflected changes in evenness and dominance rather than species richness. Wave exposure explained a significant but modest proportion of variation in community structure with species-specific effects. Together, these results indicate that port construction weakens wave-driven environmental filtering, leading to increased variability rather than deterministic shifts in community structure. Our findings emphasize that evaluating the ecological impacts of coastal infrastructure requires moving beyond mean responses to explicitly account for changes in variability and community predictability. Proton therapy (PT) combined with concurrent chemotherapy for locally advanced non-small cell lung cancer with negative driver genesYonglong Jin; Shosei Shimizu; Yinuo Li; Yuan Yao; Xiguang Liu; Hongzong Si; Hideyuki Sakurai; Wenjing Xiao
Radiation Oncology, 2023年11月16日
英語, 研究論文（学術雑誌）,
Abstract
Purpose
To discuss the optimal treatment modality for inoperable locally advanced Non-Small Cell Lung Cancer patients with poor physical status, impaired cardio-pulmonary function, and negative driver genes, and provide clinical evidence.
Materials and methods
Retrospective analysis of 62 cases of locally advanced non-small cell lung cancer patients with negative driver genes treated at Tsukuba University Hospital(Japan) and Qingdao University Affiliated Hospital(China).The former received proton therapy with concurrent chemotherapy, referred to as the proton group, with 25 cases included; while the latter underwent X-ray therapy with concurrent chemoradiotherapy followed by 1 year of sequential immunomodulatory maintenance therapy, referred to as the X-ray group, with 37 cases included.The treatment response and adverse reactions were assessed using RECIST v1.1 criteria and CTCAE v3.0, and radiotherapy planning and evaluation of organs at risk were performed using the CB-CHOP method.All data were subjected to statistical analysis using GraphPad Prism v9.0, with a T-test using P < 0.05 considered statistically significant.
Results
(1)Target dose distribution: compared to the X-ray group, the proton group exhibited smaller CTV and field sizes, with a more pronounced bragg peak.(2)Organs at risk dose: When comparing the proton group to the X-ray group, lung doses (V5, V20, MLD) and heart doses (V40, Dmax) were lower, with statistical significance (P < 0.05), while spinal cord and esophagus doses showed no significant differences between the two groups (P > 0.05).(3)Treatment-related toxicities: The incidence of grade 3 or higher adverse events in the proton group and X-ray group was 28.6% and 4.2%, respectively, with a statistically significant difference (P < 0.05). In terms of the types of adverse events, the proton group primarily experienced esophagitis and pneumonia, while the X-ray group primarily experienced pneumonia, esophagitis, and myocarditis. Both groups did not experience radiation myelitis or esophagotracheal fistula.(4)Efficacy evaluation: The RR in the proton group and X-ray group was 68.1% and 70.2%, respectively (P > 0.05), and the DCR was 92.2% and 86.4%, respectively (P > 0.05), indicating no significant difference in short-term efficacy between the two treatment modalities.(5)Survival status: The PFS in the proton group and X-ray group was 31.6 ± 3.5 months (95% CI: 24.7 ~ 38.5) and 24.9 ± 1.55 months (95% CI: 21.9 ~ 27.9), respectively (P > 0.05), while the OS was 51.6 ± 4.62 months (95% CI: 42.5 ~ 60.7) and 33.1 ± 1.99 months (95% CI: 29.2 ~ 37.1), respectively (P < 0.05).According to the annual-specific analysis, the PFS rates for the first to third years in both groups were as follows: 100%, 56.1% and 32.5% for the proton group vs. 100%, 54.3% and 26.3% for the X-ray group. No statistical differences were observed at each time point (P > 0.05).The OS rates for the first to third years in both groups were as follows: 100%, 88.2%, 76.4% for the proton group vs. 100%, 91.4%, 46.3% for the X-ray group. There was no significant difference in the first to second years (P > 0.05), but the third year showed a significant difference (P < 0.05). Survival curve graphs also depicted a similar trend.
Conclusion
There were no significant statistical differences observed between the two groups in terms of PFS and OS within the first two years. However, the proton group demonstrated a clear advantage over the X-ray group in terms of adverse reactions and OS in the third year. This suggests a more suitable treatment modality and clinical evidence for populations with frail health, compromised cardio-pulmonary function, post-COVID-19 sequelae, and underlying comorbidities.
