研究者データベース
Last Updated :2024/07/25
研究者情報
マスター
アカウント（マスター）
氏名
MAKANAHALLI MADEGOWDA MAHADEVA SWAMY(マカナハリ マデゴウダ マハデバ スワミイ), マカナハリ マデゴウダ マハデバ スワミイ
所属（マスター）
所属（マスター）
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プロフィール情報
所属
プロフィール情報
姓
エム. エム.名
マハデバ スワミィID各種
202201001804869147
所属
業績リスト
研究キーワード
研究分野
経歴
- 2022年04月 - 現在 Visiting scientist, RIKEN
- 2022年03月 - 現在 Assistant professor, Faculty of Advanced Life Science, Hokkaido University
- 2019年04月 - 2022年02月 Research scientist, RIKEN
- 2018年05月 - 2019年01月 Academic researcher, Hokkaido University
- 2012年05月 - 2014年08月 Research assistant, JNCASR
学歴
- 2014年10月 - 2018年03月 Doctoral degree, Graduate School of Life Science, Hokkaido University
- 2009年07月 - 2011年06月 Master's degree, University of Mysore
- 2006年06月 - 2009年05月 Bachelor's degree, University of Mysore
受賞
- 2021年10月 Best poster award RIKEN BDR retreat-2021
- 2018年10月 Japan Student Services Organization (JASSO) scholarship award
- 2014年10月 Japan government MEXT scholarship award
論文
- Mahadeva M. M. Swamy, Yuta Murai, Kenji Monde, Setsuko Tsuboi, Aravind K. Swamy, Takashi JinACS Applied Materials & Interfaces 16 17253 - 17266 2024年04月01日 [査読有り]
- Stereochemistry‐activity relationship of ceramide‐induced exosome production to clear amyloid‐β in Alzheimer's diseaseMariam Abdelrasoul, Kohei Yuyama, Mahadeva M. M. Swamy, Yuta Murai, Kenji MondeChirality 35 9 577 - 585 2023年04月 [査読有り]
- Sajeer Koolath, Yuta Murai, Tomoya Suzuki, Mahadeva M, M. Swamy, Seigo Usuki, Kenji MondeACS Med. Chem. Lett. in press 9 1237 - 1241 2023年 [査読有り]
- A near-infrared fluorescent long-chain fatty acid toward optical imaging of cardiac metabolism in living miceMahadeva M. M. Swamy, Mohamad Zarif Mohd, Zubir, Mutmainah, Setsuko Tsuboi, Yuta Murai, Kenji Monde, Ken-ichi Hiranoc, Takashi JinAnalyst 147 19 4206 - 4212 2022年08月 [査読有り]
- Shortwave-infrared (SWIR) emitting annexin V for high-contrast fluorescence molecular imaging of tumor apoptosis in living miceMahadeva M. M. Swamy, Setsuko Tsuboi, Yuta Murai, Kenji Monde, Takashi JinRSC Advances 12 30 19632 - 19639 2022年06月 [査読有り]
- Mahadeva M. M. Swamy, Yuta Murai, Kenji Monde, Setsuko Tsuboi, Takashi JinBioconjugate Chemistry 32 8 1541 - 1547 2021年08月18日 [査読有り]
Recently, shortwave-infrared (SWIR) fluorescence imaging for the optical diagnostics of diseases has attracted much attention as a new noninvasive imaging modality. For this application, the development of SWIR molecular imaging probes with high biocompatibility is crucial. Although many types of biocompatible SWIR fluorescent probes based on organic dyes have been reported, there are no SWIR-emitting molecular imaging probes that can be used for the detection of specific biomolecules in vivo. To apply SWIR-emitting molecular imaging probes to biomedical fields, we developed a biocompatible SWIR fluorescent dye based on π-conjugation extended indocyanine green (ICG), where ICG is the only approved near-infrared dye by the US Food and Drug Administration (FDA) for use in the clinic. Using the π-conjugation extended ICG, we prepared SWIR molecular imaging probes that can be used for in vivo tumor imaging. Herein, we demonstrate noninvasive SWIR fluorescence imaging of human epidermal growth factor receptor 2 (HER2)-positive and epidermal growth factor receptor (EGFR)-positive breast tumors using π-conjugation extended ICG and monoclonal antibody conjugates. The presented π-conjugation extended ICG analog probes will be a breakthrough to apply SWIR fluorescence imaging in biomedical fields. - Daurichromenic acid from the Chinese traditional medicinal plant Rhododendron dauricum inhibits sphingomyelin synthase and Aβ aggregationHadya Virupaksha Deepak, Mahadeva M. M. Swamy, Yuta Murai, Yoshiko Suga, Masaki Anetai, Takuro Yo, Masahiro Kuragano, Koji Uwai, Kiyotaka Tokuraku, Kenji MondeMolecules 25 18 4077 - 4088 2020年09月07日 [査読有り]