The impact of marine heatwaves on rocky intertidal communities: evidence of accumulative carryover effects of marine heatwavesKen Ishida; Michikusa Tachibana; Yuan Yao; Yoko Wada; Takashi Noda
Frontiers in Marine Science, 2023年04月28日
研究論文（学術雑誌）,
The frequency and duration of marine heat waves (MHWs) have recently increased. There is therefore an urgent need to understand the response of marine organisms to MHWs. However, most estimates of MHW impacts on abundances include the effects of environmental stochasticity other than the MHWs. In addition, although MHWs sometimes persist for year-round or occur repeatedly for shorter periods, the accumulative carryover effects (ACEs)— the effects of sequential events accumulating additively over time— of MHWs on organisms have never been evaluated. Furthermore, the relationship between species niche traits other than thermal niches and susceptibility to MHWs is unknown. We examined the impacts of MHWs in southeastern Hokkaido, northern Japan, in summer from 2010 to 2016 on rocky intertidal communities by distinguishing MHW effects from environmental stochasticity. We asked (1) Did MHWs have ACEs on four major functional groups: macroalgae, sessile invertebrates, herbivorous invertebrates, and carnivorous invertebrates? (2) Does ignoring ACEs lead to biased assessments? (3) How did the effects of the MHWs on functional groups and their subsequent recovery differ? And (4) How does the susceptibility to MHWs differ with species niche (thermal and vertical) traits? We detected ACEs of MHWs and found that if they are ignored, the effects of MHWs can be underestimated. Although MHWs are known to reduce the abundance of macroalgae and increase that of sessile invertebrates in rocky intertidal habitats, our results show that macroalgal abundance increased during and after MHWs, whereas sessile invertebrates showed no change during or after MHWs. The abundance of herbivorous mollusks decreased during and after MHWs. Carnivorous invertebrates declined during MHWs and in the first year after MHWs. During and after MHWs, abundances of species with low thermal niches decreased and those with high thermal niches increased. There were no differences in response to MHWs between vertical niches when accumulative carryover effects were ignored. These results emphasize the importance of considering ACEs when assessing the response of marine organisms to MHWs, and that more studies of these responses are needed for a variety of ecosystems, regions and organisms to predict the responses of marine organisms.
■ 講演・口頭発表等Context dependence of coexistence between two rocky intertidal sessile species Chthamalus dalli and Gloiopeltis furcate
Yuan YAO; Takashi NODA
Annual Meeting of Ecological Society of Japan, 2025年03月18日, 英語, シンポジウム・ワークショップパネル（指名）
自然攪乱に対する生物群集の多次元安定性の評価: 岩礁潮間帯を例に
石田拳; 山北剛久; 和田葉子; 金森由妃; 姚遠; 野田隆史
日本生態学会, 2025年03月17日, 日本語, 口頭発表（一般）
岩礁潮間帯固着生物群集における2 種系（キタイワフジツボとフクロフノリ）の 種間相互作用の環境依存性
姚遠; 野田隆史
日本生態学会北海道地区大会, 2023年12月09日, 日本語, 口頭発表（一般）
Detecting causal relationship among multiple variables by SEM: a case study in rocky intertidal sessile community
Yuan YAO
39th Annual Meeting of the Society of Population Ecology, 2023年10月28日, 英語, 口頭発表（招待・特別）
Impact of harmful algal bloom in 2021 off southeastern Hokkaido on rocky intertidal community
Yuan YAO; Takashi NODA
Annual Meeting of Ecological Society of Japan, 2023年03月17日, 口頭発表（一般）
Context dependence of population dynamics in rocky intertidal sessile assemblages: Using intrinsic growth rate as a proxy of environmental suitability
Yuan YAO; Keiichi FUKAYA; Takashi NODA
Annual Meeting of Ecological Society of Japan, 2022年03月14日, 口頭発表（一般）
2021年に生じた赤潮が北海道東部の岩礁潮間帯生物群集に及ぼす影響
姚遠; 立花道草; 藤井玲於奈; 米田智樹; 劉小河; 新井慧; 稲富楽; 岩﨑藍子; 野田隆史
日本生態学会北海道地区大会, 2021年12月18日, 口頭発表（一般）
2 種系における個体群動態の環境依存性を理解する新しい枠組み：岩礁 潮間帯固着生物群集についての事例研究
姚遠; 深谷肇一; 野田隆史
日本生態学会北海道地区大会, 2020年12月12日, 日本語, 口頭発表（一般）
■ 所属学協会■ 共同研究・競争的資金等の研究課題