- Determination of the absolute configurations and sensory properties of the enantiomers of a homologous series (C6-C10) of 2-mercapto-4-alkanonesChristiane Kiske, Anja Devenie Riegel, Ronja Hopf, Anna Kvind, Iulia Poplacean, Tohru Taniguchi, Mahadeva M. M. Swamy, Kenji Monde, Wolfgang Eisenreich, Karl-Heinz EngelJ. Agric. Food Chem. 64 4 1187 - 1196 2019年01月03日 [査読有り]
- Structure-inspired design of a sphingolipid mimic sphingosine-1-phosphate receptor agonist from a naturally occurring sphingomyelin synthase inhibitorMahadeva M. M. Swamy, Yuta Murai, Yusuke Ohno, Akio Kihara, Susumu Mitsutake, Yasuyuki Igarashi, Jian Yu, Min Yao, Yoshiko Suga, Masaki Anetai, Kenji MondeChem. Commun. 54 90 12758 - 12761 2018年11月08日 [査読有り]
- Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi Syndrome in zebrafishAswini Babu, Mageshi Kamaraj, Moumita Basu, Debanjan Mukherjee, Shruti Kapoor, Shashi Ranjan, Mahadeva M. M. Swamy, Stephanie Kaypee, Vinod Scaria, Tapas K. Kundu, Chetana SachidanandanBiochim. Biophys. Acta 1864 4 1203 - 1215 2018年04月 [査読有り]
- Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasivenessSuvasmita Rath, Lopamudra Das, Shrikant Babanrao Kokate, Nilabh Ghosh, Pragyesh Dixi, Niranjan Rou, Shivaram P. Singh, Subhasis Chattopadhyay, Hassan Ashktorab, Duane T. Smoo, Mahadeva M. M. Swamy, Tapas K. Kundu, Sheila E. Crowe, Asima BhattacharyyaInt. J. Biochem. Cell Biol. 82 28 - 40 2017年01月 [査読有り]
- Reducing molecular flexibility by cyclization for elucidation of absolute configuration by CD calculations: Daurichromenic acidAttila Mandi, Mahadeva M. M. Swamy, Tohru Taniguchi, Masaki Anetai, Kenji MondeChirality 28 6 453 - 459 2016年06月 [査読有り]
- Stereochemistry of a rhododaurichromanic acid derivativeMahadeva M. M. Swamy, Attila Mándi, Masaki Anetai, Kenji MondeNat. Prod. Commun. 11 2 193 - 195 2016年02月 [査読有り]
- Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in miceMin Wu, Sahn-Ho Kim, Indrani Datta, Albert Levin, Gregory Dyson, Jing Li, Stephanie Kaypee, Mahadeva M. M. Swamy, Nilesh Gupta, Ho Jeong Kwon, Mani Menon, Tapas K. Kundu, G. Prem-Veer ReddyOncotarget 6 8 6136 - 6150 2015年03月 [査読有り]
- Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkersFeng Li, Muthu K, Shanmugam, Kodappully Sivaraman Siveen, Fan Wang, Tina H. Ong, Ser Yue Loo, Mahadeva M. M. Swamy, Somnath Mandal, Alan Prem Kumar, Boon Cher Goh, Tapas Kundu, Kwang Seok Ahn, Ling Zhi Wang, Kam Man Hui, Gautam SethiOncotarget 6 7 5147 - 5163 2015年03月 [査読有り]
- Naphthoquinone-mediated inhibition of lysine acetyltransferase KAT3B/p300, basis for non-toxic inhibitor synthesisMohankrishna Dalvoy Vasudevarao, Pushpak Mizar, Sujata Kumari, Somnath Mandal, Soumik Siddhanta, Mahadeva M. M. Swamy, Stephanie Kaypee, Ravindra C Kodihalli, Amrita Banerjee, Chandrabhas Naryana, Dipak Dasgupta, Tapas K. KunduJ. Biol. Chem. 289 11 7702 - 7717 2014年03月 [査読有り]
書籍等出版物
- Garcinol and its role in chronic diseasesAmit K. Behera, Mahadeva M. M. Swamy, Nagashayana, Tapas K. Kundu
Adv. Exp. Med. Biol. 2016年09月
産業財産権
- 特願2021-041717:Complexes and shortwave-infrared fluorescent probes, manufacturing methods and thereof 2021年Jin Takashi, M. M. Mahadeva Swamy, Monde Kenji, Murai Yuta RIKEN, Hokkaido University
- 特願2017-236847:Daurichromenic acid, naturally occurring SMS inhibitor 2017年Monde Kenji, Murai Yuta, M. M. Mahadeva Swamy Hokkaido University
- 特願2017-236846:Ginkgolic acid, naturally occurring SMS inhibitor 2017年Monde Kenji, Murai Yuta, M. M. Mahadeva Swamy Hokkaido University